Danio rerio

0 known processes

brip1

BRCA1 interacting protein C-terminal helicase 1

(Aliases: si:ch211-158l18.1,fancj)

brip1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
dna catabolic process GO:0006308 1 0.199
g2 dna damage checkpoint GO:0031572 3 0.173
response to stress GO:0006950 263 0.163
cellular aromatic compound metabolic process GO:0006725 295 0.153
nucleic acid metabolic process GO:0090304 244 0.148
nucleobase containing compound metabolic process GO:0006139 274 0.125
dna biosynthetic process GO:0071897 3 0.123
development of primary female sexual characteristics GO:0046545 4 0.117
male meiosis GO:0007140 2 0.114
regulation of establishment of protein localization GO:0070201 4 0.113
cellular component morphogenesis GO:0032989 336 0.103
dna metabolic process GO:0006259 27 0.100
heterocycle biosynthetic process GO:0018130 215 0.099
regulation of rna metabolic process GO:0051252 224 0.094
heterocycle metabolic process GO:0046483 290 0.093
meiotic cell cycle process GO:1903046 3 0.092
aromatic compound biosynthetic process GO:0019438 217 0.087
spermatid development GO:0007286 2 0.086
regionalization GO:0003002 274 0.085
embryo development ending in birth or egg hatching GO:0009792 271 0.082
synapsis GO:0007129 1 0.081
organic cyclic compound metabolic process GO:1901360 301 0.080
organelle organization GO:0006996 227 0.073
specification of axis polarity GO:0065001 4 0.070
regulation of transcription dna templated GO:0006355 213 0.069
nucleobase containing compound biosynthetic process GO:0034654 205 0.068
meiotic nuclear division GO:0007126 4 0.068
microtubule cytoskeleton organization GO:0000226 33 0.063
female sex differentiation GO:0046660 4 0.063
sex determination GO:0007530 1 0.061
cellular nitrogen compound metabolic process GO:0034641 290 0.060
female gonad development GO:0008585 4 0.058
response to alkaloid GO:0043279 2 0.058
nuclear transport GO:0051169 4 0.057
protein import into nucleus GO:0006606 3 0.057
determination of left right symmetry GO:0007368 179 0.054
cell cycle GO:0007049 93 0.054
cell projection organization GO:0030030 284 0.054
cell cycle process GO:0022402 53 0.054
regulation of biological quality GO:0065008 263 0.052
cell substrate adhesion GO:0031589 4 0.052
blood vessel development GO:0001568 246 0.051
meiotic chromosome segregation GO:0045132 3 0.049
microtubule organizing center organization GO:0031023 1 0.048
cellular response to dna damage stimulus GO:0006974 24 0.048
spermatid differentiation GO:0048515 2 0.048
regulation of nucleic acid templated transcription GO:1903506 213 0.047
negative regulation of nuclear division GO:0051784 3 0.047
intra s dna damage checkpoint GO:0031573 1 0.046
sprouting angiogenesis GO:0002040 53 0.045
organic cyclic compound biosynthetic process GO:1901362 223 0.045
organic substance biosynthetic process GO:1901576 289 0.044
cellular component movement GO:0006928 335 0.044
stem cell maintenance GO:0019827 4 0.044
double strand break repair via homologous recombination GO:0000724 1 0.044
homeostatic process GO:0042592 142 0.043
somatic cell dna recombination GO:0016444 1 0.043
b cell activation GO:0042113 2 0.043
single organism organelle organization GO:1902589 199 0.043
response to abiotic stimulus GO:0009628 122 0.043
signal transduction GO:0007165 455 0.043
mitotic dna integrity checkpoint GO:0044774 4 0.042
single organism reproductive process GO:0044702 40 0.041
mitotic dna damage checkpoint GO:0044773 4 0.040
cell cycle g2 m phase transition GO:0044839 4 0.040
regulation of protein import into nucleus GO:0042306 2 0.039
positive regulation of cell cycle GO:0045787 3 0.038
microtubule based process GO:0007017 60 0.036
rna metabolic process GO:0016070 219 0.036
regulation of dna templated transcription in response to stress GO:0043620 0 0.035
nitrogen compound metabolic process GO:0006807 319 0.035
double strand break repair GO:0006302 3 0.035
nucleocytoplasmic transport GO:0006913 4 0.035
regulation of rna biosynthetic process GO:2001141 213 0.034
