Danio rerio

92 known processes

lmx1b.1

LIM homeobox transcription factor 1, beta 1

(Aliases: lmx1b)

lmx1b.1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
brain development GO:0007420 293 0.998
lateral line system development GO:0048925 76 0.998
sensory organ development GO:0007423 393 0.996
sensory system development GO:0048880 76 0.996
neural crest cell development GO:0014032 62 0.995
diencephalon development GO:0021536 58 0.994
Zebrafish
pronephric nephron development GO:0039019 14 0.994
eye development GO:0001654 277 0.988
pronephric glomerulus development GO:0039021 13 0.988
embryonic organ development GO:0048568 381 0.987
sensory organ morphogenesis GO:0090596 200 0.985
pronephros development GO:0048793 69 0.982
head development GO:0060322 303 0.979
camera type eye morphogenesis GO:0048593 108 0.979
nitrogen compound metabolic process GO:0006807 319 0.965
Human Mouse Worm
heterocycle biosynthetic process GO:0018130 215 0.962
Human Mouse
cellular nitrogen compound biosynthetic process GO:0044271 218 0.945
Human Mouse
response to external stimulus GO:0009605 264 0.943
Zebrafish
inner ear development GO:0048839 126 0.938
kidney development GO:0001822 92 0.935
embryonic camera type eye development GO:0031076 29 0.931
otic vesicle morphogenesis GO:0071600 34 0.931
eye morphogenesis GO:0048592 144 0.929
regulation of primary metabolic process GO:0080090 311 0.919
Human Mouse
morphogenesis of an epithelial sheet GO:0002011 49 0.916
inner ear receptor cell development GO:0060119 20 0.912
morphogenesis of an epithelium GO:0002009 333 0.909
regulation of metabolic process GO:0019222 359 0.907
Human Zebrafish Mouse Worm
regulation of gene expression GO:0010468 265 0.906
Human Zebrafish Mouse Worm
inner ear morphogenesis GO:0042472 63 0.900
ear development GO:0043583 127 0.900
heterocycle metabolic process GO:0046483 290 0.900
Human Mouse
inner ear receptor cell differentiation GO:0060113 29 0.896
otic vesicle development GO:0071599 42 0.896
regulation of biosynthetic process GO:0009889 250 0.894
Human Mouse
negative regulation of biological process GO:0048519 304 0.892
blood vessel morphogenesis GO:0048514 216 0.887
embryonic camera type eye morphogenesis GO:0048596 19 0.874
cellular aromatic compound metabolic process GO:0006725 295 0.874
Human Mouse
cell motility GO:0048870 244 0.867
Mouse
neuron development GO:0048666 262 0.857
nucleobase containing compound biosynthetic process GO:0034654 205 0.856
Human Mouse
generation of neurons GO:0048699 385 0.850
neuroblast differentiation GO:0014016 1 0.841
positive regulation of rna metabolic process GO:0051254 59 0.836
Mouse
ear morphogenesis GO:0042471 64 0.834
midbrain hindbrain boundary development GO:0030917 23 0.833
cell surface receptor signaling pathway GO:0007166 325 0.828
blood vessel development GO:0001568 246 0.826
mesoderm development GO:0007498 88 0.812
organic cyclic compound metabolic process GO:1901360 301 0.812
Human Mouse
lateral line development GO:0048882 66 0.811
tube morphogenesis GO:0035239 349 0.810
organic substance biosynthetic process GO:1901576 289 0.805
Human Mouse Worm
mechanosensory lateral line system development GO:0048881 49 0.795
stem cell development GO:0048864 82 0.793
positive regulation of macromolecule metabolic process GO:0010604 93 0.793
Mouse
tissue migration GO:0090130 37 0.790
regulation of biological quality GO:0065008 263 0.784
signal transduction GO:0007165 455 0.779
macromolecule biosynthetic process GO:0009059 227 0.774
Human Mouse
epithelial cell morphogenesis GO:0003382 2 0.764
closure of optic fissure GO:0061386 6 0.763
embryonic camera type eye formation GO:0060900 10 0.762
camera type eye development GO:0043010 222 0.759
epithelial tube morphogenesis GO:0060562 148 0.753
glomerulus morphogenesis GO:0072102 7 0.750
regulation of transcription dna templated GO:0006355 213 0.740
Human Mouse
