Danio rerio

0 known processes

ptpn1

protein tyrosine phosphatase, non-receptor type 1

(Aliases: ptp1b,wu:fk54h03)

ptpn1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transport GO:0006810 220 0.341
Human
larval development GO:0002164 2 0.263
embryonic organ development GO:0048568 381 0.230
stem cell proliferation GO:0072089 4 0.212
positive regulation of transport GO:0051050 2 0.210
immune system process GO:0002376 241 0.145
nuclear transport GO:0051169 4 0.142
nucleocytoplasmic transport GO:0006913 4 0.134
hematopoietic or lymphoid organ development GO:0048534 191 0.125
establishment of localization GO:0051234 244 0.119
Human
tube morphogenesis GO:0035239 349 0.118
protein import GO:0017038 3 0.112
establishment of protein localization to organelle GO:0072594 4 0.108
response to external stimulus GO:0009605 264 0.107
immune system development GO:0002520 191 0.099
protein import into nucleus GO:0006606 3 0.098
organic cyclic compound metabolic process GO:1901360 301 0.097
positive regulation of cellular catabolic process GO:0031331 3 0.094
nuclear import GO:0051170 3 0.090
response to stress GO:0006950 263 0.086
Human
regulation of multicellular organismal process GO:0051239 277 0.085
chordate embryonic development GO:0043009 271 0.084
cellular nitrogen compound metabolic process GO:0034641 290 0.081
protein localization to nucleus GO:0034504 3 0.080
phagocytosis GO:0006909 3 0.078
cell surface receptor signaling pathway GO:0007166 325 0.078
Human Mouse Rat
single organism transport GO:0044765 206 0.077
aging GO:0007568 2 0.077
ubiquitin dependent protein catabolic process GO:0006511 3 0.075
autophagy GO:0006914 4 0.075
cellular component morphogenesis GO:0032989 336 0.074
regulation of biological quality GO:0065008 263 0.070
hemopoiesis GO:0030097 183 0.070
heterocycle metabolic process GO:0046483 290 0.069
cellular response to extracellular stimulus GO:0031668 2 0.069
single organism localization GO:1902578 225 0.068
protein targeting to nucleus GO:0044744 3 0.067
single organism nuclear import GO:1902593 3 0.066
leukocyte proliferation GO:0070661 1 0.065
blood vessel morphogenesis GO:0048514 216 0.063
Zebrafish
locomotion GO:0040011 313 0.062
organelle assembly GO:0070925 110 0.061
embryonic cranial skeleton morphogenesis GO:0048701 90 0.061
embryonic organ morphogenesis GO:0048562 274 0.061
blood vessel development GO:0001568 246 0.060
Zebrafish
regulation of multicellular organism growth GO:0040014 4 0.060
generation of neurons GO:0048699 385 0.059
lipid storage GO:0019915 1 0.058
signal transduction GO:0007165 455 0.057
Human Mouse Rat
cellular biosynthetic process GO:0044249 286 0.057
regulation of metabolic process GO:0019222 359 0.055
Mouse
maintenance of location GO:0051235 4 0.055
cellular response to external stimulus GO:0071496 2 0.055
regulation of cell shape GO:0008360 1 0.054
cellular response to starvation GO:0009267 1 0.053
embryonic skeletal system development GO:0048706 97 0.053
organic substance biosynthetic process GO:1901576 289 0.053
negative regulation of cellular catabolic process GO:0031330 3 0.051
macroautophagy GO:0016236 1 0.051
regulation of response to nutrient levels GO:0032107 1 0.051
cognition GO:0050890 1 0.050
cellular amine metabolic process GO:0044106 2 0.050
single organism membrane fusion GO:0044801 2 0.049
regulation of cytokine production GO:0001817 3 0.049
cellular response to nutrient levels GO:0031669 2 0.049
regulation of response to stimulus GO:0048583 269 0.048
Human Mouse Rat
regulation of protein transport GO:0051223 3 0.047
regulation of autophagy GO:0010506 3 0.047
eye development GO:0001654 277 0.047
regulation of circadian rhythm GO:0042752 4 0.047
microtubule organizing center organization GO:0031023 1 0.046
