Danio rerio

0 known processes

ephb3a

eph receptor B3a

(Aliases: wu:fc62d03,ephb3,zek3,fc62d03,rtk3,ek3)

ephb3a biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cell surface receptor signaling pathway GO:0007166 325 0.872
Human
central nervous system development GO:0007417 387 0.860
Zebrafish Mouse Fly
hindbrain development GO:0030902 91 0.852
Zebrafish
cellular biosynthetic process GO:0044249 286 0.841
biosynthetic process GO:0009058 294 0.817
camera type eye development GO:0043010 222 0.804
larval development GO:0002164 2 0.804
rna biosynthetic process GO:0032774 181 0.795
embryonic organ development GO:0048568 381 0.786
eye development GO:0001654 277 0.784
regulation of response to stimulus GO:0048583 269 0.768
Human Zebrafish
regulation of macromolecule metabolic process GO:0060255 317 0.751
signal transduction GO:0007165 455 0.702
Human Mouse
regulation of metabolic process GO:0019222 359 0.686
Human
aromatic compound biosynthetic process GO:0019438 217 0.666
regulation of collateral sprouting of intact axon in response to injury GO:0048683 2 0.625
Zebrafish
organic cyclic compound biosynthetic process GO:1901362 223 0.555
sensory organ morphogenesis GO:0090596 200 0.529
generation of neurons GO:0048699 385 0.518
Zebrafish Mouse Worm
cell proliferation in forebrain GO:0021846 3 0.509
regulation of signaling GO:0023051 235 0.484
Human
locomotion GO:0040011 313 0.466
Human Zebrafish Mouse Worm
retina development in camera type eye GO:0060041 146 0.455
head development GO:0060322 303 0.452
Zebrafish Mouse Fly
nucleic acid metabolic process GO:0090304 244 0.449
heterocycle biosynthetic process GO:0018130 215 0.445
specification of symmetry GO:0009799 204 0.436
negative regulation of biological process GO:0048519 304 0.433
Zebrafish Worm
embryonic organ morphogenesis GO:0048562 274 0.419
heterocycle metabolic process GO:0046483 290 0.406
Human
organic cyclic compound metabolic process GO:1901360 301 0.403
Human Fly
negative regulation of neuron projection regeneration GO:0070571 4 0.398
Zebrafish
cell migration GO:0016477 237 0.390
Human Zebrafish Mouse
blood vessel development GO:0001568 246 0.387
Zebrafish Mouse
epidermal cell differentiation GO:0009913 36 0.383
nucleobase containing compound metabolic process GO:0006139 274 0.380
Human
determination of left right symmetry GO:0007368 179 0.377
camera type eye morphogenesis GO:0048593 108 0.371
neuron differentiation GO:0030182 353 0.370
Zebrafish Mouse Worm
gene expression GO:0010467 252 0.361
mesoderm development GO:0007498 88 0.360
negative regulation of axon regeneration GO:0048681 4 0.358
Zebrafish
rhombomere boundary formation GO:0021654 10 0.351
Zebrafish
forebrain development GO:0030900 96 0.345
Zebrafish Mouse
peripheral nervous system neuron differentiation GO:0048934 28 0.337
extraocular skeletal muscle development GO:0002074 3 0.329
neuron projection development GO:0031175 180 0.326
Zebrafish Mouse Worm
sensory organ development GO:0007423 393 0.324
brain development GO:0007420 293 0.316
Zebrafish Mouse Fly
gastrulation GO:0007369 208 0.315
regulation of transcription dna templated GO:0006355 213 0.300
embryonic camera type eye development GO:0031076 29 0.299
positive regulation of biological process GO:0048518 253 0.299
Mouse
digestive tract development GO:0048565 265 0.297
Mouse
spinal cord radial glial cell differentiation GO:0021531 2 0.290
negative regulation of cellular process GO:0048523 283 0.289
Zebrafish
digestive system development GO:0055123 289 0.288
Mouse
brain morphogenesis GO:0048854 18 0.285
regulation of nitrogen compound metabolic process GO:0051171 251 0.283
Human
determination of bilateral symmetry GO:0009855 204 0.277
regulation of cellular biosynthetic process GO:0031326 245 0.266
regulation of cell differentiation GO:0045595 142 0.264
Zebrafish Mouse
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.263
blood vessel morphogenesis GO:0048514 216 0.259
Zebrafish Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.258
