Danio rerio

10 known processes

vwc2

von Willebrand factor C domain containing 2

(Aliases: si:dkey-4j1.1)

vwc2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
aging GO:0007568 2 0.056
larval development GO:0002164 2 0.049
neuron differentiation GO:0030182 353 0.042
regulation of multicellular organism growth GO:0040014 4 0.041
multicellular organism growth GO:0035264 4 0.038
cell projection organization GO:0030030 284 0.038
regulation of nitrogen compound metabolic process GO:0051171 251 0.037
response to chemical GO:0042221 320 0.037
central nervous system development GO:0007417 387 0.037
nitrogen compound metabolic process GO:0006807 319 0.037
adult behavior GO:0030534 2 0.035
tube morphogenesis GO:0035239 349 0.035
cellular macromolecule metabolic process GO:0044260 391 0.034
stem cell maintenance GO:0019827 4 0.034
maintenance of location GO:0051235 4 0.034
cell morphogenesis GO:0000902 289 0.033
cellular nitrogen compound metabolic process GO:0034641 290 0.033
generation of neurons GO:0048699 385 0.033
positive regulation of transport GO:0051050 2 0.030
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.030
nucleobase containing compound metabolic process GO:0006139 274 0.030
cell part morphogenesis GO:0032990 246 0.030
sensory organ development GO:0007423 393 0.030
amine metabolic process GO:0009308 2 0.029
cellular component morphogenesis GO:0032989 336 0.029
nucleobase containing compound biosynthetic process GO:0034654 205 0.029
response to external stimulus GO:0009605 264 0.029
heterocycle biosynthetic process GO:0018130 215 0.029
cognition GO:0050890 1 0.029
heterocycle metabolic process GO:0046483 290 0.029
morphogenesis of an epithelium GO:0002009 333 0.028
cellular biosynthetic process GO:0044249 286 0.028
nucleic acid metabolic process GO:0090304 244 0.028
cellular nitrogen compound biosynthetic process GO:0044271 218 0.027
cellular protein catabolic process GO:0044257 4 0.027
ubiquitin dependent protein catabolic process GO:0006511 3 0.027
gene expression GO:0010467 252 0.027
biosynthetic process GO:0009058 294 0.027
cellular component movement GO:0006928 335 0.027
eye development GO:0001654 277 0.027
organic cyclic compound metabolic process GO:1901360 301 0.027
transcription dna templated GO:0006351 181 0.026
brain development GO:0007420 293 0.026
cellular response to external stimulus GO:0071496 2 0.025
regulation of cellular amine metabolic process GO:0033238 0 0.025
macromolecule biosynthetic process GO:0009059 227 0.025
aromatic compound biosynthetic process GO:0019438 217 0.025
cell projection morphogenesis GO:0048858 244 0.025
regulation of rna metabolic process GO:0051252 224 0.025
response to carbohydrate GO:0009743 3 0.025
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.025
embryonic organ development GO:0048568 381 0.025
cellular amine metabolic process GO:0044106 2 0.024
modification dependent protein catabolic process GO:0019941 3 0.024
gtp catabolic process GO:0006184 2 0.024
response to alkaloid GO:0043279 2 0.024
guanosine containing compound metabolic process GO:1901068 4 0.024
head development GO:0060322 303 0.024
regulation of macromolecule metabolic process GO:0060255 317 0.023
nucleic acid templated transcription GO:0097659 181 0.023
cellular macromolecule biosynthetic process GO:0034645 224 0.023
regulation of reproductive process GO:2000241 4 0.023
positive regulation of catabolic process GO:0009896 4 0.023
positive regulation of cellular catabolic process GO:0031331 3 0.023
organic cyclic compound biosynthetic process GO:1901362 223 0.023
phagocytosis GO:0006909 3 0.023
regulation of circadian rhythm GO:0042752 4 0.023
regulation of gene expression GO:0010468 265 0.023
positive regulation of cell cycle GO:0045787 3 0.023
modification dependent macromolecule catabolic process GO:0043632 3 0.022
regulation of multicellular organismal process GO:0051239 277 0.022
signal transduction GO:0007165 455 0.022
amino acid transport GO:0006865 2 0.022
negative regulation of protein phosphorylation GO:0001933 4 0.022
axonogenesis GO:0007409 152 0.022
regulation of cellular biosynthetic process GO:0031326 245 0.022
cellular aromatic compound metabolic process GO:0006725 295 0.022
neuron neuron synaptic transmission GO:0007270 1 0.022
regulation of cellular metabolic process GO:0031323 320 0.022
regulation of synapse assembly GO:0051963 3 0.022
neuron development GO:0048666 262 0.022
stem cell proliferation GO:0072089 4 0.022
