Danio rerio

0 known processes

seh1l

SEH1-like (S. cerevisiae)

(Aliases: fa02g03,zgc:55977,wu:fa02g03)

seh1l biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular macromolecule metabolic process GO:0044260 391 0.346
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.319
gene expression GO:0010467 252 0.308
larval development GO:0002164 2 0.258
nitrogen compound metabolic process GO:0006807 319 0.226
response to stress GO:0006950 263 0.142
Mouse
regulation of biological quality GO:0065008 263 0.141
Human
nucleic acid metabolic process GO:0090304 244 0.138
regulation of macromolecule metabolic process GO:0060255 317 0.136
aging GO:0007568 2 0.136
regulation of metabolic process GO:0019222 359 0.129
organic cyclic compound metabolic process GO:1901360 301 0.125
protein metabolic process GO:0019538 183 0.121
regulation of gene expression GO:0010468 265 0.116
nucleobase containing compound metabolic process GO:0006139 274 0.111
cellular macromolecule biosynthetic process GO:0034645 224 0.107
regulation of primary metabolic process GO:0080090 311 0.102
stem cell maintenance GO:0019827 4 0.101
atp catabolic process GO:0006200 4 0.095
regulation of response to stimulus GO:0048583 269 0.091
locomotion GO:0040011 313 0.091
regulation of nitrogen compound metabolic process GO:0051171 251 0.089
rna biosynthetic process GO:0032774 181 0.089
heterocycle metabolic process GO:0046483 290 0.087
multicellular organism growth GO:0035264 4 0.084
biosynthetic process GO:0009058 294 0.083
regulation of establishment of protein localization GO:0070201 4 0.077
positive regulation of translation GO:0045727 1 0.077
organic substance biosynthetic process GO:1901576 289 0.076
rna metabolic process GO:0016070 219 0.075
nucleobase containing compound biosynthetic process GO:0034654 205 0.075
cellular aromatic compound metabolic process GO:0006725 295 0.074
rna localization GO:0006403 4 0.073
negative regulation of cellular process GO:0048523 283 0.069
purine nucleoside monophosphate catabolic process GO:0009128 4 0.068
ribonucleoside monophosphate catabolic process GO:0009158 4 0.067
negative regulation of developmental process GO:0051093 65 0.066
negative regulation of biological process GO:0048519 304 0.065
positive regulation of biological process GO:0048518 253 0.064
nucleoside monophosphate catabolic process GO:0009125 4 0.064
small molecule metabolic process GO:0044281 77 0.063
macromolecule biosynthetic process GO:0009059 227 0.063
cell surface receptor signaling pathway GO:0007166 325 0.062
regulation of developmental process GO:0050793 247 0.059
regulation of cellular metabolic process GO:0031323 320 0.054
aromatic compound biosynthetic process GO:0019438 217 0.054
cellular component biogenesis GO:0044085 178 0.053
macromolecule localization GO:0033036 54 0.053
Human
growth GO:0040007 174 0.052
positive regulation of transport GO:0051050 2 0.052
cellular nitrogen compound biosynthetic process GO:0044271 218 0.051
cellular nitrogen compound metabolic process GO:0034641 290 0.051
regulation of transcription dna templated GO:0006355 213 0.051
cell projection organization GO:0030030 284 0.050
cellular component assembly GO:0022607 170 0.048
organelle organization GO:0006996 227 0.048
Human Worm
regulation of biosynthetic process GO:0009889 250 0.045
alternative mrna splicing via spliceosome GO:0000380 1 0.045
regulation of protein transport GO:0051223 3 0.045
cellular biosynthetic process GO:0044249 286 0.045
regulation of cellular biosynthetic process GO:0031326 245 0.044
response to chemical GO:0042221 320 0.044
vasculature development GO:0001944 278 0.043
embryo development ending in birth or egg hatching GO:0009792 271 0.043
development of primary female sexual characteristics GO:0046545 4 0.042
regulation of cellular component organization GO:0051128 86 0.041
positive regulation of cell cycle GO:0045787 3 0.040
positive regulation of cellular process GO:0048522 201 0.039
negative regulation of metabolic process GO:0009892 86 0.039
axis specification GO:0009798 43 0.037
