Danio rerio

0 known processes

psmb5

proteasome (prosome, macropain) subunit, beta type, 5

(Aliases: etID309919.2,fb59c07,wu:fb59c07,x,zgc:86820,si:zc14a17.13)

psmb5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ubiquitin dependent protein catabolic process GO:0006511 3 0.676
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.656
modification dependent protein catabolic process GO:0019941 3 0.550
larval development GO:0002164 2 0.496
proteasomal protein catabolic process GO:0010498 2 0.476
cellular protein catabolic process GO:0044257 4 0.443
aging GO:0007568 2 0.415
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.332
modification dependent macromolecule catabolic process GO:0043632 3 0.254
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.207
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.128
single fertilization GO:0007338 3 0.118
regulation of developmental process GO:0050793 247 0.118
cellular macromolecule metabolic process GO:0044260 391 0.108
cellular macromolecule catabolic process GO:0044265 12 0.104
cytokinesis GO:0000910 3 0.099
single organism organelle organization GO:1902589 199 0.087
rrna catabolic process GO:0016075 1 0.080
dna templated transcription initiation GO:0006352 1 0.076
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.069
regulation of protein complex assembly GO:0043254 3 0.068
regulation of macromolecule metabolic process GO:0060255 317 0.066
embryo development ending in birth or egg hatching GO:0009792 271 0.065
protein metabolic process GO:0019538 183 0.063
regulation of nitrogen compound metabolic process GO:0051171 251 0.063
regulation of cellular protein catabolic process GO:1903362 1 0.061
organic cyclic compound metabolic process GO:1901360 301 0.059
organic substance catabolic process GO:1901575 28 0.057
rna metabolic process GO:0016070 219 0.056
regulation of protein catabolic process GO:0042176 1 0.055
catabolic process GO:0009056 32 0.055
regulation of cellular metabolic process GO:0031323 320 0.054
cellular nitrogen compound biosynthetic process GO:0044271 218 0.053
regulation of primary metabolic process GO:0080090 311 0.053
proteolysis GO:0006508 38 0.053
regulation of transcription dna templated GO:0006355 213 0.051
heterocycle metabolic process GO:0046483 290 0.051
regulation of peptidase activity GO:0052547 23 0.049
transport GO:0006810 220 0.048
cellular nitrogen compound metabolic process GO:0034641 290 0.048
autophagy GO:0006914 4 0.047
locomotion GO:0040011 313 0.046
organelle organization GO:0006996 227 0.046
response to stress GO:0006950 263 0.046
cell cycle process GO:0022402 53 0.045
regulation of dna templated transcription elongation GO:0032784 3 0.044
organelle assembly GO:0070925 110 0.044
nitrogen compound metabolic process GO:0006807 319 0.043
nucleoside monophosphate catabolic process GO:0009125 4 0.043
positive regulation of cellular component biogenesis GO:0044089 3 0.042
ncrna catabolic process GO:0034661 1 0.042
dna templated transcription elongation GO:0006354 3 0.042
protein secretion GO:0009306 1 0.041
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.041
mitotic cell cycle process GO:1903047 48 0.039
regulation of cell differentiation GO:0045595 142 0.038
positive regulation of cellular process GO:0048522 201 0.038
cellular component assembly GO:0022607 170 0.038
multicellular organism growth GO:0035264 4 0.037
development of primary female sexual characteristics GO:0046545 4 0.037
regulation of rna biosynthetic process GO:2001141 213 0.037
maintenance of location GO:0051235 4 0.036
macroautophagy GO:0016236 1 0.035
cellular aromatic compound metabolic process GO:0006725 295 0.035
atp catabolic process GO:0006200 4 0.035
nucleobase containing compound biosynthetic process GO:0034654 205 0.035
nucleobase containing compound metabolic process GO:0006139 274 0.034
regulation of gene expression GO:0010468 265 0.034
regulation of multicellular organismal process GO:0051239 277 0.033
establishment of localization GO:0051234 244 0.032
pole plasm assembly GO:0007315 4 0.031
nucleic acid metabolic process GO:0090304 244 0.031
regulation of mrna processing GO:0050684 3 0.031
cellular biosynthetic process GO:0044249 286 0.031
cell motility GO:0048870 244 0.031
positive regulation of protein complex assembly GO:0031334 2 0.031
meiotic chromosome segregation GO:0045132 3 0.030
fertilization GO:0009566 3 0.030
meiotic cell cycle process GO:1903046 3 0.030
positive regulation of dna templated transcription elongation GO:0032786 1 0.030
ribonucleoside monophosphate catabolic process GO:0009158 4 0.029
regulation of proteolysis GO:0030162 24 0.029
double strand break repair via homologous recombination GO:0000724 1 0.029
protein acetylation GO:0006473 2 0.028
positive regulation of cell cycle GO:0045787 3 0.028
heterocycle biosynthetic process GO:0018130 215 0.027