cellular component biogenesis GO:0044085 178 0.739
regulation of cellular metabolic process GO:0031323 320 0.737
Human Mouse
regulation of multicellular organismal process GO:0051239 277 0.731
Zebrafish
nucleic acid templated transcription GO:0097659 181 0.729
Human Mouse
oligodendrocyte differentiation GO:0048709 23 0.726
aorta development GO:0035904 4 0.715
regulation of signal transduction GO:0009966 225 0.703
cellular nitrogen compound metabolic process GO:0034641 290 0.695
Human Mouse
angiogenesis GO:0001525 158 0.693
negative regulation of cellular process GO:0048523 283 0.691
dopaminergic neuron differentiation GO:0071542 14 0.686
Mouse
nucleobase containing compound metabolic process GO:0006139 274 0.682
Human Mouse
sympathetic nervous system development GO:0048485 3 0.674
otic placode formation GO:0043049 23 0.668
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.659
Mouse
auditory receptor cell differentiation GO:0042491 15 0.657
optic cup morphogenesis involved in camera type eye development GO:0002072 7 0.652
system process GO:0003008 185 0.651
Zebrafish Worm
cartilage development GO:0051216 96 0.638
embryonic organ morphogenesis GO:0048562 274 0.637
organelle organization GO:0006996 227 0.636
embryonic eye morphogenesis GO:0048048 30 0.630
positive regulation of metabolic process GO:0009893 108 0.623
Mouse
epithelium migration GO:0090132 25 0.615
forebrain neuron development GO:0021884 7 0.614
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.599
Human Mouse
single organism metabolic process GO:0044710 217 0.593
Worm
ameboidal type cell migration GO:0001667 143 0.586
aorta morphogenesis GO:0035909 3 0.581
regulation of signaling GO:0023051 235 0.578
urogenital system development GO:0001655 97 0.566
retina morphogenesis in camera type eye GO:0060042 79 0.565
negative regulation of cellular biosynthetic process GO:0031327 55 0.564
regulation of nitrogen compound metabolic process GO:0051171 251 0.560
Human Mouse
negative regulation of programmed cell death GO:0043069 58 0.546
rostrocaudal neural tube patterning GO:0021903 29 0.542
otic vesicle formation GO:0030916 27 0.542
inner ear receptor cell fate commitment GO:0060120 4 0.534
vasculature development GO:0001944 278 0.533
regulation of cell death GO:0010941 103 0.533
midbrain development GO:0030901 28 0.531
Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.526
Mouse
patterning of blood vessels GO:0001569 15 0.522
skin development GO:0043588 54 0.522
rna metabolic process GO:0016070 219 0.521
Human Mouse
otolith development GO:0048840 32 0.517
positive regulation of cellular metabolic process GO:0031325 94 0.514
Mouse
neural tube development GO:0021915 62 0.512
artery development GO:0060840 22 0.510
regulation of rna biosynthetic process GO:2001141 213 0.507
Human Mouse
positive regulation of gene expression GO:0010628 71 0.506
Mouse
regeneration GO:0031099 91 0.500
neuroblast fate commitment GO:0014017 1 0.500
oligodendrocyte development GO:0014003 7 0.497
biosynthetic process GO:0009058 294 0.496
Human Mouse Worm
glomerulus development GO:0032835 27 0.493
cellular biosynthetic process GO:0044249 286 0.490
Human Mouse Worm
tissue remodeling GO:0048771 4 0.487
forebrain neuron differentiation GO:0021879 14 0.482
gene expression GO:0010467 252 0.479
Human Zebrafish Mouse Worm
organic cyclic compound biosynthetic process GO:1901362 223 0.475
Human Mouse
lateral line nerve glial cell development GO:0048937 6 0.471
neuronal stem cell maintenance GO:0097150 2 0.462
ion transport GO:0006811 114 0.461
auditory receptor cell fate commitment GO:0009912 4 0.460
nose development GO:0043584 3 0.458
positive regulation of cellular process GO:0048522 201 0.456
Mouse
response to stress GO:0006950 263 0.456
cellular amine metabolic process GO:0044106 2 0.455
digestive tract development GO:0048565 265 0.452
central nervous system development GO:0007417 387 0.449
