Danio rerio

24 known processes

myhz1.1

myosin, heavy polypeptide 1.1, skeletal muscle

(Aliases: si:ch211-158m24.7,MGC195058,myhc3,sb:cb20,myhc4,wu:fb26a08,myhz1,wu:fb37e12,etID37302.5,wu:fb26f12,myo2hc1)

myhz1.1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
voluntary skeletal muscle contraction GO:0003010 4 1.000
Zebrafish
somite development GO:0061053 96 0.996
actin cytoskeleton organization GO:0030036 63 0.990
Yeast Zebrafish Mouse Worm Fly
regulation of sarcomere organization GO:0060297 2 0.989
Mouse
twitch skeletal muscle contraction GO:0014721 4 0.979
Zebrafish
muscle cell development GO:0055001 115 0.973
Zebrafish Mouse Worm Fly
striated muscle cell differentiation GO:0051146 129 0.972
Zebrafish Mouse Worm Fly
skeletal muscle organ development GO:0060538 78 0.970
Zebrafish Mouse
somitogenesis GO:0001756 87 0.962
cytoskeleton organization GO:0007010 96 0.959
Yeast Zebrafish Mouse Worm Fly
somite specification GO:0001757 12 0.953
larval development GO:0002164 2 0.947
Worm
skeletal myofibril assembly GO:0014866 7 0.944
Zebrafish Mouse Worm Fly
actin filament based process GO:0030029 64 0.921
Yeast Zebrafish Mouse Worm Fly
cellular component assembly involved in morphogenesis GO:0010927 107 0.893
Zebrafish Mouse Worm Fly
single organism organelle organization GO:1902589 199 0.881
Yeast Zebrafish Mouse Worm Fly
embryo development ending in birth or egg hatching GO:0009792 271 0.865
muscle structure development GO:0061061 196 0.857
Zebrafish Mouse Worm Fly
somatic muscle development GO:0007525 4 0.853
Fly
anterior posterior pattern specification GO:0009952 152 0.853
atp catabolic process GO:0006200 4 0.850
Fly
muscle organ development GO:0007517 101 0.835
Zebrafish Mouse Fly
sarcomere organization GO:0045214 26 0.828
Mouse Fly
nucleoside monophosphate catabolic process GO:0009125 4 0.827
Fly
skeletal muscle thin filament assembly GO:0030240 4 0.816
Zebrafish
purine nucleoside monophosphate catabolic process GO:0009128 4 0.811
Fly
actomyosin structure organization GO:0031032 53 0.799
Yeast Zebrafish Mouse Worm Fly
neuron development GO:0048666 262 0.797
Worm
actin filament organization GO:0007015 15 0.795
Zebrafish Fly
slow twitch skeletal muscle fiber contraction GO:0031444 3 0.793
Zebrafish
skeletal muscle contraction GO:0003009 5 0.771
Zebrafish
cellular component morphogenesis GO:0032989 336 0.765
Zebrafish Mouse Worm Fly
neuron recognition GO:0008038 18 0.755
Worm
striated muscle cell development GO:0055002 108 0.747
Zebrafish Mouse Worm Fly
myosin filament organization GO:0031033 6 0.731
Zebrafish Mouse Worm Fly
cellular protein complex assembly GO:0043623 19 0.728
Zebrafish Mouse Worm Fly
inositol lipid mediated signaling GO:0048017 2 0.699
Worm
segmentation GO:0035282 97 0.676
multicellular organismal reproductive process GO:0048609 35 0.663
Worm Fly
cytokinesis GO:0000910 3 0.660
Yeast
system process GO:0003008 185 0.650
Zebrafish Worm Fly
multicellular organismal movement GO:0050879 8 0.631
Zebrafish
axon development GO:0061564 166 0.595
Worm
generation of neurons GO:0048699 385 0.585
Worm
cell projection organization GO:0030030 284 0.565
Worm
nitrogen compound metabolic process GO:0006807 319 0.560
Fly
organonitrogen compound metabolic process GO:1901564 74 0.559
Fly
skeletal muscle myosin thick filament assembly GO:0030241 5 0.550
Mouse Worm Fly
purine ribonucleotide metabolic process GO:0009150 27 0.549
Fly
purine ribonucleoside monophosphate metabolic process GO:0009167 5 0.525
Fly
axonal fasciculation GO:0007413 11 0.503
Worm
organelle organization GO:0006996 227 0.492
