Danio rerio

33 known processes

si:dkeyp-27b10.2

si:dkeyp-27b10.2

si:dkeyp-27b10.2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
sensory organ development GO:0007423 393 0.197
embryonic organ morphogenesis GO:0048562 274 0.169
embryonic organ development GO:0048568 381 0.124
head development GO:0060322 303 0.107
sensory organ morphogenesis GO:0090596 200 0.106
larval development GO:0002164 2 0.069
ear development GO:0043583 127 0.065
regulation of macromolecule metabolic process GO:0060255 317 0.051
nucleic acid templated transcription GO:0097659 181 0.048
cellular macromolecule metabolic process GO:0044260 391 0.047
regulation of biosynthetic process GO:0009889 250 0.046
regionalization GO:0003002 274 0.043
aging GO:0007568 2 0.042
organic substance biosynthetic process GO:1901576 289 0.040
neuron differentiation GO:0030182 353 0.040
regulation of rna biosynthetic process GO:2001141 213 0.038
neuron neuron synaptic transmission GO:0007270 1 0.038
brain development GO:0007420 293 0.037
phagocytosis GO:0006909 3 0.036
generation of neurons GO:0048699 385 0.036
stem cell maintenance GO:0019827 4 0.035
neurotransmitter transport GO:0006836 2 0.035
response to other organism GO:0051707 97 0.035
response to carbohydrate GO:0009743 3 0.034
positive regulation of transport GO:0051050 2 0.034
cellular nitrogen compound biosynthetic process GO:0044271 218 0.034
regulation of nitrogen compound metabolic process GO:0051171 251 0.033
cell migration GO:0016477 237 0.033
cell projection organization GO:0030030 284 0.033
cell fate commitment GO:0045165 99 0.032
organic cyclic compound biosynthetic process GO:1901362 223 0.032
macromolecule biosynthetic process GO:0009059 227 0.032
blood vessel development GO:0001568 246 0.032
camera type eye development GO:0043010 222 0.031
regulation of transcription dna templated GO:0006355 213 0.031
heterocycle biosynthetic process GO:0018130 215 0.031
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.031
inner ear development GO:0048839 126 0.030
cell projection morphogenesis GO:0048858 244 0.030
regulation of cellular biosynthetic process GO:0031326 245 0.030
hormone transport GO:0009914 2 0.030
nucleobase containing compound biosynthetic process GO:0034654 205 0.029
chemosensory behavior GO:0007635 1 0.029
regulation of macromolecule biosynthetic process GO:0010556 225 0.029
cell part morphogenesis GO:0032990 246 0.029
regulation of multicellular organismal process GO:0051239 277 0.028
neurotransmitter secretion GO:0007269 2 0.028
production of molecular mediator of immune response GO:0002440 2 0.028
gene expression GO:0010467 252 0.028
regulation of synaptic plasticity GO:0048167 1 0.028
aromatic compound biosynthetic process GO:0019438 217 0.027
rna biosynthetic process GO:0032774 181 0.027
cellular component morphogenesis GO:0032989 336 0.027
nitrogen compound metabolic process GO:0006807 319 0.027
multicellular organism growth GO:0035264 4 0.027
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.027
neuron development GO:0048666 262 0.027
cell morphogenesis GO:0000902 289 0.027
cellular nitrogen compound metabolic process GO:0034641 290 0.027
cellular amine metabolic process GO:0044106 2 0.026
eye development GO:0001654 277 0.026
biosynthetic process GO:0009058 294 0.026
transcription from rna polymerase ii promoter GO:0006366 80 0.026
regulation of metabolic process GO:0019222 359 0.026
hormone secretion GO:0046879 2 0.025
cognition GO:0050890 1 0.025
regulation of cellular amine metabolic process GO:0033238 0 0.025
transcription dna templated GO:0006351 181 0.025
nucleic acid metabolic process GO:0090304 244 0.024
response to glucose GO:0009749 3 0.024
meiotic cell cycle process GO:1903046 3 0.024
rna metabolic process GO:0016070 219 0.024
regulation of gene expression GO:0010468 265 0.024
cellular biosynthetic process GO:0044249 286 0.024
