Danio rerio

25 known processes

ephx2

epoxide hydrolase 2, cytoplasmic

(Aliases: sb:cb523,zgc:101645)

ephx2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.108
aging GO:0007568 2 0.101
maintenance of location GO:0051235 4 0.061
multicellular organism growth GO:0035264 4 0.059
lipid storage GO:0019915 1 0.059
amine metabolic process GO:0009308 2 0.045
regulation of multicellular organism growth GO:0040014 4 0.044
regulation of biological quality GO:0065008 263 0.041
Mouse
positive regulation of biological process GO:0048518 253 0.040
Mouse
cellular component movement GO:0006928 335 0.039
cognition GO:0050890 1 0.037
signal transduction GO:0007165 455 0.037
cell substrate adhesion GO:0031589 4 0.036
regulation of cell activation GO:0050865 1 0.036
meiotic nuclear division GO:0007126 4 0.036
negative regulation of biological process GO:0048519 304 0.036
cellular amine metabolic process GO:0044106 2 0.036
regulation of cellular amine metabolic process GO:0033238 0 0.035
regulation of cytokine production GO:0001817 3 0.035
stem cell maintenance GO:0019827 4 0.034
response to nutrient GO:0007584 3 0.034
positive regulation of cell activation GO:0050867 1 0.034
angiogenesis GO:0001525 158 0.034
cellular ketone metabolic process GO:0042180 11 0.034
regulation of inflammatory response GO:0050727 2 0.034
single organism organelle organization GO:1902589 199 0.033
nitrogen compound metabolic process GO:0006807 319 0.033
cellular component morphogenesis GO:0032989 336 0.033
regulation of cellular ketone metabolic process GO:0010565 7 0.033
cell projection morphogenesis GO:0048858 244 0.033
positive regulation of cell cycle GO:0045787 3 0.033
regulation of establishment of protein localization GO:0070201 4 0.032
generation of neurons GO:0048699 385 0.032
positive regulation of transport GO:0051050 2 0.031
blood vessel development GO:0001568 246 0.031
cell projection organization GO:0030030 284 0.031
vasculature development GO:0001944 278 0.031
mononuclear cell proliferation GO:0032943 1 0.030
organonitrogen compound metabolic process GO:1901564 74 0.030
leukocyte proliferation GO:0070661 1 0.030
locomotion GO:0040011 313 0.030
single organism localization GO:1902578 225 0.030
system process GO:0003008 185 0.030
regulation of cellular amino acid metabolic process GO:0006521 0 0.030
regulation of synapse organization GO:0050807 3 0.029
endosomal transport GO:0016197 2 0.029
stem cell proliferation GO:0072089 4 0.029
localization of cell GO:0051674 244 0.029
digestive tract morphogenesis GO:0048546 231 0.029
regulation of developmental process GO:0050793 247 0.029
positive regulation of cellular component biogenesis GO:0044089 3 0.029
morphogenesis of an epithelium GO:0002009 333 0.029
single organism metabolic process GO:0044710 217 0.028
Mouse
regulation of signaling GO:0023051 235 0.027
protein metabolic process GO:0019538 183 0.026
lymphocyte proliferation GO:0046651 1 0.026
positive regulation of secretion GO:0051047 1 0.026
phagocytosis GO:0006909 3 0.026
negative regulation of cellular process GO:0048523 283 0.026
cellular macromolecule metabolic process GO:0044260 391 0.026
small molecule metabolic process GO:0044281 77 0.025
Mouse
cellular component biogenesis GO:0044085 178 0.025
organic acid metabolic process GO:0006082 31 0.025
transport GO:0006810 220 0.025
regulation of cellular metabolic process GO:0031323 320 0.025
cellular amino acid metabolic process GO:0006520 7 0.025
brain development GO:0007420 293 0.025
cell part morphogenesis GO:0032990 246 0.025
hemopoiesis GO:0030097 183 0.024
cellular nitrogen compound metabolic process GO:0034641 290 0.024
germ line stem cell maintenance GO:0030718 2 0.024
heterocycle metabolic process GO:0046483 290 0.024
response to wounding GO:0009611 116 0.024
positive regulation of secretion by cell GO:1903532 1 0.024
synaptic growth at neuromuscular junction GO:0051124 2 0.024
