Danio rerio

39 known processes

nkx2.2b

NK2 transcription factor related 2b

(Aliases: MGC113384)

nkx2.2b biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
ventral spinal cord interneuron differentiation GO:0021514 12 0.916
ventral midline development GO:0007418 13 0.859
positive regulation of cellular process GO:0048522 201 0.801
Worm
floor plate development GO:0033504 15 0.762
nitrogen compound metabolic process GO:0006807 319 0.729
Worm
oligodendrocyte cell fate specification GO:0021778 4 0.725
Zebrafish
regulation of metabolic process GO:0019222 359 0.719
Worm
spinal cord oligodendrocyte cell fate specification GO:0021530 2 0.719
Zebrafish
neuron fate commitment GO:0048663 26 0.716
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.692
Worm
ventral spinal cord development GO:0021517 35 0.657
rna biosynthetic process GO:0032774 181 0.649
Worm
cellular macromolecule biosynthetic process GO:0034645 224 0.631
Worm
regulation of rna biosynthetic process GO:2001141 213 0.629
Worm
regulation of transcription dna templated GO:0006355 213 0.589
Worm
nucleic acid templated transcription GO:0097659 181 0.588
Worm
regulation of gene expression GO:0010468 265 0.581
Worm
regulation of anatomical structure morphogenesis GO:0022603 130 0.554
Zebrafish
aromatic compound biosynthetic process GO:0019438 217 0.547
Worm
regulation of macromolecule metabolic process GO:0060255 317 0.541
Worm
nucleobase containing compound metabolic process GO:0006139 274 0.526
Worm
heterocycle biosynthetic process GO:0018130 215 0.515
Worm
neuron projection development GO:0031175 180 0.514
Zebrafish
cell differentiation in spinal cord GO:0021515 40 0.511
nucleobase containing compound biosynthetic process GO:0034654 205 0.510
Worm
regulation of cellular metabolic process GO:0031323 320 0.509
Worm
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.506
Worm
regulation of multicellular organismal development GO:2000026 223 0.503
Zebrafish
regulation of nucleic acid templated transcription GO:1903506 213 0.489
Worm
nucleic acid metabolic process GO:0090304 244 0.482
Worm
regulation of cellular biosynthetic process GO:0031326 245 0.482
Worm
spinal cord development GO:0021510 46 0.478
regulation of multicellular organismal process GO:0051239 277 0.458
Zebrafish
positive regulation of biological process GO:0048518 253 0.457
Worm
muscle cell differentiation GO:0042692 139 0.445
Zebrafish
cellular biosynthetic process GO:0044249 286 0.439
Worm
regulation of cardiac chamber morphogenesis GO:1901219 2 0.436
Zebrafish
cellular nitrogen compound metabolic process GO:0034641 290 0.422
Worm
organic cyclic compound biosynthetic process GO:1901362 223 0.422
Worm
oligodendrocyte differentiation GO:0048709 23 0.422
Zebrafish
cellular aromatic compound metabolic process GO:0006725 295 0.420
Worm
regulation of cell differentiation GO:0045595 142 0.413
oligodendrocyte cell fate commitment GO:0021779 5 0.397
Zebrafish
positive regulation of metabolic process GO:0009893 108 0.390
Worm
heart development GO:0007507 313 0.384
Zebrafish
neuron differentiation GO:0030182 353 0.383
transcription dna templated GO:0006351 181 0.379
Worm
heterocycle metabolic process GO:0046483 290 0.378
Worm
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.375
Worm
head development GO:0060322 303 0.353
regulation of nitrogen compound metabolic process GO:0051171 251 0.351
Worm
regulation of biosynthetic process GO:0009889 250 0.349
Worm
central nervous system neuron differentiation GO:0021953 74 0.345
glial cell differentiation GO:0010001 42 0.337
Zebrafish
organic cyclic compound metabolic process GO:1901360 301 0.332
Worm
cellular macromolecule metabolic process GO:0044260 391 0.329
Worm
gene expression GO:0010467 252 0.313
Worm
regulation of macromolecule biosynthetic process GO:0010556 225 0.312
Worm
central nervous system development GO:0007417 387 0.309
digestive tract development GO:0048565 265 0.302
Worm