production of molecular mediator of immune response GO:0002440 2 0.033
establishment of protein localization to organelle GO:0072594 4 0.033
regulation of protein localization to nucleus GO:1900180 2 0.033
mitotic nuclear division GO:0007067 18 0.032
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.032
macromolecule biosynthetic process GO:0009059 227 0.031
digestive system development GO:0055123 289 0.031
cellular macromolecule metabolic process GO:0044260 391 0.031
b cell mediated immunity GO:0019724 3 0.031
regulation of nitrogen compound metabolic process GO:0051171 251 0.031
signal transduction by p53 class mediator GO:0072331 13 0.030
cellular response to stress GO:0033554 62 0.030
organelle fission GO:0048285 23 0.030
single organism metabolic process GO:0044710 217 0.030
locomotion GO:0040011 313 0.030
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.029
cellular response to external stimulus GO:0071496 2 0.029
response to uv GO:0009411 3 0.028
regulation of multicellular organism growth GO:0040014 4 0.028
cell projection assembly GO:0030031 64 0.027
regulation of protein catabolic process GO:0042176 1 0.027
negative regulation of mitosis GO:0045839 3 0.027
cilium organization GO:0044782 71 0.027
cell motility GO:0048870 244 0.027
positive regulation of dna metabolic process GO:0051054 1 0.027
cell morphogenesis GO:0000902 289 0.026
regulation of protein targeting GO:1903533 2 0.026
cell part morphogenesis GO:0032990 246 0.026
positive regulation of cellular component biogenesis GO:0044089 3 0.026
nuclear import GO:0051170 3 0.026
response to superoxide GO:0000303 2 0.026
regulation of microtubule cytoskeleton organization GO:0070507 3 0.025
multicellular organismal reproductive process GO:0048609 35 0.025
multicellular organism growth GO:0035264 4 0.025
taste bud formation GO:0061195 3 0.025
vacuolar transport GO:0007034 2 0.025
recombinational repair GO:0000725 1 0.025
regulation of protein transport GO:0051223 3 0.025
response to radiation GO:0009314 51 0.024
protein import GO:0017038 3 0.024
localization of cell GO:0051674 244 0.024
negative regulation of developmental process GO:0051093 65 0.024
multicellular organism reproduction GO:0032504 35 0.023
regulation of cell death GO:0010941 103 0.023
vasculature development GO:0001944 278 0.023
centrosome organization GO:0051297 1 0.023
protein targeting to nucleus GO:0044744 3 0.023
immunoglobulin mediated immune response GO:0016064 3 0.023
negative regulation of biological process GO:0048519 304 0.023
phosphorus metabolic process GO:0006793 109 0.022
immunoglobulin production GO:0002377 1 0.022
reproduction GO:0000003 40 0.022
protein localization to nucleus GO:0034504 3 0.022
transcription from rna polymerase ii promoter GO:0006366 80 0.022
cellular nitrogen compound biosynthetic process GO:0044271 218 0.022
organelle assembly GO:0070925 110 0.021
centrosome cycle GO:0007098 1 0.021
protein modification process GO:0036211 100 0.021
connective tissue development GO:0061448 99 0.021
regulation of intracellular protein transport GO:0033157 3 0.021
tube morphogenesis GO:0035239 349 0.021
cell projection morphogenesis GO:0048858 244 0.021
positive regulation of cellular process GO:0048522 201 0.020
cell migration GO:0016477 237 0.020
cellular amine metabolic process GO:0044106 2 0.020
reciprocal dna recombination GO:0035825 1 0.020
cellular protein modification process GO:0006464 100 0.020
positive regulation of biological process GO:0048518 253 0.020
ovulation cycle GO:0042698 2 0.020
cellular macromolecule biosynthetic process GO:0034645 224 0.020
establishment of localization GO:0051234 244 0.020
cilium morphogenesis GO:0060271 85 0.020
intracellular signal transduction GO:0035556 85 0.020
determination of bilateral symmetry GO:0009855 204 0.019
purine nucleoside monophosphate catabolic process GO:0009128 4 0.019
rna biosynthetic process GO:0032774 181 0.019
positive regulation of macromolecule metabolic process GO:0010604 93 0.019