Human Fly
regulation of signal transduction GO:0009966 225 0.257
Human
regulation of cell communication GO:0010646 232 0.257
Human
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.248
regulation of primary metabolic process GO:0080090 311 0.245
Human
determination of heart left right asymmetry GO:0061371 117 0.244
regulation of cellular metabolic process GO:0031323 320 0.241
Human
epidermis development GO:0008544 48 0.232
diencephalon morphogenesis GO:0048852 5 0.225
ear morphogenesis GO:0042471 64 0.217
somite development GO:0061053 96 0.214
positive regulation of metabolic process GO:0009893 108 0.208
eye morphogenesis GO:0048592 144 0.208
digestive tract morphogenesis GO:0048546 231 0.199
Mouse
bmp signaling pathway GO:0030509 52 0.199
regulation of gene expression GO:0010468 265 0.192
regulation of inner ear receptor cell differentiation GO:2000980 1 0.191
cellular macromolecule biosynthetic process GO:0034645 224 0.185
embryonic camera type eye morphogenesis GO:0048596 19 0.180
tube morphogenesis GO:0035239 349 0.178
Mouse
negative regulation of cellular metabolic process GO:0031324 77 0.175
regulation of biological quality GO:0065008 263 0.174
Zebrafish Mouse
nitrogen compound metabolic process GO:0006807 319 0.173
Human
regulation of rna metabolic process GO:0051252 224 0.172
transcription from rna polymerase ii promoter GO:0006366 80 0.168
embryonic eye morphogenesis GO:0048048 30 0.161
regionalization GO:0003002 274 0.156
Zebrafish
skeletal muscle organ development GO:0060538 78 0.155
negative regulation of collateral sprouting GO:0048671 2 0.152
Zebrafish
muscle cell differentiation GO:0042692 139 0.152
negative regulation of rna metabolic process GO:0051253 48 0.150
embryonic heart tube morphogenesis GO:0003143 108 0.150
cell differentiation in spinal cord GO:0021515 40 0.147
radial glial cell differentiation GO:0060019 2 0.146
diencephalon development GO:0021536 58 0.144
muscle cell fate determination GO:0007521 1 0.143
death GO:0016265 121 0.141
embryonic heart tube development GO:0035050 133 0.139
sexual reproduction GO:0019953 36 0.138
Worm
cellular nitrogen compound biosynthetic process GO:0044271 218 0.138
negative regulation of gene expression GO:0010629 65 0.137
striated muscle cell differentiation GO:0051146 129 0.135
nucleobase containing compound biosynthetic process GO:0034654 205 0.133
neural retina development GO:0003407 49 0.132
response to wounding GO:0009611 116 0.132
Zebrafish
oocyte maturation GO:0001556 4 0.131
Worm
cell fate commitment GO:0045165 99 0.130
mechanoreceptor differentiation GO:0042490 37 0.130
forebrain anterior posterior pattern specification GO:0021797 3 0.128
regulation of macromolecule biosynthetic process GO:0010556 225 0.125
neuron development GO:0048666 262 0.125
Zebrafish Mouse Worm
negative regulation of collateral sprouting of intact axon in response to injury GO:0048685 2 0.124
Zebrafish
retinal pigment epithelium development GO:0003406 8 0.124
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.123
macromolecule biosynthetic process GO:0009059 227 0.121
organic substance biosynthetic process GO:1901576 289 0.120
embryonic skeletal system morphogenesis GO:0048704 93 0.120
negative regulation of macromolecule metabolic process GO:0010605 76 0.118
regulation of programmed cell death GO:0043067 101 0.115
forebrain regionalization GO:0021871 4 0.115
cellular macromolecule metabolic process GO:0044260 391 0.114
Human Worm
non canonical wnt signaling pathway involved in heart development GO:0061341 2 0.114
regulation of biosynthetic process GO:0009889 250 0.113
negative regulation of rna biosynthetic process GO:1902679 45 0.110
ameboidal type cell migration GO:0001667 143 0.109
endodermal cell fate determination GO:0007493 2 0.108
cell proliferation GO:0008283 80 0.105
regulation of stem cell proliferation GO:0072091 2 0.105
negative regulation of nucleic acid templated transcription GO:1903507 45 0.104
inner ear morphogenesis GO:0042472 63 0.101
