Danio rerio

159 known processes

notch1a

notch homolog 1a

(Aliases: des,wu:fc01e02,n1a,wu:fc37a05)

notch1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nucleic acid metabolic process GO:0090304 244 1.000
Human Mouse Rat Fly
positive regulation of biological process GO:0048518 253 1.000
cellular macromolecule biosynthetic process GO:0034645 224 0.999
Human Mouse Rat Fly
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.999
Human Mouse Rat Fly
regulation of nitrogen compound metabolic process GO:0051171 251 0.998
Human Mouse Rat Fly
rna metabolic process GO:0016070 219 0.998
Human Mouse Rat Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.998
Human Mouse Rat Fly
embryo development ending in birth or egg hatching GO:0009792 271 0.998
cell fate commitment GO:0045165 99 0.998
neuron projection development GO:0031175 180 0.997
positive regulation of metabolic process GO:0009893 108 0.997
Human Mouse Rat Fly
regulation of macromolecule biosynthetic process GO:0010556 225 0.997
Human Mouse Rat Fly
regulation of gene expression GO:0010468 265 0.996
Human Mouse Rat Fly
positive regulation of cellular metabolic process GO:0031325 94 0.996
Human Mouse Rat Fly
positive regulation of cellular process GO:0048522 201 0.996
regulation of biosynthetic process GO:0009889 250 0.996
Human Mouse Rat Fly
chordate embryonic development GO:0043009 271 0.996
organic cyclic compound metabolic process GO:1901360 301 0.995
Human Mouse Rat Fly
regulation of primary metabolic process GO:0080090 311 0.994
Human Mouse Rat Fly
positive regulation of notch signaling pathway GO:0045747 3 0.994
Fly
morphogenesis of an epithelium GO:0002009 333 0.994
Mouse Fly
macromolecule biosynthetic process GO:0009059 227 0.993
Human Mouse Rat Fly
generation of neurons GO:0048699 385 0.992
positive regulation of stem cell proliferation GO:2000648 1 0.991
Rat
signal transduction GO:0007165 455 0.991
cellular aromatic compound metabolic process GO:0006725 295 0.990
Human Mouse Rat Fly
positive regulation of rna metabolic process GO:0051254 59 0.990
Human Mouse Rat Fly
nucleic acid templated transcription GO:0097659 181 0.989
Human Mouse Rat Fly
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.989
Human Mouse Rat Fly
ventral spinal cord development GO:0021517 35 0.989
cellular macromolecule metabolic process GO:0044260 391 0.989
Human Mouse Rat Fly
embryonic organ development GO:0048568 381 0.988
regulation of transcription dna templated GO:0006355 213 0.988
Human Mouse Rat Fly
cell differentiation in spinal cord GO:0021515 40 0.988
positive regulation of neural precursor cell proliferation GO:2000179 1 0.988
Rat
biosynthetic process GO:0009058 294 0.987
Human Mouse Rat Fly
regulation of rna biosynthetic process GO:2001141 213 0.987
Human Mouse Rat Fly
diencephalon development GO:0021536 58 0.986
kidney development GO:0001822 92 0.986
Zebrafish Mouse
neuronal stem cell maintenance GO:0097150 2 0.986
Human Zebrafish
peripheral nervous system development GO:0007422 55 0.985
regulation of mechanoreceptor differentiation GO:0045631 1 0.984
heterocycle metabolic process GO:0046483 290 0.984
Human Mouse Rat Fly
cellular nitrogen compound metabolic process GO:0034641 290 0.984
Human Mouse Rat Fly
cell morphogenesis involved in differentiation GO:0000904 195 0.983
positive regulation of cell proliferation GO:0008284 15 0.983
Human Mouse Rat Fly
neural crest cell migration GO:0001755 42 0.981
locomotion GO:0040011 313 0.979
Human Mouse Worm Fly
regulation of macromolecule metabolic process GO:0060255 317 0.977
Human Mouse Rat Fly
heterocycle biosynthetic process GO:0018130 215 0.976
Human Mouse Rat Fly
cell motility GO:0048870 244 0.975
Human Mouse Fly
