Danio rerio

63 known processes

yes1

v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1

(Aliases: c-yes)

yes1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of signaling GO:0023051 235 0.793
Zebrafish
digestive tract development GO:0048565 265 0.620
regulation of cellular metabolic process GO:0031323 320 0.558
regulation of signal transduction GO:0009966 225 0.518
Zebrafish
erk1 and erk2 cascade GO:0070371 4 0.511
morphogenesis of an epithelium GO:0002009 333 0.496
negative regulation of cellular process GO:0048523 283 0.482
Zebrafish Fly
tube morphogenesis GO:0035239 349 0.459
negative regulation of biological process GO:0048519 304 0.448
Zebrafish Fly
regulation of cellular biosynthetic process GO:0031326 245 0.421
Mouse
multi organism process GO:0051704 134 0.402
Zebrafish Fly
epithelial cell differentiation GO:0030855 116 0.390
Fly
regulation of synapse assembly GO:0051963 3 0.388
Fly
single organism organelle organization GO:1902589 199 0.370
Worm Fly
positive regulation of cellular process GO:0048522 201 0.369
Mouse Fly
cell surface receptor signaling pathway GO:0007166 325 0.363
Zebrafish
regulation of stem cell differentiation GO:2000736 4 0.362
regulation of response to stimulus GO:0048583 269 0.352
Zebrafish
larval development GO:0002164 2 0.346
regulation of mrna processing GO:0050684 3 0.346
gene expression GO:0010467 252 0.338
Mouse
regulation of metabolic process GO:0019222 359 0.337
regulation of cell communication GO:0010646 232 0.322
Zebrafish
cognition GO:0050890 1 0.321
Fly
cellular macromolecule metabolic process GO:0044260 391 0.318
positive regulation of cellular component biogenesis GO:0044089 3 0.318
organic cyclic compound metabolic process GO:1901360 301 0.296
Mouse
protein metabolic process GO:0019538 183 0.296
specification of axis polarity GO:0065001 4 0.293
stem cell maintenance GO:0019827 4 0.291
protein modification process GO:0036211 100 0.287
regulation of erk1 and erk2 cascade GO:0070372 4 0.281
programmed cell death GO:0012501 119 0.274
regulation of cell differentiation GO:0045595 142 0.266
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.265
regulation of epithelial cell proliferation GO:0050678 3 0.258
regulation of intracellular signal transduction GO:1902531 57 0.256
eye development GO:0001654 277 0.255
signal transduction GO:0007165 455 0.248
Zebrafish
response to growth factor GO:0070848 39 0.243
Mouse
cellular protein modification process GO:0006464 100 0.242
anterior posterior pattern specification GO:0009952 152 0.233
Zebrafish
macromolecule biosynthetic process GO:0009059 227 0.233
Mouse
aromatic compound biosynthetic process GO:0019438 217 0.233
Mouse
stem cell proliferation GO:0072089 4 0.231
response to external stimulus GO:0009605 264 0.228
Zebrafish Fly
protein import into nucleus GO:0006606 3 0.223
convergent extension GO:0060026 118 0.217
regulation of multicellular organismal process GO:0051239 277 0.215
Fly
compound eye development GO:0048749 2 0.213
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.208
Mouse
cellular component morphogenesis GO:0032989 336 0.207
Fly
positive regulation of signal transduction GO:0009967 56 0.203
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.201
Fly
regulation of biological quality GO:0065008 263 0.198
Zebrafish Fly
negative regulation of protein kinase activity GO:0006469 4 0.194
rna metabolic process GO:0016070 219 0.192
Mouse
hematopoietic or lymphoid organ development GO:0048534 191 0.185
negative regulation of kinase activity GO:0033673 4 0.185
gastrulation GO:0007369 208 0.183
skeletal system development GO:0001501 181 0.183
multicellular organism growth GO:0035264 4 0.183
digestive tract morphogenesis GO:0048546 231 0.181
cellular response to growth factor stimulus GO:0071363 39 0.180
Mouse
organic substance biosynthetic process GO:1901576 289 0.179
Mouse
biosynthetic process GO:0009058 294 0.178
Mouse
mesenchyme development GO:0060485 127 0.175
