Danio rerio

140 known processes

prox1

prospero-related homeobox gene 1

(Aliases: zgc:111888)

prox1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nitrogen compound metabolic process GO:0006807 319 0.994
regulation of rna metabolic process GO:0051252 224 0.987
regulation of rna biosynthetic process GO:2001141 213 0.962
negative regulation of biological process GO:0048519 304 0.952
cellular response to hormone stimulus GO:0032870 39 0.951
head development GO:0060322 303 0.941
regulation of nitrogen compound metabolic process GO:0051171 251 0.923
cellular nitrogen compound metabolic process GO:0034641 290 0.918
cellular aromatic compound metabolic process GO:0006725 295 0.916
posterior lateral line system development GO:0048915 46 0.915
neuron projection morphogenesis GO:0048812 161 0.866
Fly
skin development GO:0043588 54 0.864
regulation of cellular biosynthetic process GO:0031326 245 0.833
regulation of nucleic acid templated transcription GO:1903506 213 0.818
locomotion GO:0040011 313 0.811
regulation of neuron migration GO:2001222 2 0.808
axonogenesis GO:0007409 152 0.804
Fly
response to drug GO:0042493 3 0.798
transcription dna templated GO:0006351 181 0.798
nucleic acid metabolic process GO:0090304 244 0.795
endocrine system development GO:0035270 65 0.790
posterior lateral line development GO:0048916 38 0.781
rna biosynthetic process GO:0032774 181 0.766
biosynthetic process GO:0009058 294 0.766
forebrain development GO:0030900 96 0.763
response to hormone GO:0009725 48 0.760
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.759
regulation of cellular metabolic process GO:0031323 320 0.751
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.751
Mouse Fly
regulation of primary metabolic process GO:0080090 311 0.745
heterocycle biosynthetic process GO:0018130 215 0.727
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.724
regulation of macromolecule metabolic process GO:0060255 317 0.718
positive regulation of neuron migration GO:2001224 2 0.702
aromatic compound biosynthetic process GO:0019438 217 0.692
epidermal cell differentiation GO:0009913 36 0.692
organic cyclic compound biosynthetic process GO:1901362 223 0.690
blood vessel morphogenesis GO:0048514 216 0.677
Mouse
nucleobase containing compound metabolic process GO:0006139 274 0.675
regulation of biosynthetic process GO:0009889 250 0.675
pancreatic a cell development GO:0003322 2 0.664
cell motility GO:0048870 244 0.662
cellular component movement GO:0006928 335 0.654
brain development GO:0007420 293 0.633
mechanosensory lateral line system development GO:0048881 49 0.633
heart contraction GO:0060047 71 0.615
negative regulation of biosynthetic process GO:0009890 55 0.612
Mouse Fly
rna metabolic process GO:0016070 219 0.607
hair cell differentiation GO:0035315 32 0.606
innervation GO:0060384 3 0.606
Fly
aging GO:0007568 2 0.582
neuron projection development GO:0031175 180 0.576
Fly
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.536
Fly
generation of neurons GO:0048699 385 0.528
gene expression GO:0010467 252 0.519
behavior GO:0007610 74 0.518
Fly
cell migration involved in heart formation GO:0060974 10 0.505
cellular macromolecule biosynthetic process GO:0034645 224 0.501
larval development GO:0002164 2 0.499
Worm
heart process GO:0003015 71 0.498
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.492
Mouse Fly
eye morphogenesis GO:0048592 144 0.491
Mouse Fly
neuromast hair cell differentiation GO:0048886 12 0.485
ear development GO:0043583 127 0.483
Mouse
photoreceptor cell fate specification GO:0043704 1 0.481
Fly
heterocycle metabolic process GO:0046483 290 0.479
signal transduction GO:0007165 455 0.479
positive regulation of epithelial cell differentiation GO:0030858 2 0.476
cell morphogenesis GO:0000902 289 0.464
Mouse Fly
inner ear development GO:0048839 126 0.459
Mouse
positive regulation of tyrosine phosphorylation of stat protein GO:0042531 1 0.452
