Danio rerio

73 known processes

tgif1

TGFB-induced factor homeobox 1

(Aliases: fa06h05,fb33g11,Tgif,zgc:55852,wu:fa06h05,wu:fb33g11)

tgif1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of metabolic process GO:0019222 359 0.912
Human Zebrafish Mouse
regulation of gene expression GO:0010468 265 0.897
Human Zebrafish Mouse
nucleobase containing compound metabolic process GO:0006139 274 0.839
Human Zebrafish Mouse
signal transduction GO:0007165 455 0.701
cellular nitrogen compound biosynthetic process GO:0044271 218 0.671
Human Zebrafish Mouse
nitrogen compound metabolic process GO:0006807 319 0.667
Human Zebrafish Mouse
regulation of macromolecule biosynthetic process GO:0010556 225 0.662
Human Zebrafish Mouse
heterocycle biosynthetic process GO:0018130 215 0.647
Human Zebrafish Mouse
macromolecule biosynthetic process GO:0009059 227 0.636
Human Zebrafish Mouse
cellular macromolecule metabolic process GO:0044260 391 0.577
Human Zebrafish Mouse
locomotion GO:0040011 313 0.577
Zebrafish
heterocycle metabolic process GO:0046483 290 0.566
Human Zebrafish Mouse
gene expression GO:0010467 252 0.562
Human Zebrafish Mouse
regulation of nitrogen compound metabolic process GO:0051171 251 0.534
Human Zebrafish Mouse
aromatic compound biosynthetic process GO:0019438 217 0.523
Human Zebrafish Mouse
regulation of establishment of protein localization GO:0070201 4 0.505
organic substance biosynthetic process GO:1901576 289 0.502
Human Zebrafish Mouse
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.497
Human Zebrafish Mouse
regulation of cell communication GO:0010646 232 0.483
immune system process GO:0002376 241 0.483
Zebrafish
regulation of cellular metabolic process GO:0031323 320 0.476
Human Zebrafish Mouse
generation of neurons GO:0048699 385 0.460
Mouse
rna metabolic process GO:0016070 219 0.445
Human Zebrafish Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.423
Human Zebrafish Mouse
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.414
Human Zebrafish Mouse
cellular nitrogen compound metabolic process GO:0034641 290 0.413
Human Zebrafish Mouse
cellular macromolecule biosynthetic process GO:0034645 224 0.405
Human Zebrafish Mouse
cellular biosynthetic process GO:0044249 286 0.400
Human Zebrafish Mouse
rna biosynthetic process GO:0032774 181 0.395
Human Zebrafish Mouse
cellular component movement GO:0006928 335 0.372
Zebrafish
regulation of nucleic acid templated transcription GO:1903506 213 0.368
Human Zebrafish Mouse
regulation of cellular biosynthetic process GO:0031326 245 0.363
Human Zebrafish Mouse
small molecule metabolic process GO:0044281 77 0.361
response to stress GO:0006950 263 0.361
organic cyclic compound metabolic process GO:1901360 301 0.359
Human Zebrafish Mouse
cell morphogenesis involved in differentiation GO:0000904 195 0.347
cell part morphogenesis GO:0032990 246 0.334
regulation of macromolecule metabolic process GO:0060255 317 0.334
Human Zebrafish Mouse
nucleobase containing compound biosynthetic process GO:0034654 205 0.320
Human Zebrafish Mouse
organic cyclic compound biosynthetic process GO:1901362 223 0.309
Human Zebrafish Mouse
cell morphogenesis GO:0000902 289 0.291
transport GO:0006810 220 0.287
cell projection organization GO:0030030 284 0.282
cellular component morphogenesis GO:0032989 336 0.282
negative regulation of biological process GO:0048519 304 0.281
Human Mouse
transcription dna templated GO:0006351 181 0.281
Human Zebrafish Mouse
positive regulation of map kinase activity GO:0043406 3 0.280
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.280
neuron projection morphogenesis GO:0048812 161 0.275
regulation of anatomical structure morphogenesis GO:0022603 130 0.254
Zebrafish Mouse
negative regulation of cellular process GO:0048523 283 0.248
Human Mouse
intracellular signal transduction GO:0035556 85 0.238
cell migration GO:0016477 237 0.235
Zebrafish
negative regulation of cellular metabolic process GO:0031324 77 0.235
Human Mouse
regulation of primary metabolic process GO:0080090 311 0.232
Human Zebrafish Mouse