cell fate specification GO:0001708 68 0.300
Zebrafish
specification of symmetry GO:0009799 204 0.299
Zebrafish
determination of left right symmetry GO:0007368 179 0.299
Zebrafish
cell motility GO:0048870 244 0.299
Zebrafish
rna metabolic process GO:0016070 219 0.298
Worm
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.294
Worm
neuron development GO:0048666 262 0.294
Zebrafish
lateral line ganglion development GO:0048890 2 0.288
cellular nitrogen compound biosynthetic process GO:0044271 218 0.284
Worm
brain development GO:0007420 293 0.281
embryonic organ development GO:0048568 381 0.266
Zebrafish
transcription from rna polymerase ii promoter GO:0006366 80 0.255
Worm
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.252
Worm
striated muscle cell differentiation GO:0051146 129 0.248
Zebrafish
embryo development ending in birth or egg hatching GO:0009792 271 0.243
tube morphogenesis GO:0035239 349 0.239
Zebrafish
larval development GO:0002164 2 0.239
regulation of developmental process GO:0050793 247 0.235
Zebrafish
pancreatic a cell development GO:0003322 2 0.233
central nervous system myelin formation GO:0032289 1 0.232
regulation of heart morphogenesis GO:2000826 17 0.221
Zebrafish
negative regulation of cellular process GO:0048523 283 0.211
epidermal cell fate specification GO:0009957 4 0.198
thyroid gland development GO:0030878 12 0.198
Zebrafish
cellular component assembly involved in morphogenesis GO:0010927 107 0.192
morphogenesis of an epithelium GO:0002009 333 0.184
Zebrafish
generation of neurons GO:0048699 385 0.183
locomotion GO:0040011 313 0.183
Zebrafish
regulation of rna metabolic process GO:0051252 224 0.182
Worm
cardiac chamber formation GO:0003207 4 0.182
Zebrafish
cellular component morphogenesis GO:0032989 336 0.180
Zebrafish
growth GO:0040007 174 0.179
Zebrafish
neuron projection morphogenesis GO:0048812 161 0.177
Zebrafish
cellular component movement GO:0006928 335 0.176
Zebrafish
spinal cord oligodendrocyte cell differentiation GO:0021529 5 0.175
Zebrafish
negative regulation of cell differentiation GO:0045596 46 0.171
positive regulation of gene expression GO:0010628 71 0.170
Worm
macromolecule biosynthetic process GO:0009059 227 0.169
Worm
chordate embryonic development GO:0043009 271 0.167
regulation of primary metabolic process GO:0080090 311 0.167
Worm
optomotor response GO:0071632 1 0.160
cell fate commitment GO:0045165 99 0.160
Zebrafish
positive regulation of cellular metabolic process GO:0031325 94 0.160
Worm
determination of bilateral symmetry GO:0009855 204 0.155
Zebrafish
positive regulation of nucleic acid templated transcription GO:1903508 57 0.151
Worm
localization of cell GO:0051674 244 0.150
Zebrafish
determination of heart left right asymmetry GO:0061371 117 0.150
Zebrafish
digestive system development GO:0055123 289 0.147
Worm
gland development GO:0048732 143 0.146
Zebrafish
forebrain development GO:0030900 96 0.142
dorsal ventral pattern formation GO:0009953 125 0.140
neuron projection guidance GO:0097485 86 0.139
Zebrafish
cell projection organization GO:0030030 284 0.137
Zebrafish
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.134
regulation of circadian rhythm GO:0042752 4 0.133
regulation of cell development GO:0060284 100 0.131
negative regulation of biological process GO:0048519 304 0.130
pancreas development GO:0031016 84 0.128
Zebrafish
biosynthetic process GO:0009058 294 0.125
Worm
glial cell development GO:0021782 20 0.123
Zebrafish
organic substance biosynthetic process GO:1901576 289 0.122
Worm
neural crest cell differentiation GO:0014033 72 0.122
glial cell fate specification GO:0021780 4 0.121
Zebrafish
regulation of nervous system development GO:0051960 90 0.118
gliogenesis GO:0042063 45 0.117
Zebrafish
endoderm development GO:0007492 49 0.114
peripheral nervous system development GO:0007422 55 0.112
Zebrafish
axonogenesis GO:0007409 152 0.112
Zebrafish
