Danio rerio

0 known processes

ints2

integrator complex subunit 2

(Aliases: zgc:109975,MGC109975)

ints2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.064
regulation of circadian rhythm GO:0042752 4 0.052
response to drug GO:0042493 3 0.050
aging GO:0007568 2 0.049
extrinsic apoptotic signaling pathway GO:0097191 3 0.046
meiotic cell cycle process GO:1903046 3 0.046
cellular macromolecule metabolic process GO:0044260 391 0.045
nuclear transport GO:0051169 4 0.043
stem cell maintenance GO:0019827 4 0.042
cellular protein metabolic process GO:0044267 129 0.041
hemopoiesis GO:0030097 183 0.038
regulation of biological quality GO:0065008 263 0.033
cellular amine metabolic process GO:0044106 2 0.033
response to chemical GO:0042221 320 0.032
single organism metabolic process GO:0044710 217 0.032
cellular nitrogen compound metabolic process GO:0034641 290 0.030
embryonic organ development GO:0048568 381 0.030
small molecule metabolic process GO:0044281 77 0.029
central nervous system development GO:0007417 387 0.028
mitochondrion organization GO:0007005 4 0.027
regulation of apoptotic process GO:0042981 98 0.027
positive regulation of apoptotic signaling pathway GO:2001235 1 0.027
maintenance of location GO:0051235 4 0.027
mitotic cell cycle process GO:1903047 48 0.026
regulation of developmental process GO:0050793 247 0.026
regulation of cellular metabolic process GO:0031323 320 0.026
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.026
regulation of cellular amine metabolic process GO:0033238 0 0.026
protein import into nucleus GO:0006606 3 0.025
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.025
embryo development ending in birth or egg hatching GO:0009792 271 0.025
nitrogen compound metabolic process GO:0006807 319 0.025
cellular localization GO:0051641 97 0.025
response to hexose GO:0009746 3 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.025
response to glucose GO:0009749 3 0.024
lipid storage GO:0019915 1 0.024
organonitrogen compound metabolic process GO:1901564 74 0.024
cellular amino acid metabolic process GO:0006520 7 0.024
cell surface receptor signaling pathway GO:0007166 325 0.024
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.024
chordate embryonic development GO:0043009 271 0.024
protein stabilization GO:0050821 2 0.024
amine metabolic process GO:0009308 2 0.023
protein modification process GO:0036211 100 0.023
heart development GO:0007507 313 0.023
regulation of cellular amino acid metabolic process GO:0006521 0 0.023
stem cell development GO:0048864 82 0.023
single organism organelle organization GO:1902589 199 0.022
positive regulation of cell cycle GO:0045787 3 0.022
g2 dna damage checkpoint GO:0031572 3 0.022
regulation of establishment of protein localization GO:0070201 4 0.022
regulation of cell differentiation GO:0045595 142 0.022
guanosine containing compound catabolic process GO:1901069 2 0.022
nuclear export GO:0051168 1 0.022
protein acylation GO:0043543 3 0.022
cellular protein modification process GO:0006464 100 0.022
nucleocytoplasmic transport GO:0006913 4 0.021
negative regulation of kinase activity GO:0033673 4 0.021
locomotor rhythm GO:0045475 3 0.020
stem cell proliferation GO:0072089 4 0.019
nucleoside monophosphate catabolic process GO:0009125 4 0.019
response to monosaccharide GO:0034284 3 0.019
organic cyclic compound metabolic process GO:1901360 301 0.019
protein complex localization GO:0031503 1 0.019
hematopoietic or lymphoid organ development GO:0048534 191 0.018
neuron differentiation GO:0030182 353 0.018
protein acetylation GO:0006473 2 0.018
embryonic organ morphogenesis GO:0048562 274 0.018
internal peptidyl lysine acetylation GO:0018393 2 0.018
macromolecule modification GO:0043412 111 0.018
phosphorus metabolic process GO:0006793 109 0.018
organic acid metabolic process GO:0006082 31 0.018
regulation of multicellular organismal development GO:2000026 223 0.018
cellular ketone metabolic process GO:0042180 11 0.017
response to stress GO:0006950 263 0.017
regulation of cell death GO:0010941 103 0.017
internal protein amino acid acetylation GO:0006475 2 0.017
skeletal system development GO:0001501 181 0.017
adherens junction organization GO:0034332 4 0.017