positive regulation of immune effector process GO:0002699 3 0.024
regulation of protein transport GO:0051223 3 0.024
regulation of metabolic process GO:0019222 359 0.024
Mouse
central nervous system development GO:0007417 387 0.024
regulation of cell communication GO:0010646 232 0.024
muscle structure development GO:0061061 196 0.024
convergent extension GO:0060026 118 0.024
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.024
regulation of multicellular organismal development GO:2000026 223 0.023
regulation of reproductive process GO:2000241 4 0.023
response to stress GO:0006950 263 0.023
establishment of localization GO:0051234 244 0.023
protein targeting to nucleus GO:0044744 3 0.023
regulation of cell shape GO:0008360 1 0.023
stem cell division GO:0017145 1 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.023
guanosine containing compound metabolic process GO:1901068 4 0.023
cell migration GO:0016477 237 0.023
regulation of macromolecule metabolic process GO:0060255 317 0.023
Mouse
cellular response to nutrient levels GO:0031669 2 0.023
nucleobase containing compound metabolic process GO:0006139 274 0.022
regulation of cytoplasmic transport GO:1903649 4 0.022
positive regulation of cytokine production GO:0001819 2 0.022
response to external stimulus GO:0009605 264 0.022
compound eye development GO:0048749 2 0.022
response to chemical GO:0042221 320 0.022
embryo development ending in birth or egg hatching GO:0009792 271 0.022
neuron projection development GO:0031175 180 0.022
immune system development GO:0002520 191 0.022
nucleocytoplasmic transport GO:0006913 4 0.022
neuron differentiation GO:0030182 353 0.022
cellular response to extracellular stimulus GO:0031668 2 0.022
organic substance biosynthetic process GO:1901576 289 0.022
regulation of response to stimulus GO:0048583 269 0.021
regulation of protein complex assembly GO:0043254 3 0.021
regulation of synapse assembly GO:0051963 3 0.021
positive regulation of cellular amine metabolic process GO:0033240 0 0.021
protein acetylation GO:0006473 2 0.021
glucose homeostasis GO:0042593 1 0.021
cell morphogenesis GO:0000902 289 0.021
regulation of protein catabolic process GO:0042176 1 0.021
response to carbohydrate GO:0009743 3 0.021
actin filament polymerization GO:0030041 2 0.021
homeostatic process GO:0042592 142 0.021
Mouse
regulation of epithelial cell proliferation GO:0050678 3 0.021
cellular component assembly GO:0022607 170 0.021
negative regulation of protein phosphorylation GO:0001933 4 0.021
neuron projection morphogenesis GO:0048812 161 0.021
striated muscle tissue development GO:0014706 110 0.020
positive regulation of protein complex assembly GO:0031334 2 0.020
establishment of protein localization to organelle GO:0072594 4 0.020
regulation of blood vessel size GO:0050880 2 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.020
protein localization to nucleus GO:0034504 3 0.020
digestive system development GO:0055123 289 0.020
response to alkaloid GO:0043279 2 0.020
cellular aromatic compound metabolic process GO:0006725 295 0.020
single organism transport GO:0044765 206 0.020
actin polymerization or depolymerization GO:0008154 2 0.020
regulation of gene expression GO:0010468 265 0.020
Mouse
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.020
cell matrix adhesion GO:0007160 4 0.020
developmental growth GO:0048589 166 0.019
protein polymerization GO:0051258 4 0.019
ribonucleoside monophosphate catabolic process GO:0009158 4 0.019
cellular component disassembly GO:0022411 1 0.019
membrane fusion GO:0061025 2 0.019
positive regulation of map kinase activity GO:0043406 3 0.019
peptide transport GO:0015833 1 0.019
cell motility GO:0048870 244 0.019
atp catabolic process GO:0006200 4 0.019
response to glucose GO:0009749 3 0.019
negative regulation of cytokine production GO:0001818 1 0.019
nucleic acid metabolic process GO:0090304 244 0.019
astrocyte differentiation GO:0048708 1 0.019
