Danio rerio

10 known processes

flnca

filamin C, gamma a (actin binding protein 280)

flnca biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
muscle cell differentiation GO:0042692 139 0.183
negative regulation of biological process GO:0048519 304 0.129
maintenance of location GO:0051235 4 0.115
cellular nitrogen compound biosynthetic process GO:0044271 218 0.113
cognition GO:0050890 1 0.094
cellular nitrogen compound metabolic process GO:0034641 290 0.087
positive regulation of transport GO:0051050 2 0.082
regionalization GO:0003002 274 0.080
larval development GO:0002164 2 0.079
regulation of nitrogen compound metabolic process GO:0051171 251 0.078
skeletal myofibril assembly GO:0014866 7 0.075
aromatic compound biosynthetic process GO:0019438 217 0.072
nitrogen compound metabolic process GO:0006807 319 0.065
signal transduction GO:0007165 455 0.064
cellular component movement GO:0006928 335 0.062
transcription from rna polymerase ii promoter GO:0006366 80 0.058
nucleobase containing compound metabolic process GO:0006139 274 0.058
actin filament based movement GO:0030048 1 0.058
multicellular organism growth GO:0035264 4 0.057
regulation of macromolecule metabolic process GO:0060255 317 0.056
muscle cell development GO:0055001 115 0.056
aging GO:0007568 2 0.055
cellular aromatic compound metabolic process GO:0006725 295 0.054
chemosensory behavior GO:0007635 1 0.052
cellular amine metabolic process GO:0044106 2 0.052
cell surface receptor signaling pathway GO:0007166 325 0.051
biosynthetic process GO:0009058 294 0.051
regulation of cellular metabolic process GO:0031323 320 0.050
regulation of nucleic acid templated transcription GO:1903506 213 0.050
organic cyclic compound metabolic process GO:1901360 301 0.049
rna biosynthetic process GO:0032774 181 0.048
cellular biosynthetic process GO:0044249 286 0.047
cellular component morphogenesis GO:0032989 336 0.046
regulation of metabolic process GO:0019222 359 0.046
regulation of signal transduction GO:0009966 225 0.045
regulation of muscle contraction GO:0006937 3 0.044
regulation of biosynthetic process GO:0009889 250 0.043
regulation of primary metabolic process GO:0080090 311 0.043
cell projection morphogenesis GO:0048858 244 0.043
response to drug GO:0042493 3 0.043
cellular macromolecule metabolic process GO:0044260 391 0.041
nucleic acid templated transcription GO:0097659 181 0.039
regulation of metal ion transport GO:0010959 4 0.039
amine metabolic process GO:0009308 2 0.038
voluntary skeletal muscle contraction GO:0003010 4 0.038
regulation of cellular biosynthetic process GO:0031326 245 0.037
heterocycle metabolic process GO:0046483 290 0.036
sensory perception of chemical stimulus GO:0007606 3 0.035
regulation of cell communication GO:0010646 232 0.035
neuroblast differentiation GO:0014016 1 0.035
mitochondrion organization GO:0007005 4 0.035
regulation of cellular ketone metabolic process GO:0010565 7 0.035
skeletal system development GO:0001501 181 0.035
negative regulation of cellular process GO:0048523 283 0.034
regulation of ion transmembrane transporter activity GO:0032412 2 0.034
purine nucleoside monophosphate catabolic process GO:0009128 4 0.034
regulation of rna metabolic process GO:0051252 224 0.033
anterior posterior pattern specification GO:0009952 152 0.033
heart development GO:0007507 313 0.033
regulation of protein complex assembly GO:0043254 3 0.033
response to alkaloid GO:0043279 2 0.032
macromolecular complex disassembly GO:0032984 1 0.032
regulation of multicellular organism growth GO:0040014 4 0.032
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.032
regulation of transmembrane transporter activity GO:0022898 2 0.031
cell cycle GO:0007049 93 0.031
nucleoside monophosphate catabolic process GO:0009125 4 0.031
response to chemical GO:0042221 320 0.030
cytokinesis GO:0000910 3 0.030
myotube differentiation GO:0014902 45 0.030
cell migration GO:0016477 237 0.030
neuron development GO:0048666 262 0.030
cell projection organization GO:0030030 284 0.030
phagocytosis GO:0006909 3 0.030
outflow tract morphogenesis GO:0003151 1 0.029
single organism membrane fusion GO:0044801 2 0.029
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.029
