Danio rerio

0 known processes

rxfp2

relaxin/insulin-like family peptide receptor 2

(Aliases: lgr8.1,zgc:63668,MGC63668)

rxfp2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of macromolecule metabolic process GO:0060255 317 0.133
nitrogen compound metabolic process GO:0006807 319 0.121
regulation of cellular metabolic process GO:0031323 320 0.102
cellular nitrogen compound biosynthetic process GO:0044271 218 0.092
larval development GO:0002164 2 0.092
cellular macromolecule metabolic process GO:0044260 391 0.087
positive regulation of muscle organ development GO:0048636 1 0.080
cellular aromatic compound metabolic process GO:0006725 295 0.079
organic cyclic compound metabolic process GO:1901360 301 0.077
maintenance of location GO:0051235 4 0.075
regulation of metabolic process GO:0019222 359 0.073
cellular nitrogen compound metabolic process GO:0034641 290 0.072
cellular biosynthetic process GO:0044249 286 0.068
regulation of primary metabolic process GO:0080090 311 0.060
nucleobase containing compound biosynthetic process GO:0034654 205 0.059
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.058
aromatic compound biosynthetic process GO:0019438 217 0.057
aging GO:0007568 2 0.053
cellular protein catabolic process GO:0044257 4 0.052
nucleobase containing compound metabolic process GO:0006139 274 0.051
carboxylic acid metabolic process GO:0019752 22 0.050
nucleic acid metabolic process GO:0090304 244 0.049
regulation of nitrogen compound metabolic process GO:0051171 251 0.049
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.049
heterocycle biosynthetic process GO:0018130 215 0.047
negative regulation of biological process GO:0048519 304 0.047
positive regulation of cellular component biogenesis GO:0044089 3 0.045
positive regulation of cellular catabolic process GO:0031331 3 0.045
proteasomal protein catabolic process GO:0010498 2 0.045
gene expression GO:0010467 252 0.044
lipid storage GO:0019915 1 0.042
transcription dna templated GO:0006351 181 0.042
positive regulation of catabolic process GO:0009896 4 0.041
regulation of gene expression GO:0010468 265 0.040
camera type eye development GO:0043010 222 0.039
regulation of rna biosynthetic process GO:2001141 213 0.038
biosynthetic process GO:0009058 294 0.038
cell surface receptor signaling pathway GO:0007166 325 0.037
Mouse
regulation of protein catabolic process GO:0042176 1 0.037
regulation of nucleic acid templated transcription GO:1903506 213 0.037
regulation of macromolecule biosynthetic process GO:0010556 225 0.037
signal transduction GO:0007165 455 0.035
Mouse
organic cyclic compound biosynthetic process GO:1901362 223 0.035
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.035
response to glucocorticoid GO:0051384 1 0.035
female sex differentiation GO:0046660 4 0.035
macromolecule biosynthetic process GO:0009059 227 0.035
small molecule metabolic process GO:0044281 77 0.034
positive regulation of biological process GO:0048518 253 0.034
regulation of circadian rhythm GO:0042752 4 0.034
protein localization to nucleus GO:0034504 3 0.033
regulation of response to stimulus GO:0048583 269 0.033
growth GO:0040007 174 0.033
organonitrogen compound metabolic process GO:1901564 74 0.033
cellular response to nutrient levels GO:0031669 2 0.033
regulation of developmental process GO:0050793 247 0.032
regulation of biological quality GO:0065008 263 0.032
rna metabolic process GO:0016070 219 0.032
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.032
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.032
cell projection morphogenesis GO:0048858 244 0.031
cellular macromolecule biosynthetic process GO:0034645 224 0.031
extrinsic apoptotic signaling pathway GO:0097191 3 0.031
skeletal system development GO:0001501 181 0.031
cellular response to extracellular stimulus GO:0031668 2 0.031
