Danio rerio

8 known processes

mtf1

metal-regulatory transcription factor 1

(Aliases: MTF-1)

mtf1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular component movement GO:0006928 335 0.047
aging GO:0007568 2 0.043
larval development GO:0002164 2 0.039
positive regulation of transport GO:0051050 2 0.038
positive regulation of cellular component biogenesis GO:0044089 3 0.033
regulation of synapse assembly GO:0051963 3 0.033
cellular protein catabolic process GO:0044257 4 0.032
response to chemical GO:0042221 320 0.032
maintenance of location GO:0051235 4 0.031
cognition GO:0050890 1 0.030
chordate embryonic development GO:0043009 271 0.029
modification dependent protein catabolic process GO:0019941 3 0.029
neuron differentiation GO:0030182 353 0.029
cellular response to external stimulus GO:0071496 2 0.029
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.029
ubiquitin dependent protein catabolic process GO:0006511 3 0.029
proteasomal protein catabolic process GO:0010498 2 0.028
phagocytosis GO:0006909 3 0.028
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.028
generation of neurons GO:0048699 385 0.027
stem cell proliferation GO:0072089 4 0.027
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.027
amine metabolic process GO:0009308 2 0.027
regulation of cellular amine metabolic process GO:0033238 0 0.027
regulation of synapse organization GO:0050807 3 0.026
modification dependent macromolecule catabolic process GO:0043632 3 0.026
cellular response to lipopolysaccharide GO:0071222 3 0.026
response to carbohydrate GO:0009743 3 0.026
cellular ketone metabolic process GO:0042180 11 0.026
cellular amine metabolic process GO:0044106 2 0.025
embryonic organ development GO:0048568 381 0.025
regulation of protein complex assembly GO:0043254 3 0.025
locomotion GO:0040011 313 0.025
multicellular organism growth GO:0035264 4 0.025
cellular response to molecule of bacterial origin GO:0071219 3 0.025
lipid storage GO:0019915 1 0.025
synaptic growth at neuromuscular junction GO:0051124 2 0.025
positive regulation of cell cycle GO:0045787 3 0.024
nuclear transport GO:0051169 4 0.024
cell motility GO:0048870 244 0.024
regulation of cellular amino acid metabolic process GO:0006521 0 0.024
negative regulation of synapse assembly GO:0051964 2 0.024
adult behavior GO:0030534 2 0.023
organonitrogen compound metabolic process GO:1901564 74 0.023
chemosensory behavior GO:0007635 1 0.023
guanosine containing compound metabolic process GO:1901068 4 0.023
response to drug GO:0042493 3 0.023
neurotransmitter transport GO:0006836 2 0.023
cell migration GO:0016477 237 0.023
cellular response to extracellular stimulus GO:0031668 2 0.023
cell part morphogenesis GO:0032990 246 0.022
cell projection organization GO:0030030 284 0.022
stem cell maintenance GO:0019827 4 0.022
regulation of protein transport GO:0051223 3 0.022
actin polymerization or depolymerization GO:0008154 2 0.022
regulation of multicellular organism growth GO:0040014 4 0.022
response to external stimulus GO:0009605 264 0.022
response to alkaloid GO:0043279 2 0.022
regulation of synaptic plasticity GO:0048167 1 0.021
regulation of blood pressure GO:0008217 1 0.021
response to monosaccharide GO:0034284 3 0.021
positive regulation of catabolic process GO:0009896 4 0.021
digestive system development GO:0055123 289 0.021
autophagy GO:0006914 4 0.021
positive regulation of cytoskeleton organization GO:0051495 3 0.021
morphogenesis of an epithelium GO:0002009 333 0.021
cellular response to nutrient levels GO:0031669 2 0.021
synaptic vesicle localization GO:0097479 1 0.020
protein targeting to nucleus GO:0044744 3 0.020
positive regulation of cytokine production GO:0001819 2 0.020
single fertilization GO:0007338 3 0.020
regulation of cytokine production GO:0001817 3 0.020
regulation of reproductive process GO:2000241 4 0.020
response to hexose GO:0009746 3 0.020
cell surface receptor signaling pathway GO:0007166 325 0.020
protein import GO:0017038 3 0.020
establishment of protein localization to organelle GO:0072594 4 0.020
system process GO:0003008 185 0.020
gtp catabolic process GO:0006184 2 0.020
cellular component morphogenesis GO:0032989 336 0.020
tube morphogenesis GO:0035239 349 0.020
guanosine containing compound catabolic process GO:1901069 2 0.020
signal transduction GO:0007165 455 0.020
regulation of cytoplasmic transport GO:1903649 4 0.020
endosomal transport GO:0016197 2 0.019