regulation of biological quality GO:0065008 263 0.029
digestive system development GO:0055123 289 0.029
cellular response to extracellular stimulus GO:0031668 2 0.029
positive regulation of cellular catabolic process GO:0031331 3 0.029
wnt signaling pathway GO:0016055 80 0.028
death GO:0016265 121 0.028
regulation of blood pressure GO:0008217 1 0.028
regulation of cell activation GO:0050865 1 0.028
positive regulation of cell cycle GO:0045787 3 0.028
generation of neurons GO:0048699 385 0.027
regulation of cellular amine metabolic process GO:0033238 0 0.027
establishment of protein localization to organelle GO:0072594 4 0.027
muscle structure development GO:0061061 196 0.027
blood circulation GO:0008015 87 0.027
neuron projection morphogenesis GO:0048812 161 0.027
homeostatic process GO:0042592 142 0.027
regulation of gene expression GO:0010468 265 0.026
organonitrogen compound metabolic process GO:1901564 74 0.026
cellular response to external stimulus GO:0071496 2 0.026
extrinsic apoptotic signaling pathway GO:0097191 3 0.026
positive regulation of cellular metabolic process GO:0031325 94 0.026
cytoskeleton dependent cytokinesis GO:0061640 3 0.026
cellular response to nutrient levels GO:0031669 2 0.026
heterocycle biosynthetic process GO:0018130 215 0.025
tube morphogenesis GO:0035239 349 0.025
small molecule metabolic process GO:0044281 77 0.025
rna metabolic process GO:0016070 219 0.025
organic substance biosynthetic process GO:1901576 289 0.025
b cell activation GO:0042113 2 0.025
lipid homeostasis GO:0055088 3 0.025
nucleobase containing compound biosynthetic process GO:0034654 205 0.025
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.024
actin polymerization or depolymerization GO:0008154 2 0.024
cell motility GO:0048870 244 0.024
macromolecule biosynthetic process GO:0009059 227 0.024
hematopoietic or lymphoid organ development GO:0048534 191 0.024
striated muscle cell development GO:0055002 108 0.024
regulation of signaling GO:0023051 235 0.024
organic cyclic compound biosynthetic process GO:1901362 223 0.024
positive regulation of camp biosynthetic process GO:0030819 2 0.024
immune system development GO:0002520 191 0.024
axon development GO:0061564 166 0.024
cellular response to starvation GO:0009267 1 0.023
vasculature development GO:0001944 278 0.023
regulation of organ growth GO:0046620 3 0.023
developmental programmed cell death GO:0010623 4 0.023
regulation of localization GO:0032879 104 0.023
positive regulation of cytoskeleton organization GO:0051495 3 0.023
lipid storage GO:0019915 1 0.023
regulation of rna biosynthetic process GO:2001141 213 0.022
chemotaxis GO:0006935 104 0.022
cellular ketone metabolic process GO:0042180 11 0.022
ventricular cardiac muscle tissue development GO:0003229 3 0.022
muscle organ development GO:0007517 101 0.022
epidermal cell fate specification GO:0009957 4 0.021
gtp catabolic process GO:0006184 2 0.021
regulation of binding GO:0051098 3 0.021
locomotion GO:0040011 313 0.021
response to external stimulus GO:0009605 264 0.021
cellular macromolecule biosynthetic process GO:0034645 224 0.021
regulation of macromolecule biosynthetic process GO:0010556 225 0.021
meiotic nuclear division GO:0007126 4 0.021
single organism localization GO:1902578 225 0.021
apoptotic process involved in morphogenesis GO:0060561 2 0.020
positive regulation of biosynthetic process GO:0009891 68 0.020
regulation of transcription dna templated GO:0006355 213 0.020
guanosine containing compound catabolic process GO:1901069 2 0.020
developmental growth involved in morphogenesis GO:0060560 86 0.020
cartilage development GO:0051216 96 0.020
phagocytosis engulfment GO:0006911 1 0.020
skeletal muscle thin filament assembly GO:0030240 4 0.020
negative regulation of sequestering of calcium ion GO:0051283 4 0.020
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 22 0.020
meiotic chromosome segregation GO:0045132 3 0.020
cell death GO:0008219 121 0.019
embryonic organ development GO:0048568 381 0.019
regulation of nucleoside metabolic process GO:0009118 2 0.019
membrane fusion GO:0061025 2 0.019
actin filament polymerization GO:0030041 2 0.019
cell part morphogenesis GO:0032990 246 0.019