cartilage development GO:0051216 96 0.175
brain development GO:0007420 293 0.175
Fly
segmentation GO:0035282 97 0.174
regulation of multicellular organism growth GO:0040014 4 0.173
regulation of developmental process GO:0050793 247 0.172
Fly
positive regulation of catabolic process GO:0009896 4 0.170
ras protein signal transduction GO:0007265 7 0.170
inner ear development GO:0048839 126 0.169
signal transduction by phosphorylation GO:0023014 18 0.169
skeletal system morphogenesis GO:0048705 102 0.168
digestive system development GO:0055123 289 0.167
small gtpase mediated signal transduction GO:0007264 8 0.167
protein import GO:0017038 3 0.166
nucleic acid metabolic process GO:0090304 244 0.166
Mouse
regulation of establishment of protein localization GO:0070201 4 0.166
head development GO:0060322 303 0.165
Fly
embryonic organ morphogenesis GO:0048562 274 0.163
mesenchymal cell differentiation GO:0048762 87 0.161
cellular component movement GO:0006928 335 0.161
Worm Fly
nucleocytoplasmic transport GO:0006913 4 0.160
central nervous system development GO:0007417 387 0.160
Fly
regulation of cellular component organization GO:0051128 86 0.160
Fly
cellular nitrogen compound biosynthetic process GO:0044271 218 0.158
Mouse
canonical wnt signaling pathway GO:0060070 48 0.153
Zebrafish
sensory organ development GO:0007423 393 0.152
regulation of mapk cascade GO:0043408 14 0.148
system process GO:0003008 185 0.148
Fly
localization of cell GO:0051674 244 0.147
Worm
positive regulation of cellular catabolic process GO:0031331 3 0.145
regulation of macromolecule metabolic process GO:0060255 317 0.144
regulation of synapse organization GO:0050807 3 0.143
Fly
regionalization GO:0003002 274 0.142
Zebrafish
mapk cascade GO:0000165 18 0.138
immune system process GO:0002376 241 0.135
regulation of primary metabolic process GO:0080090 311 0.135
generation of neurons GO:0048699 385 0.134
Fly
dorsal ventral pattern formation GO:0009953 125 0.131
regulation of multicellular organismal development GO:2000026 223 0.129
Fly
gtp metabolic process GO:0046039 4 0.129
carbohydrate metabolic process GO:0005975 12 0.129
determination of heart left right asymmetry GO:0061371 117 0.129
determination of left right symmetry GO:0007368 179 0.128
camera type eye development GO:0043010 222 0.126
single organism metabolic process GO:0044710 217 0.126
negative regulation of ras protein signal transduction GO:0046580 1 0.125
protein targeting to nucleus GO:0044744 3 0.124
cell projection organization GO:0030030 284 0.124
Fly
response to stress GO:0006950 263 0.123
Zebrafish
regulation of cell shape GO:0008360 1 0.121
forebrain development GO:0030900 96 0.120
stem cell differentiation GO:0048863 117 0.119
negative regulation of protein phosphorylation GO:0001933 4 0.118
nucleobase containing compound metabolic process GO:0006139 274 0.117
Mouse
organonitrogen compound metabolic process GO:1901564 74 0.116
heterocycle metabolic process GO:0046483 290 0.115
Mouse
negative regulation of signaling GO:0023057 96 0.114
Zebrafish
mesenchymal cell development GO:0014031 78 0.113
regulation of stem cell proliferation GO:0072091 2 0.113
actin filament based process GO:0030029 64 0.111
Fly
embryonic heart tube development GO:0035050 133 0.111
cellular protein metabolic process GO:0044267 129 0.110
phagocytosis GO:0006909 3 0.109
connective tissue development GO:0061448 99 0.109
neurological system process GO:0050877 62 0.109
Fly
specification of symmetry GO:0009799 204 0.108
stem cell development GO:0048864 82 0.107
protein complex localization GO:0031503 1 0.107
stem cell division GO:0017145 1 0.106
heart development GO:0007507 313 0.104
regulation of intracellular protein transport GO:0033157 3 0.104
regulation of protein transport GO:0051223 3 0.104
regulation of cellular response to growth factor stimulus GO:0090287 35 0.103
single organism nuclear import GO:1902593 3 0.103
cell part morphogenesis GO:0032990 246 0.102