Yeast Zebrafish Mouse Worm Fly
myofibril assembly GO:0030239 48 0.479
Zebrafish Mouse Worm Fly
ribose phosphate metabolic process GO:0019693 27 0.470
Fly
reactive nitrogen species metabolic process GO:2001057 0 0.463
glycosyl compound metabolic process GO:1901657 11 0.433
Fly
neuron differentiation GO:0030182 353 0.432
Worm
heart process GO:0003015 71 0.427
muscle system process GO:0003012 20 0.422
Zebrafish Worm Fly
cell division GO:0051301 20 0.419
Yeast
cellular nitrogen compound metabolic process GO:0034641 290 0.399
Fly
organelle assembly GO:0070925 110 0.378
Zebrafish Mouse Worm Fly
heterocycle metabolic process GO:0046483 290 0.378
Fly
anatomical structure homeostasis GO:0060249 36 0.362
regulation of actin cytoskeleton organization GO:0032956 8 0.359
Mouse
response to stress GO:0006950 263 0.350
cell recognition GO:0008037 19 0.341
Worm
muscle tissue development GO:0060537 110 0.337
Zebrafish Mouse
cytoskeleton dependent cytokinesis GO:0061640 3 0.329
Yeast
muscle cell differentiation GO:0042692 139 0.328
Zebrafish Mouse Worm Fly
striated muscle contraction GO:0006941 12 0.327
Zebrafish
myosin filament assembly GO:0031034 6 0.327
Zebrafish Mouse Worm Fly
cell morphogenesis GO:0000902 289 0.322
skeletal muscle tissue development GO:0007519 67 0.318
Zebrafish Mouse
regulation of organelle assembly GO:1902115 4 0.299
Mouse
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.299
protein complex assembly GO:0006461 30 0.297
Zebrafish Mouse Worm Fly
cell migration GO:0016477 237 0.295
Fly
ribonucleoside monophosphate catabolic process GO:0009158 4 0.295
Fly
blood circulation GO:0008015 87 0.277
heart development GO:0007507 313 0.253
small molecule metabolic process GO:0044281 77 0.231
Fly
nucleobase containing compound metabolic process GO:0006139 274 0.230
Fly
nitric oxide metabolic process GO:0046209 2 0.224
purine nucleotide metabolic process GO:0006163 27 0.223
Fly
nucleic acid templated transcription GO:0097659 181 0.213
carbohydrate derivative metabolic process GO:1901135 61 0.212
Fly
locomotion GO:0040011 313 0.209
Worm Fly
regulation of muscle contraction GO:0006937 3 0.204
establishment of localization GO:0051234 244 0.193
Worm
regulation of metabolic process GO:0019222 359 0.193
Fly
regulation of biological quality GO:0065008 263 0.193
Fly
transport GO:0006810 220 0.186
Worm
multi organism process GO:0051704 134 0.184
Worm Fly
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.183
Fly
ribonucleotide metabolic process GO:0009259 27 0.182
Fly
protein complex biogenesis GO:0070271 30 0.181
Zebrafish Mouse Worm Fly
muscle cell cellular homeostasis GO:0046716 5 0.180
regulation of primary metabolic process GO:0080090 311 0.180
purine nucleoside monophosphate metabolic process GO:0009126 5 0.176
Fly
musculoskeletal movement GO:0050881 8 0.171
Zebrafish
mitochondrion organization GO:0007005 4 0.163
muscle attachment GO:0016203 9 0.163
cell cycle GO:0007049 93 0.158
Yeast
cellular aromatic compound metabolic process GO:0006725 295 0.157
Fly
reactive oxygen species biosynthetic process GO:1903409 1 0.150
regulation of gene expression GO:0010468 265 0.148
Fly
cellular component biogenesis GO:0044085 178 0.146
Yeast Zebrafish Mouse Worm Fly
segment specification GO:0007379 12 0.144
macromolecular complex subunit organization GO:0043933 74 0.143
Zebrafish Mouse Worm Fly
regulation of organelle organization GO:0033043 29 0.142
Mouse
multicellular organism reproduction GO:0032504 35 0.142
Worm Fly
cellular biosynthetic process GO:0044249 286 0.141
gene expression GO:0010467 252 0.139
