Danio rerio

0 known processes

pola1

polymerase (DNA directed), alpha 1

(Aliases: cb678,pola)

pola1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
meiotic nuclear division GO:0007126 4 0.740
cellular macromolecule biosynthetic process GO:0034645 224 0.697
Human Yeast Mouse
meiosis i GO:0007127 1 0.536
embryo development ending in birth or egg hatching GO:0009792 271 0.462
Worm
larval development GO:0002164 2 0.430
organelle organization GO:0006996 227 0.343
cellular biosynthetic process GO:0044249 286 0.278
Human Yeast Mouse
cell cycle process GO:0022402 53 0.275
Yeast
dna metabolic process GO:0006259 27 0.266
Human Yeast Mouse
cellular nitrogen compound metabolic process GO:0034641 290 0.257
Human Yeast Mouse
cellular component assembly GO:0022607 170 0.251
double strand break repair GO:0006302 3 0.237
Human Yeast
aromatic compound biosynthetic process GO:0019438 217 0.228
Human Yeast Mouse
locomotion GO:0040011 313 0.223
cell cycle GO:0007049 93 0.222
Yeast
protein acetylation GO:0006473 2 0.200
male meiosis GO:0007140 2 0.177
organic cyclic compound biosynthetic process GO:1901362 223 0.173
Human Yeast Mouse
organelle fission GO:0048285 23 0.169
hemopoiesis GO:0030097 183 0.166
maintenance of dna repeat elements GO:0043570 2 0.163
regulation of multicellular organism growth GO:0040014 4 0.159
reproduction GO:0000003 40 0.148
Yeast Worm
negative regulation of cellular process GO:0048523 283 0.146
heterocycle metabolic process GO:0046483 290 0.145
Human Yeast Mouse
cell motility GO:0048870 244 0.144
nitrogen compound metabolic process GO:0006807 319 0.142
Human Yeast Mouse
regulation of metabolic process GO:0019222 359 0.140
heterocycle biosynthetic process GO:0018130 215 0.138
Human Yeast Mouse
biosynthetic process GO:0009058 294 0.136
Human Yeast Mouse
nucleobase containing compound metabolic process GO:0006139 274 0.132
Human Yeast Mouse
single organism organelle organization GO:1902589 199 0.124
mitotic dna integrity checkpoint GO:0044774 4 0.113
reciprocal meiotic recombination GO:0007131 1 0.112
meiotic cell cycle process GO:1903046 3 0.107
Yeast
meiotic chromosome segregation GO:0045132 3 0.103
cellular aromatic compound metabolic process GO:0006725 295 0.103
Human Yeast Mouse
transport GO:0006810 220 0.103
somatic cell dna recombination GO:0016444 1 0.100
microtubule based process GO:0007017 60 0.100
protein acylation GO:0043543 3 0.099
immunoglobulin mediated immune response GO:0016064 3 0.099
b cell mediated immunity GO:0019724 3 0.098
dna modification GO:0006304 8 0.098
double strand break repair via nonhomologous end joining GO:0006303 1 0.097
Human
chromosome organization GO:0051276 31 0.096
organic substance biosynthetic process GO:1901576 289 0.096
Human Yeast Mouse
nucleobase containing compound biosynthetic process GO:0034654 205 0.090
Human Yeast Mouse
rna metabolic process GO:0016070 219 0.090
Human
dna methylation GO:0006306 8 0.089
gene expression GO:0010467 252 0.087
sister chromatid cohesion GO:0007062 2 0.087
dna biosynthetic process GO:0071897 3 0.085
Human Yeast Mouse
dna alkylation GO:0006305 8 0.080
mitotic cell cycle GO:0000278 64 0.080
developmental process involved in reproduction GO:0003006 27 0.077
organic cyclic compound metabolic process GO:1901360 301 0.076
Human Yeast Mouse
multicellular organism growth GO:0035264 4 0.075
digestive tract development GO:0048565 265 0.074
nucleic acid templated transcription GO:0097659 181 0.074
non recombinational repair GO:0000726 2 0.073
Human
nuclear division GO:0000280 23 0.072
internal protein amino acid acetylation GO:0006475 2 0.071
positive regulation of chromatin modification GO:1903310 1 0.071
immune system process GO:0002376 241 0.071
mitotic recombination GO:0006312 2 0.070
mitotic g2 dna damage checkpoint GO:0007095 3 0.070
phosphorus metabolic process GO:0006793 109 0.069
nucleic acid metabolic process GO:0090304 244 0.067
Human Yeast Mouse
internal peptidyl lysine acetylation GO:0018393 2 0.066
peptidyl lysine acetylation GO:0018394 2 0.065
multi organism process GO:0051704 134 0.064
Worm
negative regulation of histone methylation GO:0031061 1 0.063