Fly
regulation of purine nucleotide catabolic process GO:0033121 2 0.101
positive regulation of cell communication GO:0010647 56 0.099
neuron projection development GO:0031175 180 0.099
Fly
positive regulation of signaling GO:0023056 56 0.098
nuclear import GO:0051170 3 0.098
synaptic vesicle transport GO:0048489 1 0.098
canonical wnt signaling pathway involved in heart development GO:0061316 1 0.097
response to abiotic stimulus GO:0009628 122 0.097
regulation of rna biosynthetic process GO:2001141 213 0.096
Mouse
protein localization to nucleus GO:0034504 3 0.096
heterocycle biosynthetic process GO:0018130 215 0.095
Mouse
negative regulation of signal transduction GO:0009968 94 0.095
Zebrafish
positive regulation of transport GO:0051050 2 0.094
convergent extension involved in gastrulation GO:0060027 71 0.094
regulation of nitrogen compound metabolic process GO:0051171 251 0.093
Mouse
phosphorus metabolic process GO:0006793 109 0.092
intracellular signal transduction GO:0035556 85 0.092
positive regulation of ras protein signal transduction GO:0046579 1 0.092
single organism biosynthetic process GO:0044711 71 0.092
cellular carbohydrate metabolic process GO:0044262 4 0.092
endodermal cell differentiation GO:0035987 19 0.091
Worm
positive regulation of map kinase activity GO:0043406 3 0.090
guanosine containing compound metabolic process GO:1901068 4 0.089
actin polymerization or depolymerization GO:0008154 2 0.088
Fly
establishment of protein localization to organelle GO:0072594 4 0.088
response to other organism GO:0051707 97 0.085
Zebrafish
germ line stem cell division GO:0042078 1 0.085
cell morphogenesis involved in differentiation GO:0000904 195 0.084
Fly
determination of bilateral symmetry GO:0009855 204 0.084
neuroblast differentiation GO:0014016 1 0.083
axon development GO:0061564 166 0.083
Fly
positive regulation of apoptotic signaling pathway GO:2001235 1 0.082
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.082
regulation of protein targeting GO:1903533 2 0.081
immune system development GO:0002520 191 0.081
embryo development ending in birth or egg hatching GO:0009792 271 0.080
Worm
neuron differentiation GO:0030182 353 0.080
Fly
muscle structure development GO:0061061 196 0.079
regulation of oligodendrocyte differentiation GO:0048713 1 0.079
single organism localization GO:1902578 225 0.079
Mouse Worm Fly
epiboly GO:0090504 41 0.079
transcription from rna polymerase ii promoter GO:0006366 80 0.078
Mouse
neuroblast proliferation GO:0007405 2 0.078
positive regulation of biological process GO:0048518 253 0.078
Mouse Fly
regulation of cellular protein metabolic process GO:0032268 52 0.078
small molecule metabolic process GO:0044281 77 0.076
negative regulation of multicellular organismal process GO:0051241 69 0.076
Fly
growth GO:0040007 174 0.076
Zebrafish Fly
locomotion GO:0040011 313 0.076
Worm Fly
regulation of rho protein signal transduction GO:0035023 2 0.075
embryonic organ development GO:0048568 381 0.075
regulation of immune response GO:0050776 14 0.075
axis specification GO:0009798 43 0.075
sensory organ morphogenesis GO:0090596 200 0.075
apoptotic process GO:0006915 116 0.073
cellular ketone metabolic process GO:0042180 11 0.073
exocytosis GO:0006887 1 0.072
epithelial tube morphogenesis GO:0060562 148 0.071
mitotic cell cycle embryonic GO:0045448 2 0.071
striated muscle tissue development GO:0014706 110 0.070
positive regulation of response to stimulus GO:0048584 80 0.069
carbohydrate derivative metabolic process GO:1901135 61 0.069
phosphorylation GO:0016310 69 0.069
regulation of phosphorylation GO:0042325 26 0.069
regulation of protein metabolic process GO:0051246 56 0.068
cellular macromolecule biosynthetic process GO:0034645 224 0.067
Mouse
hemopoiesis GO:0030097 183 0.067
cellular catabolic process GO:0044248 27 0.067
regulation of organ morphogenesis GO:2000027 35 0.067
ubiquitin dependent protein catabolic process GO:0006511 3 0.067