leukocyte proliferation GO:0070661 1 0.019
cell cycle g2 m phase transition GO:0044839 4 0.019
chemical homeostasis GO:0048878 49 0.019
regulation of cell death GO:0010941 103 0.019
regulation of establishment of protein localization GO:0070201 4 0.019
positive regulation of cellular component biogenesis GO:0044089 3 0.019
adult behavior GO:0030534 2 0.019
nucleic acid metabolic process GO:0090304 244 0.019
membrane invagination GO:0010324 1 0.018
response to carbohydrate GO:0009743 3 0.018
meiotic cell cycle process GO:1903046 3 0.018
ion transport GO:0006811 114 0.018
regulation of myotube differentiation GO:0010830 2 0.018
positive regulation of cellular amine metabolic process GO:0033240 0 0.018
myotube cell development GO:0014904 35 0.018
rna localization GO:0006403 4 0.018
somite specification GO:0001757 12 0.018
regulation of cell shape GO:0008360 1 0.018
regulation of dna templated transcription elongation GO:0032784 3 0.018
nuclear import GO:0051170 3 0.018
positive regulation of cell activation GO:0050867 1 0.018
gene expression GO:0010467 252 0.018
positive regulation of blood circulation GO:1903524 2 0.018
immune system process GO:0002376 241 0.018
stem cell fate commitment GO:0048865 1 0.018
cell morphogenesis GO:0000902 289 0.018
positive regulation of catabolic process GO:0009896 4 0.018
protein stabilization GO:0050821 2 0.017
regulation of nucleotide catabolic process GO:0030811 2 0.017
regulation of rho protein signal transduction GO:0035023 2 0.017
regulation of wnt signaling pathway GO:0030111 53 0.017
centrosome cycle GO:0007098 1 0.017
microtubule organizing center organization GO:0031023 1 0.017
regulation of receptor activity GO:0010469 2 0.017
defense response to fungus GO:0050832 2 0.017
organelle organization GO:0006996 227 0.017
hemopoiesis GO:0030097 183 0.017
cellular component disassembly GO:0022411 1 0.017
intracellular mrna localization GO:0008298 1 0.017
maternal determination of anterior posterior axis embryo GO:0008358 4 0.017
neurotransmitter secretion GO:0007269 2 0.017
neurotransmitter transport GO:0006836 2 0.017
viral process GO:0016032 1 0.017
positive regulation of secretion GO:0051047 1 0.016
transcription dna templated GO:0006351 181 0.016
ribonucleoside monophosphate catabolic process GO:0009158 4 0.016
taxis GO:0042330 109 0.016
twitch skeletal muscle contraction GO:0014721 4 0.016
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.016
regulation of response to stimulus GO:0048583 269 0.016
regulation of reactive oxygen species metabolic process GO:2000377 2 0.016
gland development GO:0048732 143 0.016
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.016
developmental growth GO:0048589 166 0.016
cellular component assembly GO:0022607 170 0.016
positive regulation of endothelial cell migration GO:0010595 2 0.016
transmembrane transport GO:0055085 120 0.016
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.016
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.016
embryo development ending in birth or egg hatching GO:0009792 271 0.016
response to monosaccharide GO:0034284 3 0.016
regulation of blood vessel size GO:0050880 2 0.016
regulation of sequestering of calcium ion GO:0051282 4 0.016
single organism metabolic process GO:0044710 217 0.016
regulation of cellular component organization GO:0051128 86 0.016
pole plasm assembly GO:0007315 4 0.015
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.015
protein complex disassembly GO:0043241 1 0.015
negative regulation of protein phosphorylation GO:0001933 4 0.015
regulation of protein polymerization GO:0032271 2 0.015
apoptotic process involved in development GO:1902742 2 0.015
gtp metabolic process GO:0046039 4 0.015
regulation of transporter activity GO:0032409 2 0.015
regulation of mrna splicing via spliceosome GO:0048024 3 0.015
bmp signaling pathway GO:0030509 52 0.015
organic acid metabolic process GO:0006082 31 0.015
organelle assembly GO:0070925 110 0.015
dorsal ventral pattern formation GO:0009953 125 0.015
regulation of circadian rhythm GO:0042752 4 0.015
regulation of protein complex disassembly GO:0043244 1 0.015
sleep GO:0030431 1 0.015
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.015
