Danio rerio

30 known processes

nfix

nuclear factor I/X

nfix biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
striated muscle tissue development GO:0014706 110 0.153
response to external stimulus GO:0009605 264 0.112
cellular nitrogen compound metabolic process GO:0034641 290 0.095
zinc ion transmembrane transport GO:0071577 1 0.086
cell motility GO:0048870 244 0.062
cellular component movement GO:0006928 335 0.053
regulation of nitrogen compound metabolic process GO:0051171 251 0.052
organic cyclic compound biosynthetic process GO:1901362 223 0.052
vasculature development GO:0001944 278 0.051
maintenance of location GO:0051235 4 0.049
regulation of cellular metabolic process GO:0031323 320 0.049
blood vessel development GO:0001568 246 0.049
response to nutrient GO:0007584 3 0.048
skeletal muscle organ development GO:0060538 78 0.048
positive regulation of transport GO:0051050 2 0.047
homeostatic process GO:0042592 142 0.047
heterocycle metabolic process GO:0046483 290 0.047
response to chemical GO:0042221 320 0.046
transport GO:0006810 220 0.046
nucleic acid templated transcription GO:0097659 181 0.046
heterocycle biosynthetic process GO:0018130 215 0.045
digestive tract morphogenesis GO:0048546 231 0.045
cellular aromatic compound metabolic process GO:0006725 295 0.045
immune system development GO:0002520 191 0.044
aromatic compound biosynthetic process GO:0019438 217 0.044
transcription dna templated GO:0006351 181 0.043
digestive system development GO:0055123 289 0.043
embryo development ending in birth or egg hatching GO:0009792 271 0.043
morphogenesis of an epithelium GO:0002009 333 0.043
aging GO:0007568 2 0.043
cognition GO:0050890 1 0.043
regulation of metabolic process GO:0019222 359 0.041
hemopoiesis GO:0030097 183 0.041
nitrogen compound metabolic process GO:0006807 319 0.041
single organism metabolic process GO:0044710 217 0.041
cellular macromolecule biosynthetic process GO:0034645 224 0.040
locomotion GO:0040011 313 0.040
organic cyclic compound metabolic process GO:1901360 301 0.039
regulation of reproductive process GO:2000241 4 0.039
ion transport GO:0006811 114 0.039
nucleobase containing compound metabolic process GO:0006139 274 0.039
hematopoietic or lymphoid organ development GO:0048534 191 0.039
regulation of biological quality GO:0065008 263 0.038
single organism localization GO:1902578 225 0.037
embryonic organ development GO:0048568 381 0.037
negative regulation of biological process GO:0048519 304 0.037
regulation of rna biosynthetic process GO:2001141 213 0.036
regulation of transcription dna templated GO:0006355 213 0.035
translational initiation GO:0006413 3 0.035
rna metabolic process GO:0016070 219 0.035
muscle cell development GO:0055001 115 0.034
chordate embryonic development GO:0043009 271 0.034
response to stress GO:0006950 263 0.034
tube morphogenesis GO:0035239 349 0.034
regulation of localization GO:0032879 104 0.033
autophagy GO:0006914 4 0.033
regulation of nucleic acid templated transcription GO:1903506 213 0.033
regulation of wound healing GO:0061041 2 0.032
sprouting angiogenesis GO:0002040 53 0.031
cellular nitrogen compound biosynthetic process GO:0044271 218 0.031
cation transmembrane transport GO:0098655 65 0.030
cell projection organization GO:0030030 284 0.030
regulation of rna metabolic process GO:0051252 224 0.030
localization of cell GO:0051674 244 0.029
somitogenesis GO:0001756 87 0.028
blood vessel morphogenesis GO:0048514 216 0.028
cellular macromolecule metabolic process GO:0044260 391 0.027
regulation of autophagy GO:0010506 3 0.027
gene expression GO:0010467 252 0.027
angiogenesis GO:0001525 158 0.027
single organism transport GO:0044765 206 0.027
establishment of localization GO:0051234 244 0.027
skeletal muscle tissue development GO:0007519 67 0.027
generation of neurons GO:0048699 385 0.027
larval development GO:0002164 2 0.027
