Danio rerio

0 known processes

parp6a

poly (ADP-ribose) polymerase family, member 6a

(Aliases: zgc:92798)

parp6a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.073
maintenance of location GO:0051235 4 0.047
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.040
cellular protein catabolic process GO:0044257 4 0.040
positive regulation of transport GO:0051050 2 0.039
ubiquitin dependent protein catabolic process GO:0006511 3 0.037
multicellular organism growth GO:0035264 4 0.036
response to chemical GO:0042221 320 0.035
aging GO:0007568 2 0.035
lipid storage GO:0019915 1 0.033
signal transduction GO:0007165 455 0.033
phagocytosis GO:0006909 3 0.033
cellular amine metabolic process GO:0044106 2 0.032
modification dependent macromolecule catabolic process GO:0043632 3 0.031
meiotic nuclear division GO:0007126 4 0.030
amine metabolic process GO:0009308 2 0.030
regulation of metabolic process GO:0019222 359 0.030
regulation of establishment of protein localization GO:0070201 4 0.030
cellular macromolecule metabolic process GO:0044260 391 0.029
positive regulation of catabolic process GO:0009896 4 0.029
response to drug GO:0042493 3 0.029
cytokinesis GO:0000910 3 0.029
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.028
regulation of multicellular organism growth GO:0040014 4 0.028
nitrogen compound metabolic process GO:0006807 319 0.027
modification dependent protein catabolic process GO:0019941 3 0.027
organic substance biosynthetic process GO:1901576 289 0.026
cell surface receptor signaling pathway GO:0007166 325 0.026
cellular amino acid metabolic process GO:0006520 7 0.026
establishment of protein localization to organelle GO:0072594 4 0.026
regulation of cellular amine metabolic process GO:0033238 0 0.026
cellular nitrogen compound metabolic process GO:0034641 290 0.026
positive regulation of cellular catabolic process GO:0031331 3 0.025
proteasomal protein catabolic process GO:0010498 2 0.025
regulation of cytokine production GO:0001817 3 0.025
positive regulation of cellular component biogenesis GO:0044089 3 0.025
protein import GO:0017038 3 0.025
regulation of protein transport GO:0051223 3 0.025
positive regulation of secretion by cell GO:1903532 1 0.024
regulation of cellular amino acid metabolic process GO:0006521 0 0.024
regulation of nitrogen compound metabolic process GO:0051171 251 0.024
positive regulation of cell cycle GO:0045787 3 0.024
cellular aromatic compound metabolic process GO:0006725 295 0.024
heterocycle metabolic process GO:0046483 290 0.024
cellular biosynthetic process GO:0044249 286 0.024
regulation of meiotic cell cycle GO:0051445 1 0.023
nuclear transport GO:0051169 4 0.023
protein localization to nucleus GO:0034504 3 0.023
negative regulation of protein phosphorylation GO:0001933 4 0.023
mitochondrion organization GO:0007005 4 0.023
positive regulation of cytokine production GO:0001819 2 0.023
gene expression GO:0010467 252 0.023
cellular ketone metabolic process GO:0042180 11 0.023
organic cyclic compound metabolic process GO:1901360 301 0.023
regulation of macromolecule metabolic process GO:0060255 317 0.023
rna metabolic process GO:0016070 219 0.022
meiotic cell cycle process GO:1903046 3 0.022
organonitrogen compound metabolic process GO:1901564 74 0.022
response to stress GO:0006950 263 0.021
cellular response to external stimulus GO:0071496 2 0.021
small molecule metabolic process GO:0044281 77 0.021
regionalization GO:0003002 274 0.021
negative regulation of biological process GO:0048519 304 0.021
autophagy GO:0006914 4 0.020
protein localization to plasma membrane GO:0072659 1 0.020
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.020
sensory organ development GO:0007423 393 0.020
regulation of response to stimulus GO:0048583 269 0.020
nucleocytoplasmic transport GO:0006913 4 0.020
