Danio rerio

13 known processes

col2a1a

collagen type II, alpha-1a

(Aliases: wu:fb38c06,coll2a1,fc10c01,wu:fc10c01,fb38c06,col2a1)

col2a1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryonic organ morphogenesis GO:0048562 274 0.995
Human Mouse
embryonic skeletal system development GO:0048706 97 0.985
Human
sensory organ development GO:0007423 393 0.985
Mouse
cellular biosynthetic process GO:0044249 286 0.980
embryonic viscerocranium morphogenesis GO:0048703 52 0.978
cartilage condensation GO:0001502 3 0.976
Mouse
regulation of rna biosynthetic process GO:2001141 213 0.975
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.950
neuron projection guidance GO:0097485 86 0.926
morphogenesis of embryonic epithelium GO:0016331 30 0.915
regulation of nucleic acid templated transcription GO:1903506 213 0.908
mesoderm development GO:0007498 88 0.883
nucleic acid templated transcription GO:0097659 181 0.879
regulation of transcription involved in cell fate commitment GO:0060850 1 0.878
positive regulation of biosynthetic process GO:0009891 68 0.875
embryonic skeletal system morphogenesis GO:0048704 93 0.848
Human
regeneration GO:0031099 91 0.848
Zebrafish
macromolecule biosynthetic process GO:0009059 227 0.846
organic substance biosynthetic process GO:1901576 289 0.840
cell fate commitment GO:0045165 99 0.835
embryonic cranial skeleton morphogenesis GO:0048701 90 0.825
positive regulation of metabolic process GO:0009893 108 0.824
forebrain development GO:0030900 96 0.815
skeletal system development GO:0001501 181 0.811
Human Zebrafish Mouse Rat
chondrocyte development GO:0002063 4 0.811
regulation of apoptotic process GO:0042981 98 0.806
Mouse
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.806
cellular macromolecule metabolic process GO:0044260 391 0.800
Mouse
embryonic skeletal joint development GO:0072498 3 0.798
Human
cellular aromatic compound metabolic process GO:0006725 295 0.775
regulation of cell development GO:0060284 100 0.752
dorsal ventral pattern formation GO:0009953 125 0.749
cellular component morphogenesis GO:0032989 336 0.743
morphogenesis of an epithelium GO:0002009 333 0.735
regionalization GO:0003002 274 0.731
axonogenesis GO:0007409 152 0.730
transcription dna templated GO:0006351 181 0.716
skeletal system morphogenesis GO:0048705 102 0.706
Human Mouse Rat
embryonic skeletal joint morphogenesis GO:0060272 3 0.703
Human
regulation of nitrogen compound metabolic process GO:0051171 251 0.701
regulation of primary metabolic process GO:0080090 311 0.698
epithelial tube formation GO:0072175 19 0.697
brain development GO:0007420 293 0.689
embryonic limb morphogenesis GO:0030326 2 0.688
neuron projection development GO:0031175 180 0.684
developmental pigmentation GO:0048066 48 0.678
nucleobase containing compound biosynthetic process GO:0034654 205 0.671
stem cell proliferation GO:0072089 4 0.671
periodic partitioning GO:0007365 1 0.670
positive regulation of nucleic acid templated transcription GO:1903508 57 0.657
appendage morphogenesis GO:0035107 56 0.647
Zebrafish Mouse
oligodendrocyte differentiation GO:0048709 23 0.639
sprouting angiogenesis GO:0002040 53 0.629
notochord development GO:0030903 54 0.623
aromatic compound biosynthetic process GO:0019438 217 0.618
regulation of chondrocyte differentiation GO:0032330 1 0.617
ectodermal placode development GO:0071696 37 0.617
regulation of endothelial cell proliferation GO:0001936 1 0.616
regulation of biosynthetic process GO:0009889 250 0.608
collagen metabolic process GO:0032963 2 0.602
regulation of transcription dna templated GO:0006355 213 0.602
somite development GO:0061053 96 0.577
apoptotic process GO:0006915 116 0.569
Mouse
fin regeneration GO:0031101 51 0.568
Zebrafish
cell morphogenesis involved in differentiation GO:0000904 195 0.567
endodermal cell fate commitment GO:0001711 18 0.565