oxoacid metabolic process GO:0043436 31 0.019
digestive tract development GO:0048565 265 0.019
internal peptidyl lysine acetylation GO:0018393 2 0.019
blood vessel morphogenesis GO:0048514 216 0.019
lateral inhibition GO:0046331 1 0.019
gastrulation GO:0007369 208 0.019
carboxylic acid metabolic process GO:0019752 22 0.019
regulation of protein targeting GO:1903533 2 0.019
nucleic acid templated transcription GO:0097659 181 0.019
regulation of multicellular organismal process GO:0051239 277 0.019
regulation of muscle contraction GO:0006937 3 0.018
single organism nuclear import GO:1902593 3 0.018
immune system process GO:0002376 241 0.018
spermatid development GO:0007286 2 0.018
organelle organization GO:0006996 227 0.018
cellular response to external stimulus GO:0071496 2 0.018
rna biosynthetic process GO:0032774 181 0.018
chemotaxis GO:0006935 104 0.018
eye development GO:0001654 277 0.018
tissue remodeling GO:0048771 4 0.018
response to hexose GO:0009746 3 0.018
cortical cytoskeleton organization GO:0030865 1 0.018
hepaticobiliary system development GO:0061008 98 0.017
regulation of stem cell proliferation GO:0072091 2 0.017
chemosensory behavior GO:0007635 1 0.017
regulation of intracellular protein transport GO:0033157 3 0.017
regulation of metal ion transport GO:0010959 4 0.017
tube morphogenesis GO:0035239 349 0.017
biosynthetic process GO:0009058 294 0.017
nuclear transport GO:0051169 4 0.017
gtp metabolic process GO:0046039 4 0.017
peptidyl lysine acetylation GO:0018394 2 0.017
mitochondrion organization GO:0007005 4 0.017
cytokinesis GO:0000910 3 0.017
protein homooligomerization GO:0051260 3 0.017
protein import into nucleus GO:0006606 3 0.017
single fertilization GO:0007338 3 0.017
internal protein amino acid acetylation GO:0006475 2 0.017
nucleoside monophosphate catabolic process GO:0009125 4 0.017
carbohydrate homeostasis GO:0033500 1 0.016
exocytosis GO:0006887 1 0.016
hormone transport GO:0009914 2 0.016
protein import GO:0017038 3 0.016
cell surface receptor signaling pathway GO:0007166 325 0.016
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.016
heterocycle biosynthetic process GO:0018130 215 0.016
meiotic cell cycle process GO:1903046 3 0.016
regeneration GO:0031099 91 0.016
intracellular signal transduction GO:0035556 85 0.016
positive regulation of catabolic process GO:0009896 4 0.016
response to monosaccharide GO:0034284 3 0.016
rna metabolic process GO:0016070 219 0.016
positive regulation of cytoskeleton organization GO:0051495 3 0.016
growth GO:0040007 174 0.016
taxis GO:0042330 109 0.016
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.016
single organism membrane fusion GO:0044801 2 0.016
protein complex disassembly GO:0043241 1 0.016
sensory organ development GO:0007423 393 0.016
purine nucleoside monophosphate catabolic process GO:0009128 4 0.016
phosphorus metabolic process GO:0006793 109 0.016
regulation of sodium ion transport GO:0002028 2 0.016
response to abiotic stimulus GO:0009628 122 0.015
head development GO:0060322 303 0.015
wound healing GO:0042060 90 0.015
gtp catabolic process GO:0006184 2 0.015
regulation of protein localization to nucleus GO:1900180 2 0.015
neuroblast proliferation GO:0007405 2 0.015
cellular nitrogen compound biosynthetic process GO:0044271 218 0.015
skeletal system development GO:0001501 181 0.015
protein acylation GO:0043543 3 0.015
positive regulation of cellular catabolic process GO:0031331 3 0.015
production of molecular mediator of immune response GO:0002440 2 0.015
autophagy GO:0006914 4 0.015
positive regulation of cellular process GO:0048522 201 0.015
gene expression GO:0010467 252 0.015
Mouse
ubiquitin dependent protein catabolic process GO:0006511 3 0.015
female sex differentiation GO:0046660 4 0.015
peptidyl serine modification GO:0018209 2 0.015
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.015
phosphate containing compound metabolic process GO:0006796 108 0.015
