Danio rerio

0 known processes

syvn1

synovial apoptosis inhibitor 1, synoviolin

(Aliases: wu:fk91f10,zgc:55735,zgc:77108)

syvn1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular protein catabolic process GO:0044257 4 0.528
Human
modification dependent protein catabolic process GO:0019941 3 0.338
Human
ubiquitin dependent protein catabolic process GO:0006511 3 0.296
Human
cellular response to topologically incorrect protein GO:0035967 2 0.273
proteasomal protein catabolic process GO:0010498 2 0.264
Human
cellular macromolecule metabolic process GO:0044260 391 0.259
Human
lipid storage GO:0019915 1 0.228
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.220
Human
modification dependent macromolecule catabolic process GO:0043632 3 0.218
Human
cellular protein metabolic process GO:0044267 129 0.176
Human
embryonic organ development GO:0048568 381 0.174
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.165
Human
response to chemical GO:0042221 320 0.127
response to topologically incorrect protein GO:0035966 2 0.104
er nucleus signaling pathway GO:0006984 2 0.101
cellular transition metal ion homeostasis GO:0046916 3 0.095
cellular response to external stimulus GO:0071496 2 0.086
cellular macromolecule catabolic process GO:0044265 12 0.085
Human
regulation of cellular metabolic process GO:0031323 320 0.082
response to endoplasmic reticulum stress GO:0034976 6 0.071
Mouse
maintenance of location GO:0051235 4 0.071
regulation of signaling GO:0023051 235 0.069
Mouse
aging GO:0007568 2 0.064
response to stress GO:0006950 263 0.064
Mouse
response to unfolded protein GO:0006986 2 0.063
larval development GO:0002164 2 0.062
cellular response to chemical stimulus GO:0070887 157 0.055
negative regulation of cell communication GO:0010648 96 0.050
Mouse
protein metabolic process GO:0019538 183 0.050
Human
regulation of signal transduction GO:0009966 225 0.050
Mouse
cellular component assembly GO:0022607 170 0.048
multicellular organism growth GO:0035264 4 0.047
establishment of protein localization to organelle GO:0072594 4 0.046
positive regulation of catabolic process GO:0009896 4 0.044
cellular aromatic compound metabolic process GO:0006725 295 0.044
golgi vesicle transport GO:0048193 3 0.043
proteolysis GO:0006508 38 0.043
Human
signal transduction GO:0007165 455 0.042
Mouse
positive regulation of cellular catabolic process GO:0031331 3 0.042
response to organic substance GO:0010033 153 0.041
endoplasmic reticulum unfolded protein response GO:0030968 2 0.040
autophagy GO:0006914 4 0.040
regulation of cell death GO:0010941 103 0.039
Mouse
organic substance biosynthetic process GO:1901576 289 0.039
Human
cellular response to unfolded protein GO:0034620 2 0.038
chordate embryonic development GO:0043009 271 0.038
Mouse
regulation of biological quality GO:0065008 263 0.036
regulation of multicellular organism growth GO:0040014 4 0.036
positive regulation of transport GO:0051050 2 0.036
homeostatic process GO:0042592 142 0.036
cellular response to starvation GO:0009267 1 0.035
response to abiotic stimulus GO:0009628 122 0.034
cellular response to organic substance GO:0071310 105 0.033
negative regulation of cellular process GO:0048523 283 0.033
Mouse
locomotion GO:0040011 313 0.033
nitrogen compound metabolic process GO:0006807 319 0.033
cellular biosynthetic process GO:0044249 286 0.033
Human
negative regulation of protein phosphorylation GO:0001933 4 0.032
meiotic cell cycle process GO:1903046 3 0.032
cellular response to nutrient levels GO:0031669 2 0.030
negative regulation of kinase activity GO:0033673 4 0.030
specification of symmetry GO:0009799 204 0.030
apoptotic process GO:0006915 116 0.030
Mouse
acylglycerol homeostasis GO:0055090 2 0.029
cell death GO:0008219 121 0.029
