Danio rerio

0 known processes

pfkfb4l

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4, like

(Aliases: pfkfb4)

pfkfb4l biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of localization GO:0032879 104 0.106
positive regulation of catabolic process GO:0009896 4 0.092
rna biosynthetic process GO:0032774 181 0.086
multicellular organismal metabolic process GO:0044236 2 0.084
regulation of signal transduction GO:0009966 225 0.081
regulation of metal ion transport GO:0010959 4 0.077
gene expression GO:0010467 252 0.075
larval development GO:0002164 2 0.066
response to monosaccharide GO:0034284 3 0.063
cellular macromolecule biosynthetic process GO:0034645 224 0.063
modification dependent protein catabolic process GO:0019941 3 0.061
cellular component movement GO:0006928 335 0.058
regulation of circadian rhythm GO:0042752 4 0.054
phagocytosis GO:0006909 3 0.054
regulation of cell cycle GO:0051726 52 0.054
rna metabolic process GO:0016070 219 0.053
cellular nitrogen compound metabolic process GO:0034641 290 0.053
transport GO:0006810 220 0.052
female gonad development GO:0008585 4 0.051
morphogenesis of an epithelium GO:0002009 333 0.050
organic cyclic compound biosynthetic process GO:1901362 223 0.050
autophagy GO:0006914 4 0.049
multicellular organism growth GO:0035264 4 0.049
positive regulation of cellular catabolic process GO:0031331 3 0.046
regulation of response to stimulus GO:0048583 269 0.045
response to carbohydrate GO:0009743 3 0.045
modification dependent macromolecule catabolic process GO:0043632 3 0.045
response to external stimulus GO:0009605 264 0.043
regulation of nitrogen compound metabolic process GO:0051171 251 0.040
macromolecule biosynthetic process GO:0009059 227 0.040
regulation of multicellular organism growth GO:0040014 4 0.039
response to organic substance GO:0010033 153 0.038
positive regulation of cellular component biogenesis GO:0044089 3 0.038
locomotion GO:0040011 313 0.037
aging GO:0007568 2 0.037
cellular component morphogenesis GO:0032989 336 0.036
negative regulation of protein complex assembly GO:0031333 1 0.036
nucleobase containing compound biosynthetic process GO:0034654 205 0.036
regulation of protein binding GO:0043393 3 0.035
cellular response to decreased oxygen levels GO:0036294 1 0.035
regulation of primary metabolic process GO:0080090 311 0.035
adult behavior GO:0030534 2 0.035
ion transmembrane transport GO:0034220 91 0.034
neuronal stem cell maintenance GO:0097150 2 0.032
sensory organ development GO:0007423 393 0.032
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.032
collagen biosynthetic process GO:0032964 2 0.031
regulation of multicellular organismal metabolic process GO:0044246 2 0.031
protein modification process GO:0036211 100 0.031
compound eye development GO:0048749 2 0.031
system process GO:0003008 185 0.031
organic acid metabolic process GO:0006082 31 0.031
regulation of rna metabolic process GO:0051252 224 0.031
cellular response to nutrient levels GO:0031669 2 0.031
regulation of developmental process GO:0050793 247 0.031
embryo development ending in birth or egg hatching GO:0009792 271 0.030
single organism metabolic process GO:0044710 217 0.030
signal transduction GO:0007165 455 0.030
regulation of signaling GO:0023051 235 0.029
negative regulation of cellular process GO:0048523 283 0.029
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.029
organelle organization GO:0006996 227 0.029
cellular carbohydrate metabolic process GO:0044262 4 0.028
regulation of binding GO:0051098 3 0.028
neurological system process GO:0050877 62 0.028
positive regulation of biological process GO:0048518 253 0.028
cellular response to hypoxia GO:0071456 1 0.028
regulation of protein complex assembly GO:0043254 3 0.028
regulation of cell communication GO:0010646 232 0.027
protein import into nucleus GO:0006606 3 0.027
cellular response to starvation GO:0009267 1 0.027
single organism transport GO:0044765 206 0.027
response to chemical GO:0042221 320 0.027
positive regulation of signal transduction GO:0009967 56 0.027
single organism nuclear import GO:1902593 3 0.027
anion transport GO:0006820 38 0.026
