Danio rerio

0 known processes

atf1

activating transcription factor 1

(Aliases: wu:fc92c07,zgc:64099)

atf1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic cyclic compound metabolic process GO:1901360 301 0.234
Human
rna metabolic process GO:0016070 219 0.191
Human
cellular aromatic compound metabolic process GO:0006725 295 0.188
Human
nucleic acid metabolic process GO:0090304 244 0.176
Human
larval development GO:0002164 2 0.167
regulation of metabolic process GO:0019222 359 0.149
Human
regulation of multicellular organismal process GO:0051239 277 0.141
negative regulation of biological process GO:0048519 304 0.137
regulation of biological quality GO:0065008 263 0.131
regulation of gene expression GO:0010468 265 0.130
Human
meiotic nuclear division GO:0007126 4 0.126
nitrogen compound metabolic process GO:0006807 319 0.114
Human
cellular macromolecule metabolic process GO:0044260 391 0.105
Human
cellular biosynthetic process GO:0044249 286 0.104
Human
response to stress GO:0006950 263 0.101
regulation of cellular metabolic process GO:0031323 320 0.097
Human
protein dephosphorylation GO:0006470 3 0.096
nuclear transport GO:0051169 4 0.085
gene expression GO:0010467 252 0.083
Human
aging GO:0007568 2 0.082
protein localization to nucleus GO:0034504 3 0.080
nucleocytoplasmic transport GO:0006913 4 0.078
negative regulation of cellular process GO:0048523 283 0.070
regulation of cell communication GO:0010646 232 0.070
positive regulation of transport GO:0051050 2 0.067
organelle organization GO:0006996 227 0.065
embryo development ending in birth or egg hatching GO:0009792 271 0.065
Zebrafish
regulation of signal transduction GO:0009966 225 0.063
heterocycle biosynthetic process GO:0018130 215 0.063
Human
negative regulation of cell communication GO:0010648 96 0.062
aromatic compound biosynthetic process GO:0019438 217 0.061
Human
cellular macromolecule biosynthetic process GO:0034645 224 0.060
Human
cell surface receptor signaling pathway GO:0007166 325 0.058
regulation of meiotic cell cycle GO:0051445 1 0.057
rna biosynthetic process GO:0032774 181 0.057
Human
regulation of macromolecule biosynthetic process GO:0010556 225 0.057
Human
positive regulation of cellular component biogenesis GO:0044089 3 0.057
homeostatic process GO:0042592 142 0.055
protein metabolic process GO:0019538 183 0.055
protein targeting to nucleus GO:0044744 3 0.055
positive regulation of biological process GO:0048518 253 0.053
Human
cellular nitrogen compound metabolic process GO:0034641 290 0.052
Human
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.051
regulation of mrna processing GO:0050684 3 0.050
cellular protein metabolic process GO:0044267 129 0.050
single organism localization GO:1902578 225 0.050
signal transduction GO:0007165 455 0.049
regulation of multicellular organism growth GO:0040014 4 0.049
heterocycle metabolic process GO:0046483 290 0.049
Human
positive regulation of cellular process GO:0048522 201 0.049
Human
protein import into nucleus GO:0006606 3 0.048
regulation of rna metabolic process GO:0051252 224 0.047
Human
response to chemical GO:0042221 320 0.046
organic substance biosynthetic process GO:1901576 289 0.045
Human
nuclear import GO:0051170 3 0.043
positive regulation of cell cycle GO:0045787 3 0.043
hematopoietic or lymphoid organ development GO:0048534 191 0.042
biosynthetic process GO:0009058 294 0.042
Human
regulation of developmental process GO:0050793 247 0.042
mrna metabolic process GO:0016071 20 0.042
digestive system development GO:0055123 289 0.042
meiosis i GO:0007127 1 0.041
single organism nuclear import GO:1902593 3 0.041
regulation of response to stimulus GO:0048583 269 0.040
regulation of macromolecule metabolic process GO:0060255 317 0.040
Human
regulation of signaling GO:0023051 235 0.040
multicellular organism growth GO:0035264 4 0.039
regulation of transcription dna templated GO:0006355 213 0.038
Human
single organism metabolic process GO:0044710 217 0.038
protein stabilization GO:0050821 2 0.038