gtp metabolic process GO:0046039 4 0.046
compound eye development GO:0048749 2 0.046
skeletal system morphogenesis GO:0048705 102 0.046
regulation of developmental process GO:0050793 247 0.046
positive regulation of catabolic process GO:0009896 4 0.045
regulation of macromolecule metabolic process GO:0060255 317 0.045
Mouse
negative regulation of catabolic process GO:0009895 3 0.045
cellular component movement GO:0006928 335 0.045
alpha amino acid metabolic process GO:1901605 3 0.044
single organism organelle organization GO:1902589 199 0.044
Human
regulation of protein catabolic process GO:0042176 1 0.044
angiogenesis GO:0001525 158 0.044
organelle fusion GO:0048284 3 0.043
regulation of stem cell proliferation GO:0072091 2 0.043
stem cell fate commitment GO:0048865 1 0.043
heart development GO:0007507 313 0.042
nitrogen compound metabolic process GO:0006807 319 0.042
cellular macromolecule biosynthetic process GO:0034645 224 0.042
regulation of cell communication GO:0010646 232 0.042
Human Mouse Rat
regulation of establishment of protein localization GO:0070201 4 0.042
regulation of response to extracellular stimulus GO:0032104 1 0.042
amine metabolic process GO:0009308 2 0.042
regulation of skeletal muscle tissue development GO:0048641 4 0.042
response to external biotic stimulus GO:0043207 97 0.041
regulation of photoreceptor cell differentiation GO:0046532 2 0.041
cellular aromatic compound metabolic process GO:0006725 295 0.041
translational initiation GO:0006413 3 0.041
regulation of signaling GO:0023051 235 0.040
Human Mouse Rat
locomotor rhythm GO:0045475 3 0.040
ion transmembrane transport GO:0034220 91 0.040
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.040
enzyme linked receptor protein signaling pathway GO:0007167 106 0.039
Human Mouse Rat
modification dependent macromolecule catabolic process GO:0043632 3 0.038
response to topologically incorrect protein GO:0035966 2 0.038
Human
multicellular organism growth GO:0035264 4 0.038
positive regulation of gtpase activity GO:0043547 1 0.038
cellular macromolecule metabolic process GO:0044260 391 0.038
Human Mouse Rat
neuron differentiation GO:0030182 353 0.038
macromolecule biosynthetic process GO:0009059 227 0.037
cellular nitrogen compound biosynthetic process GO:0044271 218 0.036
regulation of gene expression GO:0010468 265 0.036
embryonic limb morphogenesis GO:0030326 2 0.036
regulation of multicellular organismal development GO:2000026 223 0.036
protein dephosphorylation GO:0006470 3 0.036
Human Mouse Rat
protein metabolic process GO:0019538 183 0.035
Human Mouse Rat
digestive tract development GO:0048565 265 0.035
centrosome organization GO:0051297 1 0.035
cellular protein catabolic process GO:0044257 4 0.035
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.035
entrainment of circadian clock GO:0009649 2 0.035
cellular amino acid metabolic process GO:0006520 7 0.034
nucleobase containing compound metabolic process GO:0006139 274 0.034
regulation of mrna processing GO:0050684 3 0.033
programmed cell death GO:0012501 119 0.033
cellular protein metabolic process GO:0044267 129 0.033
Human Mouse Rat
negative regulation of biological process GO:0048519 304 0.033
Mouse
regulation of cytoplasmic transport GO:1903649 4 0.032
regulation of cellular amine metabolic process GO:0033238 0 0.032
developmental programmed cell death GO:0010623 4 0.032
tor signaling GO:0031929 7 0.032
system process GO:0003008 185 0.032
peptidyl serine modification GO:0018209 2 0.032
peptidyl serine phosphorylation GO:0018105 1 0.032
negative regulation of autophagy GO:0010507 1 0.031
regulation of reproductive process GO:2000241 4 0.031
tissue remodeling GO:0048771 4 0.031
gtp catabolic process GO:0006184 2 0.031
adult behavior GO:0030534 2 0.031