morphogenesis of an epithelium GO:0002009 333 0.024
regulation of cellular metabolic process GO:0031323 320 0.024
positive regulation of cell cycle GO:0045787 3 0.024
signal transduction GO:0007165 455 0.024
chordate embryonic development GO:0043009 271 0.024
response to biotic stimulus GO:0009607 97 0.024
female gonad development GO:0008585 4 0.024
system process GO:0003008 185 0.023
locomotion GO:0040011 313 0.023
positive regulation of catabolic process GO:0009896 4 0.023
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.023
negative regulation of cellular process GO:0048523 283 0.023
negative regulation of biological process GO:0048519 304 0.023
vasculature development GO:0001944 278 0.023
transport GO:0006810 220 0.023
lateral line system development GO:0048925 76 0.023
muscle structure development GO:0061061 196 0.022
immune system process GO:0002376 241 0.022
maternal determination of anterior posterior axis embryo GO:0008358 4 0.022
response to monosaccharide GO:0034284 3 0.022
central nervous system development GO:0007417 387 0.022
single organism organelle organization GO:1902589 199 0.022
organic cyclic compound metabolic process GO:1901360 301 0.022
regulation of metal ion transport GO:0010959 4 0.022
regulation of signaling GO:0023051 235 0.022
ear morphogenesis GO:0042471 64 0.022
sensory system development GO:0048880 76 0.021
nucleobase containing compound metabolic process GO:0006139 274 0.021
tube morphogenesis GO:0035239 349 0.021
adult behavior GO:0030534 2 0.021
cellular aromatic compound metabolic process GO:0006725 295 0.021
digestive system development GO:0055123 289 0.021
negative regulation of reproductive process GO:2000242 3 0.021
reflex GO:0060004 2 0.020
retina development in camera type eye GO:0060041 146 0.020
regulation of synapse organization GO:0050807 3 0.020
regulation of nucleic acid templated transcription GO:1903506 213 0.020
cell motility GO:0048870 244 0.020
cellular component movement GO:0006928 335 0.020
actin filament polymerization GO:0030041 2 0.020
single organism metabolic process GO:0044710 217 0.020
regulation of synapse assembly GO:0051963 3 0.020
regulation of ion transmembrane transporter activity GO:0032412 2 0.020
cell fate specification GO:0001708 68 0.020
leukocyte proliferation GO:0070661 1 0.020
regulation of primary metabolic process GO:0080090 311 0.020
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.020
cellular amide metabolic process GO:0043603 4 0.020
compound eye development GO:0048749 2 0.020
regulation of rna metabolic process GO:0051252 224 0.020
mononuclear cell proliferation GO:0032943 1 0.020
response to external stimulus GO:0009605 264 0.019
cellular macromolecule biosynthetic process GO:0034645 224 0.019
regulation of hormone secretion GO:0046883 2 0.019
embryonic skeletal system development GO:0048706 97 0.019
regulation of production of molecular mediator of immune response GO:0002700 1 0.019
carbohydrate homeostasis GO:0033500 1 0.019
negative regulation of protein kinase activity GO:0006469 4 0.019
internal peptidyl lysine acetylation GO:0018393 2 0.019
lateral line ganglion development GO:0048890 2 0.018
heterocycle metabolic process GO:0046483 290 0.018
maintenance of location GO:0051235 4 0.018
amine metabolic process GO:0009308 2 0.018
response to hexose GO:0009746 3 0.018
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
regulation of establishment of protein localization GO:0070201 4 0.018
regulation of protein transport GO:0051223 3 0.018
embryonic skeletal system morphogenesis GO:0048704 93 0.018
regulation of biological quality GO:0065008 263 0.018
peptide transport GO:0015833 1 0.018
regulation of multicellular organismal development GO:2000026 223 0.018
response to amine GO:0014075 1 0.017
positive regulation of cellular catabolic process GO:0031331 3 0.017
amino acid transport GO:0006865 2 0.017