maintenance of location GO:0051235 4 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.019
protein stabilization GO:0050821 2 0.019
transcription dna templated GO:0006351 181 0.019
chordate embryonic development GO:0043009 271 0.018
chromosome organization GO:0051276 31 0.018
mitotic g2 m transition checkpoint GO:0044818 3 0.018
programmed cell death GO:0012501 119 0.018
cellular component assembly involved in morphogenesis GO:0010927 107 0.018
g2 m transition of mitotic cell cycle GO:0000086 4 0.018
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.018
regulation of cellular biosynthetic process GO:0031326 245 0.018
regulation of cytoplasmic transport GO:1903649 4 0.018
regulation of dna metabolic process GO:0051052 11 0.017
regulation of meiotic cell cycle GO:0051445 1 0.017
peptidyl serine phosphorylation GO:0018105 1 0.017
single organism cellular localization GO:1902580 46 0.017
developmental process involved in reproduction GO:0003006 27 0.017
atp catabolic process GO:0006200 4 0.017
protein polymerization GO:0051258 4 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
death GO:0016265 121 0.016
cellular localization GO:0051641 97 0.016
protein localization GO:0008104 40 0.016
protein acylation GO:0043543 3 0.016
ribonucleoside monophosphate catabolic process GO:0009158 4 0.016
spindle assembly GO:0051225 2 0.016
reciprocal meiotic recombination GO:0007131 1 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.016
regulation of signaling GO:0023051 235 0.016
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.016
zymogen activation GO:0031638 3 0.016
histone h3 k4 methylation GO:0051568 2 0.016
cellular response to radiation GO:0071478 4 0.016
cytoskeleton organization GO:0007010 96 0.016
single organism transport GO:0044765 206 0.016
cellular biosynthetic process GO:0044249 286 0.016
cellular protein catabolic process GO:0044257 4 0.016
nucleoside monophosphate catabolic process GO:0009125 4 0.016
rna export from nucleus GO:0006405 1 0.016
stem cell differentiation GO:0048863 117 0.015
immune system process GO:0002376 241 0.015
biosynthetic process GO:0009058 294 0.015
single organism nuclear import GO:1902593 3 0.015
peptidyl serine modification GO:0018209 2 0.015
cellular component biogenesis GO:0044085 178 0.015
negative regulation of cytoplasmic transport GO:1903650 2 0.015
positive regulation of metabolic process GO:0009893 108 0.015
positive regulation of cellular biosynthetic process GO:0031328 68 0.015
adult behavior GO:0030534 2 0.015
gtp catabolic process GO:0006184 2 0.015
cell surface receptor signaling pathway GO:0007166 325 0.015
negative regulation of histone methylation GO:0031061 1 0.015
regulation of organelle assembly GO:1902115 4 0.014
dna templated transcription initiation GO:0006352 1 0.014
heart looping GO:0001947 94 0.014
positive regulation of cytoskeleton organization GO:0051495 3 0.014
apoptotic process GO:0006915 116 0.014
regulation of cell cycle process GO:0010564 20 0.014
mitotic recombination GO:0006312 2 0.014
positive regulation of gene expression GO:0010628 71 0.014
multi organism process GO:0051704 134 0.014
carboxylic acid metabolic process GO:0019752 22 0.014
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.014
regulation of localization GO:0032879 104 0.014
macromolecule localization GO:0033036 54 0.014
specification of symmetry GO:0009799 204 0.014
protein metabolic process GO:0019538 183 0.014
aging GO:0007568 2 0.014
cellular response to starvation GO:0009267 1 0.014
axis specification GO:0009798 43 0.014
chromosome organization involved in meiosis GO:0070192 1 0.014
regulation of nucleoside metabolic process GO:0009118 2 0.014
regulation of oocyte development GO:0060281 3 0.014
fertilization GO:0009566 3 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.013
regulation of stem cell proliferation GO:0072091 2 0.013
angiogenesis GO:0001525 158 0.013
regulation of histone h3 k9 methylation GO:0051570 2 0.013
positive regulation of catabolic process GO:0009896 4 0.013
modification dependent protein catabolic process GO:0019941 3 0.013