regulation of biosynthetic process GO:0009889 250 0.067
Mouse
wnt signaling pathway GO:0016055 80 0.066
Zebrafish
ameboidal type cell migration GO:0001667 143 0.066
regulation of epithelial to mesenchymal transition GO:0010717 3 0.066
cilium morphogenesis GO:0060271 85 0.066
rna biosynthetic process GO:0032774 181 0.066
Mouse
synaptic transmission GO:0007268 35 0.066
Fly
dorsal convergence GO:0060030 14 0.065
muscle organ development GO:0007517 101 0.065
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.065
cell fate commitment GO:0045165 99 0.064
Worm
regulation of protein catabolic process GO:0042176 1 0.064
positive regulation of cell cycle GO:0045787 3 0.063
establishment of localization in cell GO:0051649 77 0.063
Worm
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.063
Mouse
endoderm development GO:0007492 49 0.063
Worm
negative regulation of map kinase activity GO:0043407 2 0.063
regulation of protein localization to nucleus GO:1900180 2 0.062
somatic stem cell maintenance GO:0035019 1 0.062
regulation of tube size GO:0035150 2 0.062
regulation of cell morphogenesis GO:0022604 42 0.062
tissue regeneration GO:0042246 74 0.061
Zebrafish
regulation of protein ubiquitination GO:0031396 3 0.061
transcription dna templated GO:0006351 181 0.061
Mouse
positive regulation of rna metabolic process GO:0051254 59 0.060
Mouse
spliceosomal complex assembly GO:0000245 1 0.060
regulation of cell projection assembly GO:0060491 4 0.060
nuclear transport GO:0051169 4 0.059
negative regulation of response to stimulus GO:0048585 104 0.059
Zebrafish
i kappab kinase nf kappab signaling GO:0007249 4 0.059
ear development GO:0043583 127 0.059
organelle organization GO:0006996 227 0.059
Worm Fly
cellular component assembly GO:0022607 170 0.059
Fly
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.058
Mouse
embryonic pattern specification GO:0009880 44 0.058
cellular nitrogen compound metabolic process GO:0034641 290 0.058
Mouse
regulation of gtp catabolic process GO:0033124 2 0.057
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.057
regulation of anatomical structure size GO:0090066 33 0.057
Fly
somitogenesis GO:0001756 87 0.057
regulation of apoptotic process GO:0042981 98 0.056
cellular response to extracellular stimulus GO:0031668 2 0.056
positive regulation of chromatin modification GO:1903310 1 0.056
cellular aromatic compound metabolic process GO:0006725 295 0.056
Mouse
regulation of photoreceptor cell differentiation GO:0046532 2 0.055
response to chemical GO:0042221 320 0.055
Mouse Fly
regulation of protein modification process GO:0031399 29 0.055
defense response to other organism GO:0098542 33 0.055
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.055
cell cycle process GO:0022402 53 0.055
Worm
negative regulation of cell communication GO:0010648 96 0.055
Zebrafish
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.055
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.054
negative regulation of metabolic process GO:0009892 86 0.054
carbohydrate biosynthetic process GO:0016051 1 0.054
positive regulation of protein complex assembly GO:0031334 2 0.054
regulation of neural precursor cell proliferation GO:2000177 3 0.054
modification dependent macromolecule catabolic process GO:0043632 3 0.053
heparan sulfate proteoglycan biosynthetic process GO:0015012 5 0.053
wound healing GO:0042060 90 0.053
Zebrafish
pigment cell differentiation GO:0050931 38 0.052
protein trimerization GO:0070206 4 0.052
proximal distal pattern formation GO:0009954 1 0.052
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.052
neuron death GO:0070997 21 0.052
cellular protein catabolic process GO:0044257 4 0.051
synaptic growth at neuromuscular junction GO:0051124 2 0.051
Fly
positive regulation of dna metabolic process GO:0051054 1 0.051
carbohydrate derivative biosynthetic process GO:1901137 43 0.051
regulation of cell development GO:0060284 100 0.051
