Danio rerio

28 known processes

cc2d2a

coiled-coil and C2 domain containing 2A

(Aliases: wu:fc03c12,fc03c12)

cc2d2a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
microtubule based movement GO:0007018 33 1.000
nonmotile primary cilium assembly GO:0035058 2 0.990
cilium organization GO:0044782 71 0.984
cilium assembly GO:0042384 58 0.982
cilium morphogenesis GO:0060271 85 0.953
retina homeostasis GO:0001895 12 0.932
specification of symmetry GO:0009799 204 0.928
cell projection assembly GO:0030031 64 0.895
tissue homeostasis GO:0001894 25 0.872
digestive tract development GO:0048565 265 0.867
organelle organization GO:0006996 227 0.859
embryonic heart tube development GO:0035050 133 0.837
cilium movement GO:0003341 26 0.832
multicellular organismal homeostasis GO:0048871 29 0.822
tube morphogenesis GO:0035239 349 0.816
cell projection organization GO:0030030 284 0.801
embryonic organ morphogenesis GO:0048562 274 0.796
cell morphogenesis GO:0000902 289 0.769
neuron development GO:0048666 262 0.743
spermatid differentiation GO:0048515 2 0.739
cellular pigmentation GO:0033059 30 0.732
axoneme assembly GO:0035082 9 0.706
convergent extension GO:0060026 118 0.675
eye development GO:0001654 277 0.670
cellular component assembly involved in morphogenesis GO:0010927 107 0.654
determination of left right symmetry GO:0007368 179 0.626
generation of neurons GO:0048699 385 0.601
sensory organ development GO:0007423 393 0.595
cell projection morphogenesis GO:0048858 244 0.594
photoreceptor cell differentiation GO:0046530 55 0.582
photoreceptor cell development GO:0042461 40 0.579
digestive system development GO:0055123 289 0.554
determination of bilateral symmetry GO:0009855 204 0.539
anatomical structure homeostasis GO:0060249 36 0.535
single organism organelle organization GO:1902589 199 0.534
sensory organ morphogenesis GO:0090596 200 0.520
photoreceptor cell maintenance GO:0045494 11 0.510
single organism localization GO:1902578 225 0.501
cellular component biogenesis GO:0044085 178 0.497
establishment of melanosome localization GO:0032401 19 0.480
smoothened signaling pathway GO:0007224 30 0.459
eye morphogenesis GO:0048592 144 0.458
cellular component assembly GO:0022607 170 0.450
heart looping GO:0001947 94 0.438
embryonic organ development GO:0048568 381 0.438
organelle assembly GO:0070925 110 0.437
cellular component movement GO:0006928 335 0.425
signal transduction GO:0007165 455 0.422
microtubule based process GO:0007017 60 0.402
regulation of smoothened signaling pathway GO:0008589 18 0.400
central nervous system development GO:0007417 387 0.398
eye photoreceptor cell differentiation GO:0001754 45 0.381
embryonic heart tube morphogenesis GO:0003143 108 0.358
morphogenesis of an epithelium GO:0002009 333 0.336
positive regulation of biological process GO:0048518 253 0.329
sensory perception of mechanical stimulus GO:0050954 16 0.317
cytokinesis GO:0000910 3 0.308
heart morphogenesis GO:0003007 156 0.306
determination of heart left right asymmetry GO:0061371 117 0.291
brain development GO:0007420 293 0.288
ventral spinal cord development GO:0021517 35 0.282
neuron differentiation GO:0030182 353 0.279
primary neural tube formation GO:0014020 1 0.272
gastrulation GO:0007369 208 0.259
neural retina development GO:0003407 49 0.256
multicellular organismal reproductive process GO:0048609 35 0.242
detection of stimulus involved in sensory perception GO:0050906 21 0.238
ear development GO:0043583 127 0.232
meiotic nuclear division GO:0007126 4 0.228
inner ear development GO:0048839 126 0.206
neuron projection development GO:0031175 180 0.196
establishment of vesicle localization GO:0051650 24 0.195
single organism transport GO:0044765 206 0.194
central nervous system neuron differentiation GO:0021953 74 0.187
microtubule based transport GO:0010970 10 0.184
gene expression GO:0010467 252 0.184
notch signaling pathway GO:0007219 35 0.175
organelle localization GO:0051640 49 0.175
localization of cell GO:0051674 244 0.174
cell motility GO:0048870 244 0.172
adult behavior GO:0030534 2 0.168
