Danio rerio

35 known processes

sbds

Shwachman-Bodian-Diamond syndrome

(Aliases: MGC56700,zgc:56700)

sbds biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of cellular process GO:0048523 283 0.146
single organism metabolic process GO:0044710 217 0.131
negative regulation of biological process GO:0048519 304 0.108
larval development GO:0002164 2 0.108
aging GO:0007568 2 0.087
Worm
hemopoiesis GO:0030097 183 0.068
response to stress GO:0006950 263 0.068
programmed cell death GO:0012501 119 0.062
positive regulation of biological process GO:0048518 253 0.062
organonitrogen compound metabolic process GO:1901564 74 0.060
immune system process GO:0002376 241 0.059
cellular response to external stimulus GO:0071496 2 0.059
regulation of cell communication GO:0010646 232 0.059
small molecule metabolic process GO:0044281 77 0.058
death GO:0016265 121 0.058
regulation of signal transduction GO:0009966 225 0.057
apoptotic process GO:0006915 116 0.056
regulation of developmental process GO:0050793 247 0.054
cellular protein catabolic process GO:0044257 4 0.053
maintenance of location GO:0051235 4 0.052
signal transduction GO:0007165 455 0.049
cell proliferation GO:0008283 80 0.049
Mouse
positive regulation of cellular catabolic process GO:0031331 3 0.046
digestive tract development GO:0048565 265 0.045
lipid storage GO:0019915 1 0.044
carboxylic acid metabolic process GO:0019752 22 0.044
cellular response to chemical stimulus GO:0070887 157 0.044
mitochondrion organization GO:0007005 4 0.042
cellular response to nutrient levels GO:0031669 2 0.042
embryo development ending in birth or egg hatching GO:0009792 271 0.042
Mouse
response to chemical GO:0042221 320 0.041
regulation of cell death GO:0010941 103 0.040
regulation of multicellular organism growth GO:0040014 4 0.039
regulation of apoptotic process GO:0042981 98 0.037
positive regulation of catabolic process GO:0009896 4 0.037
positive regulation of blood circulation GO:1903524 2 0.035
regulation of signaling GO:0023051 235 0.035
single organism organelle organization GO:1902589 199 0.035
cellular response to extracellular stimulus GO:0031668 2 0.035
positive regulation of transport GO:0051050 2 0.034
response to drug GO:0042493 3 0.033
regulation of metabolic process GO:0019222 359 0.032
regulation of reactive oxygen species metabolic process GO:2000377 2 0.032
cytokinesis GO:0000910 3 0.031
purine nucleoside monophosphate catabolic process GO:0009128 4 0.030
nucleoside monophosphate catabolic process GO:0009125 4 0.030
regulation of programmed cell death GO:0043067 101 0.030
cellular component movement GO:0006928 335 0.030
multicellular organism growth GO:0035264 4 0.030
nitrogen compound metabolic process GO:0006807 319 0.030
cellular response to stress GO:0033554 62 0.029
negative regulation of response to stimulus GO:0048585 104 0.029
negative regulation of cell death GO:0060548 60 0.029
positive regulation of map kinase activity GO:0043406 3 0.029
regulation of protein transport GO:0051223 3 0.028
positive regulation of cellular process GO:0048522 201 0.028
cellular protein metabolic process GO:0044267 129 0.028
cellular nitrogen compound biosynthetic process GO:0044271 218 0.028
regulation of protein complex assembly GO:0043254 3 0.028
neuron differentiation GO:0030182 353 0.028
negative regulation of signaling GO:0023057 96 0.028
cell death GO:0008219 121 0.027
autophagy GO:0006914 4 0.027
regulation of multicellular organismal process GO:0051239 277 0.027
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.027
regulation of biological quality GO:0065008 263 0.027
lipid catabolic process GO:0016042 4 0.027
cellular amine metabolic process GO:0044106 2 0.027
heterocycle metabolic process GO:0046483 290 0.026
hematopoietic or lymphoid organ development GO:0048534 191 0.026
regulation of cytokine production GO:0001817 3 0.026
organic acid metabolic process GO:0006082 31 0.026
morphogenesis of an epithelium GO:0002009 333 0.025
nucleobase containing compound metabolic process GO:0006139 274 0.025
regulation of cellular metabolic process GO:0031323 320 0.025
regulation of cellular ketone metabolic process GO:0010565 7 0.025
regulation of localization GO:0032879 104 0.025
regulation of nitrogen compound metabolic process GO:0051171 251 0.024
protein import GO:0017038 3 0.024
atp catabolic process GO:0006200 4 0.024
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.024
regulation of protein catabolic process GO:0042176 1 0.024
single organism nuclear import GO:1902593 3 0.024
centrosome organization GO:0051297 1 0.023
negative regulation of catabolic process GO:0009895 3 0.023
hepaticobiliary system development GO:0061008 98 0.023
cell morphogenesis GO:0000902 289 0.023
establishment of protein localization to organelle GO:0072594 4 0.023
organelle organization GO:0006996 227 0.023
