Danio rerio

0 known processes

akap8l

A kinase (PRKA) anchor protein 8-like

(Aliases: zgc:85966)

akap8l biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
transcription dna templated GO:0006351 181 0.255
cellular macromolecule metabolic process GO:0044260 391 0.197
cellular macromolecule biosynthetic process GO:0034645 224 0.156
organelle organization GO:0006996 227 0.153
biosynthetic process GO:0009058 294 0.133
cellular nitrogen compound biosynthetic process GO:0044271 218 0.132
organic cyclic compound biosynthetic process GO:1901362 223 0.123
regulation of nucleic acid templated transcription GO:1903506 213 0.117
regulation of nitrogen compound metabolic process GO:0051171 251 0.112
embryo development ending in birth or egg hatching GO:0009792 271 0.111
aging GO:0007568 2 0.111
negative regulation of ras protein signal transduction GO:0046580 1 0.110
macromolecule biosynthetic process GO:0009059 227 0.109
response to chemical GO:0042221 320 0.108
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.099
negative regulation of cellular process GO:0048523 283 0.099
heterocycle metabolic process GO:0046483 290 0.097
nitrogen compound metabolic process GO:0006807 319 0.093
nucleic acid templated transcription GO:0097659 181 0.091
cellular biosynthetic process GO:0044249 286 0.088
rna biosynthetic process GO:0032774 181 0.088
cellular aromatic compound metabolic process GO:0006725 295 0.085
nuclear export GO:0051168 1 0.084
maintenance of location GO:0051235 4 0.084
signal transduction GO:0007165 455 0.082
cellular nitrogen compound metabolic process GO:0034641 290 0.081
regulation of protein transport GO:0051223 3 0.081
ubiquitin dependent protein catabolic process GO:0006511 3 0.081
regulation of transcription dna templated GO:0006355 213 0.080
intracellular signal transduction GO:0035556 85 0.079
regulation of establishment of protein localization GO:0070201 4 0.074
regulation of metabolic process GO:0019222 359 0.073
single organism nuclear import GO:1902593 3 0.072
negative regulation of metabolic process GO:0009892 86 0.071
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.071
negative regulation of cellular metabolic process GO:0031324 77 0.071
positive regulation of transport GO:0051050 2 0.069
regulation of cytoplasmic transport GO:1903649 4 0.067
cytokinesis GO:0000910 3 0.066
single organism organelle organization GO:1902589 199 0.066
regulation of biological quality GO:0065008 263 0.065
heterocycle biosynthetic process GO:0018130 215 0.065
homeostatic process GO:0042592 142 0.064
regulation of mrna splicing via spliceosome GO:0048024 3 0.064
cellular ketone metabolic process GO:0042180 11 0.063
positive regulation of cellular amine metabolic process GO:0033240 0 0.063
regulation of rna metabolic process GO:0051252 224 0.062
cellular component biogenesis GO:0044085 178 0.062
aromatic compound biosynthetic process GO:0019438 217 0.062
protein localization to nucleus GO:0034504 3 0.061
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.061
establishment of protein localization to organelle GO:0072594 4 0.060
regulation of cellular ketone metabolic process GO:0010565 7 0.060
cellular protein metabolic process GO:0044267 129 0.060
regulation of cellular amine metabolic process GO:0033238 0 0.057
nucleobase containing compound biosynthetic process GO:0034654 205 0.057
regulation of gene expression GO:0010468 265 0.057
regulation of erk1 and erk2 cascade GO:0070372 4 0.057
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.056
nuclear import GO:0051170 3 0.056
rna metabolic process GO:0016070 219 0.056
meiotic nuclear division GO:0007126 4 0.056
protein metabolic process GO:0019538 183 0.055
nucleocytoplasmic transport GO:0006913 4 0.054
protein import GO:0017038 3 0.053
amine metabolic process GO:0009308 2 0.053
regulation of mrna processing GO:0050684 3 0.053
alternative mrna splicing via spliceosome GO:0000380 1 0.053
spermatid differentiation GO:0048515 2 0.052
regulation of cellular biosynthetic process GO:0031326 245 0.050
larval development GO:0002164 2 0.050
macromolecular complex subunit organization GO:0043933 74 0.048
modification dependent protein catabolic process GO:0019941 3 0.048
rna splicing GO:0008380 16 0.048
oocyte anterior posterior axis specification GO:0007314 4 0.048
organic cyclic compound metabolic process GO:1901360 301 0.047
protein targeting to nucleus GO:0044744 3 0.047
protein import into nucleus GO:0006606 3 0.046
organic acid metabolic process GO:0006082 31 0.046
