Danio rerio

0 known processes

psma6b

proteasome (prosome, macropain) subunit, alpha type, 6b

(Aliases: zgc:91778)

psma6b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.283
Yeast
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.178
Yeast
proteasomal protein catabolic process GO:0010498 2 0.154
Yeast
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.140
modification dependent macromolecule catabolic process GO:0043632 3 0.130
Yeast
immune system process GO:0002376 241 0.121
cellular macromolecule metabolic process GO:0044260 391 0.111
Yeast
response to other organism GO:0051707 97 0.110
response to external stimulus GO:0009605 264 0.096
cellular nitrogen compound metabolic process GO:0034641 290 0.092
negative regulation of protein phosphorylation GO:0001933 4 0.084
response to biotic stimulus GO:0009607 97 0.084
response to external biotic stimulus GO:0043207 97 0.080
amine metabolic process GO:0009308 2 0.076
cellular amine metabolic process GO:0044106 2 0.074
nuclear transport GO:0051169 4 0.073
regulation of cellular ketone metabolic process GO:0010565 7 0.072
protein metabolic process GO:0019538 183 0.071
Yeast
multi organism process GO:0051704 134 0.070
nucleocytoplasmic transport GO:0006913 4 0.070
cellular amino acid metabolic process GO:0006520 7 0.067
establishment of localization GO:0051234 244 0.066
regulation of cellular amine metabolic process GO:0033238 0 0.065
extrinsic apoptotic signaling pathway GO:0097191 3 0.062
cellular aromatic compound metabolic process GO:0006725 295 0.058
nitrogen compound metabolic process GO:0006807 319 0.056
cellular ketone metabolic process GO:0042180 11 0.055
regulation of cellular metabolic process GO:0031323 320 0.055
signal transduction in absence of ligand GO:0038034 1 0.053
heterocycle metabolic process GO:0046483 290 0.050
regulation of cytokine production GO:0001817 3 0.049
regulation of macromolecule metabolic process GO:0060255 317 0.048
regulation of cellular amino acid metabolic process GO:0006521 0 0.046
cellular protein catabolic process GO:0044257 4 0.046
Yeast
regulation of nucleocytoplasmic transport GO:0046822 2 0.046
stem cell proliferation GO:0072089 4 0.045
regulation of signal transduction GO:0009966 225 0.045
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.044
i kappab kinase nf kappab signaling GO:0007249 4 0.044
immune system development GO:0002520 191 0.044
viral process GO:0016032 1 0.040
multi organism cellular process GO:0044764 2 0.040
proteolysis GO:0006508 38 0.039
Yeast
positive regulation of cellular amine metabolic process GO:0033240 0 0.038
gtp metabolic process GO:0046039 4 0.037
regulation of cell shape GO:0008360 1 0.036
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.036
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.035
positive regulation of biological process GO:0048518 253 0.035
transport GO:0006810 220 0.035
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.035
cellular component disassembly GO:0022411 1 0.034
interspecies interaction between organisms GO:0044419 4 0.033
fertilization GO:0009566 3 0.033
positive regulation of apoptotic signaling pathway GO:2001235 1 0.032
regulation of protein localization to nucleus GO:1900180 2 0.032
modification dependent protein catabolic process GO:0019941 3 0.032
Yeast
response to chemical GO:0042221 320 0.032
single organism transport GO:0044765 206 0.032
organonitrogen compound metabolic process GO:1901564 74 0.031
cellular component biogenesis GO:0044085 178 0.031
positive regulation of cellular component biogenesis GO:0044089 3 0.031
regulation of primary metabolic process GO:0080090 311 0.030
larval development GO:0002164 2 0.030
regulation of cell communication GO:0010646 232 0.030
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.030
negative regulation of biological process GO:0048519 304 0.030
regulation of mrna processing GO:0050684 3 0.029
gene expression GO:0010467 252 0.029
nucleic acid metabolic process GO:0090304 244 0.029
regulation of gene expression GO:0010468 265 0.029
positive regulation of cellular process GO:0048522 201 0.028
regulation of protein complex assembly GO:0043254 3 0.028
regulation of cell activation GO:0050865 1 0.028
organic acid metabolic process GO:0006082 31 0.028
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.028
cognition GO:0050890 1 0.027