viral process GO:0016032 1 0.030
gland development GO:0048732 143 0.030
adult behavior GO:0030534 2 0.030
regulation of multicellular organismal process GO:0051239 277 0.030
positive regulation of metabolic process GO:0009893 108 0.030
regulation of binding GO:0051098 3 0.030
modification dependent protein catabolic process GO:0019941 3 0.029
negative regulation of gene expression GO:0010629 65 0.029
oxoacid metabolic process GO:0043436 31 0.029
response to uv GO:0009411 3 0.029
single organism nuclear import GO:1902593 3 0.028
protein import GO:0017038 3 0.028
cognition GO:0050890 1 0.028
stem cell proliferation GO:0072089 4 0.028
sensory organ development GO:0007423 393 0.028
single organism transport GO:0044765 206 0.028
regulation of establishment of protein localization GO:0070201 4 0.027
regulation of multicellular organismal development GO:2000026 223 0.027
tube morphogenesis GO:0035239 349 0.026
positive regulation of cellular metabolic process GO:0031325 94 0.026
cell part morphogenesis GO:0032990 246 0.026
organic acid metabolic process GO:0006082 31 0.026
response to chemical GO:0042221 320 0.026
embryonic organ development GO:0048568 381 0.026
organic substance biosynthetic process GO:1901576 289 0.025
rna biosynthetic process GO:0032774 181 0.025
response to external stimulus GO:0009605 264 0.025
establishment of localization GO:0051234 244 0.025
ubiquitin dependent protein catabolic process GO:0006511 3 0.025
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.025
establishment of protein localization to organelle GO:0072594 4 0.024
sleep GO:0030431 1 0.024
tissue remodeling GO:0048771 4 0.024
regulation of multicellular organism growth GO:0040014 4 0.024
multicellular organism growth GO:0035264 4 0.024
positive regulation of transport GO:0051050 2 0.023
apoptotic process involved in development GO:1902742 2 0.023
regulation of cellular biosynthetic process GO:0031326 245 0.023
hepaticobiliary system development GO:0061008 98 0.023
nuclear transport GO:0051169 4 0.023
response to monosaccharide GO:0034284 3 0.023
regulation of protein transport GO:0051223 3 0.023
negative regulation of macromolecule metabolic process GO:0010605 76 0.023
diencephalon development GO:0021536 58 0.023
regulation of hormone secretion GO:0046883 2 0.022
negative regulation of cellular process GO:0048523 283 0.022
regulation of signaling GO:0023051 235 0.022
positive regulation of cellular process GO:0048522 201 0.022
multi organism cellular process GO:0044764 2 0.022
protein import into nucleus GO:0006606 3 0.022
blood vessel morphogenesis GO:0048514 216 0.022
digestive system development GO:0055123 289 0.022
cell aging GO:0007569 2 0.022
regulation of synapse organization GO:0050807 3 0.022
positive regulation of rna biosynthetic process GO:1902680 57 0.022
response to carbohydrate GO:0009743 3 0.022
circadian sleep wake cycle process GO:0022410 2 0.022
cellular component movement GO:0006928 335 0.022
negative regulation of transcription dna templated GO:0045892 45 0.022
nuclear import GO:0051170 3 0.021
neuron development GO:0048666 262 0.021
response to xenobiotic stimulus GO:0009410 45 0.021
rna localization GO:0006403 4 0.021
dna templated transcription initiation GO:0006352 1 0.021
renal tubule morphogenesis GO:0061333 1 0.021
immune system process GO:0002376 241 0.021
head development GO:0060322 303 0.021
negative regulation of metabolic process GO:0009892 86 0.021
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.021
cellular response to starvation GO:0009267 1 0.021
carbohydrate derivative metabolic process GO:1901135 61 0.021
nucleic acid templated transcription GO:0097659 181 0.021
regulation of organ growth GO:0046620 3 0.021
regulation of biosynthetic process GO:0009889 250 0.021
cellular component morphogenesis GO:0032989 336 0.021