regulation of gastrulation GO:0010470 24 0.101
peripheral nervous system neuron development GO:0048935 22 0.100
muscle structure development GO:0061061 196 0.099
dorsal ventral pattern formation GO:0009953 125 0.097
cell migration involved in gastrulation GO:0042074 79 0.096
regulation of multicellular organismal development GO:2000026 223 0.095
Zebrafish Mouse
forebrain generation of neurons GO:0021872 14 0.095
enzyme linked receptor protein signaling pathway GO:0007167 106 0.095
Human
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.094
forebrain cell migration GO:0021885 1 0.093
formation of primary germ layer GO:0001704 62 0.092
regulation of bmp signaling pathway involved in heart jogging GO:2000223 12 0.089
retinal ganglion cell axon guidance GO:0031290 35 0.089
Mouse
cellular protein modification process GO:0006464 100 0.088
Human Worm
localization of cell GO:0051674 244 0.087
Human Zebrafish Mouse
cell death GO:0008219 121 0.087
positive regulation of response to stimulus GO:0048584 80 0.084
inner ear development GO:0048839 126 0.084
renal system development GO:0072001 94 0.084
retina morphogenesis in camera type eye GO:0060042 79 0.084
forebrain neuron differentiation GO:0021879 14 0.083
morphogenesis of an epithelial sheet GO:0002011 49 0.082
regulation of multicellular organism growth GO:0040014 4 0.082
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.082
Human
negative chemotaxis GO:0050919 1 0.081
organelle organization GO:0006996 227 0.081
protein modification process GO:0036211 100 0.080
Human Worm
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.079
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.079
Worm
meiotic nuclear division GO:0007126 4 0.079
response to stress GO:0006950 263 0.078
Zebrafish Fly
compound eye development GO:0048749 2 0.078
macromolecule modification GO:0043412 111 0.076
Human Worm
regulation of multicellular organismal process GO:0051239 277 0.076
Zebrafish Mouse Worm
cellular nitrogen compound metabolic process GO:0034641 290 0.074
Human
retinal cell programmed cell death GO:0046666 2 0.073
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.073
metencephalon development GO:0022037 27 0.073
cell projection morphogenesis GO:0048858 244 0.072
Zebrafish Mouse Worm
mesodermal cell differentiation GO:0048333 21 0.072
optic placode formation GO:0001743 4 0.072
forebrain neuron development GO:0021884 7 0.072
programmed cell death GO:0012501 119 0.071
cell cell signaling GO:0007267 52 0.071
Mouse
positive regulation of cell fate commitment GO:0010455 1 0.071
phosphate containing compound metabolic process GO:0006796 108 0.070
Human Worm
epithelial tube morphogenesis GO:0060562 148 0.070
neuron projection morphogenesis GO:0048812 161 0.068
Zebrafish Mouse Worm
bmp signaling pathway involved in determination of left right symmetry GO:0003154 14 0.067
mesodermal cell fate specification GO:0007501 12 0.065
urogenital system development GO:0001655 97 0.064
Mouse
ectodermal placode development GO:0071696 37 0.064
apoptotic process GO:0006915 116 0.064
nucleic acid templated transcription GO:0097659 181 0.064
regulation of axon extension GO:0030516 24 0.063
Zebrafish
wound healing GO:0042060 90 0.063
positive regulation of rna metabolic process GO:0051254 59 0.062
vasculature development GO:0001944 278 0.062
Zebrafish Mouse
positive regulation of epithelial cell differentiation GO:0030858 2 0.061
chordate embryonic development GO:0043009 271 0.061
behavior GO:0007610 74 0.060
morphogenesis of an epithelium GO:0002009 333 0.060
Zebrafish Worm
mesoderm formation GO:0001707 43 0.060
angiogenesis GO:0001525 158 0.060
Mouse
endodermal cell differentiation GO:0035987 19 0.059
facial nucleus development GO:0021754 7 0.059
synaptic target recognition GO:0008039 1 0.059
convergent extension GO:0060026 118 0.059
Zebrafish
immune system process GO:0002376 241 0.058
Mouse Fly
somitogenesis GO:0001756 87 0.058
regulation of apoptotic process GO:0042981 98 0.057