retina development in camera type eye GO:0060041 146 0.447
tissue homeostasis GO:0001894 25 0.441
programmed cell death GO:0012501 119 0.436
gland development GO:0048732 143 0.436
neural crest cell migration GO:0001755 42 0.435
photoreceptor cell differentiation GO:0046530 55 0.435
neural crest cell differentiation GO:0014033 72 0.434
mesenchyme development GO:0060485 127 0.433
central nervous system myelination GO:0022010 2 0.433
growth GO:0040007 174 0.424
Zebrafish Mouse
ventral spinal cord development GO:0021517 35 0.423
Zebrafish
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.421
Mouse
regulation of macromolecule metabolic process GO:0060255 317 0.417
Human Zebrafish Mouse Worm
regulation of nervous system development GO:0051960 90 0.417
positive regulation of cell cycle GO:0045787 3 0.412
hair cell differentiation GO:0035315 32 0.407
negative regulation of cellular metabolic process GO:0031324 77 0.403
vestibular receptor cell differentiation GO:0060114 3 0.401
regulation of localization GO:0032879 104 0.400
lateral inhibition GO:0046331 1 0.400
regulation of peptidase activity GO:0052547 23 0.398
mesoderm morphogenesis GO:0048332 51 0.396
cation transmembrane transport GO:0098655 65 0.392
cellular component morphogenesis GO:0032989 336 0.391
Zebrafish Worm Fly
negative regulation of cellular component movement GO:0051271 18 0.385
glandular epithelial cell differentiation GO:0002067 9 0.382
Zebrafish
anterior posterior pattern specification GO:0009952 152 0.382
negative regulation of locomotion GO:0040013 18 0.381
leukocyte differentiation GO:0002521 25 0.377
behavior GO:0007610 74 0.373
Zebrafish Worm
positive regulation of biosynthetic process GO:0009891 68 0.369
Mouse
glial cell development GO:0021782 20 0.368
cellular component assembly involved in morphogenesis GO:0010927 107 0.364
regulation of cellular biosynthetic process GO:0031326 245 0.363
Human Mouse
actin filament based process GO:0030029 64 0.362
regulation of stem cell differentiation GO:2000736 4 0.352
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.344
Mouse
branching morphogenesis of an epithelial tube GO:0048754 15 0.342
regulation of macromolecule biosynthetic process GO:0010556 225 0.339
Human Mouse
gliogenesis GO:0042063 45 0.338
regulation of developmental process GO:0050793 247 0.337
heart morphogenesis GO:0003007 156 0.337
stem cell division GO:0017145 1 0.336
morphogenesis of embryonic epithelium GO:0016331 30 0.336
lymphangiogenesis GO:0001946 25 0.334
regulation of multicellular organismal development GO:2000026 223 0.330
axial mesoderm morphogenesis GO:0048319 8 0.330
negative regulation of multicellular organismal process GO:0051241 69 0.330
semicircular canal morphogenesis GO:0048752 18 0.327
neuron projection morphogenesis GO:0048812 161 0.326
Zebrafish Worm Fly
cell migration GO:0016477 237 0.325
Mouse
locomotion GO:0040011 313 0.325
Zebrafish Mouse
cellular macromolecule biosynthetic process GO:0034645 224 0.325
Human Mouse
epithelial cell development GO:0002064 42 0.325
response to wounding GO:0009611 116 0.323
regulation of retina development in camera type eye GO:1902866 2 0.322
stem cell maintenance GO:0019827 4 0.320
stem cell fate commitment GO:0048865 1 0.316
immune system development GO:0002520 191 0.315
regulation of organ growth GO:0046620 3 0.313
apoptotic process GO:0006915 116 0.312
cell morphogenesis GO:0000902 289 0.310
Zebrafish Worm Fly
cation transport GO:0006812 81 0.298
ectoderm development GO:0007398 9 0.297
central nervous system neuron differentiation GO:0021953 74 0.297
Zebrafish Mouse
negative regulation of apoptotic process GO:0043066 55 0.297
regulation of organelle organization GO:0033043 29 0.296
aromatic compound biosynthetic process GO:0019438 217 0.295
Human Mouse
response to hydrogen peroxide GO:0042542 3 0.295
cellular response to endogenous stimulus GO:0071495 68 0.293