guanosine containing compound catabolic process GO:1901069 2 0.020
cellular response to external stimulus GO:0071496 2 0.020
guanosine containing compound metabolic process GO:1901068 4 0.020
regulation of gtp catabolic process GO:0033124 2 0.020
regulation of skeletal muscle tissue development GO:0048641 4 0.020
response to topologically incorrect protein GO:0035966 2 0.020
hormone secretion GO:0046879 2 0.020
heterocycle metabolic process GO:0046483 290 0.020
response to stress GO:0006950 263 0.020
modification dependent macromolecule catabolic process GO:0043632 3 0.020
sister chromatid cohesion GO:0007062 2 0.020
cellular amino acid metabolic process GO:0006520 7 0.020
positive regulation of muscle tissue development GO:1901863 1 0.020
response to corticosteroid GO:0031960 1 0.020
regulation of rna metabolic process GO:0051252 224 0.019
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.019
nucleocytoplasmic transport GO:0006913 4 0.019
regulation of cell differentiation GO:0045595 142 0.019
developmental growth GO:0048589 166 0.019
positive regulation of cell cycle GO:0045787 3 0.019
regulation of stem cell proliferation GO:0072091 2 0.019
estrogen metabolic process GO:0008210 2 0.019
cell morphogenesis GO:0000902 289 0.019
cellular ketone metabolic process GO:0042180 11 0.019
transcription from rna polymerase ii promoter GO:0006366 80 0.019
neuroblast proliferation GO:0007405 2 0.019
generation of neurons GO:0048699 385 0.019
muscle organ development GO:0007517 101 0.019
response to radiation GO:0009314 51 0.019
digestive tract development GO:0048565 265 0.018
phosphate containing compound metabolic process GO:0006796 108 0.018
amine metabolic process GO:0009308 2 0.018
regionalization GO:0003002 274 0.018
secondary metabolic process GO:0019748 3 0.018
regulation of cell communication GO:0010646 232 0.018
positive regulation of striated muscle tissue development GO:0045844 1 0.018
odontogenesis of dentin containing tooth GO:0042475 1 0.018
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.018
negative regulation of secretion GO:0051048 2 0.018
glucose homeostasis GO:0042593 1 0.018
hemopoiesis GO:0030097 183 0.018
cell projection organization GO:0030030 284 0.018
regulation of transcription dna templated GO:0006355 213 0.018
lipid metabolic process GO:0006629 52 0.018
g1 s transition of mitotic cell cycle GO:0000082 1 0.018
cellular response to topologically incorrect protein GO:0035967 2 0.017
regulation of dendrite development GO:0050773 3 0.017
central nervous system development GO:0007417 387 0.017
gtp catabolic process GO:0006184 2 0.017
cellular amine metabolic process GO:0044106 2 0.017
phagocytosis GO:0006909 3 0.017
negative regulation of biosynthetic process GO:0009890 55 0.017
regulation of cell activation GO:0050865 1 0.017
gtp metabolic process GO:0046039 4 0.017
nuclear export GO:0051168 1 0.017
regulation of nervous system development GO:0051960 90 0.016
xenobiotic metabolic process GO:0006805 4 0.016
cytokinesis GO:0000910 3 0.016
cellular response to unfolded protein GO:0034620 2 0.016
cell motility GO:0048870 244 0.016
nephron epithelium morphogenesis GO:0072088 1 0.016
eye development GO:0001654 277 0.016
cell cycle g1 s phase transition GO:0044843 1 0.016
er nucleus signaling pathway GO:0006984 2 0.016
wnt signaling pathway GO:0016055 80 0.016
nephron morphogenesis GO:0072028 2 0.016
regulation of signal transduction GO:0009966 225 0.016
regulation of cytoplasmic transport GO:1903649 4 0.016
mesenchyme development GO:0060485 127 0.015
regulation of nucleotide catabolic process GO:0030811 2 0.015
protein targeting to nucleus GO:0044744 3 0.015
multi organism process GO:0051704 134 0.015
retina development in camera type eye GO:0060041 146 0.015
nephron tubule morphogenesis GO:0072078 1 0.015