protein acylation GO:0043543 3 0.020
stem cell maintenance GO:0019827 4 0.020
regulation of binding GO:0051098 3 0.020
biosynthetic process GO:0009058 294 0.020
gtp metabolic process GO:0046039 4 0.020
regulation of cellular ketone metabolic process GO:0010565 7 0.020
guanosine containing compound metabolic process GO:1901068 4 0.020
regulation of developmental process GO:0050793 247 0.020
single organism metabolic process GO:0044710 217 0.019
oxoacid metabolic process GO:0043436 31 0.019
carboxylic acid metabolic process GO:0019752 22 0.019
internal protein amino acid acetylation GO:0006475 2 0.019
regulation of cytoplasmic transport GO:1903649 4 0.019
peptidyl lysine acetylation GO:0018394 2 0.019
nucleic acid metabolic process GO:0090304 244 0.019
protein metabolic process GO:0019538 183 0.019
positive regulation of cellular amine metabolic process GO:0033240 0 0.019
protein acetylation GO:0006473 2 0.019
organic acid metabolic process GO:0006082 31 0.019
regulation of protein catabolic process GO:0042176 1 0.019
cellular nitrogen compound biosynthetic process GO:0044271 218 0.019
heterocycle biosynthetic process GO:0018130 215 0.019
adult behavior GO:0030534 2 0.018
regulation of cellular biosynthetic process GO:0031326 245 0.018
macromolecule biosynthetic process GO:0009059 227 0.018
cellular component movement GO:0006928 335 0.018
cell migration GO:0016477 237 0.018
nucleobase containing compound metabolic process GO:0006139 274 0.018
negative regulation of cellular process GO:0048523 283 0.018
regulation of protein complex assembly GO:0043254 3 0.018
regulation of cellular metabolic process GO:0031323 320 0.018
erk1 and erk2 cascade GO:0070371 4 0.018
endosomal transport GO:0016197 2 0.018
tissue remodeling GO:0048771 4 0.018
regulation of reproductive process GO:2000241 4 0.018
embryonic organ development GO:0048568 381 0.018
cytoskeleton dependent cytokinesis GO:0061640 3 0.018
guanosine containing compound catabolic process GO:1901069 2 0.017
nuclear import GO:0051170 3 0.017
protein secretion GO:0009306 1 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.017
golgi vesicle transport GO:0048193 3 0.017
single organism nuclear import GO:1902593 3 0.017
negative regulation of protein kinase activity GO:0006469 4 0.017
nucleic acid templated transcription GO:0097659 181 0.017
gtp catabolic process GO:0006184 2 0.017
regulation of cell activation GO:0050865 1 0.017
cellular response to extracellular stimulus GO:0031668 2 0.017
transcription dna templated GO:0006351 181 0.017
regulation of multicellular organismal process GO:0051239 277 0.017
regulation of signaling GO:0023051 235 0.017
locomotion GO:0040011 313 0.017
positive regulation of secretion GO:0051047 1 0.017
stem cell proliferation GO:0072089 4 0.017
tube morphogenesis GO:0035239 349 0.017
establishment of protein localization to plasma membrane GO:0090002 1 0.017
regulation of gene expression GO:0010468 265 0.017
cellular response to chemical stimulus GO:0070887 157 0.017
regulation of biological quality GO:0065008 263 0.017
organic cyclic compound biosynthetic process GO:1901362 223 0.016
embryo development ending in birth or egg hatching GO:0009792 271 0.016
central nervous system development GO:0007417 387 0.016
interspecies interaction between organisms GO:0044419 4 0.016
female sex differentiation GO:0046660 4 0.016
regulation of primary metabolic process GO:0080090 311 0.016
internal peptidyl lysine acetylation GO:0018393 2 0.016
compound eye development GO:0048749 2 0.016
phagocytosis engulfment GO:0006911 1 0.016
aromatic compound biosynthetic process GO:0019438 217 0.016
morphogenesis of an epithelium GO:0002009 333 0.016
cellular macromolecule biosynthetic process GO:0034645 224 0.016
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.016
regulation of mrna processing GO:0050684 3 0.016