nucleic acid metabolic process GO:0090304 244 0.231
Human Zebrafish Mouse
cell death GO:0008219 121 0.220
positive regulation of cellular process GO:0048522 201 0.219
Zebrafish Mouse
response to external stimulus GO:0009605 264 0.208
single organism organelle organization GO:1902589 199 0.201
negative regulation of cellular biosynthetic process GO:0031327 55 0.199
Human Mouse
biosynthetic process GO:0009058 294 0.192
Human Zebrafish Mouse
response to growth factor GO:0070848 39 0.191
cellular response to dna damage stimulus GO:0006974 24 0.189
neuron differentiation GO:0030182 353 0.180
Mouse
response to abiotic stimulus GO:0009628 122 0.180
regulation of signaling GO:0023051 235 0.176
sensory organ development GO:0007423 393 0.170
Zebrafish Mouse
response to organic substance GO:0010033 153 0.169
hematopoietic or lymphoid organ development GO:0048534 191 0.166
Zebrafish
programmed cell death GO:0012501 119 0.164
single organism metabolic process GO:0044710 217 0.164
neuron development GO:0048666 262 0.157
neuron projection development GO:0031175 180 0.155
organelle organization GO:0006996 227 0.153
regionalization GO:0003002 274 0.147
single organism localization GO:1902578 225 0.146
regulation of biosynthetic process GO:0009889 250 0.144
Human Zebrafish Mouse
regulation of mrna splicing via spliceosome GO:0048024 3 0.142
regulation of transcription dna templated GO:0006355 213 0.141
Human Zebrafish Mouse
cellular response to stress GO:0033554 62 0.137
regulation of transcription from rna polymerase iii promoter GO:0006359 1 0.136
regulation of rna metabolic process GO:0051252 224 0.131
Human Zebrafish Mouse
negative regulation of transcription dna templated GO:0045892 45 0.129
Human Mouse
neuron projection guidance GO:0097485 86 0.129
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.127
Zebrafish
nucleocytoplasmic transport GO:0006913 4 0.123
negative regulation of gene expression GO:0010629 65 0.120
Human Mouse
nucleic acid templated transcription GO:0097659 181 0.119
Human Zebrafish Mouse
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.118
Human Mouse
negative regulation of response to stimulus GO:0048585 104 0.116
Mouse
establishment of localization GO:0051234 244 0.114
cell motility GO:0048870 244 0.113
Zebrafish
cellular response to chemical stimulus GO:0070887 157 0.113
negative regulation of mrna processing GO:0050686 1 0.112
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.111
Human Zebrafish Mouse
death GO:0016265 121 0.110
muscle structure development GO:0061061 196 0.110
tube morphogenesis GO:0035239 349 0.110
Zebrafish Mouse
regulation of signal transduction GO:0009966 225 0.109
establishment of localization in cell GO:0051649 77 0.109
embryo development ending in birth or egg hatching GO:0009792 271 0.108
Zebrafish Mouse
cellular ketone metabolic process GO:0042180 11 0.106
cell projection morphogenesis GO:0048858 244 0.104
apoptotic process GO:0006915 116 0.104
anterior posterior pattern specification GO:0009952 152 0.102
single organism transport GO:0044765 206 0.102
regulation of intracellular protein transport GO:0033157 3 0.101
aging GO:0007568 2 0.100
meiotic nuclear division GO:0007126 4 0.098
regulation of response to stimulus GO:0048583 269 0.098
positive regulation of cell cycle GO:0045787 3 0.096
immune system development GO:0002520 191 0.096
Zebrafish
rna polyadenylation GO:0043631 2 0.095
protein import into nucleus GO:0006606 3 0.095
regulation of apoptotic process GO:0042981 98 0.093
retinoic acid receptor signaling pathway GO:0048384 16 0.092
negative regulation of kinase activity GO:0033673 4 0.091
negative regulation of cell death GO:0060548 60 0.090
positive regulation of catabolic process GO:0009896 4 0.090
negative regulation of macromolecule metabolic process GO:0010605 76 0.089
Human Mouse
negative regulation of developmental process GO:0051093 65 0.089
positive regulation of cellular catabolic process GO:0031331 3 0.088
negative regulation of signaling GO:0023057 96 0.086
Mouse
meiosis i GO:0007127 1 0.084