embryonic pattern specification GO:0009880 44 0.973
Worm
sensory organ development GO:0007423 393 0.973
Mouse Fly
nitrogen compound metabolic process GO:0006807 319 0.972
Human Mouse Rat Fly
regulation of inner ear receptor cell differentiation GO:2000980 1 0.971
gene expression GO:0010467 252 0.969
Human Mouse Rat Fly
negative regulation of biological process GO:0048519 304 0.968
cell morphogenesis GO:0000902 289 0.968
regulation of cellular biosynthetic process GO:0031326 245 0.967
Human Mouse Rat Fly
positive regulation of biosynthetic process GO:0009891 68 0.967
Human Mouse Rat Fly
epidermal cell differentiation GO:0009913 36 0.965
Mouse
aromatic compound biosynthetic process GO:0019438 217 0.964
Human Mouse Rat Fly
regulation of metabolic process GO:0019222 359 0.962
Human Mouse Rat Fly
sensory organ morphogenesis GO:0090596 200 0.960
Fly
regulation of signal transduction GO:0009966 225 0.959
Mouse Fly
rna biosynthetic process GO:0032774 181 0.957
Human Mouse Rat Fly
stem cell development GO:0048864 82 0.954
Human Zebrafish Mouse Fly
regulation of nucleic acid templated transcription GO:1903506 213 0.954
Human Mouse Rat Fly
system process GO:0003008 185 0.954
Zebrafish Fly
mesoderm morphogenesis GO:0048332 51 0.953
forebrain development GO:0030900 96 0.953
cartilage development involved in endochondral bone morphogenesis GO:0060351 8 0.952
Zebrafish
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.951
Human Mouse Rat Fly
peripheral nervous system neuron differentiation GO:0048934 28 0.949
somite specification GO:0001757 12 0.948
neural crest cell differentiation GO:0014033 72 0.948
cell part morphogenesis GO:0032990 246 0.947
response to organic substance GO:0010033 153 0.944
Human Mouse Rat
anterior posterior pattern specification GO:0009952 152 0.944
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.943
Mouse Fly
pronephros development GO:0048793 69 0.942
Zebrafish
positive regulation of macromolecule metabolic process GO:0010604 93 0.941
Human Mouse Rat Fly
positive regulation of rna biosynthetic process GO:1902680 57 0.937
Human Mouse Rat Fly
regulation of cellular metabolic process GO:0031323 320 0.935
Human Mouse Rat Fly
nucleobase containing compound metabolic process GO:0006139 274 0.935
Human Mouse Rat Fly
neuron development GO:0048666 262 0.928
neural crest cell development GO:0014032 62 0.928
cell projection organization GO:0030030 284 0.923
axon guidance GO:0007411 86 0.923
Fly
cell surface receptor signaling pathway GO:0007166 325 0.919
regulation of rna metabolic process GO:0051252 224 0.917
Human Mouse Rat Fly
hematopoietic progenitor cell differentiation GO:0002244 23 0.916
Mouse
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.914
Human Mouse Rat Fly
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.911
Mouse
inner ear development GO:0048839 126 0.909
Mouse
neuron projection morphogenesis GO:0048812 161 0.908
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.908
Mouse
heterophilic cell cell adhesion via plasma membrane cell adhesion molecules GO:0007157 2 0.906
Fly
organic cyclic compound biosynthetic process GO:1901362 223 0.904
Human Mouse Rat Fly
transcription from rna polymerase ii promoter GO:0006366 80 0.903
Human Mouse Rat Fly
epidermis development GO:0008544 48 0.901
Mouse
cellular biosynthetic process GO:0044249 286 0.897
Human Mouse Rat Fly
organic substance biosynthetic process GO:1901576 289 0.896
Human Mouse Rat Fly
cilium assembly GO:0042384 58 0.895
negative regulation of biosynthetic process GO:0009890 55 0.894
Mouse
negative regulation of cellular process GO:0048523 283 0.885
cell fate specification GO:0001708 68 0.885
negative regulation of blood vessel endothelial cell migration GO:0043537 1 0.885
