Danio rerio

0 known processes

psma6a

proteasome (prosome, macropain) subunit, alpha type, 6a

psma6a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.958
Human Yeast
larval development GO:0002164 2 0.901
Worm
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.889
Yeast
modification dependent protein catabolic process GO:0019941 3 0.850
Yeast
cellular protein catabolic process GO:0044257 4 0.823
Human Yeast
modification dependent macromolecule catabolic process GO:0043632 3 0.823
Yeast
ubiquitin dependent protein catabolic process GO:0006511 3 0.782
Yeast
proteasomal protein catabolic process GO:0010498 2 0.772
Yeast
aging GO:0007568 2 0.682
Worm
cellular macromolecule catabolic process GO:0044265 12 0.498
Human Yeast
proteolysis GO:0006508 38 0.320
Human Yeast
embryo development ending in birth or egg hatching GO:0009792 271 0.272
Worm
signal transduction GO:0007165 455 0.262
regulation of nucleic acid templated transcription GO:1903506 213 0.224
Human
cellular response to dna damage stimulus GO:0006974 24 0.219
Fly
response to stress GO:0006950 263 0.215
Fly
single fertilization GO:0007338 3 0.198
locomotion GO:0040011 313 0.197
Worm
macromolecule catabolic process GO:0009057 15 0.175
Human Yeast
reproduction GO:0000003 40 0.170
Worm
cellular response to stress GO:0033554 62 0.157
Fly
rna biosynthetic process GO:0032774 181 0.135
Human
heterocycle biosynthetic process GO:0018130 215 0.129
Human
positive regulation of cellular process GO:0048522 201 0.121
organic substance catabolic process GO:1901575 28 0.120
Human Yeast
catabolic process GO:0009056 32 0.119
Human Yeast
positive regulation of biological process GO:0048518 253 0.113
Human
nucleobase containing compound biosynthetic process GO:0034654 205 0.110
Human
regulation of transcription dna templated GO:0006355 213 0.100
Human
transcription dna templated GO:0006351 181 0.099
Human
nucleic acid metabolic process GO:0090304 244 0.097
Human
cellular biosynthetic process GO:0044249 286 0.087
Human
single organism organelle organization GO:1902589 199 0.084
response to abiotic stimulus GO:0009628 122 0.082
pronuclear migration GO:0035046 1 0.074
organic cyclic compound biosynthetic process GO:1901362 223 0.069
Human
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.067
Human
organic cyclic compound metabolic process GO:1901360 301 0.064
Human
transcription from rna polymerase ii promoter GO:0006366 80 0.060
protein catabolic process GO:0030163 7 0.060
Human Yeast
rna metabolic process GO:0016070 219 0.058
Human
regulation of gene expression GO:0010468 265 0.058
Human
nucleic acid templated transcription GO:0097659 181 0.057
Human
programmed cell death GO:0012501 119 0.056
biosynthetic process GO:0009058 294 0.056
Human
death GO:0016265 121 0.055
cellular nitrogen compound metabolic process GO:0034641 290 0.055
Human
spindle assembly involved in mitosis GO:0090307 1 0.054
regulation of response to stimulus GO:0048583 269 0.053
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.053
regulation of rna metabolic process GO:0051252 224 0.052
Human
transport GO:0006810 220 0.051
regulation of cellular component organization GO:0051128 86 0.051
regulation of macromolecule biosynthetic process GO:0010556 225 0.050
Human
meiotic cell cycle process GO:1903046 3 0.050
regulation of protein complex assembly GO:0043254 3 0.050
regulation of macromolecule metabolic process GO:0060255 317 0.049
Human
regulation of rna biosynthetic process GO:2001141 213 0.049
Human
cellular macromolecule metabolic process GO:0044260 391 0.049
Human Yeast
regulation of biosynthetic process GO:0009889 250 0.048
Human
fertilization GO:0009566 3 0.047
meiotic nuclear division GO:0007126 4 0.046
gene expression GO:0010467 252 0.045
Human
protein import into nucleus GO:0006606 3 0.045
eye development GO:0001654 277 0.045
regulation of cellular biosynthetic process GO:0031326 245 0.043
Human
nitrogen compound metabolic process GO:0006807 319 0.043
Human
cellular response to external stimulus GO:0071496 2 0.042
regulation of cell communication GO:0010646 232 0.042
cellular protein metabolic process GO:0044267 129 0.041
Human Yeast
negative regulation of biological process GO:0048519 304 0.040
cellular aromatic compound metabolic process GO:0006725 295 0.040
Human
regulation of cellular ketone metabolic process GO:0010565 7 0.040
positive regulation of nucleic acid templated transcription GO:1903508 57 0.039
protein metabolic process GO:0019538 183 0.039
Human Yeast
apoptotic process GO:0006915 116 0.038
nucleobase containing compound metabolic process GO:0006139 274 0.038
Human
positive regulation of rna biosynthetic process GO:1902680 57 0.038
organic substance biosynthetic process GO:1901576 289 0.037
Human
protein complex subunit organization GO:0071822 46 0.037
regulation of signal transduction GO:0009966 225 0.036