neurotransmitter transport GO:0006836 2 0.021
regulation of blood pressure GO:0008217 1 0.021
hormone secretion GO:0046879 2 0.021
regulation of biosynthetic process GO:0009889 250 0.021
compound eye development GO:0048749 2 0.021
rna metabolic process GO:0016070 219 0.021
cellular amide metabolic process GO:0043603 4 0.021
cell surface receptor signaling pathway GO:0007166 325 0.021
sensory organ morphogenesis GO:0090596 200 0.021
lipid storage GO:0019915 1 0.021
digestive tract morphogenesis GO:0048546 231 0.021
regulation of cellular amino acid metabolic process GO:0006521 0 0.021
muscle structure development GO:0061061 196 0.021
organonitrogen compound metabolic process GO:1901564 74 0.021
regulation of developmental process GO:0050793 247 0.021
system process GO:0003008 185 0.021
transcription from rna polymerase ii promoter GO:0006366 80 0.020
regulation of cell activation GO:0050865 1 0.020
regulation of cytokine production GO:0001817 3 0.020
digestive system development GO:0055123 289 0.020
response to drug GO:0042493 3 0.020
locomotion GO:0040011 313 0.020
regulation of metabolic process GO:0019222 359 0.020
regulation of primary metabolic process GO:0080090 311 0.020
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.020
regulation of synapse organization GO:0050807 3 0.020
regulation of neural precursor cell proliferation GO:2000177 3 0.020
regulation of biological quality GO:0065008 263 0.020
camera type eye development GO:0043010 222 0.020
negative regulation of protein kinase activity GO:0006469 4 0.020
small molecule metabolic process GO:0044281 77 0.020
olfactory lobe development GO:0021988 4 0.020
regulation of establishment of protein localization GO:0070201 4 0.019
specification of symmetry GO:0009799 204 0.019
hormone transport GO:0009914 2 0.019
chemosensory behavior GO:0007635 1 0.019
organic substance biosynthetic process GO:1901576 289 0.019
neurotransmitter secretion GO:0007269 2 0.019
regulation of protein catabolic process GO:0042176 1 0.019
regulation of mrna processing GO:0050684 3 0.019
endocrine process GO:0050886 2 0.019
establishment of protein localization to organelle GO:0072594 4 0.019
negative regulation of kinase activity GO:0033673 4 0.019
regionalization GO:0003002 274 0.019
regulation of tube size GO:0035150 2 0.019
cellular response to extracellular stimulus GO:0031668 2 0.019
regulation of binding GO:0051098 3 0.018
response to hexose GO:0009746 3 0.018
proteasomal protein catabolic process GO:0010498 2 0.018
response to glucose GO:0009749 3 0.018
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.018
cellular ketone metabolic process GO:0042180 11 0.018
female sex differentiation GO:0046660 4 0.018
cell morphogenesis involved in differentiation GO:0000904 195 0.018
female gonad development GO:0008585 4 0.018
chemotaxis GO:0006935 104 0.018
regulation of synaptic plasticity GO:0048167 1 0.018
olfactory bulb development GO:0021772 4 0.018
single organism metabolic process GO:0044710 217 0.018
development of primary female sexual characteristics GO:0046545 4 0.018
regulation of macromolecule biosynthetic process GO:0010556 225 0.018
meiotic cell cycle process GO:1903046 3 0.018
sleep GO:0030431 1 0.018
gtp metabolic process GO:0046039 4 0.018
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.018
positive regulation of cellular component biogenesis GO:0044089 3 0.018
regulation of nucleic acid templated transcription GO:1903506 213 0.017
regulation of neurotransmitter transport GO:0051588 1 0.017
regulation of hormone secretion GO:0046883 2 0.017
regulation of endocrine process GO:0044060 2 0.017
peptide metabolic process GO:0006518 1 0.017
synaptic growth at neuromuscular junction GO:0051124 2 0.017
blood vessel development GO:0001568 246 0.017
leukocyte proliferation GO:0070661 1 0.017
dicarboxylic acid transport GO:0006835 1 0.017
gastrulation GO:0007369 208 0.017
peptide transport GO:0015833 1 0.017
immune system process GO:0002376 241 0.017
determination of left right symmetry GO:0007368 179 0.017
regulation of inflammatory response GO:0050727 2 0.017
nucleocytoplasmic transport GO:0006913 4 0.017
regulation of sequestering of calcium ion GO:0051282 4 0.017
regulation of ion transmembrane transporter activity GO:0032412 2 0.017
sequestering of metal ion GO:0051238 3 0.017
regulation of cellular ketone metabolic process GO:0010565 7 0.017
meiotic nuclear division GO:0007126 4 0.017