regulation of anatomical structure morphogenesis GO:0022603 130 0.547
regulation of cellular biosynthetic process GO:0031326 245 0.536
positive regulation of gene expression GO:0010628 71 0.530
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.527
embryonic neurocranium morphogenesis GO:0048702 15 0.514
muscle organ development GO:0007517 101 0.512
mesenchymal cell proliferation GO:0010463 1 0.511
epithelial tube morphogenesis GO:0060562 148 0.511
positive regulation of macromolecule metabolic process GO:0010604 93 0.510
pectoral fin development GO:0033339 50 0.499
Zebrafish
regulation of rna metabolic process GO:0051252 224 0.489
positive regulation of transcription dna templated GO:0045893 57 0.488
tissue regeneration GO:0042246 74 0.484
Zebrafish
cell aggregation GO:0098743 3 0.470
Mouse
blood vessel morphogenesis GO:0048514 216 0.467
regulation of macromolecule metabolic process GO:0060255 317 0.462
Mouse
blood vessel development GO:0001568 246 0.460
bone morphogenesis GO:0060349 11 0.458
Mouse Rat
regulation of epithelial cell proliferation GO:0050678 3 0.455
pigmentation GO:0043473 85 0.453
biosynthetic process GO:0009058 294 0.439
hindbrain development GO:0030902 91 0.435
transcription from rna polymerase ii promoter GO:0006366 80 0.435
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.430
anterior commissure morphogenesis GO:0021960 3 0.424
cellular macromolecule biosynthetic process GO:0034645 224 0.422
positive regulation of cell differentiation GO:0045597 30 0.414
inner ear development GO:0048839 126 0.407
Mouse
positive regulation of cellular biosynthetic process GO:0031328 68 0.400
positive regulation of rna metabolic process GO:0051254 59 0.395
chordate embryonic development GO:0043009 271 0.374
Human
negative regulation of biological process GO:0048519 304 0.373
Mouse
positive regulation of cellular process GO:0048522 201 0.370
cell fate specification GO:0001708 68 0.370
foregut morphogenesis GO:0007440 4 0.366
limb bud formation GO:0060174 2 0.358
Mouse
muscle tissue development GO:0060537 110 0.356
endoderm development GO:0007492 49 0.345
smoothened signaling pathway GO:0007224 30 0.344
positive regulation of cellular metabolic process GO:0031325 94 0.340
positive regulation of stem cell proliferation GO:2000648 1 0.338
digestive tract development GO:0048565 265 0.337
cellular response to growth factor stimulus GO:0071363 39 0.336
Mouse
ear development GO:0043583 127 0.331
Mouse
neural tube development GO:0021915 62 0.330
mesenchyme development GO:0060485 127 0.329
embryonic pattern specification GO:0009880 44 0.324
positive regulation of rna biosynthetic process GO:1902680 57 0.323
angiogenesis GO:0001525 158 0.318
myelination GO:0042552 18 0.318
regulation of cellular metabolic process GO:0031323 320 0.318
regulation of metabolic process GO:0019222 359 0.318
Mouse
negative regulation of muscle cell differentiation GO:0051148 1 0.315
neuron projection morphogenesis GO:0048812 161 0.307
embryonic appendage morphogenesis GO:0035113 30 0.307
cell surface receptor signaling pathway GO:0007166 325 0.306
Mouse
myotube differentiation GO:0014902 45 0.300
ectodermal placode morphogenesis GO:0071697 32 0.297
inositol lipid mediated signaling GO:0048017 2 0.288
lateral line nerve glial cell development GO:0048937 6 0.283
renal system vasculature development GO:0061437 2 0.282
cardiogenic plate morphogenesis GO:0003142 1 0.282
regulation of nervous system development GO:0051960 90 0.279
pharyngeal system development GO:0060037 18 0.277
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.276
cognition GO:0050890 1 0.270
epidermis development GO:0008544 48 0.268
generation of neurons GO:0048699 385 0.267
negative regulation of signaling GO:0023057 96 0.266
Mouse
dendrite guidance GO:0070983 0 0.265
bone mineralization GO:0030282 9 0.264