Human
positive regulation of gene expression GO:0010628 71 0.881
Human Mouse Rat Fly
cellular nitrogen compound biosynthetic process GO:0044271 218 0.879
Human Mouse Rat Fly
mesenchyme development GO:0060485 127 0.878
Human Mouse
cilium organization GO:0044782 71 0.872
somite development GO:0061053 96 0.867
cell proliferation involved in heart morphogenesis GO:0061323 2 0.866
Rat
hair cell differentiation GO:0035315 32 0.861
Mouse
regulation of stem cell differentiation GO:2000736 4 0.858
Human Mouse Fly
specification of symmetry GO:0009799 204 0.858
establishment of localization GO:0051234 244 0.846
neuron fate commitment GO:0048663 26 0.846
Mouse
positive regulation of nucleic acid templated transcription GO:1903508 57 0.844
Human Mouse Rat Fly
developmental growth involved in morphogenesis GO:0060560 86 0.839
Mouse
neuron projection guidance GO:0097485 86 0.837
Fly
epithelial cell differentiation GO:0030855 116 0.837
Mouse Rat Fly
ventral spinal cord interneuron differentiation GO:0021514 12 0.833
digestive tract development GO:0048565 265 0.833
positive regulation of cellular biosynthetic process GO:0031328 68 0.832
Human Mouse Rat Fly
rhombomere development GO:0021546 19 0.831
Zebrafish
ventral spinal cord interneuron fate commitment GO:0060579 3 0.830
patterning of lymph vessels GO:0060854 1 0.829
chemotaxis GO:0006935 104 0.818
Human Fly
regulation of multicellular organismal development GO:2000026 223 0.818
rhombomere boundary formation GO:0021654 10 0.805
Zebrafish
cellular component movement GO:0006928 335 0.805
Human Mouse Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.803
Human Mouse Rat Fly
developmental process involved in reproduction GO:0003006 27 0.800
Mouse Worm Fly
oligodendrocyte development GO:0014003 7 0.792
Zebrafish
hypochord development GO:0055016 3 0.790
venous endothelial cell migration involved in lymph vessel development GO:0060855 4 0.790
regionalization GO:0003002 274 0.780
somatic motor neuron differentiation GO:0021523 5 0.777
skin development GO:0043588 54 0.775
Mouse
response to hormone GO:0009725 48 0.772
Human Rat
stem cell fate commitment GO:0048865 1 0.766
Fly
gastrulation GO:0007369 208 0.766
larval development GO:0002164 2 0.763
Worm Fly
hemopoiesis GO:0030097 183 0.759
Mouse Fly
ventral spinal cord interneuron specification GO:0021521 3 0.757
eye development GO:0001654 277 0.753
Fly
response to external stimulus GO:0009605 264 0.751
Human Rat Fly
kidney epithelium development GO:0072073 23 0.746
Mouse
cell migration GO:0016477 237 0.745
Human Mouse Fly
blood vessel development GO:0001568 246 0.740
Human Zebrafish Mouse
glial cell differentiation GO:0010001 42 0.735
pituitary gland development GO:0021983 16 0.735
embryonic organ morphogenesis GO:0048562 274 0.733
Mouse
smoothened signaling pathway GO:0007224 30 0.725
stem cell maintenance GO:0019827 4 0.724
Human Zebrafish Fly
spinal cord motor neuron differentiation GO:0021522 26 0.721
negative regulation of epithelial cell migration GO:0010633 1 0.719
Human
glomerulus vasculature development GO:0072012 2 0.717
Mouse
foregut morphogenesis GO:0007440 4 0.712
Mouse Fly
urogenital system development GO:0001655 97 0.710
Zebrafish Mouse Fly
nucleobase containing compound biosynthetic process GO:0034654 205 0.709
Human Mouse Rat Fly
neural tube development GO:0021915 62 0.707
Mouse
regulation of cell development GO:0060284 100 0.701
determination of bilateral symmetry GO:0009855 204 0.700
mesoderm development GO:0007498 88 0.696
proximal tubule development GO:0072014 3 0.693
brain development GO:0007420 293 0.686
auditory receptor cell fate commitment GO:0009912 4 0.685
Mouse
camera type eye development GO:0043010 222 0.681
