Danio rerio

18 known processes

ttc21b

tetratricopeptide repeat domain 21B

(Aliases: sb:cb947)

ttc21b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
microtubule based movement GO:0007018 33 0.968
Mouse
cilium organization GO:0044782 71 0.878
Mouse
nonmotile primary cilium assembly GO:0035058 2 0.692
cilium assembly GO:0042384 58 0.626
intraciliary transport GO:0042073 7 0.618
Mouse
cell morphogenesis GO:0000902 289 0.484
Mouse
cell projection assembly GO:0030031 64 0.481
cell projection morphogenesis GO:0048858 244 0.446
Mouse
cilium morphogenesis GO:0060271 85 0.377
Mouse
single organism organelle organization GO:1902589 199 0.363
Mouse
cellular component biogenesis GO:0044085 178 0.353
cellular component morphogenesis GO:0032989 336 0.338
Mouse
convergent extension GO:0060026 118 0.322
cilium movement GO:0003341 26 0.317
cellular component movement GO:0006928 335 0.301
Mouse
morphogenesis of an epithelium GO:0002009 333 0.298
cell projection organization GO:0030030 284 0.281
Mouse
cellular component assembly involved in morphogenesis GO:0010927 107 0.272
signal transduction GO:0007165 455 0.245
Mouse
cell part morphogenesis GO:0032990 246 0.216
Mouse
determination of heart left right asymmetry GO:0061371 117 0.181
locomotion GO:0040011 313 0.176
single organism transport GO:0044765 206 0.165
Mouse
organelle assembly GO:0070925 110 0.159
determination of bilateral symmetry GO:0009855 204 0.153
microtubule based process GO:0007017 60 0.135
Mouse
epithelial cilium movement GO:0003351 15 0.134
tube morphogenesis GO:0035239 349 0.132
heart looping GO:0001947 94 0.131
heart development GO:0007507 313 0.113
cellular localization GO:0051641 97 0.106
Mouse
gastrulation GO:0007369 208 0.106
determination of left right symmetry GO:0007368 179 0.104
embryonic heart tube development GO:0035050 133 0.102
cell surface receptor signaling pathway GO:0007166 325 0.100
Mouse
specification of symmetry GO:0009799 204 0.094
digestive tract morphogenesis GO:0048546 231 0.093
cellular component assembly GO:0022607 170 0.093
heart morphogenesis GO:0003007 156 0.089
embryonic organ development GO:0048568 381 0.087
epithelial tube morphogenesis GO:0060562 148 0.083
organelle organization GO:0006996 227 0.082
Mouse
primary neural tube formation GO:0014020 1 0.081
transport GO:0006810 220 0.081
Mouse
single organism localization GO:1902578 225 0.080
Mouse
digestive system development GO:0055123 289 0.079
meiotic nuclear division GO:0007126 4 0.077
response to chemical GO:0042221 320 0.076
retina homeostasis GO:0001895 12 0.075
embryonic organ morphogenesis GO:0048562 274 0.074
regulation of tube size GO:0035150 2 0.071
larval development GO:0002164 2 0.071
embryonic heart tube morphogenesis GO:0003143 108 0.070
urogenital system development GO:0001655 97 0.068
negative regulation of epithelial cell proliferation GO:0050680 1 0.066
convergent extension involved in gastrulation GO:0060027 71 0.066
regulation of epithelial cell proliferation GO:0050678 3 0.065
negative regulation of cellular process GO:0048523 283 0.062
regulation of response to stimulus GO:0048583 269 0.062
Mouse
protein modification process GO:0036211 100 0.060
regulation of signal transduction GO:0009966 225 0.057
Mouse
cellular protein modification process GO:0006464 100 0.055
regulation of signaling GO:0023051 235 0.054
Mouse
aging GO:0007568 2 0.054
kidney development GO:0001822 92 0.053
epithelial cilium movement involved in determination of left right asymmetry GO:0060287 8 0.053
regulation of blood vessel size GO:0050880 2 0.052
digestive tract development GO:0048565 265 0.052
positive regulation of cellular component biogenesis GO:0044089 3 0.051
intracellular transport GO:0046907 32 0.051
Mouse
negative regulation of biological process GO:0048519 304 0.050
cell motility GO:0048870 244 0.050
lipid storage GO:0019915 1 0.050
axoneme assembly GO:0035082 9 0.050
cytoskeleton dependent intracellular transport GO:0030705 10 0.049
Mouse
localization of cell GO:0051674 244 0.048
response to stress GO:0006950 263 0.047
smooth muscle contraction GO:0006939 2 0.045
spindle assembly GO:0051225 2 0.043