central nervous system development GO:0007417 387 0.449
organic cyclic compound metabolic process GO:1901360 301 0.445
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.440
Mouse
macromolecule biosynthetic process GO:0009059 227 0.440
transcription from rna polymerase ii promoter GO:0006366 80 0.433
Mouse Fly
cell morphogenesis involved in differentiation GO:0000904 195 0.431
Mouse Fly
regulation of tyrosine phosphorylation of stat protein GO:0042509 1 0.427
venous endothelial cell migration involved in lymph vessel development GO:0060855 4 0.422
regulation of jak stat cascade GO:0046425 3 0.420
central nervous system neuron differentiation GO:0021953 74 0.419
nitric oxide mediated signal transduction GO:0007263 2 0.419
cell projection organization GO:0030030 284 0.415
Fly
mechanoreceptor differentiation GO:0042490 37 0.411
negative regulation of endothelial cell migration GO:0010596 1 0.411
regulation of organ growth GO:0046620 3 0.403
Mouse
nucleic acid templated transcription GO:0097659 181 0.396
lymphangiogenesis GO:0001946 25 0.388
lateral line system development GO:0048925 76 0.386
lymph vessel morphogenesis GO:0036303 25 0.384
pancreas development GO:0031016 84 0.378
Mouse
nucleobase containing compound biosynthetic process GO:0034654 205 0.366
organic substance biosynthetic process GO:1901576 289 0.366
negative regulation of gene expression GO:0010629 65 0.358
Mouse Fly
response to carbohydrate GO:0009743 3 0.357
actin filament based process GO:0030029 64 0.356
skeletal system development GO:0001501 181 0.354
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.341
Mouse
regulation of epithelial cell proliferation GO:0050678 3 0.337
hormone mediated signaling pathway GO:0009755 9 0.330
phenol containing compound biosynthetic process GO:0046189 4 0.328
digestive system development GO:0055123 289 0.326
positive regulation of biosynthetic process GO:0009891 68 0.324
Mouse
negative regulation of neural precursor cell proliferation GO:2000178 1 0.322
Fly
posterior lateral line neuromast development GO:0048919 20 0.321
neuroblast differentiation GO:0014016 1 0.316
Fly
embryo development ending in birth or egg hatching GO:0009792 271 0.312
sensory system development GO:0048880 76 0.310
positive regulation of jak stat cascade GO:0046427 2 0.308
cellular ketone metabolic process GO:0042180 11 0.307
regulation of metabolic process GO:0019222 359 0.301
cellular nitrogen compound biosynthetic process GO:0044271 218 0.297
phosphorus metabolic process GO:0006793 109 0.297
sensory organ development GO:0007423 393 0.292
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.292
Mouse Fly
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.284
adult behavior GO:0030534 2 0.282
cellular amine metabolic process GO:0044106 2 0.279
epidermis development GO:0008544 48 0.276
otolith development GO:0048840 32 0.275
dopaminergic neuron differentiation GO:0071542 14 0.274
auditory receptor cell fate commitment GO:0009912 4 0.271
endocrine pancreas development GO:0031018 27 0.270
hormone transport GO:0009914 2 0.268
regulation of cellular amino acid metabolic process GO:0006521 0 0.267
tube morphogenesis GO:0035239 349 0.263
cellular macromolecule metabolic process GO:0044260 391 0.260
epithelial cell differentiation GO:0030855 116 0.259
photoreceptor cell differentiation GO:0046530 55 0.257
Fly
transport GO:0006810 220 0.257
Fly
response to nitrogen compound GO:1901698 19 0.257
regionalization GO:0003002 274 0.256
positive regulation of metabolic process GO:0009893 108 0.256
Mouse Fly
response to inorganic substance GO:0010035 38 0.254
positive regulation of cellular amine metabolic process GO:0033240 0 0.253
determination of intestine left right asymmetry GO:0071908 2 0.251
digestive tract development GO:0048565 265 0.251
cell migration GO:0016477 237 0.250
regulation of tyrosine phosphorylation of stat3 protein GO:0042516 1 0.249