regulation of biosynthetic process GO:0009889 250 0.015
guanosine containing compound catabolic process GO:1901069 2 0.015
rna localization GO:0006403 4 0.015
hormone secretion GO:0046879 2 0.015
regulation of tube size GO:0035150 2 0.015
macromolecular complex disassembly GO:0032984 1 0.015
modification dependent macromolecule catabolic process GO:0043632 3 0.015
spermatid differentiation GO:0048515 2 0.015
nuclear import GO:0051170 3 0.014
cellular macromolecule biosynthetic process GO:0034645 224 0.014
regulation of hormone secretion GO:0046883 2 0.014
cell morphogenesis involved in differentiation GO:0000904 195 0.014
embryonic organ development GO:0048568 381 0.014
organic cyclic compound biosynthetic process GO:1901362 223 0.014
regulation of nitrogen compound metabolic process GO:0051171 251 0.014
somatic muscle development GO:0007525 4 0.014
proteasomal protein catabolic process GO:0010498 2 0.014
regulation of rna metabolic process GO:0051252 224 0.014
heart development GO:0007507 313 0.014
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.014
negative regulation of synapse assembly GO:0051964 2 0.014
protein modification process GO:0036211 100 0.014
cellular protein catabolic process GO:0044257 4 0.014
axonogenesis GO:0007409 152 0.014
negative regulation of reproductive process GO:2000242 3 0.014
regulation of macromolecule biosynthetic process GO:0010556 225 0.014
regulation of rna biosynthetic process GO:2001141 213 0.014
axon development GO:0061564 166 0.014
cellular response to starvation GO:0009267 1 0.014
erk1 and erk2 cascade GO:0070371 4 0.014
adherens junction organization GO:0034332 4 0.014
positive regulation of cell adhesion GO:0045785 1 0.014
regulation of stem cell differentiation GO:2000736 4 0.014
small molecule catabolic process GO:0044282 3 0.014
positive regulation of inflammatory response GO:0050729 1 0.014
transcription dna templated GO:0006351 181 0.014
macromolecule modification GO:0043412 111 0.013
camera type eye development GO:0043010 222 0.013
determination of bilateral symmetry GO:0009855 204 0.013
multicellular organismal metabolic process GO:0044236 2 0.013
organic cyclic compound metabolic process GO:1901360 301 0.013
Mouse
regulation of binding GO:0051098 3 0.013
aromatic compound biosynthetic process GO:0019438 217 0.013
negative regulation of ras protein signal transduction GO:0046580 1 0.013
peptidyl threonine phosphorylation GO:0018107 1 0.013
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.013
negative regulation of response to stimulus GO:0048585 104 0.013
ion transport GO:0006811 114 0.013
response to organic substance GO:0010033 153 0.013
smooth muscle contraction GO:0006939 2 0.013
cellular protein metabolic process GO:0044267 129 0.013
regulation of nucleoside metabolic process GO:0009118 2 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.013
negative regulation of protein transport GO:0051224 3 0.013
cellular response to biotic stimulus GO:0071216 3 0.013
i kappab kinase nf kappab signaling GO:0007249 4 0.013
canonical wnt signaling pathway GO:0060070 48 0.013
regulation of dna replication GO:0006275 3 0.013
regulation of primary metabolic process GO:0080090 311 0.013
Mouse
negative regulation of epithelial cell proliferation GO:0050680 1 0.013
activation of mapk activity GO:0000187 3 0.013
muscle cell differentiation GO:0042692 139 0.013
regulation of protein import into nucleus GO:0042306 2 0.013
regulation of nucleocytoplasmic transport GO:0046822 2 0.013
negative regulation of protein kinase activity GO:0006469 4 0.013
regulation of signal transduction GO:0009966 225 0.013
regulation of gtpase activity GO:0043087 2 0.013
negative regulation of signal transduction GO:0009968 94 0.013
regulation of autophagy GO:0010506 3 0.013
negative regulation of mapk cascade GO:0043409 4 0.013
negative regulation of cell communication GO:0010648 96 0.013
