Danio rerio

0 known processes

nck2b

NCK adaptor protein 2b

(Aliases: zgc:92024,im:7147817,wu:fd20h08,si:ch211-147g19.3,fd20h08)

nck2b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.108
signal transduction GO:0007165 455 0.086
Fly
response to external stimulus GO:0009605 264 0.071
Fly
negative regulation of biological process GO:0048519 304 0.065
Fly
regulation of response to stimulus GO:0048583 269 0.059
Fly
localization of cell GO:0051674 244 0.056
Mouse
regionalization GO:0003002 274 0.056
nitrogen compound metabolic process GO:0006807 319 0.054
Human
maintenance of location GO:0051235 4 0.054
regulation of synapse assembly GO:0051963 3 0.053
negative regulation of cellular process GO:0048523 283 0.053
Fly
gene expression GO:0010467 252 0.053
Human
immune system process GO:0002376 241 0.051
Human
cellular nitrogen compound metabolic process GO:0034641 290 0.050
Human
establishment of localization GO:0051234 244 0.049
cellular macromolecule metabolic process GO:0044260 391 0.049
Human
regulation of nitrogen compound metabolic process GO:0051171 251 0.048
Human
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.044
cellular macromolecule biosynthetic process GO:0034645 224 0.043
Human
regulation of signal transduction GO:0009966 225 0.042
Fly
protein acetylation GO:0006473 2 0.041
lipid storage GO:0019915 1 0.041
single organism organelle organization GO:1902589 199 0.040
Human Mouse
regulation of cellular metabolic process GO:0031323 320 0.039
Human
regulation of macromolecule metabolic process GO:0060255 317 0.038
Human
regulation of primary metabolic process GO:0080090 311 0.037
Human
negative regulation of protein phosphorylation GO:0001933 4 0.037
determination of bilateral symmetry GO:0009855 204 0.036
cellular biosynthetic process GO:0044249 286 0.035
Human
cell part morphogenesis GO:0032990 246 0.035
Fly
response to stress GO:0006950 263 0.035
digestive system development GO:0055123 289 0.035
regulation of biological quality GO:0065008 263 0.035
Human
organelle organization GO:0006996 227 0.034
Human Mouse
single organism metabolic process GO:0044710 217 0.034
organic substance biosynthetic process GO:1901576 289 0.034
Human
regulation of cell communication GO:0010646 232 0.033
Fly
regulation of establishment of protein localization GO:0070201 4 0.033
cell surface receptor signaling pathway GO:0007166 325 0.033
Fly
cell morphogenesis GO:0000902 289 0.033
Fly
cellular nitrogen compound biosynthetic process GO:0044271 218 0.033
Human
protein polymerization GO:0051258 4 0.033
Human
specification of symmetry GO:0009799 204 0.032
heterocycle metabolic process GO:0046483 290 0.031
Human
regulation of protein transport GO:0051223 3 0.031
positive regulation of transport GO:0051050 2 0.031
nucleic acid metabolic process GO:0090304 244 0.030
Human
actin polymerization or depolymerization GO:0008154 2 0.030
Human
positive regulation of stress activated mapk cascade GO:0032874 3 0.030
regulation of protein complex assembly GO:0043254 3 0.029
Human
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.029
aromatic compound biosynthetic process GO:0019438 217 0.029
Human
cellular component movement GO:0006928 335 0.029
Mouse Fly
negative regulation of metabolic process GO:0009892 86 0.029
establishment of protein localization to organelle GO:0072594 4 0.029
response to other organism GO:0051707 97 0.029
response to drug GO:0042493 3 0.028
cell projection morphogenesis GO:0048858 244 0.028
Fly
regulation of multicellular organismal process GO:0051239 277 0.028
nuclear transport GO:0051169 4 0.028
synaptic growth at neuromuscular junction GO:0051124 2 0.027
response to external biotic stimulus GO:0043207 97 0.027
cellular component morphogenesis GO:0032989 336 0.027