myeloid cell differentiation GO:0030099 86 0.051
negative regulation of developmental process GO:0051093 65 0.051
Fly
glycoprotein biosynthetic process GO:0009101 21 0.051
negative regulation of macromolecule metabolic process GO:0010605 76 0.050
regulation of nucleotide catabolic process GO:0030811 2 0.050
regulation of blood vessel size GO:0050880 2 0.050
macromolecule modification GO:0043412 111 0.050
negative regulation of cellular metabolic process GO:0031324 77 0.050
positive regulation of jnk cascade GO:0046330 3 0.049
skin development GO:0043588 54 0.049
cell morphogenesis GO:0000902 289 0.049
Fly
glycoprotein metabolic process GO:0009100 23 0.049
maintenance of location GO:0051235 4 0.048
synaptic vesicle localization GO:0097479 1 0.048
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.048
regulation of cytoplasmic transport GO:1903649 4 0.048
response to wounding GO:0009611 116 0.048
Zebrafish
somite development GO:0061053 96 0.048
amine metabolic process GO:0009308 2 0.048
cellular response to stress GO:0033554 62 0.048
regulation of phosphate metabolic process GO:0019220 43 0.048
inorganic ion transmembrane transport GO:0098660 57 0.047
positive regulation of rna biosynthetic process GO:1902680 57 0.047
Mouse
single organismal cell cell adhesion GO:0016337 29 0.047
Fly
lateral inhibition GO:0046331 1 0.047
cell cell signaling GO:0007267 52 0.047
Fly
cell death GO:0008219 121 0.047
epithelial cell morphogenesis GO:0003382 2 0.047
adherens junction organization GO:0034332 4 0.046
Fly
retina development in camera type eye GO:0060041 146 0.046
regulation of protein binding GO:0043393 3 0.045
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.045
interaction with host GO:0051701 4 0.044
multi organism reproductive process GO:0044703 36 0.044
Fly
positive regulation of cellular biosynthetic process GO:0031328 68 0.044
Mouse
regulation of macromolecule biosynthetic process GO:0010556 225 0.044
Mouse
response to transforming growth factor beta GO:0071559 7 0.044
Mouse
nucleobase containing compound biosynthetic process GO:0034654 205 0.044
Mouse
mitotic cell cycle process GO:1903047 48 0.044
Worm
positive regulation of stress activated mapk cascade GO:0032874 3 0.044
positive regulation of metabolic process GO:0009893 108 0.044
Mouse Fly
response to biotic stimulus GO:0009607 97 0.044
Zebrafish
regulation of phosphorus metabolic process GO:0051174 43 0.044
regulation of nucleocytoplasmic transport GO:0046822 2 0.044
cellular response to starvation GO:0009267 1 0.043
positive regulation of notch signaling pathway GO:0045747 3 0.043
extrinsic apoptotic signaling pathway GO:0097191 3 0.043
negative regulation of synapse assembly GO:0051964 2 0.043
Fly
proteasomal protein catabolic process GO:0010498 2 0.042
morphogenesis of an epithelial sheet GO:0002011 49 0.042
regulation of organelle organization GO:0033043 29 0.042
Fly
regulation of nucleic acid templated transcription GO:1903506 213 0.042
Mouse
cytokinetic process GO:0032506 2 0.042
developmental growth GO:0048589 166 0.042
Zebrafish Fly
cell substrate adhesion GO:0031589 4 0.042
cellular response to external stimulus GO:0071496 2 0.042
regulation of rna metabolic process GO:0051252 224 0.042
Mouse
water homeostasis GO:0030104 4 0.042
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.041
Mouse
regulation of protein complex assembly GO:0043254 3 0.041
regulation of wnt signaling pathway GO:0030111 53 0.041
Zebrafish
heart field specification GO:0003128 1 0.041
single organism cell adhesion GO:0098602 29 0.041
Fly
organic substance catabolic process GO:1901575 28 0.040
regulation of embryonic development GO:0045995 47 0.040
negative regulation of catabolic process GO:0009895 3 0.040
embryonic heart tube morphogenesis GO:0003143 108 0.040
negative regulation of mapk cascade GO:0043409 4 0.040
carboxylic acid metabolic process GO:0019752 22 0.040
hindbrain development GO:0030902 91 0.040
