Danio rerio

0 known processes

ggcx

gamma-glutamyl carboxylase

(Aliases: MGC158736,cb751,si:ch1073-230p18.3,zgc:158736)

ggcx biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.234
positive regulation of cellular component biogenesis GO:0044089 3 0.232
aging GO:0007568 2 0.101
carboxylic acid catabolic process GO:0046395 3 0.097
cellular modified amino acid metabolic process GO:0006575 3 0.096
autophagy GO:0006914 4 0.093
response to drug GO:0042493 3 0.091
positive regulation of biological process GO:0048518 253 0.079
golgi vesicle transport GO:0048193 3 0.068
oxoacid metabolic process GO:0043436 31 0.068
locomotion GO:0040011 313 0.065
alpha amino acid metabolic process GO:1901605 3 0.062
cellular component morphogenesis GO:0032989 336 0.060
organic acid catabolic process GO:0016054 3 0.058
organic acid metabolic process GO:0006082 31 0.058
response to external stimulus GO:0009605 264 0.055
lipid storage GO:0019915 1 0.053
er to golgi vesicle mediated transport GO:0006888 1 0.053
maintenance of location GO:0051235 4 0.051
small molecule catabolic process GO:0044282 3 0.051
cell migration GO:0016477 237 0.049
generation of neurons GO:0048699 385 0.048
axon development GO:0061564 166 0.048
multicellular organismal metabolic process GO:0044236 2 0.046
lipid oxidation GO:0034440 1 0.045
response to organic cyclic compound GO:0014070 51 0.045
fatty acid oxidation GO:0019395 1 0.044
single organism metabolic process GO:0044710 217 0.044
cellular amino acid metabolic process GO:0006520 7 0.040
positive regulation of catabolic process GO:0009896 4 0.040
cell morphogenesis GO:0000902 289 0.039
phagocytosis GO:0006909 3 0.039
regulation of protein targeting GO:1903533 2 0.038
regulation of biological quality GO:0065008 263 0.037
regulation of protein polymerization GO:0032271 2 0.037
regulation of cell projection assembly GO:0060491 4 0.037
small molecule metabolic process GO:0044281 77 0.037
regulation of cell shape GO:0008360 1 0.037
embryo development ending in birth or egg hatching GO:0009792 271 0.037
organonitrogen compound metabolic process GO:1901564 74 0.036
regulation of neuron differentiation GO:0045664 56 0.036
digestive system development GO:0055123 289 0.035
single organism transport GO:0044765 206 0.035
positive regulation of transport GO:0051050 2 0.035
extrinsic apoptotic signaling pathway GO:0097191 3 0.035
regulation of metabolic process GO:0019222 359 0.035
nucleic acid metabolic process GO:0090304 244 0.034
regulation of filopodium assembly GO:0051489 2 0.034
adult behavior GO:0030534 2 0.034
cellular amine metabolic process GO:0044106 2 0.033
positive regulation of cellular catabolic process GO:0031331 3 0.033
regulation of response to stimulus GO:0048583 269 0.033
regulation of apoptotic process GO:0042981 98 0.033
fatty acid beta oxidation GO:0006635 1 0.032
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.032
regulation of establishment of protein localization GO:0070201 4 0.031
carboxylic acid metabolic process GO:0019752 22 0.031
regulation of cellular amine metabolic process GO:0033238 0 0.031
regulation of protein complex assembly GO:0043254 3 0.031
regulation of cell projection organization GO:0031344 44 0.031
regulation of neurogenesis GO:0050767 87 0.030
xenobiotic metabolic process GO:0006805 4 0.030
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.030
protein polymerization GO:0051258 4 0.030
collagen metabolic process GO:0032963 2 0.030
single organism organelle organization GO:1902589 199 0.030
regulation of cellular amino acid metabolic process GO:0006521 0 0.029
cellular component movement GO:0006928 335 0.029
morphogenesis of an epithelium GO:0002009 333 0.029
organic cyclic compound metabolic process GO:1901360 301 0.029
negative regulation of cellular process GO:0048523 283 0.028
multicellular organismal macromolecule metabolic process GO:0044259 2 0.028
regulation of protein transport GO:0051223 3 0.028
nitrogen compound metabolic process GO:0006807 319 0.028
cytoskeleton organization GO:0007010 96 0.028