ion transmembrane transport GO:0034220 91 0.026
brain development GO:0007420 293 0.026
cell part morphogenesis GO:0032990 246 0.026
stem cell maintenance GO:0019827 4 0.026
rna biosynthetic process GO:0032774 181 0.026
regulation of cellular biosynthetic process GO:0031326 245 0.025
nucleic acid metabolic process GO:0090304 244 0.025
digestive tract development GO:0048565 265 0.025
production of molecular mediator of immune response GO:0002440 2 0.025
regulation of primary metabolic process GO:0080090 311 0.025
muscle cell differentiation GO:0042692 139 0.025
gastrulation GO:0007369 208 0.025
regulation of biosynthetic process GO:0009889 250 0.024
immune system process GO:0002376 241 0.024
cell migration GO:0016477 237 0.024
response to vitamin GO:0033273 3 0.024
positive regulation of cell cycle GO:0045787 3 0.024
transmembrane transport GO:0055085 120 0.023
response to abiotic stimulus GO:0009628 122 0.023
head development GO:0060322 303 0.023
glucose homeostasis GO:0042593 1 0.023
muscle structure development GO:0061061 196 0.023
regulation of gene expression GO:0010468 265 0.022
regulation of microtubule cytoskeleton organization GO:0070507 3 0.022
cation transport GO:0006812 81 0.022
regulation of macromolecule metabolic process GO:0060255 317 0.022
metal ion transport GO:0030001 58 0.021
response to other organism GO:0051707 97 0.021
development of primary female sexual characteristics GO:0046545 4 0.021
cellular component biogenesis GO:0044085 178 0.021
cellular response to external stimulus GO:0071496 2 0.020
determination of bilateral symmetry GO:0009855 204 0.020
response to transition metal nanoparticle GO:1990267 28 0.020
signal transduction GO:0007165 455 0.020
muscle tissue development GO:0060537 110 0.020
mitochondrion organization GO:0007005 4 0.020
regionalization GO:0003002 274 0.020
regulation of metal ion transport GO:0010959 4 0.020
segmentation GO:0035282 97 0.020
regulation of response to stimulus GO:0048583 269 0.020
regulation of blood vessel size GO:0050880 2 0.019
regulation of organelle assembly GO:1902115 4 0.019
sequestering of metal ion GO:0051238 3 0.019
system process GO:0003008 185 0.019
striated muscle cell differentiation GO:0051146 129 0.019
adherens junction organization GO:0034332 4 0.019
regulation of cellular ketone metabolic process GO:0010565 7 0.019
regulation of production of molecular mediator of immune response GO:0002700 1 0.019
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.019
negative regulation of cellular process GO:0048523 283 0.019
somite development GO:0061053 96 0.019
regulation of signal transduction GO:0009966 225 0.019
embryonic organ morphogenesis GO:0048562 274 0.018
cellular component assembly GO:0022607 170 0.018
regulation of establishment of protein localization GO:0070201 4 0.018
female sex differentiation GO:0046660 4 0.018
chemical homeostasis GO:0048878 49 0.018
ovulation cycle process GO:0022602 2 0.018
eye development GO:0001654 277 0.018
regulation of calcium ion transport GO:0051924 2 0.018
transcription from rna polymerase ii promoter GO:0006366 80 0.018
ameboidal type cell migration GO:0001667 143 0.018
response to external biotic stimulus GO:0043207 97 0.018
ovulation cycle GO:0042698 2 0.018
regulation of cell communication GO:0010646 232 0.017
meiotic nuclear division GO:0007126 4 0.017
biosynthetic process GO:0009058 294 0.017
amine metabolic process GO:0009308 2 0.017
sensory organ morphogenesis GO:0090596 200 0.017
central nervous system development GO:0007417 387 0.017
sensory organ development GO:0007423 393 0.017
carbohydrate biosynthetic process GO:0016051 1 0.017
inorganic cation transmembrane transport GO:0098662 50 0.017
cell morphogenesis involved in differentiation GO:0000904 195 0.017
ribosomal small subunit biogenesis GO:0042274 2 0.017
negative regulation of gene expression GO:0010629 65 0.017
