Danio rerio

32 known processes

aqp1a.1

aquaporin 1a, tandem duplicate 1

(Aliases: fj33g04,zgc:85890,wu:fj33g04)

aqp1a.1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ammonium transmembrane transport GO:0072488 2 0.971
carbon dioxide transmembrane transport GO:0035378 1 0.943
urea transmembrane transport GO:0071918 9 0.903
Zebrafish
fluid transport GO:0042044 17 0.872
urea transport GO:0015840 11 0.827
Zebrafish
one carbon compound transport GO:0019755 14 0.732
aging GO:0007568 2 0.695
response to vitamin b3 GO:0033552 2 0.689
single organism localization GO:1902578 225 0.609
inorganic anion transport GO:0015698 25 0.519
water transport GO:0006833 15 0.488
chloride transport GO:0006821 8 0.384
cellular response to xenobiotic stimulus GO:0071466 35 0.333
response to nutrient GO:0007584 3 0.311
embryo development ending in birth or egg hatching GO:0009792 271 0.283
glycerol transport GO:0015793 7 0.253
response to vitamin GO:0033273 3 0.236
primitive erythrocyte differentiation GO:0060319 5 0.202
single organism transport GO:0044765 206 0.187
regulation of blood pressure GO:0008217 1 0.167
organic substance transport GO:0071702 58 0.153
response to chemical GO:0042221 320 0.153
gas transport GO:0015669 3 0.148
transport GO:0006810 220 0.135
signal transduction GO:0007165 455 0.133
regulation of cellular ph reduction GO:0032847 1 0.132
maintenance of location GO:0051235 4 0.132
positive regulation of cell adhesion GO:0045785 1 0.122
regulation of cell substrate adhesion GO:0010810 1 0.121
response to corticosteroid GO:0031960 1 0.119
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.118
renal absorption GO:0070293 1 0.111
Mouse
negative regulation of biological process GO:0048519 304 0.109
heart morphogenesis GO:0003007 156 0.108
lipid storage GO:0019915 1 0.101
sensory organ development GO:0007423 393 0.101
Zebrafish Mouse
heart development GO:0007507 313 0.094
response to steroid hormone GO:0048545 35 0.093
astrocyte differentiation GO:0048708 1 0.092
hematopoietic or lymphoid organ development GO:0048534 191 0.089
cell substrate adhesion GO:0031589 4 0.087
collagen metabolic process GO:0032963 2 0.082
ph reduction GO:0045851 1 0.081
response to drug GO:0042493 3 0.080
embryonic heart tube development GO:0035050 133 0.078
multicellular organismal macromolecule metabolic process GO:0044259 2 0.077
cellular response to chemical stimulus GO:0070887 157 0.074
regulation of localization GO:0032879 104 0.069
Mouse
multicellular organismal metabolic process GO:0044236 2 0.068
transmembrane transport GO:0055085 120 0.068
wound healing GO:0042060 90 0.066
Mouse
positive regulation of transport GO:0051050 2 0.065
rna metabolic process GO:0016070 219 0.065
nitrogen compound transport GO:0071705 23 0.064
g protein coupled receptor signaling pathway GO:0007186 74 0.064
metal ion transport GO:0030001 58 0.063
Mouse
primitive hemopoiesis GO:0060215 27 0.062
peptide transport GO:0015833 1 0.061
Mouse
renal system process GO:0003014 14 0.061
Mouse
cellular biosynthetic process GO:0044249 286 0.060
retinoic acid receptor signaling pathway GO:0048384 16 0.059
regulation of systemic arterial blood pressure GO:0003073 1 0.059
system process GO:0003008 185 0.059
Mouse
behavior GO:0007610 74 0.058
response to glucocorticoid GO:0051384 1 0.057
anion transmembrane transport GO:0098656 12 0.056
regulation of metal ion transport GO:0010959 4 0.055
protein complex assembly GO:0006461 30 0.054
oligopeptide transport GO:0006857 1 0.054
negative regulation of cellular process GO:0048523 283 0.054
immune system process GO:0002376 241 0.054
response to retinoic acid GO:0032526 6 0.054