regulation of localization GO:0032879 104 0.038
meiotic cell cycle process GO:1903046 3 0.038
response to external biotic stimulus GO:0043207 97 0.038
regulation of cellular biosynthetic process GO:0031326 245 0.038
Human
nucleic acid templated transcription GO:0097659 181 0.037
Human
nucleobase containing compound metabolic process GO:0006139 274 0.037
Human
g1 s transition of mitotic cell cycle GO:0000082 1 0.037
regulation of primary metabolic process GO:0080090 311 0.036
Human
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.036
regulation of biosynthetic process GO:0009889 250 0.036
Human
regulation of cell death GO:0010941 103 0.036
sensory organ development GO:0007423 393 0.035
macromolecule biosynthetic process GO:0009059 227 0.035
Human
protein import GO:0017038 3 0.034
ubiquitin dependent protein catabolic process GO:0006511 3 0.034
response to biotic stimulus GO:0009607 97 0.034
programmed cell death GO:0012501 119 0.033
regulation of cytoplasmic transport GO:1903649 4 0.033
regulation of apoptotic process GO:0042981 98 0.033
tube morphogenesis GO:0035239 349 0.032
response to other organism GO:0051707 97 0.032
organic cyclic compound biosynthetic process GO:1901362 223 0.031
Human
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.031
Human
stem cell division GO:0017145 1 0.031
modification dependent macromolecule catabolic process GO:0043632 3 0.031
mrna processing GO:0006397 14 0.031
transcription dna templated GO:0006351 181 0.031
Human
erythrocyte homeostasis GO:0034101 55 0.031
multi organism process GO:0051704 134 0.030
rna processing GO:0006396 25 0.030
multicellular organismal reproductive process GO:0048609 35 0.030
cellular nitrogen compound biosynthetic process GO:0044271 218 0.030
Human
immune system process GO:0002376 241 0.030
establishment of protein localization to organelle GO:0072594 4 0.029
regulation of mrna splicing via spliceosome GO:0048024 3 0.029
cellular component disassembly GO:0022411 1 0.029
positive regulation of protein complex assembly GO:0031334 2 0.029
rna 3 end processing GO:0031123 2 0.029
negative regulation of response to stimulus GO:0048585 104 0.028
cellular protein modification process GO:0006464 100 0.028
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.028
regulation of cell differentiation GO:0045595 142 0.028
regulation of synapse organization GO:0050807 3 0.027
protein acylation GO:0043543 3 0.027
positive regulation of map kinase activity GO:0043406 3 0.026
growth GO:0040007 174 0.026
Zebrafish
regionalization GO:0003002 274 0.026
Zebrafish
cell fate specification GO:0001708 68 0.026
cortical cytoskeleton organization GO:0030865 1 0.026
nucleobase containing compound biosynthetic process GO:0034654 205 0.025
Human
cellular response to stress GO:0033554 62 0.025
reproductive process GO:0022414 40 0.025
regulation of synapse assembly GO:0051963 3 0.024
regulation of multicellular organismal development GO:2000026 223 0.024
cell cycle g1 s phase transition GO:0044843 1 0.024
phosphate containing compound metabolic process GO:0006796 108 0.024
alternative mrna splicing via spliceosome GO:0000380 1 0.024
peptidyl lysine acetylation GO:0018394 2 0.024
regulation of nitrogen compound metabolic process GO:0051171 251 0.024
Human
organic acid metabolic process GO:0006082 31 0.024
central nervous system development GO:0007417 387 0.023
Zebrafish
negative regulation of protein phosphorylation GO:0001933 4 0.023
negative regulation of macromolecule metabolic process GO:0010605 76 0.023
negative regulation of signal transduction GO:0009968 94 0.023
digestive tract development GO:0048565 265 0.023
microtubule based process GO:0007017 60 0.023
negative regulation of metabolic process GO:0009892 86 0.023
macromolecule modification GO:0043412 111 0.023
negative regulation of signaling GO:0023057 96 0.023
gastrulation GO:0007369 208 0.023
apoptotic process GO:0006915 116 0.023
lateral inhibition GO:0046331 1 0.022
myeloid cell homeostasis GO:0002262 56 0.022