Fly
regulation of multicellular organism growth GO:0040014 4 0.026
cellular amine metabolic process GO:0044106 2 0.026
gastrulation GO:0007369 208 0.026
nucleobase containing compound metabolic process GO:0006139 274 0.026
Human
protein localization to nucleus GO:0034504 3 0.026
internal protein amino acid acetylation GO:0006475 2 0.026
morphogenesis of an epithelium GO:0002009 333 0.026
peptidyl lysine acetylation GO:0018394 2 0.026
regulation of signaling GO:0023051 235 0.026
Fly
positive regulation of biological process GO:0048518 253 0.025
Human
regulation of stem cell differentiation GO:2000736 4 0.025
organic cyclic compound metabolic process GO:1901360 301 0.025
Human
cell cycle g1 s phase transition GO:0044843 1 0.025
negative regulation of synapse assembly GO:0051964 2 0.025
regulation of gene expression GO:0010468 265 0.025
Human
phagocytosis GO:0006909 3 0.025
carboxylic acid metabolic process GO:0019752 22 0.025
regulation of reproductive process GO:2000241 4 0.025
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.024
protein acylation GO:0043543 3 0.024
regulation of rna biosynthetic process GO:2001141 213 0.024
Human
response to chemical GO:0042221 320 0.024
Fly
epithelial tube morphogenesis GO:0060562 148 0.024
guanosine containing compound metabolic process GO:1901068 4 0.024
multicellular organism growth GO:0035264 4 0.024
organic acid metabolic process GO:0006082 31 0.024
organonitrogen compound metabolic process GO:1901564 74 0.024
homeostatic process GO:0042592 142 0.023
internal peptidyl lysine acetylation GO:0018393 2 0.023
actin filament polymerization GO:0030041 2 0.023
Human
nucleocytoplasmic transport GO:0006913 4 0.023
enzyme linked receptor protein signaling pathway GO:0007167 106 0.023
Fly
positive regulation of jnk cascade GO:0046330 3 0.023
regulation of nucleic acid templated transcription GO:1903506 213 0.023
Human
ribonucleoside monophosphate catabolic process GO:0009158 4 0.023
amine metabolic process GO:0009308 2 0.023
oxoacid metabolic process GO:0043436 31 0.023
cellular component biogenesis GO:0044085 178 0.022
Human Mouse
embryonic organ development GO:0048568 381 0.022
regulation of cellular biosynthetic process GO:0031326 245 0.022
Human
digestive tract development GO:0048565 265 0.022
small molecule metabolic process GO:0044281 77 0.022
protein modification process GO:0036211 100 0.021
regulation of jun kinase activity GO:0043506 3 0.021
cellular amino acid metabolic process GO:0006520 7 0.021
regulation of cell shape GO:0008360 1 0.021
regulation of biosynthetic process GO:0009889 250 0.021
Human
hemopoiesis GO:0030097 183 0.021
central nervous system development GO:0007417 387 0.021
regulation of synapse organization GO:0050807 3 0.020
negative regulation of macromolecule metabolic process GO:0010605 76 0.020
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
protein metabolic process GO:0019538 183 0.020
blood vessel morphogenesis GO:0048514 216 0.020
digestive tract morphogenesis GO:0048546 231 0.020
cell migration GO:0016477 237 0.020
Mouse
biosynthetic process GO:0009058 294 0.020
Human
cell motility GO:0048870 244 0.020
Mouse
negative regulation of kinase activity GO:0033673 4 0.020
single organism localization GO:1902578 225 0.020
blood vessel development GO:0001568 246 0.019
heart development GO:0007507 313 0.019
regulation of nucleoside metabolic process GO:0009118 2 0.019
regulation of binding GO:0051098 3 0.019
extrinsic apoptotic signaling pathway GO:0097191 3 0.019
tube morphogenesis GO:0035239 349 0.019
cellular aromatic compound metabolic process GO:0006725 295 0.019
Human
regulation of cellular ketone metabolic process GO:0010565 7 0.019