Fly
neuron projection development GO:0031175 180 0.139
Worm
cell cycle process GO:0022402 53 0.138
Yeast
nitric oxide biosynthetic process GO:0006809 2 0.137
multi organism reproductive process GO:0044703 36 0.132
Worm Fly
regulation of protein complex assembly GO:0043254 3 0.125
striated muscle tissue development GO:0014706 110 0.122
Zebrafish Mouse
heart contraction GO:0060047 71 0.122
cell motility GO:0048870 244 0.117
Fly
cardiac myofibril assembly GO:0055003 9 0.114
protein stabilization GO:0050821 2 0.112
Fly
regulation of nucleoside metabolic process GO:0009118 2 0.111
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.106
basement membrane assembly GO:0070831 3 0.105
nucleobase containing small molecule metabolic process GO:0055086 32 0.105
Fly
ribonucleoside metabolic process GO:0009119 11 0.099
Fly
cellular nitrogen compound biosynthetic process GO:0044271 218 0.098
ribonucleoside monophosphate metabolic process GO:0009161 5 0.098
Fly
biosynthetic process GO:0009058 294 0.097
signal transduction GO:0007165 455 0.092
Worm
cellular macromolecular complex assembly GO:0034622 24 0.091
Zebrafish Mouse Worm Fly
embryonic pattern specification GO:0009880 44 0.091
digestive system development GO:0055123 289 0.084
cell morphogenesis involved in differentiation GO:0000904 195 0.083
regulation of nucleotide catabolic process GO:0030811 2 0.081
regulation of mrna splicing via spliceosome GO:0048024 3 0.081
nucleoside phosphate metabolic process GO:0006753 28 0.080
Fly
sexual reproduction GO:0019953 36 0.080
Fly
regulation of purine nucleotide catabolic process GO:0033121 2 0.080
protein polymerization GO:0051258 4 0.079
cytokinetic process GO:0032506 2 0.078
Yeast
endocytosis GO:0006897 16 0.077
Worm
regulation of nitrogen compound metabolic process GO:0051171 251 0.074
macromolecular complex assembly GO:0065003 35 0.074
Zebrafish Mouse Worm Fly
intracellular signal transduction GO:0035556 85 0.073
Worm
response to wounding GO:0009611 116 0.073
maintenance of location GO:0051235 4 0.072
protein complex subunit organization GO:0071822 46 0.072
Zebrafish Mouse Worm Fly
positive regulation of rna biosynthetic process GO:1902680 57 0.072
cell part morphogenesis GO:0032990 246 0.071
stem cell fate determination GO:0048867 1 0.070
aging GO:0007568 2 0.068
response to external biotic stimulus GO:0043207 97 0.065
striated muscle myosin thick filament assembly GO:0071688 6 0.062
Zebrafish Mouse Worm Fly
behavior GO:0007610 74 0.062
Worm
gamete generation GO:0007276 33 0.062
Fly
venous blood vessel morphogenesis GO:0048845 3 0.061
regulation of skeletal muscle fiber development GO:0048742 2 0.060
regulation of heart growth GO:0060420 2 0.060
cardiac muscle fiber development GO:0048739 3 0.059
chordate embryonic development GO:0043009 271 0.059
regulation of cell projection assembly GO:0060491 4 0.057
catabolic process GO:0009056 32 0.055
Fly
nucleotide metabolic process GO:0009117 28 0.054
Fly
glial cell fate determination GO:0007403 1 0.054
axonogenesis GO:0007409 152 0.053
muscle fiber development GO:0048747 52 0.053
Zebrafish Mouse
cellular component movement GO:0006928 335 0.052
Fly
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.052
cardiac muscle contraction GO:0060048 6 0.052
purine containing compound metabolic process GO:0072521 29 0.051
Fly
ventricular cardiac muscle tissue development GO:0003229 3 0.051
cardiac muscle tissue development GO:0048738 48 0.051
regulation of sequestering of calcium ion GO:0051282 4 0.050
regulation of cellular component organization GO:0051128 86 0.049