microtubule cytoskeleton organization GO:0000226 33 0.063
cellular nitrogen compound biosynthetic process GO:0044271 218 0.062
Human Yeast Mouse
cellular component biogenesis GO:0044085 178 0.062
chromosome organization involved in meiosis GO:0070192 1 0.061
digestive system development GO:0055123 289 0.059
eye development GO:0001654 277 0.058
mitotic cell cycle process GO:1903047 48 0.058
regulation of protein transport GO:0051223 3 0.058
reciprocal dna recombination GO:0035825 1 0.054
mitotic g2 m transition checkpoint GO:0044818 3 0.054
regulation of establishment of protein localization GO:0070201 4 0.053
establishment of localization GO:0051234 244 0.053
Worm
response to stress GO:0006950 263 0.052
Human Yeast
camera type eye development GO:0043010 222 0.050
regulation of gene expression epigenetic GO:0040029 11 0.050
regulation of rna metabolic process GO:0051252 224 0.050
chromatin modification GO:0016568 21 0.049
macromolecule biosynthetic process GO:0009059 227 0.049
Human Yeast Mouse
regulation of cellular ketone metabolic process GO:0010565 7 0.049
response to amino acid GO:0043200 2 0.049
retina development in camera type eye GO:0060041 146 0.048
regulation of biosynthetic process GO:0009889 250 0.048
regulation of cellular biosynthetic process GO:0031326 245 0.047
phosphate containing compound metabolic process GO:0006796 108 0.046
cell migration GO:0016477 237 0.046
regulation of histone h3 k9 methylation GO:0051570 2 0.045
developmental growth GO:0048589 166 0.045
regulation of mitotic cell cycle GO:0007346 25 0.045
macromolecule modification GO:0043412 111 0.045
single organism metabolic process GO:0044710 217 0.045
Human Yeast
response to uv GO:0009411 3 0.044
regulation of primary metabolic process GO:0080090 311 0.044
protein complex subunit organization GO:0071822 46 0.044
cytoskeleton organization GO:0007010 96 0.043
localization of cell GO:0051674 244 0.042
immune system development GO:0002520 191 0.042
regulation of nucleic acid templated transcription GO:1903506 213 0.042
ribonucleoside monophosphate catabolic process GO:0009158 4 0.041
positive regulation of histone modification GO:0031058 1 0.041
mitotic nuclear division GO:0007067 18 0.040
dna methylation or demethylation GO:0044728 8 0.039
regulation of cellular metabolic process GO:0031323 320 0.038
cellular protein modification process GO:0006464 100 0.038
cellular component movement GO:0006928 335 0.038
cell morphogenesis GO:0000902 289 0.038
regulation of macromolecule metabolic process GO:0060255 317 0.037
cellular amine metabolic process GO:0044106 2 0.037
negative regulation of dna metabolic process GO:0051053 4 0.037
regulation of transcription dna templated GO:0006355 213 0.037
response to organic substance GO:0010033 153 0.036
regulation of meiotic cell cycle GO:0051445 1 0.036
nucleoside monophosphate catabolic process GO:0009125 4 0.034
g2 dna damage checkpoint GO:0031572 3 0.034
methylation GO:0032259 22 0.033
leukocyte proliferation GO:0070661 1 0.033
cellular protein metabolic process GO:0044267 129 0.032
negative regulation of chromosome organization GO:2001251 1 0.031
regulation of dna recombination GO:0000018 2 0.031
regulation of developmental growth GO:0048638 38 0.031
atp catabolic process GO:0006200 4 0.031
cellular macromolecule metabolic process GO:0044260 391 0.030
Human Yeast Mouse
single organism reproductive process GO:0044702 40 0.030
Worm
regulation of cytoplasmic transport GO:1903649 4 0.030
negative regulation of nucleic acid templated transcription GO:1903507 45 0.029
double strand break repair via homologous recombination GO:0000724 1 0.029
centrosome organization GO:0051297 1 0.029
regulation of protein import into nucleus GO:0042306 2 0.028
sensory organ development GO:0007423 393 0.028
protein metabolic process GO:0019538 183 0.027
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.027
sex differentiation GO:0007548 5 0.027
amine metabolic process GO:0009308 2 0.027
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.027
chromatin organization GO:0006325 22 0.027