phagocytosis GO:0006909 3 0.027
leukocyte mediated cytotoxicity GO:0001909 1 0.027
signal transduction GO:0007165 455 0.027
epithelial cell morphogenesis GO:0003382 2 0.026
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.026
gtp catabolic process GO:0006184 2 0.026
regulation of signaling GO:0023051 235 0.026
negative regulation of cellular process GO:0048523 283 0.026
regulation of cytoplasmic transport GO:1903649 4 0.026
cellular protein metabolic process GO:0044267 129 0.026
Yeast
regulation of multicellular organismal process GO:0051239 277 0.025
centrosome organization GO:0051297 1 0.025
organic substance biosynthetic process GO:1901576 289 0.025
positive regulation of gtp catabolic process GO:0033126 1 0.025
establishment of protein localization to organelle GO:0072594 4 0.025
regulation of multicellular organism growth GO:0040014 4 0.025
regulation of protein transport GO:0051223 3 0.024
regulation of protein import into nucleus GO:0042306 2 0.024
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.024
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.024
hematopoietic or lymphoid organ development GO:0048534 191 0.024
vacuolar transport GO:0007034 2 0.023
immune response GO:0006955 28 0.023
positive regulation of transport GO:0051050 2 0.023
small molecule metabolic process GO:0044281 77 0.023
regulation of synapse assembly GO:0051963 3 0.023
cell death GO:0008219 121 0.022
multicellular organism growth GO:0035264 4 0.022
nucleobase containing compound metabolic process GO:0006139 274 0.022
protein localization to nucleus GO:0034504 3 0.022
positive regulation of endopeptidase activity GO:0010950 10 0.022
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.021
regulation of stem cell differentiation GO:2000736 4 0.021
single fertilization GO:0007338 3 0.021
cytoskeleton dependent cytokinesis GO:0061640 3 0.021
cell surface receptor signaling pathway GO:0007166 325 0.021
sensory organ development GO:0007423 393 0.021
guanosine containing compound catabolic process GO:1901069 2 0.021
hemopoiesis GO:0030097 183 0.020
regulation of gtpase activity GO:0043087 2 0.020
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 10 0.020
positive regulation of leukocyte mediated cytotoxicity GO:0001912 1 0.020
carboxylic acid metabolic process GO:0019752 22 0.020
exocytosis GO:0006887 1 0.020
cellular response to chemical stimulus GO:0070887 157 0.020
single organism localization GO:1902578 225 0.020
small molecule catabolic process GO:0044282 3 0.020
post embryonic organ development GO:0048569 4 0.020
regulation of macromolecule biosynthetic process GO:0010556 225 0.020
guanosine containing compound metabolic process GO:1901068 4 0.020
transcription dna templated GO:0006351 181 0.020
protein targeting to nucleus GO:0044744 3 0.019
peptidyl serine phosphorylation GO:0018105 1 0.019
response to hormone GO:0009725 48 0.019
nuclear import GO:0051170 3 0.019
mononuclear cell proliferation GO:0032943 1 0.019
stem cell maintenance GO:0019827 4 0.019
collagen metabolic process GO:0032963 2 0.019
production of molecular mediator of immune response GO:0002440 2 0.019
organic cyclic compound metabolic process GO:1901360 301 0.019
negative regulation of nuclear division GO:0051784 3 0.019
regulation of endopeptidase activity GO:0052548 23 0.019
synaptic growth at neuromuscular junction GO:0051124 2 0.018
regulation of synapse organization GO:0050807 3 0.018
regulation of mrna splicing via spliceosome GO:0048024 3 0.018
regulation of response to stimulus GO:0048583 269 0.018
ion transport GO:0006811 114 0.018
positive regulation of cytokine production GO:0001819 2 0.018
regulation of chromosome segregation GO:0051983 1 0.018
regulation of protein targeting GO:1903533 2 0.018
regulation of establishment of protein localization GO:0070201 4 0.018
ubiquitin dependent protein catabolic process GO:0006511 3 0.018
Yeast
rna transport GO:0050658 2 0.018
phosphorus metabolic process GO:0006793 109 0.018
cellular response to topologically incorrect protein GO:0035967 2 0.018
oxoacid metabolic process GO:0043436 31 0.018
regulation of rna metabolic process GO:0051252 224 0.017
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.017
carboxylic acid catabolic process GO:0046395 3 0.017
innate immune response GO:0045087 13 0.017
single organism organelle organization GO:1902589 199 0.017