positive regulation of signaling GO:0023056 56 0.057
rhombomere development GO:0021546 19 0.057
Zebrafish
multi organism process GO:0051704 134 0.057
Worm
rhombomere formation GO:0021594 12 0.056
Zebrafish
phagocytosis GO:0006909 3 0.056
protein metabolic process GO:0019538 183 0.054
Human Worm
establishment of localization GO:0051234 244 0.054
cell motility GO:0048870 244 0.054
Human Zebrafish Mouse
skeletal system development GO:0001501 181 0.053
response to chemical GO:0042221 320 0.053
Mouse Worm
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.053
axon development GO:0061564 166 0.052
Zebrafish Mouse Worm
rna metabolic process GO:0016070 219 0.052
regulation of rna biosynthetic process GO:2001141 213 0.052
negative regulation of metabolic process GO:0009892 86 0.052
organ formation GO:0048645 17 0.052
endoderm development GO:0007492 49 0.051
cellular component movement GO:0006928 335 0.051
Human Zebrafish Mouse Worm
single organism metabolic process GO:0044710 217 0.051
Human Fly
regulation of epithelial cell proliferation GO:0050678 3 0.051
facial nerve development GO:0021561 3 0.051
negative regulation of axon extension GO:0030517 7 0.050
Zebrafish
pancreas development GO:0031016 84 0.050
positive regulation of endothelial cell differentiation GO:0045603 2 0.050
kupffer s vesicle development GO:0070121 50 0.049
thalamus development GO:0021794 6 0.049
cellular protein metabolic process GO:0044267 129 0.049
Human Worm
central nervous system neuron differentiation GO:0021953 74 0.048
Mouse
neuroblast proliferation GO:0007405 2 0.048
regulation of cellular component organization GO:0051128 86 0.047
Zebrafish Mouse
photoreceptor cell fate commitment GO:0046552 1 0.047
cell projection organization GO:0030030 284 0.047
Zebrafish Mouse Worm
paraxial mesoderm development GO:0048339 8 0.047
cell proliferation in hindbrain GO:0021534 4 0.047
ear development GO:0043583 127 0.047
regulation of neuron projection regeneration GO:0070570 7 0.046
Zebrafish
collateral sprouting of intact axon in response to injury GO:0048673 2 0.046
Zebrafish
regulation of developmental process GO:0050793 247 0.046
Zebrafish Mouse
peripheral nervous system development GO:0007422 55 0.046
Fly
limb bud formation GO:0060174 2 0.045
angioblast cell migration involved in selective angioblast sprouting GO:0035475 4 0.045
Zebrafish
negative regulation of transcription dna templated GO:0045892 45 0.045
negative regulation of cellular biosynthetic process GO:0031327 55 0.045
neuromuscular process GO:0050905 7 0.045
positive regulation of cell cycle GO:0045787 3 0.044
embryo development ending in birth or egg hatching GO:0009792 271 0.044
Worm
positive regulation of cellular process GO:0048522 201 0.044
Mouse
ectodermal placode morphogenesis GO:0071697 32 0.044
glial cell differentiation GO:0010001 42 0.044
regulation of skeletal muscle tissue development GO:0048641 4 0.043
reproduction GO:0000003 40 0.043
Worm
heart looping GO:0001947 94 0.043
response to lipid GO:0033993 60 0.043
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.043
regulation of bmp signaling pathway GO:0030510 39 0.043
regulation of nervous system development GO:0051960 90 0.042
Zebrafish Mouse
mesenchymal cell proliferation GO:0010463 1 0.042
cellular protein catabolic process GO:0044257 4 0.041
negative regulation of gastrulation GO:2000542 11 0.041
nucleocytoplasmic transport GO:0006913 4 0.041
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.041
multi organism reproductive process GO:0044703 36 0.040
Worm
regulation of cell death GO:0010941 103 0.040
negative regulation of multicellular organismal process GO:0051241 69 0.040
Zebrafish Worm
glial cell migration GO:0008347 3 0.040
positive regulation of macromolecule metabolic process GO:0010604 93 0.040
oogenesis GO:0048477 14 0.040
Worm
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.040
startle response GO:0001964 4 0.040
positive regulation of catabolic process GO:0009896 4 0.040