regulation of cellular amino acid metabolic process GO:0006521 0 0.046
cellular component assembly GO:0022607 170 0.045
gene expression GO:0010467 252 0.045
embryonic organ morphogenesis GO:0048562 274 0.045
regulation of biosynthetic process GO:0009889 250 0.044
regulation of primary metabolic process GO:0080090 311 0.044
nucleobase containing compound metabolic process GO:0006139 274 0.044
locomotion GO:0040011 313 0.043
positive regulation of cellular component biogenesis GO:0044089 3 0.043
regulation of intracellular protein transport GO:0033157 3 0.042
multicellular organism growth GO:0035264 4 0.042
cellular amine metabolic process GO:0044106 2 0.041
regulation of developmental process GO:0050793 247 0.040
regulation of nucleocytoplasmic transport GO:0046822 2 0.040
death GO:0016265 121 0.039
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.039
carboxylic acid metabolic process GO:0019752 22 0.039
organism emergence from protective structure GO:0071684 4 0.039
regulation of macromolecule metabolic process GO:0060255 317 0.038
cellular response to radiation GO:0071478 4 0.038
regulation of synapse organization GO:0050807 3 0.038
triglyceride homeostasis GO:0070328 2 0.038
protein k48 linked ubiquitination GO:0070936 1 0.037
chromatin modification GO:0016568 21 0.037
regulation of protein import into nucleus GO:0042306 2 0.037
regulation of multicellular organism growth GO:0040014 4 0.036
single organism localization GO:1902578 225 0.036
female sex differentiation GO:0046660 4 0.036
organic substance biosynthetic process GO:1901576 289 0.036
positive regulation of biological process GO:0048518 253 0.036
chromosome organization GO:0051276 31 0.036
stem cell proliferation GO:0072089 4 0.035
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.035
negative regulation of gene expression GO:0010629 65 0.035
regulation of meiotic cell cycle GO:0051445 1 0.035
nucleic acid metabolic process GO:0090304 244 0.034
hematopoietic or lymphoid organ development GO:0048534 191 0.034
protein polymerization GO:0051258 4 0.034
positive regulation of cellular process GO:0048522 201 0.034
oxoacid metabolic process GO:0043436 31 0.034
regulation of cell activation GO:0050865 1 0.034
spindle assembly GO:0051225 2 0.033
cellular component morphogenesis GO:0032989 336 0.033
synaptic growth at neuromuscular junction GO:0051124 2 0.033
regulation of epithelial cell proliferation GO:0050678 3 0.032
cell migration GO:0016477 237 0.032
regulation of protein targeting GO:1903533 2 0.032
negative regulation of rna metabolic process GO:0051253 48 0.032
mitotic cell cycle process GO:1903047 48 0.031
cell motility GO:0048870 244 0.031
lipid storage GO:0019915 1 0.031
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.030
regulation of cytokine production GO:0001817 3 0.030
neuroblast proliferation GO:0007405 2 0.030
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.030
transport GO:0006810 220 0.030
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.029
female gonad development GO:0008585 4 0.029
multi organism process GO:0051704 134 0.029
regulation of signal transduction GO:0009966 225 0.028
protein polyubiquitination GO:0000209 4 0.028
mitotic cell cycle GO:0000278 64 0.028
transcription from rna polymerase ii promoter GO:0006366 80 0.028
modification dependent macromolecule catabolic process GO:0043632 3 0.027
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.027
negative regulation of biological process GO:0048519 304 0.027
protein acetylation GO:0006473 2 0.027
negative regulation of cytoplasmic transport GO:1903650 2 0.027
negative regulation of nuclear division GO:0051784 3 0.027
apoptotic process GO:0006915 116 0.027
regulation of protein localization to nucleus GO:1900180 2 0.027
regulation of cell differentiation GO:0045595 142 0.027
microtubule depolymerization GO:0007019 1 0.026
cellular protein catabolic process GO:0044257 4 0.026
cellular localization GO:0051641 97 0.026
regulation of rna biosynthetic process GO:2001141 213 0.026
immune system development GO:0002520 191 0.026
regulation of cellular component organization GO:0051128 86 0.025
stem cell maintenance GO:0019827 4 0.025
locomotor rhythm GO:0045475 3 0.025
dna templated transcription elongation GO:0006354 3 0.025
nuclear transport GO:0051169 4 0.025
negative regulation of macromolecule metabolic process GO:0010605 76 0.025
rna processing GO:0006396 25 0.025
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.025