Mouse
purine nucleoside triphosphate metabolic process GO:0009144 9 0.048
Fly
sensory organ development GO:0007423 393 0.048
regulation of cellular metabolic process GO:0031323 320 0.048
heterocycle biosynthetic process GO:0018130 215 0.047
cell projection morphogenesis GO:0048858 244 0.047
cellular homeostasis GO:0019725 26 0.046
hematopoietic or lymphoid organ development GO:0048534 191 0.046
cellular component assembly GO:0022607 170 0.045
Yeast Zebrafish Mouse Worm Fly
body morphogenesis GO:0010171 16 0.044
Worm
regulation of macromolecule biosynthetic process GO:0010556 225 0.043
regionalization GO:0003002 274 0.042
positive regulation of cell cycle GO:0045787 3 0.042
cardiac muscle myosin thick filament assembly GO:0071690 1 0.042
regulation of nucleic acid templated transcription GO:1903506 213 0.041
single organism metabolic process GO:0044710 217 0.041
Fly
pharynx development GO:0060465 5 0.041
heart morphogenesis GO:0003007 156 0.041
organic cyclic compound metabolic process GO:1901360 301 0.039
Fly
regulation of nucleotide metabolic process GO:0006140 17 0.039
cellular macromolecule biosynthetic process GO:0034645 224 0.039
organic substance biosynthetic process GO:1901576 289 0.039
cell matrix adhesion GO:0007160 4 0.039
stem cell differentiation GO:0048863 117 0.039
regulation of hydrolase activity GO:0051336 28 0.037
hematopoietic stem cell differentiation GO:0060218 20 0.037
blood vessel development GO:0001568 246 0.037
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.036
taxis GO:0042330 109 0.036
regulation of cytoskeleton organization GO:0051493 11 0.036
Mouse
cellular response to chemical stimulus GO:0070887 157 0.035
skeletal muscle fiber development GO:0048741 35 0.035
Zebrafish Mouse
regulation of developmental process GO:0050793 247 0.034
Mouse
response to biotic stimulus GO:0009607 97 0.034
actin filament based movement GO:0030048 1 0.034
cellular component disassembly GO:0022411 1 0.033
muscle contraction GO:0006936 18 0.032
Zebrafish Worm Fly
regulation of rna biosynthetic process GO:2001141 213 0.032
rna metabolic process GO:0016070 219 0.031
regulation of actin filament based process GO:0032970 9 0.030
Mouse
regulation of cellular component biogenesis GO:0044087 12 0.030
Mouse
vesicle mediated transport GO:0016192 22 0.029
Worm
ribonucleoside catabolic process GO:0042454 7 0.029
Fly
cardiac muscle cell differentiation GO:0055007 30 0.028
cell substrate adhesion GO:0031589 4 0.028
mitotic cell cycle GO:0000278 64 0.027
atp metabolic process GO:0046034 5 0.027
Fly
cell surface receptor signaling pathway GO:0007166 325 0.027
tissue remodeling GO:0048771 4 0.027
biological adhesion GO:0022610 40 0.027
cognition GO:0050890 1 0.027
pharyngeal muscle development GO:0043282 4 0.026
cellular response to oxygen levels GO:0071453 1 0.026
synaptic growth at neuromuscular junction GO:0051124 2 0.026
nucleic acid metabolic process GO:0090304 244 0.026
rna biosynthetic process GO:0032774 181 0.026
regulation of response to biotic stimulus GO:0002831 2 0.025
homeostatic process GO:0042592 142 0.025
muscle tissue morphogenesis GO:0060415 7 0.025
cell chemotaxis GO:0060326 17 0.024
regulation of mrna processing GO:0050684 3 0.024
nuclear division GO:0000280 23 0.024
negative regulation of cellular process GO:0048523 283 0.023
sequestering of metal ion GO:0051238 3 0.023
positive regulation of biological process GO:0048518 253 0.023
immune system development GO:0002520 191 0.023
macromolecule biosynthetic process GO:0009059 227 0.023