Mouse
positive regulation of apoptotic signaling pathway GO:2001235 1 0.029
organic substance catabolic process GO:1901575 28 0.029
Human
positive regulation of cellular metabolic process GO:0031325 94 0.029
organelle organization GO:0006996 227 0.028
negative regulation of catabolic process GO:0009895 3 0.028
cellular response to stress GO:0033554 62 0.028
Mouse
regulation of cellular ketone metabolic process GO:0010565 7 0.028
negative regulation of cellular catabolic process GO:0031330 3 0.027
regulation of protein catabolic process GO:0042176 1 0.027
notochord development GO:0030903 54 0.027
response to antibiotic GO:0046677 1 0.027
regulation of metabolic process GO:0019222 359 0.027
regulation of response to stimulus GO:0048583 269 0.026
Mouse
tube morphogenesis GO:0035239 349 0.026
regulation of cell communication GO:0010646 232 0.026
Mouse
regulation of multicellular organismal process GO:0051239 277 0.026
embryo development ending in birth or egg hatching GO:0009792 271 0.026
Mouse
programmed cell death GO:0012501 119 0.026
Mouse
cell migration GO:0016477 237 0.025
determination of left right symmetry GO:0007368 179 0.025
single organism localization GO:1902578 225 0.024
death GO:0016265 121 0.024
Mouse
cellular amide metabolic process GO:0043603 4 0.024
immune system development GO:0002520 191 0.024
regulation of gene expression GO:0010468 265 0.024
aromatic compound biosynthetic process GO:0019438 217 0.023
positive regulation of secretion by cell GO:1903532 1 0.023
regulation of blood vessel size GO:0050880 2 0.023
cellular component morphogenesis GO:0032989 336 0.023
er to golgi vesicle mediated transport GO:0006888 1 0.023
sensory organ development GO:0007423 393 0.023
collagen metabolic process GO:0032963 2 0.022
transport GO:0006810 220 0.022
phagocytosis GO:0006909 3 0.022
negative regulation of response to cytokine stimulus GO:0060761 2 0.022
response to other organism GO:0051707 97 0.021
regulation of blood pressure GO:0008217 1 0.021
epithelial cell differentiation GO:0030855 116 0.021
cell surface receptor signaling pathway GO:0007166 325 0.021
regulation of tube size GO:0035150 2 0.021
transcription from rna polymerase ii promoter GO:0006366 80 0.021
catabolic process GO:0009056 32 0.020
Human
regulation of macromolecule biosynthetic process GO:0010556 225 0.020
regulation of metal ion transport GO:0010959 4 0.020
regulation of cellular biosynthetic process GO:0031326 245 0.020
cell substrate junction assembly GO:0007044 2 0.020
epithelial cell morphogenesis GO:0003382 2 0.020
fin development GO:0033333 77 0.020
small molecule metabolic process GO:0044281 77 0.020
enzyme linked receptor protein signaling pathway GO:0007167 106 0.020
cell morphogenesis GO:0000902 289 0.020
regulation of nitrogen compound metabolic process GO:0051171 251 0.019
response to carbohydrate GO:0009743 3 0.019
embryonic organ morphogenesis GO:0048562 274 0.019
negative regulation of protein kinase activity GO:0006469 4 0.019
determination of bilateral symmetry GO:0009855 204 0.019
skeletal system development GO:0001501 181 0.019
positive regulation of secretion GO:0051047 1 0.019
regulation of biosynthetic process GO:0009889 250 0.019
centrosome cycle GO:0007098 1 0.019
single organism metabolic process GO:0044710 217 0.019
Human
meiotic nuclear division GO:0007126 4 0.018
regulation of protein ubiquitination GO:0031396 3 0.018
gtp metabolic process GO:0046039 4 0.018
regulation of purine nucleotide catabolic process GO:0033121 2 0.018
response to endogenous stimulus GO:0009719 83 0.018
hormone biosynthetic process GO:0042446 3 0.018
negative regulation of mapk cascade GO:0043409 4 0.018
organic cyclic compound metabolic process GO:1901360 301 0.018