cellular response to extracellular stimulus GO:0031668 2 0.053
camera type eye development GO:0043010 222 0.052
Zebrafish Mouse
anion transport GO:0006820 38 0.052
intestinal absorption GO:0050892 2 0.052
regeneration GO:0031099 91 0.051
ion transmembrane transport GO:0034220 91 0.050
positive regulation of cell substrate adhesion GO:0010811 1 0.050
homeostatic process GO:0042592 142 0.049
Mouse
negative regulation of signal transduction GO:0009968 94 0.049
regulation of retinoic acid receptor signaling pathway GO:0048385 5 0.049
vasculature development GO:0001944 278 0.049
Mouse
morphogenesis of an epithelium GO:0002009 333 0.048
macromolecule biosynthetic process GO:0009059 227 0.048
larval development GO:0002164 2 0.048
multicellular organismal water homeostasis GO:0050891 1 0.048
Mouse
cellular response to external stimulus GO:0071496 2 0.047
brain development GO:0007420 293 0.047
Mouse
organonitrogen compound metabolic process GO:1901564 74 0.047
monovalent inorganic cation transport GO:0015672 42 0.046
embryonic heart tube morphogenesis GO:0003143 108 0.044
cellular biogenic amine metabolic process GO:0006576 2 0.043
regulation of cell communication GO:0010646 232 0.043
ion transport GO:0006811 114 0.042
positive regulation of biological process GO:0048518 253 0.041
Mouse
organic cyclic compound metabolic process GO:1901360 301 0.041
protein heterooligomerization GO:0051291 1 0.039
response to fatty acid GO:0070542 5 0.039
carboxylic acid metabolic process GO:0019752 22 0.037
embryonic organ morphogenesis GO:0048562 274 0.037
cation transmembrane transport GO:0098655 65 0.037
positive regulation of cellular process GO:0048522 201 0.036
Mouse
regulation of biological quality GO:0065008 263 0.036
Mouse
positive regulation of transcription dna templated GO:0045893 57 0.036
eye development GO:0001654 277 0.036
Zebrafish Mouse
osteoclast development GO:0036035 1 0.036
lipid homeostasis GO:0055088 3 0.036
dipeptide transport GO:0042938 1 0.036
smooth muscle contraction GO:0006939 2 0.035
chordate embryonic development GO:0043009 271 0.035
small molecule metabolic process GO:0044281 77 0.035
cellular component assembly GO:0022607 170 0.035
establishment of localization GO:0051234 244 0.034
regulation of signaling GO:0023051 235 0.034
regulation of metabolic process GO:0019222 359 0.034
lens development in camera type eye GO:0002088 22 0.034
Zebrafish
nucleic acid templated transcription GO:0097659 181 0.033
cation transport GO:0006812 81 0.033
response to lipid GO:0033993 60 0.033
organic substance biosynthetic process GO:1901576 289 0.032
cellular macromolecule biosynthetic process GO:0034645 224 0.032
myeloid cell homeostasis GO:0002262 56 0.032
response to hormone GO:0009725 48 0.032
hypotonic response GO:0006971 5 0.031
organic anion transport GO:0015711 15 0.031
erythrocyte differentiation GO:0030218 54 0.030
response to external stimulus GO:0009605 264 0.030
macromolecular complex subunit organization GO:0043933 74 0.030
regulation of biosynthetic process GO:0009889 250 0.030
negative regulation of metabolic process GO:0009892 86 0.030
response to stress GO:0006950 263 0.030
Mouse
stem cell proliferation GO:0072089 4 0.030
hepaticobiliary system development GO:0061008 98 0.030
embryonic organ development GO:0048568 381 0.029
locomotion GO:0040011 313 0.029
Mouse
regulation of signal transduction GO:0009966 225 0.029
regulation of ectodermal cell fate specification GO:0042665 2 0.029
myeloid cell development GO:0061515 32 0.029
response to prostaglandin GO:0034694 5 0.029
neuron neuron synaptic transmission GO:0007270 1 0.028