negative regulation of transcription dna templated GO:0045892 45 0.025
development of primary female sexual characteristics GO:0046545 4 0.024
regulation of protein complex assembly GO:0043254 3 0.024
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.024
negative regulation of protein phosphorylation GO:0001933 4 0.024
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.024
internal peptidyl lysine acetylation GO:0018393 2 0.024
embryonic organ development GO:0048568 381 0.024
oocyte development GO:0048599 14 0.024
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.023
rna localization GO:0006403 4 0.023
response to uv GO:0009411 3 0.023
regulation of protein catabolic process GO:0042176 1 0.023
negative regulation of intracellular transport GO:0032387 3 0.023
regulation of response to stimulus GO:0048583 269 0.023
regulation of macromolecule biosynthetic process GO:0010556 225 0.023
regulation of multicellular organismal process GO:0051239 277 0.022
adult behavior GO:0030534 2 0.022
negative regulation of defense response GO:0031348 2 0.022
response to stress GO:0006950 263 0.022
response to endogenous stimulus GO:0009719 83 0.022
centrosome cycle GO:0007098 1 0.022
response to external stimulus GO:0009605 264 0.021
blood vessel morphogenesis GO:0048514 216 0.021
organelle assembly GO:0070925 110 0.021
immune system process GO:0002376 241 0.021
regulation of microtubule cytoskeleton organization GO:0070507 3 0.021
establishment of localization GO:0051234 244 0.021
positive regulation of cell cycle GO:0045787 3 0.021
regulation of cellular metabolic process GO:0031323 320 0.020
macromolecule localization GO:0033036 54 0.020
negative regulation of mrna metabolic process GO:1903312 3 0.020
cellular amino acid metabolic process GO:0006520 7 0.020
cytoskeleton organization GO:0007010 96 0.020
positive regulation of transcription dna templated GO:0045893 57 0.020
acylglycerol homeostasis GO:0055090 2 0.020
peptidyl threonine modification GO:0018210 1 0.020
rna export from nucleus GO:0006405 1 0.019
regulation of histone methylation GO:0031060 3 0.019
regulation of synapse assembly GO:0051963 3 0.019
mrna metabolic process GO:0016071 20 0.019
translational initiation GO:0006413 3 0.019
multi organism cellular process GO:0044764 2 0.019
regulation of cell communication GO:0010646 232 0.019
positive regulation of jak stat cascade GO:0046427 2 0.019
intracellular transport GO:0046907 32 0.019
regulation of protein complex disassembly GO:0043244 1 0.019
negative regulation of biosynthetic process GO:0009890 55 0.019
negative regulation of dna metabolic process GO:0051053 4 0.019
organic acid catabolic process GO:0016054 3 0.019
cell cycle GO:0007049 93 0.018
oocyte differentiation GO:0009994 14 0.018
regulation of protein binding GO:0043393 3 0.018
response to hormone GO:0009725 48 0.018
negative regulation of mitosis GO:0045839 3 0.018
proteasomal protein catabolic process GO:0010498 2 0.018
regulation of signaling GO:0023051 235 0.018
maternal determination of anterior posterior axis embryo GO:0008358 4 0.018
regulation of chromosome segregation GO:0051983 1 0.018
positive regulation of cellular biosynthetic process GO:0031328 68 0.018
macromolecule modification GO:0043412 111 0.018
cellular response to external stimulus GO:0071496 2 0.018
programmed cell death GO:0012501 119 0.018
embryonic heart tube development GO:0035050 133 0.018
internal protein amino acid acetylation GO:0006475 2 0.018
response to organic substance GO:0010033 153 0.018
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.018
protein acylation GO:0043543 3 0.017
erk1 and erk2 cascade GO:0070371 4 0.017
regulation of wound healing GO:0061041 2 0.017
regulation of growth GO:0040008 42 0.017
protein depolymerization GO:0051261 1 0.017
peptidyl lysine methylation GO:0018022 3 0.017
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 10 0.017
regulation of protein depolymerization GO:1901879 1 0.017
sequestering of calcium ion GO:0051208 3 0.017
peptidyl threonine phosphorylation GO:0018107 1 0.017
cellular response to nutrient levels GO:0031669 2 0.017
localization of cell GO:0051674 244 0.017
glucose homeostasis GO:0042593 1 0.017
cytoskeleton dependent cytokinesis GO:0061640 3 0.017
nucleic acid transport GO:0050657 2 0.017
regulation of dendrite morphogenesis GO:0048814 3 0.017
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.017
stem cell division GO:0017145 1 0.017
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.017
compound eye development GO:0048749 2 0.017