positive regulation of transport GO:0051050 2 0.083
digestive tract development GO:0048565 265 0.083
Mouse
regulation of stem cell proliferation GO:0072091 2 0.082
meiotic cell cycle process GO:1903046 3 0.081
female gonad development GO:0008585 4 0.081
regulation of multicellular organism growth GO:0040014 4 0.080
heart development GO:0007507 313 0.079
Zebrafish
negative regulation of metabolic process GO:0009892 86 0.078
Human Mouse
regulation of biological quality GO:0065008 263 0.078
Zebrafish Worm
axonogenesis GO:0007409 152 0.077
positive regulation of biosynthetic process GO:0009891 68 0.077
Zebrafish
stem cell maintenance GO:0019827 4 0.076
regulation of purine nucleotide catabolic process GO:0033121 2 0.076
protein metabolic process GO:0019538 183 0.076
positive regulation of biological process GO:0048518 253 0.072
Zebrafish Mouse
transcription from rna polymerase iii promoter GO:0006383 1 0.072
regulation of gtp catabolic process GO:0033124 2 0.072
regeneration GO:0031099 91 0.071
response to light stimulus GO:0009416 46 0.070
sensory organ morphogenesis GO:0090596 200 0.069
Zebrafish
regulation of nucleoside metabolic process GO:0009118 2 0.069
tissue regeneration GO:0042246 74 0.068
larval development GO:0002164 2 0.068
regulation of epithelial cell proliferation GO:0050678 3 0.067
epiboly GO:0090504 41 0.066
epithelial cell differentiation GO:0030855 116 0.066
Zebrafish
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.065
Zebrafish
cell surface receptor signaling pathway GO:0007166 325 0.064
positive regulation of gene expression GO:0010628 71 0.064
Zebrafish
negative regulation of cell cycle process GO:0010948 9 0.063
positive regulation of cellular biosynthetic process GO:0031328 68 0.063
Zebrafish
regulation of cell differentiation GO:0045595 142 0.062
Mouse
hemopoiesis GO:0030097 183 0.061
Zebrafish
regulation of multicellular organismal process GO:0051239 277 0.060
Zebrafish Mouse
axon development GO:0061564 166 0.060
negative regulation of cell communication GO:0010648 96 0.060
Mouse
mitotic cell cycle checkpoint GO:0007093 5 0.059
axon guidance GO:0007411 86 0.059
cellular protein metabolic process GO:0044267 129 0.058
regulation of developmental process GO:0050793 247 0.058
Zebrafish Mouse
response to radiation GO:0009314 51 0.057
guanosine containing compound catabolic process GO:1901069 2 0.054
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.054
apoptotic signaling pathway GO:0097190 23 0.054
stem cell development GO:0048864 82 0.054
negative regulation of cell differentiation GO:0045596 46 0.054
segmentation GO:0035282 97 0.052
negative regulation of programmed cell death GO:0043069 58 0.052
organic acid metabolic process GO:0006082 31 0.052
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.052
negative regulation of biosynthetic process GO:0009890 55 0.051
Human Mouse
regulation of rna biosynthetic process GO:2001141 213 0.051
Human Zebrafish Mouse
regulation of circadian rhythm GO:0042752 4 0.051
wound healing GO:0042060 90 0.051
positive regulation of rna metabolic process GO:0051254 59 0.050
Zebrafish
lipid metabolic process GO:0006629 52 0.050
cellular response to lipopolysaccharide GO:0071222 3 0.050
regulation of intracellular signal transduction GO:1902531 57 0.049
stem cell differentiation GO:0048863 117 0.049
regulation of gene expression epigenetic GO:0040029 11 0.048
convergent extension GO:0060026 118 0.048
mitotic dna integrity checkpoint GO:0044774 4 0.047
gtp catabolic process GO:0006184 2 0.046
negative regulation of cell cycle phase transition GO:1901988 5 0.046
response to chemical GO:0042221 320 0.046
growth GO:0040007 174 0.045
positive regulation of transcription dna templated GO:0045893 57 0.045
Zebrafish
guanosine containing compound metabolic process GO:1901068 4 0.044
negative regulation of apoptotic process GO:0043066 55 0.044
alternative mrna splicing via spliceosome GO:0000380 1 0.044
chemotaxis GO:0006935 104 0.043
organonitrogen compound metabolic process GO:1901564 74 0.043
response to wounding GO:0009611 116 0.043