response to light stimulus GO:0009416 46 0.026
negative regulation of nuclear division GO:0051784 3 0.026
positive regulation of cell cycle GO:0045787 3 0.026
regulation of gene expression GO:0010468 265 0.026
immunoglobulin production GO:0002377 1 0.026
regulation of cellular amino acid metabolic process GO:0006521 0 0.026
regulation of protein catabolic process GO:0042176 1 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.026
cytokinesis GO:0000910 3 0.025
regulation of programmed cell death GO:0043067 101 0.025
regulation of cell cycle GO:0051726 52 0.025
reproductive structure development GO:0048608 5 0.025
meiotic cell cycle GO:0051321 5 0.025
Yeast
response to endogenous stimulus GO:0009719 83 0.025
establishment of protein localization to organelle GO:0072594 4 0.024
maintenance of location GO:0051235 4 0.024
lipid catabolic process GO:0016042 4 0.024
microtubule polymerization GO:0046785 2 0.024
regulation of developmental process GO:0050793 247 0.024
spindle assembly GO:0051225 2 0.024
macromolecular complex assembly GO:0065003 35 0.024
regulation of intracellular protein transport GO:0033157 3 0.024
blood vessel development GO:0001568 246 0.023
chromosome segregation GO:0007059 12 0.023
intracellular signal transduction GO:0035556 85 0.023
mitotic dna damage checkpoint GO:0044773 4 0.023
b cell activation GO:0042113 2 0.023
dna catabolic process GO:0006308 1 0.023
regulation of cell cycle process GO:0010564 20 0.023
negative regulation of biological process GO:0048519 304 0.022
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.022
protein modification process GO:0036211 100 0.022
fertilization GO:0009566 3 0.022
Worm
regulation of histone methylation GO:0031060 3 0.022
rna biosynthetic process GO:0032774 181 0.022
Human
response to radiation GO:0009314 51 0.022
retina morphogenesis in camera type eye GO:0060042 79 0.022
heart development GO:0007507 313 0.021
regulation of nitrogen compound metabolic process GO:0051171 251 0.021
dna methylation on cytosine GO:0032776 3 0.021
cellular amino acid metabolic process GO:0006520 7 0.021
carbohydrate derivative metabolic process GO:1901135 61 0.021
programmed cell death GO:0012501 119 0.020
organonitrogen compound metabolic process GO:1901564 74 0.020
gene silencing GO:0016458 4 0.020
production of molecular mediator of immune response GO:0002440 2 0.020
oxoacid metabolic process GO:0043436 31 0.020
protein complex biogenesis GO:0070271 30 0.020
regulation of mitosis GO:0007088 9 0.020
spermatid differentiation GO:0048515 2 0.019
pyrimidine containing compound biosynthetic process GO:0072528 2 0.019
negative regulation of gene expression GO:0010629 65 0.019
regulation of gene silencing GO:0060968 1 0.019
reproductive process GO:0022414 40 0.019
Worm
growth GO:0040007 174 0.019
negative regulation of transcription dna templated GO:0045892 45 0.019
regulation of dna methylation GO:0044030 5 0.019
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.019
protein polymerization GO:0051258 4 0.019
nuclear transport GO:0051169 4 0.019
cell proliferation GO:0008283 80 0.018
Human
purine nucleoside monophosphate catabolic process GO:0009128 4 0.018
regulation of microtubule cytoskeleton organization GO:0070507 3 0.018
regulation of protein targeting GO:1903533 2 0.018
tube morphogenesis GO:0035239 349 0.018
rna transport GO:0050658 2 0.018
peptidyl serine phosphorylation GO:0018105 1 0.018
sex determination GO:0007530 1 0.017
regulation of protein metabolic process GO:0051246 56 0.017
carboxylic acid metabolic process GO:0019752 22 0.017
cellular macromolecular complex assembly GO:0034622 24 0.017
protein complex assembly GO:0006461 30 0.017
g2 m transition of mitotic cell cycle GO:0000086 4 0.017
positive regulation of biological process GO:0048518 253 0.017
cellular ketone metabolic process GO:0042180 11 0.016
sister chromatid segregation GO:0000819 6 0.016
protein import GO:0017038 3 0.016
negative regulation of metabolic process GO:0009892 86 0.016
regulation of signaling GO:0023051 235 0.016
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.016
dna repair GO:0006281 6 0.016
