Danio rerio

0 known processes

tia1

cytotoxic granule-associated RNA binding protein 1

(Aliases: MGC55520,zgc:55520,wu:fb73d10,fb73d10,wu:fc02b04)

tia1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular biosynthetic process GO:0031326 245 0.416
regulation of neural precursor cell proliferation GO:2000177 3 0.354
macromolecule biosynthetic process GO:0009059 227 0.343
generation of neurons GO:0048699 385 0.276
regulation of biosynthetic process GO:0009889 250 0.262
cellular macromolecule metabolic process GO:0044260 391 0.246
Human Yeast Fly
regulation of macromolecule biosynthetic process GO:0010556 225 0.242
positive regulation of cell cycle GO:0045787 3 0.222
regulation of rna metabolic process GO:0051252 224 0.206
Human Fly
cellular macromolecule biosynthetic process GO:0034645 224 0.206
sensory organ development GO:0007423 393 0.201
cellular protein catabolic process GO:0044257 4 0.200
regulation of primary metabolic process GO:0080090 311 0.196
Human Fly
cellular biosynthetic process GO:0044249 286 0.190
neuron differentiation GO:0030182 353 0.189
biosynthetic process GO:0009058 294 0.185
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.183
regulation of mrna splicing via spliceosome GO:0048024 3 0.179
Human Fly
regulation of stem cell proliferation GO:0072091 2 0.177
negative regulation of cellular process GO:0048523 283 0.172
cellular nitrogen compound biosynthetic process GO:0044271 218 0.172
cellular component morphogenesis GO:0032989 336 0.169
negative regulation of neural precursor cell proliferation GO:2000178 1 0.164
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.161
rna metabolic process GO:0016070 219 0.161
Human Yeast Fly
positive regulation of cellular process GO:0048522 201 0.156
nucleic acid templated transcription GO:0097659 181 0.156
negative regulation of cell differentiation GO:0045596 46 0.152
microtubule organizing center organization GO:0031023 1 0.148
regulation of circadian rhythm GO:0042752 4 0.148
regulation of metabolic process GO:0019222 359 0.145
Human Yeast Fly
regulation of macromolecule metabolic process GO:0060255 317 0.144
Human Yeast Fly
modification dependent macromolecule catabolic process GO:0043632 3 0.142
regulation of transcription dna templated GO:0006355 213 0.139
signal transduction GO:0007165 455 0.135
vasculature development GO:0001944 278 0.132
regulation of nitrogen compound metabolic process GO:0051171 251 0.130
Human Fly
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.129
larval development GO:0002164 2 0.123
Worm
protein dephosphorylation GO:0006470 3 0.118
regulation of cell differentiation GO:0045595 142 0.115
transcription dna templated GO:0006351 181 0.111
organic substance biosynthetic process GO:1901576 289 0.108
cellular nitrogen compound metabolic process GO:0034641 290 0.105
Human Yeast Fly
stem cell division GO:0017145 1 0.105
protein metabolic process GO:0019538 183 0.104
proteasomal protein catabolic process GO:0010498 2 0.103
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.102
neuroblast proliferation GO:0007405 2 0.099
tube morphogenesis GO:0035239 349 0.099
gene expression GO:0010467 252 0.098
Human Yeast Fly
stem cell proliferation GO:0072089 4 0.098
regulation of response to stimulus GO:0048583 269 0.094
epithelial tube morphogenesis GO:0060562 148 0.093
heterocycle biosynthetic process GO:0018130 215 0.091
cell part morphogenesis GO:0032990 246 0.090
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.088
Human Fly
regulation of neurogenesis GO:0050767 87 0.087
blood vessel development GO:0001568 246 0.086
nucleic acid metabolic process GO:0090304 244 0.085
Human Yeast Fly
modification dependent protein catabolic process GO:0019941 3 0.085
regulation of protein catabolic process GO:0042176 1 0.085