positive regulation of macromolecule metabolic process GO:0010604 93 0.111
Worm
negative regulation of developmental process GO:0051093 65 0.110
cell fate specification involved in pattern specification GO:0060573 3 0.110
regulation of blood pressure GO:0008217 1 0.109
heart looping GO:0001947 94 0.109
Zebrafish
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.108
Worm
gabaergic neuron differentiation GO:0097154 2 0.105
ventral spinal cord interneuron fate commitment GO:0060579 3 0.105
pharyngeal muscle development GO:0043282 4 0.105
Worm
embryonic heart tube development GO:0035050 133 0.103
Zebrafish
central nervous system myelination GO:0022010 2 0.102
striated muscle tissue development GO:0014706 110 0.101
Zebrafish
response to stress GO:0006950 263 0.101
positive regulation of rna metabolic process GO:0051254 59 0.100
Worm
cell morphogenesis GO:0000902 289 0.100
Zebrafish
regulation of neurogenesis GO:0050767 87 0.098
glial cell fate commitment GO:0021781 6 0.098
Zebrafish
single organism metabolic process GO:0044710 217 0.098
ear morphogenesis GO:0042471 64 0.094
axon development GO:0061564 166 0.093
Zebrafish
regionalization GO:0003002 274 0.092
regulation of neuron differentiation GO:0045664 56 0.092
glial cell migration GO:0008347 3 0.091
Zebrafish
positive regulation of biosynthetic process GO:0009891 68 0.091
Worm
multicellular organism growth GO:0035264 4 0.091
cell migration GO:0016477 237 0.089
Zebrafish
regulation of multicellular organism growth GO:0040014 4 0.089
pigmentation GO:0043473 85 0.089
heart morphogenesis GO:0003007 156 0.088
Zebrafish
stem cell differentiation GO:0048863 117 0.088
hatching gland development GO:0048785 3 0.087
astrocyte differentiation GO:0048708 1 0.086
pituitary gland development GO:0021983 16 0.085
diencephalon development GO:0021536 58 0.084
midbrain development GO:0030901 28 0.083
reproduction GO:0000003 40 0.082
negative regulation of gene expression GO:0010629 65 0.082
endocrine system development GO:0035270 65 0.081
Zebrafish
gastrulation GO:0007369 208 0.080
epithelial tube morphogenesis GO:0060562 148 0.079
Zebrafish
taxis GO:0042330 109 0.078
Zebrafish
regulation of response to stimulus GO:0048583 269 0.078
endocrine pancreas development GO:0031018 27 0.078
Zebrafish
pharyngeal system development GO:0060037 18 0.077
cell proliferation GO:0008283 80 0.076
Zebrafish
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.074
Zebrafish
bmp signaling pathway GO:0030509 52 0.074
response to chemical GO:0042221 320 0.074
Zebrafish
motor neuron axon guidance GO:0008045 23 0.074
Zebrafish
neuron fate specification GO:0048665 20 0.073
cardiac muscle tissue development GO:0048738 48 0.073
Zebrafish
single organism organelle organization GO:1902589 199 0.072
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.072
photoreceptor cell fate commitment GO:0046552 1 0.071
neural tube development GO:0021915 62 0.071
muscle structure development GO:0061061 196 0.070
Zebrafish Worm
developmental pigmentation GO:0048066 48 0.069
embryonic organ morphogenesis GO:0048562 274 0.068
Zebrafish
cell part morphogenesis GO:0032990 246 0.068
Zebrafish
cell morphogenesis involved in differentiation GO:0000904 195 0.068
Zebrafish
morphogenesis of an epithelial sheet GO:0002011 49 0.067
anterior commissure morphogenesis GO:0021960 3 0.067
skeletal system development GO:0001501 181 0.066
regulation of cardiac chamber formation GO:1901210 2 0.066
Zebrafish
hindbrain development GO:0030902 91 0.064
organelle assembly GO:0070925 110 0.064
blood circulation GO:0008015 87 0.064
regulation of cell communication GO:0010646 232 0.063
negative regulation of rna metabolic process GO:0051253 48 0.061
regulation of biological quality GO:0065008 263 0.061
negative regulation of epithelial cell proliferation GO:0050680 1 0.061
forebrain neuron fate commitment GO:0021877 1 0.059
axon ensheathment in central nervous system GO:0032291 2 0.059
