Danio rerio

0 known processes

polr3e

polymerase (RNA) III (DNA directed) polypeptide E

(Aliases: wu:fs42e03,wu:fb12d10,Sin,zgc:55592)

polr3e biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
immune system development GO:0002520 191 0.178
regulation of metabolic process GO:0019222 359 0.156
Worm
cellular macromolecule metabolic process GO:0044260 391 0.101
organic substance biosynthetic process GO:1901576 289 0.094
aging GO:0007568 2 0.083
regulation of multicellular organism growth GO:0040014 4 0.077
hematopoietic or lymphoid organ development GO:0048534 191 0.069
cell surface receptor signaling pathway GO:0007166 325 0.068
nucleobase containing compound biosynthetic process GO:0034654 205 0.064
positive regulation of cellular component biogenesis GO:0044089 3 0.058
cellular aromatic compound metabolic process GO:0006725 295 0.055
maturation of ssu rrna GO:0030490 1 0.054
gene expression GO:0010467 252 0.053
Worm
rna metabolic process GO:0016070 219 0.052
organic cyclic compound metabolic process GO:1901360 301 0.052
rna biosynthetic process GO:0032774 181 0.052
guanosine containing compound metabolic process GO:1901068 4 0.052
adult behavior GO:0030534 2 0.050
aromatic compound biosynthetic process GO:0019438 217 0.049
gtp metabolic process GO:0046039 4 0.049
cellular nitrogen compound metabolic process GO:0034641 290 0.049
macromolecule biosynthetic process GO:0009059 227 0.048
lipid storage GO:0019915 1 0.048
localization of cell GO:0051674 244 0.045
regulation of primary metabolic process GO:0080090 311 0.045
ribosomal small subunit biogenesis GO:0042274 2 0.043
protein acetylation GO:0006473 2 0.042
single organism metabolic process GO:0044710 217 0.041
organic cyclic compound biosynthetic process GO:1901362 223 0.041
hemopoiesis GO:0030097 183 0.041
gtp catabolic process GO:0006184 2 0.041
multicellular organism growth GO:0035264 4 0.041
nucleic acid metabolic process GO:0090304 244 0.037
small molecule metabolic process GO:0044281 77 0.037
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.037
cellular macromolecule biosynthetic process GO:0034645 224 0.036
biosynthetic process GO:0009058 294 0.036
heterocycle metabolic process GO:0046483 290 0.036
regulation of nervous system development GO:0051960 90 0.034
nucleic acid templated transcription GO:0097659 181 0.034
positive regulation of transport GO:0051050 2 0.032
cellular response to nutrient levels GO:0031669 2 0.031
cellular amine metabolic process GO:0044106 2 0.031
nucleobase containing compound metabolic process GO:0006139 274 0.031
internal protein amino acid acetylation GO:0006475 2 0.030
heterocycle biosynthetic process GO:0018130 215 0.030
amine metabolic process GO:0009308 2 0.030
cellular component movement GO:0006928 335 0.030
cell part morphogenesis GO:0032990 246 0.030
maintenance of location GO:0051235 4 0.030
regulation of multicellular organismal development GO:2000026 223 0.029
vasculature development GO:0001944 278 0.029
cellular biosynthetic process GO:0044249 286 0.029
guanosine containing compound catabolic process GO:1901069 2 0.029
regulation of gene expression GO:0010468 265 0.028
Worm
regulation of cellular biosynthetic process GO:0031326 245 0.028
cellular amino acid metabolic process GO:0006520 7 0.028
synaptic growth at neuromuscular junction GO:0051124 2 0.028
negative regulation of protein kinase activity GO:0006469 4 0.028
signal transduction GO:0007165 455 0.028
cellular response to starvation GO:0009267 1 0.028
negative regulation of protein phosphorylation GO:0001933 4 0.028
central nervous system development GO:0007417 387 0.027
cellular response to external stimulus GO:0071496 2 0.027
response to chemical GO:0042221 320 0.027
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.027
head development GO:0060322 303 0.027
cell projection morphogenesis GO:0048858 244 0.027
regulation of cellular metabolic process GO:0031323 320 0.026
negative regulation of cell communication GO:0010648 96 0.026
system process GO:0003008 185 0.026
embryonic organ development GO:0048568 381 0.026
digestive tract development GO:0048565 265 0.026
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000462 1 0.026
stem cell differentiation GO:0048863 117 0.026
nuclear import GO:0051170 3 0.026
protein acylation GO:0043543 3 0.025
protein modification process GO:0036211 100 0.025
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.025
regulation of establishment of protein localization GO:0070201 4 0.025
morphogenesis of an epithelium GO:0002009 333 0.025
regulation of nucleic acid templated transcription GO:1903506 213 0.025
ncrna metabolic process GO:0034660 12 0.024
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.024
stem cell maintenance GO:0019827 4 0.024
cell motility GO:0048870 244 0.024
ribosome assembly GO:0042255 1 0.024
cellular response to extracellular stimulus GO:0031668 2 0.024
