Danio rerio

0 known processes

clrn1

clarin 1

(Aliases: zgc:91933)

clrn1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sensory organ development GO:0007423 393 0.967
sensory organ morphogenesis GO:0090596 200 0.868
mechanoreceptor differentiation GO:0042490 37 0.573
photoreceptor cell differentiation GO:0046530 55 0.507
amino acid transport GO:0006865 2 0.485
camera type eye development GO:0043010 222 0.438
ion transport GO:0006811 114 0.388
camera type eye morphogenesis GO:0048593 108 0.361
generation of neurons GO:0048699 385 0.358
neuron differentiation GO:0030182 353 0.343
inner ear development GO:0048839 126 0.336
hair cell differentiation GO:0035315 32 0.305
neuron neuron synaptic transmission GO:0007270 1 0.304
retina morphogenesis in camera type eye GO:0060042 79 0.303
eye development GO:0001654 277 0.301
eye morphogenesis GO:0048592 144 0.246
cell projection organization GO:0030030 284 0.205
ear morphogenesis GO:0042471 64 0.194
neuroblast proliferation GO:0007405 2 0.193
ear development GO:0043583 127 0.187
photoreceptor cell development GO:0042461 40 0.182
neuromuscular process controlling balance GO:0050885 3 0.176
retina development in camera type eye GO:0060041 146 0.170
eye photoreceptor cell development GO:0042462 30 0.167
system process GO:0003008 185 0.157
photoreceptor cell outer segment organization GO:0035845 9 0.153
detection of stimulus GO:0051606 29 0.151
adult behavior GO:0030534 2 0.135
response to stress GO:0006950 263 0.134
neuron development GO:0048666 262 0.133
regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902175 2 0.123
retina layer formation GO:0010842 24 0.121
sensory system development GO:0048880 76 0.112
dicarboxylic acid transport GO:0006835 1 0.107
embryonic organ development GO:0048568 381 0.107
inner ear receptor cell development GO:0060119 20 0.099
cognition GO:0050890 1 0.096
positive regulation of synapse assembly GO:0051965 1 0.092
multicellular organismal homeostasis GO:0048871 29 0.089
polarized epithelial cell differentiation GO:0030859 4 0.088
locomotion GO:0040011 313 0.087
morphogenesis of an epithelium GO:0002009 333 0.085
regulation of synapse organization GO:0050807 3 0.083
epidermis development GO:0008544 48 0.083
detection of stimulus involved in sensory perception GO:0050906 21 0.083
sensory perception of mechanical stimulus GO:0050954 16 0.079
regulation of response to oxidative stress GO:1902882 2 0.079
embryonic organ morphogenesis GO:0048562 274 0.079
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.078
digestive tract development GO:0048565 265 0.077
establishment of epithelial cell polarity GO:0090162 2 0.074
neurological system process GO:0050877 62 0.072
response to abiotic stimulus GO:0009628 122 0.070
neurotransmitter transport GO:0006836 2 0.070
cellular component assembly GO:0022607 170 0.068
neural retina development GO:0003407 49 0.068
detection of mechanical stimulus involved in sensory perception GO:0050974 11 0.067
positive regulation of secretion by cell GO:1903532 1 0.067
regulation of synapse assembly GO:0051963 3 0.065
inner ear morphogenesis GO:0042472 63 0.064
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.064
positive regulation of transport GO:0051050 2 0.063
cell projection morphogenesis GO:0048858 244 0.063
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 2 0.062
cell death in response to oxidative stress GO:0036473 2 0.061
response to light stimulus GO:0009416 46 0.060
eye photoreceptor cell differentiation GO:0001754 45 0.060
digestive tract morphogenesis GO:0048546 231 0.060
sodium ion transmembrane transport GO:0035725 21 0.057
negative regulation of biological process GO:0048519 304 0.057
organelle organization GO:0006996 227 0.057
regulation of neurotransmitter transport GO:0051588 1 0.057
regulation of localization GO:0032879 104 0.056
regulation of metabolic process GO:0019222 359 0.056
establishment of cell polarity GO:0030010 18 0.056
mechanosensory behavior GO:0007638 2 0.055