establishment of localization in cell GO:0051649 77 0.022
positive regulation of cellular catabolic process GO:0031331 3 0.022
regulation of establishment of protein localization GO:0070201 4 0.022
blood vessel development GO:0001568 246 0.022
regulation of protein transport GO:0051223 3 0.022
compound eye development GO:0048749 2 0.022
cytoskeleton organization GO:0007010 96 0.022
negative regulation of gene expression GO:0010629 65 0.021
embryonic organ development GO:0048568 381 0.021
protein modification process GO:0036211 100 0.021
developmental growth GO:0048589 166 0.021
Zebrafish
single organism organelle organization GO:1902589 199 0.021
positive regulation of cellular biosynthetic process GO:0031328 68 0.021
Human
positive regulation of mrna metabolic process GO:1903313 2 0.021
synaptic growth at neuromuscular junction GO:0051124 2 0.021
autophagy GO:0006914 4 0.021
establishment of localization GO:0051234 244 0.020
organic substance transport GO:0071702 58 0.020
single organism transport GO:0044765 206 0.020
wnt signaling pathway GO:0016055 80 0.020
maintenance of location GO:0051235 4 0.020
peptidyl serine phosphorylation GO:0018105 1 0.020
cell fate commitment GO:0045165 99 0.020
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.019
Human
lipid storage GO:0019915 1 0.019
transport GO:0006810 220 0.019
regulation of autophagy GO:0010506 3 0.019
response to external stimulus GO:0009605 264 0.019
rna localization GO:0006403 4 0.019
regulation of reproductive process GO:2000241 4 0.019
cell morphogenesis GO:0000902 289 0.018
system process GO:0003008 185 0.018
positive regulation of catabolic process GO:0009896 4 0.018
regulation of cell activation GO:0050865 1 0.018
extrinsic apoptotic signaling pathway GO:0097191 3 0.018
regulation of cellular component organization GO:0051128 86 0.018
regulation of nucleocytoplasmic transport GO:0046822 2 0.018
cellular protein catabolic process GO:0044257 4 0.018
mitotic cell cycle process GO:1903047 48 0.018
regulation of stem cell differentiation GO:2000736 4 0.018
anterior posterior pattern specification GO:0009952 152 0.018
Zebrafish
g2 dna damage checkpoint GO:0031572 3 0.018
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.018
response to monosaccharide GO:0034284 3 0.018
nuclear export GO:0051168 1 0.018
regulation of epithelial cell proliferation GO:0050678 3 0.018
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.018
Human
death GO:0016265 121 0.018
homeostasis of number of cells GO:0048872 62 0.018
positive regulation of response to stimulus GO:0048584 80 0.018
protein complex localization GO:0031503 1 0.018
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.018
oxoacid metabolic process GO:0043436 31 0.018
meiotic chromosome segregation GO:0045132 3 0.017
immune system development GO:0002520 191 0.017
intracellular signal transduction GO:0035556 85 0.017
hormone transport GO:0009914 2 0.017
small molecule metabolic process GO:0044281 77 0.017
cellular amino acid metabolic process GO:0006520 7 0.017
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.017
regulation of programmed cell death GO:0043067 101 0.017
actin filament polymerization GO:0030041 2 0.017
carbohydrate homeostasis GO:0033500 1 0.017
mrna 3 end processing GO:0031124 2 0.017
chordate embryonic development GO:0043009 271 0.017
Zebrafish
neuroblast proliferation GO:0007405 2 0.016
lymphocyte proliferation GO:0046651 1 0.016
regulation of hormone secretion GO:0046883 2 0.016
positive regulation of metabolic process GO:0009893 108 0.016
Human
regulation of nucleic acid templated transcription GO:1903506 213 0.016
Human
regulation of stem cell proliferation GO:0072091 2 0.016
negative regulation of catabolic process GO:0009895 3 0.016
chemosensory behavior GO:0007635 1 0.016
modification dependent protein catabolic process GO:0019941 3 0.016
digestive tract morphogenesis GO:0048546 231 0.016
morphogenesis of an epithelium GO:0002009 333 0.016
Zebrafish