positive regulation of secretion by cell GO:1903532 1 0.043
microtubule based process GO:0007017 60 0.043
eye development GO:0001654 277 0.043
Zebrafish Mouse
negative regulation of protein kinase activity GO:0006469 4 0.042
cell cycle process GO:0022402 53 0.042
Zebrafish
maintenance of gastrointestinal epithelium GO:0030277 7 0.042
development of primary female sexual characteristics GO:0046545 4 0.042
muscle cell differentiation GO:0042692 139 0.042
positive regulation of secretion GO:0051047 1 0.041
mitotic cell cycle process GO:1903047 48 0.041
Zebrafish
regulation of neural precursor cell proliferation GO:2000177 3 0.041
negative regulation of protein phosphorylation GO:0001933 4 0.041
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.041
transcription from rna polymerase ii promoter GO:0006366 80 0.041
Human Zebrafish Mouse
extrinsic apoptotic signaling pathway GO:0097191 3 0.040
regulation of cell development GO:0060284 100 0.040
Mouse
camera type eye morphogenesis GO:0048593 108 0.040
Zebrafish
cognition GO:0050890 1 0.040
protein acylation GO:0043543 3 0.040
regulation of binding GO:0051098 3 0.040
mesenchyme development GO:0060485 127 0.040
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.039
cell cycle GO:0007049 93 0.039
Zebrafish
carboxylic acid metabolic process GO:0019752 22 0.039
nuclear division GO:0000280 23 0.039
cell substrate adhesion GO:0031589 4 0.038
homeostatic process GO:0042592 142 0.038
Zebrafish
cellular response to biotic stimulus GO:0071216 3 0.038
skeletal system morphogenesis GO:0048705 102 0.038
Zebrafish
regulation of response to stress GO:0080134 36 0.038
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.038
carbohydrate derivative metabolic process GO:1901135 61 0.038
oxoacid metabolic process GO:0043436 31 0.038
spliceosomal complex assembly GO:0000245 1 0.037
retina development in camera type eye GO:0060041 146 0.037
Zebrafish Mouse
regulation of cytoplasmic transport GO:1903649 4 0.037
regulation of programmed cell death GO:0043067 101 0.037
response to endogenous stimulus GO:0009719 83 0.037
retina morphogenesis in camera type eye GO:0060042 79 0.036
Zebrafish
meiotic spindle organization GO:0000212 1 0.036
muscle organ development GO:0007517 101 0.036
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.035
Human Mouse
modification dependent macromolecule catabolic process GO:0043632 3 0.035
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.035
Human Mouse
single organism nuclear import GO:1902593 3 0.035
enzyme linked receptor protein signaling pathway GO:0007167 106 0.035
macromolecular complex subunit organization GO:0043933 74 0.035
organic substance transport GO:0071702 58 0.035
negative regulation of mitotic cell cycle phase transition GO:1901991 5 0.034
response to biotic stimulus GO:0009607 97 0.034
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.034
positive regulation of nucleic acid templated transcription GO:1903508 57 0.034
Zebrafish
regulation of cellular protein metabolic process GO:0032268 52 0.034
protein modification process GO:0036211 100 0.034
lipid storage GO:0019915 1 0.034
Worm
regulation of cytokine production GO:0001817 3 0.034
vasculature development GO:0001944 278 0.034
Zebrafish
phosphorus metabolic process GO:0006793 109 0.033
gastrulation GO:0007369 208 0.033
Mouse
nuclear transport GO:0051169 4 0.033
cellular localization GO:0051641 97 0.033
regulation of multicellular organismal development GO:2000026 223 0.033
Zebrafish Mouse
regulation of cell size GO:0008361 29 0.033
peptidyl lysine acetylation GO:0018394 2 0.033
maintenance of location GO:0051235 4 0.033
Worm
mrna splicing via spliceosome GO:0000398 10 0.033
purine containing compound metabolic process GO:0072521 29 0.033
intracellular receptor signaling pathway GO:0030522 30 0.033
response to axon injury GO:0048678 14 0.032
positive regulation of cellular component biogenesis GO:0044089 3 0.032
negative regulation of cellular protein metabolic process GO:0032269 16 0.032
fertilization GO:0009566 3 0.032
ion transport GO:0006811 114 0.032
