Danio rerio

0 known processes

edem1

ER degradation enhancer, mannosidase alpha-like 1

(Aliases: zgc:55816,MGC55816)

edem1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.188
cellular macromolecule metabolic process GO:0044260 391 0.114
Mouse
signal transduction GO:0007165 455 0.088
cellular nitrogen compound metabolic process GO:0034641 290 0.078
positive regulation of transport GO:0051050 2 0.069
regulation of nitrogen compound metabolic process GO:0051171 251 0.067
cellular amide metabolic process GO:0043603 4 0.067
cell projection morphogenesis GO:0048858 244 0.065
cation transmembrane transport GO:0098655 65 0.063
cellular protein catabolic process GO:0044257 4 0.062
Mouse
central nervous system development GO:0007417 387 0.055
proteasomal protein catabolic process GO:0010498 2 0.053
Mouse
organic substance biosynthetic process GO:1901576 289 0.052
regulation of cell communication GO:0010646 232 0.051
aging GO:0007568 2 0.051
leukocyte mediated cytotoxicity GO:0001909 1 0.049
single organism localization GO:1902578 225 0.046
positive regulation of biological process GO:0048518 253 0.045
axonogenesis GO:0007409 152 0.044
regulation of signaling GO:0023051 235 0.044
transport GO:0006810 220 0.042
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.041
Mouse
skeletal system development GO:0001501 181 0.041
neuron differentiation GO:0030182 353 0.040
establishment of localization GO:0051234 244 0.040
meiotic nuclear division GO:0007126 4 0.040
regulation of tube size GO:0035150 2 0.040
embryonic skeletal system morphogenesis GO:0048704 93 0.039
cell part morphogenesis GO:0032990 246 0.039
cell morphogenesis GO:0000902 289 0.038
cytokinesis GO:0000910 3 0.038
regulation of multicellular organismal process GO:0051239 277 0.037
lipid storage GO:0019915 1 0.037
exocytosis GO:0006887 1 0.037
maintenance of location GO:0051235 4 0.036
cellular component morphogenesis GO:0032989 336 0.036
multi organism process GO:0051704 134 0.035
multicellular organism growth GO:0035264 4 0.035
striated muscle cell differentiation GO:0051146 129 0.035
peptide metabolic process GO:0006518 1 0.035
developmental growth GO:0048589 166 0.035
positive regulation of apoptotic signaling pathway GO:2001235 1 0.034
nitrogen compound metabolic process GO:0006807 319 0.034
inorganic ion transmembrane transport GO:0098660 57 0.034
heterocycle metabolic process GO:0046483 290 0.033
regulation of blood vessel size GO:0050880 2 0.033
intracellular mrna localization GO:0008298 1 0.032
generation of neurons GO:0048699 385 0.032
organonitrogen compound metabolic process GO:1901564 74 0.032
establishment of protein localization to organelle GO:0072594 4 0.032
positive regulation of secretion GO:0051047 1 0.031
cell morphogenesis involved in differentiation GO:0000904 195 0.031
cellular aromatic compound metabolic process GO:0006725 295 0.030
embryonic organ development GO:0048568 381 0.030
organelle organization GO:0006996 227 0.030
head development GO:0060322 303 0.029
cellular biosynthetic process GO:0044249 286 0.028
negative regulation of protein phosphorylation GO:0001933 4 0.028
nucleobase containing compound metabolic process GO:0006139 274 0.027
cell surface receptor signaling pathway GO:0007166 325 0.027
protein modification process GO:0036211 100 0.026
synaptic vesicle localization GO:0097479 1 0.026
muscle cell differentiation GO:0042692 139 0.026
cellular nitrogen compound biosynthetic process GO:0044271 218 0.026
negative regulation of biological process GO:0048519 304 0.026
positive regulation of cellular process GO:0048522 201 0.026
cytoskeleton dependent cytokinesis GO:0061640 3 0.025
cellular amine metabolic process GO:0044106 2 0.025
maternal determination of anterior posterior axis embryo GO:0008358 4 0.025