positive regulation of cell cycle GO:0045787 3 0.019
determination of left right symmetry GO:0007368 179 0.019
regulation of metabolic process GO:0019222 359 0.019
Human
wnt signaling pathway GO:0016055 80 0.019
stem cell maintenance GO:0019827 4 0.019
regulation of protein polymerization GO:0032271 2 0.018
Human
response to biotic stimulus GO:0009607 97 0.018
sensory organ development GO:0007423 393 0.018
nucleobase containing compound biosynthetic process GO:0034654 205 0.018
Human
female sex differentiation GO:0046660 4 0.018
g1 s transition of mitotic cell cycle GO:0000082 1 0.018
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.018
Human
neuron differentiation GO:0030182 353 0.018
Fly
macromolecule modification GO:0043412 111 0.018
cell projection organization GO:0030030 284 0.018
Mouse Fly
regulation of dna replication GO:0006275 3 0.018
rna metabolic process GO:0016070 219 0.018
Human
embryo development ending in birth or egg hatching GO:0009792 271 0.017
positive regulation of map kinase activity GO:0043406 3 0.017
regulation of cytoplasmic transport GO:1903649 4 0.017
single organism nuclear import GO:1902593 3 0.017
kidney development GO:0001822 92 0.017
macromolecule biosynthetic process GO:0009059 227 0.017
Human
muscle structure development GO:0061061 196 0.017
Fly
anterior posterior pattern specification GO:0009952 152 0.017
membrane fusion GO:0061025 2 0.017
positive regulation of rna metabolic process GO:0051254 59 0.017
Human
single organism membrane fusion GO:0044801 2 0.017
regulation of transcription dna templated GO:0006355 213 0.017
Human
aging GO:0007568 2 0.017
heterocycle biosynthetic process GO:0018130 215 0.016
Human
positive regulation of catabolic process GO:0009896 4 0.016
regulation of cell projection assembly GO:0060491 4 0.016
positive regulation of reproductive process GO:2000243 2 0.016
regulation of nucleocytoplasmic transport GO:0046822 2 0.016
locomotion GO:0040011 313 0.016
Mouse Fly
death GO:0016265 121 0.016
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.016
response to monosaccharide GO:0034284 3 0.016
multi organism process GO:0051704 134 0.016
response to fluid shear stress GO:0034405 2 0.016
phosphate containing compound metabolic process GO:0006796 108 0.016
purine nucleoside monophosphate catabolic process GO:0009128 4 0.016
negative regulation of cellular metabolic process GO:0031324 77 0.016
protein targeting to nucleus GO:0044744 3 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.016
Human
gtp catabolic process GO:0006184 2 0.016
dna templated transcription initiation GO:0006352 1 0.016
negative regulation of cell communication GO:0010648 96 0.016
Fly
negative regulation of dna metabolic process GO:0051053 4 0.016
phosphorus metabolic process GO:0006793 109 0.016
heart looping GO:0001947 94 0.016
response to organic substance GO:0010033 153 0.016
Fly
negative regulation of gene expression GO:0010629 65 0.016
stem cell proliferation GO:0072089 4 0.016
transcription dna templated GO:0006351 181 0.015
Human
neuron projection morphogenesis GO:0048812 161 0.015
Fly
behavior GO:0007610 74 0.015
lateral inhibition GO:0046331 1 0.015
transport GO:0006810 220 0.015
neuroblast proliferation GO:0007405 2 0.015
germ line stem cell maintenance GO:0030718 2 0.015
rna biosynthetic process GO:0032774 181 0.015
Human
regulation of chondrocyte differentiation GO:0032330 1 0.015
response to uv GO:0009411 3 0.015
cognition GO:0050890 1 0.015
negative regulation of cellular biosynthetic process GO:0031327 55 0.015
protein import GO:0017038 3 0.015
organic cyclic compound biosynthetic process GO:1901362 223 0.015
Human
nuclear import GO:0051170 3 0.015
meiotic nuclear division GO:0007126 4 0.015
carbohydrate biosynthetic process GO:0016051 1 0.015