mechanoreceptor differentiation GO:0042490 37 0.167
locomotion GO:0040011 313 0.167
digestive tract morphogenesis GO:0048546 231 0.164
epithelial cilium movement GO:0003351 15 0.163
cell differentiation in spinal cord GO:0021515 40 0.161
cell part morphogenesis GO:0032990 246 0.161
cellular component morphogenesis GO:0032989 336 0.160
regulation of biological quality GO:0065008 263 0.157
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.150
spermatid development GO:0007286 2 0.145
positive regulation of epithelial cell differentiation GO:0030858 2 0.142
larval development GO:0002164 2 0.140
epithelial cilium movement involved in determination of left right asymmetry GO:0060287 8 0.140
camera type eye development GO:0043010 222 0.136
retina development in camera type eye GO:0060041 146 0.134
epithelial tube formation GO:0072175 19 0.132
positive regulation of cellular process GO:0048522 201 0.130
inner ear receptor cell differentiation GO:0060113 29 0.126
chemosensory behavior GO:0007635 1 0.121
cilium movement involved in cell motility GO:0060294 3 0.120
mitotic cell cycle GO:0000278 64 0.119
vesicle localization GO:0051648 27 0.117
cytoskeleton organization GO:0007010 96 0.116
establishment of organelle localization GO:0051656 45 0.116
tube closure GO:0060606 1 0.112
epithelial tube morphogenesis GO:0060562 148 0.111
pronephros development GO:0048793 69 0.108
neurological system process GO:0050877 62 0.105
establishment of localization GO:0051234 244 0.103
convergent extension involved in gastrulation GO:0060027 71 0.099
tube formation GO:0035148 25 0.097
homeostatic process GO:0042592 142 0.097
eye photoreceptor cell development GO:0042462 30 0.096
epidermis development GO:0008544 48 0.093
protein metabolic process GO:0019538 183 0.093
system process GO:0003008 185 0.092
regulation of signaling GO:0023051 235 0.091
regulation of epithelial cell proliferation GO:0050678 3 0.091
embryonic epithelial tube formation GO:0001838 17 0.087
floor plate morphogenesis GO:0033505 12 0.084
taxis GO:0042330 109 0.080
positive regulation of smoothened signaling pathway GO:0045880 5 0.079
kidney development GO:0001822 92 0.079
forebrain development GO:0030900 96 0.078
cell surface receptor signaling pathway GO:0007166 325 0.078
retina morphogenesis in camera type eye GO:0060042 79 0.077
cellular macromolecule metabolic process GO:0044260 391 0.077
inner ear receptor cell development GO:0060119 20 0.077
photoreceptor cell outer segment organization GO:0035845 9 0.075
regulation of gene expression GO:0010468 265 0.075
mitotic cell cycle process GO:1903047 48 0.071
negative regulation of biological process GO:0048519 304 0.071
cellular nitrogen compound biosynthetic process GO:0044271 218 0.071
intraciliary transport GO:0042073 7 0.070
response to external stimulus GO:0009605 264 0.070
regulation of macromolecule metabolic process GO:0060255 317 0.068
renal system development GO:0072001 94 0.068
convergent extension involved in organogenesis GO:0060029 10 0.067
meiotic cell cycle process GO:1903046 3 0.066
regulation of cell projection assembly GO:0060491 4 0.066
multi organism process GO:0051704 134 0.065
regulation of cell communication GO:0010646 232 0.065
single organism cellular localization GO:1902580 46 0.063
behavior GO:0007610 74 0.063
detection of mechanical stimulus GO:0050982 11 0.063
transport GO:0006810 220 0.061
gamete generation GO:0007276 33 0.060
chondrocyte intercalation involved in growth plate cartilage morphogenesis GO:0003428 1 0.060
regulation of metabolic process GO:0019222 359 0.059
cell cycle GO:0007049 93 0.059
establishment of localization in cell GO:0051649 77 0.059
regulation of microtubule based movement GO:0060632 3 0.059
heart development GO:0007507 313 0.058
regulation of cellular component organization GO:0051128 86 0.058
reproductive process GO:0022414 40 0.057
macromolecular complex subunit organization GO:0043933 74 0.056
embryo development ending in birth or egg hatching GO:0009792 271 0.054
detection of stimulus GO:0051606 29 0.054