positive regulation of gtp catabolic process GO:0033126 1 0.015
positive regulation of biological process GO:0048518 253 0.015
locomotor rhythm GO:0045475 3 0.014
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.014
cytokinetic process GO:0032506 2 0.014
cell morphogenesis involved in differentiation GO:0000904 195 0.014
localization of cell GO:0051674 244 0.014
muscle fiber development GO:0048747 52 0.014
neuroblast fate commitment GO:0014017 1 0.014
protein polymerization GO:0051258 4 0.014
sequestering of metal ion GO:0051238 3 0.014
head development GO:0060322 303 0.014
negative regulation of protein transport GO:0051224 3 0.014
cell cycle arrest GO:0007050 1 0.014
cardiac atrium development GO:0003230 4 0.014
response to amine GO:0014075 1 0.014
macromolecule localization GO:0033036 54 0.014
negative regulation of cytokine production GO:0001818 1 0.014
regulation of purine nucleotide catabolic process GO:0033121 2 0.013
oocyte anterior posterior axis specification GO:0007314 4 0.013
adherens junction organization GO:0034332 4 0.013
cell matrix adhesion GO:0007160 4 0.013
atp catabolic process GO:0006200 4 0.013
positive regulation of dna metabolic process GO:0051054 1 0.013
protein import GO:0017038 3 0.013
g1 s transition of mitotic cell cycle GO:0000082 1 0.013
stem cell proliferation GO:0072089 4 0.013
cell substrate adhesion GO:0031589 4 0.013
blood vessel development GO:0001568 246 0.013
histone h3 k4 methylation GO:0051568 2 0.013
regulation of mrna processing GO:0050684 3 0.013
regulation of stem cell proliferation GO:0072091 2 0.013
regulation of cytokine production GO:0001817 3 0.013
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.013
protein complex assembly GO:0006461 30 0.013
regulation of ph GO:0006885 3 0.013
central nervous system neuron differentiation GO:0021953 74 0.013
inositol lipid mediated signaling GO:0048017 2 0.013
smooth muscle contraction GO:0006939 2 0.013
positive regulation of multi organism process GO:0043902 3 0.013
inorganic cation transmembrane transport GO:0098662 50 0.013
regulation of systemic arterial blood pressure GO:0003073 1 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.013
epithelial cell differentiation GO:0030855 116 0.013
negative regulation of signal transduction GO:0009968 94 0.013
chordate embryonic development GO:0043009 271 0.013
positive regulation of gtpase activity GO:0043547 1 0.013
lens fiber cell development GO:0070307 3 0.012
tissue remodeling GO:0048771 4 0.012
notochord development GO:0030903 54 0.012
single organism transport GO:0044765 206 0.012
single organism organelle organization GO:1902589 199 0.012
central nervous system development GO:0007417 387 0.012
posterior lateral line system development GO:0048915 46 0.012
negative regulation of wnt signaling pathway GO:0030178 30 0.012
positive regulation of translation GO:0045727 1 0.012
transport GO:0006810 220 0.012
cell aging GO:0007569 2 0.012
protein homooligomerization GO:0051260 3 0.012
intracellular signal transduction GO:0035556 85 0.012
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.012
regulation of phosphorus metabolic process GO:0051174 43 0.012
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.012
lens development in camera type eye GO:0002088 22 0.012
positive regulation of cellular process GO:0048522 201 0.012
protein depolymerization GO:0051261 1 0.012
cellular protein catabolic process GO:0044257 4 0.012
negative regulation of protein kinase activity GO:0006469 4 0.012
regulation of tube size GO:0035150 2 0.012
nuclear transport GO:0051169 4 0.012
autophagy GO:0006914 4 0.012
protein import into nucleus GO:0006606 3 0.012
regulation of transport GO:0051049 45 0.012
regulation of purine nucleotide biosynthetic process GO:1900371 15 0.012
connective tissue development GO:0061448 99 0.012
guanosine containing compound metabolic process GO:1901068 4 0.012
regulation of synapse organization GO:0050807 3 0.012
regulation of organelle assembly GO:1902115 4 0.012
embryonic organ morphogenesis GO:0048562 274 0.012
protein targeting to nucleus GO:0044744 3 0.012
growth GO:0040007 174 0.012
neuron neuron synaptic transmission GO:0007270 1 0.012
enzyme linked receptor protein signaling pathway GO:0007167 106 0.012