regulation of transcription dna templated GO:0006355 213 0.016
hemopoiesis GO:0030097 183 0.016
peptidyl serine modification GO:0018209 2 0.015
regulation of macromolecule biosynthetic process GO:0010556 225 0.015
protein stabilization GO:0050821 2 0.015
regulation of biosynthetic process GO:0009889 250 0.015
regulation of blood pressure GO:0008217 1 0.015
cellular component disassembly GO:0022411 1 0.015
extrinsic apoptotic signaling pathway GO:0097191 3 0.015
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.015
regulation of inflammatory response GO:0050727 2 0.015
protein targeting to nucleus GO:0044744 3 0.015
regulation of intracellular protein transport GO:0033157 3 0.015
immune system development GO:0002520 191 0.015
g1 s transition of mitotic cell cycle GO:0000082 1 0.015
camera type eye development GO:0043010 222 0.015
regulation of nucleocytoplasmic transport GO:0046822 2 0.015
cellular component biogenesis GO:0044085 178 0.015
regulation of signal transduction GO:0009966 225 0.015
regulation of stem cell proliferation GO:0072091 2 0.015
spermatid development GO:0007286 2 0.015
centrosome organization GO:0051297 1 0.015
chordate embryonic development GO:0043009 271 0.015
locomotor rhythm GO:0045475 3 0.015
system process GO:0003008 185 0.015
digestive tract development GO:0048565 265 0.015
immune system process GO:0002376 241 0.015
neuron differentiation GO:0030182 353 0.015
organelle fusion GO:0048284 3 0.015
single organism localization GO:1902578 225 0.015
wnt signaling pathway GO:0016055 80 0.014
cellular response to nutrient levels GO:0031669 2 0.014
blood vessel development GO:0001568 246 0.014
nucleobase containing compound biosynthetic process GO:0034654 205 0.014
protein modification process GO:0036211 100 0.014
generation of neurons GO:0048699 385 0.014
developmental programmed cell death GO:0010623 4 0.014
regulation of purine nucleotide catabolic process GO:0033121 2 0.014
membrane invagination GO:0010324 1 0.014
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.014
cellular response to biotic stimulus GO:0071216 3 0.014
cellular response to lipopolysaccharide GO:0071222 3 0.014
cellular response to molecule of bacterial origin GO:0071219 3 0.014
anterior posterior pattern specification GO:0009952 152 0.014
negative regulation of kinase activity GO:0033673 4 0.014
protein import into nucleus GO:0006606 3 0.014
establishment of localization GO:0051234 244 0.014
cell cycle g1 s phase transition GO:0044843 1 0.014
regulation of cell communication GO:0010646 232 0.014
regulation of protein localization to nucleus GO:1900180 2 0.014
regulation of cell shape GO:0008360 1 0.014
secondary metabolic process GO:0019748 3 0.014
regulation of nucleic acid templated transcription GO:1903506 213 0.014
organelle organization GO:0006996 227 0.014
membrane fusion GO:0061025 2 0.014
regulation of protein targeting GO:1903533 2 0.014
spermatid differentiation GO:0048515 2 0.014
cytoplasm organization GO:0007028 4 0.013
determination of bilateral symmetry GO:0009855 204 0.013
regulation of circadian rhythm GO:0042752 4 0.013
vasculature development GO:0001944 278 0.013
atp catabolic process GO:0006200 4 0.013
stem cell division GO:0017145 1 0.013
regulation of autophagy GO:0010506 3 0.013
response to nutrient GO:0007584 3 0.013
regulation of rna biosynthetic process GO:2001141 213 0.013
protein polymerization GO:0051258 4 0.013
positive regulation of cytoskeleton organization GO:0051495 3 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.013
macromolecule modification GO:0043412 111 0.013
specification of symmetry GO:0009799 204 0.013
cell morphogenesis GO:0000902 289 0.013
growth GO:0040007 174 0.013
regulation of rna metabolic process GO:0051252 224 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.013