nucleic acid templated transcription GO:0097659 181 0.027
organic substance transport GO:0071702 58 0.027
organic cyclic compound biosynthetic process GO:1901362 223 0.027
regulation of rna metabolic process GO:0051252 224 0.026
lipid storage GO:0019915 1 0.026
nuclear migration GO:0007097 3 0.026
zymogen activation GO:0031638 3 0.026
establishment of protein localization to organelle GO:0072594 4 0.026
single organism transport GO:0044765 206 0.025
cellular macromolecule biosynthetic process GO:0034645 224 0.025
cellular protein modification process GO:0006464 100 0.025
regulation of protein ubiquitination GO:0031396 3 0.025
growth GO:0040007 174 0.024
adult behavior GO:0030534 2 0.024
mononuclear cell proliferation GO:0032943 1 0.024
cellular component disassembly GO:0022411 1 0.024
protein modification process GO:0036211 100 0.024
pronuclear migration GO:0035046 1 0.024
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.024
rna biosynthetic process GO:0032774 181 0.023
chromosome organization GO:0051276 31 0.023
regulation of biological quality GO:0065008 263 0.023
regulation of establishment of protein localization GO:0070201 4 0.023
positive regulation of metabolic process GO:0009893 108 0.023
biosynthetic process GO:0009058 294 0.022
negative regulation of cellular process GO:0048523 283 0.022
meiotic nuclear division GO:0007126 4 0.022
cellular component movement GO:0006928 335 0.022
regulation of endopeptidase activity GO:0052548 23 0.022
regulation of response to stimulus GO:0048583 269 0.022
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.022
stem cell proliferation GO:0072089 4 0.022
gene expression GO:0010467 252 0.021
regulation of binding GO:0051098 3 0.021
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.020
nucleocytoplasmic transport GO:0006913 4 0.020
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.020
positive regulation of cellular catabolic process GO:0031331 3 0.020
regulation of mrna splicing via spliceosome GO:0048024 3 0.020
single organism localization GO:1902578 225 0.020
maturation of ssu rrna GO:0030490 1 0.019
mitotic nuclear division GO:0007067 18 0.019
nuclear export GO:0051168 1 0.019
cellular protein metabolic process GO:0044267 129 0.019
protein localization to nucleus GO:0034504 3 0.019
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.019
macromolecule modification GO:0043412 111 0.019
internal peptidyl lysine acetylation GO:0018393 2 0.019
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.019
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.019
regulation of chromosome segregation GO:0051983 1 0.019
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 10 0.018
internal protein amino acid acetylation GO:0006475 2 0.018
myeloid cell differentiation GO:0030099 86 0.018
cellular catabolic process GO:0044248 27 0.018
regulation of metabolic process GO:0019222 359 0.018
immune system process GO:0002376 241 0.018
regulation of cell activation GO:0050865 1 0.018
transcription dna templated GO:0006351 181 0.018
dna biosynthetic process GO:0071897 3 0.018
positive regulation of macromolecule metabolic process GO:0010604 93 0.017
peptidyl lysine acetylation GO:0018394 2 0.017
negative regulation of cytoplasmic transport GO:1903650 2 0.017
cellular response to stress GO:0033554 62 0.017
single organism metabolic process GO:0044710 217 0.017
oocyte anterior posterior axis specification GO:0007314 4 0.017
cellular response to nutrient levels GO:0031669 2 0.017
female gonad development GO:0008585 4 0.017
programmed cell death GO:0012501 119 0.017
organelle localization GO:0051640 49 0.017
microtubule based process GO:0007017 60 0.017
centrosome organization GO:0051297 1 0.017
organic acid metabolic process GO:0006082 31 0.017
nephron tubule morphogenesis GO:0072078 1 0.016
neuroblast proliferation GO:0007405 2 0.016
macromolecular complex disassembly GO:0032984 1 0.016
transcription from rna polymerase ii promoter GO:0006366 80 0.016
regulation of inflammatory response GO:0050727 2 0.016
spindle assembly GO:0051225 2 0.016
regulation of stem cell proliferation GO:0072091 2 0.016
negative regulation of biological process GO:0048519 304 0.016
cellular component biogenesis GO:0044085 178 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.016
regulation of multicellular organismal development GO:2000026 223 0.016
cellular response to dna damage stimulus GO:0006974 24 0.016
establishment of localization in cell GO:0051649 77 0.016
mitochondrial transport GO:0006839 2 0.016
cell cycle GO:0007049 93 0.015
mitochondrion organization GO:0007005 4 0.015
sensory perception of chemical stimulus GO:0007606 3 0.015
positive regulation of chromosome organization GO:2001252 1 0.015
double strand break repair GO:0006302 3 0.015
organic substance biosynthetic process GO:1901576 289 0.015
nuclear import GO:0051170 3 0.015
positive regulation of catabolic process GO:0009896 4 0.015