regulation of cellular metabolic process GO:0031323 320 0.085
Human Fly
regulation of mrna processing GO:0050684 3 0.083
Human Fly
regulation of gene expression GO:0010468 265 0.083
Human Yeast Fly
cell projection organization GO:0030030 284 0.080
morphogenesis of an epithelium GO:0002009 333 0.079
neuron projection morphogenesis GO:0048812 161 0.078
regulation of multicellular organismal development GO:2000026 223 0.077
nucleobase containing compound metabolic process GO:0006139 274 0.073
Human Yeast Fly
regulation of nucleic acid templated transcription GO:1903506 213 0.072
regulation of developmental process GO:0050793 247 0.072
regulation of protein localization to nucleus GO:1900180 2 0.072
aromatic compound biosynthetic process GO:0019438 217 0.072
protein localization to nucleus GO:0034504 3 0.071
rna biosynthetic process GO:0032774 181 0.070
organic cyclic compound metabolic process GO:1901360 301 0.069
Human Yeast Fly
ubiquitin dependent protein catabolic process GO:0006511 3 0.069
cytoskeleton dependent cytokinesis GO:0061640 3 0.068
cell surface receptor signaling pathway GO:0007166 325 0.068
regulation of cellular protein metabolic process GO:0032268 52 0.068
alternative mrna splicing via spliceosome GO:0000380 1 0.067
Fly
nucleobase containing compound biosynthetic process GO:0034654 205 0.064
mitotic cell cycle GO:0000278 64 0.062
cell morphogenesis GO:0000902 289 0.062
blood vessel morphogenesis GO:0048514 216 0.062
aging GO:0007568 2 0.062
mitotic nuclear division GO:0007067 18 0.061
negative regulation of developmental process GO:0051093 65 0.061
organelle organization GO:0006996 227 0.060
Yeast
regulation of multicellular organismal process GO:0051239 277 0.060
positive regulation of biological process GO:0048518 253 0.058
regulation of protein complex assembly GO:0043254 3 0.056
regulation of nervous system development GO:0051960 90 0.056
regulation of rna biosynthetic process GO:2001141 213 0.056
cell projection morphogenesis GO:0048858 244 0.054
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.054
cellular component assembly GO:0022607 170 0.053
Yeast
embryo development ending in birth or egg hatching GO:0009792 271 0.053
Worm
regionalization GO:0003002 274 0.053
negative regulation of chromosome organization GO:2001251 1 0.053
cellular protein metabolic process GO:0044267 129 0.053
cellular aromatic compound metabolic process GO:0006725 295 0.052
Human Yeast Fly
axon development GO:0061564 166 0.051
negative regulation of multicellular organismal process GO:0051241 69 0.051
cell fate commitment GO:0045165 99 0.050
neuron projection development GO:0031175 180 0.050
negative regulation of nucleic acid templated transcription GO:1903507 45 0.049
organic cyclic compound biosynthetic process GO:1901362 223 0.048
dorsal ventral pattern formation GO:0009953 125 0.048
single organism metabolic process GO:0044710 217 0.048
negative regulation of biological process GO:0048519 304 0.048
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.046
neuron development GO:0048666 262 0.046
cell morphogenesis involved in differentiation GO:0000904 195 0.045
regulation of localization GO:0032879 104 0.045
regulation of cellular protein catabolic process GO:1903362 1 0.045
cellular component biogenesis GO:0044085 178 0.043
Yeast
intracellular receptor signaling pathway GO:0030522 30 0.043
nucleocytoplasmic transport GO:0006913 4 0.043
centrosome cycle GO:0007098 1 0.042
negative regulation of neurogenesis GO:0050768 20 0.041
nitrogen compound metabolic process GO:0006807 319 0.041
Human Yeast Fly
organic substance catabolic process GO:1901575 28 0.041
Yeast
positive regulation of translation GO:0045727 1 0.039
g2 m transition of mitotic cell cycle GO:0000086 4 0.038