positive regulation of map kinase activity GO:0043406 3 0.040
striated muscle tissue development GO:0014706 110 0.039
adult behavior GO:0030534 2 0.039
positive regulation of signal transduction GO:0009967 56 0.039
regulation of wnt signaling pathway GO:0030111 53 0.039
primary neural tube formation GO:0014020 1 0.039
embryonic camera type eye formation GO:0060900 10 0.039
ectodermal placode formation GO:0060788 26 0.038
mesoderm morphogenesis GO:0048332 51 0.038
tissue regeneration GO:0042246 74 0.038
epithelial cell differentiation GO:0030855 116 0.038
single organism cellular localization GO:1902580 46 0.037
striated muscle cell development GO:0055002 108 0.037
skin development GO:0043588 54 0.037
membrane invagination GO:0010324 1 0.036
positive regulation of gene expression GO:0010628 71 0.036
body morphogenesis GO:0010171 16 0.036
Worm
positive regulation of cellular metabolic process GO:0031325 94 0.035
neural nucleus development GO:0048857 15 0.035
skeletal system morphogenesis GO:0048705 102 0.034
positive regulation of jun kinase activity GO:0043507 2 0.034
positive regulation of stem cell proliferation GO:2000648 1 0.034
negative regulation of response to stimulus GO:0048585 104 0.034
Zebrafish
posterior lateral line system development GO:0048915 46 0.034
forebrain dorsal ventral pattern formation GO:0021798 1 0.034
heart development GO:0007507 313 0.033
negative regulation of endodermal cell differentiation GO:1903225 8 0.033
protein import into nucleus GO:0006606 3 0.032
cell cycle GO:0007049 93 0.032
regulation of endodermal cell differentiation GO:1903224 15 0.032
multicellular organism growth GO:0035264 4 0.032
positive regulation of transport GO:0051050 2 0.032
somatic stem cell maintenance GO:0035019 1 0.032
establishment of protein localization to organelle GO:0072594 4 0.031
regulation of jun kinase activity GO:0043506 3 0.031
motor neuron axon guidance GO:0008045 23 0.031
regulation of oocyte development GO:0060281 3 0.031
phosphorus metabolic process GO:0006793 109 0.031
Human Worm
protein localization to nucleus GO:0034504 3 0.031
neuroblast differentiation GO:0014016 1 0.031
cell recognition GO:0008037 19 0.030
Zebrafish Mouse
eye photoreceptor cell development GO:0042462 30 0.030
regulation of neurogenesis GO:0050767 87 0.030
Zebrafish Mouse
muscle fiber development GO:0048747 52 0.030
stem cell proliferation GO:0072089 4 0.030
response to external stimulus GO:0009605 264 0.030
Zebrafish Mouse Worm
developmental maturation GO:0021700 34 0.030
Worm
regulation of nucleic acid templated transcription GO:1903506 213 0.029
regulation of neural precursor cell proliferation GO:2000177 3 0.029
regulation of reproductive process GO:2000241 4 0.029
Worm
negative regulation of biosynthetic process GO:0009890 55 0.029
mesodermal cell migration GO:0008078 12 0.029
olfactory lobe development GO:0021988 4 0.029
negative regulation of axon guidance GO:1902668 1 0.029
regulation of synapse organization GO:0050807 3 0.029
Mouse
nerve development GO:0021675 45 0.028
transport GO:0006810 220 0.028
regulation of cell proliferation GO:0042127 37 0.028
pharyngeal muscle development GO:0043282 4 0.028
developmental growth involved in morphogenesis GO:0060560 86 0.028
Zebrafish
embryonic limb morphogenesis GO:0030326 2 0.028
muscle cell development GO:0055001 115 0.028
regulation of embryonic development GO:0045995 47 0.028
notch signaling pathway GO:0007219 35 0.027
germ cell development GO:0007281 22 0.027
Worm
single organism nuclear import GO:1902593 3 0.027
positive regulation of embryonic development GO:0040019 3 0.027
skeletal muscle fiber development GO:0048741 35 0.027
positive regulation of cell fate specification GO:0042660 1 0.027
wnt signaling pathway GO:0016055 80 0.027
appendage development GO:0048736 80 0.026
nephron epithelium morphogenesis GO:0072088 1 0.026
neural crest cell migration GO:0001755 42 0.026
regulation of cell cycle GO:0051726 52 0.026
phosphorylation GO:0016310 69 0.026