modification dependent protein catabolic process GO:0019941 3 0.042
left right pattern formation GO:0060972 19 0.041
pronephros morphogenesis GO:0072114 14 0.041
pronephros development GO:0048793 69 0.041
regulation of cellular response to growth factor stimulus GO:0090287 35 0.039
maintenance of location GO:0051235 4 0.039
cell migration GO:0016477 237 0.038
ameboidal type cell migration GO:0001667 143 0.038
response to xenobiotic stimulus GO:0009410 45 0.037
smoothened signaling pathway GO:0007224 30 0.036
Mouse
tube closure GO:0060606 1 0.036
positive regulation of jun kinase activity GO:0043507 2 0.035
macromolecule modification GO:0043412 111 0.035
cell proliferation GO:0008283 80 0.034
cellular pigmentation GO:0033059 30 0.033
regulation of cytokine production GO:0001817 3 0.032
regulation of cell communication GO:0010646 232 0.031
Mouse
renal system development GO:0072001 94 0.031
cellular component disassembly GO:0022411 1 0.031
somite development GO:0061053 96 0.030
cytoskeleton organization GO:0007010 96 0.030
multicellular organism growth GO:0035264 4 0.030
photoreceptor cell morphogenesis GO:0008594 1 0.030
tor signaling GO:0031929 7 0.030
cellular protein catabolic process GO:0044257 4 0.029
centrosome duplication GO:0051298 1 0.029
cell morphogenesis involved in differentiation GO:0000904 195 0.029
microtubule based transport GO:0010970 10 0.029
Mouse
centrosome organization GO:0051297 1 0.028
modification dependent macromolecule catabolic process GO:0043632 3 0.028
cell migration involved in gastrulation GO:0042074 79 0.028
regulation of establishment of protein localization GO:0070201 4 0.028
blood circulation GO:0008015 87 0.028
compound eye development GO:0048749 2 0.027
regionalization GO:0003002 274 0.026
Mouse
negative regulation of dna metabolic process GO:0051053 4 0.026
chordate embryonic development GO:0043009 271 0.026
meiotic cell cycle process GO:1903046 3 0.026
positive regulation of transport GO:0051050 2 0.026
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.026
cellular macromolecule metabolic process GO:0044260 391 0.025
establishment of localization GO:0051234 244 0.025
Mouse
photoreceptor cell development GO:0042461 40 0.025
epithelial cell morphogenesis GO:0003382 2 0.025
organic cyclic compound biosynthetic process GO:1901362 223 0.025
regulation of metabolic process GO:0019222 359 0.024
heart process GO:0003015 71 0.024
intracellular signal transduction GO:0035556 85 0.024
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.023
regulation of protein catabolic process GO:0042176 1 0.023
dorsal ventral pattern formation GO:0009953 125 0.023
Mouse
macromolecular complex disassembly GO:0032984 1 0.023
protein complex disassembly GO:0043241 1 0.023
negative regulation of signal transduction GO:0009968 94 0.022
establishment of localization in cell GO:0051649 77 0.021
Mouse
negative regulation of cellular catabolic process GO:0031330 3 0.021
spindle assembly involved in mitosis GO:0090307 1 0.021
gene expression GO:0010467 252 0.021
macromolecular complex subunit organization GO:0043933 74 0.021
regulation of protein transport GO:0051223 3 0.021
protein metabolic process GO:0019538 183 0.021
ether metabolic process GO:0018904 1 0.021
regulation of blood pressure GO:0008217 1 0.021
system process GO:0003008 185 0.021
cellular nitrogen compound biosynthetic process GO:0044271 218 0.021
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.021
tissue homeostasis GO:0001894 25 0.020
kupffer s vesicle development GO:0070121 50 0.020
photoreceptor cell differentiation GO:0046530 55 0.020
chemosensory behavior GO:0007635 1 0.020
negative regulation of stem cell differentiation GO:2000737 2 0.020
response to external stimulus GO:0009605 264 0.020
regulation of multicellular organism growth GO:0040014 4 0.020
homeostatic process GO:0042592 142 0.020
taxis GO:0042330 109 0.020
pigment granule aggregation in cell center GO:0051877 8 0.020
cellular nitrogen compound metabolic process GO:0034641 290 0.019
circulatory system process GO:0003013 87 0.019
regulation of cell shape GO:0008360 1 0.019