negative regulation of synapse assembly GO:0051964 2 0.015
mitotic cell cycle GO:0000278 64 0.015
response to hexose GO:0009746 3 0.015
proteasomal protein catabolic process GO:0010498 2 0.015
embryonic skeletal system development GO:0048706 97 0.015
regulation of cytokine production GO:0001817 3 0.015
response to bacterium GO:0009617 58 0.015
vasculature development GO:0001944 278 0.015
negative regulation of cellular metabolic process GO:0031324 77 0.015
skeletal system development GO:0001501 181 0.015
cellular localization GO:0051641 97 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.015
Human
hormone secretion GO:0046879 2 0.015
stem cell proliferation GO:0072089 4 0.015
regulation of erk1 and erk2 cascade GO:0070372 4 0.015
response to wounding GO:0009611 116 0.015
response to carbohydrate GO:0009743 3 0.015
heart development GO:0007507 313 0.015
regulation of rna biosynthetic process GO:2001141 213 0.015
Human
localization within membrane GO:0051668 1 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.014
regulation of cell shape GO:0008360 1 0.014
regulation of growth rate GO:0040009 1 0.014
negative regulation of kinase activity GO:0033673 4 0.014
positive regulation of rna metabolic process GO:0051254 59 0.014
Human
localization of cell GO:0051674 244 0.014
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.014
blood vessel morphogenesis GO:0048514 216 0.014
cellular component assembly GO:0022607 170 0.014
lipid homeostasis GO:0055088 3 0.014
erk1 and erk2 cascade GO:0070371 4 0.014
positive regulation of secretion GO:0051047 1 0.014
regulation of intracellular protein transport GO:0033157 3 0.014
negative regulation of developmental process GO:0051093 65 0.014
positive regulation of muscle cell differentiation GO:0051149 1 0.014
regulation of cellular amine metabolic process GO:0033238 0 0.014
cellular response to extracellular stimulus GO:0031668 2 0.014
response to glucose GO:0009749 3 0.013
carboxylic acid metabolic process GO:0019752 22 0.013
macromolecular complex subunit organization GO:0043933 74 0.013
cellular carbohydrate metabolic process GO:0044262 4 0.013
entrainment of circadian clock GO:0009649 2 0.013
cellular component morphogenesis GO:0032989 336 0.013
centrosome organization GO:0051297 1 0.013
sex determination GO:0007530 1 0.013
kidney development GO:0001822 92 0.013
hemopoiesis GO:0030097 183 0.013
erythrocyte differentiation GO:0030218 54 0.013
generation of neurons GO:0048699 385 0.013
negative regulation of dna metabolic process GO:0051053 4 0.013
cortical actin cytoskeleton organization GO:0030866 1 0.013
embryonic organ morphogenesis GO:0048562 274 0.013
gamete generation GO:0007276 33 0.013
cell cycle process GO:0022402 53 0.013
regulation of protein ubiquitination GO:0031396 3 0.013
glucose homeostasis GO:0042593 1 0.013
mitotic dna integrity checkpoint GO:0044774 4 0.013
cytokinesis GO:0000910 3 0.013
rna export from nucleus GO:0006405 1 0.013
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.013
guanosine containing compound metabolic process GO:1901068 4 0.013
positive regulation of secretion by cell GO:1903532 1 0.013
cellular response to chemical stimulus GO:0070887 157 0.013
cell cycle GO:0007049 93 0.013
actin polymerization or depolymerization GO:0008154 2 0.013
eye development GO:0001654 277 0.013
cell part morphogenesis GO:0032990 246 0.013
cellular ketone metabolic process GO:0042180 11 0.013
mitotic dna damage checkpoint GO:0044773 4 0.013
peptide transport GO:0015833 1 0.013
adult behavior GO:0030534 2 0.012
regulation of neural precursor cell proliferation GO:2000177 3 0.012
regulation of inflammatory response GO:0050727 2 0.012
microtubule organizing center organization GO:0031023 1 0.012
response to ketone GO:1901654 1 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
leukocyte proliferation GO:0070661 1 0.012
negative regulation of protein kinase activity GO:0006469 4 0.012
cytoskeleton dependent cytokinesis GO:0061640 3 0.012
embryonic limb morphogenesis GO:0030326 2 0.012