Human Worm
epithelium regeneration GO:1990399 14 0.026
regeneration GO:0031099 91 0.026
Zebrafish
neural precursor cell proliferation GO:0061351 20 0.025
axis specification GO:0009798 43 0.025
positive regulation of neural precursor cell proliferation GO:2000179 1 0.025
mesenchyme development GO:0060485 127 0.025
cell part morphogenesis GO:0032990 246 0.025
Zebrafish Mouse Worm
muscle tissue development GO:0060537 110 0.025
cellular component assembly GO:0022607 170 0.024
Mouse
neurological system process GO:0050877 62 0.024
cell morphogenesis involved in differentiation GO:0000904 195 0.024
Human Zebrafish Mouse Worm
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.024
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.024
Human
glial cell fate specification GO:0021780 4 0.023
optic placode formation involved in camera type eye formation GO:0046619 3 0.023
myotube differentiation GO:0014902 45 0.023
protein targeting to nucleus GO:0044744 3 0.023
fin development GO:0033333 77 0.023
transcription dna templated GO:0006351 181 0.023
g1 s transition of mitotic cell cycle GO:0000082 1 0.023
nuclear transport GO:0051169 4 0.023
regulation of mesenchymal cell proliferation GO:0010464 1 0.023
negative regulation of chromosome organization GO:2001251 1 0.022
renal tubule morphogenesis GO:0061333 1 0.022
single organism transport GO:0044765 206 0.022
heart contraction GO:0060047 71 0.022
negative regulation of neurogenesis GO:0050768 20 0.022
Zebrafish
kidney epithelium development GO:0072073 23 0.022
spinal cord motor neuron differentiation GO:0021522 26 0.022
endoderm formation GO:0001706 29 0.022
gliogenesis GO:0042063 45 0.022
face development GO:0060324 8 0.021
anterior posterior axon guidance GO:0033564 5 0.021
retina layer formation GO:0010842 24 0.021
regulation of synapse assembly GO:0051963 3 0.021
Mouse
negative regulation of signal transduction GO:0009968 94 0.021
regulation of cell development GO:0060284 100 0.021
Zebrafish Mouse
negative regulation of signaling GO:0023057 96 0.021
regulation of protein catabolic process GO:0042176 1 0.021
embryonic skeletal system development GO:0048706 97 0.020
mechanosensory lateral line system development GO:0048881 49 0.020
somatic muscle development GO:0007525 4 0.020
sex determination GO:0007530 1 0.020
foregut morphogenesis GO:0007440 4 0.020
regulation of locomotion GO:0040012 55 0.020
heart morphogenesis GO:0003007 156 0.019
regulation of catalytic activity GO:0050790 55 0.019
Human
regulation of canonical wnt signaling pathway GO:0060828 34 0.019
epiboly GO:0090504 41 0.019
response to alcohol GO:0097305 14 0.019
developmental process involved in reproduction GO:0003006 27 0.019
Worm
negative regulation of cell fate specification GO:0009996 11 0.019
bmp signaling pathway involved in heart jogging GO:0003303 14 0.019
gland development GO:0048732 143 0.019
Mouse
regulation of mechanoreceptor differentiation GO:0045631 1 0.019
erythrocyte homeostasis GO:0034101 55 0.019
oxoacid metabolic process GO:0043436 31 0.019
heart jogging GO:0003146 40 0.019
phagocytosis engulfment GO:0006911 1 0.018
neural tube development GO:0021915 62 0.018
negative regulation of endodermal cell fate specification GO:0042664 8 0.018
carbohydrate derivative metabolic process GO:1901135 61 0.018
Human
heart valve formation GO:0003188 4 0.018
negative regulation of developmental process GO:0051093 65 0.018
Zebrafish
single organism behavior GO:0044708 24 0.018
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.018
lateral line system development GO:0048925 76 0.018
protein import GO:0017038 3 0.018
reproductive process GO:0022414 40 0.018
Worm
forebrain morphogenesis GO:0048853 6 0.018
single organism organelle organization GO:1902589 199 0.018
vesicle mediated transport GO:0016192 22 0.018
developmental cell growth GO:0048588 52 0.017
Zebrafish
homeostatic process GO:0042592 142 0.017
positive regulation of skeletal muscle tissue development GO:0048643 1 0.017