olfactory lobe development GO:0021988 4 0.017
gastrulation GO:0007369 208 0.017
internal protein amino acid acetylation GO:0006475 2 0.017
protein acylation GO:0043543 3 0.017
peptidyl lysine acetylation GO:0018394 2 0.017
regulation of binding GO:0051098 3 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.017
digestive tract development GO:0048565 265 0.017
endoderm development GO:0007492 49 0.017
regulation of reactive oxygen species metabolic process GO:2000377 2 0.017
striated muscle cell development GO:0055002 108 0.017
synaptic target recognition GO:0008039 1 0.017
heart development GO:0007507 313 0.017
regulation of cytokine production GO:0001817 3 0.017
regulation of neuronal synaptic plasticity GO:0048168 1 0.017
positive regulation of cytokine production GO:0001819 2 0.017
regulation of cell activation GO:0050865 1 0.017
regulation of response to stimulus GO:0048583 269 0.017
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.017
regulation of endocrine process GO:0044060 2 0.016
immune system development GO:0002520 191 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.016
cell morphogenesis involved in differentiation GO:0000904 195 0.016
regulation of protein catabolic process GO:0042176 1 0.016
female sex differentiation GO:0046660 4 0.016
neuron projection morphogenesis GO:0048812 161 0.016
negative regulation of secretion GO:0051048 2 0.016
single organism localization GO:1902578 225 0.016
regulation of transporter activity GO:0032409 2 0.016
organic acid metabolic process GO:0006082 31 0.016
retina morphogenesis in camera type eye GO:0060042 79 0.016
regulation of response to biotic stimulus GO:0002831 2 0.016
response to chemical GO:0042221 320 0.016
embryo development ending in birth or egg hatching GO:0009792 271 0.016
determination of bilateral symmetry GO:0009855 204 0.015
transmembrane transport GO:0055085 120 0.015
regulation of reproductive process GO:2000241 4 0.015
golgi vesicle transport GO:0048193 3 0.015
ion transmembrane transport GO:0034220 91 0.015
gland development GO:0048732 143 0.015
cytokinesis GO:0000910 3 0.015
organonitrogen compound metabolic process GO:1901564 74 0.015
regulation of multicellular organism growth GO:0040014 4 0.015
synaptic vesicle localization GO:0097479 1 0.015
renal system development GO:0072001 94 0.015
guanosine containing compound metabolic process GO:1901068 4 0.014
response to amphetamine GO:0001975 1 0.014
muscle tissue development GO:0060537 110 0.014
cellular response to molecule of bacterial origin GO:0071219 3 0.014
modification dependent macromolecule catabolic process GO:0043632 3 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
neuromast development GO:0048884 46 0.014
protein secretion GO:0009306 1 0.014
actin polymerization or depolymerization GO:0008154 2 0.014
negative regulation of histone modification GO:0031057 1 0.014
specification of symmetry GO:0009799 204 0.014
regulation of protein complex assembly GO:0043254 3 0.014
otic placode formation GO:0043049 23 0.014
g protein coupled receptor signaling pathway GO:0007186 74 0.014
neuromuscular process controlling balance GO:0050885 3 0.014
carbohydrate biosynthetic process GO:0016051 1 0.014
regulation of transmembrane transporter activity GO:0022898 2 0.014
cellular protein modification process GO:0006464 100 0.014
response to stress GO:0006950 263 0.014
positive regulation of cytoskeleton organization GO:0051495 3 0.014
regulation of cell communication GO:0010646 232 0.014
phagocytosis engulfment GO:0006911 1 0.014
regulation of dendrite development GO:0050773 3 0.014
protein acetylation GO:0006473 2 0.014
response to superoxide GO:0000303 2 0.014
protein metabolic process GO:0019538 183 0.014
negative regulation of chromosome organization GO:2001251 1 0.014
negative regulation of kinase activity GO:0033673 4 0.013