organelle localization GO:0051640 49 0.025
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.024
Mouse
biosynthetic process GO:0009058 294 0.024
regulation of biological quality GO:0065008 263 0.024
morphogenesis of an epithelium GO:0002009 333 0.024
viral process GO:0016032 1 0.023
regulation of metabolic process GO:0019222 359 0.023
brain development GO:0007420 293 0.023
protein metabolic process GO:0019538 183 0.023
Mouse
muscle structure development GO:0061061 196 0.023
response to chemical GO:0042221 320 0.023
negative regulation of cellular process GO:0048523 283 0.022
regulation of macromolecule metabolic process GO:0060255 317 0.022
cellular component assembly involved in morphogenesis GO:0010927 107 0.022
gtp metabolic process GO:0046039 4 0.022
regulation of multicellular organism growth GO:0040014 4 0.022
death GO:0016265 121 0.021
macromolecule biosynthetic process GO:0009059 227 0.021
positive regulation of secretion by cell GO:1903532 1 0.021
segmentation GO:0035282 97 0.021
synaptic growth at neuromuscular junction GO:0051124 2 0.021
protein targeting to membrane GO:0006612 1 0.021
neurotransmitter secretion GO:0007269 2 0.021
regulation of systemic arterial blood pressure GO:0003073 1 0.020
rna metabolic process GO:0016070 219 0.020
cell projection organization GO:0030030 284 0.020
regulation of cell death GO:0010941 103 0.020
blood circulation GO:0008015 87 0.020
regulation of blood pressure GO:0008217 1 0.020
pole plasm assembly GO:0007315 4 0.020
protein import into nucleus GO:0006606 3 0.019
system process GO:0003008 185 0.019
epithelial cell morphogenesis GO:0003382 2 0.019
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.019
b cell activation GO:0042113 2 0.019
cellular ketone metabolic process GO:0042180 11 0.019
meiotic cell cycle process GO:1903046 3 0.019
ion transmembrane transport GO:0034220 91 0.019
regulation of synapse organization GO:0050807 3 0.019
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.019
regulation of cellular metabolic process GO:0031323 320 0.019
neuron development GO:0048666 262 0.019
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.018
cellular protein metabolic process GO:0044267 129 0.018
Mouse
anterior posterior pattern specification GO:0009952 152 0.018
establishment of localization in cell GO:0051649 77 0.018
tube morphogenesis GO:0035239 349 0.018
modification dependent macromolecule catabolic process GO:0043632 3 0.018
Mouse
negative regulation of signaling GO:0023057 96 0.018
negative regulation of protein kinase activity GO:0006469 4 0.018
regulation of cell shape GO:0008360 1 0.018
localization within membrane GO:0051668 1 0.018
regulation of dna templated transcription in response to stress GO:0043620 0 0.018
macromolecule modification GO:0043412 111 0.018
establishment of organelle localization GO:0051656 45 0.018
cellular response to topologically incorrect protein GO:0035967 2 0.018
chordate embryonic development GO:0043009 271 0.017
nucleobase containing compound biosynthetic process GO:0034654 205 0.017
positive regulation of macromolecule metabolic process GO:0010604 93 0.017
neuron projection development GO:0031175 180 0.017
circulatory system process GO:0003013 87 0.017
guanosine containing compound metabolic process GO:1901068 4 0.017
positive regulation of cellular catabolic process GO:0031331 3 0.017
regulation of protein catabolic process GO:0042176 1 0.017
heterocycle biosynthetic process GO:0018130 215 0.017
nucleocytoplasmic transport GO:0006913 4 0.017
regulation of biosynthetic process GO:0009889 250 0.017
positive regulation of cell cycle GO:0045787 3 0.017
primary neural tube formation GO:0014020 1 0.017
response to nutrient GO:0007584 3 0.016
single organism transport GO:0044765 206 0.016