cellular component morphogenesis GO:0032989 336 0.013
production of molecular mediator of immune response GO:0002440 2 0.013
regulation of synapse assembly GO:0051963 3 0.013
regulation of protein ubiquitination GO:0031396 3 0.013
development of primary female sexual characteristics GO:0046545 4 0.013
single organism membrane fusion GO:0044801 2 0.013
response to external stimulus GO:0009605 264 0.013
cellular component assembly GO:0022607 170 0.013
exocytosis GO:0006887 1 0.013
cellular protein modification process GO:0006464 100 0.013
negative regulation of mapk cascade GO:0043409 4 0.013
cellular carbohydrate metabolic process GO:0044262 4 0.013
nucleoside monophosphate catabolic process GO:0009125 4 0.013
rna biosynthetic process GO:0032774 181 0.013
microtubule organizing center organization GO:0031023 1 0.013
cellular respiration GO:0045333 3 0.013
regulation of protein import into nucleus GO:0042306 2 0.013
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.013
transport GO:0006810 220 0.013
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.013
germ line stem cell maintenance GO:0030718 2 0.013
brain development GO:0007420 293 0.013
head development GO:0060322 303 0.012
regulation of nucleoside metabolic process GO:0009118 2 0.012
protein polyubiquitination GO:0000209 4 0.012
neuron development GO:0048666 262 0.012
i kappab kinase nf kappab signaling GO:0007249 4 0.012
positive regulation of apoptotic signaling pathway GO:2001235 1 0.012
gastrulation GO:0007369 208 0.012
developmental growth GO:0048589 166 0.012
translational initiation GO:0006413 3 0.012
digestive tract morphogenesis GO:0048546 231 0.012
rna localization GO:0006403 4 0.012
neuroblast proliferation GO:0007405 2 0.012
sequestering of calcium ion GO:0051208 3 0.012
adherens junction organization GO:0034332 4 0.012
hormone secretion GO:0046879 2 0.012
cellular response to starvation GO:0009267 1 0.012
cell motility GO:0048870 244 0.012
eye development GO:0001654 277 0.012
transcription from rna polymerase ii promoter GO:0006366 80 0.012
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.012
positive regulation of cell adhesion GO:0045785 1 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.012
protein homooligomerization GO:0051260 3 0.012
response to monosaccharide GO:0034284 3 0.012
digestive system development GO:0055123 289 0.012
protein heterooligomerization GO:0051291 1 0.012
female gonad development GO:0008585 4 0.012
positive regulation of immune effector process GO:0002699 3 0.012
regulation of neural precursor cell proliferation GO:2000177 3 0.012
cognition GO:0050890 1 0.012
regulation of organelle assembly GO:1902115 4 0.012
cellular response to organic substance GO:0071310 105 0.012
death GO:0016265 121 0.012
regulation of mrna splicing via spliceosome GO:0048024 3 0.012
multi organism cellular process GO:0044764 2 0.012
positive regulation of cellular process GO:0048522 201 0.011
actin filament polymerization GO:0030041 2 0.011
hormone transport GO:0009914 2 0.011
embryonic organ morphogenesis GO:0048562 274 0.011
mononuclear cell proliferation GO:0032943 1 0.011
protein dephosphorylation GO:0006470 3 0.011
mitotic cell cycle embryonic GO:0045448 2 0.011
mitotic cytokinesis GO:0000281 3 0.011
sequestering of metal ion GO:0051238 3 0.011
cytokinetic process GO:0032506 2 0.011
synaptic growth at neuromuscular junction GO:0051124 2 0.011
negative regulation of signal transduction GO:0009968 94 0.011
regulation of nucleotide catabolic process GO:0030811 2 0.011
macromolecular complex disassembly GO:0032984 1 0.011
response to hexose GO:0009746 3 0.011
olfactory lobe development GO:0021988 4 0.011
positive regulation of cell division GO:0051781 2 0.011
regulation of synaptic plasticity GO:0048167 1 0.011
regulation of stem cell differentiation GO:2000736 4 0.011
cell projection organization GO:0030030 284 0.011