blood vessel development GO:0001568 246 0.249
Mouse
intracellular estrogen receptor signaling pathway GO:0030520 3 0.249
reproductive process GO:0022414 40 0.248
Fly
jak stat cascade GO:0007259 5 0.247
negative regulation of developmental process GO:0051093 65 0.245
Mouse Fly
diencephalon development GO:0021536 58 0.244
limbic system development GO:0021761 16 0.242
Mouse
camera type eye development GO:0043010 222 0.241
Mouse Fly
maintenance of location GO:0051235 4 0.231
regulation of hormone levels GO:0010817 21 0.230
blood vessel endothelial cell proliferation involved in sprouting angiogenesis GO:0002043 4 0.226
sensory organ morphogenesis GO:0090596 200 0.224
Mouse Fly
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.220
single organism metabolic process GO:0044710 217 0.217
response to hexose GO:0009746 3 0.217
tyrosine phosphorylation of stat protein GO:0007260 1 0.216
response to organic substance GO:0010033 153 0.215
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.215
Mouse Fly
positive regulation of biological process GO:0048518 253 0.209
Mouse Fly
regulation of cytokine production GO:0001817 3 0.209
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.202
Mouse
auditory receptor cell differentiation GO:0042491 15 0.201
regulation of oligodendrocyte differentiation GO:0048713 1 0.201
tissue migration GO:0090130 37 0.200
ventral spinal cord interneuron fate commitment GO:0060579 3 0.199
negative regulation of cellular metabolic process GO:0031324 77 0.198
Mouse Fly
rhythmic process GO:0048511 21 0.198
Mouse
aorta morphogenesis GO:0035909 3 0.197
Mouse
regulation of gene expression GO:0010468 265 0.196
neuromast development GO:0048884 46 0.195
positive regulation of tyrosine phosphorylation of stat3 protein GO:0042517 1 0.194
negative regulation of rna metabolic process GO:0051253 48 0.193
Mouse Fly
auditory receptor cell fate determination GO:0042668 2 0.193
multicellular organism reproduction GO:0032504 35 0.189
Fly
neuron fate determination GO:0048664 2 0.189
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.186
embryonic organ development GO:0048568 381 0.183
Mouse
negative regulation of multicellular organismal process GO:0051241 69 0.183
Fly
regulation of cellular ketone metabolic process GO:0010565 7 0.179
negative regulation of epithelial cell migration GO:0010633 1 0.179
cellular amino acid metabolic process GO:0006520 7 0.179
hematopoietic or lymphoid organ development GO:0048534 191 0.179
catechol containing compound biosynthetic process GO:0009713 2 0.176
neuroblast proliferation GO:0007405 2 0.174
Fly
neuromast deposition GO:0048885 9 0.173
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.172
Mouse
regulation of phosphorus metabolic process GO:0051174 43 0.172
regulation of transcription dna templated GO:0006355 213 0.170
cell part morphogenesis GO:0032990 246 0.170
Fly
positive regulation of cellular biosynthetic process GO:0031328 68 0.169
Mouse
exocrine system development GO:0035272 28 0.169
somitogenesis GO:0001756 87 0.169
response to glucose GO:0009749 3 0.167
positive regulation of nucleic acid templated transcription GO:1903508 57 0.165
Mouse
negative regulation of cellular biosynthetic process GO:0031327 55 0.165
Mouse Fly
glucose homeostasis GO:0042593 1 0.165
vasculature development GO:0001944 278 0.164
cellular component morphogenesis GO:0032989 336 0.164
regulation of stem cell proliferation GO:0072091 2 0.163
Fly
epithelial cell development GO:0002064 42 0.161
Mouse
cell proliferation GO:0008283 80 0.159
Mouse Fly
response to wounding GO:0009611 116 0.158
chemosensory behavior GO:0007635 1 0.155
inner ear receptor cell fate commitment GO:0060120 4 0.154
cellular biosynthetic process GO:0044249 286 0.154
regulation of glial cell differentiation GO:0045685 4 0.154
gland development GO:0048732 143 0.154
Mouse
thyroid gland development GO:0030878 12 0.149