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.018
regulation of protein transport GO:0051223 3 0.017
regulation of epithelial cell proliferation GO:0050678 3 0.017
cellular component biogenesis GO:0044085 178 0.017
cellular protein modification process GO:0006464 100 0.017
Human
positive regulation of macromolecule metabolic process GO:0010604 93 0.017
sensory organ morphogenesis GO:0090596 200 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
erk1 and erk2 cascade GO:0070371 4 0.017
regulation of developmental process GO:0050793 247 0.017
immune system process GO:0002376 241 0.017
regulation of gtpase activity GO:0043087 2 0.017
amine metabolic process GO:0009308 2 0.017
regulation of cell activation GO:0050865 1 0.017
extrinsic apoptotic signaling pathway GO:0097191 3 0.016
regulation of nucleoside metabolic process GO:0009118 2 0.016
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.016
regulation of nucleotide catabolic process GO:0030811 2 0.016
regulation of cytokine mediated signaling pathway GO:0001959 3 0.016
nucleobase containing compound metabolic process GO:0006139 274 0.016
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.016
production of molecular mediator of immune response GO:0002440 2 0.016
regulation of inflammatory response GO:0050727 2 0.016
multicellular organismal metabolic process GO:0044236 2 0.016
growth GO:0040007 174 0.015
protein heterooligomerization GO:0051291 1 0.015
biosynthetic process GO:0009058 294 0.015
Human
gtp catabolic process GO:0006184 2 0.015
protein dephosphorylation GO:0006470 3 0.015
guanosine containing compound catabolic process GO:1901069 2 0.015
response to hormone GO:0009725 48 0.015
cellular response to extracellular stimulus GO:0031668 2 0.015
regulation of macromolecule metabolic process GO:0060255 317 0.015
negative regulation of signaling GO:0023057 96 0.015
Mouse
cellular nitrogen compound metabolic process GO:0034641 290 0.015
digestive system development GO:0055123 289 0.015
cellular nitrogen compound biosynthetic process GO:0044271 218 0.015
regulation of autophagy GO:0010506 3 0.015
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.014
heart development GO:0007507 313 0.014
organonitrogen compound metabolic process GO:1901564 74 0.014
protein import GO:0017038 3 0.014
morphogenesis of an epithelium GO:0002009 333 0.014
mesoderm development GO:0007498 88 0.014
single organism organelle organization GO:1902589 199 0.014
cellular ketone metabolic process GO:0042180 11 0.014
cell part morphogenesis GO:0032990 246 0.014
heterocycle metabolic process GO:0046483 290 0.014
iron ion homeostasis GO:0055072 4 0.014
response to biotic stimulus GO:0009607 97 0.014
cellular response to organic cyclic compound GO:0071407 38 0.014
protein targeting to membrane GO:0006612 1 0.014
b cell activation GO:0042113 2 0.014
response to decreased oxygen levels GO:0036293 25 0.013
regulation of primary metabolic process GO:0080090 311 0.013
female meiotic division GO:0007143 2 0.013
response to organic cyclic compound GO:0014070 51 0.013
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.013
epithelial tube morphogenesis GO:0060562 148 0.013
regulation of cellular amine metabolic process GO:0033238 0 0.013
developmental growth GO:0048589 166 0.013
regulation of apoptotic process GO:0042981 98 0.013
Mouse
hormone secretion GO:0046879 2 0.012
positive regulation of cellular protein metabolic process GO:0032270 22 0.012
protein modification process GO:0036211 100 0.012
Human
toxin transport GO:1901998 2 0.012
cellular modified amino acid metabolic process GO:0006575 3 0.012
cellular catabolic process GO:0044248 27 0.012
Human
determination of heart left right asymmetry GO:0061371 117 0.012
head development GO:0060322 303 0.012