immune system development GO:0002520 191 0.678
Mouse Fly
blood vessel endothelial cell proliferation involved in sprouting angiogenesis GO:0002043 4 0.676
blood vessel morphogenesis GO:0048514 216 0.673
Human Zebrafish Mouse
mechanoreceptor differentiation GO:0042490 37 0.668
Mouse
ameboidal type cell migration GO:0001667 143 0.667
Human Fly
ear development GO:0043583 127 0.665
Mouse
neuroblast proliferation GO:0007405 2 0.664
Rat
regulation of cell communication GO:0010646 232 0.661
Mouse Fly
mesenchymal cell differentiation GO:0048762 87 0.661
Human Mouse
vasculature development GO:0001944 278 0.656
Human Zebrafish Mouse
muscle cell differentiation GO:0042692 139 0.652
Human Mouse Fly
regulation of multicellular organismal process GO:0051239 277 0.647
peripheral nervous system neuron development GO:0048935 22 0.645
muscle cell fate determination GO:0007521 1 0.645
Fly
regulation of axonogenesis GO:0050770 32 0.643
cellular response to endogenous stimulus GO:0071495 68 0.642
Human
reproduction GO:0000003 40 0.635
Rat Worm Fly
taxis GO:0042330 109 0.632
Human Fly
astrocyte differentiation GO:0048708 1 0.626
Mouse Rat
glial cell fate commitment GO:0021781 6 0.626
Fly
adenohypophysis development GO:0021984 15 0.619
gland development GO:0048732 143 0.617
Zebrafish Mouse Fly
notch signaling pathway GO:0007219 35 0.617
enzyme linked receptor protein signaling pathway GO:0007167 106 0.609
Mouse
negative regulation of endothelial cell migration GO:0010596 1 0.607
Human
negative regulation of cellular biosynthetic process GO:0031327 55 0.600
Mouse
cell projection assembly GO:0030031 64 0.596
Fly
regulation of retina development in camera type eye GO:1902866 2 0.590
regulation of locomotion GO:0040012 55 0.582
Human Mouse
mitotic cell cycle GO:0000278 64 0.581
Fly
response to endogenous stimulus GO:0009719 83 0.580
Human Mouse Rat
ensheathment of neurons GO:0007272 18 0.580
nephron morphogenesis GO:0072028 2 0.577
eye morphogenesis GO:0048592 144 0.573
Fly
cellular response to organic substance GO:0071310 105 0.573
Human
positive regulation of transcription dna templated GO:0045893 57 0.572
Human Mouse Rat Fly
otolith morphogenesis GO:0032474 8 0.569
cellular component morphogenesis GO:0032989 336 0.568
regulation of stem cell proliferation GO:0072091 2 0.568
Rat
embryonic viscerocranium morphogenesis GO:0048703 52 0.560
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.549
Mouse
axonogenesis GO:0007409 152 0.545
rhombomere morphogenesis GO:0021593 17 0.541
Zebrafish
negative regulation of neurogenesis GO:0050768 20 0.541
respiratory system development GO:0060541 5 0.529
Mouse Fly
wnt signaling pathway GO:0016055 80 0.527
Mouse
cell projection morphogenesis GO:0048858 244 0.525
transcription dna templated GO:0006351 181 0.523
Human Mouse Rat Fly
auditory receptor cell fate determination GO:0042668 2 0.516
taste bud formation GO:0061195 3 0.516
branching morphogenesis of an epithelial tube GO:0048754 15 0.509
Mouse
bone morphogenesis GO:0060349 11 0.498
Zebrafish
regulation of multicellular organism growth GO:0040014 4 0.496
regulation of neuron differentiation GO:0045664 56 0.495
Mouse Rat Fly
hematopoietic stem cell differentiation GO:0060218 20 0.495
atrial ventricular junction remodeling GO:0003294 2 0.494
regulation of localization GO:0032879 104 0.492
regulation of notch signaling pathway GO:0008593 16 0.491
Fly
digestive system development GO:0055123 289 0.488
steroid hormone mediated signaling pathway GO:0043401 9 0.482
segment specification GO:0007379 12 0.478
nephron epithelium morphogenesis GO:0072088 1 0.473
positive regulation of epithelial cell differentiation GO:0030858 2 0.470
Mouse Rat