response to organic substance GO:0010033 153 0.017
guanosine containing compound catabolic process GO:1901069 2 0.017
response to amphetamine GO:0001975 1 0.017
actin polymerization or depolymerization GO:0008154 2 0.016
rna biosynthetic process GO:0032774 181 0.016
oxoacid metabolic process GO:0043436 31 0.016
regulation of sodium ion transport GO:0002028 2 0.016
nuclear transport GO:0051169 4 0.016
regulation of transcription dna templated GO:0006355 213 0.016
embryonic organ morphogenesis GO:0048562 274 0.016
determination of bilateral symmetry GO:0009855 204 0.016
regulation of metal ion transport GO:0010959 4 0.016
heart development GO:0007507 313 0.016
synaptic vesicle localization GO:0097479 1 0.016
mitochondrion organization GO:0007005 4 0.016
positive regulation of cellular amine metabolic process GO:0033240 0 0.016
neuron projection development GO:0031175 180 0.016
neuron projection morphogenesis GO:0048812 161 0.016
production of molecular mediator of immune response GO:0002440 2 0.016
regulation of rna biosynthetic process GO:2001141 213 0.016
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.016
positive regulation of protein complex assembly GO:0031334 2 0.016
protein import GO:0017038 3 0.015
protein localization to plasma membrane GO:0072659 1 0.015
protein polymerization GO:0051258 4 0.015
regulation of protein complex assembly GO:0043254 3 0.015
protein acetylation GO:0006473 2 0.015
positive regulation of immune effector process GO:0002699 3 0.015
regulation of signaling GO:0023051 235 0.015
peptidyl lysine acetylation GO:0018394 2 0.015
digestive tract development GO:0048565 265 0.015
protein targeting to nucleus GO:0044744 3 0.015
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.015
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.015
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.015
regulation of multicellular organismal development GO:2000026 223 0.015
organic acid metabolic process GO:0006082 31 0.015
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.015
adherens junction organization GO:0034332 4 0.015
regulation of meiotic cell cycle GO:0051445 1 0.015
dorsal ventral pattern formation GO:0009953 125 0.015
rna localization GO:0006403 4 0.015
axon development GO:0061564 166 0.015
locomotor rhythm GO:0045475 3 0.015
growth GO:0040007 174 0.015
regulation of protein ubiquitination GO:0031396 3 0.015
regulation of transmembrane transporter activity GO:0022898 2 0.015
protein import into nucleus GO:0006606 3 0.015
positive regulation of cytoskeleton organization GO:0051495 3 0.015
lateral inhibition GO:0046331 1 0.015
sequestering of calcium ion GO:0051208 3 0.015
exocytosis GO:0006887 1 0.015
renal system development GO:0072001 94 0.015
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.015
localization of cell GO:0051674 244 0.014
response to amine GO:0014075 1 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.014
regulation of response to stimulus GO:0048583 269 0.014
negative regulation of sequestering of calcium ion GO:0051283 4 0.014
positive regulation of biological process GO:0048518 253 0.014
regulation of systemic arterial blood pressure GO:0003073 1 0.014
glial cell migration GO:0008347 3 0.014
vasculature development GO:0001944 278 0.014
regulation of signal transduction GO:0009966 225 0.014
regulation of production of molecular mediator of immune response GO:0002700 1 0.014
organonitrogen compound biosynthetic process GO:1901566 47 0.014
cell motility GO:0048870 244 0.014
internal peptidyl lysine acetylation GO:0018393 2 0.014
regulation of cytoplasmic transport GO:1903649 4 0.014
antimicrobial humoral response GO:0019730 2 0.014
cellular component disassembly GO:0022411 1 0.014
hemopoiesis GO:0030097 183 0.014
negative regulation of map kinase activity GO:0043407 2 0.014
negative regulation of biological process GO:0048519 304 0.014
synaptic target recognition GO:0008039 1 0.014
regulation of carbohydrate metabolic process GO:0006109 4 0.014
golgi vesicle transport GO:0048193 3 0.014
cellular response to chemical stimulus GO:0070887 157 0.014
germ line stem cell maintenance GO:0030718 2 0.014
cellular amino acid metabolic process GO:0006520 7 0.014
autophagy GO:0006914 4 0.014
cellular response to biotic stimulus GO:0071216 3 0.014
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.014
cellular response to nutrient levels GO:0031669 2 0.014
post embryonic organ development GO:0048569 4 0.014