regulation of metal ion transport GO:0010959 4 0.031
cellular component biogenesis GO:0044085 178 0.031
centrosome duplication GO:0051298 1 0.030
centrosome cycle GO:0007098 1 0.030
extrinsic apoptotic signaling pathway GO:0097191 3 0.030
skeletal system development GO:0001501 181 0.030
regulation of purine nucleotide catabolic process GO:0033121 2 0.030
regulation of programmed cell death GO:0043067 101 0.030
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.029
positive regulation of map kinase activity GO:0043406 3 0.029
response to other organism GO:0051707 97 0.029
regulation of macromolecule biosynthetic process GO:0010556 225 0.029
regulation of protein targeting GO:1903533 2 0.029
guanosine containing compound catabolic process GO:1901069 2 0.029
cell morphogenesis GO:0000902 289 0.029
macromolecule modification GO:0043412 111 0.029
Human Mouse Rat
neuroblast proliferation GO:0007405 2 0.029
modification dependent protein catabolic process GO:0019941 3 0.029
regulation of cell activation GO:0050865 1 0.028
regulation of intracellular protein transport GO:0033157 3 0.028
vesicle mediated transport GO:0016192 22 0.028
Human
digestive system development GO:0055123 289 0.028
neurological system process GO:0050877 62 0.028
cell motility GO:0048870 244 0.028
intracellular signal transduction GO:0035556 85 0.028
Mouse
morphogenesis of an epithelium GO:0002009 333 0.027
meiotic cell cycle process GO:1903046 3 0.027
response to abiotic stimulus GO:0009628 122 0.027
positive regulation of protein complex assembly GO:0031334 2 0.027
cellular response to stress GO:0033554 62 0.027
Human
protein polyubiquitination GO:0000209 4 0.027
guanosine containing compound metabolic process GO:1901068 4 0.026
regulation of localization GO:0032879 104 0.026
Human
positive regulation of gtp catabolic process GO:0033126 1 0.026
gastrulation GO:0007369 208 0.026
positive regulation of cellular component biogenesis GO:0044089 3 0.026
mononuclear cell proliferation GO:0032943 1 0.026
transmembrane transport GO:0055085 120 0.026
neuron development GO:0048666 262 0.026
mitochondrion organization GO:0007005 4 0.026
organic acid metabolic process GO:0006082 31 0.026
negative regulation of multicellular organismal process GO:0051241 69 0.026
response to salt stress GO:0009651 10 0.026
embryonic skeletal system morphogenesis GO:0048704 93 0.026
regulation of stem cell differentiation GO:2000736 4 0.026
regulation of nucleotide catabolic process GO:0030811 2 0.025
negative regulation of protein phosphorylation GO:0001933 4 0.025
Mouse
regulation of gtp catabolic process GO:0033124 2 0.025
positive regulation of nucleoside metabolic process GO:0045979 1 0.025
regulation of cell death GO:0010941 103 0.025
homeostatic process GO:0042592 142 0.025
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.024
photoreceptor cell differentiation GO:0046530 55 0.024
cellular component assembly GO:0022607 170 0.024
response to drug GO:0042493 3 0.024
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.024
meiosis i GO:0007127 1 0.024
lymphocyte proliferation GO:0046651 1 0.024
regulation of epithelial cell proliferation GO:0050678 3 0.024
regulation of protein localization to nucleus GO:1900180 2 0.023
positive regulation of apoptotic signaling pathway GO:2001235 1 0.023
response to bacterium GO:0009617 58 0.023
regulation of translational initiation GO:0006446 1 0.023
protein modification process GO:0036211 100 0.023
Human Mouse Rat
protein complex localization GO:0031503 1 0.023
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.023
organonitrogen compound metabolic process GO:1901564 74 0.023
response to chemical GO:0042221 320 0.023
Human Mouse Rat
positive regulation of nucleotide catabolic process GO:0030813 1 0.022