determination of ventral identity GO:0048264 21 0.015
regulation of protein localization to nucleus GO:1900180 2 0.015
determination of heart left right asymmetry GO:0061371 117 0.014
central nervous system neuron differentiation GO:0021953 74 0.014
intracellular signal transduction GO:0035556 85 0.014
protein import into nucleus GO:0006606 3 0.014
odontogenesis of dentin containing tooth GO:0042475 1 0.014
negative regulation of protein complex assembly GO:0031333 1 0.014
single organism transport GO:0044765 206 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
regulation of cellular amine metabolic process GO:0033238 0 0.014
regulation of rna metabolic process GO:0051252 224 0.014
Human
cellular protein modification process GO:0006464 100 0.014
gtp metabolic process GO:0046039 4 0.014
nucleoside monophosphate catabolic process GO:0009125 4 0.014
mononuclear cell proliferation GO:0032943 1 0.014
Human
cellular ketone metabolic process GO:0042180 11 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.013
regulation of protein import into nucleus GO:0042306 2 0.013
negative regulation of developmental process GO:0051093 65 0.013
cell projection assembly GO:0030031 64 0.013
Mouse
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.013
Fly
positive regulation of cellular catabolic process GO:0031331 3 0.013
regulation of multicellular organismal development GO:2000026 223 0.013
organelle assembly GO:0070925 110 0.013
regulation of macromolecule biosynthetic process GO:0010556 225 0.013
Human
chemosensory behavior GO:0007635 1 0.013
apoptotic process involved in development GO:1902742 2 0.013
regulation of nucleotide catabolic process GO:0030811 2 0.013
mitochondrion organization GO:0007005 4 0.013
cytokinesis GO:0000910 3 0.013
adult behavior GO:0030534 2 0.013
guanosine containing compound catabolic process GO:1901069 2 0.013
cellular component disassembly GO:0022411 1 0.013
programmed cell death GO:0012501 119 0.013
protein stabilization GO:0050821 2 0.013
cell migration involved in gastrulation GO:0042074 79 0.013
positive regulation of cellular component biogenesis GO:0044089 3 0.013
Human
positive regulation of cytoskeleton organization GO:0051495 3 0.013
Human
regulation of meiotic cell cycle GO:0051445 1 0.013
cilium assembly GO:0042384 58 0.013
alpha amino acid metabolic process GO:1901605 3 0.013
positive regulation of nucleotide catabolic process GO:0030813 1 0.013
proteasomal protein catabolic process GO:0010498 2 0.013
developmental growth GO:0048589 166 0.013
production of molecular mediator of immune response GO:0002440 2 0.013
locomotor rhythm GO:0045475 3 0.013
regulation of purine nucleotide catabolic process GO:0033121 2 0.013
cellular protein metabolic process GO:0044267 129 0.013
cell substrate adhesion GO:0031589 4 0.013
regulation of developmental process GO:0050793 247 0.013
cellular component assembly involved in morphogenesis GO:0010927 107 0.013
positive regulation of protein complex assembly GO:0031334 2 0.012
Human
convergent extension involved in gastrulation GO:0060027 71 0.012
development of primary female sexual characteristics GO:0046545 4 0.012
dorsal ventral pattern formation GO:0009953 125 0.012
convergent extension GO:0060026 118 0.012
nucleic acid templated transcription GO:0097659 181 0.012
Human
canonical wnt signaling pathway GO:0060070 48 0.012
positive regulation of nucleoside metabolic process GO:0045979 1 0.012
response to carbohydrate GO:0009743 3 0.012
cell morphogenesis involved in differentiation GO:0000904 195 0.012
Fly
negative regulation of response to stimulus GO:0048585 104 0.012
Fly
lamellipodium assembly GO:0030032 1 0.012
Mouse
cellular response to chemical stimulus GO:0070887 157 0.012