Human Yeast
negative regulation of histone modification GO:0031057 1 0.016
pyrimidine containing compound metabolic process GO:0072527 3 0.016
regulation of stem cell proliferation GO:0072091 2 0.016
phosphorylation GO:0016310 69 0.016
vasculature development GO:0001944 278 0.016
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.016
cellular response to external stimulus GO:0071496 2 0.016
positive regulation of cellular amine metabolic process GO:0033240 0 0.015
regulation of dna replication GO:0006275 3 0.015
negative regulation of intracellular signal transduction GO:1902532 22 0.015
posttranscriptional regulation of gene expression GO:0010608 14 0.015
positive regulation of dna metabolic process GO:0051054 1 0.015
peptidyl serine modification GO:0018209 2 0.015
single fertilization GO:0007338 3 0.015
Worm
regulation of apoptotic process GO:0042981 98 0.015
cell cycle g2 m phase transition GO:0044839 4 0.015
positive regulation of rna biosynthetic process GO:1902680 57 0.015
aging GO:0007568 2 0.015
Worm
zymogen activation GO:0031638 3 0.015
angiogenesis GO:0001525 158 0.015
rna localization GO:0006403 4 0.015
regulation of cellular amine metabolic process GO:0033238 0 0.015
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.014
lymphocyte proliferation GO:0046651 1 0.014
transcription dna templated GO:0006351 181 0.014
macromolecule methylation GO:0043414 19 0.014
regulation of macromolecule biosynthetic process GO:0010556 225 0.014
positive regulation of transport GO:0051050 2 0.014
nucleobase containing compound transport GO:0015931 2 0.014
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.014
regulation of response to stimulus GO:0048583 269 0.014
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.014
regulation of chromosome segregation GO:0051983 1 0.013
regulation of protein complex assembly GO:0043254 3 0.013
cellular component disassembly GO:0022411 1 0.013
lateral inhibition GO:0046331 1 0.013
positive regulation of chromosome organization GO:2001252 1 0.013
meiotic spindle organization GO:0000212 1 0.013
head development GO:0060322 303 0.012
negative regulation of cellular biosynthetic process GO:0031327 55 0.012
muscle structure development GO:0061061 196 0.012
cell aging GO:0007569 2 0.012
cell part morphogenesis GO:0032990 246 0.012
small molecule metabolic process GO:0044281 77 0.012
central nervous system development GO:0007417 387 0.012
positive regulation of metabolic process GO:0009893 108 0.012
tissue regeneration GO:0042246 74 0.012
urogenital system development GO:0001655 97 0.012
organic acid metabolic process GO:0006082 31 0.012
regulation of mitotic cell cycle phase transition GO:1901990 8 0.012
telomere organization GO:0032200 1 0.012
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.012
cell fate commitment GO:0045165 99 0.012
transcription from rna polymerase ii promoter GO:0006366 80 0.011
death GO:0016265 121 0.011
regulation of chromatin modification GO:1903308 5 0.011
histone h3 k36 methylation GO:0010452 2 0.011
negative regulation of ras protein signal transduction GO:0046580 1 0.011
establishment of organelle localization GO:0051656 45 0.011
Worm
guanosine containing compound metabolic process GO:1901068 4 0.011
synapsis GO:0007129 1 0.011
cell death GO:0008219 121 0.011
response to chemical GO:0042221 320 0.011
response to alkaloid GO:0043279 2 0.011
negative regulation of rna metabolic process GO:0051253 48 0.011
positive regulation of cell activation GO:0050867 1 0.011
positive regulation of gene expression GO:0010628 71 0.011
mitotic cell cycle embryonic GO:0045448 2 0.011
hematopoietic stem cell migration GO:0035701 4 0.011
signal transduction GO:0007165 455 0.010
intrinsic apoptotic signaling pathway GO:0097193 20 0.010
vesicle mediated transport GO:0016192 22 0.010
deoxyribonucleotide biosynthetic process GO:0009263 1 0.010
peptidyl threonine modification GO:0018210 1 0.010
cellular response to oxygen containing compound GO:1901701 20 0.010

pola1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.013
nervous system disease DOID:863 0 0.013