guanosine containing compound metabolic process GO:1901068 4 0.023
negative regulation of signal transduction GO:0009968 94 0.023
oxoacid metabolic process GO:0043436 31 0.022
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.022
myeloid cell differentiation GO:0030099 86 0.022
generation of neurons GO:0048699 385 0.022
cellular response to starvation GO:0009267 1 0.022
negative regulation of protein transport GO:0051224 3 0.022
nuclear transport GO:0051169 4 0.022
chordate embryonic development GO:0043009 271 0.022
Mouse
negative regulation of programmed cell death GO:0043069 58 0.021
positive regulation of cell cycle GO:0045787 3 0.021
positive regulation of cellular metabolic process GO:0031325 94 0.021
regulation of response to stimulus GO:0048583 269 0.021
cellular nitrogen compound metabolic process GO:0034641 290 0.021
regulation of epithelial cell proliferation GO:0050678 3 0.020
positive regulation of cellular amine metabolic process GO:0033240 0 0.020
positive regulation of secretion GO:0051047 1 0.020
amine metabolic process GO:0009308 2 0.020
cellular component assembly GO:0022607 170 0.019
positive regulation of cellular component biogenesis GO:0044089 3 0.019
cell projection organization GO:0030030 284 0.019
developmental growth GO:0048589 166 0.019
Mouse
transport GO:0006810 220 0.019
locomotion GO:0040011 313 0.019
negative regulation of gene expression GO:0010629 65 0.019
anterior posterior pattern specification GO:0009952 152 0.018
guanosine containing compound catabolic process GO:1901069 2 0.018
lipid oxidation GO:0034440 1 0.018
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.018
regulation of hormone secretion GO:0046883 2 0.018
cellular macromolecule metabolic process GO:0044260 391 0.018
regulation of cell differentiation GO:0045595 142 0.018
regulation of protein ubiquitination GO:0031396 3 0.017
regulation of binding GO:0051098 3 0.017
regulation of nucleotide catabolic process GO:0030811 2 0.017
multi organism process GO:0051704 134 0.017
liver development GO:0001889 96 0.017
ion transport GO:0006811 114 0.017
positive regulation of multi organism process GO:0043902 3 0.017
cytoskeleton dependent cytokinesis GO:0061640 3 0.017
cellular response to topologically incorrect protein GO:0035967 2 0.017
oxidation reduction process GO:0055114 41 0.016
positive regulation of protein complex assembly GO:0031334 2 0.016
regulation of response to extracellular stimulus GO:0032104 1 0.016
cellular amino acid metabolic process GO:0006520 7 0.016
protein targeting to nucleus GO:0044744 3 0.016
cell motility GO:0048870 244 0.016
organic cyclic compound metabolic process GO:1901360 301 0.016
regulation of purine nucleotide catabolic process GO:0033121 2 0.016
single organism transport GO:0044765 206 0.016
microtubule organizing center organization GO:0031023 1 0.016
reactive oxygen species metabolic process GO:0072593 6 0.016
extrinsic apoptotic signaling pathway GO:0097191 3 0.016
regulation of cellular protein catabolic process GO:1903362 1 0.016
positive regulation of metabolic process GO:0009893 108 0.016
pancreas development GO:0031016 84 0.016
macroautophagy GO:0016236 1 0.016
brain development GO:0007420 293 0.015
central nervous system development GO:0007417 387 0.015
mitotic cytokinesis GO:0000281 3 0.015
protein metabolic process GO:0019538 183 0.015
membrane fusion GO:0061025 2 0.015
ribonucleoside monophosphate catabolic process GO:0009158 4 0.015
regulation of intracellular protein transport GO:0033157 3 0.015
meiotic cell cycle process GO:1903046 3 0.015
response to other organism GO:0051707 97 0.015
phosphorus metabolic process GO:0006793 109 0.015
cell migration GO:0016477 237 0.015
cellular component morphogenesis GO:0032989 336 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
regulation of cellular protein metabolic process GO:0032268 52 0.014
regulation of nucleoside metabolic process GO:0009118 2 0.014
embryonic organ development GO:0048568 381 0.014
phosphate containing compound metabolic process GO:0006796 108 0.014
erythrocyte differentiation GO:0030218 54 0.014
wound healing GO:0042060 90 0.014
regulation of protein metabolic process GO:0051246 56 0.014
blood vessel development GO:0001568 246 0.014
establishment of localization GO:0051234 244 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.014
negative regulation of protein phosphorylation GO:0001933 4 0.014
negative regulation of secretion by cell GO:1903531 2 0.014
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.014
regulation of calcium ion transport GO:0051924 2 0.014
endosomal transport GO:0016197 2 0.014
cell projection morphogenesis GO:0048858 244 0.014
cellular biosynthetic process GO:0044249 286 0.014
nucleocytoplasmic transport GO:0006913 4 0.014
compound eye development GO:0048749 2 0.014