cellular response to nutrient levels GO:0031669 2 0.058
cardiac muscle cell differentiation GO:0055007 30 0.058
Zebrafish
floor plate morphogenesis GO:0033505 12 0.057
embryonic heart tube morphogenesis GO:0003143 108 0.057
Zebrafish
cell projection morphogenesis GO:0048858 244 0.056
Zebrafish
forebrain regionalization GO:0021871 4 0.056
negative regulation of multicellular organismal process GO:0051241 69 0.056
water homeostasis GO:0030104 4 0.055
angiogenesis GO:0001525 158 0.055
digestive tract morphogenesis GO:0048546 231 0.055
abducens nucleus development GO:0021742 2 0.055
maintenance of location GO:0051235 4 0.054
aging GO:0007568 2 0.054
muscle organ development GO:0007517 101 0.054
Worm
cardiac chamber development GO:0003205 19 0.053
Zebrafish
cardiocyte differentiation GO:0035051 44 0.053
Zebrafish
regulation of cellular amino acid metabolic process GO:0006521 0 0.052
actomyosin structure organization GO:0031032 53 0.052
reproductive process GO:0022414 40 0.052
pancreatic d cell differentiation GO:0003311 2 0.051
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.051
neuroepithelial cell differentiation GO:0060563 26 0.051
positive regulation of stem cell proliferation GO:2000648 1 0.050
circulatory system process GO:0003013 87 0.050
ventral spinal cord interneuron specification GO:0021521 3 0.049
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.049
ectodermal placode development GO:0071696 37 0.049
vasculature development GO:0001944 278 0.047
fourth ventricle development GO:0021592 8 0.047
pharynx development GO:0060465 5 0.047
Worm
myelin assembly GO:0032288 1 0.046
regulation of locomotion GO:0040012 55 0.046
negative regulation of signaling GO:0023057 96 0.046
multicellular organism reproduction GO:0032504 35 0.046
endocrine process GO:0050886 2 0.046
midbrain hindbrain boundary morphogenesis GO:0021555 5 0.045
female sex differentiation GO:0046660 4 0.045
regulation of cellular component movement GO:0051270 55 0.044
regulation of signal transduction GO:0009966 225 0.044
regulation of localization GO:0032879 104 0.043
multi organism process GO:0051704 134 0.043
cell proliferation in forebrain GO:0021846 3 0.042
system process GO:0003008 185 0.042
negative regulation of macromolecule metabolic process GO:0010605 76 0.042
epithelial cell development GO:0002064 42 0.041
mesenchymal cell differentiation GO:0048762 87 0.041
cellular response to external stimulus GO:0071496 2 0.040
renal system development GO:0072001 94 0.040
pigment cell differentiation GO:0050931 38 0.040
cell surface receptor signaling pathway GO:0007166 325 0.040
macromolecular complex subunit organization GO:0043933 74 0.039
negative regulation of cell communication GO:0010648 96 0.039
sympathetic nervous system development GO:0048485 3 0.039
schwann cell differentiation GO:0014037 9 0.039
Zebrafish
pancreatic d cell development GO:0003324 1 0.038
neuroblast fate determination GO:0007400 1 0.038
axial mesoderm morphogenesis GO:0048319 8 0.038
post embryonic morphogenesis GO:0009886 4 0.038
regulation of rho protein signal transduction GO:0035023 2 0.037
stem cell maintenance GO:0019827 4 0.037
lipid storage GO:0019915 1 0.036
skeletal muscle organ development GO:0060538 78 0.036
camera type eye morphogenesis GO:0048593 108 0.036
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.036
Worm
schwann cell development GO:0014044 9 0.036
Zebrafish
negative regulation of stem cell differentiation GO:2000737 2 0.035
positive regulation of rna biosynthetic process GO:1902680 57 0.035
Worm
response to external stimulus GO:0009605 264 0.035
Zebrafish
regulation of cell morphogenesis GO:0022604 42 0.035
embryonic viscerocranium morphogenesis GO:0048703 52 0.035
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.035
neural crest cell migration GO:0001755 42 0.035
forebrain generation of neurons GO:0021872 14 0.035
organelle organization GO:0006996 227 0.034
spinal cord association neuron differentiation GO:0021527 1 0.034