detection of abiotic stimulus GO:0009582 24 0.055
blood vessel development GO:0001568 246 0.054
regulation of oxidative stress induced cell death GO:1903201 2 0.053
regulation of biological quality GO:0065008 263 0.053
cell morphogenesis GO:0000902 289 0.053
synaptic growth at neuromuscular junction GO:0051124 2 0.052
regulation of synaptic plasticity GO:0048167 1 0.052
single organism localization GO:1902578 225 0.052
aging GO:0007568 2 0.051
multicellular organism growth GO:0035264 4 0.050
detection of mechanical stimulus GO:0050982 11 0.050
anion transport GO:0006820 38 0.050
response to amino acid GO:0043200 2 0.049
regulation of protein complex assembly GO:0043254 3 0.049
neuronal ion channel clustering GO:0045161 4 0.048
digestive system development GO:0055123 289 0.048
cell death GO:0008219 121 0.048
regulation of neurotransmitter secretion GO:0046928 1 0.048
inner ear receptor stereocilium organization GO:0060122 8 0.048
blood vessel morphogenesis GO:0048514 216 0.046
cellular component movement GO:0006928 335 0.045
cellular component morphogenesis GO:0032989 336 0.044
stem cell division GO:0017145 1 0.043
nucleobase containing compound biosynthetic process GO:0034654 205 0.043
embryonic skeletal system morphogenesis GO:0048704 93 0.043
heart development GO:0007507 313 0.043
epidermal cell differentiation GO:0009913 36 0.041
cell motility GO:0048870 244 0.041
regulation of multicellular organismal process GO:0051239 277 0.040
response to external stimulus GO:0009605 264 0.040
response to radiation GO:0009314 51 0.040
multicellular organismal signaling GO:0035637 22 0.039
negative regulation of protein phosphorylation GO:0001933 4 0.039
negative regulation of cellular process GO:0048523 283 0.038
sensory perception GO:0007600 39 0.037
epithelial cell differentiation GO:0030855 116 0.037
neurotransmitter secretion GO:0007269 2 0.037
response to chemical GO:0042221 320 0.037
developmental growth involved in morphogenesis GO:0060560 86 0.037
positive regulation of biological process GO:0048518 253 0.037
detection of visible light GO:0009584 12 0.037
cell fate commitment GO:0045165 99 0.037
carboxylic acid transport GO:0046942 8 0.036
cellular nitrogen compound metabolic process GO:0034641 290 0.035
innervation GO:0060384 3 0.035
neuron projection extension GO:1990138 45 0.035
cell part morphogenesis GO:0032990 246 0.035
chordate embryonic development GO:0043009 271 0.035
cellular component biogenesis GO:0044085 178 0.035
embryonic cranial skeleton morphogenesis GO:0048701 90 0.034
hindbrain development GO:0030902 91 0.034
epiboly GO:0090504 41 0.034
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.034
endoderm development GO:0007492 49 0.034
neuromast development GO:0048884 46 0.033
retinal cone cell differentiation GO:0042670 12 0.033
regulation of biosynthetic process GO:0009889 250 0.031
positive regulation of secretion GO:0051047 1 0.031
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.030
behavior GO:0007610 74 0.030
cellular amine metabolic process GO:0044106 2 0.030
inner ear receptor cell differentiation GO:0060113 29 0.030
lateral line system development GO:0048925 76 0.029
exocytosis GO:0006887 1 0.029
synaptic transmission GO:0007268 35 0.028
regulation of multicellular organism growth GO:0040014 4 0.028
regeneration GO:0031099 91 0.028
regulation of postsynaptic membrane potential GO:0060078 1 0.027
regionalization GO:0003002 274 0.027
adherens junction organization GO:0034332 4 0.027
visual behavior GO:0007632 10 0.027
spermatid differentiation GO:0048515 2 0.027
developmental growth GO:0048589 166 0.027
vasculature development GO:0001944 278 0.026
glial cell proliferation GO:0014009 4 0.026
regulation of purine nucleotide biosynthetic process GO:1900371 15 0.026
detection of mechanical stimulus involved in sensory perception of sound GO:0050910 3 0.026
head development GO:0060322 303 0.026
odontogenesis of dentin containing tooth GO:0042475 1 0.026