olfactory bulb development GO:0021772 4 0.149
regulation of neural retina development GO:0061074 2 0.148
Fly
retina development in camera type eye GO:0060041 146 0.147
Mouse Fly
response to peptide hormone GO:0043434 6 0.147
cardiac cell fate commitment GO:0060911 1 0.146
entrainment of circadian clock GO:0009649 2 0.145
multi organism process GO:0051704 134 0.145
Fly
negative regulation of protein transport GO:0051224 3 0.145
taxis GO:0042330 109 0.143
Fly
response to chemical GO:0042221 320 0.142
Fly
developmental maturation GO:0021700 34 0.141
neuron projection guidance GO:0097485 86 0.138
Fly
cellular response to drug GO:0035690 1 0.137
negative regulation of locomotion GO:0040013 18 0.135
cell fate commitment GO:0045165 99 0.132
Mouse Fly
axon guidance GO:0007411 86 0.132
Fly
regulation of heart growth GO:0060420 2 0.132
Mouse
posterior lateral line neuromast hair cell differentiation GO:0048923 8 0.130
negative regulation of transcription dna templated GO:0045892 45 0.130
Mouse Fly
positive regulation of gliogenesis GO:0014015 2 0.130
regulation of cell migration GO:0030334 40 0.129
chordate embryonic development GO:0043009 271 0.128
response to abiotic stimulus GO:0009628 122 0.127
lateral line development GO:0048882 66 0.126
endocardium formation GO:0060214 1 0.125
Mouse
positive regulation of cell cycle GO:0045787 3 0.124
Mouse
negative regulation of rna biosynthetic process GO:1902679 45 0.120
Mouse Fly
ameboidal type cell migration GO:0001667 143 0.119
membrane repolarization GO:0086009 2 0.118
regulation of endothelial cell differentiation GO:0045601 3 0.117
digestive tract morphogenesis GO:0048546 231 0.117
neuron differentiation GO:0030182 353 0.116
epithelial cell fate commitment GO:0072148 11 0.116
homeostatic process GO:0042592 142 0.115
lipid metabolic process GO:0006629 52 0.115
regulation of retina development in camera type eye GO:1902866 2 0.113
Fly
single organism localization GO:1902578 225 0.112
Fly
organonitrogen compound metabolic process GO:1901564 74 0.112
regulation of developmental process GO:0050793 247 0.111
Mouse Fly
neuron migration GO:0001764 22 0.111
response to monosaccharide GO:0034284 3 0.111
phosphate containing compound metabolic process GO:0006796 108 0.111
ovulation cycle process GO:0022602 2 0.110
regulation of biological quality GO:0065008 263 0.110
oxoacid metabolic process GO:0043436 31 0.108
gabaergic neuron differentiation GO:0097154 2 0.107
negative regulation of epithelial cell proliferation GO:0050680 1 0.107
peripheral nervous system neuron differentiation GO:0048934 28 0.106
amine metabolic process GO:0009308 2 0.105
blood circulation GO:0008015 87 0.104
positive regulation of glial cell differentiation GO:0045687 1 0.104
enteroendocrine cell differentiation GO:0035883 9 0.104
regulation of response to nutrient levels GO:0032107 1 0.102
neuronal stem cell maintenance GO:0097150 2 0.101
Mouse
negative regulation of cellular process GO:0048523 283 0.100
response to oxygen containing compound GO:1901700 55 0.100
response to endogenous stimulus GO:0009719 83 0.100
single organism organelle organization GO:1902589 199 0.098
localization of cell GO:0051674 244 0.095
apoptotic process GO:0006915 116 0.093
embryonic organ morphogenesis GO:0048562 274 0.093
Mouse
response to steroid hormone GO:0048545 35 0.093
regulation of hormone secretion GO:0046883 2 0.093
regulation of intracellular signal transduction GO:1902531 57 0.093
heart development GO:0007507 313 0.092
Mouse
regulation of multicellular organismal process GO:0051239 277 0.092
Mouse Fly
cellular response to abiotic stimulus GO:0071214 4 0.091
carboxylic acid metabolic process GO:0019752 22 0.090
neuron development GO:0048666 262 0.089
regulation of cell motility GO:2000145 46 0.089
developmental programmed cell death GO:0010623 4 0.089
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.088