regulation of protein import into nucleus GO:0042306 2 0.022
embryo development ending in birth or egg hatching GO:0009792 271 0.022
negative regulation of metabolic process GO:0009892 86 0.022
Mouse
cellular protein modification process GO:0006464 100 0.022
Human Mouse Rat
signal transduction in absence of ligand GO:0038034 1 0.022
positive regulation of biological process GO:0048518 253 0.022
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.022
epithelial tube morphogenesis GO:0060562 148 0.022
regulation of biosynthetic process GO:0009889 250 0.022
positive regulation of stress activated mapk cascade GO:0032874 3 0.022
negative regulation of cell death GO:0060548 60 0.021
lateral inhibition GO:0046331 1 0.021
cellular biogenic amine metabolic process GO:0006576 2 0.021
regulation of neurogenesis GO:0050767 87 0.021
biosynthetic process GO:0009058 294 0.021
meiotic nuclear division GO:0007126 4 0.021
regulation of glucose transport GO:0010827 1 0.021
membrane invagination GO:0010324 1 0.021
regulation of protein complex assembly GO:0043254 3 0.021
small molecule metabolic process GO:0044281 77 0.021
head development GO:0060322 303 0.021
regulation of organelle assembly GO:1902115 4 0.021
specification of symmetry GO:0009799 204 0.021
stem cell division GO:0017145 1 0.021
cell fate commitment GO:0045165 99 0.021
response to osmotic stress GO:0006970 11 0.021
response to nutrient GO:0007584 3 0.021
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.021
regulation of response to stress GO:0080134 36 0.021
urogenital system development GO:0001655 97 0.020
regulation of apoptotic process GO:0042981 98 0.020
positive regulation of jnk cascade GO:0046330 3 0.020
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.020
organelle organization GO:0006996 227 0.020
Human
carboxylic acid metabolic process GO:0019752 22 0.020
multi organism process GO:0051704 134 0.020
phosphate containing compound metabolic process GO:0006796 108 0.020
Human Mouse Rat
negative regulation of nuclear division GO:0051784 3 0.020
chemosensory behavior GO:0007635 1 0.020
homeostasis of number of cells GO:0048872 62 0.020
apoptotic process involved in development GO:1902742 2 0.020
single organism cellular localization GO:1902580 46 0.020
apoptotic process GO:0006915 116 0.019
establishment of localization in cell GO:0051649 77 0.019
response to organic substance GO:0010033 153 0.019
Human Mouse Rat
post embryonic organ development GO:0048569 4 0.019
aromatic compound biosynthetic process GO:0019438 217 0.019
cellular modified amino acid metabolic process GO:0006575 3 0.019
negative regulation of reproductive process GO:2000242 3 0.019
appendage morphogenesis GO:0035107 56 0.019
localization of cell GO:0051674 244 0.019
actin filament based process GO:0030029 64 0.019
Human
vasculature development GO:0001944 278 0.019
Zebrafish
negative regulation of response to stimulus GO:0048585 104 0.019
Mouse
spermatid differentiation GO:0048515 2 0.019
metal ion transport GO:0030001 58 0.019
membrane fusion GO:0061025 2 0.019
glial cell proliferation GO:0014009 4 0.019
regulation of cellular component size GO:0032535 30 0.019
regulation of cell development GO:0060284 100 0.019
somite development GO:0061053 96 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
oxoacid metabolic process GO:0043436 31 0.018
cytokinesis GO:0000910 3 0.018
ion transport GO:0006811 114 0.018
spindle assembly GO:0051225 2 0.018
cell cycle g1 s phase transition GO:0044843 1 0.018
brain development GO:0007420 293 0.018
negative regulation of neural precursor cell proliferation GO:2000178 1 0.018
g1 s transition of mitotic cell cycle GO:0000082 1 0.018
negative regulation of cellular process GO:0048523 283 0.018
Mouse
rna metabolic process GO:0016070 219 0.018