regulation of cellular amine metabolic process GO:0033238 0 0.017
stem cell differentiation GO:0048863 117 0.017
female gonad development GO:0008585 4 0.017
cellular response to extracellular stimulus GO:0031668 2 0.017
meiotic cell cycle process GO:1903046 3 0.016
negative regulation of protein phosphorylation GO:0001933 4 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
regulation of cell activation GO:0050865 1 0.016
multicellular organism growth GO:0035264 4 0.016
regulation of protein transport GO:0051223 3 0.016
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.016
adult behavior GO:0030534 2 0.016
eye morphogenesis GO:0048592 144 0.016
microtubule organizing center organization GO:0031023 1 0.016
single organism organelle organization GO:1902589 199 0.016
peptide metabolic process GO:0006518 1 0.016
positive regulation of cell activation GO:0050867 1 0.016
positive regulation of epithelial cell differentiation GO:0030858 2 0.016
phagocytosis GO:0006909 3 0.016
cell surface receptor signaling pathway GO:0007166 325 0.016
regulation of signaling GO:0023051 235 0.016
specification of symmetry GO:0009799 204 0.015
carbohydrate homeostasis GO:0033500 1 0.015
regulation of translational initiation GO:0006446 1 0.015
heart development GO:0007507 313 0.015
determination of heart left right asymmetry GO:0061371 117 0.015
macromolecule biosynthetic process GO:0009059 227 0.015
neuromast development GO:0048884 46 0.015
regulation of cytoplasmic transport GO:1903649 4 0.015
nitric oxide metabolic process GO:0046209 2 0.015
regulation of mrna processing GO:0050684 3 0.015
cellular response to chemical stimulus GO:0070887 157 0.015
regulation of blood pressure GO:0008217 1 0.015
cell substrate adhesion GO:0031589 4 0.015
nucleobase containing compound biosynthetic process GO:0034654 205 0.015
regulation of multicellular organism growth GO:0040014 4 0.015
cellular response to nutrient levels GO:0031669 2 0.014
regulation of response to biotic stimulus GO:0002831 2 0.014
neuron development GO:0048666 262 0.014
striated muscle cell development GO:0055002 108 0.014
negative regulation of transcription dna templated GO:0045892 45 0.014
notochord development GO:0030903 54 0.014
retina morphogenesis in camera type eye GO:0060042 79 0.014
cellular component morphogenesis GO:0032989 336 0.014
b cell activation GO:0042113 2 0.014
transition metal ion transport GO:0000041 6 0.014
regulation of multicellular organismal process GO:0051239 277 0.014
peptide transport GO:0015833 1 0.014
anterior posterior pattern specification GO:0009952 152 0.014
negative regulation of protein kinase activity GO:0006469 4 0.014
regulation of developmental process GO:0050793 247 0.014
positive regulation of secretion GO:0051047 1 0.014
cellular ketone metabolic process GO:0042180 11 0.014
determination of left right symmetry GO:0007368 179 0.014
regulation of blood coagulation GO:0030193 1 0.014
muscle organ development GO:0007517 101 0.014
mesenchyme development GO:0060485 127 0.014
nucleocytoplasmic transport GO:0006913 4 0.014
regulation of tube size GO:0035150 2 0.014
cell morphogenesis GO:0000902 289 0.014
organelle organization GO:0006996 227 0.014
lateral line development GO:0048882 66 0.014
positive regulation of secretion by cell GO:1903532 1 0.013
gtp catabolic process GO:0006184 2 0.013
chemosensory behavior GO:0007635 1 0.013
multi organism process GO:0051704 134 0.013
positive regulation of cellular process GO:0048522 201 0.013
lipid storage GO:0019915 1 0.013
negative regulation of developmental process GO:0051093 65 0.013
notochord cell differentiation GO:0060034 18 0.013
establishment of protein localization to organelle GO:0072594 4 0.013
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.013
organic substance biosynthetic process GO:1901576 289 0.013
response to light stimulus GO:0009416 46 0.013
centrosome organization GO:0051297 1 0.013