signal transduction GO:0007165 455 0.036
modification dependent macromolecule catabolic process GO:0043632 3 0.036
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.036
regulation of rna metabolic process GO:0051252 224 0.036
regulation of protein catabolic process GO:0042176 1 0.036
regulation of macromolecule biosynthetic process GO:0010556 225 0.036
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000462 1 0.032
positive regulation of cell adhesion GO:0045785 1 0.031
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.030
regulation of protein localization to nucleus GO:1900180 2 0.029
negative regulation of response to stimulus GO:0048585 104 0.029
regulation of protein ubiquitination GO:0031396 3 0.028
regulation of cellular protein metabolic process GO:0032268 52 0.028
regulation of reproductive process GO:2000241 4 0.028
negative regulation of axon regeneration GO:0048681 4 0.027
central nervous system development GO:0007417 387 0.027
system process GO:0003008 185 0.027
rna processing GO:0006396 25 0.026
negative regulation of neuron projection regeneration GO:0070571 4 0.026
positive regulation of secretion by cell GO:1903532 1 0.026
single organism metabolic process GO:0044710 217 0.026
negative regulation of macromolecule metabolic process GO:0010605 76 0.026
establishment of localization GO:0051234 244 0.026
Human
cellular component morphogenesis GO:0032989 336 0.026
organic acid metabolic process GO:0006082 31 0.025
positive regulation of secretion GO:0051047 1 0.025
regeneration GO:0031099 91 0.025
organic substance transport GO:0071702 58 0.025
generation of neurons GO:0048699 385 0.025
regulation of protein metabolic process GO:0051246 56 0.024
response to uv GO:0009411 3 0.024
transcription dna templated GO:0006351 181 0.024
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.024
response to wounding GO:0009611 116 0.024
positive regulation of cellular metabolic process GO:0031325 94 0.024
regulation of protein complex assembly GO:0043254 3 0.024
cellular response to stress GO:0033554 62 0.024
double strand break repair GO:0006302 3 0.024
programmed cell death GO:0012501 119 0.024
response to abiotic stimulus GO:0009628 122 0.024
nucleic acid templated transcription GO:0097659 181 0.024
cellular component disassembly GO:0022411 1 0.024
regulation of cell communication GO:0010646 232 0.023
regulation of signal transduction GO:0009966 225 0.023
head development GO:0060322 303 0.023
posttranscriptional regulation of gene expression GO:0010608 14 0.023
regulation of rna biosynthetic process GO:2001141 213 0.023
regulation of multicellular organism growth GO:0040014 4 0.023
neurological system process GO:0050877 62 0.023
fertilization GO:0009566 3 0.023
neuron projection development GO:0031175 180 0.023
negative regulation of cell projection organization GO:0031345 9 0.023
regulation of signaling GO:0023051 235 0.022
regulation of cell development GO:0060284 100 0.022
3 utr mediated mrna stabilization GO:0070935 3 0.022
establishment of rna localization GO:0051236 3 0.022
regulation of multicellular organismal process GO:0051239 277 0.022
segmentation GO:0035282 97 0.021
death GO:0016265 121 0.021
adherens junction organization GO:0034332 4 0.021
rna transport GO:0050658 2 0.021
transport GO:0006810 220 0.021
brain development GO:0007420 293 0.021
response to drug GO:0042493 3 0.020
single organism localization GO:1902578 225 0.020
Human
regulation of mrna processing GO:0050684 3 0.020
nucleic acid transport GO:0050657 2 0.020
rna stabilization GO:0043489 4 0.019
regulation of nervous system development GO:0051960 90 0.019
cell migration GO:0016477 237 0.019
cell part morphogenesis GO:0032990 246 0.019
negative regulation of cell differentiation GO:0045596 46 0.019
mrna metabolic process GO:0016071 20 0.019
nuclear export GO:0051168 1 0.019
regionalization GO:0003002 274 0.019
regulation of exocytosis GO:0017157 1 0.019
regulation of nucleic acid templated transcription GO:1903506 213 0.019
regulation of stem cell differentiation GO:2000736 4 0.019