cell projection organization GO:0030030 284 0.018
cytoskeleton organization GO:0007010 96 0.018
Human
negative regulation of developmental process GO:0051093 65 0.017
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.017
regulation of microtubule cytoskeleton organization GO:0070507 3 0.017
hormone secretion GO:0046879 2 0.017
single organism metabolic process GO:0044710 217 0.017
Mouse
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.017
rna biosynthetic process GO:0032774 181 0.017
post embryonic morphogenesis GO:0009886 4 0.017
synaptic growth at neuromuscular junction GO:0051124 2 0.017
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.017
negative regulation of cytoplasmic transport GO:1903650 2 0.017
positive regulation of secretion GO:0051047 1 0.017
negative regulation of muscle tissue development GO:1901862 2 0.017
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.017
entrainment of circadian clock by photoperiod GO:0043153 1 0.017
connective tissue development GO:0061448 99 0.017
neurotransmitter secretion GO:0007269 2 0.017
i kappab kinase nf kappab signaling GO:0007249 4 0.017
regulation of nucleoside metabolic process GO:0009118 2 0.017
taxis GO:0042330 109 0.016
nucleic acid metabolic process GO:0090304 244 0.016
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.016
regulation of hormone secretion GO:0046883 2 0.016
regulation of neural precursor cell proliferation GO:2000177 3 0.016
carbohydrate homeostasis GO:0033500 1 0.016
regulation of cellular ketone metabolic process GO:0010565 7 0.016
death GO:0016265 121 0.016
cell proliferation GO:0008283 80 0.016
response to radiation GO:0009314 51 0.016
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.016
negative regulation of gene expression GO:0010629 65 0.016
positive regulation of response to stimulus GO:0048584 80 0.016
response to monosaccharide GO:0034284 3 0.016
positive regulation of stem cell proliferation GO:2000648 1 0.016
b cell activation GO:0042113 2 0.016
cell projection morphogenesis GO:0048858 244 0.016
stem cell differentiation GO:0048863 117 0.016
positive regulation of chromatin modification GO:1903310 1 0.015
organonitrogen compound biosynthetic process GO:1901566 47 0.015
neurotransmitter transport GO:0006836 2 0.015
photoreceptor cell morphogenesis GO:0008594 1 0.015
regulation of carbohydrate metabolic process GO:0006109 4 0.015
nucleobase containing compound biosynthetic process GO:0034654 205 0.015
regulation of receptor mediated endocytosis GO:0048259 4 0.015
positive regulation of dna metabolic process GO:0051054 1 0.015
cell migration GO:0016477 237 0.015
cation transmembrane transport GO:0098655 65 0.015
negative regulation of programmed cell death GO:0043069 58 0.015
response to unfolded protein GO:0006986 2 0.015
Human
regulation of cell size GO:0008361 29 0.015
determination of bilateral symmetry GO:0009855 204 0.015
regulation of anatomical structure morphogenesis GO:0022603 130 0.015
intracellular transport GO:0046907 32 0.015
embryonic hemopoiesis GO:0035162 53 0.015
single organism intracellular transport GO:1902582 25 0.015
regulation of transport GO:0051049 45 0.015
Human
calcium ion import GO:0070509 4 0.015
circulatory system process GO:0003013 87 0.015
negative regulation of protein kinase activity GO:0006469 4 0.015
Mouse
regulation of cell projection assembly GO:0060491 4 0.015
inorganic cation transmembrane transport GO:0098662 50 0.015
negative regulation of mitosis GO:0045839 3 0.015
negative regulation of kinase activity GO:0033673 4 0.015
Mouse
cellular ketone metabolic process GO:0042180 11 0.015
peptide transport GO:0015833 1 0.015
regulation of gtpase activity GO:0043087 2 0.015
response to glucose GO:0009749 3 0.015
negative regulation of protein transport GO:0051224 3 0.014