protein modification process GO:0036211 100 0.088
positive regulation of lipase activity GO:0060193 1 0.088
axon development GO:0061564 166 0.086
Fly
regulation of neurogenesis GO:0050767 87 0.086
Mouse Fly
atrioventricular valve formation GO:0003190 3 0.086
eye development GO:0001654 277 0.086
Mouse Fly
cell death GO:0008219 121 0.085
ventricular cardiac myofibril assembly GO:0055005 4 0.084
Mouse
pancreatic d cell differentiation GO:0003311 2 0.083
retinal cell programmed cell death GO:0046666 2 0.083
response to external biotic stimulus GO:0043207 97 0.083
inner ear receptor cell differentiation GO:0060113 29 0.082
forebrain neuron development GO:0021884 7 0.081
catecholamine biosynthetic process GO:0042423 2 0.081
response to peptide GO:1901652 6 0.080
female sex differentiation GO:0046660 4 0.080
regulation of metal ion transport GO:0010959 4 0.079
positive regulation of endothelial cell differentiation GO:0045603 2 0.079
response to organic cyclic compound GO:0014070 51 0.079
response to decreased oxygen levels GO:0036293 25 0.077
toxin metabolic process GO:0009404 1 0.076
regulation of reactive oxygen species metabolic process GO:2000377 2 0.076
urogenital system development GO:0001655 97 0.076
negative regulation of macromolecule metabolic process GO:0010605 76 0.076
Mouse Fly
central nervous system myelination GO:0022010 2 0.076
response to oxygen levels GO:0070482 25 0.076
regulation of transcription involved in cell fate commitment GO:0060850 1 0.076
canonical wnt signaling pathway GO:0060070 48 0.074
regulation of protein binding GO:0043393 3 0.074
regulation of cell differentiation GO:0045595 142 0.074
Mouse Fly
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.074
hemopoiesis GO:0030097 183 0.073
response to other organism GO:0051707 97 0.073
regulation of molecular function GO:0065009 70 0.072
multicellular organism growth GO:0035264 4 0.071
regulation of binding GO:0051098 3 0.070
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.070
osteoclast development GO:0036035 1 0.069
chemical homeostasis GO:0048878 49 0.069
sexual reproduction GO:0019953 36 0.068
Fly
pancreatic d cell development GO:0003324 1 0.068
response to estrogen GO:0043627 27 0.067
gastrulation GO:0007369 208 0.067
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.067
negative regulation of cell migration GO:0030336 17 0.066
cerebellar granular layer formation GO:0021684 3 0.066
Mouse
hypothalamus development GO:0021854 14 0.065
gland morphogenesis GO:0022612 13 0.065
Mouse
vasculogenesis GO:0001570 41 0.064
growth GO:0040007 174 0.064
Mouse
olfactory lobe development GO:0021988 4 0.064
cellular response to endogenous stimulus GO:0071495 68 0.063
cellular response to lipid GO:0071396 39 0.063
positive regulation of secretion by cell GO:1903532 1 0.063
cellular response to nitrogen compound GO:1901699 6 0.062
positive regulation of rna metabolic process GO:0051254 59 0.062
Mouse
reproduction GO:0000003 40 0.061
Fly
exocrine pancreas development GO:0031017 28 0.060
regulation of locomotion GO:0040012 55 0.059
positive regulation of map kinase activity GO:0043406 3 0.059
positive regulation of rna biosynthetic process GO:1902680 57 0.059
Mouse
regulation of membrane potential GO:0042391 23 0.058
response to organonitrogen compound GO:0010243 12 0.058
embryonic heart tube formation GO:0003144 1 0.058
peptide transport GO:0015833 1 0.058
organelle organization GO:0006996 227 0.058
mitochondrion organization GO:0007005 4 0.057
hormone secretion GO:0046879 2 0.057
energy reserve metabolic process GO:0006112 2 0.057
renal system development GO:0072001 94 0.057
carbohydrate homeostasis GO:0033500 1 0.056
negative regulation of apoptotic process GO:0043066 55 0.056
cellular response to external stimulus GO:0071496 2 0.056
ovulation cycle GO:0042698 2 0.056
small molecule metabolic process GO:0044281 77 0.056
response to lipid GO:0033993 60 0.055