somite development GO:0061053 96 0.032
cellular response to growth factor stimulus GO:0071363 39 0.032
cellular response to extracellular stimulus GO:0031668 2 0.032
anatomical structure homeostasis GO:0060249 36 0.031
skeletal system development GO:0001501 181 0.031
Zebrafish
somitogenesis GO:0001756 87 0.031
eye morphogenesis GO:0048592 144 0.031
Zebrafish
phosphate containing compound metabolic process GO:0006796 108 0.031
single organism biosynthetic process GO:0044711 71 0.031
myeloid cell differentiation GO:0030099 86 0.031
Zebrafish
gtp metabolic process GO:0046039 4 0.031
regulation of cell cycle GO:0051726 52 0.030
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.030
Zebrafish
formation of primary germ layer GO:0001704 62 0.030
cellular amine metabolic process GO:0044106 2 0.030
regulation of cellular ketone metabolic process GO:0010565 7 0.030
regulation of cellular component size GO:0032535 30 0.030
positive regulation of macromolecule metabolic process GO:0010604 93 0.029
Zebrafish
regulation of translational initiation GO:0006446 1 0.029
regulation of cell motility GO:2000145 46 0.029
cellular response to organic cyclic compound GO:0071407 38 0.029
regulation of localization GO:0032879 104 0.029
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.028
Human Mouse
female sex differentiation GO:0046660 4 0.028
sensory system development GO:0048880 76 0.028
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.028
Human Mouse
post embryonic organ development GO:0048569 4 0.028
regulation of reproductive process GO:2000241 4 0.028
negative regulation of multicellular organismal process GO:0051241 69 0.028
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.028
regulation of gtpase activity GO:0043087 2 0.027
regulation of carbohydrate metabolic process GO:0006109 4 0.027
protein import GO:0017038 3 0.027
mitotic nuclear division GO:0007067 18 0.027
male meiosis GO:0007140 2 0.027
erk1 and erk2 cascade GO:0070371 4 0.027
translational initiation GO:0006413 3 0.027
neuron projection extension GO:1990138 45 0.027
phosphorylation GO:0016310 69 0.026
post embryonic morphogenesis GO:0009886 4 0.026
neuroblast differentiation GO:0014016 1 0.026
protein stabilization GO:0050821 2 0.026
Zebrafish
cell fate commitment GO:0045165 99 0.026
sex determination GO:0007530 1 0.025
response to oxygen containing compound GO:1901700 55 0.025
negative regulation of mrna splicing via spliceosome GO:0048025 1 0.025
negative regulation of signal transduction GO:0009968 94 0.025
Mouse
establishment of endothelial barrier GO:0061028 3 0.025
phagocytosis GO:0006909 3 0.025
dna biosynthetic process GO:0071897 3 0.025
positive regulation of nucleotide catabolic process GO:0030813 1 0.025
regulation of cellular amino acid metabolic process GO:0006521 0 0.025
establishment of protein localization to organelle GO:0072594 4 0.025
mrna polyadenylation GO:0006378 2 0.024
response to retinoic acid GO:0032526 6 0.024
spindle assembly GO:0051225 2 0.024
cytoskeleton organization GO:0007010 96 0.024
cytokinesis GO:0000910 3 0.024
forebrain cell migration GO:0021885 1 0.024
cellular response to lipid GO:0071396 39 0.024
regulation of protein binding GO:0043393 3 0.024
protein acetylation GO:0006473 2 0.024
negative regulation of nucleic acid templated transcription GO:1903507 45 0.024
Human Mouse
biological adhesion GO:0022610 40 0.024
mitotic dna damage checkpoint GO:0044773 4 0.024
regulation of mrna processing GO:0050684 3 0.023
neuron death GO:0070997 21 0.023
regulation of nucleotide catabolic process GO:0030811 2 0.023
positive regulation of reproductive process GO:2000243 2 0.023
positive regulation of rna biosynthetic process GO:1902680 57 0.023
Zebrafish
regulation of erk1 and erk2 cascade GO:0070372 4 0.023
developmental growth GO:0048589 166 0.023
photoreceptor cell differentiation GO:0046530 55 0.023
proteasomal protein catabolic process GO:0010498 2 0.023
regulation of locomotion GO:0040012 55 0.023
negative regulation of synapse assembly GO:0051964 2 0.023