regulation of dendrite morphogenesis GO:0048814 3 0.014
regulation of organ growth GO:0046620 3 0.014
stem cell maintenance GO:0019827 4 0.014
positive regulation of cytokine production GO:0001819 2 0.014
cellular response to chemical stimulus GO:0070887 157 0.014
Human Mouse Rat
regulation of cell fate specification GO:0042659 20 0.014
nucleic acid templated transcription GO:0097659 181 0.014
phosphorus metabolic process GO:0006793 109 0.014
Human Mouse Rat
regulation of glial cell proliferation GO:0060251 4 0.014
cell death GO:0008219 121 0.014
synaptic vesicle transport GO:0048489 1 0.014
positive regulation of immune effector process GO:0002699 3 0.014
gastrulation with mouth forming second GO:0001702 44 0.014
cell part morphogenesis GO:0032990 246 0.014
regulation of erk1 and erk2 cascade GO:0070372 4 0.014
Mouse
response to light stimulus GO:0009416 46 0.014
gliogenesis GO:0042063 45 0.014
endosome organization GO:0007032 2 0.014
regulation of tube size GO:0035150 2 0.014
regulation of blood vessel size GO:0050880 2 0.014
response to biotic stimulus GO:0009607 97 0.014
striated muscle cell differentiation GO:0051146 129 0.014
response to carbohydrate GO:0009743 3 0.014
nuclear division GO:0000280 23 0.014
somatic muscle development GO:0007525 4 0.014
smoothened signaling pathway GO:0007224 30 0.014
cortical actin cytoskeleton organization GO:0030866 1 0.014
odontogenesis of dentin containing tooth GO:0042475 1 0.014
regulation of jun kinase activity GO:0043506 3 0.014
macromolecule localization GO:0033036 54 0.014
cellular localization GO:0051641 97 0.014
regulation of sodium ion transport GO:0002028 2 0.014
wnt signaling pathway GO:0016055 80 0.014
regulation of primary metabolic process GO:0080090 311 0.013
Mouse
spermatid development GO:0007286 2 0.013
photoreceptor cell development GO:0042461 40 0.013
regulation of binding GO:0051098 3 0.013
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.013
response to uv GO:0009411 3 0.013
response to wounding GO:0009611 116 0.013
renal tubule morphogenesis GO:0061333 1 0.013
regulation of dna metabolic process GO:0051052 11 0.013
regulation of protein binding GO:0043393 3 0.013
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.013
mitotic cell cycle process GO:1903047 48 0.013
cellular amide metabolic process GO:0043603 4 0.013
digestive tract morphogenesis GO:0048546 231 0.013
toll like receptor signaling pathway GO:0002224 4 0.013
positive regulation of secretion by cell GO:1903532 1 0.013
phagocytosis engulfment GO:0006911 1 0.013
cellular response to vascular endothelial growth factor stimulus GO:0035924 3 0.013
striated muscle tissue development GO:0014706 110 0.013
negative regulation of intracellular transport GO:0032387 3 0.013
cation transport GO:0006812 81 0.013
female gonad development GO:0008585 4 0.013
growth GO:0040007 174 0.013
golgi vesicle transport GO:0048193 3 0.013
peptide metabolic process GO:0006518 1 0.013
tube closure GO:0060606 1 0.013
cellular response to unfolded protein GO:0034620 2 0.013
Human
small gtpase mediated signal transduction GO:0007264 8 0.013
positive regulation of cytoskeleton organization GO:0051495 3 0.013
catabolic process GO:0009056 32 0.013
positive regulation of cell activation GO:0050867 1 0.013
cellular component disassembly GO:0022411 1 0.013
leukocyte homeostasis GO:0001776 2 0.012
nerve development GO:0021675 45 0.012
organic substance transport GO:0071702 58 0.012
muscle structure development GO:0061061 196 0.012
negative regulation of epithelial cell proliferation GO:0050680 1 0.012
positive regulation of leukocyte mediated immunity GO:0002705 1 0.012
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.012
positive regulation of neuron death GO:1901216 1 0.012