homeostatic process GO:0042592 142 0.293
death GO:0016265 121 0.289
mesenchymal cell differentiation GO:0048762 87 0.289
neuromast development GO:0048884 46 0.289
organonitrogen compound metabolic process GO:1901564 74 0.287
Worm
thyroid gland development GO:0030878 12 0.285
epidermis development GO:0008544 48 0.272
positive regulation of epithelial cell differentiation GO:0030858 2 0.271
somitogenesis GO:0001756 87 0.271
habenula development GO:0021986 9 0.268
neurological system process GO:0050877 62 0.267
mechanoreceptor differentiation GO:0042490 37 0.267
enteric nervous system development GO:0048484 12 0.267
negative regulation of developmental process GO:0051093 65 0.267
amine metabolic process GO:0009308 2 0.265
positive regulation of neural precursor cell proliferation GO:2000179 1 0.264
negative regulation of macromolecule metabolic process GO:0010605 76 0.262
regulation of hydrolase activity GO:0051336 28 0.260
ectodermal placode formation GO:0060788 26 0.260
localization of cell GO:0051674 244 0.259
Mouse
single organism localization GO:1902578 225 0.255
Fly
epidermal cell differentiation GO:0009913 36 0.254
chordate embryonic development GO:0043009 271 0.253
auditory receptor cell development GO:0060117 8 0.252
hemopoiesis GO:0030097 183 0.252
posterior lateral line system development GO:0048915 46 0.251
cell differentiation in hindbrain GO:0021533 5 0.251
single organism organelle organization GO:1902589 199 0.250
apoptotic process involved in development GO:1902742 2 0.249
artery morphogenesis GO:0048844 14 0.248
cell cycle GO:0007049 93 0.246
response to chemical GO:0042221 320 0.246
Zebrafish
developmental growth GO:0048589 166 0.245
Zebrafish
nerve development GO:0021675 45 0.243
Zebrafish
endoderm development GO:0007492 49 0.242
pancreatic d cell differentiation GO:0003311 2 0.240
Zebrafish
hematopoietic or lymphoid organ development GO:0048534 191 0.240
epithelial cell differentiation GO:0030855 116 0.239
cranial ganglion development GO:0061550 3 0.239
somatic stem cell maintenance GO:0035019 1 0.232
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.229
rna biosynthetic process GO:0032774 181 0.228
Human Mouse
response to inorganic substance GO:0010035 38 0.227
regulation of cell communication GO:0010646 232 0.225
fourth ventricle development GO:0021592 8 0.223
endochondral bone morphogenesis GO:0060350 8 0.220
neuron fate commitment GO:0048663 26 0.218
Zebrafish
positive regulation of nucleic acid templated transcription GO:1903508 57 0.215
Mouse
apoptotic process involved in morphogenesis GO:0060561 2 0.212
larval development GO:0002164 2 0.211
autonomic nervous system development GO:0048483 19 0.211
nephron development GO:0072006 31 0.211
regulation of rna metabolic process GO:0051252 224 0.210
Human Mouse
regulation of cell cycle GO:0051726 52 0.207
cardiac cell fate commitment GO:0060911 1 0.207
cell death GO:0008219 121 0.205
neuron differentiation GO:0030182 353 0.202
lateral line nerve development GO:0048892 9 0.200
metal ion transport GO:0030001 58 0.200
cellular protein modification process GO:0006464 100 0.196
neuronal action potential GO:0019228 18 0.195
cell differentiation in spinal cord GO:0021515 40 0.193
Zebrafish
multicellular organismal reproductive process GO:0048609 35 0.192
cerebellum formation GO:0021588 2 0.191
ventricular system development GO:0021591 12 0.182
regulation of apoptotic process GO:0042981 98 0.181
regulation of photoreceptor cell differentiation GO:0046532 2 0.181
regulation of vesicle mediated transport GO:0060627 9 0.181
otolith morphogenesis GO:0032474 8 0.181
pigmentation GO:0043473 85 0.180
glial cell differentiation GO:0010001 42 0.178
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.177
negative regulation of stem cell differentiation GO:2000737 2 0.177
hindbrain development GO:0030902 91 0.177
polarized epithelial cell differentiation GO:0030859 4 0.176