multicellular organism growth GO:0035264 4 0.053
spinal cord development GO:0021510 46 0.052
microtubule cytoskeleton organization GO:0000226 33 0.052
response to mechanical stimulus GO:0009612 24 0.050
camera type eye morphogenesis GO:0048593 108 0.050
detection of external stimulus GO:0009581 24 0.049
inner ear receptor stereocilium organization GO:0060122 8 0.048
intracellular transport GO:0046907 32 0.047
positive regulation of signal transduction GO:0009967 56 0.047
brain morphogenesis GO:0048854 18 0.047
regulation of cell morphogenesis GO:0022604 42 0.046
neuromuscular synaptic transmission GO:0007274 2 0.046
regulation of organelle assembly GO:1902115 4 0.045
multicellular organismal signaling GO:0035637 22 0.044
synaptic transmission GO:0007268 35 0.044
cellular localization GO:0051641 97 0.043
transcription dna templated GO:0006351 181 0.042
single organism behavior GO:0044708 24 0.041
sensory perception of sound GO:0007605 9 0.041
pigment granule localization GO:0051875 25 0.041
positive regulation of cellular component biogenesis GO:0044089 3 0.040
microtubule bundle formation GO:0001578 9 0.039
auditory receptor cell differentiation GO:0042491 15 0.039
camera type eye photoreceptor cell differentiation GO:0060219 19 0.039
inner ear morphogenesis GO:0042472 63 0.039
atp catabolic process GO:0006200 4 0.039
spinal cord motor neuron differentiation GO:0021522 26 0.039
retina layer formation GO:0010842 24 0.038
myotube differentiation GO:0014902 45 0.038
positive regulation of catabolic process GO:0009896 4 0.038
protein complex subunit organization GO:0071822 46 0.038
cellular response to organic substance GO:0071310 105 0.037
negative regulation of response to stimulus GO:0048585 104 0.037
appendage development GO:0048736 80 0.037
endocardium morphogenesis GO:0003160 4 0.036
regulation of purine nucleotide catabolic process GO:0033121 2 0.036
response to chemical GO:0042221 320 0.036
head development GO:0060322 303 0.035
regulation of multicellular organismal process GO:0051239 277 0.035
sensory perception of chemical stimulus GO:0007606 3 0.034
circulatory system process GO:0003013 87 0.034
cellular aromatic compound metabolic process GO:0006725 295 0.034
enzyme linked receptor protein signaling pathway GO:0007167 106 0.033
protein localization GO:0008104 40 0.033
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.032
neural tube development GO:0021915 62 0.032
regulation of developmental process GO:0050793 247 0.032
regulation of cilium assembly GO:1902017 2 0.032
response to food GO:0032094 1 0.031
neural tube formation GO:0001841 16 0.030
photoreceptor cell fate specification GO:0043704 1 0.030
chordate embryonic development GO:0043009 271 0.030
pigmentation GO:0043473 85 0.030
swimming behavior GO:0036269 8 0.029
ameboidal type cell migration GO:0001667 143 0.029
distal tubule development GO:0072017 1 0.029
motor neuron axon guidance GO:0008045 23 0.029
cell migration involved in gastrulation GO:0042074 79 0.028
dorsal ventral pattern formation GO:0009953 125 0.028
single organism reproductive process GO:0044702 40 0.028
muscle cell differentiation GO:0042692 139 0.028
biosynthetic process GO:0009058 294 0.028
detection of mechanical stimulus involved in sensory perception GO:0050974 11 0.028
nucleic acid templated transcription GO:0097659 181 0.027
negative regulation of histone methylation GO:0031061 1 0.027
regulation of signal transduction GO:0009966 225 0.027
locomotory behavior GO:0007626 34 0.026
rna metabolic process GO:0016070 219 0.026
growth GO:0040007 174 0.026
developmental maturation GO:0021700 34 0.026
cell cycle process GO:0022402 53 0.026
embryonic limb morphogenesis GO:0030326 2 0.026
somitogenesis GO:0001756 87 0.025
negative regulation of epithelial cell proliferation GO:0050680 1 0.025
pigment granule transport GO:0051904 19 0.024
nucleic acid metabolic process GO:0090304 244 0.024
oocyte anterior posterior axis specification GO:0007314 4 0.024
regulation of neural retina development GO:0061074 2 0.024
membrane repolarization GO:0086009 2 0.024