regulation of response to stimulus GO:0048583 269 0.024
regulation of cellular ketone metabolic process GO:0010565 7 0.024
macromolecule modification GO:0043412 111 0.023
blood vessel morphogenesis GO:0048514 216 0.023
negative regulation of signaling GO:0023057 96 0.023
regulation of cellular amine metabolic process GO:0033238 0 0.023
immune system process GO:0002376 241 0.022
cell morphogenesis GO:0000902 289 0.022
cellular modified amino acid metabolic process GO:0006575 3 0.022
transcription dna templated GO:0006351 181 0.022
lateral inhibition GO:0046331 1 0.022
regulation of neuron differentiation GO:0045664 56 0.022
nitrogen compound metabolic process GO:0006807 319 0.022
regulation of macromolecule metabolic process GO:0060255 317 0.022
Worm
protein metabolic process GO:0019538 183 0.021
rna modification GO:0009451 2 0.021
mesenchyme development GO:0060485 127 0.021
positive regulation of cellular catabolic process GO:0031331 3 0.021
stem cell proliferation GO:0072089 4 0.021
regulation of cellular amino acid metabolic process GO:0006521 0 0.021
regulation of protein targeting GO:1903533 2 0.021
nucleocytoplasmic transport GO:0006913 4 0.021
regulation of cell communication GO:0010646 232 0.020
response to drug GO:0042493 3 0.020
cell migration GO:0016477 237 0.020
regulation of rna biosynthetic process GO:2001141 213 0.020
peptidyl lysine acetylation GO:0018394 2 0.020
regulation of biosynthetic process GO:0009889 250 0.019
cognition GO:0050890 1 0.019
reproductive process GO:0022414 40 0.019
larval development GO:0002164 2 0.019
Worm
regulation of response to extracellular stimulus GO:0032104 1 0.019
regulation of signal transduction GO:0009966 225 0.019
multi organism process GO:0051704 134 0.019
protein import GO:0017038 3 0.018
determination of bilateral symmetry GO:0009855 204 0.018
negative regulation of signal transduction GO:0009968 94 0.018
enzyme linked receptor protein signaling pathway GO:0007167 106 0.018
cellular response to chemical stimulus GO:0070887 157 0.018
positive regulation of stem cell proliferation GO:2000648 1 0.018
extrinsic apoptotic signaling pathway GO:0097191 3 0.018
specification of symmetry GO:0009799 204 0.018
organic acid metabolic process GO:0006082 31 0.018
protein import into nucleus GO:0006606 3 0.018
growth GO:0040007 174 0.018
regulation of developmental process GO:0050793 247 0.018
cell proliferation GO:0008283 80 0.017
female sex differentiation GO:0046660 4 0.017
translational initiation GO:0006413 3 0.017
phagocytosis GO:0006909 3 0.017
phosphate containing compound metabolic process GO:0006796 108 0.017
regulation of skeletal muscle tissue development GO:0048641 4 0.017
regulation of jak stat cascade GO:0046425 3 0.017
regulation of macromolecule biosynthetic process GO:0010556 225 0.017
development of primary female sexual characteristics GO:0046545 4 0.017
organonitrogen compound metabolic process GO:1901564 74 0.017
regulation of cell development GO:0060284 100 0.017
response to hexose GO:0009746 3 0.017
response to carbohydrate GO:0009743 3 0.017
regulation of cell differentiation GO:0045595 142 0.016
regulation of protein ubiquitination GO:0031396 3 0.016
carboxylic acid metabolic process GO:0019752 22 0.016
negative regulation of macromolecule metabolic process GO:0010605 76 0.016
Worm
cellular component morphogenesis GO:0032989 336 0.016
regulation of multicellular organismal process GO:0051239 277 0.016
cellular protein modification process GO:0006464 100 0.016
ncrna processing GO:0034470 8 0.016
regulation of intracellular protein transport GO:0033157 3 0.016
regulation of protein transport GO:0051223 3 0.016
negative regulation of kinase activity GO:0033673 4 0.016
tube morphogenesis GO:0035239 349 0.015
internal peptidyl lysine acetylation GO:0018393 2 0.015
negative regulation of cellular process GO:0048523 283 0.015
positive regulation of catabolic process GO:0009896 4 0.015
leukocyte proliferation GO:0070661 1 0.015
nucleoside monophosphate catabolic process GO:0009125 4 0.015
developmental growth GO:0048589 166 0.015
autophagy GO:0006914 4 0.015
regulation of protein localization to nucleus GO:1900180 2 0.015
response to corticosteroid GO:0031960 1 0.014
cellular response to oxygen levels GO:0071453 1 0.014
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.014
regulation of neurotransmitter transport GO:0051588 1 0.014
tissue remodeling GO:0048771 4 0.014
cell projection organization GO:0030030 284 0.014
response to glucose GO:0009749 3 0.014
blood vessel development GO:0001568 246 0.014
regulation of response to nutrient levels GO:0032107 1 0.014
regulation of sequestering of calcium ion GO:0051282 4 0.014
generation of neurons GO:0048699 385 0.014
regulation of cell activation GO:0050865 1 0.014
cellular ketone metabolic process GO:0042180 11 0.014
gastrulation GO:0007369 208 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