regulation of cellular response to oxidative stress GO:1900407 2 0.025
single organism membrane fusion GO:0044801 2 0.025
cranial nerve development GO:0021545 42 0.025
cellular response to chemical stimulus GO:0070887 157 0.025
inorganic ion transmembrane transport GO:0098660 57 0.025
regulation of metal ion transport GO:0010959 4 0.025
regulation of reproductive process GO:2000241 4 0.025
regulation of multicellular organismal development GO:2000026 223 0.025
regulation of cyclic nucleotide metabolic process GO:0030799 15 0.025
detection of light stimulus GO:0009583 12 0.024
regulation of cell death GO:0010941 103 0.024
establishment of organelle localization GO:0051656 45 0.024
visual perception GO:0007601 17 0.024
cell migration GO:0016477 237 0.024
ion transmembrane transport GO:0034220 91 0.023
neuron projection guidance GO:0097485 86 0.023
skeletal system morphogenesis GO:0048705 102 0.022
proepicardium development GO:0003342 4 0.022
developmental programmed cell death GO:0010623 4 0.022
regulation of cellular ketone metabolic process GO:0010565 7 0.022
regulation of membrane potential GO:0042391 23 0.022
response to carbohydrate GO:0009743 3 0.022
organic substance transport GO:0071702 58 0.022
positive regulation of exocytosis GO:0045921 1 0.022
intracellular signal transduction GO:0035556 85 0.022
negative regulation of axon regeneration GO:0048681 4 0.022
cellular biosynthetic process GO:0044249 286 0.022
regulation of anatomical structure size GO:0090066 33 0.022
regulation of signaling GO:0023051 235 0.022
sodium ion transport GO:0006814 24 0.022
tube morphogenesis GO:0035239 349 0.021
detection of external stimulus GO:0009581 24 0.021
camera type eye photoreceptor cell differentiation GO:0060219 19 0.021
axonogenesis GO:0007409 152 0.021
calcium mediated signaling GO:0019722 2 0.021
cilium morphogenesis GO:0060271 85 0.021
neuromuscular process GO:0050905 7 0.021
embryonic pattern specification GO:0009880 44 0.021
embryonic retina morphogenesis in camera type eye GO:0060059 22 0.021
regulation of intracellular signal transduction GO:1902531 57 0.021
transmission of nerve impulse GO:0019226 19 0.020
cellular response to external stimulus GO:0071496 2 0.020
cation transport GO:0006812 81 0.020
developmental cell growth GO:0048588 52 0.020
retinal cone cell development GO:0046549 8 0.020
embryo development ending in birth or egg hatching GO:0009792 271 0.020
establishment of localization in cell GO:0051649 77 0.020
hemopoiesis GO:0030097 183 0.020
synapse assembly GO:0007416 9 0.020
negative regulation of programmed cell death GO:0043069 58 0.020
establishment of localization GO:0051234 244 0.019
tissue regeneration GO:0042246 74 0.019
regulation of transmembrane transporter activity GO:0022898 2 0.019
metal ion transport GO:0030001 58 0.019
regulation of anatomical structure morphogenesis GO:0022603 130 0.019
blood circulation GO:0008015 87 0.019
protein secretion GO:0009306 1 0.019
immune system development GO:0002520 191 0.019
membrane hyperpolarization GO:0060081 1 0.019
organelle localization GO:0051640 49 0.019
cardiogenic plate morphogenesis GO:0003142 1 0.019
cellular response to light stimulus GO:0071482 4 0.018
cellular response to extracellular stimulus GO:0031668 2 0.018
skeletal system development GO:0001501 181 0.018
regulation of cell communication GO:0010646 232 0.018
macromolecule biosynthetic process GO:0009059 227 0.018
regulation of synaptic transmission GO:0050804 4 0.018
single organism metabolic process GO:0044710 217 0.018
post embryonic organ development GO:0048569 4 0.018
gastrulation GO:0007369 208 0.018
axon extension GO:0048675 45 0.018
negative regulation of reproductive process GO:2000242 3 0.018
auditory receptor cell morphogenesis GO:0002093 4 0.018
central nervous system development GO:0007417 387 0.018
death GO:0016265 121 0.017
regulation of ion transmembrane transporter activity GO:0032412 2 0.017
negative regulation of multicellular organismal process GO:0051241 69 0.017