regulation of stem cell differentiation GO:2000736 4 0.038
heterocycle metabolic process GO:0046483 290 0.038
Human Yeast Fly
negative regulation of gene expression GO:0010629 65 0.037
muscle structure development GO:0061061 196 0.037
translational initiation GO:0006413 3 0.037
phosphorus metabolic process GO:0006793 109 0.037
stem cell maintenance GO:0019827 4 0.036
microtubule based process GO:0007017 60 0.036
cellular component movement GO:0006928 335 0.035
proteolysis GO:0006508 38 0.034
macromolecular complex subunit organization GO:0043933 74 0.034
Yeast
rna localization GO:0006403 4 0.034
negative regulation of cell development GO:0010721 26 0.034
regulation of cell proliferation GO:0042127 37 0.033
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.033
Fly
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.033
regulation of molecular function GO:0065009 70 0.033
cellular protein modification process GO:0006464 100 0.032
positive regulation of macromolecule metabolic process GO:0010604 93 0.032
locomotion GO:0040011 313 0.032
Worm
regulation of reproductive process GO:2000241 4 0.032
protein modification process GO:0036211 100 0.032
response to external stimulus GO:0009605 264 0.031
regulation of cell projection assembly GO:0060491 4 0.031
axis specification GO:0009798 43 0.031
regulation of nucleoside metabolic process GO:0009118 2 0.030
multi organism process GO:0051704 134 0.030
regulation of cell communication GO:0010646 232 0.030
regulation of cell development GO:0060284 100 0.030
meiotic nuclear division GO:0007126 4 0.029
negative regulation of cellular catabolic process GO:0031330 3 0.029
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.028
chromosome organization GO:0051276 31 0.028
negative regulation of macromolecule metabolic process GO:0010605 76 0.028
negative regulation of transcription dna templated GO:0045892 45 0.028
protein complex disassembly GO:0043241 1 0.028
guanosine containing compound metabolic process GO:1901068 4 0.028
cell cycle g2 m phase transition GO:0044839 4 0.028
negative regulation of cellular biosynthetic process GO:0031327 55 0.028
regulation of signaling GO:0023051 235 0.028
muscle organ development GO:0007517 101 0.027
cell proliferation GO:0008283 80 0.027
oxoacid metabolic process GO:0043436 31 0.027
cellular component disassembly GO:0022411 1 0.027
amine metabolic process GO:0009308 2 0.027
axonogenesis GO:0007409 152 0.026
lamellipodium assembly GO:0030032 1 0.026
regulation of chromosome segregation GO:0051983 1 0.026
response to stress GO:0006950 263 0.026
rna export from nucleus GO:0006405 1 0.026
macromolecular complex disassembly GO:0032984 1 0.026
behavior GO:0007610 74 0.025
regulation of cytokine production GO:0001817 3 0.025
positive regulation of map kinase activity GO:0043406 3 0.025
wnt signaling pathway GO:0016055 80 0.025
cell growth GO:0016049 57 0.025
cellular response to extracellular stimulus GO:0031668 2 0.025
response to abiotic stimulus GO:0009628 122 0.025
cellular response to stress GO:0033554 62 0.025
response to chemical GO:0042221 320 0.025
multicellular organism growth GO:0035264 4 0.025
carboxylic acid metabolic process GO:0019752 22 0.025
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.024
organic acid metabolic process GO:0006082 31 0.024
nuclear transport GO:0051169 4 0.024
actin polymerization or depolymerization GO:0008154 2 0.024
negative regulation of cellular metabolic process GO:0031324 77 0.024
nuclear division GO:0000280 23 0.023
macromolecule modification GO:0043412 111 0.023
chemotaxis GO:0006935 104 0.023
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.023
protein import GO:0017038 3 0.023
endothelium development GO:0003158 25 0.023
cellular response to organic substance GO:0071310 105 0.022