regulation of protein transport GO:0051223 3 0.023
regulation of protein catabolic process GO:0042176 1 0.023
regulation of cellular protein catabolic process GO:1903362 1 0.023
regulation of transport GO:0051049 45 0.023
regulation of synapse assembly GO:0051963 3 0.022
regulation of apoptotic signaling pathway GO:2001233 12 0.022
response to drug GO:0042493 3 0.022
synaptic growth at neuromuscular junction GO:0051124 2 0.022
cellular response to oxygen levels GO:0071453 1 0.022
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.022
intracellular transport GO:0046907 32 0.022
embryonic organ development GO:0048568 381 0.022
Zebrafish
skin development GO:0043588 54 0.022
positive regulation of cellular metabolic process GO:0031325 94 0.022
Zebrafish
regulation of molecular function GO:0065009 70 0.022
positive regulation of gtp catabolic process GO:0033126 1 0.022
single fertilization GO:0007338 3 0.022
positive regulation of developmental process GO:0051094 50 0.022
Zebrafish Mouse
cardiac cell fate commitment GO:0060911 1 0.022
cellular response to radiation GO:0071478 4 0.022
response to hormone GO:0009725 48 0.021
endoderm development GO:0007492 49 0.021
notochord development GO:0030903 54 0.021
regulation of cell death GO:0010941 103 0.021
determination of bilateral symmetry GO:0009855 204 0.021
Zebrafish Mouse
regulation of nervous system development GO:0051960 90 0.021
Mouse
regulation of metal ion transport GO:0010959 4 0.021
cell cycle g1 s phase transition GO:0044843 1 0.021
Zebrafish
regulation of protein complex assembly GO:0043254 3 0.021
stem cell proliferation GO:0072089 4 0.021
regulation of cell cycle phase transition GO:1901987 8 0.021
forebrain regionalization GO:0021871 4 0.021
taxis GO:0042330 109 0.021
organic substance catabolic process GO:1901575 28 0.021
microtubule cytoskeleton organization GO:0000226 33 0.021
response to hydrogen peroxide GO:0042542 3 0.021
positive regulation of stem cell proliferation GO:2000648 1 0.021
cellular response to endogenous stimulus GO:0071495 68 0.021
regulation of cellular amine metabolic process GO:0033238 0 0.020
negative regulation of rna biosynthetic process GO:1902679 45 0.020
Human Mouse
amine metabolic process GO:0009308 2 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.020
osteoclast differentiation GO:0030316 1 0.020
regulation of cellular component organization GO:0051128 86 0.020
response to steroid hormone GO:0048545 35 0.020
negative regulation of cytokine production GO:0001818 1 0.020
sexual reproduction GO:0019953 36 0.020
mesenchymal cell development GO:0014031 78 0.019
multicellular organismal reproductive process GO:0048609 35 0.019
regulation of nucleocytoplasmic transport GO:0046822 2 0.019
internal protein amino acid acetylation GO:0006475 2 0.019
regulation of glial cell differentiation GO:0045685 4 0.019
macromolecule modification GO:0043412 111 0.019
modification dependent protein catabolic process GO:0019941 3 0.019
cellular component biogenesis GO:0044085 178 0.019
macromolecule localization GO:0033036 54 0.019
Worm
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.019
negative regulation of cell cycle GO:0045786 14 0.019
cellular response to external stimulus GO:0071496 2 0.019
dorsal ventral pattern formation GO:0009953 125 0.018
Mouse
nucleotide metabolic process GO:0009117 28 0.018
macromolecular complex disassembly GO:0032984 1 0.018
regulation of anatomical structure size GO:0090066 33 0.018
adherens junction organization GO:0034332 4 0.018
establishment of epithelial cell polarity GO:0090162 2 0.018
circadian rhythm GO:0007623 19 0.018
single organism behavior GO:0044708 24 0.018
cellular protein modification process GO:0006464 100 0.018
positive regulation of cell differentiation GO:0045597 30 0.018
Mouse
embryonic hemopoiesis GO:0035162 53 0.018
Zebrafish
neuroblast proliferation GO:0007405 2 0.018
endothelium development GO:0003158 25 0.018
Zebrafish
cell death in response to oxidative stress GO:0036473 2 0.018
odontogenesis of dentin containing tooth GO:0042475 1 0.018