Fly
regulation of cell activation GO:0050865 1 0.012
Human
phagocytosis engulfment GO:0006911 1 0.012
negative regulation of defense response GO:0031348 2 0.012
somite development GO:0061053 96 0.012
pathway restricted smad protein phosphorylation GO:0060389 1 0.012
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.012
Human
regulation of protein targeting GO:1903533 2 0.012
regulation of blood vessel size GO:0050880 2 0.012
insulin like growth factor receptor signaling pathway GO:0048009 4 0.012
embryonic organ morphogenesis GO:0048562 274 0.011
atp catabolic process GO:0006200 4 0.011
negative regulation of protein localization to nucleus GO:1900181 2 0.011
lamellipodium organization GO:0097581 1 0.011
Mouse
positive regulation of dna metabolic process GO:0051054 1 0.011
negative regulation of signaling GO:0023057 96 0.011
Fly
meiotic cell cycle process GO:1903046 3 0.011
cellular component assembly GO:0022607 170 0.011
Human Mouse
angiogenesis GO:0001525 158 0.011
immune system development GO:0002520 191 0.011
positive regulation of apoptotic signaling pathway GO:2001235 1 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
developmental programmed cell death GO:0010623 4 0.011
embryonic heart tube morphogenesis GO:0003143 108 0.011
hematopoietic or lymphoid organ development GO:0048534 191 0.011
brain development GO:0007420 293 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.011
muscle organ development GO:0007517 101 0.011
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.011
synaptic target recognition GO:0008039 1 0.011
membrane invagination GO:0010324 1 0.011
mesenchyme development GO:0060485 127 0.011
head development GO:0060322 303 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.011
muscle cell migration GO:0014812 4 0.011
chordate embryonic development GO:0043009 271 0.011
regulation of tube size GO:0035150 2 0.011
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.011
negative regulation of signal transduction GO:0009968 94 0.011
Fly
protein localization to plasma membrane GO:0072659 1 0.011
cellular response to stress GO:0033554 62 0.011
hormone transport GO:0009914 2 0.011
negative regulation of protein kinase activity GO:0006469 4 0.011
regulation of inflammatory response GO:0050727 2 0.011
generation of neurons GO:0048699 385 0.011
Fly
secondary metabolic process GO:0019748 3 0.011
centrosome organization GO:0051297 1 0.011
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.011
Human
positive regulation of cellular process GO:0048522 201 0.011
Human
cellular response to extracellular stimulus GO:0031668 2 0.010
positive regulation of jun kinase activity GO:0043507 2 0.010
apoptotic process involved in morphogenesis GO:0060561 2 0.010
negative regulation of biosynthetic process GO:0009890 55 0.010
cellular response to external stimulus GO:0071496 2 0.010
regulation of epithelial cell proliferation GO:0050678 3 0.010
somatic muscle development GO:0007525 4 0.010
multi organism cellular process GO:0044764 2 0.010
positive regulation of response to stimulus GO:0048584 80 0.010
regulation of wnt signaling pathway GO:0030111 53 0.010
camera type eye development GO:0043010 222 0.010
nuclear migration GO:0007097 3 0.010
positive regulation of cellular biosynthetic process GO:0031328 68 0.010
Human
response to vitamin GO:0033273 3 0.010
regulation of canonical wnt signaling pathway GO:0060828 34 0.010
positive regulation of signaling GO:0023056 56 0.010

nck2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.030
nervous system disease DOID:863 0 0.023
disease of metabolism DOID:0014667 0 0.014
inherited metabolic disorder DOID:655 0 0.014
cardiovascular system disease DOID:1287 0 0.011