determination of intestine left right asymmetry GO:0071908 2 0.024
determination of digestive tract left right asymmetry GO:0071907 10 0.024
regulation of membrane potential GO:0042391 23 0.024
cellular nitrogen compound metabolic process GO:0034641 290 0.024
establishment of pigment granule localization GO:0051905 22 0.024
macromolecular complex assembly GO:0065003 35 0.024
regionalization GO:0003002 274 0.023
developmental process involved in reproduction GO:0003006 27 0.023
urogenital system development GO:0001655 97 0.023
pigment granule aggregation in cell center GO:0051877 8 0.022
regulation of synapse organization GO:0050807 3 0.022
embryonic viscerocranium morphogenesis GO:0048703 52 0.022
male gamete generation GO:0048232 7 0.022
forebrain cell migration GO:0021885 1 0.022
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000462 1 0.022
regulation of cell projection organization GO:0031344 44 0.022
nephron epithelium development GO:0072009 16 0.022
developmental programmed cell death GO:0010623 4 0.021
post embryonic organ morphogenesis GO:0048563 1 0.021
membrane invagination GO:0010324 1 0.021
skeletal system development GO:0001501 181 0.021
protein maturation GO:0051604 12 0.021
regulation of ion transmembrane transporter activity GO:0032412 2 0.021
developmental growth GO:0048589 166 0.020
heterocycle metabolic process GO:0046483 290 0.020
hair cell differentiation GO:0035315 32 0.020
regulation of cellular component movement GO:0051270 55 0.020
gtp metabolic process GO:0046039 4 0.020
growth plate cartilage morphogenesis GO:0003422 1 0.019
regulation of neurogenesis GO:0050767 87 0.019
nitrogen compound metabolic process GO:0006807 319 0.019
regulation of organelle organization GO:0033043 29 0.019
blood circulation GO:0008015 87 0.018
cardiogenic plate morphogenesis GO:0003142 1 0.018
olfactory lobe development GO:0021988 4 0.018
regulation of localization GO:0032879 104 0.018
regulation of transporter activity GO:0032409 2 0.018
kupffer s vesicle development GO:0070121 50 0.018
sexual reproduction GO:0019953 36 0.018
schwann cell development GO:0014044 9 0.018
melanosome localization GO:0032400 21 0.018
polarized epithelial cell differentiation GO:0030859 4 0.018
ion transmembrane transport GO:0034220 91 0.018
regulation of blood pressure GO:0008217 1 0.018
odontogenesis of dentin containing tooth GO:0042475 1 0.017
pronephros morphogenesis GO:0072114 14 0.017
anterior lateral line nerve development GO:0048909 4 0.017
cellular biosynthetic process GO:0044249 286 0.017
melanosome transport GO:0032402 19 0.017
striated muscle cell development GO:0055002 108 0.017
regulation of developmental pigmentation GO:0048070 6 0.017
epidermal cell differentiation GO:0009913 36 0.017
cell migration GO:0016477 237 0.017
regulation of gene expression epigenetic GO:0040029 11 0.016
regulation of response to extracellular stimulus GO:0032104 1 0.016
cellular macromolecular complex assembly GO:0034622 24 0.016
cell substrate adhesion GO:0031589 4 0.016
regulation of macromolecule biosynthetic process GO:0010556 225 0.016
multicellular organism reproduction GO:0032504 35 0.016
photoreceptor cell fate commitment GO:0046552 1 0.016
protein complex biogenesis GO:0070271 30 0.016
regulation of transcription dna templated GO:0006355 213 0.015
chemotaxis GO:0006935 104 0.015
left right pattern formation GO:0060972 19 0.015
muscle tissue development GO:0060537 110 0.015
reproduction GO:0000003 40 0.015
regulation of gtp catabolic process GO:0033124 2 0.015
cardiac atrium morphogenesis GO:0003209 2 0.015
pole plasm assembly GO:0007315 4 0.015
somatic muscle development GO:0007525 4 0.015
pharyngeal muscle development GO:0043282 4 0.015
cell division GO:0051301 20 0.015
mesodermal cell differentiation GO:0048333 21 0.015
neuromast hair cell differentiation GO:0048886 12 0.015
regulation of protein maturation GO:1903317 10 0.015
regulation of programmed cell death GO:0043067 101 0.014
regulation of intracellular signal transduction GO:1902531 57 0.014