ectodermal cell fate specification GO:0001715 2 0.028
striated muscle cell differentiation GO:0051146 129 0.028
localization of cell GO:0051674 244 0.028
Mouse
amine metabolic process GO:0009308 2 0.028
cell adhesion GO:0007155 40 0.028
circulatory system process GO:0003013 87 0.028
regulation of cell motility GO:2000145 46 0.027
Mouse
tube morphogenesis GO:0035239 349 0.027
response to xenobiotic stimulus GO:0009410 45 0.027
endothelium development GO:0003158 25 0.027
nucleic acid metabolic process GO:0090304 244 0.026
hemopoiesis GO:0030097 183 0.026
cell morphogenesis GO:0000902 289 0.026
striated muscle cell development GO:0055002 108 0.026
intestinal cholesterol absorption GO:0030299 2 0.026
organic acid metabolic process GO:0006082 31 0.026
growth GO:0040007 174 0.025
hindbrain morphogenesis GO:0021575 22 0.025
positive regulation of catabolic process GO:0009896 4 0.025
liver development GO:0001889 96 0.025
cellular component biogenesis GO:0044085 178 0.025
heart looping GO:0001947 94 0.024
skeletal muscle organ development GO:0060538 78 0.024
collagen biosynthetic process GO:0032964 2 0.024
negative regulation of macromolecule metabolic process GO:0010605 76 0.024
oxoacid metabolic process GO:0043436 31 0.023
fin regeneration GO:0031101 51 0.023
response to wounding GO:0009611 116 0.023
Mouse
sensory system development GO:0048880 76 0.023
bicarbonate transport GO:0015701 4 0.023
cellular nitrogen compound biosynthetic process GO:0044271 218 0.023
positive regulation of cell activation GO:0050867 1 0.022
rna biosynthetic process GO:0032774 181 0.022
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.022
skeletal system morphogenesis GO:0048705 102 0.022
reactive oxygen species biosynthetic process GO:1903409 1 0.021
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.021
macromolecular complex assembly GO:0065003 35 0.021
organic hydroxy compound transport GO:0015850 14 0.021
tissue regeneration GO:0042246 74 0.021
regulation of primary metabolic process GO:0080090 311 0.021
positive regulation of gliogenesis GO:0014015 2 0.021
glial cell development GO:0021782 20 0.021
cellular macromolecule metabolic process GO:0044260 391 0.021
actin filament based process GO:0030029 64 0.021
regulation of ph GO:0006885 3 0.020
cellular amine metabolic process GO:0044106 2 0.020
regulation of establishment of protein localization GO:0070201 4 0.020
long chain fatty acid transport GO:0015909 1 0.020
heart contraction GO:0060047 71 0.020
regulation of cellular ph GO:0030641 1 0.020
regulation of transport GO:0051049 45 0.020
single organism metabolic process GO:0044710 217 0.020
lateral line development GO:0048882 66 0.020
regulation of blood vessel size GO:0050880 2 0.020
biomineral tissue development GO:0031214 13 0.020
immune response GO:0006955 28 0.019
cellular nitrogen compound metabolic process GO:0034641 290 0.019
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.019
glucose homeostasis GO:0042593 1 0.019
negative regulation of protein complex assembly GO:0031333 1 0.019
regulation of ectoderm development GO:2000383 2 0.019
urogenital system development GO:0001655 97 0.019
Mouse
regulation of body fluid levels GO:0050878 16 0.019
Mouse
cellular response to organic cyclic compound GO:0071407 38 0.019
carbohydrate transport GO:0008643 13 0.019
central nervous system development GO:0007417 387 0.019
Mouse
cell projection morphogenesis GO:0048858 244 0.019
regulation of inflammatory response GO:0050727 2 0.019
endodermal cell fate determination GO:0007493 2 0.019
polyol transport GO:0015791 7 0.018
blood circulation GO:0008015 87 0.018