positive regulation of secretion by cell GO:1903532 1 0.019
protein localization to plasma membrane GO:0072659 1 0.019
regulation of establishment of protein localization GO:0070201 4 0.019
gtp metabolic process GO:0046039 4 0.019
cell morphogenesis GO:0000902 289 0.019
nuclear import GO:0051170 3 0.019
sensory perception of chemical stimulus GO:0007606 3 0.019
oxoacid metabolic process GO:0043436 31 0.019
organic acid metabolic process GO:0006082 31 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.019
regulation of cellular ketone metabolic process GO:0010565 7 0.019
gene expression GO:0010467 252 0.019
neurotransmitter secretion GO:0007269 2 0.019
mitochondrion organization GO:0007005 4 0.019
positive regulation of cellular amine metabolic process GO:0033240 0 0.018
spermatid development GO:0007286 2 0.018
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.018
protein localization to nucleus GO:0034504 3 0.018
cytokinesis GO:0000910 3 0.018
hormone secretion GO:0046879 2 0.018
single organism nuclear import GO:1902593 3 0.018
neuroblast proliferation GO:0007405 2 0.018
cellular response to biotic stimulus GO:0071216 3 0.018
regulation of biological quality GO:0065008 263 0.018
cellular amino acid metabolic process GO:0006520 7 0.018
positive regulation of cellular catabolic process GO:0031331 3 0.018
nucleobase containing compound metabolic process GO:0006139 274 0.018
cell substrate adhesion GO:0031589 4 0.018
cellular component disassembly GO:0022411 1 0.018
response to stress GO:0006950 263 0.018
synaptic vesicle transport GO:0048489 1 0.018
regulation of multicellular organismal process GO:0051239 277 0.018
membrane fusion GO:0061025 2 0.018
negative regulation of protein phosphorylation GO:0001933 4 0.018
peptidyl lysine acetylation GO:0018394 2 0.018
axonogenesis GO:0007409 152 0.017
meiotic cell cycle process GO:1903046 3 0.017
digestive tract morphogenesis GO:0048546 231 0.017
organelle fusion GO:0048284 3 0.017
regulation of stem cell differentiation GO:2000736 4 0.017
rna localization GO:0006403 4 0.017
nucleocytoplasmic transport GO:0006913 4 0.017
cellular macromolecule metabolic process GO:0044260 391 0.017
cell projection morphogenesis GO:0048858 244 0.017
internal protein amino acid acetylation GO:0006475 2 0.017
carboxylic acid metabolic process GO:0019752 22 0.017
protein import into nucleus GO:0006606 3 0.017
fertilization GO:0009566 3 0.017
protein acetylation GO:0006473 2 0.017
positive regulation of protein complex assembly GO:0031334 2 0.017
organelle organization GO:0006996 227 0.017
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.017
adherens junction organization GO:0034332 4 0.017
positive regulation of secretion GO:0051047 1 0.017
single organism membrane fusion GO:0044801 2 0.017
regulation of nucleocytoplasmic transport GO:0046822 2 0.017
brain development GO:0007420 293 0.017
regulation of cell shape GO:0008360 1 0.017
internal peptidyl lysine acetylation GO:0018393 2 0.017
golgi vesicle transport GO:0048193 3 0.017
regulation of stem cell proliferation GO:0072091 2 0.017
regulation of cell activation GO:0050865 1 0.016
ribonucleoside monophosphate catabolic process GO:0009158 4 0.016
compound eye development GO:0048749 2 0.016
central nervous system development GO:0007417 387 0.016
protein polymerization GO:0051258 4 0.016
regulation of neurotransmitter transport GO:0051588 1 0.016
sleep GO:0030431 1 0.016
sensory organ development GO:0007423 393 0.016
regulation of protein catabolic process GO:0042176 1 0.016
response to glucose GO:0009749 3 0.016
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.016
regulation of binding GO:0051098 3 0.016
meiotic nuclear division GO:0007126 4 0.016
neuron development GO:0048666 262 0.016
oocyte anterior posterior axis specification GO:0007314 4 0.016
carbohydrate homeostasis GO:0033500 1 0.016
regulation of nucleotide catabolic process GO:0030811 2 0.016
extrinsic apoptotic signaling pathway GO:0097191 3 0.016
single organism localization GO:1902578 225 0.016
head development GO:0060322 303 0.015
regulation of blood vessel size GO:0050880 2 0.015
exocytosis GO:0006887 1 0.015
biosynthetic process GO:0009058 294 0.015
cytoplasm organization GO:0007028 4 0.015
regulation of neurotransmitter secretion GO:0046928 1 0.015
cellular carbohydrate metabolic process GO:0044262 4 0.015
neuron neuron synaptic transmission GO:0007270 1 0.015
regulation of signal transduction GO:0009966 225 0.015