endocrine system development GO:0035270 65 0.464
negative regulation of signal transduction GO:0009968 94 0.449
Mouse
radial glial cell differentiation GO:0060019 2 0.444
spinal cord dorsal ventral patterning GO:0021513 5 0.442
axon ensheathment GO:0008366 18 0.441
epithelial cell morphogenesis GO:0003382 2 0.440
kidney vasculature development GO:0061440 2 0.439
Mouse
central nervous system neuron differentiation GO:0021953 74 0.431
stem cell differentiation GO:0048863 117 0.430
Human Zebrafish Mouse Fly
semicircular canal morphogenesis GO:0048752 18 0.428
cell differentiation involved in kidney development GO:0061005 13 0.425
Mouse
camera type eye morphogenesis GO:0048593 108 0.423
stem cell proliferation GO:0072089 4 0.423
Rat
regulation of response to stimulus GO:0048583 269 0.414
Human Mouse Fly
canonical wnt signaling pathway GO:0060070 48 0.414
Mouse
regulation of cell differentiation GO:0045595 142 0.414
negative regulation of rna biosynthetic process GO:1902679 45 0.412
Mouse
dorsal ventral pattern formation GO:0009953 125 0.407
Fly
endodermal cell fate specification GO:0001714 17 0.406
protein localization GO:0008104 40 0.405
Mouse
morphogenesis of a branching structure GO:0001763 21 0.404
Mouse
apoptotic process GO:0006915 116 0.404
Human Mouse
endoderm development GO:0007492 49 0.403
compound eye development GO:0048749 2 0.402
Fly
peripheral nervous system neuron axonogenesis GO:0048936 13 0.398
nephron tubule morphogenesis GO:0072078 1 0.395
regulation of signaling GO:0023051 235 0.391
Mouse Fly
negative regulation of cell differentiation GO:0045596 46 0.390
thyroid gland development GO:0030878 12 0.386
pigment cell differentiation GO:0050931 38 0.386
neuron differentiation GO:0030182 353 0.381
inner ear receptor cell fate commitment GO:0060120 4 0.381
Mouse
morphogenesis of an epithelial fold GO:0060571 1 0.380
renal system vasculature development GO:0061437 2 0.379
Mouse
pancreatic a cell development GO:0003322 2 0.374
cellular response to chemical stimulus GO:0070887 157 0.373
Human Mouse
epithelial tube formation GO:0072175 19 0.373
aorta development GO:0035904 4 0.364
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.359
Human Mouse Rat Fly
positive regulation of programmed cell death GO:0043068 29 0.358
Mouse
axial mesoderm development GO:0048318 10 0.355
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.355
behavior GO:0007610 74 0.353
Human Worm Fly
embryonic limb morphogenesis GO:0030326 2 0.353
Mouse
lateral inhibition GO:0046331 1 0.349
Fly
digestive tract morphogenesis GO:0048546 231 0.349
neuroepithelial cell differentiation GO:0060563 26 0.344
auditory receptor cell differentiation GO:0042491 15 0.341
Mouse
regulation of cell projection assembly GO:0060491 4 0.337
Fly
cell cycle GO:0007049 93 0.335
Worm Fly
regulation of growth GO:0040008 42 0.334
Mouse Fly
rhombomere formation GO:0021594 12 0.331
Zebrafish
negative regulation of macromolecule metabolic process GO:0010605 76 0.331
Mouse Fly
retinal rod cell development GO:0046548 4 0.327
floor plate development GO:0033504 15 0.326
developmental pigmentation GO:0048066 48 0.321
regulation of cellular protein metabolic process GO:0032268 52 0.318
otic vesicle development GO:0071599 42 0.315
axon development GO:0061564 166 0.305
invagination involved in gastrulation with mouth forming second GO:0055109 1 0.304
hematopoietic or lymphoid organ development GO:0048534 191 0.301
Mouse Fly
aging GO:0007568 2 0.299
Worm Fly
epithelial tube morphogenesis GO:0060562 148 0.299
Mouse Fly
regulation of neural precursor cell proliferation GO:2000177 3 0.297
Rat
melanocyte differentiation GO:0030318 26 0.297
auditory receptor cell development GO:0060117 8 0.294