regulation of ph GO:0006885 3 0.012
cellular response to endogenous stimulus GO:0071495 68 0.012
regulation of intracellular signal transduction GO:1902531 57 0.012
Mouse
regulation of cytokine production GO:0001817 3 0.012
regulation of establishment of protein localization GO:0070201 4 0.012
nuclear export GO:0051168 1 0.012
digestive tract morphogenesis GO:0048546 231 0.012
regulation of programmed cell death GO:0043067 101 0.012
Mouse
carbohydrate homeostasis GO:0033500 1 0.012
negative regulation of response to stimulus GO:0048585 104 0.012
Mouse
regulation of glucose transport GO:0010827 1 0.012
regionalization GO:0003002 274 0.011
cellular amino acid metabolic process GO:0006520 7 0.011
regulation of protein metabolic process GO:0051246 56 0.011
negative regulation of epithelial cell proliferation GO:0050680 1 0.011
system process GO:0003008 185 0.011
intracellular signal transduction GO:0035556 85 0.011
Mouse
regulation of multicellular organismal development GO:2000026 223 0.011
organonitrogen compound biosynthetic process GO:1901566 47 0.011
macroautophagy GO:0016236 1 0.011
cilium morphogenesis GO:0060271 85 0.011
heart looping GO:0001947 94 0.011
positive regulation of signaling GO:0023056 56 0.011
axon cargo transport GO:0008088 2 0.011
regulation of production of molecular mediator of immune response GO:0002700 1 0.011
negative regulation of programmed cell death GO:0043069 58 0.011
Mouse
peptide transport GO:0015833 1 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.011
cellular amine metabolic process GO:0044106 2 0.011
establishment or maintenance of polarity of embryonic epithelium GO:0016332 2 0.011
hormone transport GO:0009914 2 0.011
response to estrogen GO:0043627 27 0.011
establishment of localization GO:0051234 244 0.011
protein secretion GO:0009306 1 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.011
embryonic heart tube morphogenesis GO:0003143 108 0.011
regulation of nucleic acid templated transcription GO:1903506 213 0.011
cell cycle GO:0007049 93 0.011
regulation of synapse organization GO:0050807 3 0.011
protein polyubiquitination GO:0000209 4 0.011
cellular response to biotic stimulus GO:0071216 3 0.011
cellular respiration GO:0045333 3 0.010
phosphatidylinositol mediated signaling GO:0048015 2 0.010
cell projection organization GO:0030030 284 0.010
defense response to fungus GO:0050832 2 0.010
peptide metabolic process GO:0006518 1 0.010
oxoacid metabolic process GO:0043436 31 0.010
regulation of response to extracellular stimulus GO:0032104 1 0.010
response to nutrient GO:0007584 3 0.010
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.010
extracellular matrix organization GO:0030198 27 0.010
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.010
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.010
regulation of transcription dna templated GO:0006355 213 0.010
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.010
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.010
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.010
single organism nuclear import GO:1902593 3 0.010
gland development GO:0048732 143 0.010
transmembrane transport GO:0055085 120 0.010
dna templated transcription elongation GO:0006354 3 0.010

syvn1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.039
disease of cellular proliferation DOID:14566 0 0.024
cancer DOID:162 0 0.023
organ system cancer DOID:0050686 0 0.016
nervous system disease DOID:863 0 0.016
musculoskeletal system disease DOID:17 0 0.014
endocrine gland cancer DOID:170 0 0.013
endocrine system disease DOID:28 0 0.010
retinal disease DOID:5679 0 0.010
sensory system disease DOID:0050155 0 0.010
eye and adnexa disease DOID:1492 0 0.010
eye disease DOID:5614 0 0.010