cellular response to nutrient levels GO:0031669 2 0.028
neuron differentiation GO:0030182 353 0.027
positive regulation of glucose import GO:0046326 1 0.027
regulation of dendrite development GO:0050773 3 0.026
cellular ketone metabolic process GO:0042180 11 0.025
amine metabolic process GO:0009308 2 0.025
sprouting angiogenesis GO:0002040 53 0.024
lipid metabolic process GO:0006629 52 0.024
positive regulation of map kinase activity GO:0043406 3 0.024
gtp catabolic process GO:0006184 2 0.024
cellular macromolecule metabolic process GO:0044260 391 0.024
actin filament based process GO:0030029 64 0.023
cell surface receptor signaling pathway GO:0007166 325 0.023
negative regulation of protein phosphorylation GO:0001933 4 0.023
regulation of glucose transport GO:0010827 1 0.023
signal transduction GO:0007165 455 0.023
regulation of anatomical structure morphogenesis GO:0022603 130 0.023
cellular nitrogen compound metabolic process GO:0034641 290 0.023
cell projection organization GO:0030030 284 0.023
gtp metabolic process GO:0046039 4 0.023
regulation of cellular metabolic process GO:0031323 320 0.023
positive regulation of protein complex assembly GO:0031334 2 0.023
organelle organization GO:0006996 227 0.023
positive regulation of cellular amine metabolic process GO:0033240 0 0.022
regulation of metal ion transport GO:0010959 4 0.022
negative regulation of biological process GO:0048519 304 0.022
establishment of protein localization to organelle GO:0072594 4 0.022
cellular amino acid biosynthetic process GO:0008652 2 0.022
single organism localization GO:1902578 225 0.022
cell part morphogenesis GO:0032990 246 0.022
establishment of localization in cell GO:0051649 77 0.022
regulation of multicellular organism growth GO:0040014 4 0.021
establishment of localization GO:0051234 244 0.021
neuron development GO:0048666 262 0.021
response to nutrient GO:0007584 3 0.021
vasculature development GO:0001944 278 0.021
positive regulation of cytoskeleton organization GO:0051495 3 0.021
cell projection morphogenesis GO:0048858 244 0.021
cellular carbohydrate metabolic process GO:0044262 4 0.021
regulation of organelle assembly GO:1902115 4 0.020
stem cell maintenance GO:0019827 4 0.020
biosynthetic process GO:0009058 294 0.020
organic substance biosynthetic process GO:1901576 289 0.020
cell motility GO:0048870 244 0.020
stem cell development GO:0048864 82 0.020
central nervous system development GO:0007417 387 0.020
glucose import GO:0046323 2 0.020
nucleobase containing compound metabolic process GO:0006139 274 0.020
protein localization to plasma membrane GO:0072659 1 0.020
regulation of hormone secretion GO:0046883 2 0.020
regulation of intracellular protein transport GO:0033157 3 0.019
positive regulation of gtp catabolic process GO:0033126 1 0.019
transport GO:0006810 220 0.019
regulation of cellular ketone metabolic process GO:0010565 7 0.019
heterocycle metabolic process GO:0046483 290 0.019
neuron projection development GO:0031175 180 0.019
nuclear transport GO:0051169 4 0.019
regulation of cell substrate adhesion GO:0010810 1 0.018
regulation of glucose import GO:0046324 1 0.018
single organism biosynthetic process GO:0044711 71 0.018
head development GO:0060322 303 0.018
phosphatidylinositol mediated signaling GO:0048015 2 0.018
regulation of blood vessel size GO:0050880 2 0.018
regulation of nucleotide catabolic process GO:0030811 2 0.018
chemosensory behavior GO:0007635 1 0.018
regulation of signaling GO:0023051 235 0.017
protein import GO:0017038 3 0.017
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.017
fatty acid catabolic process GO:0009062 1 0.017
guanosine containing compound metabolic process GO:1901068 4 0.017
collagen biosynthetic process GO:0032964 2 0.017
cell morphogenesis involved in differentiation GO:0000904 195 0.017
membrane invagination GO:0010324 1 0.017
anion transport GO:0006820 38 0.017
response to vitamin GO:0033273 3 0.017
ion transport GO:0006811 114 0.017