heart morphogenesis GO:0003007 156 0.040
mesoderm development GO:0007498 88 0.040
regulation of gene expression GO:0010468 265 0.040
Mouse
sulfur compound biosynthetic process GO:0044272 9 0.040
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.040
regulation of neuron differentiation GO:0045664 56 0.040
cardiac cell fate commitment GO:0060911 1 0.039
negative regulation of protein kinase b signaling GO:0051898 2 0.039
muscle tissue development GO:0060537 110 0.039
germ line stem cell maintenance GO:0030718 2 0.039
cell migration involved in gastrulation GO:0042074 79 0.039
embryonic skeletal system morphogenesis GO:0048704 93 0.039
cellular response to chemical stimulus GO:0070887 157 0.039
Mouse
cytoskeleton organization GO:0007010 96 0.039
Worm Fly
nitrogen compound metabolic process GO:0006807 319 0.039
Mouse
protein acylation GO:0043543 3 0.038
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.038
positive regulation of multicellular organismal process GO:0051240 52 0.038
regulation of programmed cell death GO:0043067 101 0.038
regulation of response to biotic stimulus GO:0002831 2 0.038
regulation of actin cytoskeleton organization GO:0032956 8 0.038
Fly
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 20 0.038
microtubule organizing center organization GO:0031023 1 0.038
positive regulation of nucleic acid templated transcription GO:1903508 57 0.038
Mouse
neurotransmitter secretion GO:0007269 2 0.037
establishment or maintenance of cell polarity GO:0007163 29 0.037
Worm
neural tube patterning GO:0021532 33 0.037
guanosine containing compound catabolic process GO:1901069 2 0.037
dna biosynthetic process GO:0071897 3 0.037
cilium organization GO:0044782 71 0.037
single organism transport GO:0044765 206 0.037
Mouse Fly
cell adhesion GO:0007155 40 0.036
Fly
forebrain cell migration GO:0021885 1 0.036
neurotransmitter transport GO:0006836 2 0.036
neuron development GO:0048666 262 0.036
Fly
neuron projection morphogenesis GO:0048812 161 0.036
Fly
positive regulation of protein metabolic process GO:0051247 23 0.036
Mouse Fly
regulation of cellular amino acid metabolic process GO:0006521 0 0.036
actin cytoskeleton organization GO:0030036 63 0.035
Fly
viral process GO:0016032 1 0.035
sister chromatid cohesion GO:0007062 2 0.035
entrainment of circadian clock GO:0009649 2 0.035
actin filament polymerization GO:0030041 2 0.035
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.034
positive regulation of reproductive process GO:2000243 2 0.034
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.034
cortical cytoskeleton organization GO:0030865 1 0.034
regulation of reproductive process GO:2000241 4 0.034
regulation of neurogenesis GO:0050767 87 0.034
regulation of production of molecular mediator of immune response GO:0002700 1 0.034
desmosome assembly GO:0002159 2 0.034
cellular response to endogenous stimulus GO:0071495 68 0.034
Mouse
positive regulation of cellular metabolic process GO:0031325 94 0.034
Mouse Fly
regulation of cell death GO:0010941 103 0.034
chordate embryonic development GO:0043009 271 0.033
epithelial cell development GO:0002064 42 0.033
Fly
microtubule based process GO:0007017 60 0.033
Worm
peptidyl lysine acetylation GO:0018394 2 0.033
cellular amine metabolic process GO:0044106 2 0.033
regulation of mesenchymal cell proliferation GO:0010464 1 0.033
calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules GO:0016339 2 0.033
protein secretion GO:0009306 1 0.033
lipid storage GO:0019915 1 0.033
cellular response to organic substance GO:0071310 105 0.032
Mouse
regulation of wnt signaling pathway involved in heart development GO:0003307 2 0.032
positive regulation of transcription dna templated GO:0045893 57 0.032
Mouse
cardiocyte differentiation GO:0035051 44 0.032
cell motility GO:0048870 244 0.032
Worm
regulation of glial cell differentiation GO:0045685 4 0.032
macromolecular complex subunit organization GO:0043933 74 0.032
Worm Fly