positive regulation of apoptotic signaling pathway GO:2001235 1 0.026
positive regulation of protein polymerization GO:0032273 2 0.026
fatty acid transport GO:0015908 1 0.026
organic substance biosynthetic process GO:1901576 289 0.026
energy reserve metabolic process GO:0006112 2 0.026
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.026
cellular response to extracellular stimulus GO:0031668 2 0.025
positive regulation of transport GO:0051050 2 0.025
head development GO:0060322 303 0.025
regulation of cellular amine metabolic process GO:0033238 0 0.025
protein polyubiquitination GO:0000209 4 0.025
regulation of calcium ion transport GO:0051924 2 0.025
positive regulation of cell adhesion GO:0045785 1 0.025
carbohydrate derivative biosynthetic process GO:1901137 43 0.024
positive regulation of response to stimulus GO:0048584 80 0.024
cell morphogenesis GO:0000902 289 0.024
homeostasis of number of cells within a tissue GO:0048873 4 0.024
carboxylic acid metabolic process GO:0019752 22 0.024
cellular component disassembly GO:0022411 1 0.024
regulation of ion transport GO:0043269 22 0.023
response to abiotic stimulus GO:0009628 122 0.023
regulation of nucleic acid templated transcription GO:1903506 213 0.023
negative regulation of biological process GO:0048519 304 0.023
female sex differentiation GO:0046660 4 0.023
oxoacid metabolic process GO:0043436 31 0.023
regulation of cell growth GO:0001558 29 0.023
dicarboxylic acid transport GO:0006835 1 0.023
cellular amino acid metabolic process GO:0006520 7 0.022
positive regulation of cellular process GO:0048522 201 0.022
heterocycle biosynthetic process GO:0018130 215 0.022
regulation of oligodendrocyte differentiation GO:0048713 1 0.022
ovulation cycle process GO:0022602 2 0.022
single organism localization GO:1902578 225 0.022
regulation of dendrite development GO:0050773 3 0.022
cell substrate adhesion GO:0031589 4 0.022
apoptotic process GO:0006915 116 0.022
cell morphogenesis involved in differentiation GO:0000904 195 0.022
alpha amino acid metabolic process GO:1901605 3 0.022
estrogen metabolic process GO:0008210 2 0.021
organic cyclic compound metabolic process GO:1901360 301 0.021
organonitrogen compound metabolic process GO:1901564 74 0.021
regulation of cell shape GO:0008360 1 0.021
vasculature development GO:0001944 278 0.021
generation of neurons GO:0048699 385 0.021
nitrogen compound metabolic process GO:0006807 319 0.021
sleep GO:0030431 1 0.020
protein localization to nucleus GO:0034504 3 0.020
transcription dna templated GO:0006351 181 0.020
regulation of biosynthetic process GO:0009889 250 0.020
nucleobase containing compound metabolic process GO:0006139 274 0.020
nucleic acid templated transcription GO:0097659 181 0.020
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.020
response to hexose GO:0009746 3 0.019
localization of cell GO:0051674 244 0.019
small molecule metabolic process GO:0044281 77 0.019
regulation of cellular metabolic process GO:0031323 320 0.019
regulation of cellular component organization GO:0051128 86 0.019
positive regulation of nucleoside metabolic process GO:0045979 1 0.019
protein targeting to nucleus GO:0044744 3 0.019
regulation of muscle contraction GO:0006937 3 0.019
regulation of protein catabolic process GO:0042176 1 0.019
negative regulation of cytokine production GO:0001818 1 0.019
regulation of biological quality GO:0065008 263 0.019
establishment of protein localization to organelle GO:0072594 4 0.019
protein import GO:0017038 3 0.018
cell death GO:0008219 121 0.018
positive regulation of cell communication GO:0010647 56 0.018
single organism biosynthetic process GO:0044711 71 0.018
central nervous system development GO:0007417 387 0.018
macromolecule modification GO:0043412 111 0.018
meiotic nuclear division GO:0007126 4 0.018
maintenance of location GO:0051235 4 0.018
entrainment of circadian clock GO:0009649 2 0.017
embryonic organ morphogenesis GO:0048562 274 0.017
regulation of wound healing GO:0061041 2 0.017
camera type eye development GO:0043010 222 0.017
cell projection morphogenesis GO:0048858 244 0.017
regulation of carbohydrate metabolic process GO:0006109 4 0.017
development of primary female sexual characteristics GO:0046545 4 0.017