skeletal system development GO:0001501 181 0.294
Zebrafish
renal system development GO:0072001 94 0.294
Zebrafish Mouse Fly
death GO:0016265 121 0.293
Human Mouse
central nervous system myelination GO:0022010 2 0.290
regulation of glial cell differentiation GO:0045685 4 0.287
Mouse Rat
oligodendrocyte differentiation GO:0048709 23 0.286
Zebrafish Mouse Rat
regulation of endodermal cell fate specification GO:0042663 15 0.286
protein modification process GO:0036211 100 0.282
Fly
photoreceptor cell fate specification GO:0043704 1 0.279
embryonic skeletal system development GO:0048706 97 0.278
positive regulation of mesoderm development GO:2000382 1 0.276
rhombomere 5 development GO:0021571 4 0.275
response to oxygen containing compound GO:1901700 55 0.274
Mouse Rat
neural tube patterning GO:0021532 33 0.272
appendage development GO:0048736 80 0.272
Mouse Fly
response to lipid GO:0033993 60 0.271
Rat
cellular protein metabolic process GO:0044267 129 0.269
Fly
keratinocyte differentiation GO:0030216 0 0.267
Mouse
photoreceptor cell differentiation GO:0046530 55 0.267
Mouse Fly
regulation of apoptotic process GO:0042981 98 0.266
Human Mouse
neurological system process GO:0050877 62 0.265
Fly
regulation of cell death GO:0010941 103 0.263
Human Mouse
localization of cell GO:0051674 244 0.263
Human Mouse Fly
response to chemical GO:0042221 320 0.263
Human Mouse Rat Fly
regulation of epithelial cell proliferation GO:0050678 3 0.260
Mouse
inner ear receptor cell differentiation GO:0060113 29 0.259
Mouse
tongue morphogenesis GO:0043587 3 0.258
regulation of cell fate commitment GO:0010453 22 0.257
regulation of cell proliferation involved in heart morphogenesis GO:2000136 2 0.256
Mouse Rat
negative regulation of transcription dna templated GO:0045892 45 0.256
Mouse
forebrain neuron differentiation GO:0021879 14 0.250
cartilage development GO:0051216 96 0.250
Zebrafish
endochondral bone morphogenesis GO:0060350 8 0.248
Zebrafish
regulation of embryonic development GO:0045995 47 0.247
bone development GO:0060348 14 0.246
Zebrafish
somitogenesis GO:0001756 87 0.245
regulation of anatomical structure morphogenesis GO:0022603 130 0.239
aorta morphogenesis GO:0035909 3 0.239
germ line stem cell maintenance GO:0030718 2 0.231
Fly
nephron development GO:0072006 31 0.228
Mouse
negative regulation of metabolic process GO:0009892 86 0.228
Mouse Fly
cellular response to hormone stimulus GO:0032870 39 0.224
Human
mesendoderm development GO:0048382 10 0.223
axon ensheathment in central nervous system GO:0032291 2 0.223
distal tubule development GO:0072017 1 0.223
Mouse
negative regulation of developmental process GO:0051093 65 0.219
negative regulation of cell communication GO:0010648 96 0.218
Mouse
auditory receptor cell morphogenesis GO:0002093 4 0.210
chemical homeostasis GO:0048878 49 0.210
forebrain generation of neurons GO:0021872 14 0.207
regulation of neurogenesis GO:0050767 87 0.207
regulation of cell proliferation GO:0042127 37 0.206
Human Mouse Rat Worm Fly
epithelial cell development GO:0002064 42 0.205
Mouse Fly
immune system process GO:0002376 241 0.205
Mouse Fly
regulation of oligodendrocyte differentiation GO:0048713 1 0.205
Mouse
protein metabolic process GO:0019538 183 0.204
Fly
lens development in camera type eye GO:0002088 22 0.204
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.203
Mouse
developmental growth GO:0048589 166 0.201
Zebrafish Mouse Rat
reproductive process GO:0022414 40 0.199
Mouse Rat Worm Fly
bmp signaling pathway GO:0030509 52 0.197
Mouse
spinal cord development GO:0021510 46 0.197
septum transversum development GO:0003343 4 0.196
negative regulation of multicellular organismal process GO:0051241 69 0.194