cell projection organization GO:0030030 284 0.173
Zebrafish Worm Fly
hypochord development GO:0055016 3 0.173
lymph vessel development GO:0001945 27 0.173
tissue regeneration GO:0042246 74 0.171
positive regulation of nervous system development GO:0051962 25 0.171
developmental programmed cell death GO:0010623 4 0.171
cellular response to stress GO:0033554 62 0.170
regulation of mechanoreceptor differentiation GO:0045631 1 0.168
apoptotic signaling pathway GO:0097190 23 0.168
stem cell differentiation GO:0048863 117 0.167
sequestering of metal ion GO:0051238 3 0.166
type b pancreatic cell development GO:0003323 4 0.162
Zebrafish
gastrulation GO:0007369 208 0.162
macromolecular complex subunit organization GO:0043933 74 0.162
Mouse
glial cell fate commitment GO:0021781 6 0.161
peripheral nervous system neuron differentiation GO:0048934 28 0.160
Zebrafish
regulation of catalytic activity GO:0050790 55 0.159
regulation of behavior GO:0050795 24 0.156
reproductive process GO:0022414 40 0.155
Worm
axial mesoderm development GO:0048318 10 0.155
inner ear receptor stereocilium organization GO:0060122 8 0.155
distal tubule development GO:0072017 1 0.154
venous blood vessel development GO:0060841 9 0.152
regulation of response to stimulus GO:0048583 269 0.151
positive regulation of mesodermal cell fate specification GO:0048337 1 0.151
cell fate commitment GO:0045165 99 0.150
Zebrafish
stem cell fate determination GO:0048867 1 0.149
fin morphogenesis GO:0033334 53 0.149
response to amine GO:0014075 1 0.148
positive regulation of gastrulation GO:2000543 2 0.147
post embryonic organ development GO:0048569 4 0.147
neuroblast proliferation GO:0007405 2 0.147
positive regulation of cell differentiation GO:0045597 30 0.145
catecholamine metabolic process GO:0006584 2 0.145
ectodermal placode morphogenesis GO:0071697 32 0.143
neural plate pattern specification GO:0060896 12 0.143
endothelial cell differentiation GO:0045446 20 0.143
nucleic acid metabolic process GO:0090304 244 0.141
Human Mouse
auditory receptor cell fate determination GO:0042668 2 0.141
water homeostasis GO:0030104 4 0.139
organelle assembly GO:0070925 110 0.139
cell cell signaling involved in cell fate commitment GO:0045168 12 0.139
regulation of cell development GO:0060284 100 0.136
hypothalamus cell differentiation GO:0021979 4 0.134
negative regulation of nucleic acid templated transcription GO:1903507 45 0.134
regulation of programmed cell death GO:0043067 101 0.132
radial glial cell differentiation GO:0060019 2 0.131
aging GO:0007568 2 0.131
ventral midline development GO:0007418 13 0.131
regulation of cellular amine metabolic process GO:0033238 0 0.129
regulation of cysteine type endopeptidase activity GO:2000116 21 0.129
regionalization GO:0003002 274 0.128
negative regulation of rna biosynthetic process GO:1902679 45 0.128
cellular macromolecule metabolic process GO:0044260 391 0.128
Human Mouse
regulation of circadian rhythm GO:0042752 4 0.125
enzyme linked receptor protein signaling pathway GO:0007167 106 0.125
embryo development ending in birth or egg hatching GO:0009792 271 0.124
negative regulation of metabolic process GO:0009892 86 0.123
lymph vessel morphogenesis GO:0036303 25 0.122
pronephric glomerulus morphogenesis GO:0035775 6 0.122
response to organic substance GO:0010033 153 0.122
positive regulation of biological process GO:0048518 253 0.122
Mouse
neuron projection guidance GO:0097485 86 0.120
Zebrafish
positive regulation of notch signaling pathway GO:0045747 3 0.119
negative regulation of biosynthetic process GO:0009890 55 0.118
negative regulation of cell communication GO:0010648 96 0.116
lateral line nerve glial cell morphogenesis involved in differentiation GO:0048938 5 0.116
axon ensheathment GO:0008366 18 0.115
embryonic skeletal system morphogenesis GO:0048704 93 0.114
hindbrain formation GO:0021576 3 0.114