cellular response to starvation GO:0009267 1 0.015
regulation of nucleoside metabolic process GO:0009118 2 0.015
embryonic organ morphogenesis GO:0048562 274 0.015
organic acid catabolic process GO:0016054 3 0.015
regulation of intracellular protein transport GO:0033157 3 0.015
establishment of protein localization to plasma membrane GO:0090002 1 0.015
regulation of erk1 and erk2 cascade GO:0070372 4 0.015
regulation of mrna processing GO:0050684 3 0.015
stem cell division GO:0017145 1 0.015
regulation of epithelial cell proliferation GO:0050678 3 0.015
anterior posterior pattern specification GO:0009952 152 0.015
regulation of neural precursor cell proliferation GO:2000177 3 0.015
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.015
regulation of purine nucleotide catabolic process GO:0033121 2 0.015
estrogen metabolic process GO:0008210 2 0.015
regulation of meiotic cell cycle GO:0051445 1 0.015
protein complex disassembly GO:0043241 1 0.015
multi organism process GO:0051704 134 0.015
spermatid differentiation GO:0048515 2 0.014
establishment of synaptic vesicle localization GO:0097480 1 0.014
i kappab kinase nf kappab signaling GO:0007249 4 0.014
cellular lipid catabolic process GO:0044242 3 0.014
protein stabilization GO:0050821 2 0.014
protein metabolic process GO:0019538 183 0.014
developmental growth GO:0048589 166 0.014
female gonad development GO:0008585 4 0.014
regulation of protein targeting GO:1903533 2 0.014
response to nutrient GO:0007584 3 0.014
xenobiotic metabolic process GO:0006805 4 0.014
regulation of metal ion transport GO:0010959 4 0.014
negative regulation of catabolic process GO:0009895 3 0.014
inositol lipid mediated signaling GO:0048017 2 0.014
cell morphogenesis involved in differentiation GO:0000904 195 0.014
cellular nitrogen compound biosynthetic process GO:0044271 218 0.014
skeletal system development GO:0001501 181 0.014
intracellular mrna localization GO:0008298 1 0.014
regulation of tube size GO:0035150 2 0.014
macromolecular complex disassembly GO:0032984 1 0.014
organic cyclic compound metabolic process GO:1901360 301 0.014
regulation of dendrite development GO:0050773 3 0.014
leukocyte proliferation GO:0070661 1 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.014
establishment of localization GO:0051234 244 0.014
regulation of mrna splicing via spliceosome GO:0048024 3 0.014
secondary metabolic process GO:0019748 3 0.014
hormone transport GO:0009914 2 0.014
nuclear migration GO:0007097 3 0.014
negative regulation of kinase activity GO:0033673 4 0.014
development of primary female sexual characteristics GO:0046545 4 0.014
embryo development ending in birth or egg hatching GO:0009792 271 0.014
tissue remodeling GO:0048771 4 0.014
nucleoside monophosphate catabolic process GO:0009125 4 0.014
regionalization GO:0003002 274 0.014
protein acylation GO:0043543 3 0.014
synaptic transmission cholinergic GO:0007271 4 0.014
digestive tract development GO:0048565 265 0.013
locomotor rhythm GO:0045475 3 0.013
somatic muscle development GO:0007525 4 0.013
positive regulation of biological process GO:0048518 253 0.013
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.013
cortical cytoskeleton organization GO:0030865 1 0.013
negative regulation of mapk cascade GO:0043409 4 0.013
regulation of signaling GO:0023051 235 0.013
regulation of gtp catabolic process GO:0033124 2 0.013
nucleic acid metabolic process GO:0090304 244 0.013
somatic stem cell maintenance GO:0035019 1 0.013
cell matrix adhesion GO:0007160 4 0.013
carbohydrate biosynthetic process GO:0016051 1 0.013
growth GO:0040007 174 0.013
peptide transport GO:0015833 1 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.013
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.013
epithelial cell differentiation GO:0030855 116 0.013
protein homooligomerization GO:0051260 3 0.013
small molecule metabolic process GO:0044281 77 0.013
lateral inhibition GO:0046331 1 0.013
regulation of protein polymerization GO:0032271 2 0.013
transport GO:0006810 220 0.013
mononuclear cell proliferation GO:0032943 1 0.013
response to uv GO:0009411 3 0.013
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.013
phagocytosis engulfment GO:0006911 1 0.013
cell cycle g1 s phase transition GO:0044843 1 0.013
cellular response to chemical stimulus GO:0070887 157 0.013
female sex differentiation GO:0046660 4 0.013
lipid catabolic process GO:0016042 4 0.013
neuromuscular synaptic transmission GO:0007274 2 0.013