positive regulation of notch signaling pathway GO:0045747 3 0.012
negative regulation of sequestering of calcium ion GO:0051283 4 0.012
cellular response to biotic stimulus GO:0071216 3 0.012
forebrain cell migration GO:0021885 1 0.012
regulation of cellular protein catabolic process GO:1903362 1 0.012
sensory organ morphogenesis GO:0090596 200 0.012
rna localization GO:0006403 4 0.012
nuclear export GO:0051168 1 0.012
developmental growth GO:0048589 166 0.012
regulation of cell morphogenesis GO:0022604 42 0.012
regulation of neuron differentiation GO:0045664 56 0.012
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.012
proteasomal protein catabolic process GO:0010498 2 0.012
regulation of protein metabolic process GO:0051246 56 0.012
Mouse
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.012
regulation of oocyte development GO:0060281 3 0.012
regulation of mrna splicing via spliceosome GO:0048024 3 0.012
cellular response to topologically incorrect protein GO:0035967 2 0.012
Human
cell aging GO:0007569 2 0.012
protein polymerization GO:0051258 4 0.012
positive regulation of histone modification GO:0031058 1 0.012
mitochondrial transport GO:0006839 2 0.012
response to inorganic substance GO:0010035 38 0.012
regulation of glucose import GO:0046324 1 0.012
cranial nerve development GO:0021545 42 0.012
macromolecular complex disassembly GO:0032984 1 0.012
nephron epithelium morphogenesis GO:0072088 1 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
er to golgi vesicle mediated transport GO:0006888 1 0.012
regulation of synaptic plasticity GO:0048167 1 0.012
female sex differentiation GO:0046660 4 0.012
positive regulation of cell cycle GO:0045787 3 0.012
regulation of muscle contraction GO:0006937 3 0.012
cortical cytoskeleton organization GO:0030865 1 0.012
negative regulation of signal transduction GO:0009968 94 0.012
Mouse
renal system development GO:0072001 94 0.012
carbohydrate biosynthetic process GO:0016051 1 0.012
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.011
erk1 and erk2 cascade GO:0070371 4 0.011
Mouse
sequestering of metal ion GO:0051238 3 0.011
release of sequestered calcium ion into cytosol GO:0051209 3 0.011
regulation of cellular metabolic process GO:0031323 320 0.011
Mouse
ovulation cycle process GO:0022602 2 0.011
positive regulation of neuron apoptotic process GO:0043525 1 0.011
regulation of rna biosynthetic process GO:2001141 213 0.011
action potential GO:0001508 19 0.011
central nervous system development GO:0007417 387 0.011
zymogen activation GO:0031638 3 0.011
energy reserve metabolic process GO:0006112 2 0.011
response to hexose GO:0009746 3 0.011
response to nutrient levels GO:0031667 10 0.011
endoplasmic reticulum unfolded protein response GO:0030968 2 0.011
Human
protein localization to plasma membrane GO:0072659 1 0.011
actin filament polymerization GO:0030041 2 0.011
apoptotic signaling pathway GO:0097190 23 0.011
cellular response to radiation GO:0071478 4 0.011
cell morphogenesis involved in differentiation GO:0000904 195 0.011
eye morphogenesis GO:0048592 144 0.011
regulation of wound healing GO:0061041 2 0.011
gene expression GO:0010467 252 0.011

ptpn1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.051
musculoskeletal system disease DOID:17 0 0.032
colon carcinoma DOID:1520 0 0.026
large intestine cancer DOID:5672 0 0.026
colon cancer DOID:219 0 0.026
gastrointestinal system cancer DOID:3119 0 0.026
intestinal cancer DOID:10155 0 0.026
cancer DOID:162 0 0.026
disease of cellular proliferation DOID:14566 0 0.026
organ system cancer DOID:0050686 0 0.026
colorectal cancer DOID:9256 0 0.026
nervous system disease DOID:863 0 0.016
myopathy DOID:423 0 0.015
muscular disease DOID:0080000 0 0.015
muscle tissue disease DOID:66 0 0.015