negative regulation of cell migration GO:0030336 17 0.114
negative regulation of cell death GO:0060548 60 0.114
mesenchymal cell development GO:0014031 78 0.114
regulation of axonogenesis GO:0050770 32 0.113
transmission of nerve impulse GO:0019226 19 0.113
regulation of axon guidance GO:1902667 8 0.112
intracellular signal transduction GO:0035556 85 0.111
rhombomere development GO:0021546 19 0.111
negative regulation of cysteine type endopeptidase activity GO:2000117 8 0.110
regulation of vascular permeability GO:0043114 5 0.110
neuromast deposition GO:0048885 9 0.110
regulation of canonical wnt signaling pathway GO:0060828 34 0.109
phenol containing compound biosynthetic process GO:0046189 4 0.109
negative regulation of chemotaxis GO:0050922 4 0.109
cell part morphogenesis GO:0032990 246 0.107
Zebrafish Worm Fly
connective tissue development GO:0061448 99 0.107
multi organism reproductive process GO:0044703 36 0.107
bone remodeling GO:0046849 2 0.106
endocardium formation GO:0060214 1 0.105
chemical homeostasis GO:0048878 49 0.105
cellular response to external stimulus GO:0071496 2 0.104
multicellular organismal homeostasis GO:0048871 29 0.104
epithelial cell migration GO:0010631 25 0.103
regulation of cell differentiation GO:0045595 142 0.102
forebrain generation of neurons GO:0021872 14 0.102
cardiac ventricle morphogenesis GO:0003208 7 0.102
regulation of notch signaling pathway GO:0008593 16 0.101
formation of anatomical boundary GO:0048859 14 0.100
neuroblast fate determination GO:0007400 1 0.099
glial cell migration GO:0008347 3 0.098
transcription dna templated GO:0006351 181 0.098
Human Mouse
negative regulation of catalytic activity GO:0043086 21 0.098
cellular ketone metabolic process GO:0042180 11 0.096
axonogenesis GO:0007409 152 0.095
Zebrafish Worm
hepatocyte proliferation GO:0072574 2 0.095
fin regeneration GO:0031101 51 0.095
axon ensheathment in central nervous system GO:0032291 2 0.095
positive regulation of transcription dna templated GO:0045893 57 0.095
Mouse
photoreceptor cell fate commitment GO:0046552 1 0.094
regulation of phosphorus metabolic process GO:0051174 43 0.094
embryonic heart tube development GO:0035050 133 0.094
reflex GO:0060004 2 0.094
pancreatic a cell development GO:0003322 2 0.093
Zebrafish
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.092
appendage morphogenesis GO:0035107 56 0.092
Mouse
cardiocyte differentiation GO:0035051 44 0.091
Zebrafish
positive regulation of cell communication GO:0010647 56 0.091
fin development GO:0033333 77 0.090
renal system development GO:0072001 94 0.090
catechol containing compound biosynthetic process GO:0009713 2 0.090
regulation of inner ear receptor cell differentiation GO:2000980 1 0.089
nephron tubule morphogenesis GO:0072078 1 0.089
regulation of cell migration GO:0030334 40 0.089
embryonic limb morphogenesis GO:0030326 2 0.089
exocrine pancreas development GO:0031017 28 0.089
Zebrafish
establishment of endothelial barrier GO:0061028 3 0.088
outflow tract morphogenesis GO:0003151 1 0.088
regulation of neural retina development GO:0061074 2 0.088
morphogenesis of a branching epithelium GO:0061138 16 0.087
phosphorus metabolic process GO:0006793 109 0.087
epithalamus development GO:0021538 10 0.087
ventral spinal cord interneuron differentiation GO:0021514 12 0.086
regulation of kinase activity GO:0043549 15 0.086
taxis GO:0042330 109 0.086
Zebrafish
neuron fate determination GO:0048664 2 0.086
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.086
Human Mouse
cerebellar granular layer formation GO:0021684 3 0.085
appendage development GO:0048736 80 0.085
Mouse
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.085
regulation of mesodermal cell fate specification GO:0042661 9 0.085
venous endothelial cell migration involved in lymph vessel development GO:0060855 4 0.084
small molecule metabolic process GO:0044281 77 0.084
Worm