negative regulation of embryonic development GO:0045992 11 0.034
positive regulation of catabolic process GO:0009896 4 0.034
antimicrobial humoral response GO:0019730 2 0.034
oligodendrocyte development GO:0014003 7 0.033
cell migration involved in gastrulation GO:0042074 79 0.032
compound eye development GO:0048749 2 0.032
nephron tubule morphogenesis GO:0072078 1 0.032
positive regulation of multicellular organismal process GO:0051240 52 0.032
type b pancreatic cell development GO:0003323 4 0.032
regulation of stem cell proliferation GO:0072091 2 0.032
negative regulation of transcription dna templated GO:0045892 45 0.032
notochord development GO:0030903 54 0.031
formation of primary germ layer GO:0001704 62 0.031
gastrulation with mouth forming second GO:0001702 44 0.031
convergent extension GO:0060026 118 0.031
heart contraction GO:0060047 71 0.031
positive regulation of epithelial cell differentiation GO:0030858 2 0.031
defense response GO:0006952 47 0.030
regulation of cell migration GO:0030334 40 0.030
oxoacid metabolic process GO:0043436 31 0.029
phosphate containing compound metabolic process GO:0006796 108 0.029
positive regulation of leukocyte differentiation GO:1902107 1 0.029
cellular ketone metabolic process GO:0042180 11 0.029
behavior GO:0007610 74 0.029
aorta development GO:0035904 4 0.028
spinal cord motor neuron differentiation GO:0021522 26 0.028
negative regulation of biosynthetic process GO:0009890 55 0.028
cardiac chamber morphogenesis GO:0003206 12 0.028
Zebrafish
negative regulation of cellular metabolic process GO:0031324 77 0.028
positive regulation of cellular biosynthetic process GO:0031328 68 0.028
Worm
stem cell fate determination GO:0048867 1 0.028
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.028
cranial ganglion development GO:0061550 3 0.027
keratinocyte differentiation GO:0030216 0 0.027
epithelial cell differentiation GO:0030855 116 0.027
positive regulation of transcription dna templated GO:0045893 57 0.027
Worm
organ growth GO:0035265 12 0.027
Zebrafish
guanosine containing compound metabolic process GO:1901068 4 0.026
endoderm formation GO:0001706 29 0.026
mitotic dna integrity checkpoint GO:0044774 4 0.026
embryonic limb morphogenesis GO:0030326 2 0.026
chemotaxis GO:0006935 104 0.026
Zebrafish
regulation of cell motility GO:2000145 46 0.025
locomotor rhythm GO:0045475 3 0.025
response to biotic stimulus GO:0009607 97 0.025
regulation of cell proliferation GO:0042127 37 0.025
regulation of neural precursor cell proliferation GO:2000177 3 0.025
cellular response to extracellular stimulus GO:0031668 2 0.025
sensory organ morphogenesis GO:0090596 200 0.025
regulation of systemic arterial blood pressure GO:0003073 1 0.025
positive regulation of nervous system development GO:0051962 25 0.025
alpha amino acid metabolic process GO:1901605 3 0.025
circadian rhythm GO:0007623 19 0.025
multi organism reproductive process GO:0044703 36 0.025
ectoderm formation GO:0001705 2 0.025
blood vessel morphogenesis GO:0048514 216 0.025
dorsal spinal cord development GO:0021516 1 0.025
muscle cell proliferation GO:0033002 7 0.025
Zebrafish
negative regulation of response to stimulus GO:0048585 104 0.024
amine metabolic process GO:0009308 2 0.024
wnt signaling pathway GO:0016055 80 0.024
mesenchymal cell development GO:0014031 78 0.024
signal transduction GO:0007165 455 0.024
sensory organ development GO:0007423 393 0.024
negative regulation of signal transduction GO:0009968 94 0.024
eye development GO:0001654 277 0.024
ameboidal type cell migration GO:0001667 143 0.023
developmental process involved in reproduction GO:0003006 27 0.023
regulation of signaling GO:0023051 235 0.023
regulation of system process GO:0044057 40 0.023
organic acid metabolic process GO:0006082 31 0.023
neural tube patterning GO:0021532 33 0.023
gtp metabolic process GO:0046039 4 0.023
camera type eye development GO:0043010 222 0.023