protein complex disassembly GO:0043241 1 0.011
single organism organelle organization GO:1902589 199 0.011
cell part morphogenesis GO:0032990 246 0.011
regulation of erk1 and erk2 cascade GO:0070372 4 0.011
negative regulation of catabolic process GO:0009895 3 0.011
purine nucleoside monophosphate catabolic process GO:0009128 4 0.011
angiogenesis GO:0001525 158 0.011
leukocyte proliferation GO:0070661 1 0.011
cellular response to light stimulus GO:0071482 4 0.011
response to uv GO:0009411 3 0.011
positive regulation of gtpase activity GO:0043547 1 0.011
regulation of cellular protein catabolic process GO:1903362 1 0.011
response to topologically incorrect protein GO:0035966 2 0.011
meiotic chromosome segregation GO:0045132 3 0.011
phosphorus metabolic process GO:0006793 109 0.011
synaptic vesicle localization GO:0097479 1 0.011
regulation of gtpase activity GO:0043087 2 0.011
regulation of production of molecular mediator of immune response GO:0002700 1 0.011
heart development GO:0007507 313 0.011
ribonucleoside monophosphate catabolic process GO:0009158 4 0.011
lateral inhibition GO:0046331 1 0.011
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.011
cell substrate adhesion GO:0031589 4 0.011
negative regulation of signaling GO:0023057 96 0.011
positive regulation of chromatin modification GO:1903310 1 0.011
cell death GO:0008219 121 0.011
positive regulation of dna metabolic process GO:0051054 1 0.011
single fertilization GO:0007338 3 0.011
lymphocyte proliferation GO:0046651 1 0.011
cellular amide metabolic process GO:0043603 4 0.011
segmentation GO:0035282 97 0.011
hematopoietic or lymphoid organ development GO:0048534 191 0.011
positive regulation of nucleotide catabolic process GO:0030813 1 0.011
carbohydrate homeostasis GO:0033500 1 0.011
positive regulation of notch signaling pathway GO:0045747 3 0.011
cellular protein metabolic process GO:0044267 129 0.011
negative regulation of response to stimulus GO:0048585 104 0.010
cellular response to radiation GO:0071478 4 0.010
negative regulation of sequestering of calcium ion GO:0051283 4 0.010
sensory organ morphogenesis GO:0090596 200 0.010
small molecule catabolic process GO:0044282 3 0.010
response to organic substance GO:0010033 153 0.010
chemosensory behavior GO:0007635 1 0.010
regulation of multicellular organismal development GO:2000026 223 0.010
actin polymerization or depolymerization GO:0008154 2 0.010
glucose homeostasis GO:0042593 1 0.010
cell projection morphogenesis GO:0048858 244 0.010
programmed cell death GO:0012501 119 0.010
regulation of jak stat cascade GO:0046425 3 0.010
synaptic vesicle transport GO:0048489 1 0.010
negative regulation of defense response GO:0031348 2 0.010
apoptotic process GO:0006915 116 0.010
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.010
peptide transport GO:0015833 1 0.010
blood vessel morphogenesis GO:0048514 216 0.010
regulation of dna replication GO:0006275 3 0.010
negative regulation of multi organism process GO:0043901 3 0.010
positive regulation of reproductive process GO:2000243 2 0.010
negative regulation of secretion GO:0051048 2 0.010
determination of left right symmetry GO:0007368 179 0.010
skeletal system development GO:0001501 181 0.010
response to carbohydrate GO:0009743 3 0.010
lamellipodium organization GO:0097581 1 0.010
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.010
response to hydrogen peroxide GO:0042542 3 0.010
phosphate containing compound metabolic process GO:0006796 108 0.010
regulation of tube size GO:0035150 2 0.010

parp6a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.039
nervous system disease DOID:863 0 0.019
musculoskeletal system disease DOID:17 0 0.014
disease of metabolism DOID:0014667 0 0.013
disease of cellular proliferation DOID:14566 0 0.012
cancer DOID:162 0 0.012