negative regulation of cellular metabolic process GO:0031324 77 0.013
negative regulation of apoptotic process GO:0043066 55 0.013
single organism localization GO:1902578 225 0.013
developmental growth involved in morphogenesis GO:0060560 86 0.013
convergent extension GO:0060026 118 0.013
regulation of phosphate metabolic process GO:0019220 43 0.013
negative regulation of cell differentiation GO:0045596 46 0.013
positive regulation of cytokine production GO:0001819 2 0.013
regulation of protein targeting GO:1903533 2 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.013
small molecule catabolic process GO:0044282 3 0.013
skin development GO:0043588 54 0.013
regulation of multicellular organismal development GO:2000026 223 0.013
biosynthetic process GO:0009058 294 0.013
regulation of cellular amine metabolic process GO:0033238 0 0.013
positive regulation of nucleotide catabolic process GO:0030813 1 0.013
nuclear import GO:0051170 3 0.013
er nucleus signaling pathway GO:0006984 2 0.013
dicarboxylic acid metabolic process GO:0043648 1 0.013
positive regulation of nucleoside metabolic process GO:0045979 1 0.013
nucleic acid metabolic process GO:0090304 244 0.013
tube morphogenesis GO:0035239 349 0.013
protein localization to nucleus GO:0034504 3 0.013
regulation of autophagy GO:0010506 3 0.013
heart development GO:0007507 313 0.013
negative regulation of cell communication GO:0010648 96 0.012
organelle fission GO:0048285 23 0.012
embryonic organ morphogenesis GO:0048562 274 0.012
regulation of cellular component organization GO:0051128 86 0.012
viral process GO:0016032 1 0.012
regulation of protein import into nucleus GO:0042306 2 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.012
regulation of rna biosynthetic process GO:2001141 213 0.012
spermatid differentiation GO:0048515 2 0.012
cell part morphogenesis GO:0032990 246 0.012
gene expression GO:0010467 252 0.012
rna metabolic process GO:0016070 219 0.012
positive regulation of secretion by cell GO:1903532 1 0.012
single organism biosynthetic process GO:0044711 71 0.012
positive regulation of cellular protein metabolic process GO:0032270 22 0.012
exocytosis GO:0006887 1 0.012
stem cell proliferation GO:0072089 4 0.012
sensory perception of pain GO:0019233 1 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.011
growth GO:0040007 174 0.011
Mouse
regulation of tube size GO:0035150 2 0.011
regulation of reproductive process GO:2000241 4 0.011
negative regulation of epithelial cell proliferation GO:0050680 1 0.011
tyrosine phosphorylation of stat protein GO:0007260 1 0.011
gland development GO:0048732 143 0.011
cellular response to dna damage stimulus GO:0006974 24 0.011
vasculature development GO:0001944 278 0.011
fatty acid biosynthetic process GO:0006633 4 0.011
organonitrogen compound biosynthetic process GO:1901566 47 0.011
regulation of establishment of protein localization GO:0070201 4 0.011
endoplasmic reticulum unfolded protein response GO:0030968 2 0.011
positive regulation of molecular function GO:0044093 33 0.011
cellular ketone metabolic process GO:0042180 11 0.011
response to bacterium GO:0009617 58 0.011
positive regulation of response to stimulus GO:0048584 80 0.011
regulation of lipid transport GO:0032368 4 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.011
protein import into nucleus GO:0006606 3 0.010
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.010
heterocycle biosynthetic process GO:0018130 215 0.010
head development GO:0060322 303 0.010
positive regulation of stress activated mapk cascade GO:0032874 3 0.010
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.010
regeneration GO:0031099 91 0.010
regulation of cell activation GO:0050865 1 0.010
gtp catabolic process GO:0006184 2 0.010
homeostasis of number of cells GO:0048872 62 0.010
cellular response to lipopolysaccharide GO:0071222 3 0.010
neuron development GO:0048666 262 0.010
regulation of muscle hypertrophy GO:0014743 2 0.010
rna biosynthetic process GO:0032774 181 0.010
regulation of intracellular signal transduction GO:1902531 57 0.010
negative regulation of multi organism process GO:0043901 3 0.010
regulation of gtpase activity GO:0043087 2 0.010
transcription dna templated GO:0006351 181 0.010
response to hydrogen peroxide GO:0042542 3 0.010
regulation of phosphorus metabolic process GO:0051174 43 0.010
lipid metabolic process GO:0006629 52 0.010
protein phosphorylation GO:0006468 47 0.010
regulation of membrane potential GO:0042391 23 0.010
regulation of response to nutrient levels GO:0032107 1 0.010
regulation of response to oxidative stress GO:1902882 2 0.010

sbds disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.058
disease of anatomical entity DOID:7 0 0.056
inherited metabolic disorder DOID:655 0 0.041
nervous system disease DOID:863 0 0.022
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011