gtp catabolic process GO:0006184 2 0.023
regulation of cellular ketone metabolic process GO:0010565 7 0.023
positive regulation of cellular catabolic process GO:0031331 3 0.023
neuromast development GO:0048884 46 0.023
negative regulation of cellular biosynthetic process GO:0031327 55 0.023
regulation of epithelial cell proliferation GO:0050678 3 0.023
neural plate pattern specification GO:0060896 12 0.022
negative regulation of nuclear division GO:0051784 3 0.022
cell cycle GO:0007049 93 0.022
regulation of cellular component organization GO:0051128 86 0.022
cytoskeleton organization GO:0007010 96 0.022
striated muscle cell proliferation GO:0014855 7 0.022
Zebrafish
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.022
inner ear receptor cell development GO:0060119 20 0.022
ectodermal placode formation GO:0060788 26 0.021
negative regulation of cellular response to growth factor stimulus GO:0090288 9 0.021
cell proliferation in hindbrain GO:0021534 4 0.021
defense response to fungus GO:0050832 2 0.021
axon guidance GO:0007411 86 0.021
Zebrafish
retina morphogenesis in camera type eye GO:0060042 79 0.021
carboxylic acid metabolic process GO:0019752 22 0.021
regulation of protein ubiquitination GO:0031396 3 0.021
somatic muscle development GO:0007525 4 0.020
facial nucleus development GO:0021754 7 0.020
cellular response to chemical stimulus GO:0070887 157 0.020
embryonic retina morphogenesis in camera type eye GO:0060059 22 0.020
determination of dorsal ventral asymmetry GO:0048262 34 0.020
regulation of endodermal cell fate specification GO:0042663 15 0.020
death GO:0016265 121 0.020
positive regulation of nucleotide catabolic process GO:0030813 1 0.020
radial glial cell differentiation GO:0060019 2 0.020
skeletal muscle tissue development GO:0007519 67 0.020
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.020
regulation of cellular amine metabolic process GO:0033238 0 0.020
regulation of binding GO:0051098 3 0.020
urogenital system development GO:0001655 97 0.019
cell fate commitment involved in pattern specification GO:0060581 6 0.019
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.019
ectodermal placode morphogenesis GO:0071697 32 0.019
cellular amine metabolic process GO:0044106 2 0.019
cellular response to growth factor stimulus GO:0071363 39 0.019
metencephalon development GO:0022037 27 0.019
regulation of protein complex assembly GO:0043254 3 0.019
regulation of neuron projection development GO:0010975 40 0.019
catecholamine biosynthetic process GO:0042423 2 0.019
neuroblast fate commitment GO:0014017 1 0.019
protein localization to nucleus GO:0034504 3 0.018
nephron epithelium morphogenesis GO:0072088 1 0.018
otic placode formation GO:0043049 23 0.018
epiboly GO:0090504 41 0.018
endothelial cell fate commitment GO:0060839 3 0.018
cellular response to starvation GO:0009267 1 0.018
myofibril assembly GO:0030239 48 0.018
developmental programmed cell death GO:0010623 4 0.018
gamete generation GO:0007276 33 0.018
ear development GO:0043583 127 0.018
regulation of dendrite morphogenesis GO:0048814 3 0.018
embryonic skeletal system morphogenesis GO:0048704 93 0.018
skin development GO:0043588 54 0.018
negative regulation of intracellular protein transport GO:0090317 3 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.018
modification dependent protein catabolic process GO:0019941 3 0.018
regulation of endothelial cell proliferation GO:0001936 1 0.018
nephron development GO:0072006 31 0.018
pectoral fin development GO:0033339 50 0.017
cell cycle g1 s phase transition GO:0044843 1 0.017
enteric nervous system development GO:0048484 12 0.017
regulation of organ morphogenesis GO:2000027 35 0.017
Zebrafish
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.017
cilium or flagellum dependent cell motility GO:0001539 4 0.017
forebrain cell migration GO:0021885 1 0.017
appendage morphogenesis GO:0035107 56 0.017