signal transduction in absence of ligand GO:0038034 1 0.015
response to glucose GO:0009749 3 0.015
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.015
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.015
death GO:0016265 121 0.015
regulation of cell death GO:0010941 103 0.015
positive regulation of biosynthetic process GO:0009891 68 0.015
embryo development ending in birth or egg hatching GO:0009792 271 0.015
vasculature development GO:0001944 278 0.014
negative regulation of protein phosphorylation GO:0001933 4 0.014
hematopoietic or lymphoid organ development GO:0048534 191 0.014
cell death GO:0008219 121 0.014
regulation of cellular ketone metabolic process GO:0010565 7 0.014
endoplasmic reticulum unfolded protein response GO:0030968 2 0.014
response to hexose GO:0009746 3 0.014
ventricular cardiac muscle tissue development GO:0003229 3 0.014
brain development GO:0007420 293 0.014
carbohydrate homeostasis GO:0033500 1 0.014
cellular component assembly GO:0022607 170 0.014
heart development GO:0007507 313 0.014
regulation of protein binding GO:0043393 3 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.014
transport GO:0006810 220 0.014
lipid oxidation GO:0034440 1 0.014
interspecies interaction between organisms GO:0044419 4 0.014
positive regulation of apoptotic signaling pathway GO:2001235 1 0.014
negative regulation of secretion by cell GO:1903531 2 0.013
negative regulation of cellular catabolic process GO:0031330 3 0.013
positive regulation of cellular carbohydrate metabolic process GO:0010676 1 0.013
astrocyte differentiation GO:0048708 1 0.013
organelle assembly GO:0070925 110 0.013
regulation of cellular protein catabolic process GO:1903362 1 0.013
protein secretion GO:0009306 1 0.013
protein acetylation GO:0006473 2 0.013
regulation of metal ion transport GO:0010959 4 0.013
regulation of cytokine mediated signaling pathway GO:0001959 3 0.013
protein metabolic process GO:0019538 183 0.013
digestive tract morphogenesis GO:0048546 231 0.013
cell migration GO:0016477 237 0.013
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.013
neuron differentiation GO:0030182 353 0.013
regulation of protein complex assembly GO:0043254 3 0.013
regulation of nucleoside metabolic process GO:0009118 2 0.013
developmental programmed cell death GO:0010623 4 0.013
response to oxygen levels GO:0070482 25 0.013
exocytosis GO:0006887 1 0.013
cellular response to chemical stimulus GO:0070887 157 0.013
regulation of molecular function GO:0065009 70 0.013
protein homooligomerization GO:0051260 3 0.013
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 4 0.013
regulation of purine nucleotide catabolic process GO:0033121 2 0.013
regulation of translational initiation GO:0006446 1 0.013
synaptic growth at neuromuscular junction GO:0051124 2 0.013
ear development GO:0043583 127 0.013
regulation of cellular amine metabolic process GO:0033238 0 0.013
macromolecule modification GO:0043412 111 0.012
atp catabolic process GO:0006200 4 0.012
blood vessel development GO:0001568 246 0.012
negative regulation of intracellular transport GO:0032387 3 0.012
intracellular signal transduction GO:0035556 85 0.012
regulation of tube size GO:0035150 2 0.012
lateral inhibition GO:0046331 1 0.012
neuromuscular synaptic transmission GO:0007274 2 0.012
epithelial cell differentiation GO:0030855 116 0.012
response to light stimulus GO:0009416 46 0.012
cellular component biogenesis GO:0044085 178 0.012
b cell activation GO:0042113 2 0.012
neuron projection morphogenesis GO:0048812 161 0.012
interaction with host GO:0051701 4 0.012
negative regulation of cellular biosynthetic process GO:0031327 55 0.012
single organism metabolic process GO:0044710 217 0.012
ribonucleoside monophosphate catabolic process GO:0009158 4 0.012
anterior posterior pattern specification GO:0009952 152 0.012