axis specification GO:0009798 43 0.014
positive regulation of metabolic process GO:0009893 108 0.014
establishment or maintenance of cell polarity GO:0007163 29 0.014
apoptotic process GO:0006915 116 0.014
positive regulation of macromolecule metabolic process GO:0010604 93 0.014
neural plate development GO:0001840 10 0.014
cytoskeleton dependent cytokinesis GO:0061640 3 0.014
response to light stimulus GO:0009416 46 0.014
homeostasis of number of cells within a tissue GO:0048873 4 0.013
spinal cord dorsal ventral patterning GO:0021513 5 0.013
organic cyclic compound metabolic process GO:1901360 301 0.013
proximal distal pattern formation GO:0009954 1 0.013
cognition GO:0050890 1 0.013
guanosine containing compound catabolic process GO:1901069 2 0.013
maternal determination of anterior posterior axis embryo GO:0008358 4 0.013
proepicardium development GO:0003342 4 0.013
inorganic cation transmembrane transport GO:0098662 50 0.013
response to stress GO:0006950 263 0.013
establishment of synaptic vesicle localization GO:0097480 1 0.013
smooth muscle contraction GO:0006939 2 0.013
axis elongation GO:0003401 31 0.013
negative regulation of macromolecule metabolic process GO:0010605 76 0.013
stem cell proliferation GO:0072089 4 0.013
regulation of retina development in camera type eye GO:1902866 2 0.013
synaptic transmission cholinergic GO:0007271 4 0.013
protein complex assembly GO:0006461 30 0.012
regulation of nucleoside metabolic process GO:0009118 2 0.012
establishment of spindle localization GO:0051293 12 0.012
multi organism reproductive process GO:0044703 36 0.012
mitotic cytokinesis GO:0000281 3 0.012
membrane organization GO:0061024 21 0.012
regulation of synapse assembly GO:0051963 3 0.012
cell proliferation GO:0008283 80 0.012
organelle fission GO:0048285 23 0.012
vestibular reflex GO:0060005 2 0.012
auditory receptor cell fate commitment GO:0009912 4 0.012
germ cell development GO:0007281 22 0.012
dendrite development GO:0016358 9 0.012
negative regulation of cell communication GO:0010648 96 0.012
cation transmembrane transport GO:0098655 65 0.012
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.012
regulation of gtpase activity GO:0043087 2 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
telencephalon development GO:0021537 14 0.012
inner ear receptor cell fate commitment GO:0060120 4 0.011
extracellular structure organization GO:0043062 27 0.011
regulation of cell development GO:0060284 100 0.011
regulation of apoptotic process GO:0042981 98 0.011
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.011
regulation of cellular component biogenesis GO:0044087 12 0.011
regulation of protein complex disassembly GO:0043244 1 0.011
small molecule metabolic process GO:0044281 77 0.011
positive regulation of transport GO:0051050 2 0.011
cellular response to external stimulus GO:0071496 2 0.011
regulation of cytokine production GO:0001817 3 0.011
cell fate specification GO:0001708 68 0.011
protein polymerization GO:0051258 4 0.011
transmission of nerve impulse GO:0019226 19 0.011
spindle localization GO:0051653 12 0.011
regulation of rna metabolic process GO:0051252 224 0.011
negative regulation of protein kinase b signaling GO:0051898 2 0.011
axonogenesis GO:0007409 152 0.011
regulation of nervous system development GO:0051960 90 0.011
central nervous system neuron development GO:0021954 29 0.011
skin development GO:0043588 54 0.010
death GO:0016265 121 0.010
establishment of cell polarity GO:0030010 18 0.010
muscle cell fate determination GO:0007521 1 0.010
developmental growth involved in morphogenesis GO:0060560 86 0.010
membrane fusion GO:0061025 2 0.010
myotube cell development GO:0014904 35 0.010
positive regulation of cellular catabolic process GO:0031331 3 0.010
olfactory bulb development GO:0021772 4 0.010
regulation of biosynthetic process GO:0009889 250 0.010
negative regulation of feeding behavior GO:2000252 2 0.010
centrosome organization GO:0051297 1 0.010

cc2d2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.165
nervous system disease DOID:863 0 0.017