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.018
cell fate specification GO:0001708 68 0.018
negative regulation of nervous system development GO:0051961 22 0.018
central nervous system neuron differentiation GO:0021953 74 0.018
regulation of protein metabolic process GO:0051246 56 0.018
intracellular estrogen receptor signaling pathway GO:0030520 3 0.018
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 8 0.018
positive regulation of cyclin dependent protein serine threonine kinase activity GO:0045737 1 0.017
ameboidal type cell migration GO:0001667 143 0.017
multi organism reproductive process GO:0044703 36 0.017
fin regeneration GO:0031101 51 0.017
neuron remodeling GO:0016322 1 0.017
regulation of cell migration GO:0030334 40 0.017
mitotic cell cycle embryonic GO:0045448 2 0.017
digestive system development GO:0055123 289 0.017
Zebrafish Mouse
skeletal muscle organ development GO:0060538 78 0.017
positive regulation of neural precursor cell proliferation GO:2000179 1 0.017
regulation of mitotic cell cycle phase transition GO:1901990 8 0.017
single organism reproductive process GO:0044702 40 0.017
positive regulation of jun kinase activity GO:0043507 2 0.017
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 4 0.017
ubiquitin dependent protein catabolic process GO:0006511 3 0.017
myotube differentiation GO:0014902 45 0.017
behavior GO:0007610 74 0.016
positive regulation of apoptotic signaling pathway GO:2001235 1 0.016
cell cycle checkpoint GO:0000075 7 0.016
metal ion homeostasis GO:0055065 26 0.016
positive regulation of dna metabolic process GO:0051054 1 0.016
cellular amino acid metabolic process GO:0006520 7 0.016
negative regulation of nuclear division GO:0051784 3 0.016
signal transduction in absence of ligand GO:0038034 1 0.016
purine nucleotide metabolic process GO:0006163 27 0.016
camera type eye development GO:0043010 222 0.016
Zebrafish Mouse
somatic stem cell maintenance GO:0035019 1 0.016
cell migration involved in gastrulation GO:0042074 79 0.016
negative regulation of gliogenesis GO:0014014 1 0.016
hindbrain development GO:0030902 91 0.016
Zebrafish
negative regulation of apoptotic signaling pathway GO:2001234 10 0.016
muscle tissue development GO:0060537 110 0.016
heart morphogenesis GO:0003007 156 0.015
Zebrafish
system process GO:0003008 185 0.015
cellular response to retinoic acid GO:0071300 1 0.015
protein phosphorylation GO:0006468 47 0.015
catabolic process GO:0009056 32 0.015
multi organism process GO:0051704 134 0.015
connective tissue development GO:0061448 99 0.015
reciprocal dna recombination GO:0035825 1 0.015
cellular component disassembly GO:0022411 1 0.015
establishment of cell polarity GO:0030010 18 0.015
regulation of cell shape GO:0008360 1 0.015
regulation of stem cell differentiation GO:2000736 4 0.015
dna metabolic process GO:0006259 27 0.015
negative regulation of translational initiation GO:0045947 1 0.015
positive regulation of gtpase activity GO:0043547 1 0.015
posterior lateral line system development GO:0048915 46 0.015
axon extension GO:0048675 45 0.015
regulation of dna replication GO:0006275 3 0.015
cell projection assembly GO:0030031 64 0.015
neurological system process GO:0050877 62 0.014
response to lipid GO:0033993 60 0.014
regulation of dna metabolic process GO:0051052 11 0.014
ribose phosphate metabolic process GO:0019693 27 0.014
regulation of organ morphogenesis GO:2000027 35 0.014
positive regulation of metabolic process GO:0009893 108 0.014
Zebrafish

tgif1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.067
nervous system disease DOID:863 0 0.067
sensory system disease DOID:0050155 0 0.043
eye and adnexa disease DOID:1492 0 0.043
eye disease DOID:5614 0 0.043
colon carcinoma DOID:1520 0 0.021
large intestine cancer DOID:5672 0 0.021
colon cancer DOID:219 0 0.021
gastrointestinal system cancer DOID:3119 0 0.021
intestinal cancer DOID:10155 0 0.021
cancer DOID:162 0 0.021
disease of cellular proliferation DOID:14566 0 0.021
organ system cancer DOID:0050686 0 0.021
colorectal cancer DOID:9256 0 0.021