heart morphogenesis GO:0003007 156 0.017
regulation of autophagy GO:0010506 3 0.017
regulation of metabolic process GO:0019222 359 0.017
protein dephosphorylation GO:0006470 3 0.017
heterocycle metabolic process GO:0046483 290 0.017
nucleobase containing compound metabolic process GO:0006139 274 0.017
rna modification GO:0009451 2 0.017
establishment of protein localization to organelle GO:0072594 4 0.016
gtp metabolic process GO:0046039 4 0.016
negative regulation of protein phosphorylation GO:0001933 4 0.016
gtp catabolic process GO:0006184 2 0.016
negative regulation of mapk cascade GO:0043409 4 0.016
homeostasis of number of cells GO:0048872 62 0.016
regulation of protein transport GO:0051223 3 0.016
immune system development GO:0002520 191 0.016
biosynthetic process GO:0009058 294 0.016
negative regulation of developmental process GO:0051093 65 0.016
blood vessel development GO:0001568 246 0.016
g2 m transition of mitotic cell cycle GO:0000086 4 0.016
cell cycle g2 m phase transition GO:0044839 4 0.016
phosphate containing compound metabolic process GO:0006796 108 0.016
lateral line system development GO:0048925 76 0.016
negative regulation of macromolecule metabolic process GO:0010605 76 0.016
neurotransmitter transport GO:0006836 2 0.015
response to biotic stimulus GO:0009607 97 0.015
sensory organ development GO:0007423 393 0.015
regulation of response to nutrient levels GO:0032107 1 0.015
regulation of cytoplasmic transport GO:1903649 4 0.015
response to wounding GO:0009611 116 0.015
cellular response to chemical stimulus GO:0070887 157 0.015
stem cell differentiation GO:0048863 117 0.015
negative regulation of cellular process GO:0048523 283 0.015
cell substrate adhesion GO:0031589 4 0.015
cellular aromatic compound metabolic process GO:0006725 295 0.015
regulation of protein ubiquitination GO:0031396 3 0.015
positive regulation of cellular amine metabolic process GO:0033240 0 0.015
embryonic skeletal system development GO:0048706 97 0.015
positive regulation of transport GO:0051050 2 0.015
protein localization to nucleus GO:0034504 3 0.015
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.015
regulation of nucleoside metabolic process GO:0009118 2 0.015
protein metabolic process GO:0019538 183 0.015
positive regulation of biological process GO:0048518 253 0.015
intracellular signal transduction GO:0035556 85 0.015
maternal determination of anterior posterior axis embryo GO:0008358 4 0.015
regulation of cellular ketone metabolic process GO:0010565 7 0.014
cellular response to oxygen levels GO:0071453 1 0.014
positive regulation of cellular process GO:0048522 201 0.014
response to external stimulus GO:0009605 264 0.014
cellular response to extracellular stimulus GO:0031668 2 0.014
rna localization GO:0006403 4 0.014
cellular component biogenesis GO:0044085 178 0.014
myeloid cell homeostasis GO:0002262 56 0.014
meiotic nuclear division GO:0007126 4 0.014
head development GO:0060322 303 0.014
negative regulation of biological process GO:0048519 304 0.014
regulation of signal transduction GO:0009966 225 0.014
single organism localization GO:1902578 225 0.014
regulation of phosphorus metabolic process GO:0051174 43 0.014
response to organic substance GO:0010033 153 0.014
cellular carbohydrate metabolic process GO:0044262 4 0.013
cell substrate junction assembly GO:0007044 2 0.013
interspecies interaction between organisms GO:0044419 4 0.013
regulation of response to cytokine stimulus GO:0060759 3 0.013
alcohol biosynthetic process GO:0046165 2 0.013
regulation of translational initiation GO:0006446 1 0.013
histone h4 k20 methylation GO:0034770 2 0.013
nuclear import GO:0051170 3 0.013
viral process GO:0016032 1 0.013
cell matrix adhesion GO:0007160 4 0.013
regulation of purine nucleotide catabolic process GO:0033121 2 0.013
mechanosensory lateral line system development GO:0048881 49 0.013
regulation of primary metabolic process GO:0080090 311 0.013
apoptotic process GO:0006915 116 0.013
negative regulation of dna replication GO:0008156 2 0.013
peptidyl lysine acetylation GO:0018394 2 0.013
negative regulation of signal transduction GO:0009968 94 0.013
regulation of catalytic activity GO:0050790 55 0.013