neural tube patterning GO:0021532 33 0.055
cellular lipid metabolic process GO:0044255 36 0.055
regulation of nuclease activity GO:0032069 1 0.055
nucleocytoplasmic transport GO:0006913 4 0.055
response to antibiotic GO:0046677 1 0.054
gliogenesis GO:0042063 45 0.054
Fly
mesenchyme development GO:0060485 127 0.054
cardiac muscle tissue development GO:0048738 48 0.054
Mouse
cardiogenic plate morphogenesis GO:0003142 1 0.054
negative regulation of cell communication GO:0010648 96 0.053
specification of organ identity GO:0010092 2 0.053
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.053
protein localization to nucleus GO:0034504 3 0.052
Fly
regulation of muscle contraction GO:0006937 3 0.052
auditory receptor cell development GO:0060117 8 0.052
amide transport GO:0042886 12 0.052
regulation of blood circulation GO:1903522 32 0.052
regulation of fatty acid metabolic process GO:0019217 1 0.051
multicellular organismal reproductive process GO:0048609 35 0.051
Fly
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.050
posterior lateral line neuromast deposition GO:0048922 5 0.050
otolith morphogenesis GO:0032474 8 0.050
chemotaxis GO:0006935 104 0.050
Fly
positive regulation of locomotion GO:0040017 14 0.049
inner ear receptor cell development GO:0060119 20 0.049
regulation of autophagy GO:0010506 3 0.049
astrocyte differentiation GO:0048708 1 0.048
rostrocaudal neural tube patterning GO:0021903 29 0.048
cellular response to steroid hormone stimulus GO:0071383 31 0.047
action potential GO:0001508 19 0.047
ovarian follicle development GO:0001541 2 0.047
cell migration involved in heart development GO:0060973 22 0.046
cardiocyte differentiation GO:0035051 44 0.046
Mouse
stem cell differentiation GO:0048863 117 0.046
Mouse Fly
leukocyte differentiation GO:0002521 25 0.045
cell projection morphogenesis GO:0048858 244 0.045
Fly
regulation of macromolecule biosynthetic process GO:0010556 225 0.045
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.045
positive regulation of transcription dna templated GO:0045893 57 0.045
Mouse
anterior posterior pattern specification GO:0009952 152 0.044
establishment of localization GO:0051234 244 0.044
Fly
negative regulation of programmed cell death GO:0043069 58 0.044
response to oxidative stress GO:0006979 11 0.044
positive regulation of cellular catabolic process GO:0031331 3 0.044
neuromast hair cell development GO:0035675 6 0.043
endothelial cell proliferation GO:0001935 11 0.043
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.043
Mouse Fly
endothelium development GO:0003158 25 0.043
Mouse
response to metal ion GO:0010038 34 0.043
positive regulation of cellular process GO:0048522 201 0.043
Mouse
positive regulation of gene expression GO:0010628 71 0.043
Mouse Fly
motor neuron axon guidance GO:0008045 23 0.042
lymph vessel development GO:0001945 27 0.042
organic acid metabolic process GO:0006082 31 0.042
kidney development GO:0001822 92 0.042
regulation of catalytic activity GO:0050790 55 0.042
positive regulation of cell proliferation GO:0008284 15 0.042
Mouse
regulation of circadian rhythm GO:0042752 4 0.041
cardiac chamber formation GO:0003207 4 0.041
positive regulation of response to external stimulus GO:0032103 9 0.041
eye photoreceptor cell differentiation GO:0001754 45 0.041
Fly
cellular response to extracellular stimulus GO:0031668 2 0.041
pharyngeal muscle development GO:0043282 4 0.040
response to immobilization stress GO:0035902 1 0.040
myeloid cell development GO:0061515 32 0.040
positive regulation of myeloid cell differentiation GO:0045639 2 0.040
cellular response to chemical stimulus GO:0070887 157 0.040
cellular protein metabolic process GO:0044267 129 0.040
positive regulation of cell migration GO:0030335 11 0.040
tissue homeostasis GO:0001894 25 0.040
stem cell proliferation GO:0072089 4 0.039
Fly
regulation of phosphate metabolic process GO:0019220 43 0.039