mitochondrion organization GO:0007005 4 0.012
modification of morphology or physiology of other organism GO:0035821 4 0.012
mitotic dna damage checkpoint GO:0044773 4 0.012
negative regulation of protein transport GO:0051224 3 0.012
enzyme linked receptor protein signaling pathway GO:0007167 106 0.012
neurotransmitter transport GO:0006836 2 0.012
regulation of epithelial cell proliferation GO:0050678 3 0.012
regulation of organelle assembly GO:1902115 4 0.012
negative regulation of cellular metabolic process GO:0031324 77 0.012
positive regulation of cellular biosynthetic process GO:0031328 68 0.011
hypothalamus cell differentiation GO:0021979 4 0.011
connective tissue development GO:0061448 99 0.011
negative regulation of apoptotic process GO:0043066 55 0.011
locomotion GO:0040011 313 0.011
positive regulation of multicellular organismal process GO:0051240 52 0.011
homeostatic process GO:0042592 142 0.011
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.011
meiotic cell cycle process GO:1903046 3 0.011
apoptotic process GO:0006915 116 0.011
response to unfolded protein GO:0006986 2 0.011
autophagy GO:0006914 4 0.011
positive regulation of nucleoside metabolic process GO:0045979 1 0.011
response to wounding GO:0009611 116 0.011
negative regulation of nucleic acid templated transcription GO:1903507 45 0.011
cellular response to oxygen levels GO:0071453 1 0.011
embryonic limb morphogenesis GO:0030326 2 0.011
carbohydrate biosynthetic process GO:0016051 1 0.011
localization of cell GO:0051674 244 0.011
regulation of synapse assembly GO:0051963 3 0.011
locomotor rhythm GO:0045475 3 0.011
regeneration GO:0031099 91 0.011
regulation of dendrite morphogenesis GO:0048814 3 0.011
positive regulation of signal transduction GO:0009967 56 0.011
regulation of cell development GO:0060284 100 0.011
regulation of neurotransmitter transport GO:0051588 1 0.011
chordate embryonic development GO:0043009 271 0.011
meiosis i GO:0007127 1 0.011
cellular lipid metabolic process GO:0044255 36 0.011
regulation of apoptotic process GO:0042981 98 0.011
positive regulation of dna metabolic process GO:0051054 1 0.011
phosphorus metabolic process GO:0006793 109 0.011
alpha amino acid metabolic process GO:1901605 3 0.011
positive regulation of stem cell proliferation GO:2000648 1 0.010
phosphorylation GO:0016310 69 0.010
cellular response to xenobiotic stimulus GO:0071466 35 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.010
cellular response to hypoxia GO:0071456 1 0.010
tissue regeneration GO:0042246 74 0.010
negative regulation of rna metabolic process GO:0051253 48 0.010
single organism localization GO:1902578 225 0.010
striated muscle tissue development GO:0014706 110 0.010
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.010
regulation of chromosome segregation GO:0051983 1 0.010
dna templated transcription elongation GO:0006354 3 0.010
cell fate commitment GO:0045165 99 0.010
positive regulation of macromolecule metabolic process GO:0010604 93 0.010
protein heterooligomerization GO:0051291 1 0.010
morphogenesis of an epithelium GO:0002009 333 0.010
peptide transport GO:0015833 1 0.010
regulation of cytokine production GO:0001817 3 0.010
response to alkaloid GO:0043279 2 0.010
multicellular organismal response to stress GO:0033555 2 0.010
embryonic organ morphogenesis GO:0048562 274 0.010
pyruvate metabolic process GO:0006090 1 0.010
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.010
negative regulation of catabolic process GO:0009895 3 0.010
fertilization GO:0009566 3 0.010
cellular response to stress GO:0033554 62 0.010

rxfp2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
disease of cellular proliferation DOID:14566 0 0.015
disease of metabolism DOID:0014667 0 0.013
cancer DOID:162 0 0.012
organ system cancer DOID:0050686 0 0.012