regulation of transport GO:0051049 45 0.017
nuclear transport GO:0051169 4 0.017
primary neural tube formation GO:0014020 1 0.017
response to alkaloid GO:0043279 2 0.017
cellular response to external stimulus GO:0071496 2 0.017
cell part morphogenesis GO:0032990 246 0.017
regulation of protein polymerization GO:0032271 2 0.017
negative regulation of kinase activity GO:0033673 4 0.016
programmed cell death GO:0012501 119 0.016
response to biotic stimulus GO:0009607 97 0.016
regulation of multicellular organismal process GO:0051239 277 0.016
multicellular organismal macromolecule metabolic process GO:0044259 2 0.016
steroid hormone secretion GO:0035929 1 0.016
regulation of receptor mediated endocytosis GO:0048259 4 0.016
cellular biosynthetic process GO:0044249 286 0.016
long chain fatty acid metabolic process GO:0001676 1 0.016
response to nutrient GO:0007584 3 0.016
regulation of microtubule cytoskeleton organization GO:0070507 3 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.016
guanosine containing compound metabolic process GO:1901068 4 0.015
nuclear import GO:0051170 3 0.015
rna transport GO:0050658 2 0.015
positive regulation of protein kinase b signaling GO:0051897 1 0.015
aromatic compound biosynthetic process GO:0019438 217 0.015
hormone secretion GO:0046879 2 0.015
cell projection organization GO:0030030 284 0.015
cellular response to oxygen levels GO:0071453 1 0.015
macromolecular complex disassembly GO:0032984 1 0.015
pyruvate metabolic process GO:0006090 1 0.015
positive regulation of nucleotide catabolic process GO:0030813 1 0.015
cellular protein catabolic process GO:0044257 4 0.015
negative regulation of secretion GO:0051048 2 0.015
cell surface receptor signaling pathway GO:0007166 325 0.015
eye development GO:0001654 277 0.015
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.015
ubiquitin dependent protein catabolic process GO:0006511 3 0.015
response to glucose GO:0009749 3 0.014
cell substrate junction assembly GO:0007044 2 0.014
hormone transport GO:0009914 2 0.014
regulation of striated muscle contraction GO:0006942 2 0.014
regulation of hormone secretion GO:0046883 2 0.014
regulation of collagen metabolic process GO:0010712 2 0.014
regulation of transcription dna templated GO:0006355 213 0.014
hypothalamus cell differentiation GO:0021979 4 0.014
regulation of cell differentiation GO:0045595 142 0.014
regulation of circadian sleep wake cycle GO:0042749 1 0.014
regulation of cytokine production GO:0001817 3 0.014
chordate embryonic development GO:0043009 271 0.014
cognition GO:0050890 1 0.014
nucleic acid metabolic process GO:0090304 244 0.014
nucleocytoplasmic transport GO:0006913 4 0.014
regulation of anatomical structure morphogenesis GO:0022603 130 0.014
phosphatidylinositol mediated signaling GO:0048015 2 0.014
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.014
regulation of lipid transport GO:0032368 4 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.014
embryonic skeletal system development GO:0048706 97 0.014
cellular macromolecule metabolic process GO:0044260 391 0.014
protein complex disassembly GO:0043241 1 0.014
negative regulation of ras protein signal transduction GO:0046580 1 0.013
regulation of ion transmembrane transporter activity GO:0032412 2 0.013
peptidyl serine modification GO:0018209 2 0.013
regulation of dendrite morphogenesis GO:0048814 3 0.013
carbohydrate biosynthetic process GO:0016051 1 0.013
establishment of vesicle localization GO:0051650 24 0.013
regulation of endocrine process GO:0044060 2 0.013
positive regulation of gtp catabolic process GO:0033126 1 0.013
circadian sleep wake cycle GO:0042745 2 0.013
regulation of cellular protein catabolic process GO:1903362 1 0.013
negative regulation of epithelial cell proliferation GO:0050680 1 0.013
mitochondrion organization GO:0007005 4 0.013
regulation of neural precursor cell proliferation GO:2000177 3 0.013
pigmentation GO:0043473 85 0.013
hematopoietic or lymphoid organ development GO:0048534 191 0.013
axon development GO:0061564 166 0.013
regulation of transporter activity GO:0032409 2 0.013
retina development in camera type eye GO:0060041 146 0.013