post embryonic organ development GO:0048569 4 0.012
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.012
g2 m transition of mitotic cell cycle GO:0000086 4 0.012
dna templated transcription elongation GO:0006354 3 0.012
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.012
digestive tract morphogenesis GO:0048546 231 0.011
neuroblast fate determination GO:0007400 1 0.011
inner ear development GO:0048839 126 0.011
response to wounding GO:0009611 116 0.011
behavior GO:0007610 74 0.011
regulation of multicellular organismal process GO:0051239 277 0.011
cardiac atrium morphogenesis GO:0003209 2 0.011
nucleoside phosphate metabolic process GO:0006753 28 0.011
regulation of cellular ph GO:0030641 1 0.011
regulation of dna replication GO:0006275 3 0.011
cellular amino acid metabolic process GO:0006520 7 0.011
peptidyl lysine acetylation GO:0018394 2 0.011
phosphorus metabolic process GO:0006793 109 0.011
regulation of microtubule cytoskeleton organization GO:0070507 3 0.011
brain development GO:0007420 293 0.011
response to external biotic stimulus GO:0043207 97 0.011
establishment of localization GO:0051234 244 0.011
regulation of epithelial cell proliferation GO:0050678 3 0.011
centrosome organization GO:0051297 1 0.011
glycerolipid biosynthetic process GO:0045017 1 0.011
myofibril assembly GO:0030239 48 0.011
gastrulation GO:0007369 208 0.011
centrosome duplication GO:0051298 1 0.011
cellular response to reactive oxygen species GO:0034614 2 0.011
cellular response to chemical stimulus GO:0070887 157 0.011
response to hexose GO:0009746 3 0.011
antimicrobial humoral response GO:0019730 2 0.011
reactive oxygen species biosynthetic process GO:1903409 1 0.011
cell fate commitment GO:0045165 99 0.011
carboxylic acid metabolic process GO:0019752 22 0.011
regulation of epidermis development GO:0045682 2 0.011
spermatid differentiation GO:0048515 2 0.011
positive regulation of map kinase activity GO:0043406 3 0.011
somatic muscle development GO:0007525 4 0.011
somitogenesis GO:0001756 87 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
phosphate containing compound metabolic process GO:0006796 108 0.011
negative regulation of multicellular organismal process GO:0051241 69 0.011
negative regulation of response to stimulus GO:0048585 104 0.011
regulation of sodium ion transport GO:0002028 2 0.011
regulation of gtpase activity GO:0043087 2 0.011
negative regulation of apoptotic process GO:0043066 55 0.011
regulation of synaptic plasticity GO:0048167 1 0.011
striated muscle cell differentiation GO:0051146 129 0.011
response to hydrogen peroxide GO:0042542 3 0.011
oxoacid metabolic process GO:0043436 31 0.011
negative regulation of signaling GO:0023057 96 0.011
cellular component biogenesis GO:0044085 178 0.011
neuron projection development GO:0031175 180 0.011
positive regulation of epithelial cell migration GO:0010634 2 0.011
angiogenesis GO:0001525 158 0.010
regulation of protein binding GO:0043393 3 0.010
neuron differentiation GO:0030182 353 0.010
positive regulation of dna templated transcription elongation GO:0032786 1 0.010
negative regulation of mapk cascade GO:0043409 4 0.010
negative regulation of cytoplasmic transport GO:1903650 2 0.010
synaptic growth at neuromuscular junction GO:0051124 2 0.010
spermatid development GO:0007286 2 0.010
regulation of lyase activity GO:0051339 12 0.010
sensory organ development GO:0007423 393 0.010
segmentation GO:0035282 97 0.010
programmed cell death GO:0012501 119 0.010
regulation of axonogenesis GO:0050770 32 0.010
skeletal system morphogenesis GO:0048705 102 0.010
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.010
mesoderm development GO:0007498 88 0.010
axon guidance GO:0007411 86 0.010
embryonic limb morphogenesis GO:0030326 2 0.010
internal peptidyl lysine acetylation GO:0018393 2 0.010
positive regulation of cellular biosynthetic process GO:0031328 68 0.010

flnca disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.053
nervous system disease DOID:863 0 0.018
myopathy DOID:423 0 0.014
muscular disease DOID:0080000 0 0.014
musculoskeletal system disease DOID:17 0 0.014
muscle tissue disease DOID:66 0 0.014
disease of metabolism DOID:0014667 0 0.011