regulation of cell shape GO:0008360 1 0.013
regulation of dna replication GO:0006275 3 0.013
signal transduction GO:0007165 455 0.013
multicellular organism growth GO:0035264 4 0.013
posttranscriptional regulation of gene expression GO:0010608 14 0.013
cellular response to hypoxia GO:0071456 1 0.013
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.013
primitive hemopoiesis GO:0060215 27 0.013
neurological system process GO:0050877 62 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.013
positive regulation of nucleotide catabolic process GO:0030813 1 0.012
g1 s transition of mitotic cell cycle GO:0000082 1 0.012
negative regulation of cytoplasmic transport GO:1903650 2 0.012
gene expression GO:0010467 252 0.012
cell cycle g1 s phase transition GO:0044843 1 0.012
adult behavior GO:0030534 2 0.012
regulation of stem cell proliferation GO:0072091 2 0.012
protein import GO:0017038 3 0.012
tube closure GO:0060606 1 0.012
regulation of response to stimulus GO:0048583 269 0.012
angiogenesis GO:0001525 158 0.012
regulation of cell communication GO:0010646 232 0.012
regulation of cytokine mediated signaling pathway GO:0001959 3 0.012
carboxylic acid metabolic process GO:0019752 22 0.012
oxoacid metabolic process GO:0043436 31 0.012
cognition GO:0050890 1 0.012
protein targeting to nucleus GO:0044744 3 0.012
response to nutrient GO:0007584 3 0.012
cell projection organization GO:0030030 284 0.012
positive regulation of catabolic process GO:0009896 4 0.012
gene silencing by mirna GO:0035195 3 0.012
peptidyl serine modification GO:0018209 2 0.012
atp catabolic process GO:0006200 4 0.012
centrosome duplication GO:0051298 1 0.012
microtubule organizing center organization GO:0031023 1 0.012
cell substrate adherens junction assembly GO:0007045 1 0.012
negative regulation of metabolic process GO:0009892 86 0.012
cellular response to stress GO:0033554 62 0.012
cellular response to nutrient levels GO:0031669 2 0.012
system process GO:0003008 185 0.012
death GO:0016265 121 0.011
regulation of mitochondrion organization GO:0010821 1 0.011
mesenchymal cell development GO:0014031 78 0.011
digestive system development GO:0055123 289 0.011
regulation of cell activation GO:0050865 1 0.011
regulation of protein complex assembly GO:0043254 3 0.011
neuromuscular process controlling balance GO:0050885 3 0.011
somatic muscle development GO:0007525 4 0.011
cellular response to decreased oxygen levels GO:0036294 1 0.011
negative regulation of response to stimulus GO:0048585 104 0.011
positive regulation of nucleoside metabolic process GO:0045979 1 0.011
negative regulation of protein transport GO:0051224 3 0.011
neuroblast proliferation GO:0007405 2 0.011
regulation of signaling GO:0023051 235 0.011
response to external biotic stimulus GO:0043207 97 0.011
multi organism cellular process GO:0044764 2 0.011
tissue remodeling GO:0048771 4 0.011
negative regulation of immune response GO:0050777 2 0.011
circadian rhythm GO:0007623 19 0.011
regulation of biosynthetic process GO:0009889 250 0.011
embryonic hemopoiesis GO:0035162 53 0.011
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.011
negative regulation of multi organism process GO:0043901 3 0.011
establishment of localization GO:0051234 244 0.011
nucleobase containing compound transport GO:0015931 2 0.011
regulation of nitrogen compound metabolic process GO:0051171 251 0.011
homeostatic process GO:0042592 142 0.011
regulation of metal ion transport GO:0010959 4 0.010
negative regulation of axon regeneration GO:0048681 4 0.010
immune system process GO:0002376 241 0.010
regulation of stem cell differentiation GO:2000736 4 0.010
negative regulation of catabolic process GO:0009895 3 0.010
primary neural tube formation GO:0014020 1 0.010
guanosine containing compound metabolic process GO:1901068 4 0.010
negative regulation of cytokine mediated signaling pathway GO:0001960 2 0.010
cellular response to external stimulus GO:0071496 2 0.010
regulation of calcium ion transport GO:0051924 2 0.010
heterocycle biosynthetic process GO:0018130 215 0.010
posterior lateral line development GO:0048916 38 0.010
regulation of reproductive process GO:2000241 4 0.010

ints2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.011