regulation of cytoplasmic transport GO:1903649 4 0.019
blood vessel development GO:0001568 246 0.019
dna metabolic process GO:0006259 27 0.018
cell motility GO:0048870 244 0.018
multi organism process GO:0051704 134 0.018
Mouse Fly
single organism organelle organization GO:1902589 199 0.018
Human
negative regulation of protein processing GO:0010955 10 0.018
regulation of intracellular protein transport GO:0033157 3 0.018
cellular protein metabolic process GO:0044267 129 0.018
regulation of circadian rhythm GO:0042752 4 0.018
cellular amine metabolic process GO:0044106 2 0.018
protein modification process GO:0036211 100 0.018
cortical cytoskeleton organization GO:0030865 1 0.017
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.017
negative regulation of gene expression GO:0010629 65 0.017
regulation of neurogenesis GO:0050767 87 0.017
embryonic digestive tract morphogenesis GO:0048557 3 0.017
negative regulation of signaling GO:0023057 96 0.017
mitotic cell cycle phase transition GO:0044772 9 0.017
nucleobase containing compound transport GO:0015931 2 0.017
nucleobase containing small molecule metabolic process GO:0055086 32 0.016
pole plasm assembly GO:0007315 4 0.016
organic cyclic compound biosynthetic process GO:1901362 223 0.016
regulation of binding GO:0051098 3 0.016
mrna export from nucleus GO:0006406 1 0.016
regulation of cell activation GO:0050865 1 0.016
maternal determination of anterior posterior axis embryo GO:0008358 4 0.016
organophosphate metabolic process GO:0019637 37 0.016
mrna processing GO:0006397 14 0.016
macromolecular complex disassembly GO:0032984 1 0.016
cell junction organization GO:0034330 11 0.016
cellular protein catabolic process GO:0044257 4 0.015
protein localization to nucleus GO:0034504 3 0.015
synaptic growth at neuromuscular junction GO:0051124 2 0.015
gtp metabolic process GO:0046039 4 0.015
cytokinesis GO:0000910 3 0.015
embryonic organ development GO:0048568 381 0.015
regulation of cellular ketone metabolic process GO:0010565 7 0.015
carbohydrate derivative metabolic process GO:1901135 61 0.015
positive regulation of biosynthetic process GO:0009891 68 0.015
macromolecular complex assembly GO:0065003 35 0.015
regulation of cellular response to stress GO:0080135 20 0.014
enzyme linked receptor protein signaling pathway GO:0007167 106 0.014
neuron differentiation GO:0030182 353 0.014
positive regulation of apoptotic signaling pathway GO:2001235 1 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
cell aging GO:0007569 2 0.014
protein targeting to nucleus GO:0044744 3 0.014
cellular response to chemical stimulus GO:0070887 157 0.014
localization within membrane GO:0051668 1 0.014
response to external stimulus GO:0009605 264 0.014
Mouse
regulation of cell differentiation GO:0045595 142 0.014
intracellular mrna localization GO:0008298 1 0.014
regulation of synapse assembly GO:0051963 3 0.014
reproduction GO:0000003 40 0.014
Worm Fly
positive regulation of macromolecule metabolic process GO:0010604 93 0.014
positive regulation of cellular biosynthetic process GO:0031328 68 0.014
regulation of cellular amine metabolic process GO:0033238 0 0.014
macromolecule deacylation GO:0098732 3 0.014
cellular amino acid metabolic process GO:0006520 7 0.014
nuclear transport GO:0051169 4 0.013
adherens junction assembly GO:0034333 1 0.013
protein k63 linked ubiquitination GO:0070534 2 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.013
regulation of dna templated transcription elongation GO:0032784 3 0.013
guanosine containing compound metabolic process GO:1901068 4 0.013
positive regulation of cellular component biogenesis GO:0044089 3 0.013
macromolecule modification GO:0043412 111 0.013
regulation of growth GO:0040008 42 0.013
organonitrogen compound metabolic process GO:1901564 74 0.013
regulation of protein polymerization GO:0032271 2 0.013
multicellular organismal signaling GO:0035637 22 0.013
cellular component movement GO:0006928 335 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