aromatic compound biosynthetic process GO:0019438 217 0.036
Human
negative regulation of cellular process GO:0048523 283 0.036
response to external stimulus GO:0009605 264 0.036
positive regulation of cellular component biogenesis GO:0044089 3 0.035
cellular component morphogenesis GO:0032989 336 0.035
cellular response to reactive oxygen species GO:0034614 2 0.035
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.034
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.033
Human
spindle assembly GO:0051225 2 0.033
cellular protein complex assembly GO:0043623 19 0.033
protein complex assembly GO:0006461 30 0.032
cellular ketone metabolic process GO:0042180 11 0.031
organelle organization GO:0006996 227 0.030
macromolecule biosynthetic process GO:0009059 227 0.030
Human
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.030
cellular nitrogen compound biosynthetic process GO:0044271 218 0.029
Human
cellular component assembly GO:0022607 170 0.029
embryonic skeletal system morphogenesis GO:0048704 93 0.029
cell death GO:0008219 121 0.029
rrna catabolic process GO:0016075 1 0.029
meiosis ii GO:0007135 1 0.029
positive regulation of macromolecule metabolic process GO:0010604 93 0.029
peptidyl serine phosphorylation GO:0018105 1 0.028
neuron differentiation GO:0030182 353 0.027
dna biosynthetic process GO:0071897 3 0.027
positive regulation of cell cycle GO:0045787 3 0.027
regulation of establishment of protein localization GO:0070201 4 0.027
chordate embryonic development GO:0043009 271 0.026
vesicle mediated transport GO:0016192 22 0.026
embryonic organ development GO:0048568 381 0.026
positive regulation of cellular biosynthetic process GO:0031328 68 0.025
positive regulation of rna metabolic process GO:0051254 59 0.025
cell motility GO:0048870 244 0.025
camera type eye development GO:0043010 222 0.024
regulation of protein catabolic process GO:0042176 1 0.024
cell projection morphogenesis GO:0048858 244 0.024
notch signaling pathway GO:0007219 35 0.024
regulation of apoptotic process GO:0042981 98 0.023
positive regulation of proteolysis GO:0045862 10 0.023
organelle fission GO:0048285 23 0.023
dna templated transcription initiation GO:0006352 1 0.023
regulation of dna templated transcription elongation GO:0032784 3 0.023
cell surface receptor signaling pathway GO:0007166 325 0.023
regulation of biological quality GO:0065008 263 0.023
dna templated transcription elongation GO:0006354 3 0.022
regulation of cellular metabolic process GO:0031323 320 0.022
Human
mitotic sister chromatid segregation GO:0000070 6 0.022
cell morphogenesis GO:0000902 289 0.022
regulation of cellular amine metabolic process GO:0033238 0 0.022
regulation of meiotic cell cycle GO:0051445 1 0.022
response to chemical GO:0042221 320 0.022
protein localization to nucleus GO:0034504 3 0.021
positive regulation of catabolic process GO:0009896 4 0.021
protein import GO:0017038 3 0.021
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.021
positive regulation of protein complex assembly GO:0031334 2 0.021
establishment of protein localization to organelle GO:0072594 4 0.020
microtubule based process GO:0007017 60 0.020
nuclear migration GO:0007097 3 0.020
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.020
organelle assembly GO:0070925 110 0.020
post embryonic development GO:0009791 7 0.019
Worm
heterocycle metabolic process GO:0046483 290 0.019
Human
protein complex biogenesis GO:0070271 30 0.019
negative regulation of intracellular transport GO:0032387 3 0.019
protein targeting to nucleus GO:0044744 3 0.019
regulation of primary metabolic process GO:0080090 311 0.018
Human
positive regulation of biosynthetic process GO:0009891 68 0.018
organonitrogen compound metabolic process GO:1901564 74 0.018
establishment of localization GO:0051234 244 0.018
cell cycle g2 m phase transition GO:0044839 4 0.018
regulation of cytoplasmic transport GO:1903649 4 0.018
ribonucleoside monophosphate catabolic process GO:0009158 4 0.018
regulation of response to stress GO:0080134 36 0.018
regulation of protein targeting GO:1903533 2 0.018
double strand break repair via homologous recombination GO:0000724 1 0.018
cell proliferation GO:0008283 80 0.018
single organism nuclear import GO:1902593 3 0.017
regulation of nitrogen compound metabolic process GO:0051171 251 0.017
Human
cellular carbohydrate metabolic process GO:0044262 4 0.017
single organism transport GO:0044765 206 0.017
neuron development GO:0048666 262 0.017
purine nucleoside monophosphate catabolic process GO:0009128 4 0.017
regulation of nucleocytoplasmic transport GO:0046822 2 0.017
nucleoside monophosphate catabolic process GO:0009125 4 0.017
positive regulation of transcription dna templated GO:0045893 57 0.017
regulation of cell differentiation GO:0045595 142 0.016