regulation of rna metabolic process GO:0051252 224 0.016
regulation of reproductive process GO:2000241 4 0.016
transmembrane transport GO:0055085 120 0.016
nuclear transport GO:0051169 4 0.016
positive regulation of signal transduction GO:0009967 56 0.016
neurotransmitter transport GO:0006836 2 0.016
guanosine containing compound catabolic process GO:1901069 2 0.016
regulation of cellular ketone metabolic process GO:0010565 7 0.015
response to stress GO:0006950 263 0.015
localization of cell GO:0051674 244 0.015
cellular amino acid metabolic process GO:0006520 7 0.015
regulation of nucleotide catabolic process GO:0030811 2 0.015
regulation of metal ion transport GO:0010959 4 0.015
immune system process GO:0002376 241 0.015
organic cyclic compound metabolic process GO:1901360 301 0.015
hormone transport GO:0009914 2 0.015
regulation of signal transduction GO:0009966 225 0.015
positive regulation of catabolic process GO:0009896 4 0.015
regulation of primary metabolic process GO:0080090 311 0.015
regulation of ion transmembrane transporter activity GO:0032412 2 0.015
tube closure GO:0060606 1 0.015
regulation of response to stimulus GO:0048583 269 0.015
amine metabolic process GO:0009308 2 0.015
nucleic acid metabolic process GO:0090304 244 0.015
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.015
response to organic substance GO:0010033 153 0.015
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.014
gene expression GO:0010467 252 0.014
negative regulation of autophagy GO:0010507 1 0.014
chromosome organization involved in meiosis GO:0070192 1 0.014
calcium ion dependent exocytosis GO:0017156 1 0.014
positive regulation of cellular component biogenesis GO:0044089 3 0.014
embryonic cranial skeleton morphogenesis GO:0048701 90 0.014
enzyme linked receptor protein signaling pathway GO:0007167 106 0.014
negative regulation of kinase activity GO:0033673 4 0.014
regionalization GO:0003002 274 0.014
regulation of neurotransmitter secretion GO:0046928 1 0.014
organism emergence from protective structure GO:0071684 4 0.014
cortical actin cytoskeleton organization GO:0030866 1 0.014
regulation of cell activation GO:0050865 1 0.014
response to external stimulus GO:0009605 264 0.014
oocyte anterior posterior axis specification GO:0007314 4 0.014
cellular component assembly GO:0022607 170 0.014
hatching GO:0035188 4 0.014
embryonic organ morphogenesis GO:0048562 274 0.014
muscle cell development GO:0055001 115 0.014
locomotion GO:0040011 313 0.013
cell killing GO:0001906 2 0.013
regulation of gtpase activity GO:0043087 2 0.013
establishment of vesicle localization GO:0051650 24 0.013
embryonic skeletal system development GO:0048706 97 0.013
meiotic chromosome segregation GO:0045132 3 0.013
regulation of apoptotic process GO:0042981 98 0.013
transcription from rna polymerase ii promoter GO:0006366 80 0.013
somatic muscle development GO:0007525 4 0.013
embryo development ending in birth or egg hatching GO:0009792 271 0.013
positive regulation of signaling GO:0023056 56 0.013
regulation of cytokine production GO:0001817 3 0.013
oxoacid metabolic process GO:0043436 31 0.013
cellular protein modification process GO:0006464 100 0.013
intracellular signal transduction GO:0035556 85 0.013
stem cell division GO:0017145 1 0.013
cellular response to nutrient levels GO:0031669 2 0.013
striated muscle cell development GO:0055002 108 0.012
protein targeting to nucleus GO:0044744 3 0.012
myosin filament organization GO:0031033 6 0.012
macroautophagy GO:0016236 1 0.012
protein localization to plasma membrane GO:0072659 1 0.012
synaptic transmission cholinergic GO:0007271 4 0.012
modification dependent protein catabolic process GO:0019941 3 0.012
Mouse
regulation of protein metabolic process GO:0051246 56 0.012