cellular carbohydrate metabolic process GO:0044262 4 0.013
camera type eye morphogenesis GO:0048593 108 0.013
positive regulation of reproductive process GO:2000243 2 0.013
regulation of developmental process GO:0050793 247 0.013
localization of cell GO:0051674 244 0.013
response to external biotic stimulus GO:0043207 97 0.013
protein modification process GO:0036211 100 0.013
regulation of neurotransmitter transport GO:0051588 1 0.013
peptide metabolic process GO:0006518 1 0.013
positive regulation of cell killing GO:0031343 2 0.013
negative regulation of protein localization to nucleus GO:1900181 2 0.013
regulation of cellular ketone metabolic process GO:0010565 7 0.013
nuclear transport GO:0051169 4 0.013
protein localization to plasma membrane GO:0072659 1 0.013
modification dependent protein catabolic process GO:0019941 3 0.013
eye morphogenesis GO:0048592 144 0.013
lipid storage GO:0019915 1 0.013
lymphocyte proliferation GO:0046651 1 0.013
response to bacterium GO:0009617 58 0.013
glucose homeostasis GO:0042593 1 0.013
adherens junction organization GO:0034332 4 0.013
ribonucleoside monophosphate catabolic process GO:0009158 4 0.013
hemopoiesis GO:0030097 183 0.013
dorsal ventral pattern formation GO:0009953 125 0.013
negative regulation of mapk cascade GO:0043409 4 0.013
cellular response to biotic stimulus GO:0071216 3 0.013
small molecule metabolic process GO:0044281 77 0.013
hematopoietic or lymphoid organ development GO:0048534 191 0.013
hatching gland development GO:0048785 3 0.013
regulation of neurotransmitter secretion GO:0046928 1 0.013
establishment of protein localization to organelle GO:0072594 4 0.013
negative regulation of protein phosphorylation GO:0001933 4 0.013
muscle organ development GO:0007517 101 0.013
negative regulation of secretion by cell GO:1903531 2 0.013
segmentation GO:0035282 97 0.013
olfactory bulb development GO:0021772 4 0.013
establishment of localization GO:0051234 244 0.013
synaptic growth at neuromuscular junction GO:0051124 2 0.013
cellular protein catabolic process GO:0044257 4 0.013
convergent extension involved in gastrulation GO:0060027 71 0.013
regulation of protein polymerization GO:0032271 2 0.012
vestibular receptor cell development GO:0060118 3 0.012
lipid catabolic process GO:0016042 4 0.012
establishment of synaptic vesicle localization GO:0097480 1 0.012
oxoacid metabolic process GO:0043436 31 0.012
mesenchyme development GO:0060485 127 0.012
positive regulation of blood circulation GO:1903524 2 0.012
epidermis development GO:0008544 48 0.012
synaptic vesicle transport GO:0048489 1 0.012
skeletal system development GO:0001501 181 0.012
regulation of sodium ion transport GO:0002028 2 0.012
muscle cell development GO:0055001 115 0.012
cytoplasm organization GO:0007028 4 0.012
neurological system process GO:0050877 62 0.012
cranial ganglion development GO:0061550 3 0.012
homeostatic process GO:0042592 142 0.012
outflow tract morphogenesis GO:0003151 1 0.012
centrosome organization GO:0051297 1 0.012
oocyte anterior posterior axis specification GO:0007314 4 0.012
water homeostasis GO:0030104 4 0.012
dicarboxylic acid transport GO:0006835 1 0.012
regulation of circadian rhythm GO:0042752 4 0.012
proteasomal protein catabolic process GO:0010498 2 0.012
stem cell development GO:0048864 82 0.012
cell surface receptor signaling pathway GO:0007166 325 0.012
transmission of nerve impulse GO:0019226 19 0.012
stem cell differentiation GO:0048863 117 0.012
regulation of inflammatory response GO:0050727 2 0.012
cellular response to lipopolysaccharide GO:0071222 3 0.012
regulation of meiotic cell cycle GO:0051445 1 0.012
negative regulation of protein transport GO:0051224 3 0.011
multi organism process GO:0051704 134 0.011
positive regulation of leukocyte mediated cytotoxicity GO:0001912 1 0.011
lateral line development GO:0048882 66 0.011
protein localization to nucleus GO:0034504 3 0.011