negative regulation of reproductive process GO:2000242 3 0.012
exocytosis GO:0006887 1 0.012
positive regulation of chromatin modification GO:1903310 1 0.012
regulation of anatomical structure morphogenesis GO:0022603 130 0.012
regulation of multicellular organismal development GO:2000026 223 0.012
regulation of carbohydrate metabolic process GO:0006109 4 0.012
regulation of tube size GO:0035150 2 0.012
negative regulation of rna metabolic process GO:0051253 48 0.012
localization of cell GO:0051674 244 0.012
single organism cell adhesion GO:0098602 29 0.012
positive regulation of cell activation GO:0050867 1 0.012
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.012
oocyte anterior posterior axis specification GO:0007314 4 0.012
single organism reproductive process GO:0044702 40 0.012
Fly
organonitrogen compound biosynthetic process GO:1901566 47 0.012
heart development GO:0007507 313 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
protein polymerization GO:0051258 4 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.012
g1 s transition of mitotic cell cycle GO:0000082 1 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.012
cell death GO:0008219 121 0.012
behavior GO:0007610 74 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.012
female sex differentiation GO:0046660 4 0.012
regulation of cell shape GO:0008360 1 0.012
g2 dna damage checkpoint GO:0031572 3 0.011
macromolecular complex subunit organization GO:0043933 74 0.011
Human
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.011
positive regulation of catabolic process GO:0009896 4 0.011
regulation of dna metabolic process GO:0051052 11 0.011
gtp catabolic process GO:0006184 2 0.011
protein complex disassembly GO:0043241 1 0.011
transcription from rna polymerase ii promoter GO:0006366 80 0.011
somitogenesis GO:0001756 87 0.011
purine nucleotide metabolic process GO:0006163 27 0.011
positive regulation of cytoskeleton organization GO:0051495 3 0.011
translation GO:0006412 5 0.011
protein deacylation GO:0035601 3 0.011
spermatid differentiation GO:0048515 2 0.011
sensory perception GO:0007600 39 0.011
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.011
regulation of carbohydrate biosynthetic process GO:0043255 1 0.011
oxoacid metabolic process GO:0043436 31 0.011
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.011
immune system development GO:0002520 191 0.011
microtubule based process GO:0007017 60 0.011
Human
g2 m transition of mitotic cell cycle GO:0000086 4 0.011
regulation of protein processing GO:0070613 10 0.011
hematopoietic or lymphoid organ development GO:0048534 191 0.011
mitotic dna integrity checkpoint GO:0044774 4 0.011
regulation of protein targeting GO:1903533 2 0.011
hemopoiesis GO:0030097 183 0.011
embryonic limb morphogenesis GO:0030326 2 0.011
positive regulation of dna metabolic process GO:0051054 1 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.010
regulation of cell growth GO:0001558 29 0.010
positive regulation of metabolic process GO:0009893 108 0.010
actin polymerization or depolymerization GO:0008154 2 0.010
negative regulation of neuron differentiation GO:0045665 10 0.010
cortical granule exocytosis GO:0060471 1 0.010
cellular ketone metabolic process GO:0042180 11 0.010
regulation of synapse organization GO:0050807 3 0.010
prevention of polyspermy GO:0060468 1 0.010
cell cycle g2 m phase transition GO:0044839 4 0.010
cell projection morphogenesis GO:0048858 244 0.010
positive regulation of multi organism process GO:0043902 3 0.010

seh1l disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.056
auditory system disease DOID:2742 0 0.030
nonsyndromic deafness DOID:0050563 0 0.030
sensory system disease DOID:0050155 0 0.030
nervous system disease DOID:863 0 0.030
myopathy DOID:423 0 0.019
muscular disease DOID:0080000 0 0.019
musculoskeletal system disease DOID:17 0 0.019
muscle tissue disease DOID:66 0 0.019
x linked disease DOID:0050735 0 0.015
neuromuscular disease DOID:440 0 0.012
charcot marie tooth disease DOID:10595 0 0.012
neuropathy DOID:870 0 0.012