catecholamine biosynthetic process GO:0042423 2 0.084
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 7 0.083
cranial nerve development GO:0021545 42 0.083
Zebrafish
vestibular receptor cell development GO:0060118 3 0.082
forebrain development GO:0030900 96 0.082
Zebrafish
regulation of molecular function GO:0065009 70 0.081
eye photoreceptor cell differentiation GO:0001754 45 0.081
positive regulation of rna biosynthetic process GO:1902680 57 0.081
Mouse
regulation of reproductive process GO:2000241 4 0.080
negative regulation of epithelial cell migration GO:0010633 1 0.080
regulation of cellular amino acid metabolic process GO:0006521 0 0.080
embryonic skeletal joint development GO:0072498 3 0.080
cilium morphogenesis GO:0060271 85 0.079
glial cell fate determination GO:0007403 1 0.079
positive regulation of cellular component biogenesis GO:0044089 3 0.079
hepaticobiliary system development GO:0061008 98 0.078
wound healing GO:0042060 90 0.078
notch signaling pathway GO:0007219 35 0.078
female gamete generation GO:0007292 14 0.077
anterior commissure morphogenesis GO:0021960 3 0.077
axon guidance GO:0007411 86 0.077
Zebrafish
cellular component movement GO:0006928 335 0.077
Zebrafish Mouse
hindbrain morphogenesis GO:0021575 22 0.077
Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.076
embryonic heart tube formation GO:0003144 1 0.076
protein modification process GO:0036211 100 0.075
gamete generation GO:0007276 33 0.075
cellular protein metabolic process GO:0044267 129 0.074
axon development GO:0061564 166 0.074
Zebrafish Worm
neural tube patterning GO:0021532 33 0.074
regulation of neurogenesis GO:0050767 87 0.074
protein metabolic process GO:0019538 183 0.074
exocrine system development GO:0035272 28 0.074
Zebrafish
regulation of anatomical structure morphogenesis GO:0022603 130 0.074
cellular response to organic substance GO:0071310 105 0.073
gland morphogenesis GO:0022612 13 0.073
positive regulation of neurogenesis GO:0050769 24 0.073
vascular process in circulatory system GO:0003018 6 0.072
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.072
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.072
cilium organization GO:0044782 71 0.071
glial cell proliferation GO:0014009 4 0.071
phagocytosis GO:0006909 3 0.071
Fly
left right pattern formation GO:0060972 19 0.070
vestibular reflex GO:0060005 2 0.070
phosphorylation GO:0016310 69 0.070
regulation of protein localization to nucleus GO:1900180 2 0.070
regulation of neuron differentiation GO:0045664 56 0.070
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.070
erk1 and erk2 cascade GO:0070371 4 0.069
cell morphogenesis involved in differentiation GO:0000904 195 0.069
Zebrafish Worm Fly
regulation of locomotion GO:0040012 55 0.069
neuron migration GO:0001764 22 0.069
Mouse
cell proliferation in forebrain GO:0021846 3 0.068
ganglion development GO:0061548 5 0.068
actin cytoskeleton organization GO:0030036 63 0.067
regulation of membrane potential GO:0042391 23 0.067
neuron fate specification GO:0048665 20 0.067
Zebrafish
ensheathment of neurons GO:0007272 18 0.067
negative regulation of cell motility GO:2000146 17 0.066
central nervous system neuron axonogenesis GO:0021955 18 0.065
regulation of tube size GO:0035150 2 0.065
transcription from rna polymerase ii promoter GO:0006366 80 0.064
Mouse
embryonic skeletal system development GO:0048706 97 0.064
vasculogenesis GO:0001570 41 0.064
regulation of stem cell proliferation GO:0072091 2 0.064
stem cell proliferation GO:0072089 4 0.063
cartilage development involved in endochondral bone morphogenesis GO:0060351 8 0.063
dorsal ventral pattern formation GO:0009953 125 0.063
Mouse
respiratory system development GO:0060541 5 0.063
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.063
negative regulation of gene expression GO:0010629 65 0.063

lmx1b.1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.233