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.011
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.011
ubiquitin dependent protein catabolic process GO:0006511 3 0.011
skeletal system morphogenesis GO:0048705 102 0.011
meiotic chromosome segregation GO:0045132 3 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
positive regulation of immune effector process GO:0002699 3 0.011
positive regulation of cell activation GO:0050867 1 0.011
nucleoside monophosphate catabolic process GO:0009125 4 0.011
regulation of neuron differentiation GO:0045664 56 0.011
inorganic anion transport GO:0015698 25 0.011
mesenchymal cell development GO:0014031 78 0.011
cellular component disassembly GO:0022411 1 0.011
epithelial cell differentiation GO:0030855 116 0.011
regulation of signal transduction GO:0009966 225 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.011
ribose phosphate biosynthetic process GO:0046390 20 0.011
myelin assembly GO:0032288 1 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.011
cellular response to external stimulus GO:0071496 2 0.011
otic vesicle morphogenesis GO:0071600 34 0.011
positive regulation of histone modification GO:0031058 1 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.011
ameboidal type cell migration GO:0001667 143 0.011
negative regulation of metabolic process GO:0009892 86 0.011
multicellular organismal response to stress GO:0033555 2 0.011
response to organic substance GO:0010033 153 0.011
cilium morphogenesis GO:0060271 85 0.011
carbohydrate derivative biosynthetic process GO:1901137 43 0.011
heart morphogenesis GO:0003007 156 0.011
lens fiber cell development GO:0070307 3 0.011
b cell activation GO:0042113 2 0.011
ectodermal placode morphogenesis GO:0071697 32 0.011
negative regulation of macromolecule metabolic process GO:0010605 76 0.011
nuclear import GO:0051170 3 0.011
fin development GO:0033333 77 0.011
positive regulation of map kinase activity GO:0043406 3 0.011
regulation of calcium ion transport GO:0051924 2 0.010
organelle organization GO:0006996 227 0.010
positive regulation of nucleic acid templated transcription GO:1903508 57 0.010
positive regulation of protein polymerization GO:0032273 2 0.010
cytoskeleton organization GO:0007010 96 0.010
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.010
negative regulation of nucleic acid templated transcription GO:1903507 45 0.010
small molecule catabolic process GO:0044282 3 0.010
regulation of tube size GO:0035150 2 0.010
synaptic vesicle endocytosis GO:0048488 1 0.010
leukocyte mediated cytotoxicity GO:0001909 1 0.010
negative regulation of dna metabolic process GO:0051053 4 0.010
cilium organization GO:0044782 71 0.010
gtp catabolic process GO:0006184 2 0.010
development of primary female sexual characteristics GO:0046545 4 0.010
regulation of cell development GO:0060284 100 0.010
response to drug GO:0042493 3 0.010
autophagy GO:0006914 4 0.010
pectoral fin development GO:0033339 50 0.010
positive regulation of secretion GO:0051047 1 0.010
axon development GO:0061564 166 0.010
regulation of neural precursor cell proliferation GO:2000177 3 0.010
digestive tract morphogenesis GO:0048546 231 0.010
endocrine hormone secretion GO:0060986 2 0.010
post embryonic organ development GO:0048569 4 0.010
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.010
protein stabilization GO:0050821 2 0.010
atp catabolic process GO:0006200 4 0.010
positive regulation of biological process GO:0048518 253 0.010

si:dkeyp-27b10.2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.038
musculoskeletal system disease DOID:17 0 0.027
cardiovascular system disease DOID:1287 0 0.015
disease of cellular proliferation DOID:14566 0 0.012
nervous system disease DOID:863 0 0.011
muscular disease DOID:0080000 0 0.011
cancer DOID:162 0 0.011
organ system cancer DOID:0050686 0 0.011