pigment cell differentiation GO:0050931 38 0.017
macromolecule catabolic process GO:0009057 15 0.017
Yeast
lysosomal transport GO:0007041 2 0.017
cellular modified amino acid metabolic process GO:0006575 3 0.017
response to abiotic stimulus GO:0009628 122 0.017
single organism metabolic process GO:0044710 217 0.017
peptidyl serine modification GO:0018209 2 0.016
meiotic chromosome segregation GO:0045132 3 0.016
positive regulation of immune effector process GO:0002699 3 0.016
positive regulation of metabolic process GO:0009893 108 0.016
spindle assembly GO:0051225 2 0.016
regulation of inflammatory response GO:0050727 2 0.016
centrosome cycle GO:0007098 1 0.016
embryo development ending in birth or egg hatching GO:0009792 271 0.016
actin polymerization or depolymerization GO:0008154 2 0.016
regulation of biological quality GO:0065008 263 0.016
single organism membrane fusion GO:0044801 2 0.016
membrane invagination GO:0010324 1 0.016
organic cyclic compound biosynthetic process GO:1901362 223 0.016
mitochondrion organization GO:0007005 4 0.016
peptide metabolic process GO:0006518 1 0.016
intracellular signal transduction GO:0035556 85 0.016
regulation of gtp catabolic process GO:0033124 2 0.015
negative regulation of cellular catabolic process GO:0031330 3 0.015
protein import into nucleus GO:0006606 3 0.015
regulation of molecular function GO:0065009 70 0.015
regulation of protein ubiquitination GO:0031396 3 0.015
protein complex disassembly GO:0043241 1 0.015
protein import GO:0017038 3 0.015
phosphate containing compound metabolic process GO:0006796 108 0.015
regulation of nucleotide catabolic process GO:0030811 2 0.015
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.015
rna metabolic process GO:0016070 219 0.014
positive regulation of cell killing GO:0031343 2 0.014
single organism nuclear import GO:1902593 3 0.014
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.014
regulation of nucleoside metabolic process GO:0009118 2 0.014
negative regulation of signaling GO:0023057 96 0.014
hatching GO:0035188 4 0.014
renal tubule morphogenesis GO:0061333 1 0.014
neuroblast proliferation GO:0007405 2 0.014
regulation of nitrogen compound metabolic process GO:0051171 251 0.014
positive regulation of cytoskeleton organization GO:0051495 3 0.014
regulation of binding GO:0051098 3 0.014
death GO:0016265 121 0.014
cellular response to organic substance GO:0071310 105 0.014
negative regulation of catabolic process GO:0009895 3 0.014
cellular response to lipid GO:0071396 39 0.014
phagocytosis engulfment GO:0006911 1 0.014
membrane fusion GO:0061025 2 0.014
cellular response to starvation GO:0009267 1 0.014
cell projection assembly GO:0030031 64 0.014
lipid storage GO:0019915 1 0.014
cellular localization GO:0051641 97 0.014
regulation of cell cycle GO:0051726 52 0.014
segmentation GO:0035282 97 0.013
regulation of meiotic cell cycle GO:0051445 1 0.013
protein homooligomerization GO:0051260 3 0.013
response to organic substance GO:0010033 153 0.013
defense response to gram positive bacterium GO:0050830 6 0.013
peptidyl lysine acetylation GO:0018394 2 0.013
organelle assembly GO:0070925 110 0.013
microtubule organizing center organization GO:0031023 1 0.013
regulation of intracellular protein transport GO:0033157 3 0.013
protein secretion GO:0009306 1 0.013
defense response GO:0006952 47 0.013
adult behavior GO:0030534 2 0.013
positive regulation of chromosome organization GO:2001252 1 0.013
mitotic dna integrity checkpoint GO:0044774 4 0.013
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.013
positive regulation of gtpase activity GO:0043547 1 0.013
meiotic cell cycle process GO:1903046 3 0.013
negative regulation of synapse assembly GO:0051964 2 0.013
regulation of stem cell proliferation GO:0072091 2 0.013
positive regulation of chromatin modification GO:1903310 1 0.013
aromatic compound biosynthetic process GO:0019438 217 0.013
regulation of purine nucleotide catabolic process GO:0033121 2 0.013
cellular catabolic process GO:0044248 27 0.013
Yeast
fatty acid catabolic process GO:0009062 1 0.012
regulation of cell killing GO:0031341 2 0.012
secondary metabolic process GO:0019748 3 0.012
positive regulation of cell cycle GO:0045787 3 0.012
biosynthetic process GO:0009058 294 0.012
ribonucleoside monophosphate catabolic process GO:0009158 4 0.012