protein alkylation GO:0008213 13 0.017
heart development GO:0007507 313 0.017
negative regulation of cytokine production GO:0001818 1 0.016
regulation of cellular protein catabolic process GO:1903362 1 0.016
cellular component movement GO:0006928 335 0.016
small molecule metabolic process GO:0044281 77 0.016
meiosis i GO:0007127 1 0.016
centrosome organization GO:0051297 1 0.016
peptidyl serine phosphorylation GO:0018105 1 0.016
negative regulation of signaling GO:0023057 96 0.016
positive regulation of rna metabolic process GO:0051254 59 0.016
negative regulation of rna splicing GO:0033119 1 0.016
regulation of protein metabolic process GO:0051246 56 0.016
negative regulation of kinase activity GO:0033673 4 0.016
microtubule polymerization or depolymerization GO:0031109 3 0.016
peptidyl lysine acetylation GO:0018394 2 0.016
positive regulation of chromosome organization GO:2001252 1 0.016
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.016
negative regulation of cell communication GO:0010648 96 0.016
female meiotic division GO:0007143 2 0.016
microtubule polymerization GO:0046785 2 0.016
generation of neurons GO:0048699 385 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.015
response to estrogen GO:0043627 27 0.015
developmental process involved in reproduction GO:0003006 27 0.015
interspecies interaction between organisms GO:0044419 4 0.015
regulation of cell cycle GO:0051726 52 0.015
neuron differentiation GO:0030182 353 0.015
regulation of dna templated transcription elongation GO:0032784 3 0.015
cellular protein complex disassembly GO:0043624 1 0.015
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.015
positive regulation of macromolecule metabolic process GO:0010604 93 0.015
cellular response to organic substance GO:0071310 105 0.015
positive regulation of cellular metabolic process GO:0031325 94 0.015
viral process GO:0016032 1 0.015
male meiosis GO:0007140 2 0.015
cilium organization GO:0044782 71 0.014
sensory organ development GO:0007423 393 0.014
small gtpase mediated signal transduction GO:0007264 8 0.014
negative regulation of protein kinase activity GO:0006469 4 0.014
positive regulation of dna metabolic process GO:0051054 1 0.014
atp catabolic process GO:0006200 4 0.014
cellular component disassembly GO:0022411 1 0.014
membrane fusion GO:0061025 2 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.014
regionalization GO:0003002 274 0.014
eye development GO:0001654 277 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.014
intracellular receptor signaling pathway GO:0030522 30 0.014
macromolecular complex disassembly GO:0032984 1 0.014
response to abiotic stimulus GO:0009628 122 0.014
regulation of microtubule depolymerization GO:0031114 1 0.014
protein complex disassembly GO:0043241 1 0.014
positive regulation of synapse assembly GO:0051965 1 0.014
negative regulation of epithelial cell proliferation GO:0050680 1 0.014
negative regulation of cytokine mediated signaling pathway GO:0001960 2 0.014
embryonic skeletal system development GO:0048706 97 0.014
positive regulation of histone modification GO:0031058 1 0.014
developmental growth GO:0048589 166 0.013
release of sequestered calcium ion into cytosol GO:0051209 3 0.013
morphogenesis of an epithelium GO:0002009 333 0.013
multicellular organism reproduction GO:0032504 35 0.013
microtubule based process GO:0007017 60 0.013
positive regulation of gene expression GO:0010628 71 0.013
chordate embryonic development GO:0043009 271 0.013
protein complex biogenesis GO:0070271 30 0.013
growth GO:0040007 174 0.013
chromosome organization involved in meiosis GO:0070192 1 0.013
regulation of cell death GO:0010941 103 0.013
pole plasm assembly GO:0007315 4 0.013
regulation of apoptotic process GO:0042981 98 0.013
response to hexose GO:0009746 3 0.013
ras protein signal transduction GO:0007265 7 0.013
stem cell development GO:0048864 82 0.013
organelle localization GO:0051640 49 0.013
regulation of organelle organization GO:0033043 29 0.013
embryonic digestive tract development GO:0048566 4 0.013
cellular response to stress GO:0033554 62 0.013
epithelial cell differentiation GO:0030855 116 0.013
regulation of multicellular organismal development GO:2000026 223 0.012
hemopoiesis GO:0030097 183 0.012
monocyte differentiation GO:0030224 2 0.012
angiogenesis GO:0001525 158 0.012
camera type eye development GO:0043010 222 0.012
production of molecular mediator of immune response GO:0002440 2 0.012
homeostasis of number of cells GO:0048872 62 0.012