synapse organization GO:0050808 21 0.017
peptidyl serine modification GO:0018209 2 0.017
growth GO:0040007 174 0.017
regulation of nitrogen compound metabolic process GO:0051171 251 0.017
regulation of cellular amine metabolic process GO:0033238 0 0.017
positive regulation of cellular component biogenesis GO:0044089 3 0.017
renal filtration GO:0097205 10 0.017
negative regulation of protein kinase activity GO:0006469 4 0.017
centrosome localization GO:0051642 1 0.017
rna biosynthetic process GO:0032774 181 0.017
cytoskeleton organization GO:0007010 96 0.017
embryonic hemopoiesis GO:0035162 53 0.017
single organism organelle organization GO:1902589 199 0.017
actin cytoskeleton organization GO:0030036 63 0.016
positive regulation of notch signaling pathway GO:0045747 3 0.016
transport GO:0006810 220 0.016
positive regulation of purine nucleotide biosynthetic process GO:1900373 8 0.016
urogenital system development GO:0001655 97 0.016
response to drug GO:0042493 3 0.016
organelle transport along microtubule GO:0072384 1 0.016
muscle structure development GO:0061061 196 0.016
regulation of establishment of protein localization GO:0070201 4 0.016
regulation of apoptotic process GO:0042981 98 0.016
organelle fusion GO:0048284 3 0.016
organic anion transport GO:0015711 15 0.015
regulation of exocytosis GO:0017157 1 0.015
embryonic heart tube formation GO:0003144 1 0.015
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.015
heterocycle metabolic process GO:0046483 290 0.015
apoptotic process GO:0006915 116 0.015
cellular response to oxygen levels GO:0071453 1 0.015
regulation of response to cytokine stimulus GO:0060759 3 0.015
stem cell proliferation GO:0072089 4 0.015
otic vesicle development GO:0071599 42 0.015
negative regulation of response to stimulus GO:0048585 104 0.015
anatomical structure homeostasis GO:0060249 36 0.015
peripheral nervous system development GO:0007422 55 0.015
cellular component assembly involved in morphogenesis GO:0010927 107 0.015
spermatid development GO:0007286 2 0.015
establishment of monopolar cell polarity GO:0061162 2 0.015
response to organic substance GO:0010033 153 0.014
larval development GO:0002164 2 0.014
positive regulation of protein complex assembly GO:0031334 2 0.014
cyclic nucleotide metabolic process GO:0009187 18 0.014
brain development GO:0007420 293 0.014
positive regulation of developmental process GO:0051094 50 0.014
small molecule metabolic process GO:0044281 77 0.014
neuromast hair cell differentiation GO:0048886 12 0.014
regulation of cellular biosynthetic process GO:0031326 245 0.014
macromolecule modification GO:0043412 111 0.014
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.014
establishment of apical basal cell polarity GO:0035089 2 0.014
regulation of retina development in camera type eye GO:1902866 2 0.014
stem cell differentiation GO:0048863 117 0.014
meiotic nuclear division GO:0007126 4 0.014
regulation of developmental process GO:0050793 247 0.014
regulation of protein binding GO:0043393 3 0.013
cellular aromatic compound metabolic process GO:0006725 295 0.013
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 1 0.013
regulation of gene expression GO:0010468 265 0.013
nerve development GO:0021675 45 0.013
rhythmic process GO:0048511 21 0.013
neuromast hair cell development GO:0035675 6 0.013
cell proliferation GO:0008283 80 0.013
regulation of protein transport GO:0051223 3 0.013
cellular ketone metabolic process GO:0042180 11 0.013
regulation of macromolecule metabolic process GO:0060255 317 0.013
retinal rod cell development GO:0046548 4 0.013
establishment of spindle localization GO:0051293 12 0.013
negative regulation of metabolic process GO:0009892 86 0.013
locomotory behavior GO:0007626 34 0.013
regulation of programmed cell death GO:0043067 101 0.013
single organism transport GO:0044765 206 0.013
pigmentation GO:0043473 85 0.013
endosomal transport GO:0016197 2 0.013
angiogenesis GO:0001525 158 0.012
establishment or maintenance of monopolar cell polarity GO:0061339 2 0.012