neurotransmitter secretion GO:0007269 2 0.023
ribonucleoside triphosphate metabolic process GO:0009199 9 0.022
Fly
transcription dna templated GO:0006351 181 0.022
lymphoid lineage cell migration into thymus GO:0097535 4 0.022
neuroblast differentiation GO:0014016 1 0.022
extraocular skeletal muscle development GO:0002074 3 0.022
regulation of blood circulation GO:1903522 32 0.021
cellular cation homeostasis GO:0030003 17 0.021
ventricular cardiac myofibril assembly GO:0055005 4 0.021
renal system development GO:0072001 94 0.021
positive regulation of rna metabolic process GO:0051254 59 0.021
regulation of signal transduction GO:0009966 225 0.021
organelle fission GO:0048285 23 0.021
regulation of myotube differentiation GO:0010830 2 0.021
response to activity GO:0014823 14 0.021
Zebrafish Mouse
regulation of catalytic activity GO:0050790 55 0.021
aromatic compound biosynthetic process GO:0019438 217 0.020
regulation of rna metabolic process GO:0051252 224 0.020
hematopoietic progenitor cell differentiation GO:0002244 23 0.020
negative regulation of sequestering of calcium ion GO:0051283 4 0.020
phosphorus metabolic process GO:0006793 109 0.020
Fly
regulation of heart contraction GO:0008016 32 0.020
regulation of synapse organization GO:0050807 3 0.019
directional locomotion GO:0033058 1 0.019
synaptic transmission cholinergic GO:0007271 4 0.019
single organism catabolic process GO:0044712 13 0.019
Fly
synapse assembly GO:0007416 9 0.018
cardiac muscle tissue morphogenesis GO:0055008 7 0.018
neuroblast fate commitment GO:0014017 1 0.018
meiotic nuclear division GO:0007126 4 0.018
regulation of localization GO:0032879 104 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 9 0.018
Fly
transcription from rna polymerase ii promoter GO:0006366 80 0.018
regulation of reproductive process GO:2000241 4 0.018
regulation of cellular biosynthetic process GO:0031326 245 0.017
cellular response to stress GO:0033554 62 0.017
positive regulation of muscle cell differentiation GO:0051149 1 0.017
phosphate containing compound metabolic process GO:0006796 108 0.017
Fly
cell fate commitment GO:0045165 99 0.017
epithelial tube morphogenesis GO:0060562 148 0.017
regulation of biosynthetic process GO:0009889 250 0.017
cell death in response to oxidative stress GO:0036473 2 0.017
regulation of macromolecule metabolic process GO:0060255 317 0.017
Fly
negative regulation of biological process GO:0048519 304 0.017
post embryonic development GO:0009791 7 0.017
Worm
regulation of synapse assembly GO:0051963 3 0.017
cytosolic calcium ion transport GO:0060401 3 0.016
reactive oxygen species metabolic process GO:0072593 6 0.016
post embryonic morphogenesis GO:0009886 4 0.016
regulation of metal ion transport GO:0010959 4 0.016
regulation of response to stimulus GO:0048583 269 0.016
regulation of calcium ion transport GO:0051924 2 0.016
circulatory system process GO:0003013 87 0.016
response to external stimulus GO:0009605 264 0.016
specification of organ identity GO:0010092 2 0.015
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 2 0.015
regulation of striated muscle cell differentiation GO:0051153 6 0.015
Mouse
cell proliferation GO:0008283 80 0.015
cellular response to biotic stimulus GO:0071216 3 0.015
actin filament polymerization GO:0030041 2 0.015
amine metabolic process GO:0009308 2 0.014
skeletal muscle cell differentiation GO:0035914 5 0.014
positive regulation of programmed cell death GO:0043068 29 0.014
organophosphate metabolic process GO:0019637 37 0.014
Fly
calcium ion homeostasis GO:0055074 19 0.014