cellular nitrogen compound biosynthetic process GO:0044271 218 0.260
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.258
tube formation GO:0035148 25 0.257
regulation of biological quality GO:0065008 263 0.256
Mouse
multicellular organismal metabolic process GO:0044236 2 0.255
bmp signaling pathway GO:0030509 52 0.253
central nervous system development GO:0007417 387 0.252
Mouse
amide transport GO:0042886 12 0.250
immune system process GO:0002376 241 0.244
cell projection organization GO:0030030 284 0.242
developmental growth involved in morphogenesis GO:0060560 86 0.234
Rat
neuron fate commitment GO:0048663 26 0.232
fin development GO:0033333 77 0.231
Zebrafish
chemotaxis GO:0006935 104 0.230
locomotion GO:0040011 313 0.223
death GO:0016265 121 0.221
Mouse
rna biosynthetic process GO:0032774 181 0.220
central nervous system neuron differentiation GO:0021953 74 0.219
epidermal cell fate specification GO:0009957 4 0.218
glomerulus vasculature development GO:0072012 2 0.215
epithelial cell morphogenesis GO:0003382 2 0.214
cartilage development involved in endochondral bone morphogenesis GO:0060351 8 0.211
Mouse Rat
response to wounding GO:0009611 116 0.205
Zebrafish
collagen biosynthetic process GO:0032964 2 0.202
polarized epithelial cell differentiation GO:0030859 4 0.200
dorsal ventral neural tube patterning GO:0021904 1 0.197
cell fate specification involved in pattern specification GO:0060573 3 0.196
hormone transport GO:0009914 2 0.194
multicellular organismal macromolecule metabolic process GO:0044259 2 0.194
connective tissue development GO:0061448 99 0.193
Zebrafish Mouse Rat
regulation of multicellular organismal development GO:2000026 223 0.191
appendage development GO:0048736 80 0.190
Zebrafish Mouse
gene expression GO:0010467 252 0.190
Mouse
positive regulation of epithelial cell proliferation GO:0050679 1 0.188
cell motility GO:0048870 244 0.185
axon extension GO:0048675 45 0.185
embryonic organ development GO:0048568 381 0.182
glial cell differentiation GO:0010001 42 0.178
regulation of gene expression GO:0010468 265 0.176
Mouse
regulation of bone mineralization GO:0030500 2 0.175
ossification GO:0001503 23 0.175
Zebrafish Mouse
negative regulation of signal transduction GO:0009968 94 0.174
Mouse
cranial suture morphogenesis GO:0060363 1 0.173
regulation of wnt signaling pathway GO:0030111 53 0.173
mesoderm morphogenesis GO:0048332 51 0.173
morphogenesis of an epithelial fold GO:0060571 1 0.167
organic cyclic compound metabolic process GO:1901360 301 0.166
rna metabolic process GO:0016070 219 0.165
regulation of mesenchymal cell proliferation GO:0010464 1 0.165
neural plate development GO:0001840 10 0.161
positive regulation of neurogenesis GO:0050769 24 0.160
regulation of developmental process GO:0050793 247 0.160
protein modification process GO:0036211 100 0.158
smooth muscle tissue development GO:0048745 1 0.157
inner ear receptor cell differentiation GO:0060113 29 0.154
segment polarity determination GO:0007367 1 0.154
sensory organ morphogenesis GO:0090596 200 0.152
Mouse
cell morphogenesis GO:0000902 289 0.150
digestive system development GO:0055123 289 0.145
heterocycle biosynthetic process GO:0018130 215 0.144
sympathetic nervous system development GO:0048485 3 0.144
lateral line system development GO:0048925 76 0.143
organic cyclic compound biosynthetic process GO:1901362 223 0.143
neural plate pattern specification GO:0060896 12 0.141
system process GO:0003008 185 0.141
Human
negative regulation of cellular process GO:0048523 283 0.140
Mouse
neural crest cell differentiation GO:0014033 72 0.140
nitrogen compound metabolic process GO:0006807 319 0.139
neuron projection extension GO:1990138 45 0.138
cell cycle GO:0007049 93 0.135
neuronal action potential GO:0019228 18 0.133
ear morphogenesis GO:0042471 64 0.133
Mouse
hormone secretion GO:0046879 2 0.131