regulation of nucleoside metabolic process GO:0009118 2 0.014
carbohydrate biosynthetic process GO:0016051 1 0.014
somatic muscle development GO:0007525 4 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.014
interspecies interaction between organisms GO:0044419 4 0.014
regulation of transporter activity GO:0032409 2 0.014
b cell activation GO:0042113 2 0.014
response to stress GO:0006950 263 0.013
peptidyl serine modification GO:0018209 2 0.013
regulation of nucleotide catabolic process GO:0030811 2 0.013
carboxylic acid metabolic process GO:0019752 22 0.013
organelle organization GO:0006996 227 0.013
membrane invagination GO:0010324 1 0.013
transport GO:0006810 220 0.013
tissue remodeling GO:0048771 4 0.013
synaptic vesicle transport GO:0048489 1 0.013
nuclear import GO:0051170 3 0.013
regulation of purine nucleotide catabolic process GO:0033121 2 0.013
cellular response to starvation GO:0009267 1 0.013
immune system development GO:0002520 191 0.013
neuroblast proliferation GO:0007405 2 0.013
cytokinesis GO:0000910 3 0.013
ion transport GO:0006811 114 0.013
regulation of blood vessel size GO:0050880 2 0.013
actin filament polymerization GO:0030041 2 0.013
regulation of neuronal synaptic plasticity GO:0048168 1 0.013
internal protein amino acid acetylation GO:0006475 2 0.013
ribonucleoside monophosphate catabolic process GO:0009158 4 0.013
regulation of response to biotic stimulus GO:0002831 2 0.013
response to uv GO:0009411 3 0.013
protein homooligomerization GO:0051260 3 0.013
catechol containing compound metabolic process GO:0009712 2 0.013
hematopoietic or lymphoid organ development GO:0048534 191 0.013
pole plasm assembly GO:0007315 4 0.013
positive regulation of histone modification GO:0031058 1 0.013
single organism nuclear import GO:1902593 3 0.013
startle response GO:0001964 4 0.013
regulation of cell shape GO:0008360 1 0.013
positive regulation of cytokine production GO:0001819 2 0.013
cellular response to molecule of bacterial origin GO:0071219 3 0.013
establishment of synaptic vesicle localization GO:0097480 1 0.013
ameboidal type cell migration GO:0001667 143 0.013
spermatid differentiation GO:0048515 2 0.013
establishment of localization GO:0051234 244 0.013
phagocytosis engulfment GO:0006911 1 0.013
carbohydrate homeostasis GO:0033500 1 0.013
protein acylation GO:0043543 3 0.012
regulation of protein polymerization GO:0032271 2 0.012
maternal determination of anterior posterior axis embryo GO:0008358 4 0.012
lymphocyte proliferation GO:0046651 1 0.012
axon guidance GO:0007411 86 0.012
determination of heart left right asymmetry GO:0061371 117 0.012
regulation of cell differentiation GO:0045595 142 0.012
extrinsic apoptotic signaling pathway GO:0097191 3 0.012
intracellular mrna localization GO:0008298 1 0.012
response to food GO:0032094 1 0.012
positive regulation of secretion GO:0051047 1 0.012
regulation of cell communication GO:0010646 232 0.012
cellular response to lipopolysaccharide GO:0071222 3 0.012
single organism organelle organization GO:1902589 199 0.012
positive regulation of map kinase activity GO:0043406 3 0.012
positive regulation of nucleotide catabolic process GO:0030813 1 0.012
muscle cell development GO:0055001 115 0.012
regulation of calcium ion transport GO:0051924 2 0.012
positive regulation of chromosome organization GO:2001252 1 0.012
cytoplasm organization GO:0007028 4 0.012
positive regulation of cell activation GO:0050867 1 0.012
lipid catabolic process GO:0016042 4 0.012
response to nutrient GO:0007584 3 0.012
cell migration GO:0016477 237 0.012
negative regulation of catabolic process GO:0009895 3 0.012
regulation of cell projection assembly GO:0060491 4 0.012
positive regulation of nucleoside metabolic process GO:0045979 1 0.012
ion transmembrane transport GO:0034220 91 0.012
inositol lipid mediated signaling GO:0048017 2 0.012
mononuclear cell proliferation GO:0032943 1 0.012
protein localization to nucleus GO:0034504 3 0.012
epithelial tube morphogenesis GO:0060562 148 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.012
response to topologically incorrect protein GO:0035966 2 0.012
regulation of anatomical structure morphogenesis GO:0022603 130 0.012
negative regulation of cellular process GO:0048523 283 0.012
positive regulation of dna metabolic process GO:0051054 1 0.012
embryonic heart tube development GO:0035050 133 0.012
cellular carbohydrate metabolic process GO:0044262 4 0.012