gene expression GO:0010467 252 0.018
lymphatic endothelial cell differentiation GO:0060836 1 0.018
cellular amino acid metabolic process GO:0006520 7 0.017
epiboly GO:0090504 41 0.017
blood vessel development GO:0001568 246 0.017
Mouse
ammonia homeostasis GO:0097272 3 0.017
regulation of tube size GO:0035150 2 0.017
regulation of binding GO:0051098 3 0.017
protein metabolic process GO:0019538 183 0.017
phagocytosis GO:0006909 3 0.017
determination of left right symmetry GO:0007368 179 0.017
positive regulation of cell cycle GO:0045787 3 0.017
stem cell maintenance GO:0019827 4 0.017
nitrogen compound metabolic process GO:0006807 319 0.017
response to decreased oxygen levels GO:0036293 25 0.017
lipid digestion GO:0044241 3 0.017
Mouse
regulation of cellular metabolic process GO:0031323 320 0.016
cellular response to endogenous stimulus GO:0071495 68 0.016
cellular response to nutrient levels GO:0031669 2 0.016
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.016
single organism membrane organization GO:0044802 20 0.016
cellular response to organic substance GO:0071310 105 0.016
regulation of rna biosynthetic process GO:2001141 213 0.016
trabecula morphogenesis GO:0061383 2 0.016
hormone transport GO:0009914 2 0.016
Mouse
lipid localization GO:0010876 11 0.016
actin cytoskeleton organization GO:0030036 63 0.016
ovulation cycle process GO:0022602 2 0.016
positive regulation of cellular catabolic process GO:0031331 3 0.016
homeostasis of number of cells GO:0048872 62 0.015
membrane fusion GO:0061025 2 0.015
response to endogenous stimulus GO:0009719 83 0.015
cellular component morphogenesis GO:0032989 336 0.015
protein secretion GO:0009306 1 0.015
carbon dioxide transport GO:0015670 3 0.015
hindbrain development GO:0030902 91 0.015
endothelial cell development GO:0001885 12 0.015
mitochondrion organization GO:0007005 4 0.015
regulation of response to stimulus GO:0048583 269 0.015
epithelial cell differentiation GO:0030855 116 0.015
cell cell signaling GO:0007267 52 0.015
Mouse
defense response GO:0006952 47 0.015
intracellular receptor signaling pathway GO:0030522 30 0.015
cell surface receptor signaling pathway GO:0007166 325 0.015
nucleobase containing compound metabolic process GO:0006139 274 0.015
response to estrogen GO:0043627 27 0.015
heterocycle metabolic process GO:0046483 290 0.014
determination of heart left right asymmetry GO:0061371 117 0.014
regulation of collagen metabolic process GO:0010712 2 0.014
heterocycle biosynthetic process GO:0018130 215 0.014
digestive system development GO:0055123 289 0.014
regulation of transcription from rna polymerase ii promoter in response to oxidative stress GO:0043619 0 0.014
positive regulation of cell differentiation GO:0045597 30 0.014
negative regulation of mesodermal cell fate specification GO:0042662 3 0.014
negative regulation of cytokine production GO:0001818 1 0.014
negative regulation of protein phosphorylation GO:0001933 4 0.014
positive regulation of cell death GO:0010942 29 0.014
specification of symmetry GO:0009799 204 0.014
cell death in response to oxidative stress GO:0036473 2 0.014
response to acid chemical GO:0001101 17 0.013
lymphocyte proliferation GO:0046651 1 0.013
muscle cell development GO:0055001 115 0.013
hatching gland development GO:0048785 3 0.013
regulation of cellular amine metabolic process GO:0033238 0 0.013
erythrocyte maturation GO:0043249 8 0.013
regulation of cytokine production GO:0001817 3 0.013
aromatic compound biosynthetic process GO:0019438 217 0.013
biological adhesion GO:0022610 40 0.013
erythrocyte homeostasis GO:0034101 55 0.013