regulation of cellular component movement GO:0051270 55 0.013
regulation of filopodium assembly GO:0051489 2 0.013
cellular amine metabolic process GO:0044106 2 0.013
regulation of macromolecule metabolic process GO:0060255 317 0.013
regulation of meiotic cell cycle GO:0051445 1 0.013
extrinsic apoptotic signaling pathway GO:0097191 3 0.013
amine metabolic process GO:0009308 2 0.013
actin filament based movement GO:0030048 1 0.013
negative regulation of locomotion GO:0040013 18 0.013
protein metabolic process GO:0019538 183 0.012
cellular modified amino acid metabolic process GO:0006575 3 0.012
positive regulation of cytoskeleton organization GO:0051495 3 0.012
stem cell maintenance GO:0019827 4 0.012
regulation of transmembrane transporter activity GO:0022898 2 0.012
membrane invagination GO:0010324 1 0.012
establishment of localization GO:0051234 244 0.012
regulation of ph GO:0006885 3 0.012
gtp catabolic process GO:0006184 2 0.012
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.012
regulation of cellular ketone metabolic process GO:0010565 7 0.012
stem cell differentiation GO:0048863 117 0.012
dna templated transcription initiation GO:0006352 1 0.012
positive regulation of gtpase activity GO:0043547 1 0.012
sequestering of calcium ion GO:0051208 3 0.012
mrna transport GO:0051028 2 0.012
regulation of locomotion GO:0040012 55 0.012
immune system process GO:0002376 241 0.012
regulation of programmed cell death GO:0043067 101 0.012
positive regulation of cell death GO:0010942 29 0.012
stem cell proliferation GO:0072089 4 0.011
response to oxygen containing compound GO:1901700 55 0.011
regulation of gene expression GO:0010468 265 0.011
spindle assembly GO:0051225 2 0.011
nucleobase containing compound transport GO:0015931 2 0.011
microtubule organizing center organization GO:0031023 1 0.011
cellular aromatic compound metabolic process GO:0006725 295 0.011
sensory perception of pain GO:0019233 1 0.011
circadian sleep wake cycle sleep GO:0050802 1 0.011
circadian sleep wake cycle process GO:0022410 2 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.011
gland development GO:0048732 143 0.011
positive regulation of protein complex assembly GO:0031334 2 0.011
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.011
response to stress GO:0006950 263 0.011
multicellular organismal response to stress GO:0033555 2 0.011
cell migration GO:0016477 237 0.011
establishment of rna localization GO:0051236 3 0.011
amino acid transport GO:0006865 2 0.011
regulation of cell morphogenesis GO:0022604 42 0.011
determination of bilateral symmetry GO:0009855 204 0.011
maternal determination of anterior posterior axis embryo GO:0008358 4 0.011
pancreas development GO:0031016 84 0.011
central nervous system neuron differentiation GO:0021953 74 0.011
regulation of purine nucleotide catabolic process GO:0033121 2 0.011
sequestering of metal ion GO:0051238 3 0.011
blood vessel development GO:0001568 246 0.011
regulation of response to extracellular stimulus GO:0032104 1 0.011
startle response GO:0001964 4 0.011
negative regulation of protein kinase activity GO:0006469 4 0.011
regulation of stem cell differentiation GO:2000736 4 0.010
enzyme linked receptor protein signaling pathway GO:0007167 106 0.010
death GO:0016265 121 0.010
centrosome organization GO:0051297 1 0.010
cell matrix adhesion GO:0007160 4 0.010
peptidyl serine phosphorylation GO:0018105 1 0.010
negative regulation of sequestering of calcium ion GO:0051283 4 0.010
lipid metabolic process GO:0006629 52 0.010
regulation of autophagy GO:0010506 3 0.010
embryonic skeletal system morphogenesis GO:0048704 93 0.010
smooth muscle tissue development GO:0048745 1 0.010
regulation of cellular amino acid metabolic process GO:0006521 0 0.010
regulation of macromolecule biosynthetic process GO:0010556 225 0.010
intracellular signal transduction GO:0035556 85 0.010
detection of external stimulus GO:0009581 24 0.010

pfkfb4l disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of mental health DOID:150 0 0.012
disease of anatomical entity DOID:7 0 0.012
cardiovascular system disease DOID:1287 0 0.011
disease of metabolism DOID:0014667 0 0.011