positive regulation of cell adhesion GO:0045785 1 0.012
protein complex disassembly GO:0043241 1 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.011
regulation of gtpase activity GO:0043087 2 0.011
negative regulation of secretion by cell GO:1903531 2 0.011
glucose homeostasis GO:0042593 1 0.011
negative regulation of secretion GO:0051048 2 0.011
response to monosaccharide GO:0034284 3 0.011
single fertilization GO:0007338 3 0.011
regulation of gtp catabolic process GO:0033124 2 0.011
regulation of protein transport GO:0051223 3 0.011
embryonic heart tube morphogenesis GO:0003143 108 0.011
cell substrate adhesion GO:0031589 4 0.011
eye morphogenesis GO:0048592 144 0.011
developmental growth GO:0048589 166 0.011
secondary metabolic process GO:0019748 3 0.011
sensory perception of chemical stimulus GO:0007606 3 0.011
cellular protein metabolic process GO:0044267 129 0.011
spermatid development GO:0007286 2 0.011
meiotic chromosome segregation GO:0045132 3 0.011
positive regulation of blood circulation GO:1903524 2 0.011
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.011
atp catabolic process GO:0006200 4 0.011
positive regulation of chromatin modification GO:1903310 1 0.011
blood vessel morphogenesis GO:0048514 216 0.011
macromolecular complex disassembly GO:0032984 1 0.011
catecholamine metabolic process GO:0006584 2 0.011
protein dephosphorylation GO:0006470 3 0.011
homeostatic process GO:0042592 142 0.011
regulation of dendrite development GO:0050773 3 0.011
regulation of muscle contraction GO:0006937 3 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.011
regulation of neurogenesis GO:0050767 87 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.011
mesenchyme development GO:0060485 127 0.011
protein stabilization GO:0050821 2 0.011
convergent extension GO:0060026 118 0.011
protein secretion GO:0009306 1 0.011
protein heterooligomerization GO:0051291 1 0.011
response to wounding GO:0009611 116 0.011
regulation of reactive oxygen species metabolic process GO:2000377 2 0.011
heart looping GO:0001947 94 0.011
positive regulation of reproductive process GO:2000243 2 0.011
negative regulation of protein transport GO:0051224 3 0.011
cellular response to xenobiotic stimulus GO:0071466 35 0.011
spindle assembly GO:0051225 2 0.011
actin filament based movement GO:0030048 1 0.011
cytoskeleton dependent cytokinesis GO:0061640 3 0.011
negative regulation of synapse assembly GO:0051964 2 0.011
blood circulation GO:0008015 87 0.011
fertilization GO:0009566 3 0.011
regulation of microtubule cytoskeleton organization GO:0070507 3 0.011
peptidyl threonine phosphorylation GO:0018107 1 0.011
epithelial cell differentiation GO:0030855 116 0.011
neuron projection guidance GO:0097485 86 0.010
regulation of intracellular protein transport GO:0033157 3 0.010
response to xenobiotic stimulus GO:0009410 45 0.010
regulation of protein targeting GO:1903533 2 0.010
transmembrane transport GO:0055085 120 0.010
chordate embryonic development GO:0043009 271 0.010
negative regulation of mapk cascade GO:0043409 4 0.010
calcium ion transport into cytosol GO:0060402 3 0.010
mesoderm development GO:0007498 88 0.010
response to external biotic stimulus GO:0043207 97 0.010
regulation of ph GO:0006885 3 0.010
response to other organism GO:0051707 97 0.010
regulation of cell development GO:0060284 100 0.010
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.010
regulation of stem cell differentiation GO:2000736 4 0.010
cellular response to radiation GO:0071478 4 0.010
regulation of protein depolymerization GO:1901879 1 0.010
positive regulation of protein polymerization GO:0032273 2 0.010
outflow tract morphogenesis GO:0003151 1 0.010
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.010
skeletal system morphogenesis GO:0048705 102 0.010
muscle organ development GO:0007517 101 0.010
retina development in camera type eye GO:0060041 146 0.010
negative regulation of cytokine production GO:0001818 1 0.010

vwc2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.031
musculoskeletal system disease DOID:17 0 0.015
disease of cellular proliferation DOID:14566 0 0.014
cancer DOID:162 0 0.014
organ system cancer DOID:0050686 0 0.014
nervous system disease DOID:863 0 0.014
disease of metabolism DOID:0014667 0 0.013
inherited metabolic disorder DOID:655 0 0.013
cardiovascular system disease DOID:1287 0 0.012
immune system disease DOID:2914 0 0.010
connective tissue disease DOID:65 0 0.010