skeletal muscle tissue development GO:0007519 67 0.128
cellular nitrogen compound metabolic process GO:0034641 290 0.128
vascular endothelial growth factor receptor signaling pathway GO:0048010 13 0.125
negative regulation of cell communication GO:0010648 96 0.124
Mouse
regulation of cartilage development GO:0061035 7 0.124
negative regulation of epithelial cell proliferation GO:0050680 1 0.123
establishment of epithelial cell polarity GO:0090162 2 0.120
protein complex subunit organization GO:0071822 46 0.119
Human Mouse
motor neuron axon guidance GO:0008045 23 0.118
regulation of protein catabolic process GO:0042176 1 0.117
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.117
cellular component biogenesis GO:0044085 178 0.116
vasculature development GO:0001944 278 0.114
hepaticobiliary system development GO:0061008 98 0.113
neurological system process GO:0050877 62 0.112
Human
neuron development GO:0048666 262 0.111
response to chemical GO:0042221 320 0.109
Mouse Rat
embryo development ending in birth or egg hatching GO:0009792 271 0.108
Human
aminoglycan metabolic process GO:0006022 9 0.107
determination of bilateral symmetry GO:0009855 204 0.106
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.103
growth GO:0040007 174 0.102
Zebrafish Rat
regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 8 0.101
cell cell signaling GO:0007267 52 0.100
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.100
regulation of blood vessel size GO:0050880 2 0.099
modification dependent macromolecule catabolic process GO:0043632 3 0.098
kidney development GO:0001822 92 0.098
embryonic heart tube formation GO:0003144 1 0.098
camera type eye morphogenesis GO:0048593 108 0.098
glial cell fate specification GO:0021780 4 0.097
neural tube formation GO:0001841 16 0.097
epithelial cell differentiation GO:0030855 116 0.096
nucleobase containing compound metabolic process GO:0006139 274 0.096
determination of intestine left right asymmetry GO:0071908 2 0.096
aging GO:0007568 2 0.096
organ formation GO:0048645 17 0.095
endodermal cell fate determination GO:0007493 2 0.094
formation of primary germ layer GO:0001704 62 0.093
spinal cord development GO:0021510 46 0.092
nephron epithelium morphogenesis GO:0072088 1 0.092
regulation of glial cell differentiation GO:0045685 4 0.091
nucleic acid metabolic process GO:0090304 244 0.091
embryonic epithelial tube formation GO:0001838 17 0.091
pigment cell differentiation GO:0050931 38 0.089
cellular response to external stimulus GO:0071496 2 0.088
Rat
otic placode formation GO:0043049 23 0.088
specification of symmetry GO:0009799 204 0.086
neuromast hair cell development GO:0035675 6 0.085
inner ear receptor cell fate commitment GO:0060120 4 0.085
endocardium formation GO:0060214 1 0.085
kidney vasculature development GO:0061440 2 0.084
eye development GO:0001654 277 0.084
liver development GO:0001889 96 0.084
regulation of membrane potential GO:0042391 23 0.084
retinal ganglion cell axon guidance GO:0031290 35 0.084
wnt signaling pathway GO:0016055 80 0.083
astrocyte differentiation GO:0048708 1 0.083
mesenchymal cell development GO:0014031 78 0.082
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.081
posterior lateral line nerve glial cell morphogenesis involved in differentiation GO:0048942 5 0.081
cellular response to endogenous stimulus GO:0071495 68 0.079
Mouse Rat
developmental induction GO:0031128 10 0.079
germ cell migration GO:0008354 8 0.079
regulation of collagen metabolic process GO:0010712 2 0.079
mesenchymal cell differentiation GO:0048762 87 0.078
positive regulation of developmental process GO:0051094 50 0.076
cell cell signaling involved in cell fate commitment GO:0045168 12 0.076
negative regulation of angiogenesis GO:0016525 7 0.076
developmental cell growth GO:0048588 52 0.076
olfactory bulb axon guidance GO:0071678 3 0.076