cellular amine metabolic process GO:0044106 2 0.012
positive regulation of macromolecule metabolic process GO:0010604 93 0.012
Human
phagocytosis GO:0006909 3 0.012
gtp catabolic process GO:0006184 2 0.012
negative regulation of multicellular organismal process GO:0051241 69 0.012
mitochondrion organization GO:0007005 4 0.012
regulation of protein catabolic process GO:0042176 1 0.012
regulation of binding GO:0051098 3 0.012
regulation of dna templated transcription elongation GO:0032784 3 0.012
regulation of protein localization to nucleus GO:1900180 2 0.012
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.012
protein homooligomerization GO:0051260 3 0.012
primitive hemopoiesis GO:0060215 27 0.011
cell migration GO:0016477 237 0.011
response to organic cyclic compound GO:0014070 51 0.011
organonitrogen compound metabolic process GO:1901564 74 0.011
male meiosis GO:0007140 2 0.011
negative regulation of cell death GO:0060548 60 0.011
regulation of molecular function GO:0065009 70 0.011
regulation of nervous system development GO:0051960 90 0.011
activation of mapk activity GO:0000187 3 0.011
positive regulation of nucleotide catabolic process GO:0030813 1 0.011
leukocyte homeostasis GO:0001776 2 0.011
negative regulation of apoptotic process GO:0043066 55 0.011
membrane fusion GO:0061025 2 0.011
myeloid cell differentiation GO:0030099 86 0.011
transcription from rna polymerase iii promoter GO:0006383 1 0.011
response to uv GO:0009411 3 0.011
mitotic cell cycle embryonic GO:0045448 2 0.011
cell motility GO:0048870 244 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
negative regulation of multi organism process GO:0043901 3 0.011
golgi vesicle transport GO:0048193 3 0.011
positive regulation of nucleic acid templated transcription GO:1903508 57 0.011
Human
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.011
gene silencing GO:0016458 4 0.011
negative regulation of rna splicing GO:0033119 1 0.011
dna templated transcription initiation GO:0006352 1 0.011
carbohydrate biosynthetic process GO:0016051 1 0.011
response to lipid GO:0033993 60 0.011
cellular response to external stimulus GO:0071496 2 0.011
golgi organization GO:0007030 1 0.011
single organism reproductive process GO:0044702 40 0.011
mononuclear cell proliferation GO:0032943 1 0.011
establishment of rna localization GO:0051236 3 0.011
transcription from rna polymerase ii promoter GO:0006366 80 0.011
Human
somatic stem cell maintenance GO:0035019 1 0.011
positive regulation of nucleoside metabolic process GO:0045979 1 0.011
convergent extension GO:0060026 118 0.011
Zebrafish
negative regulation of epithelial cell proliferation GO:0050680 1 0.010
fertilization GO:0009566 3 0.010
mrna catabolic process GO:0006402 6 0.010
behavior GO:0007610 74 0.010
negative regulation of mrna processing GO:0050686 1 0.010
cell morphogenesis involved in differentiation GO:0000904 195 0.010
embryonic skeletal system morphogenesis GO:0048704 93 0.010
regulation of anatomical structure morphogenesis GO:0022603 130 0.010
regulation of purine nucleotide catabolic process GO:0033121 2 0.010
chemical homeostasis GO:0048878 49 0.010
positive regulation of stress activated mapk cascade GO:0032874 3 0.010
cognition GO:0050890 1 0.010
negative regulation of programmed cell death GO:0043069 58 0.010
regulation of protein complex assembly GO:0043254 3 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.010
negative regulation of defense response GO:0031348 2 0.010
internal peptidyl lysine acetylation GO:0018393 2 0.010
camera type eye development GO:0043010 222 0.010
regulation of chromosome segregation GO:0051983 1 0.010
tube closure GO:0060606 1 0.010

atf1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
musculoskeletal system disease DOID:17 0 0.025
nervous system disease DOID:863 0 0.019
muscular disease DOID:0080000 0 0.015
myopathy DOID:423 0 0.015
muscle tissue disease DOID:66 0 0.015
disease of metabolism DOID:0014667 0 0.012
sensory system disease DOID:0050155 0 0.011