positive regulation of multicellular organismal process GO:0051240 52 0.012
tissue remodeling GO:0048771 4 0.012
mrna export from nucleus GO:0006406 1 0.012
intracellular estrogen receptor signaling pathway GO:0030520 3 0.012
sequestering of metal ion GO:0051238 3 0.012
positive regulation of cell activation GO:0050867 1 0.012
negative regulation of signal transduction GO:0009968 94 0.012
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.012
g1 s transition of mitotic cell cycle GO:0000082 1 0.012
erythrocyte homeostasis GO:0034101 55 0.012
regulation of gene expression epigenetic GO:0040029 11 0.012
phosphorylation GO:0016310 69 0.012
regulation of cell division GO:0051302 12 0.012
rna 3 end processing GO:0031123 2 0.012
cellular protein localization GO:0034613 20 0.012
cell projection morphogenesis GO:0048858 244 0.012
single organism metabolic process GO:0044710 217 0.012
negative regulation of catabolic process GO:0009895 3 0.012
regulation of binding GO:0051098 3 0.012
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.012
protein heterooligomerization GO:0051291 1 0.012
tube morphogenesis GO:0035239 349 0.011
negative regulation of cellular biosynthetic process GO:0031327 55 0.011
cell projection organization GO:0030030 284 0.011
rna polyadenylation GO:0043631 2 0.011
mrna processing GO:0006397 14 0.011
cellular response to extracellular stimulus GO:0031668 2 0.011
telomere maintenance GO:0000723 1 0.011
negative regulation of dna replication GO:0008156 2 0.011
positive regulation of developmental process GO:0051094 50 0.011
negative regulation of mrna processing GO:0050686 1 0.011
anterior posterior pattern specification GO:0009952 152 0.011
cellular response to light stimulus GO:0071482 4 0.011
positive regulation of cellular catabolic process GO:0031331 3 0.011
regulation of endothelial cell proliferation GO:0001936 1 0.011
muscle cell differentiation GO:0042692 139 0.011
peptidyl lysine trimethylation GO:0018023 1 0.011
recombinational repair GO:0000725 1 0.011
tube closure GO:0060606 1 0.011
positive regulation of leukocyte differentiation GO:1902107 1 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.011
phototransduction GO:0007602 2 0.011
cellular response to chemical stimulus GO:0070887 157 0.011
protein modification process GO:0036211 100 0.011
mrna splicing via spliceosome GO:0000398 10 0.011
gamete generation GO:0007276 33 0.011
negative regulation of chromosome organization GO:2001251 1 0.011
response to vitamin GO:0033273 3 0.011
regulation of dendrite development GO:0050773 3 0.011
sensory organ morphogenesis GO:0090596 200 0.011
intracellular mrna localization GO:0008298 1 0.011
meiotic cell cycle process GO:1903046 3 0.011
digestive tract development GO:0048565 265 0.011
germ cell development GO:0007281 22 0.011
cell death GO:0008219 121 0.011
cell surface receptor signaling pathway GO:0007166 325 0.011
primary neural tube formation GO:0014020 1 0.011
negative regulation of response to stimulus GO:0048585 104 0.011
response to organic cyclic compound GO:0014070 51 0.011
phosphorus metabolic process GO:0006793 109 0.011
myeloid cell differentiation GO:0030099 86 0.011
peptidyl amino acid modification GO:0018193 16 0.011
b cell activation GO:0042113 2 0.010
organonitrogen compound metabolic process GO:1901564 74 0.010
histone h3 k4 methylation GO:0051568 2 0.010
embryonic heart tube morphogenesis GO:0003143 108 0.010
positive regulation of chromatin modification GO:1903310 1 0.010
cell morphogenesis GO:0000902 289 0.010
negative regulation of nucleic acid templated transcription GO:1903507 45 0.010
embryonic skeletal system morphogenesis GO:0048704 93 0.010
mitotic metaphase plate congression GO:0007080 1 0.010
meiotic chromosome segregation GO:0045132 3 0.010
small molecule catabolic process GO:0044282 3 0.010
positive regulation of rna biosynthetic process GO:1902680 57 0.010
blood circulation GO:0008015 87 0.010
negative regulation of multi organism process GO:0043901 3 0.010
macromolecular complex assembly GO:0065003 35 0.010
single organism cellular localization GO:1902580 46 0.010

akap8l disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.025
disease of cellular proliferation DOID:14566 0 0.025
organ system cancer DOID:0050686 0 0.025
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.013
motor neuron disease DOID:231 0 0.010
central nervous system disease DOID:331 0 0.010
amyotrophic lateral sclerosis DOID:332 0 0.010
neurodegenerative disease DOID:1289 0 0.010