positive regulation of cell cycle GO:0045787 3 0.194
Fly
response to steroid hormone GO:0048545 35 0.193
Rat
mesodermal cell fate commitment GO:0001710 14 0.190
positive regulation of apoptotic process GO:0043065 29 0.190
Mouse
embryonic digestive tract morphogenesis GO:0048557 3 0.189
regulation of programmed cell death GO:0043067 101 0.187
Human Mouse
neuron fate specification GO:0048665 20 0.186
inner ear receptor cell development GO:0060119 20 0.186
cellular response to organic cyclic compound GO:0071407 38 0.186
ear morphogenesis GO:0042471 64 0.184
epidermal cell fate specification GO:0009957 4 0.183
inner ear receptor stereocilium organization GO:0060122 8 0.183
central nervous system development GO:0007417 387 0.182
retina development in camera type eye GO:0060041 146 0.180
hormone transport GO:0009914 2 0.180
endocardium formation GO:0060214 1 0.179
cellular ketone metabolic process GO:0042180 11 0.179
atrioventricular valve formation GO:0003190 3 0.175
Human
regulation of cell division GO:0051302 12 0.175
Worm
regulation of cellular component organization GO:0051128 86 0.171
medulla oblongata development GO:0021550 4 0.171
regulation of nervous system development GO:0051960 90 0.165
male gamete generation GO:0048232 7 0.164
Rat
regulation of cell motility GO:2000145 46 0.162
Human Mouse
regulation of cell cycle GO:0051726 52 0.158
Worm Fly
liver development GO:0001889 96 0.155
Zebrafish Mouse
negative regulation of mitosis GO:0045839 3 0.154
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.154
mesenchymal cell development GO:0014031 78 0.151
Human Mouse
regulation of membrane potential GO:0042391 23 0.151
embryonic eye morphogenesis GO:0048048 30 0.149
regulation of bmp signaling pathway GO:0030510 39 0.149
Mouse
mesodermal cell fate specification GO:0007501 12 0.147
morphogenesis of embryonic epithelium GO:0016331 30 0.147
regulation of myelination GO:0031641 1 0.146
axis elongation GO:0003401 31 0.145
negative regulation of protein metabolic process GO:0051248 16 0.142
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.142
Fly
negative regulation of nuclear division GO:0051784 3 0.141
response to peptide GO:1901652 6 0.141
Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.140
Human Mouse
circulatory system process GO:0003013 87 0.137
Zebrafish
pharyngeal system development GO:0060037 18 0.137
heart jogging GO:0003146 40 0.137
determination of left right symmetry GO:0007368 179 0.137
establishment of cell polarity GO:0030010 18 0.135
cell cell adhesion involved in gastrulation GO:0070586 4 0.134
glial cell development GO:0021782 20 0.134
Zebrafish
gliogenesis GO:0042063 45 0.132
growth GO:0040007 174 0.132
Zebrafish Mouse Rat Fly
regulation of eye photoreceptor cell development GO:0042478 2 0.132
Fly
regulation of neural retina development GO:0061074 2 0.130
positive regulation of gastrulation GO:2000543 2 0.130
regulation of epidermis development GO:0045682 2 0.130
Mouse
regulation of hormone levels GO:0010817 21 0.130
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.130
Mouse
spermatogenesis GO:0007283 7 0.128
Rat
forebrain neuron development GO:0021884 7 0.128
glial cell fate determination GO:0007403 1 0.128
Fly
cell cell adhesion involved in mesendodermal cell migration GO:0003370 1 0.127
action potential GO:0001508 19 0.127
carboxylic acid metabolic process GO:0019752 22 0.125
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.124
Mouse
neuronal action potential GO:0019228 18 0.124
regulation of skeletal muscle fiber development GO:0048742 2 0.124
Human
regulation of cellular component movement GO:0051270 55 0.123
Human Mouse
tube morphogenesis GO:0035239 349 0.123
head development GO:0060322 303 0.121