cell cycle arrest GO:0007050 1 0.017
single organism reproductive process GO:0044702 40 0.017
negative regulation of mesodermal cell fate specification GO:0042662 3 0.017
developmental growth GO:0048589 166 0.017
positive regulation of cell cycle GO:0045787 3 0.017
development of primary female sexual characteristics GO:0046545 4 0.017
chromosome organization GO:0051276 31 0.017
meiotic nuclear division GO:0007126 4 0.017
embryonic cranial skeleton morphogenesis GO:0048701 90 0.017
multicellular organismal reproductive process GO:0048609 35 0.017
axial mesodermal cell fate specification GO:0048327 3 0.017
semicircular canal development GO:0060872 24 0.017
enzyme linked receptor protein signaling pathway GO:0007167 106 0.016
negative regulation of gliogenesis GO:0014014 1 0.016
germ line stem cell maintenance GO:0030718 2 0.016
skeletal system morphogenesis GO:0048705 102 0.016
regulation of oligodendrocyte differentiation GO:0048713 1 0.016
embryonic camera type eye morphogenesis GO:0048596 19 0.016
regulation of sodium ion transport GO:0002028 2 0.016
organonitrogen compound metabolic process GO:1901564 74 0.016
establishment of protein localization to organelle GO:0072594 4 0.016
regulation of nucleoside metabolic process GO:0009118 2 0.016
rhythmic process GO:0048511 21 0.016
regulation of cellular protein metabolic process GO:0032268 52 0.016
limbic system development GO:0021761 16 0.016
neural nucleus development GO:0048857 15 0.016
regulation of gtp catabolic process GO:0033124 2 0.016
cellular amino acid metabolic process GO:0006520 7 0.016
response to lipid GO:0033993 60 0.016
proximal distal pattern formation GO:0009954 1 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.016
regulation of cytokine production GO:0001817 3 0.015
negative regulation of neurogenesis GO:0050768 20 0.015
positive regulation of multi organism process GO:0043902 3 0.015
stem cell fate commitment GO:0048865 1 0.015
canonical wnt signaling pathway GO:0060070 48 0.015
central nervous system neuron development GO:0021954 29 0.015
single organism nuclear import GO:1902593 3 0.015
somitogenesis GO:0001756 87 0.015
regulation of dendrite development GO:0050773 3 0.015
renal tubule morphogenesis GO:0061333 1 0.015
ventricular system development GO:0021591 12 0.015
embryonic skeletal system development GO:0048706 97 0.015
regulation of cellular response to growth factor stimulus GO:0090287 35 0.015
fin regeneration GO:0031101 51 0.015
response to external biotic stimulus GO:0043207 97 0.015
negative regulation of rna biosynthetic process GO:1902679 45 0.015
positive regulation of gliogenesis GO:0014015 2 0.015
nucleocytoplasmic transport GO:0006913 4 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.014
catecholamine metabolic process GO:0006584 2 0.014
cellular amide metabolic process GO:0043603 4 0.014
stem cell proliferation GO:0072089 4 0.014
endodermal cell fate specification GO:0001714 17 0.014
positive regulation of transport GO:0051050 2 0.014
regulation of glial cell differentiation GO:0045685 4 0.014
sensory system development GO:0048880 76 0.014
proteasomal protein catabolic process GO:0010498 2 0.014
melanocyte differentiation GO:0030318 26 0.014
fin development GO:0033333 77 0.014
eye photoreceptor cell differentiation GO:0001754 45 0.014
response to other organism GO:0051707 97 0.014
protein import into nucleus GO:0006606 3 0.014
positive regulation of gtp catabolic process GO:0033126 1 0.014
protein acetylation GO:0006473 2 0.014
phosphatidylinositol mediated signaling GO:0048015 2 0.014
nuclear import GO:0051170 3 0.014
intracellular signal transduction GO:0035556 85 0.014

nkx2.2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.043
bone development disease DOID:0080006 0 0.022
bone disease DOID:0080001 0 0.022
musculoskeletal system disease DOID:17 0 0.022
connective tissue disease DOID:65 0 0.022
disease of cellular proliferation DOID:14566 0 0.015