cellular response to extracellular stimulus GO:0031668 2 0.019
cell proliferation in forebrain GO:0021846 3 0.019
positive regulation of biological process GO:0048518 253 0.019
camera type eye development GO:0043010 222 0.019
angiogenesis GO:0001525 158 0.019
nitrogen compound metabolic process GO:0006807 319 0.018
developmental growth GO:0048589 166 0.018
regulation of tor signaling GO:0032006 7 0.018
growth GO:0040007 174 0.018
pigmentation GO:0043473 85 0.018
adult behavior GO:0030534 2 0.018
secondary metabolic process GO:0019748 3 0.018
pronephric duct development GO:0039022 13 0.018
stem cell proliferation GO:0072089 4 0.018
regulation of biological quality GO:0065008 263 0.018
vasculature development GO:0001944 278 0.017
regulation of multicellular organismal process GO:0051239 277 0.017
male meiosis GO:0007140 2 0.017
negative regulation of catabolic process GO:0009895 3 0.017
immune system process GO:0002376 241 0.017
regulation of intracellular signal transduction GO:1902531 57 0.017
single organism intracellular transport GO:1902582 25 0.017
Mouse
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.017
regulation of gtp catabolic process GO:0033124 2 0.016
phagocytosis GO:0006909 3 0.016
regulation of microtubule cytoskeleton organization GO:0070507 3 0.016
heterocycle biosynthetic process GO:0018130 215 0.016
cellular response to chemical stimulus GO:0070887 157 0.016
regulation of protein ubiquitination GO:0031396 3 0.016
neuron development GO:0048666 262 0.016
cardiac atrium development GO:0003230 4 0.016
aromatic compound biosynthetic process GO:0019438 217 0.016
head development GO:0060322 303 0.016
Mouse
negative regulation of response to stimulus GO:0048585 104 0.015
positive regulation of cytoskeleton organization GO:0051495 3 0.015
female meiotic division GO:0007143 2 0.015
regulation of muscle contraction GO:0006937 3 0.015
organonitrogen compound metabolic process GO:1901564 74 0.015
cytokinesis GO:0000910 3 0.015
regulation of nucleotide catabolic process GO:0030811 2 0.015
rna transport GO:0050658 2 0.015
regulation of reproductive process GO:2000241 4 0.015
embryo development ending in birth or egg hatching GO:0009792 271 0.015
skeletal system development GO:0001501 181 0.015
negative regulation of cell communication GO:0010648 96 0.015
nucleocytoplasmic transport GO:0006913 4 0.015
actin filament polymerization GO:0030041 2 0.015
renal system process involved in regulation of systemic arterial blood pressure GO:0003071 1 0.015
mesenchyme development GO:0060485 127 0.015
protein k48 linked ubiquitination GO:0070936 1 0.015
cellular response to radiation GO:0071478 4 0.015
regulation of nucleoside metabolic process GO:0009118 2 0.014
chemotaxis GO:0006935 104 0.014
regulation of dna recombination GO:0000018 2 0.014
regulation of purine nucleotide catabolic process GO:0033121 2 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.014
neural tube development GO:0021915 62 0.014
oxoacid metabolic process GO:0043436 31 0.014
regulation of mrna splicing via spliceosome GO:0048024 3 0.014
cytoskeleton dependent cytokinesis GO:0061640 3 0.014
multicellular organismal homeostasis GO:0048871 29 0.014
lymphocyte proliferation GO:0046651 1 0.014
positive regulation of cell activation GO:0050867 1 0.014
negative regulation of wnt signaling pathway GO:0030178 30 0.014
peptidyl lysine acetylation GO:0018394 2 0.014
protein polymerization GO:0051258 4 0.014
organic acid metabolic process GO:0006082 31 0.013
positive regulation of multi organism process GO:0043902 3 0.013
nephron epithelium morphogenesis GO:0072088 1 0.013
macromolecule localization GO:0033036 54 0.013
long chain fatty acid metabolic process GO:0001676 1 0.013
b cell mediated immunity GO:0019724 3 0.013
cellular response to organic substance GO:0071310 105 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.013
intracellular estrogen receptor signaling pathway GO:0030520 3 0.013
gtp catabolic process GO:0006184 2 0.013
cellular amino acid metabolic process GO:0006520 7 0.013
positive regulation of jnk cascade GO:0046330 3 0.013
generation of neurons GO:0048699 385 0.013