regulation of protein metabolic process GO:0051246 56 0.022
organonitrogen compound metabolic process GO:1901564 74 0.022
regulation of nucleotide catabolic process GO:0030811 2 0.022
mitochondrion organization GO:0007005 4 0.022
development of primary female sexual characteristics GO:0046545 4 0.022
cellular response to external stimulus GO:0071496 2 0.022
peptide transport GO:0015833 1 0.021
ameboidal type cell migration GO:0001667 143 0.021
regulation of wnt signaling pathway GO:0030111 53 0.021
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.021
positive regulation of metabolic process GO:0009893 108 0.021
regulation of cell cycle GO:0051726 52 0.021
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.021
central nervous system development GO:0007417 387 0.021
cytokinesis GO:0000910 3 0.021
regulation of translational initiation GO:0006446 1 0.021
eye development GO:0001654 277 0.021
response to topologically incorrect protein GO:0035966 2 0.020
nucleoside monophosphate catabolic process GO:0009125 4 0.020
negative regulation of catabolic process GO:0009895 3 0.020
negative regulation of metabolic process GO:0009892 86 0.020
cellular response to starvation GO:0009267 1 0.020
lamellipodium organization GO:0097581 1 0.020
actin filament polymerization GO:0030041 2 0.020
catabolic process GO:0009056 32 0.020
Yeast
mitotic cell cycle checkpoint GO:0007093 5 0.020
protein targeting to nucleus GO:0044744 3 0.020
cellular response to chemical stimulus GO:0070887 157 0.020
single organism organelle organization GO:1902589 199 0.019
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.019
dorsal ventral axis specification GO:0009950 14 0.019
organelle fission GO:0048285 23 0.019
negative regulation of cell cycle GO:0045786 14 0.019
positive regulation of catabolic process GO:0009896 4 0.019
neuron projection guidance GO:0097485 86 0.019
dna templated transcription initiation GO:0006352 1 0.019
digestive tract morphogenesis GO:0048546 231 0.019
wound healing GO:0042060 90 0.018
regulation of signal transduction GO:0009966 225 0.018
axon guidance GO:0007411 86 0.018
negative regulation of rna metabolic process GO:0051253 48 0.018
brain development GO:0007420 293 0.018
positive regulation of cellular component biogenesis GO:0044089 3 0.018
carbohydrate homeostasis GO:0033500 1 0.018
regulation of cellular ketone metabolic process GO:0010565 7 0.018
meiotic cell cycle process GO:1903046 3 0.018
cellular response to topologically incorrect protein GO:0035967 2 0.018
rna transport GO:0050658 2 0.018
regulation of cellular component organization GO:0051128 86 0.018
regulation of multicellular organism growth GO:0040014 4 0.018
maintenance of location GO:0051235 4 0.018
stem cell development GO:0048864 82 0.018
guanosine containing compound catabolic process GO:1901069 2 0.018
stem cell fate commitment GO:0048865 1 0.017
positive regulation of cellular catabolic process GO:0031331 3 0.017
stem cell differentiation GO:0048863 117 0.017
mitotic dna integrity checkpoint GO:0044774 4 0.017
hormone transport GO:0009914 2 0.017
purine nucleoside monophosphate catabolic process GO:0009128 4 0.017
ribonucleoside monophosphate catabolic process GO:0009158 4 0.017
establishment of protein localization to organelle GO:0072594 4 0.017
single organism nuclear import GO:1902593 3 0.017
regulation of cell projection organization GO:0031344 44 0.017
regulation of binding GO:0051098 3 0.017
protein polymerization GO:0051258 4 0.017
cellular response to nutrient levels GO:0031669 2 0.017
positive regulation of immune effector process GO:0002699 3 0.016
nuclear import GO:0051170 3 0.016
regulation of organelle organization GO:0033043 29 0.016
specification of symmetry GO:0009799 204 0.016