neuroblast proliferation GO:0007405 2 0.014
cellular catabolic process GO:0044248 27 0.014
Fly
defense response to other organism GO:0098542 33 0.014
positive regulation of cellular component biogenesis GO:0044089 3 0.014
neurotransmitter transport GO:0006836 2 0.014
nucleoside monophosphate metabolic process GO:0009123 6 0.014
Fly
cellular response to molecule of bacterial origin GO:0071219 3 0.013
long chain fatty acid biosynthetic process GO:0042759 1 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.013
oxoacid metabolic process GO:0043436 31 0.013
purine nucleoside metabolic process GO:0042278 10 0.013
Fly
myeloid leukocyte migration GO:0097529 12 0.013
regulation of cell activation GO:0050865 1 0.013
alternative mrna splicing via spliceosome GO:0000380 1 0.013
metal ion homeostasis GO:0055065 26 0.013
eye photoreceptor cell development GO:0042462 30 0.013
lymphoid lineage cell migration GO:0097534 4 0.013
mitotic sister chromatid segregation GO:0000070 6 0.013
reproductive process GO:0022414 40 0.013
Worm Fly
localization of cell GO:0051674 244 0.012
Fly
chemical homeostasis GO:0048878 49 0.012
skeletal system development GO:0001501 181 0.012
muscle organ morphogenesis GO:0048644 8 0.012
regulation of cytoplasmic transport GO:1903649 4 0.012
oocyte anterior posterior axis specification GO:0007314 4 0.012
endocardial cushion formation GO:0003272 2 0.012
carboxylic acid metabolic process GO:0019752 22 0.012
positive regulation of nucleic acid templated transcription GO:1903508 57 0.012
divalent inorganic cation homeostasis GO:0072507 22 0.012
inner ear development GO:0048839 126 0.012
protein metabolic process GO:0019538 183 0.012
chemotaxis GO:0006935 104 0.012
urogenital system development GO:0001655 97 0.012
pectoral fin morphogenesis GO:0035138 29 0.012
positive regulation of locomotion GO:0040017 14 0.011
hemopoiesis GO:0030097 183 0.011
cellular metal ion homeostasis GO:0006875 16 0.011
notochord development GO:0030903 54 0.011
neuronal action potential GO:0019228 18 0.011
astrocyte differentiation GO:0048708 1 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.011
cartilage development GO:0051216 96 0.011
neutrophil migration GO:1990266 10 0.011
regulation of transcription dna templated GO:0006355 213 0.011
growth GO:0040007 174 0.011
rna localization GO:0006403 4 0.011
regulation of system process GO:0044057 40 0.011
organic acid metabolic process GO:0006082 31 0.011
myotome development GO:0061055 1 0.011
immune system process GO:0002376 241 0.011
organic substance catabolic process GO:1901575 28 0.011
Fly
b cell activation GO:0042113 2 0.010
regulation of signaling GO:0023051 235 0.010
nitric oxide mediated signal transduction GO:0007263 2 0.010
positive regulation of transport GO:0051050 2 0.010
regulation of dendrite development GO:0050773 3 0.010
nucleobase containing compound biosynthetic process GO:0034654 205 0.010
outflow tract morphogenesis GO:0003151 1 0.010
establishment of protein localization to organelle GO:0072594 4 0.010
regulation of programmed cell death GO:0043067 101 0.010
basement membrane organization GO:0071711 5 0.010
regulation of dna templated transcription in response to stress GO:0043620 0 0.010
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.010
regulation of skeletal muscle tissue development GO:0048641 4 0.010

myhz1.1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.093
musculoskeletal system disease DOID:17 0 0.034
kidney disease DOID:557 0 0.026
urinary system disease DOID:18 0 0.026
muscular disease DOID:0080000 0 0.011