hormone secretion GO:0046879 2 0.012
negative regulation of catabolic process GO:0009895 3 0.012
single organism metabolic process GO:0044710 217 0.012
negative regulation of cellular catabolic process GO:0031330 3 0.012
organic cyclic compound biosynthetic process GO:1901362 223 0.012
regulation of organ growth GO:0046620 3 0.012
skeletal system morphogenesis GO:0048705 102 0.012
single organism organelle organization GO:1902589 199 0.012
cell death GO:0008219 121 0.012
organic substance catabolic process GO:1901575 28 0.012
Mouse
neuron projection morphogenesis GO:0048812 161 0.011
regulation of neurotransmitter transport GO:0051588 1 0.011
regulation of cellular amine metabolic process GO:0033238 0 0.011
ubiquitin dependent protein catabolic process GO:0006511 3 0.011
Mouse
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.011
i kappab kinase nf kappab signaling GO:0007249 4 0.011
female gonad development GO:0008585 4 0.011
mitochondrion organization GO:0007005 4 0.011
response to other organism GO:0051707 97 0.011
embryonic heart tube morphogenesis GO:0003143 108 0.011
regulation of protein complex assembly GO:0043254 3 0.011
positive regulation of translation GO:0045727 1 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.011
phosphorylation GO:0016310 69 0.011
regulation of receptor mediated endocytosis GO:0048259 4 0.011
hemopoiesis GO:0030097 183 0.011
regulation of macromolecule biosynthetic process GO:0010556 225 0.011
positive regulation of cellular metabolic process GO:0031325 94 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
cellular component biogenesis GO:0044085 178 0.011
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.011
positive regulation of blood circulation GO:1903524 2 0.011
rna localization GO:0006403 4 0.011
synaptic vesicle transport GO:0048489 1 0.011
regulation of nucleoside metabolic process GO:0009118 2 0.011
interaction with host GO:0051701 4 0.011
aromatic compound biosynthetic process GO:0019438 217 0.011
cation transport GO:0006812 81 0.011
vacuolar transport GO:0007034 2 0.011
stem cell maintenance GO:0019827 4 0.011
regulation of muscle contraction GO:0006937 3 0.011
cell substrate junction assembly GO:0007044 2 0.011
axon development GO:0061564 166 0.010
mitotic cytokinesis GO:0000281 3 0.010
organic acid metabolic process GO:0006082 31 0.010
autophagy GO:0006914 4 0.010
cellular localization GO:0051641 97 0.010
regulation of sodium ion transport GO:0002028 2 0.010
response to vitamin GO:0033273 3 0.010
peptide transport GO:0015833 1 0.010
regulation of response to extracellular stimulus GO:0032104 1 0.010
regulation of gene expression GO:0010468 265 0.010
cellular response to starvation GO:0009267 1 0.010
development of primary female sexual characteristics GO:0046545 4 0.010
iron ion transmembrane transport GO:0034755 3 0.010
regulation of cell maturation GO:1903429 1 0.010
regulation of protein transport GO:0051223 3 0.010
lysosomal transport GO:0007041 2 0.010
single organism nuclear import GO:1902593 3 0.010
vesicle localization GO:0051648 27 0.010
regulation of hormone secretion GO:0046883 2 0.010
interspecies interaction between organisms GO:0044419 4 0.010
negative regulation of response to cytokine stimulus GO:0060761 2 0.010
digestive system development GO:0055123 289 0.010
regulation of establishment of protein localization GO:0070201 4 0.010
cellular macromolecular complex assembly GO:0034622 24 0.010

edem1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.043
disease of metabolism DOID:0014667 0 0.020
inherited metabolic disorder DOID:655 0 0.020
musculoskeletal system disease DOID:17 0 0.016
immune system disease DOID:2914 0 0.013
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013