regulation of purine nucleotide catabolic process GO:0033121 2 0.016
cellular amine metabolic process GO:0044106 2 0.016
regulation of catalytic activity GO:0050790 55 0.016
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.016
growth GO:0040007 174 0.016
Worm
regulation of protein polymerization GO:0032271 2 0.016
regulation of nucleocytoplasmic transport GO:0046822 2 0.016
nucleic acid transport GO:0050657 2 0.015
positive regulation of transport GO:0051050 2 0.015
small molecule metabolic process GO:0044281 77 0.015
protein complex assembly GO:0006461 30 0.015
digestive tract development GO:0048565 265 0.015
autophagy GO:0006914 4 0.015
response to hexose GO:0009746 3 0.015
response to ketone GO:1901654 1 0.015
female gonad development GO:0008585 4 0.015
regulation of cellular amine metabolic process GO:0033238 0 0.015
female sex differentiation GO:0046660 4 0.015
synaptic vesicle transport GO:0048489 1 0.015
establishment of rna localization GO:0051236 3 0.015
mitotic cell cycle process GO:1903047 48 0.015
positive regulation of nucleoside metabolic process GO:0045979 1 0.015
extrinsic apoptotic signaling pathway GO:0097191 3 0.015
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.015
response to radiation GO:0009314 51 0.014
neuron projection extension GO:1990138 45 0.014
locomotor rhythm GO:0045475 3 0.014
cell death GO:0008219 121 0.014
cell projection assembly GO:0030031 64 0.014
response to unfolded protein GO:0006986 2 0.014
phosphate containing compound metabolic process GO:0006796 108 0.014
homeostatic process GO:0042592 142 0.014
g1 s transition of mitotic cell cycle GO:0000082 1 0.014
cell motility GO:0048870 244 0.014
protein n linked glycosylation GO:0006487 1 0.014
mrna transport GO:0051028 2 0.014
taxis GO:0042330 109 0.014
mrna export from nucleus GO:0006406 1 0.014
response to carbohydrate GO:0009743 3 0.014
nuclear envelope organization GO:0006998 2 0.014
hormone secretion GO:0046879 2 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
regulation of wound healing GO:0061041 2 0.013
regulation of cell activation GO:0050865 1 0.013
centrosome organization GO:0051297 1 0.013
negative regulation of rna biosynthetic process GO:1902679 45 0.013
lateral inhibition GO:0046331 1 0.013
gtp catabolic process GO:0006184 2 0.013
regulation of tube size GO:0035150 2 0.013
localization of cell GO:0051674 244 0.013
cellular catabolic process GO:0044248 27 0.013
Yeast
transcription from rna polymerase ii promoter GO:0006366 80 0.013
i kappab kinase nf kappab signaling GO:0007249 4 0.013
peptidyl serine phosphorylation GO:0018105 1 0.013
negative regulation of stem cell differentiation GO:2000737 2 0.013
positive regulation of cell activation GO:0050867 1 0.013
phagocytosis GO:0006909 3 0.013
circadian rhythm GO:0007623 19 0.013
regulation of gtpase activity GO:0043087 2 0.013
negative regulation of nervous system development GO:0051961 22 0.013
enzyme linked receptor protein signaling pathway GO:0007167 106 0.013
endoplasmic reticulum unfolded protein response GO:0030968 2 0.013
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
positive regulation of cellular biosynthetic process GO:0031328 68 0.013
regulation of epithelial cell proliferation GO:0050678 3 0.013
entrainment of circadian clock by photoperiod GO:0043153 1 0.013
negative regulation of rna splicing GO:0033119 1 0.013
neural precursor cell proliferation GO:0061351 20 0.013
mrna stabilization GO:0048255 4 0.013
gtp metabolic process GO:0046039 4 0.013
antimicrobial humoral response GO:0019730 2 0.012
activation of mapk activity GO:0000187 3 0.012
response to organic substance GO:0010033 153 0.012
positive regulation of jak stat cascade GO:0046427 2 0.012
posttranscriptional regulation of gene expression GO:0010608 14 0.012