inorganic cation transmembrane transport GO:0098662 50 0.013
positive regulation of immune effector process GO:0002699 3 0.013
inorganic anion transmembrane transport GO:0098661 10 0.013
regulation of sodium ion transport GO:0002028 2 0.013
regulation of hormone secretion GO:0046883 2 0.013
muscle structure development GO:0061061 196 0.013
response to glucose GO:0009749 3 0.012
response to extracellular stimulus GO:0009991 10 0.012
positive regulation of cell communication GO:0010647 56 0.012
response to organic cyclic compound GO:0014070 51 0.012
lymphoid lineage cell migration into thymus GO:0097535 4 0.012
organic cyclic compound biosynthetic process GO:1901362 223 0.012
negative regulation of secretion by cell GO:1903531 2 0.012
positive regulation of blood circulation GO:1903524 2 0.012
positive regulation of cellular biosynthetic process GO:0031328 68 0.012
cellular response to hormone stimulus GO:0032870 39 0.012
nitric oxide metabolic process GO:0046209 2 0.012
embryonic skeletal system development GO:0048706 97 0.012
glycerophospholipid biosynthetic process GO:0046474 1 0.012
regulation of fatty acid metabolic process GO:0019217 1 0.012
multicellular organismal homeostasis GO:0048871 29 0.012
ear development GO:0043583 127 0.012
positive regulation of biosynthetic process GO:0009891 68 0.012
regulation of macromolecule biosynthetic process GO:0010556 225 0.012
glial cell proliferation GO:0014009 4 0.012
muscle tissue development GO:0060537 110 0.011
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.011
positive regulation of secretion by cell GO:1903532 1 0.011
atp catabolic process GO:0006200 4 0.011
positive regulation of secretion GO:0051047 1 0.011
carbohydrate homeostasis GO:0033500 1 0.011
trabecula formation GO:0060343 2 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.011
response to nutrient levels GO:0031667 10 0.011
nucleobase containing compound biosynthetic process GO:0034654 205 0.011
protein complex biogenesis GO:0070271 30 0.011
neurological system process GO:0050877 62 0.011
Mouse
ammonium transport GO:0015696 6 0.011
sodium ion transport GO:0006814 24 0.011
regulation of mononuclear cell migration GO:0071675 1 0.011
sodium ion import GO:0097369 3 0.011
phosphate containing compound metabolic process GO:0006796 108 0.011
regulation of cell migration GO:0030334 40 0.011
Mouse
regulation of muscle contraction GO:0006937 3 0.010
positive regulation of rna biosynthetic process GO:1902680 57 0.010
establishment of endothelial barrier GO:0061028 3 0.010
amide transport GO:0042886 12 0.010
Zebrafish Mouse
muscle cell differentiation GO:0042692 139 0.010
gastrulation GO:0007369 208 0.010
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.010
glycerolipid biosynthetic process GO:0045017 1 0.010
glial cell differentiation GO:0010001 42 0.010
innate immune response GO:0045087 13 0.010
wnt signaling pathway GO:0016055 80 0.010
positive regulation of cellular amine metabolic process GO:0033240 0 0.010
positive regulation of retina development in camera type eye GO:1902868 1 0.010
cell matrix adhesion GO:0007160 4 0.010
neuromast development GO:0048884 46 0.010
regulation of rna metabolic process GO:0051252 224 0.010
cellular response to retinoic acid GO:0071300 1 0.010
regulation of cellular ketone metabolic process GO:0010565 7 0.010
regulation of protein transport GO:0051223 3 0.010

aqp1a.1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
bone disease DOID:0080001 0 0.043
disease of anatomical entity DOID:7 0 0.043
musculoskeletal system disease DOID:17 0 0.043
connective tissue disease DOID:65 0 0.043
bone remodeling disease DOID:0080005 0 0.042