actin polymerization or depolymerization GO:0008154 2 0.016
regulation of gtpase activity GO:0043087 2 0.016
endomembrane system organization GO:0010256 13 0.016
monocarboxylic acid catabolic process GO:0072329 3 0.016
regulation of rna metabolic process GO:0051252 224 0.016
regulation of nucleocytoplasmic transport GO:0046822 2 0.016
negative regulation of rna splicing GO:0033119 1 0.016
nitric oxide metabolic process GO:0046209 2 0.016
response to carbohydrate GO:0009743 3 0.016
regulation of gtp catabolic process GO:0033124 2 0.016
response to hexose GO:0009746 3 0.016
protein metabolic process GO:0019538 183 0.016
mesenchyme development GO:0060485 127 0.016
cellular response to starvation GO:0009267 1 0.015
stem cell proliferation GO:0072089 4 0.015
guanosine containing compound catabolic process GO:1901069 2 0.015
phosphorus metabolic process GO:0006793 109 0.015
response to monosaccharide GO:0034284 3 0.015
regulation of synapse organization GO:0050807 3 0.015
nuclear import GO:0051170 3 0.015
brain development GO:0007420 293 0.015
regulation of reproductive process GO:2000241 4 0.015
death GO:0016265 121 0.015
regulation of protein localization to nucleus GO:1900180 2 0.015
positive regulation of cellular metabolic process GO:0031325 94 0.014
cell substrate adhesion GO:0031589 4 0.014
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.014
glucose homeostasis GO:0042593 1 0.014
muscle structure development GO:0061061 196 0.014
regulation of cytoplasmic transport GO:1903649 4 0.014
muscle organ development GO:0007517 101 0.014
regulation of localization GO:0032879 104 0.014
cell substrate junction assembly GO:0007044 2 0.014
regulation of nervous system development GO:0051960 90 0.014
negative regulation of ras protein signal transduction GO:0046580 1 0.014
nucleic acid templated transcription GO:0097659 181 0.014
regulation of synapse assembly GO:0051963 3 0.014
regulation of cell migration involved in sprouting angiogenesis GO:0090049 3 0.014
regulation of epithelial cell proliferation GO:0050678 3 0.014
cellular localization GO:0051641 97 0.014
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.014
regulation of carbohydrate metabolic process GO:0006109 4 0.014
oxidation reduction process GO:0055114 41 0.014
response to chemical GO:0042221 320 0.014
positive regulation of nucleotide catabolic process GO:0030813 1 0.014
nucleobase containing compound transport GO:0015931 2 0.014
actin cytoskeleton organization GO:0030036 63 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.014
multicellular organism growth GO:0035264 4 0.014
erk1 and erk2 cascade GO:0070371 4 0.013
phagocytosis engulfment GO:0006911 1 0.013
regulation of nitrogen compound metabolic process GO:0051171 251 0.013
negative regulation of dna metabolic process GO:0051053 4 0.013
cellular response to extracellular stimulus GO:0031668 2 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.013
catabolic process GO:0009056 32 0.013
rna localization GO:0006403 4 0.013
internal peptidyl lysine acetylation GO:0018393 2 0.013
negative regulation of protein kinase activity GO:0006469 4 0.013
long chain fatty acid metabolic process GO:0001676 1 0.013
nucleocytoplasmic transport GO:0006913 4 0.013
protein acetylation GO:0006473 2 0.013
positive regulation of reproductive process GO:2000243 2 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.013
cognition GO:0050890 1 0.013
ph reduction GO:0045851 1 0.013
positive regulation of nucleoside metabolic process GO:0045979 1 0.013
regulation of developmental process GO:0050793 247 0.013
striated muscle cell differentiation GO:0051146 129 0.013
positive regulation of cellular process GO:0048522 201 0.013
cell matrix adhesion GO:0007160 4 0.013
multi organism process GO:0051704 134 0.013
regulation of cellular component organization GO:0051128 86 0.012
immune system process GO:0002376 241 0.012
positive regulation of gtpase activity GO:0043547 1 0.012
regulation of molecular function GO:0065009 70 0.012