macromolecular complex subunit organization GO:0043933 74 0.017
bone development GO:0060348 14 0.017
posterior lateral line development GO:0048916 38 0.017
morphogenesis of an epithelial fold GO:0060571 1 0.017
endocardial cell differentiation GO:0060956 5 0.017
olfactory bulb development GO:0021772 4 0.017
macromolecule localization GO:0033036 54 0.017
liver development GO:0001889 96 0.017
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.016
maintenance of location GO:0051235 4 0.016
protein phosphorylation GO:0006468 47 0.016
Human Worm
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.016
cardiac atrium development GO:0003230 4 0.016
kidney development GO:0001822 92 0.016
bmp signaling pathway involved in heart development GO:0061312 15 0.016
regulation of endodermal cell fate specification GO:0042663 15 0.016
protein localization GO:0008104 40 0.015
neural tube patterning GO:0021532 33 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.015
cell cell recognition GO:0009988 1 0.015
Zebrafish
oligodendrocyte differentiation GO:0048709 23 0.015
positive regulation of cellular biosynthetic process GO:0031328 68 0.015
cellular component morphogenesis GO:0032989 336 0.015
Human Zebrafish Mouse Worm
cellular component biogenesis GO:0044085 178 0.015
Mouse
regulation of neural retina development GO:0061074 2 0.015
neuromast hair cell differentiation GO:0048886 12 0.015
positive regulation of stress activated mapk cascade GO:0032874 3 0.014
negative regulation of embryonic development GO:0045992 11 0.014
endodermal cell fate commitment GO:0001711 18 0.014
stem cell maintenance GO:0019827 4 0.014
hindbrain formation GO:0021576 3 0.014
convergent extension involved in organogenesis GO:0060029 10 0.014
cell cycle g1 s phase transition GO:0044843 1 0.014
regulation of cytoplasmic transport GO:1903649 4 0.014
modification dependent macromolecule catabolic process GO:0043632 3 0.014
negative regulation of neuron differentiation GO:0045665 10 0.014
Zebrafish
cellular response to retinoic acid GO:0071300 1 0.014
cell morphogenesis GO:0000902 289 0.013
Human Zebrafish Mouse Worm
peripheral nervous system neuron axonogenesis GO:0048936 13 0.013
gamete generation GO:0007276 33 0.013
Worm
myotube cell development GO:0014904 35 0.013
neural crest cell development GO:0014032 62 0.013
nephron tubule epithelial cell differentiation GO:0072160 1 0.013
cardiac atrium morphogenesis GO:0003209 2 0.013
response to oxygen containing compound GO:1901700 55 0.013
negative regulation of apoptotic process GO:0043066 55 0.013
specification of organ position GO:0010159 3 0.013
regulation of anatomical structure morphogenesis GO:0022603 130 0.013
Zebrafish Mouse
organic hydroxy compound metabolic process GO:1901615 16 0.013
Fly
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 17 0.013
response to endogenous stimulus GO:0009719 83 0.013
fibroblast growth factor receptor signaling pathway GO:0008543 22 0.013
modification dependent protein catabolic process GO:0019941 3 0.013
synaptic growth at neuromuscular junction GO:0051124 2 0.013
mesodermal cell fate commitment GO:0001710 14 0.012
negative regulation of epithelial cell proliferation GO:0050680 1 0.012
lipid storage GO:0019915 1 0.012
muscle organ development GO:0007517 101 0.012
negative regulation of retinal cell programmed cell death GO:0046671 2 0.012
morphogenesis of embryonic epithelium GO:0016331 30 0.012
Worm
positive regulation of cell communication GO:0010647 56 0.012

ephb3a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
bone development disease DOID:0080006 0 0.020
bone disease DOID:0080001 0 0.020
disease of anatomical entity DOID:7 0 0.020
dysostosis DOID:1934 0 0.020
musculoskeletal system disease DOID:17 0 0.020
connective tissue disease DOID:65 0 0.020
nervous system disease DOID:863 0 0.014
epilepsy syndrome DOID:1826 0 0.014
central nervous system disease DOID:331 0 0.014
brain disease DOID:936 0 0.014
electroclinical syndrome DOID:0050701 0 0.014