neuron projection morphogenesis GO:0048812 161 0.012
determination of bilateral symmetry GO:0009855 204 0.012
amine metabolic process GO:0009308 2 0.012
positive regulation of epithelial cell differentiation GO:0030858 2 0.012
organic substance biosynthetic process GO:1901576 289 0.012
regulation of cyclic nucleotide biosynthetic process GO:0030802 15 0.012
calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules GO:0016339 2 0.012
regulation of blood vessel size GO:0050880 2 0.012
l amino acid transport GO:0015807 1 0.012
cardiac atrium development GO:0003230 4 0.012
negative regulation of interferon gamma mediated signaling pathway GO:0060336 1 0.012
pharyngeal system development GO:0060037 18 0.012
neuron projection development GO:0031175 180 0.012
sensory perception of sound GO:0007605 9 0.012
actin filament based process GO:0030029 64 0.012
cell substrate adhesion GO:0031589 4 0.012
endocardium morphogenesis GO:0003160 4 0.012
cyclic purine nucleotide metabolic process GO:0052652 18 0.012
monovalent inorganic cation transport GO:0015672 42 0.012
regulation of nucleoside metabolic process GO:0009118 2 0.012
positive regulation of cgmp biosynthetic process GO:0030828 6 0.012
programmed cell death GO:0012501 119 0.012
chemotaxis GO:0006935 104 0.012
response to monosaccharide GO:0034284 3 0.012
cellular macromolecule metabolic process GO:0044260 391 0.012
nonmotile primary cilium assembly GO:0035058 2 0.012
negative regulation of biosynthetic process GO:0009890 55 0.012
cilium organization GO:0044782 71 0.012
cell matrix adhesion GO:0007160 4 0.011
autophagy GO:0006914 4 0.011
cell maturation GO:0048469 23 0.011
positive regulation of striated muscle tissue development GO:0045844 1 0.011
macromolecular complex disassembly GO:0032984 1 0.011
stem cell maintenance GO:0019827 4 0.011
positive regulation of cellular biosynthetic process GO:0031328 68 0.011
cation transmembrane transport GO:0098655 65 0.011
positive regulation of cellular metabolic process GO:0031325 94 0.011
biosynthetic process GO:0009058 294 0.011
macroautophagy GO:0016236 1 0.011
nitrogen compound metabolic process GO:0006807 319 0.011
regulation of tube size GO:0035150 2 0.011
otolith development GO:0048840 32 0.011
cellular response to reactive oxygen species GO:0034614 2 0.011
regulation of cell substrate adhesion GO:0010810 1 0.011
developmental maturation GO:0021700 34 0.011
ameboidal type cell migration GO:0001667 143 0.011
determination of intestine left right asymmetry GO:0071908 2 0.011
negative regulation of multi organism process GO:0043901 3 0.011
taste bud development GO:0061193 3 0.011
regulation of protein polymerization GO:0032271 2 0.011
regulation of cellular component organization GO:0051128 86 0.011
cytokinesis GO:0000910 3 0.010
regulation of wnt signaling pathway GO:0030111 53 0.010
establishment of epithelial cell apical basal polarity GO:0045198 2 0.010
myeloid cell differentiation GO:0030099 86 0.010
regulation of transporter activity GO:0032409 2 0.010
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.010
erythrocyte homeostasis GO:0034101 55 0.010
vasculogenesis GO:0001570 41 0.010
myeloid cell development GO:0061515 32 0.010
angioblast cell migration GO:0035476 9 0.010
cellular component disassembly GO:0022411 1 0.010
fin morphogenesis GO:0033334 53 0.010
transmembrane transport GO:0055085 120 0.010
organic acid metabolic process GO:0006082 31 0.010
maintenance of location GO:0051235 4 0.010
cellular carbohydrate metabolic process GO:0044262 4 0.010

clrn1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.234
nervous system disease DOID:863 0 0.101
sensory system disease DOID:0050155 0 0.037
auditory system disease DOID:2742 0 0.019
nonsyndromic deafness DOID:0050563 0 0.019
immune system disease DOID:2914 0 0.016
retinal disease DOID:5679 0 0.013
eye disease DOID:5614 0 0.013
eye and adnexa disease DOID:1492 0 0.013
musculoskeletal system disease DOID:17 0 0.011