response to organic substance GO:0010033 153 0.013
cellular aromatic compound metabolic process GO:0006725 295 0.013
neuron projection morphogenesis GO:0048812 161 0.013
g1 s transition of mitotic cell cycle GO:0000082 1 0.013
glucose homeostasis GO:0042593 1 0.013
wound healing GO:0042060 90 0.013
single organism organelle organization GO:1902589 199 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.013
regulation of cell projection assembly GO:0060491 4 0.012
maternal determination of anterior posterior axis embryo GO:0008358 4 0.012
neuron projection development GO:0031175 180 0.012
regulation of cell substrate adhesion GO:0010810 1 0.012
regulation of circadian rhythm GO:0042752 4 0.012
response to corticosteroid GO:0031960 1 0.012
atp catabolic process GO:0006200 4 0.012
cytoskeleton dependent cytokinesis GO:0061640 3 0.012
gastrulation GO:0007369 208 0.012
single organism metabolic process GO:0044710 217 0.012
small molecule catabolic process GO:0044282 3 0.012
positive regulation of apoptotic signaling pathway GO:2001235 1 0.012
actin filament polymerization GO:0030041 2 0.012
single organism transport GO:0044765 206 0.012
regulation of protein localization to nucleus GO:1900180 2 0.012
amino acid transport GO:0006865 2 0.012
regulation of metabolic process GO:0019222 359 0.012
regeneration GO:0031099 91 0.012
peptidyl serine modification GO:0018209 2 0.012
negative regulation of stem cell differentiation GO:2000737 2 0.012
positive regulation of nucleoside metabolic process GO:0045979 1 0.012
alcohol biosynthetic process GO:0046165 2 0.012
response to external biotic stimulus GO:0043207 97 0.012
cellular response to radiation GO:0071478 4 0.012
regulation of response to stimulus GO:0048583 269 0.012
phosphatidylinositol mediated signaling GO:0048015 2 0.012
homeostatic process GO:0042592 142 0.012
regulation of protein import into nucleus GO:0042306 2 0.012
regulation of multicellular organismal development GO:2000026 223 0.012
localization of cell GO:0051674 244 0.012
regulation of gtpase activity GO:0043087 2 0.012
actin filament based movement GO:0030048 1 0.012
heterocycle metabolic process GO:0046483 290 0.012
protein dephosphorylation GO:0006470 3 0.012
positive regulation of dna metabolic process GO:0051054 1 0.012
regulation of neuronal synaptic plasticity GO:0048168 1 0.012
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.012
regulation of oocyte development GO:0060281 3 0.012
cell cycle arrest GO:0007050 1 0.012
er to golgi vesicle mediated transport GO:0006888 1 0.012
regulation of dendrite morphogenesis GO:0048814 3 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.012
regulation of carbohydrate metabolic process GO:0006109 4 0.012
membrane invagination GO:0010324 1 0.012
olfactory lobe development GO:0021988 4 0.012
astrocyte differentiation GO:0048708 1 0.012
sequestering of metal ion GO:0051238 3 0.012
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.012
vasculature development GO:0001944 278 0.012
regulation of hormone secretion GO:0046883 2 0.012
response to wounding GO:0009611 116 0.012
b cell activation GO:0042113 2 0.012
positive regulation of synapse assembly GO:0051965 1 0.012
response to amino acid GO:0043200 2 0.012
positive regulation of gtp catabolic process GO:0033126 1 0.012
erk1 and erk2 cascade GO:0070371 4 0.012
translational initiation GO:0006413 3 0.012
endocrine process GO:0050886 2 0.012
protein secretion GO:0009306 1 0.012
cytoskeleton organization GO:0007010 96 0.012
cellular amide metabolic process GO:0043603 4 0.012
response to glucocorticoid GO:0051384 1 0.012
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.012
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.012
cortical actin cytoskeleton organization GO:0030866 1 0.011
positive regulation of cell activation GO:0050867 1 0.011
cellular response to oxygen levels GO:0071453 1 0.011
g protein coupled receptor signaling pathway GO:0007186 74 0.011
negative regulation of protein kinase activity GO:0006469 4 0.011
positive regulation of nucleotide catabolic process GO:0030813 1 0.011
regulation of endocrine process GO:0044060 2 0.011
regulation of developmental process GO:0050793 247 0.011
macroautophagy GO:0016236 1 0.011
organic substance biosynthetic process GO:1901576 289 0.011
regulation of cellular protein catabolic process GO:1903362 1 0.011
rna metabolic process GO:0016070 219 0.011
cellular nitrogen compound metabolic process GO:0034641 290 0.011