osteoclast differentiation GO:0030316 1 0.032
cell matrix adhesion GO:0007160 4 0.032
protein polymerization GO:0051258 4 0.031
establishment of cell polarity GO:0030010 18 0.031
Worm
oxoacid metabolic process GO:0043436 31 0.031
regulation of circadian rhythm GO:0042752 4 0.031
endoderm formation GO:0001706 29 0.031
Worm
regulation of cytoskeleton organization GO:0051493 11 0.031
Fly
gtp catabolic process GO:0006184 2 0.031
protein phosphorylation GO:0006468 47 0.031
biological adhesion GO:0022610 40 0.031
Fly
interspecies interaction between organisms GO:0044419 4 0.031
positive regulation of macromolecule metabolic process GO:0010604 93 0.031
Mouse Fly
embryonic skeletal system development GO:0048706 97 0.031
cellular component biogenesis GO:0044085 178 0.031
Fly
defense response GO:0006952 47 0.031
positive regulation of epithelial cell proliferation GO:0050679 1 0.031
pigmentation GO:0043473 85 0.030
positive regulation of protein polymerization GO:0032273 2 0.030
cellular response to nutrient levels GO:0031669 2 0.030
negative chemotaxis GO:0050919 1 0.030
actin filament based movement GO:0030048 1 0.030
camera type eye morphogenesis GO:0048593 108 0.030
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.030
macromolecular complex assembly GO:0065003 35 0.029
embryonic limb morphogenesis GO:0030326 2 0.029
regulation of transport GO:0051049 45 0.029
keratinocyte differentiation GO:0030216 0 0.029
positive regulation of gtpase activity GO:0043547 1 0.029
establishment of epithelial cell polarity GO:0090162 2 0.029
response to external biotic stimulus GO:0043207 97 0.029
Zebrafish
energy reserve metabolic process GO:0006112 2 0.029
regulation of actin filament based process GO:0032970 9 0.029
Fly
negative regulation of rna metabolic process GO:0051253 48 0.029
regulation of developmental growth GO:0048638 38 0.029
Fly
positive regulation of synapse assembly GO:0051965 1 0.028
glycosylation GO:0070085 11 0.028
urogenital system development GO:0001655 97 0.028
organic cyclic compound biosynthetic process GO:1901362 223 0.028
Mouse
cell projection morphogenesis GO:0048858 244 0.028
Fly
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.028
regulation of cell proliferation GO:0042127 37 0.028
anatomical structure arrangement GO:0048532 2 0.028
regulation of carbohydrate metabolic process GO:0006109 4 0.028
bmp signaling pathway GO:0030509 52 0.028
protein stabilization GO:0050821 2 0.028
negative regulation of protein transport GO:0051224 3 0.028
nucleic acid templated transcription GO:0097659 181 0.028
Mouse
regulation of cell proliferation involved in heart morphogenesis GO:2000136 2 0.028
regulation of epidermis development GO:0045682 2 0.028
meiotic spindle organization GO:0000212 1 0.028
modification dependent protein catabolic process GO:0019941 3 0.028
negative regulation of catalytic activity GO:0043086 21 0.028
protein polyubiquitination GO:0000209 4 0.027
establishment of endothelial barrier GO:0061028 3 0.027
establishment of localization GO:0051234 244 0.027
Mouse Worm Fly
calcium ion import GO:0070509 4 0.027
striated muscle cell differentiation GO:0051146 129 0.027
phagocytosis engulfment GO:0006911 1 0.027
cell migration GO:0016477 237 0.027
Worm

yes1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.269
colon carcinoma DOID:1520 0 0.117
large intestine cancer DOID:5672 0 0.117
colon cancer DOID:219 0 0.117
gastrointestinal system cancer DOID:3119 0 0.117
intestinal cancer DOID:10155 0 0.117
cancer DOID:162 0 0.117
disease of cellular proliferation DOID:14566 0 0.117
organ system cancer DOID:0050686 0 0.117
colorectal cancer DOID:9256 0 0.117
nervous system disease DOID:863 0 0.102
musculoskeletal system disease DOID:17 0 0.092
sensory system disease DOID:0050155 0 0.038
eye and adnexa disease DOID:1492 0 0.038
myopathy DOID:423 0 0.032
muscular disease DOID:0080000 0 0.032
muscle tissue disease DOID:66 0 0.032
disease of metabolism DOID:0014667 0 0.030