renal tubule morphogenesis GO:0061333 1 0.120
Fly
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.120
organelle fission GO:0048285 23 0.120
Worm
negative regulation of neuron differentiation GO:0045665 10 0.120
Mouse Rat Fly
regulation of endodermal cell differentiation GO:1903224 15 0.119
negative regulation of gene expression GO:0010629 65 0.119
Mouse Fly
macromolecular complex subunit organization GO:0043933 74 0.119
Fly
autonomic nervous system development GO:0048483 19 0.118
positive regulation of cell fate commitment GO:0010455 1 0.118
regulation of cellular amino acid metabolic process GO:0006521 0 0.116
nephron epithelium development GO:0072009 16 0.116
Mouse
apoptotic process involved in morphogenesis GO:0060561 2 0.116
Mouse
transport GO:0006810 220 0.115
embryonic skeletal joint development GO:0072498 3 0.115
germ cell development GO:0007281 22 0.114
Fly
cell cycle process GO:0022402 53 0.113
Worm Fly
epithelial cell differentiation involved in kidney development GO:0035850 13 0.112
Mouse
hormone biosynthetic process GO:0042446 3 0.112
regulation of wnt signaling pathway GO:0030111 53 0.111
Mouse
regulation of biological quality GO:0065008 263 0.110
Zebrafish Fly
regulation of protein ubiquitination GO:0031396 3 0.109
otic vesicle formation GO:0030916 27 0.108
regulation of mitotic cell cycle GO:0007346 25 0.107
Fly
mesodermal cell differentiation GO:0048333 21 0.106
multicellular organismal signaling GO:0035637 22 0.106
otic vesicle morphogenesis GO:0071600 34 0.105
developmental programmed cell death GO:0010623 4 0.105
Mouse
intermediate mesoderm development GO:0048389 2 0.103
single organism localization GO:1902578 225 0.102
Mouse
neuroblast differentiation GO:0014016 1 0.102
Fly
abducens nucleus development GO:0021742 2 0.101
negative regulation of cell development GO:0010721 26 0.101
lymphangiogenesis GO:0001946 25 0.099
Zebrafish
cellular component assembly involved in morphogenesis GO:0010927 107 0.098
Fly
neuroblast fate commitment GO:0014017 1 0.097
Fly
regulation of cell growth GO:0001558 29 0.096
cell migration involved in heart development GO:0060973 22 0.095
Mouse
regulation of developmental process GO:0050793 247 0.095
formation of anatomical boundary GO:0048859 14 0.093
Zebrafish Fly
regulation of cell fate specification GO:0042659 20 0.092
cellular localization GO:0051641 97 0.089
Mouse
nerve development GO:0021675 45 0.088
rostrocaudal neural tube patterning GO:0021903 29 0.088
heart valve formation GO:0003188 4 0.087
Human
mesoderm formation GO:0001707 43 0.087
pancreas development GO:0031016 84 0.086
axial mesoderm morphogenesis GO:0048319 8 0.086
heart morphogenesis GO:0003007 156 0.085
Human Mouse Rat
renal tubule development GO:0061326 5 0.085
Mouse Fly
telencephalon development GO:0021537 14 0.085
myotube cell development GO:0014904 35 0.084
Human
skeletal muscle tissue development GO:0007519 67 0.084
Human Mouse Fly
inner ear morphogenesis GO:0042472 63 0.084
oxoacid metabolic process GO:0043436 31 0.083
neuroblast fate determination GO:0007400 1 0.083
Fly
forebrain regionalization GO:0021871 4 0.083
myelination GO:0042552 18 0.083
cell type specific apoptotic process GO:0097285 22 0.081
regulation of collateral sprouting GO:0048670 7 0.081
multi organism process GO:0051704 134 0.081
Rat Worm Fly
regulation of cell matrix adhesion GO:0001952 1 0.081
hindbrain morphogenesis GO:0021575 22 0.080
multicellular organism reproduction GO:0032504 35 0.079
Rat Worm Fly
negative regulation of nervous system development GO:0051961 22 0.078

notch1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.640
Human
kidney disease DOID:557 0 0.088
urinary system disease DOID:18 0 0.088