positive regulation of cell substrate adhesion GO:0010811 1 0.039
aorta development GO:0035904 4 0.039
Mouse
endothelial cell differentiation GO:0045446 20 0.039
Mouse
connective tissue development GO:0061448 99 0.039
monocarboxylic acid metabolic process GO:0032787 17 0.039
venous blood vessel morphogenesis GO:0048845 3 0.039
Mouse
photoreceptor cell fate commitment GO:0046552 1 0.039
Fly
cartilage development GO:0051216 96 0.039
regulation of cellular component movement GO:0051270 55 0.038
axonal fasciculation GO:0007413 11 0.038
cellular component biogenesis GO:0044085 178 0.038
cell matrix adhesion GO:0007160 4 0.038
regulation of mesodermal cell fate specification GO:0042661 9 0.038
cell fate specification involved in pattern specification GO:0060573 3 0.038
regulation of carbohydrate metabolic process GO:0006109 4 0.038
cell maturation GO:0048469 23 0.037
development of primary female sexual characteristics GO:0046545 4 0.037
response to bacterium GO:0009617 58 0.037
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.037
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.036
Mouse
regulation of cellular amine metabolic process GO:0033238 0 0.036
neural crest cell migration GO:0001755 42 0.036
pharyngeal system development GO:0060037 18 0.036
epithelial cell migration GO:0010631 25 0.036
multicellular organismal response to stress GO:0033555 2 0.036
neural tube development GO:0021915 62 0.035
cellular response to nutrient levels GO:0031669 2 0.035
negative regulation of protein phosphorylation GO:0001933 4 0.035
cellular homeostasis GO:0019725 26 0.035
positive regulation of intracellular signal transduction GO:1902533 15 0.035
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.035
hematopoietic progenitor cell differentiation GO:0002244 23 0.035
neuroblast fate commitment GO:0014017 1 0.035
Fly
hypothalamus cell differentiation GO:0021979 4 0.035
positive regulation of catabolic process GO:0009896 4 0.035
muscle cell fate determination GO:0007521 1 0.035
eye photoreceptor cell development GO:0042462 30 0.035
ph reduction GO:0045851 1 0.034
muscle cell differentiation GO:0042692 139 0.034
glial cell differentiation GO:0010001 42 0.034
Fly
phagocytosis GO:0006909 3 0.034
Fly
negative regulation of signal transduction in absence of ligand GO:1901099 1 0.034
cellular response to prostaglandin stimulus GO:0071379 3 0.033
serotonin biosynthetic process GO:0042427 1 0.033
glucocorticoid metabolic process GO:0008211 2 0.033
er nucleus signaling pathway GO:0006984 2 0.033
tissue regeneration GO:0042246 74 0.033
negative regulation of neurogenesis GO:0050768 20 0.032
Fly
cardioblast migration GO:0003260 7 0.032
circulatory system process GO:0003013 87 0.032
multicellular organismal homeostasis GO:0048871 29 0.032
mitotic dna damage checkpoint GO:0044773 4 0.032
striated muscle cell differentiation GO:0051146 129 0.032
positive regulation of secretion GO:0051047 1 0.032
cell surface receptor signaling pathway GO:0007166 325 0.032
cellular response to toxic substance GO:0097237 1 0.031
morphogenesis of an epithelium GO:0002009 333 0.031
Mouse
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.031
forebrain neuron fate commitment GO:0021877 1 0.031
type b pancreatic cell development GO:0003323 4 0.031
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 1 0.031
response to uv GO:0009411 3 0.030
negative regulation of map kinase activity GO:0043407 2 0.030
cell type specific apoptotic process GO:0097285 22 0.030
sprouting angiogenesis GO:0002040 53 0.030
pancreatic a cell differentiation GO:0003310 6 0.030
hepatocyte differentiation GO:0070365 1 0.029
Mouse

prox1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.145
disease of metabolism DOID:0014667 0 0.093
carbohydrate metabolism disease DOID:0050013 0 0.093
acquired metabolic disease DOID:0060158 0 0.093
glucose metabolism disease DOID:4194 0 0.057