extracellular matrix assembly GO:0085029 1 0.075
positive regulation of biological process GO:0048518 253 0.075
regulation of signal transduction GO:0009966 225 0.075
Mouse
glial cell development GO:0021782 20 0.075
regulation of cell cycle GO:0051726 52 0.075
wound healing GO:0042060 90 0.075
Zebrafish
sensory system development GO:0048880 76 0.073
camera type eye development GO:0043010 222 0.072
regulation of neuron migration GO:2001222 2 0.072
notochord morphogenesis GO:0048570 17 0.072
head development GO:0060322 303 0.072
positive regulation of multicellular organismal process GO:0051240 52 0.071
cartilage morphogenesis GO:0060536 13 0.069
Zebrafish
posterior lateral line system development GO:0048915 46 0.069
defense response to bacterium GO:0042742 22 0.069
response to external stimulus GO:0009605 264 0.068
Zebrafish Rat
response to other organism GO:0051707 97 0.067
epithelial cell proliferation GO:0050673 17 0.067
dorsal ventral axis specification GO:0009950 14 0.066
regulation of macromolecule biosynthetic process GO:0010556 225 0.066
cellular protein catabolic process GO:0044257 4 0.065
anterior lateral line nerve development GO:0048909 4 0.064
retina morphogenesis in camera type eye GO:0060042 79 0.064
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.064
nerve development GO:0021675 45 0.063
posterior lateral line nerve development GO:0048918 8 0.063
negative regulation of nervous system development GO:0051961 22 0.063
bmp signaling pathway involved in heart jogging GO:0003303 14 0.062
gland development GO:0048732 143 0.062
positive regulation of response to stimulus GO:0048584 80 0.061
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.059
negative regulation of response to stimulus GO:0048585 104 0.059
Mouse
endocardium development GO:0003157 9 0.059
hindbrain morphogenesis GO:0021575 22 0.059
auditory receptor cell fate commitment GO:0009912 4 0.059
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.059
positive regulation of gastrulation GO:2000543 2 0.059
ectodermal placode formation GO:0060788 26 0.059
neural tube patterning GO:0021532 33 0.059
optic placode formation involved in camera type eye formation GO:0046619 3 0.059
phosphatidylinositol mediated signaling GO:0048015 2 0.058
fin morphogenesis GO:0033334 53 0.057
Zebrafish
axis elongation GO:0003401 31 0.057
swim bladder development GO:0048794 19 0.057
septum transversum development GO:0003343 4 0.055
inner ear morphogenesis GO:0042472 63 0.055
Mouse
diencephalon development GO:0021536 58 0.055
endocardium morphogenesis GO:0003160 4 0.055
regulation of skeletal muscle fiber development GO:0048742 2 0.054
biological adhesion GO:0022610 40 0.054
positive regulation of muscle tissue development GO:1901863 1 0.054
apoptotic process involved in morphogenesis GO:0060561 2 0.054
regulation of smoothened signaling pathway GO:0008589 18 0.052
establishment or maintenance of cell polarity GO:0007163 29 0.052
positive regulation of gliogenesis GO:0014015 2 0.052
otic vesicle development GO:0071599 42 0.052
Mouse
striated muscle cell development GO:0055002 108 0.051
cell differentiation in spinal cord GO:0021515 40 0.051
regulation of multicellular organismal process GO:0051239 277 0.050
Zebrafish
cell part morphogenesis GO:0032990 246 0.050
cellular component assembly GO:0022607 170 0.050
cell growth GO:0016049 57 0.050
positive regulation of cell development GO:0010720 25 0.050
axon development GO:0061564 166 0.050
cellular response to chemical stimulus GO:0070887 157 0.049
Mouse Rat
sex determination GO:0007530 1 0.049
taxis GO:0042330 109 0.048
regulation of cell death GO:0010941 103 0.048
Mouse
limb development GO:0060173 8 0.047
Mouse
heart morphogenesis GO:0003007 156 0.047
Mouse
regulation of multicellular organism growth GO:0040014 4 0.047
vasculogenesis GO:0001570 41 0.046
canonical wnt signaling pathway GO:0060070 48 0.045