morphogenesis of an epithelium GO:0002009 333 0.013
catabolic process GO:0009056 32 0.013
cortical cytoskeleton organization GO:0030865 1 0.013
regulation of cellular amine metabolic process GO:0033238 0 0.013
cellular response to nutrient levels GO:0031669 2 0.013
negative chemotaxis GO:0050919 1 0.013
regulation of protein complex assembly GO:0043254 3 0.013
larval development GO:0002164 2 0.013
cell aging GO:0007569 2 0.013
positive regulation of cellular metabolic process GO:0031325 94 0.013
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.013
blood vessel morphogenesis GO:0048514 216 0.013
negative regulation of cellular catabolic process GO:0031330 3 0.013
peptidyl threonine phosphorylation GO:0018107 1 0.013
regulation of cysteine type endopeptidase activity GO:2000116 21 0.013
regulation of production of molecular mediator of immune response GO:0002700 1 0.013
amine metabolic process GO:0009308 2 0.013
regulation of nucleocytoplasmic transport GO:0046822 2 0.012
negative regulation of intracellular transport GO:0032387 3 0.012
cellular amino acid metabolic process GO:0006520 7 0.012
negative regulation of protein transport GO:0051224 3 0.012
mitotic cell cycle embryonic GO:0045448 2 0.012
ovulation cycle process GO:0022602 2 0.012
macromolecule modification GO:0043412 111 0.012
developmental growth GO:0048589 166 0.012
female meiotic division GO:0007143 2 0.012
phosphate containing compound metabolic process GO:0006796 108 0.011
skeletal muscle organ development GO:0060538 78 0.011
dna methylation on cytosine GO:0032776 3 0.011
retina morphogenesis in camera type eye GO:0060042 79 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.011
regulation of dna catabolic process GO:1903624 1 0.011
response to chemical GO:0042221 320 0.011
regulation of stem cell differentiation GO:2000736 4 0.011
digestive tract morphogenesis GO:0048546 231 0.011
protein phosphorylation GO:0006468 47 0.011
myeloid cell homeostasis GO:0002262 56 0.011
nucleobase containing compound catabolic process GO:0034655 15 0.011
sister chromatid cohesion GO:0007062 2 0.011
cellular protein metabolic process GO:0044267 129 0.011
regulation of mesenchymal cell proliferation GO:0010464 1 0.011
protein polyubiquitination GO:0000209 4 0.011
response to external stimulus GO:0009605 264 0.011
negative regulation of cellular process GO:0048523 283 0.011
germ line stem cell division GO:0042078 1 0.011
regulation of metabolic process GO:0019222 359 0.011
regulation of purine nucleotide catabolic process GO:0033121 2 0.011
hatching GO:0035188 4 0.011
inner ear receptor cell fate commitment GO:0060120 4 0.011
positive regulation of stem cell proliferation GO:2000648 1 0.011
exocrine pancreas development GO:0031017 28 0.010
negative regulation of metabolic process GO:0009892 86 0.010
central nervous system development GO:0007417 387 0.010
developmental programmed cell death GO:0010623 4 0.010
protein acetylation GO:0006473 2 0.010
maternal determination of anterior posterior axis embryo GO:0008358 4 0.010
regulation of response to stimulus GO:0048583 269 0.010
cellular response to oxygen radical GO:0071450 2 0.010
sister chromatid segregation GO:0000819 6 0.010
regulation of cellular metabolic process GO:0031323 320 0.010
mitotic g2 dna damage checkpoint GO:0007095 3 0.010
ovarian follicle development GO:0001541 2 0.010
endosomal transport GO:0016197 2 0.010
regulation of reactive oxygen species metabolic process GO:2000377 2 0.010

brip1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.693
disease of anatomical entity DOID:7 0 0.693
bone marrow disease DOID:4961 0 0.693
hematopoietic system disease DOID:74 0 0.693
congenital hypoplastic anemia DOID:1342 0 0.368
aplastic anemia DOID:12449 0 0.368
fanconi s anemia DOID:13636 0 0.368
anemia DOID:2355 0 0.368
cancer DOID:162 0 0.038
disease of cellular proliferation DOID:14566 0 0.038
organ system cancer DOID:0050686 0 0.030
nervous system disease DOID:863 0 0.014
thoracic cancer DOID:5093 0 0.012