oxoacid metabolic process GO:0043436 31 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.015
nuclear transport GO:0051169 4 0.015
apoptotic process GO:0006915 116 0.015
cellular response to extracellular stimulus GO:0031668 2 0.015
cell migration GO:0016477 237 0.015
regulation of apoptotic process GO:0042981 98 0.014
spermatid development GO:0007286 2 0.014
regulation of immune system process GO:0002682 34 0.014
protein modification by small protein conjugation or removal GO:0070647 14 0.014
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.014
protein import GO:0017038 3 0.014
cell projection morphogenesis GO:0048858 244 0.014
negative regulation of protein transport GO:0051224 3 0.014
regulation of protein binding GO:0043393 3 0.014
cellular response to external stimulus GO:0071496 2 0.014
negative regulation of endopeptidase activity GO:0010951 10 0.014
protein homooligomerization GO:0051260 3 0.014
spindle assembly involved in mitosis GO:0090307 1 0.014
developmental growth GO:0048589 166 0.014
cellular response to starvation GO:0009267 1 0.014
protein complex disassembly GO:0043241 1 0.014
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.014
protein complex assembly GO:0006461 30 0.014
mitotic cell cycle GO:0000278 64 0.014
response to abiotic stimulus GO:0009628 122 0.013
positive regulation of chromatin modification GO:1903310 1 0.013
female sex differentiation GO:0046660 4 0.013
protein catabolic process GO:0030163 7 0.013
spliceosomal snrnp assembly GO:0000387 2 0.013
macromolecule biosynthetic process GO:0009059 227 0.013
regulation of cell maturation GO:1903429 1 0.013
regulation of multicellular organism growth GO:0040014 4 0.013
negative regulation of synapse assembly GO:0051964 2 0.013
regulation of programmed cell death GO:0043067 101 0.013
regulation of reproductive process GO:2000241 4 0.013
head development GO:0060322 303 0.013
male meiosis GO:0007140 2 0.012
recombinational repair GO:0000725 1 0.012
protein import into nucleus GO:0006606 3 0.012
macromolecule catabolic process GO:0009057 15 0.012
neuromuscular synaptic transmission GO:0007274 2 0.012
carboxylic acid metabolic process GO:0019752 22 0.012
single organism biosynthetic process GO:0044711 71 0.012
protein localization GO:0008104 40 0.012
protein maturation GO:0051604 12 0.012
protein targeting to nucleus GO:0044744 3 0.012
single organism nuclear import GO:1902593 3 0.012
cell cycle g1 s phase transition GO:0044843 1 0.012
cell proliferation GO:0008283 80 0.012
taxis GO:0042330 109 0.012
negative regulation of myeloid cell differentiation GO:0045638 1 0.012
regulation of synapse assembly GO:0051963 3 0.012
organonitrogen compound metabolic process GO:1901564 74 0.012
reproduction GO:0000003 40 0.012
negative regulation of intracellular transport GO:0032387 3 0.012
i kappab kinase nf kappab signaling GO:0007249 4 0.012
macromolecular complex subunit organization GO:0043933 74 0.012
cellular localization GO:0051641 97 0.012
cell substrate junction assembly GO:0007044 2 0.011
response to external stimulus GO:0009605 264 0.011
alternative mrna splicing via spliceosome GO:0000380 1 0.011
negative regulation of mitosis GO:0045839 3 0.011
actin cytoskeleton organization GO:0030036 63 0.011
small molecule metabolic process GO:0044281 77 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.011
nuclear division GO:0000280 23 0.011
negative regulation of cellular metabolic process GO:0031324 77 0.011
positive regulation of dna metabolic process GO:0051054 1 0.011
positive regulation of biological process GO:0048518 253 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.011
protein acylation GO:0043543 3 0.011
extrinsic apoptotic signaling pathway GO:0097191 3 0.011
cellular response to organic substance GO:0071310 105 0.011
macromolecule localization GO:0033036 54 0.011
chromatin organization GO:0006325 22 0.011
hemopoiesis GO:0030097 183 0.011
regulation of protein transport GO:0051223 3 0.011
cellular response to chemical stimulus GO:0070887 157 0.011
positive regulation of cytoskeleton organization GO:0051495 3 0.010
response to cadmium ion GO:0046686 14 0.010
synaptic growth at neuromuscular junction GO:0051124 2 0.010
regulation of dna recombination GO:0000018 2 0.010
astrocyte differentiation GO:0048708 1 0.010
signal transduction GO:0007165 455 0.010
positive regulation of developmental process GO:0051094 50 0.010
cellular response to molecule of bacterial origin GO:0071219 3 0.010
g1 s transition of mitotic cell cycle GO:0000082 1 0.010
cell cell recognition GO:0009988 1 0.010

psmb5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.045
nervous system disease DOID:863 0 0.026
motor neuron disease DOID:231 0 0.022
central nervous system disease DOID:331 0 0.022
amyotrophic lateral sclerosis DOID:332 0 0.022
neurodegenerative disease DOID:1289 0 0.022