cell projection morphogenesis GO:0048858 244 0.045
negative regulation of reproductive process GO:2000242 3 0.045
positive regulation of glial cell differentiation GO:0045687 1 0.045
neural plate morphogenesis GO:0001839 7 0.044
mesodermal cell differentiation GO:0048333 21 0.044
establishment of cell polarity GO:0030010 18 0.044
regulation of cell fate commitment GO:0010453 22 0.043
negative regulation of defense response GO:0031348 2 0.043
negative regulation of immune system process GO:0002683 7 0.043
gastrulation with mouth forming second GO:0001702 44 0.043
phosphorylation GO:0016310 69 0.043
establishment of protein localization to organelle GO:0072594 4 0.043
tissue remodeling GO:0048771 4 0.042
ameboidal type cell migration GO:0001667 143 0.042
neuron migration GO:0001764 22 0.042
defense response to other organism GO:0098542 33 0.042
regulation of reproductive process GO:2000241 4 0.041
ensheathment of neurons GO:0007272 18 0.041
negative regulation of cell fate commitment GO:0010454 13 0.040
negative regulation of smoothened signaling pathway GO:0045879 6 0.040
angioblast cell differentiation GO:0035779 2 0.040
regulation of protein ubiquitination GO:0031396 3 0.040
positive regulation of muscle organ development GO:0048636 1 0.039
mechanoreceptor differentiation GO:0042490 37 0.039
melanocyte differentiation GO:0030318 26 0.039
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 22 0.039
enzyme linked receptor protein signaling pathway GO:0007167 106 0.039
lens development in camera type eye GO:0002088 22 0.039
regulation of angiogenesis GO:0045765 26 0.038
specification of organ identity GO:0010092 2 0.038
axon guidance GO:0007411 86 0.038
regulation of cell projection organization GO:0031344 44 0.038
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.038
endocrine pancreas development GO:0031018 27 0.038
cardioblast differentiation GO:0010002 9 0.038
apoptotic process involved in development GO:1902742 2 0.038
i kappab kinase nf kappab signaling GO:0007249 4 0.037
inner ear receptor cell development GO:0060119 20 0.037
neuromast development GO:0048884 46 0.036
extrinsic apoptotic signaling pathway GO:0097191 3 0.036
Mouse
multicellular organismal signaling GO:0035637 22 0.036
regulation of dendrite development GO:0050773 3 0.036
eye morphogenesis GO:0048592 144 0.036
regulation of tube size GO:0035150 2 0.036
odontogenesis of dentin containing tooth GO:0042475 1 0.036
negative regulation of wnt signaling pathway GO:0030178 30 0.036
regulation of neuron projection development GO:0010975 40 0.035
negative regulation of transcription elongation from rna polymerase ii promoter GO:0034244 1 0.035
response to stress GO:0006950 263 0.034
Zebrafish
otic vesicle formation GO:0030916 27 0.034
endothelial cell morphogenesis GO:0001886 1 0.034
peptide transport GO:0015833 1 0.034
peripheral nervous system neuron differentiation GO:0048934 28 0.033
regulation of cell activation GO:0050865 1 0.033
behavior GO:0007610 74 0.032
limbic system development GO:0021761 16 0.032
regulation of cellular protein metabolic process GO:0032268 52 0.032
glial cell migration GO:0008347 3 0.032
cellular macromolecule localization GO:0070727 21 0.032
cardiocyte differentiation GO:0035051 44 0.032
positive regulation of epithelial cell differentiation GO:0030858 2 0.032
negative regulation of multicellular organismal process GO:0051241 69 0.032
regulation of mitochondrion organization GO:0010821 1 0.032
single organism localization GO:1902578 225 0.032
negative regulation of canonical wnt signaling pathway GO:0090090 21 0.031
neural plate anterior posterior regionalization GO:0021999 8 0.031
retina development in camera type eye GO:0060041 146 0.031
renal system vasculature morphogenesis GO:0061438 1 0.031
central nervous system myelination GO:0022010 2 0.030