cellular nitrogen compound biosynthetic process GO:0044271 218 0.014
epithelial tube morphogenesis GO:0060562 148 0.014
negative regulation of response to stimulus GO:0048585 104 0.014
regulation of cytoplasmic transport GO:1903649 4 0.014
digestive system development GO:0055123 289 0.014
neuron differentiation GO:0030182 353 0.014
regulation of neuron projection development GO:0010975 40 0.014
response to glucocorticoid GO:0051384 1 0.014
mesenchymal cell differentiation GO:0048762 87 0.014
female gonad development GO:0008585 4 0.014
regulation of catalytic activity GO:0050790 55 0.014
regionalization GO:0003002 274 0.014
sequestering of metal ion GO:0051238 3 0.014
negative regulation of mapk cascade GO:0043409 4 0.014
mesenchymal cell development GO:0014031 78 0.014
neuron development GO:0048666 262 0.014
eye development GO:0001654 277 0.013
ras protein signal transduction GO:0007265 7 0.013
lymphocyte proliferation GO:0046651 1 0.013
single organism nuclear import GO:1902593 3 0.013
regulation of nitrogen compound metabolic process GO:0051171 251 0.013
oxoacid metabolic process GO:0043436 31 0.013
regulation of signaling GO:0023051 235 0.013
release of sequestered calcium ion into cytosol GO:0051209 3 0.013
urogenital system development GO:0001655 97 0.013
ameboidal type cell migration GO:0001667 143 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.013
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.013
regulation of glucose transport GO:0010827 1 0.013
camera type eye development GO:0043010 222 0.013
regulation of synapse organization GO:0050807 3 0.013
cellular response to xenobiotic stimulus GO:0071466 35 0.012
sensory organ development GO:0007423 393 0.012
spindle assembly GO:0051225 2 0.012
ovulation cycle process GO:0022602 2 0.012
branching morphogenesis of a nerve GO:0048755 4 0.012
response to monosaccharide GO:0034284 3 0.012
protein targeting to nucleus GO:0044744 3 0.012
angiogenesis GO:0001525 158 0.012
regulation of glucose import GO:0046324 1 0.012
determination of left right symmetry GO:0007368 179 0.012
mononuclear cell proliferation GO:0032943 1 0.012
neuron projection development GO:0031175 180 0.012
behavior GO:0007610 74 0.012
brain development GO:0007420 293 0.012
regulation of cell projection organization GO:0031344 44 0.012
regulation of translational initiation GO:0006446 1 0.012
odontogenesis of dentin containing tooth GO:0042475 1 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.012
regulation of canonical wnt signaling pathway GO:0060828 34 0.011
regulation of mitochondrion organization GO:0010821 1 0.011
negative regulation of secretion GO:0051048 2 0.011
retina development in camera type eye GO:0060041 146 0.011
regulation of cell shape GO:0008360 1 0.011
sister chromatid cohesion GO:0007062 2 0.011
regulation of protein import into nucleus GO:0042306 2 0.011
establishment of protein localization to organelle GO:0072594 4 0.011
positive regulation of protein complex assembly GO:0031334 2 0.011
regulation of autophagy GO:0010506 3 0.011
embryonic hemopoiesis GO:0035162 53 0.011
b cell activation GO:0042113 2 0.011
negative regulation of biological process GO:0048519 304 0.011
Worm
homeostatic process GO:0042592 142 0.011
response to hormone GO:0009725 48 0.011
negative regulation of phosphate metabolic process GO:0045936 13 0.011
protein localization to nucleus GO:0034504 3 0.011
organelle localization GO:0051640 49 0.011
regulation of metal ion transport GO:0010959 4 0.011
sequestering of calcium ion GO:0051208 3 0.011
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.011
response to bacterium GO:0009617 58 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.011
regulation of protein complex assembly GO:0043254 3 0.010
convergent extension GO:0060026 118 0.010
response to xenobiotic stimulus GO:0009410 45 0.010
pyrimidine containing compound metabolic process GO:0072527 3 0.010
developmental cell growth GO:0048588 52 0.010
protein stabilization GO:0050821 2 0.010
negative regulation of cellular metabolic process GO:0031324 77 0.010
actin polymerization or depolymerization GO:0008154 2 0.010
negative regulation of sequestering of calcium ion GO:0051283 4 0.010
positive regulation of muscle organ development GO:0048636 1 0.010
regulation of protein modification process GO:0031399 29 0.010
regulation of purine nucleotide catabolic process GO:0033121 2 0.010
calcium ion transport into cytosol GO:0060402 3 0.010
ribonucleoside monophosphate catabolic process GO:0009158 4 0.010

polr3e disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.026
disease of cellular proliferation DOID:14566 0 0.026
organ system cancer DOID:0050686 0 0.026
disease of anatomical entity DOID:7 0 0.020
sensory system disease DOID:0050155 0 0.018
eye and adnexa disease DOID:1492 0 0.018
nervous system disease DOID:863 0 0.018
disease of metabolism DOID:0014667 0 0.011