regulation of protein metabolic process GO:0051246 56 0.012
establishment of localization in cell GO:0051649 77 0.012
organelle organization GO:0006996 227 0.012
cellular response to endogenous stimulus GO:0071495 68 0.012
cytokinesis GO:0000910 3 0.012
regulation of cellular protein metabolic process GO:0032268 52 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
response to endogenous stimulus GO:0009719 83 0.012
atp catabolic process GO:0006200 4 0.012
germ line stem cell maintenance GO:0030718 2 0.012
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.012
regulation of synaptic plasticity GO:0048167 1 0.012
aging GO:0007568 2 0.012
positive regulation of nucleotide catabolic process GO:0030813 1 0.012
positive regulation of neuron death GO:1901216 1 0.012
regulation of hematopoietic progenitor cell differentiation GO:1901532 1 0.012
erk1 and erk2 cascade GO:0070371 4 0.012
internal protein amino acid acetylation GO:0006475 2 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.012
regulation of neural precursor cell proliferation GO:2000177 3 0.011
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.011
negative regulation of multi organism process GO:0043901 3 0.011
purine nucleoside monophosphate catabolic process GO:0009128 4 0.011
negative regulation of mitosis GO:0045839 3 0.011
regulation of programmed cell death GO:0043067 101 0.011
cell cycle g1 s phase transition GO:0044843 1 0.011
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.011
cellular response to organic cyclic compound GO:0071407 38 0.011
positive regulation of macromolecule metabolic process GO:0010604 93 0.011
apoptotic process GO:0006915 116 0.011
organism emergence from protective structure GO:0071684 4 0.011
epithelial cell differentiation GO:0030855 116 0.011
organelle fusion GO:0048284 3 0.011
g1 s transition of mitotic cell cycle GO:0000082 1 0.011
glial cell migration GO:0008347 3 0.011
response to drug GO:0042493 3 0.011
cellular response to estradiol stimulus GO:0071392 1 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.011
positive regulation of protein metabolic process GO:0051247 23 0.011
macromolecular complex subunit organization GO:0043933 74 0.011
endoplasmic reticulum unfolded protein response GO:0030968 2 0.011
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.011
vasculature development GO:0001944 278 0.011
mitotic dna damage checkpoint GO:0044773 4 0.011
regulation of metabolic process GO:0019222 359 0.011
macromolecular complex assembly GO:0065003 35 0.011
nephron morphogenesis GO:0072028 2 0.011
negative regulation of cell communication GO:0010648 96 0.011
regulation of apoptotic process GO:0042981 98 0.011
endosomal transport GO:0016197 2 0.011
er nucleus signaling pathway GO:0006984 2 0.010
cellular amide metabolic process GO:0043603 4 0.010
developmental programmed cell death GO:0010623 4 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.010
small gtpase mediated signal transduction GO:0007264 8 0.010
positive regulation of cellular metabolic process GO:0031325 94 0.010
sensory system development GO:0048880 76 0.010
dna templated transcription elongation GO:0006354 3 0.010
tissue remodeling GO:0048771 4 0.010
growth GO:0040007 174 0.010
positive regulation of nucleoside metabolic process GO:0045979 1 0.010
positive regulation of myeloid cell differentiation GO:0045639 2 0.010
response to topologically incorrect protein GO:0035966 2 0.010
regulation of biosynthetic process GO:0009889 250 0.010
regulation of cell death GO:0010941 103 0.010
meiosis i GO:0007127 1 0.010
protein complex localization GO:0031503 1 0.010
internal peptidyl lysine acetylation GO:0018393 2 0.010
neurotransmitter transport GO:0006836 2 0.010
positive regulation of histone modification GO:0031058 1 0.010
regulation of nucleic acid templated transcription GO:1903506 213 0.010
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.010

psma6b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.034
nervous system disease DOID:863 0 0.034
myopathy DOID:423 0 0.021
muscular disease DOID:0080000 0 0.021
musculoskeletal system disease DOID:17 0 0.021
muscle tissue disease DOID:66 0 0.021
heart disease DOID:114 0 0.016
cardiomyopathy DOID:0050700 0 0.016
intrinsic cardiomyopathy DOID:0060036 0 0.016
cardiovascular system disease DOID:1287 0 0.016
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.013