blood vessel development GO:0001568 246 0.011
organism emergence from protective structure GO:0071684 4 0.011
production of molecular mediator of immune response GO:0002440 2 0.011
response to other organism GO:0051707 97 0.011
regulation of reactive oxygen species metabolic process GO:2000377 2 0.011
smooth muscle contraction GO:0006939 2 0.011
regulation of inflammatory response GO:0050727 2 0.011
energy reserve metabolic process GO:0006112 2 0.011
regulation of autophagy GO:0010506 3 0.011
determination of left right symmetry GO:0007368 179 0.011
regulation of protein ubiquitination GO:0031396 3 0.011
muscle fiber development GO:0048747 52 0.011
cellular response to organic substance GO:0071310 105 0.011
regulation of systemic arterial blood pressure GO:0003073 1 0.011
sequestering of calcium ion GO:0051208 3 0.011
negative regulation of defense response GO:0031348 2 0.011
positive regulation of protein polymerization GO:0032273 2 0.011
regulation of dna templated transcription elongation GO:0032784 3 0.011
positive regulation of gtpase activity GO:0043547 1 0.011
regulation of nitrogen compound metabolic process GO:0051171 251 0.011
response to topologically incorrect protein GO:0035966 2 0.011
peptidyl threonine phosphorylation GO:0018107 1 0.011
interspecies interaction between organisms GO:0044419 4 0.011
organic cyclic compound biosynthetic process GO:1901362 223 0.011
negative regulation of biological process GO:0048519 304 0.011
meiotic chromosome segregation GO:0045132 3 0.011
nuclear export GO:0051168 1 0.011
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.011
endocrine hormone secretion GO:0060986 2 0.011
negative regulation of cellular catabolic process GO:0031330 3 0.011
regulation of macromolecule metabolic process GO:0060255 317 0.011
negative regulation of intracellular transport GO:0032387 3 0.011
multicellular organismal metabolic process GO:0044236 2 0.011
negative regulation of cellular process GO:0048523 283 0.011
positive regulation of immune effector process GO:0002699 3 0.011
regulation of transporter activity GO:0032409 2 0.010
positive regulation of cellular process GO:0048522 201 0.010
eye development GO:0001654 277 0.010
peptidyl serine phosphorylation GO:0018105 1 0.010
multicellular organismal response to stress GO:0033555 2 0.010
axon development GO:0061564 166 0.010
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.010
post embryonic organ development GO:0048569 4 0.010
neuronal action potential GO:0019228 18 0.010
negative regulation of cytokine production GO:0001818 1 0.010
lymphocyte proliferation GO:0046651 1 0.010
epithelial tube morphogenesis GO:0060562 148 0.010
positive regulation of camp biosynthetic process GO:0030819 2 0.010
multicellular organismal signaling GO:0035637 22 0.010
hemopoiesis GO:0030097 183 0.010
purine nucleoside monophosphate catabolic process GO:0009128 4 0.010
segmentation GO:0035282 97 0.010
positive regulation of myeloid cell differentiation GO:0045639 2 0.010
positive regulation of blood circulation GO:1903524 2 0.010
camera type eye development GO:0043010 222 0.010
regulation of microtubule cytoskeleton organization GO:0070507 3 0.010
striated muscle cell development GO:0055002 108 0.010
regulation of organ growth GO:0046620 3 0.010
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.010
regulation of sequestering of calcium ion GO:0051282 4 0.010
release of sequestered calcium ion into cytosol GO:0051209 3 0.010
cytosolic calcium ion transport GO:0060401 3 0.010
catecholamine metabolic process GO:0006584 2 0.010
negative regulation of sequestering of calcium ion GO:0051283 4 0.010
mitochondrial transport GO:0006839 2 0.010
cellular response to hypoxia GO:0071456 1 0.010
regulation of calcium ion transport GO:0051924 2 0.010
nucleic acid templated transcription GO:0097659 181 0.010
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.010
regulation of myotube differentiation GO:0010830 2 0.010
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.010

mtf1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.034
musculoskeletal system disease DOID:17 0 0.016
nervous system disease DOID:863 0 0.015
disease of metabolism DOID:0014667 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
organ system cancer DOID:0050686 0 0.014
cancer DOID:162 0 0.014
immune system disease DOID:2914 0 0.012
cardiovascular system disease DOID:1287 0 0.011
muscular disease DOID:0080000 0 0.010