regulation of nucleoside metabolic process GO:0009118 2 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.012
nucleic acid transport GO:0050657 2 0.012
axonogenesis GO:0007409 152 0.012
regulation of protein catabolic process GO:0042176 1 0.012
organic acid transport GO:0015849 9 0.012
regulation of purine nucleotide catabolic process GO:0033121 2 0.012
apoptotic process GO:0006915 116 0.012
sensory perception of chemical stimulus GO:0007606 3 0.012
response to glucose GO:0009749 3 0.012
cellular lipid catabolic process GO:0044242 3 0.012
regulation of cell activation GO:0050865 1 0.012
regulation of production of molecular mediator of immune response GO:0002700 1 0.012
positive regulation of glucose transport GO:0010828 1 0.012
regulation of rna biosynthetic process GO:2001141 213 0.012
stem cell differentiation GO:0048863 117 0.012
organelle assembly GO:0070925 110 0.012
mesenchymal cell development GO:0014031 78 0.012
regulation of multicellular organismal development GO:2000026 223 0.012
organic anion transport GO:0015711 15 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.011
somatic muscle development GO:0007525 4 0.011
inositol lipid mediated signaling GO:0048017 2 0.011
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.011
meiotic nuclear division GO:0007126 4 0.011
internal protein amino acid acetylation GO:0006475 2 0.011
cellular aromatic compound metabolic process GO:0006725 295 0.011
peptidyl serine modification GO:0018209 2 0.011
protein heterooligomerization GO:0051291 1 0.011
regulation of mrna processing GO:0050684 3 0.011
regulation of multicellular organismal metabolic process GO:0044246 2 0.011
ion transmembrane transport GO:0034220 91 0.011
digestive tract development GO:0048565 265 0.011
regulation of cell death GO:0010941 103 0.011
positive regulation of multi organism process GO:0043902 3 0.011
cell growth GO:0016049 57 0.011
cellular hormone metabolic process GO:0034754 19 0.011
positive regulation of cell adhesion GO:0045785 1 0.011
sarcomere organization GO:0045214 26 0.011
lipid catabolic process GO:0016042 4 0.011
system process GO:0003008 185 0.011
cellular catabolic process GO:0044248 27 0.011
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.011
synaptic growth at neuromuscular junction GO:0051124 2 0.011
protein targeting to nucleus GO:0044744 3 0.011
organelle localization GO:0051640 49 0.011
oocyte maturation GO:0001556 4 0.011
regulation of nucleic acid templated transcription GO:1903506 213 0.011
negative regulation of response to stimulus GO:0048585 104 0.010
growth GO:0040007 174 0.010
cellular response to hormone stimulus GO:0032870 39 0.010
protein import into nucleus GO:0006606 3 0.010
gland development GO:0048732 143 0.010
neuron projection guidance GO:0097485 86 0.010
actin filament polymerization GO:0030041 2 0.010
cell adhesion mediated by integrin GO:0033627 1 0.010
organic substance transport GO:0071702 58 0.010
cation transport GO:0006812 81 0.010
transmembrane transport GO:0055085 120 0.010
regulation of protein import into nucleus GO:0042306 2 0.010
regulation of cellular biosynthetic process GO:0031326 245 0.010
regulation of cell communication GO:0010646 232 0.010
heart development GO:0007507 313 0.010
positive regulation of protein polymerization GO:0032273 2 0.010
regulation of collagen metabolic process GO:0010712 2 0.010
protein targeting to membrane GO:0006612 1 0.010
regulation of protein localization to plasma membrane GO:1903076 1 0.010
positive regulation of macromolecule metabolic process GO:0010604 93 0.010

ggcx disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.037
inherited metabolic disorder DOID:655 0 0.037
disease of anatomical entity DOID:7 0 0.016
cardiovascular system disease DOID:1287 0 0.016
nervous system disease DOID:863 0 0.014
myopathy DOID:423 0 0.011
muscular disease DOID:0080000 0 0.011
heart disease DOID:114 0 0.011
cardiomyopathy DOID:0050700 0 0.011
intrinsic cardiomyopathy DOID:0060036 0 0.011
musculoskeletal system disease DOID:17 0 0.011
muscle tissue disease DOID:66 0 0.011