developmental growth involved in morphogenesis GO:0060560 86 0.013
nephric duct development GO:0072176 13 0.013
cellular response to starvation GO:0009267 1 0.013
regulation of rho protein signal transduction GO:0035023 2 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.013
chromatin modification GO:0016568 21 0.013
negative regulation of signaling GO:0023057 96 0.012
regulation of hormone secretion GO:0046883 2 0.012
microtubule bundle formation GO:0001578 9 0.012
amine metabolic process GO:0009308 2 0.012
cellular amine metabolic process GO:0044106 2 0.012
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.012
b cell activation GO:0042113 2 0.012
regulation of circadian rhythm GO:0042752 4 0.012
cellular response to endogenous stimulus GO:0071495 68 0.012
regulation of gtpase activity GO:0043087 2 0.012
regulation of dna replication GO:0006275 3 0.012
central nervous system development GO:0007417 387 0.012
Mouse
notch signaling pathway GO:0007219 35 0.012
regulation of cellular amine metabolic process GO:0033238 0 0.012
establishment of protein localization to organelle GO:0072594 4 0.012
mononuclear cell proliferation GO:0032943 1 0.012
sensory organ development GO:0007423 393 0.012
cilium or flagellum dependent cell motility GO:0001539 4 0.012
heart jogging GO:0003146 40 0.012
sensory perception of chemical stimulus GO:0007606 3 0.012
melanosome localization GO:0032400 21 0.012
neuroblast proliferation GO:0007405 2 0.012
anatomical structure homeostasis GO:0060249 36 0.012
positive regulation of cyclin dependent protein serine threonine kinase activity GO:0045737 1 0.011
synaptic growth at neuromuscular junction GO:0051124 2 0.011
protein phosphorylation GO:0006468 47 0.011
regulation of nitrogen compound metabolic process GO:0051171 251 0.011
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.011
guanosine containing compound metabolic process GO:1901068 4 0.011
microtubule organizing center organization GO:0031023 1 0.011
carboxylic acid metabolic process GO:0019752 22 0.011
neuron differentiation GO:0030182 353 0.011
negative regulation of ras protein signal transduction GO:0046580 1 0.011
regulation of anatomical structure morphogenesis GO:0022603 130 0.011
connective tissue development GO:0061448 99 0.011
regulation of stem cell differentiation GO:2000736 4 0.011
establishment of epithelial cell polarity GO:0090162 2 0.011
response to organic substance GO:0010033 153 0.011
guanosine containing compound catabolic process GO:1901069 2 0.011
photoreceptor cell fate specification GO:0043704 1 0.011
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.011
regulation of cell proliferation GO:0042127 37 0.011
leukocyte proliferation GO:0070661 1 0.011
positive regulation of catabolic process GO:0009896 4 0.011
ribonucleoside monophosphate catabolic process GO:0009158 4 0.011
rna metabolic process GO:0016070 219 0.011
skin development GO:0043588 54 0.011
single organism metabolic process GO:0044710 217 0.011
protein localization GO:0008104 40 0.010
protein secretion GO:0009306 1 0.010
nucleic acid metabolic process GO:0090304 244 0.010
specification of axis polarity GO:0065001 4 0.010
axonogenesis GO:0007409 152 0.010
anatomical structure arrangement GO:0048532 2 0.010
alternative mrna splicing via spliceosome GO:0000380 1 0.010
g2 dna damage checkpoint GO:0031572 3 0.010
response to osmotic stress GO:0006970 11 0.010
establishment of apical basal cell polarity GO:0035089 2 0.010
forebrain development GO:0030900 96 0.010
Mouse
protein localization to plasma membrane GO:0072659 1 0.010
phosphorylation GO:0016310 69 0.010
internal peptidyl lysine acetylation GO:0018393 2 0.010
mesenchymal cell development GO:0014031 78 0.010
negative regulation of cytokine mediated signaling pathway GO:0001960 2 0.010
positive regulation of cellular amine metabolic process GO:0033240 0 0.010
cellular protein metabolic process GO:0044267 129 0.010
positive regulation of response to stimulus GO:0048584 80 0.010

ttc21b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.026
sensory system disease DOID:0050155 0 0.012
nervous system disease DOID:863 0 0.012