regulation of establishment of planar polarity GO:0090175 4 0.030
positive regulation of apoptotic process GO:0043065 29 0.030
heterocycle metabolic process GO:0046483 290 0.029
cardiac conduction GO:0061337 3 0.029
muscle structure development GO:0061061 196 0.029
positive regulation of endothelial cell differentiation GO:0045603 2 0.029
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.029
neuron fate specification GO:0048665 20 0.029
hemopoiesis GO:0030097 183 0.029
regulation of epithelial to mesenchymal transition GO:0010717 3 0.029
stem cell differentiation GO:0048863 117 0.029
epithelial cell development GO:0002064 42 0.029
regulation of developmental growth GO:0048638 38 0.029
regulation of cell migration involved in sprouting angiogenesis GO:0090049 3 0.028
neural crest cell migration GO:0001755 42 0.028
heart formation GO:0060914 13 0.028
renal system development GO:0072001 94 0.027
negative regulation of map kinase activity GO:0043407 2 0.027
cardiac muscle fiber development GO:0048739 3 0.027
myotome development GO:0061055 1 0.027
tube morphogenesis GO:0035239 349 0.027
lateral line nerve development GO:0048892 9 0.027
fatty acid transport GO:0015908 1 0.027
axon ensheathment in central nervous system GO:0032291 2 0.027
exocrine system development GO:0035272 28 0.027
glycoprotein metabolic process GO:0009100 23 0.027
Mouse
negative regulation of macromolecule metabolic process GO:0010605 76 0.027
cell migration GO:0016477 237 0.026
locomotory behavior GO:0007626 34 0.026
regulation of mitotic cell cycle GO:0007346 25 0.026
cellular protein modification process GO:0006464 100 0.026
regulation of sarcomere organization GO:0060297 2 0.026
monocyte differentiation GO:0030224 2 0.026
heart valve morphogenesis GO:0003179 8 0.026
morphogenesis of a branching structure GO:0001763 21 0.025
glial cell fate commitment GO:0021781 6 0.025
negative regulation of cell differentiation GO:0045596 46 0.025
protein secretion GO:0009306 1 0.025
cellular response to fibroblast growth factor stimulus GO:0044344 22 0.025
positive regulation of lipid metabolic process GO:0045834 1 0.025
ubiquitin dependent protein catabolic process GO:0006511 3 0.025
basement membrane assembly GO:0070831 3 0.024
phagocytosis GO:0006909 3 0.024
defense response GO:0006952 47 0.024
peripheral nervous system development GO:0007422 55 0.024
camera type eye photoreceptor cell differentiation GO:0060219 19 0.024
morphogenesis of an epithelial sheet GO:0002011 49 0.024
regulation of neurogenesis GO:0050767 87 0.024
response to corticosteroid GO:0031960 1 0.024
endocrine system development GO:0035270 65 0.024
establishment of epithelial cell apical basal polarity GO:0045198 2 0.023
urogenital system development GO:0001655 97 0.023
mucopolysaccharide metabolic process GO:1903510 2 0.023
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.023
catechol containing compound metabolic process GO:0009712 2 0.023
regulation of hormone levels GO:0010817 21 0.023
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.023
bone development GO:0060348 14 0.023
Mouse Rat
regulation of bmp signaling pathway GO:0030510 39 0.023
bone remodeling GO:0046849 2 0.023
epidermal cell differentiation GO:0009913 36 0.022
regulation of embryonic development GO:0045995 47 0.022
common bile duct development GO:0061009 13 0.022
endodermal cell fate specification GO:0001714 17 0.022
mitotic cell cycle process GO:1903047 48 0.022

col2a1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
bone disease DOID:0080001 0 0.829
Human
disease of anatomical entity DOID:7 0 0.829
Human
musculoskeletal system disease DOID:17 0 0.829
Human
connective tissue disease DOID:65 0 0.829
Human
osteochondrodysplasia DOID:2256 0 0.207
Human
bone development disease DOID:0080006 0 0.207
Human
dysostosis DOID:1934 0 0.043
nervous system disease DOID:863 0 0.034