cellular response to nutrient levels GO:0031669 2 0.016
macromolecular complex subunit organization GO:0043933 74 0.016
cellular component biogenesis GO:0044085 178 0.016
response to hydrogen peroxide GO:0042542 3 0.016
nucleocytoplasmic transport GO:0006913 4 0.016
negative regulation of protein transport GO:0051224 3 0.015
cell death in response to oxidative stress GO:0036473 2 0.015
nuclear transport GO:0051169 4 0.015
generation of neurons GO:0048699 385 0.015
regulation of inflammatory response GO:0050727 2 0.015
regulation of developmental process GO:0050793 247 0.015
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.015
cell projection organization GO:0030030 284 0.015
cellular localization GO:0051641 97 0.014
microtubule cytoskeleton organization GO:0000226 33 0.014
cellular protein modification process GO:0006464 100 0.014
small molecule metabolic process GO:0044281 77 0.014
macromolecular complex assembly GO:0065003 35 0.014
microtubule organizing center organization GO:0031023 1 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.014
regulation of binding GO:0051098 3 0.014
cellular amine metabolic process GO:0044106 2 0.014
regulation of programmed cell death GO:0043067 101 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
cell morphogenesis involved in differentiation GO:0000904 195 0.014
immune system process GO:0002376 241 0.014
cell migration GO:0016477 237 0.014
adult behavior GO:0030534 2 0.014
single organism localization GO:1902578 225 0.014
negative regulation of response to stimulus GO:0048585 104 0.014
cellular macromolecule biosynthetic process GO:0034645 224 0.014
Human
regulation of intracellular protein transport GO:0033157 3 0.014
cellular catabolic process GO:0044248 27 0.014
Human Yeast
positive regulation of metabolic process GO:0009893 108 0.014
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.013
amine metabolic process GO:0009308 2 0.013
embryonic cranial skeleton morphogenesis GO:0048701 90 0.013
neuroblast proliferation GO:0007405 2 0.013
stem cell division GO:0017145 1 0.013
protein secretion GO:0009306 1 0.013
regulation of multicellular organismal development GO:2000026 223 0.013
meiotic chromosome segregation GO:0045132 3 0.013
positive regulation of cellular metabolic process GO:0031325 94 0.013
negative regulation of mitosis GO:0045839 3 0.013
regulation of response to oxidative stress GO:1902882 2 0.013
mitotic nuclear division GO:0007067 18 0.013
mitotic cell cycle GO:0000278 64 0.013
meiotic spindle organization GO:0000212 1 0.013
regulation of signaling GO:0023051 235 0.012
cell cycle GO:0007049 93 0.012
nuclear import GO:0051170 3 0.012
positive regulation of gene expression GO:0010628 71 0.012
carboxylic acid metabolic process GO:0019752 22 0.012
maintenance of location GO:0051235 4 0.012
chromosome organization GO:0051276 31 0.012
regulation of proteolysis GO:0030162 24 0.012
centrosome organization GO:0051297 1 0.012
embryonic skeletal system development GO:0048706 97 0.012
regulation of response to external stimulus GO:0032101 31 0.012
protein modification process GO:0036211 100 0.012
positive regulation of nucleoside metabolic process GO:0045979 1 0.012
multi organism process GO:0051704 134 0.011
negative regulation of intracellular protein transport GO:0090317 3 0.011
chemical homeostasis GO:0048878 49 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.011
regulation of protein import into nucleus GO:0042306 2 0.011
chemotaxis GO:0006935 104 0.011
negative regulation of synapse assembly GO:0051964 2 0.011
positive regulation of cellular catabolic process GO:0031331 3 0.011
regulation of metabolic process GO:0019222 359 0.011
Human
cell part morphogenesis GO:0032990 246 0.011
cellular response to starvation GO:0009267 1 0.011
regulation of multicellular organismal process GO:0051239 277 0.011
ncrna catabolic process GO:0034661 1 0.011
ossification GO:0001503 23 0.011
protein modification by small protein removal GO:0070646 1 0.011
canonical wnt signaling pathway GO:0060070 48 0.011
phagocytosis engulfment GO:0006911 1 0.011
aromatic compound catabolic process GO:0019439 15 0.011
sensory organ morphogenesis GO:0090596 200 0.011
autophagy GO:0006914 4 0.011
dna repair GO:0006281 6 0.011
membrane invagination GO:0010324 1 0.011
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.010
cellular macromolecular complex assembly GO:0034622 24 0.010
single organism metabolic process GO:0044710 217 0.010
regulation of chromosome segregation GO:0051983 1 0.010

psma6a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
motor neuron disease DOID:231 0 0.012
central nervous system disease DOID:331 0 0.012
amyotrophic lateral sclerosis DOID:332 0 0.012
disease of anatomical entity DOID:7 0 0.012
neurodegenerative disease DOID:1289 0 0.012
nervous system disease DOID:863 0 0.012