retina development in camera type eye GO:0060041 146 0.013
regulation of protein binding GO:0043393 3 0.013
i kappab kinase nf kappab signaling GO:0007249 4 0.012
cellular response to starvation GO:0009267 1 0.012
nuclear export GO:0051168 1 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.012
regulation of cytokine production GO:0001817 3 0.012
response to hexose GO:0009746 3 0.012
sensory system development GO:0048880 76 0.012
growth GO:0040007 174 0.012
regulation of binding GO:0051098 3 0.012
positive regulation of translation GO:0045727 1 0.012
gtp metabolic process GO:0046039 4 0.012
cell projection morphogenesis GO:0048858 244 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.012
protein homooligomerization GO:0051260 3 0.012
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.012
eye photoreceptor cell development GO:0042462 30 0.012
cellular amine metabolic process GO:0044106 2 0.012
spermatid differentiation GO:0048515 2 0.011
regulation of endothelial cell proliferation GO:0001936 1 0.011
positive regulation of biological process GO:0048518 253 0.011
positive regulation of catabolic process GO:0009896 4 0.011
regulation of multicellular organismal development GO:2000026 223 0.011
mononuclear cell proliferation GO:0032943 1 0.011
response to metal ion GO:0010038 34 0.011
cell migration involved in gastrulation GO:0042074 79 0.011
cellular biosynthetic process GO:0044249 286 0.011
guanosine containing compound catabolic process GO:1901069 2 0.011
response to drug GO:0042493 3 0.011
organelle assembly GO:0070925 110 0.011
negative regulation of rna biosynthetic process GO:1902679 45 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.011
post embryonic morphogenesis GO:0009886 4 0.011
regulation of cellular protein catabolic process GO:1903362 1 0.011
mesoderm development GO:0007498 88 0.011
epithelial tube morphogenesis GO:0060562 148 0.011
negative regulation of kinase activity GO:0033673 4 0.011
protein metabolic process GO:0019538 183 0.011
guanosine containing compound metabolic process GO:1901068 4 0.011
neuron differentiation GO:0030182 353 0.011
neuronal action potential GO:0019228 18 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
regulation of reactive oxygen species metabolic process GO:2000377 2 0.011
muscle fiber development GO:0048747 52 0.011
b cell differentiation GO:0030183 1 0.011
morphogenesis of an epithelial sheet GO:0002011 49 0.011
oxoacid metabolic process GO:0043436 31 0.011
regulation of nucleotide catabolic process GO:0030811 2 0.011
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.011
positive regulation of cytokine production GO:0001819 2 0.011
cellular carbohydrate metabolic process GO:0044262 4 0.010
kidney development GO:0001822 92 0.010
behavior GO:0007610 74 0.010
cell proliferation GO:0008283 80 0.010
cellular component assembly involved in morphogenesis GO:0010927 107 0.010
secondary metabolic process GO:0019748 3 0.010
positive regulation of gene expression GO:0010628 71 0.010
protein localization to nucleus GO:0034504 3 0.010
hormone transport GO:0009914 2 0.010
nuclear transport GO:0051169 4 0.010
g1 s transition of mitotic cell cycle GO:0000082 1 0.010
regulation of transporter activity GO:0032409 2 0.010
organonitrogen compound metabolic process GO:1901564 74 0.010

nfix disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.101
musculoskeletal system disease DOID:17 0 0.048
immune system disease DOID:2914 0 0.033
hematopoietic system disease DOID:74 0 0.033
bone marrow disease DOID:4961 0 0.032
congenital hypoplastic anemia DOID:1342 0 0.031
aplastic anemia DOID:12449 0 0.031
fanconi s anemia DOID:13636 0 0.031
anemia DOID:2355 0 0.031
nervous system disease DOID:863 0 0.018
disease of metabolism DOID:0014667 0 0.014
connective tissue disease DOID:65 0 0.013
bone disease DOID:0080001 0 0.012
muscular disease DOID:0080000 0 0.011