Yeast
positive regulation of nucleic acid templated transcription GO:1903508 57 0.012
nucleobase containing compound transport GO:0015931 2 0.012
negative regulation of signal transduction GO:0009968 94 0.012
developmental growth GO:0048589 166 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.012
negative regulation of translation GO:0017148 1 0.012
positive regulation of cytoskeleton organization GO:0051495 3 0.012
golgi vesicle transport GO:0048193 3 0.012
cellular ketone metabolic process GO:0042180 11 0.012
positive regulation of rna biosynthetic process GO:1902680 57 0.012
regulation of synapse organization GO:0050807 3 0.012
regulation of epithelial to mesenchymal transition GO:0010717 3 0.012
regulation of epidermis development GO:0045682 2 0.012
regulation of meiotic cell cycle GO:0051445 1 0.012
intracellular signal transduction GO:0035556 85 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.012
regulation of cell shape GO:0008360 1 0.011
cell migration GO:0016477 237 0.011
mitotic cytokinesis GO:0000281 3 0.011
defense response GO:0006952 47 0.011
positive regulation of jun kinase activity GO:0043507 2 0.011
response to glucose GO:0009749 3 0.011
regulation of growth GO:0040008 42 0.011
skeletal system development GO:0001501 181 0.011
synaptic vesicle localization GO:0097479 1 0.011
convergent extension GO:0060026 118 0.011
positive regulation of nucleotide catabolic process GO:0030813 1 0.011
cilium morphogenesis GO:0060271 85 0.011
response to other organism GO:0051707 97 0.011
developmental growth involved in morphogenesis GO:0060560 86 0.011
glucose homeostasis GO:0042593 1 0.011
cell cycle g1 s phase transition GO:0044843 1 0.011
positive regulation of cytokine production GO:0001819 2 0.011
positive regulation of protein complex assembly GO:0031334 2 0.011
response to fluid shear stress GO:0034405 2 0.011
phagocytosis engulfment GO:0006911 1 0.011
regulation of cytoplasmic transport GO:1903649 4 0.011
positive regulation of biosynthetic process GO:0009891 68 0.011
response to lipid GO:0033993 60 0.011
regulation of jak stat cascade GO:0046425 3 0.011
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.011
retina development in camera type eye GO:0060041 146 0.011
response to external biotic stimulus GO:0043207 97 0.011
keratinocyte differentiation GO:0030216 0 0.011
negative regulation of chromatin modification GO:1903309 1 0.011
leukocyte proliferation GO:0070661 1 0.011
negative regulation of mitotic cell cycle GO:0045930 11 0.011
negative regulation of multi organism process GO:0043901 3 0.010
cellular protein complex disassembly GO:0043624 1 0.010
positive regulation of gene expression GO:0010628 71 0.010
determination of bilateral symmetry GO:0009855 204 0.010
regulation of receptor activity GO:0010469 2 0.010
cell cycle process GO:0022402 53 0.010
regulation of protein complex disassembly GO:0043244 1 0.010
positive regulation of leukocyte mediated immunity GO:0002705 1 0.010
liver development GO:0001889 96 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.010
cellular response to biotic stimulus GO:0071216 3 0.010
regulation of cell cycle g2 m phase transition GO:1902749 4 0.010
regulation of cellular component movement GO:0051270 55 0.010
immune system process GO:0002376 241 0.010
cellular amino acid metabolic process GO:0006520 7 0.010
regulation of gtp catabolic process GO:0033124 2 0.010
gland development GO:0048732 143 0.010
spliceosomal complex assembly GO:0000245 1 0.010
positive regulation of response to stimulus GO:0048584 80 0.010
lipid storage GO:0019915 1 0.010
mononuclear cell proliferation GO:0032943 1 0.010

tia1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.023
nervous system disease DOID:863 0 0.016