regulation of cellular biosynthetic process GO:0031326 245 0.013
negative regulation of signaling GO:0023057 96 0.013
regulation of nucleotide catabolic process GO:0030811 2 0.013
membrane invagination GO:0010324 1 0.013
cell substrate junction assembly GO:0007044 2 0.013
modification dependent protein catabolic process GO:0019941 3 0.012
protein dephosphorylation GO:0006470 3 0.012
actin cytoskeleton organization GO:0030036 63 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.012
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.012
response to vitamin GO:0033273 3 0.012
regulation of organelle assembly GO:1902115 4 0.012
adult behavior GO:0030534 2 0.012
regulation of rho protein signal transduction GO:0035023 2 0.012
peptidyl serine phosphorylation GO:0018105 1 0.012
nucleobase containing compound biosynthetic process GO:0034654 205 0.012
regulation of transcription dna templated GO:0006355 213 0.012
regulation of nucleic acid templated transcription GO:1903506 213 0.012
multicellular organismal macromolecule metabolic process GO:0044259 2 0.012
lipid homeostasis GO:0055088 3 0.012
Mouse
negative regulation of secretion by cell GO:1903531 2 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.012
cellular carbohydrate metabolic process GO:0044262 4 0.012
dorsal ventral pattern formation GO:0009953 125 0.012
regulation of production of molecular mediator of immune response GO:0002700 1 0.012
regulation of reactive oxygen species metabolic process GO:2000377 2 0.012
chordate embryonic development GO:0043009 271 0.012
negative regulation of metabolic process GO:0009892 86 0.012
regulation of protein polymerization GO:0032271 2 0.012
circulatory system process GO:0003013 87 0.012
cellular response to oxygen levels GO:0071453 1 0.012
striated muscle cell differentiation GO:0051146 129 0.012
cellular response to chemical stimulus GO:0070887 157 0.012
response to corticosteroid GO:0031960 1 0.012
development of primary female sexual characteristics GO:0046545 4 0.012
regulation of cell differentiation GO:0045595 142 0.012
cellular response to molecule of bacterial origin GO:0071219 3 0.012
oocyte maturation GO:0001556 4 0.012
myotube differentiation GO:0014902 45 0.012
regulation of purine nucleotide catabolic process GO:0033121 2 0.012
gland development GO:0048732 143 0.012
regulation of protein binding GO:0043393 3 0.012
extrinsic apoptotic signaling pathway GO:0097191 3 0.012
regulation of erk1 and erk2 cascade GO:0070372 4 0.012
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.012
cortical actin cytoskeleton organization GO:0030866 1 0.012
muscle organ development GO:0007517 101 0.012
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.011
response to other organism GO:0051707 97 0.011
female gonad development GO:0008585 4 0.011
carboxylic acid catabolic process GO:0046395 3 0.011
negative regulation of catabolic process GO:0009895 3 0.011
cytoskeleton dependent cytokinesis GO:0061640 3 0.011
intracellular mrna localization GO:0008298 1 0.011
organelle fusion GO:0048284 3 0.011
positive regulation of multi organism process GO:0043902 3 0.011
energy reserve metabolic process GO:0006112 2 0.011
neurological system process GO:0050877 62 0.011
amino acid transport GO:0006865 2 0.011
negative regulation of protein localization to nucleus GO:1900181 2 0.011
post embryonic organ development GO:0048569 4 0.011
secondary metabolic process GO:0019748 3 0.011
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.011
neuron development GO:0048666 262 0.011
negative regulation of intracellular transport GO:0032387 3 0.011
cellular response to light stimulus GO:0071482 4 0.011
establishment of endothelial barrier GO:0061028 3 0.011
negative regulation of defense response GO:0031348 2 0.011
embryonic organ morphogenesis GO:0048562 274 0.011
regulation of neural precursor cell proliferation GO:2000177 3 0.011
cellular response to hypoxia GO:0071456 1 0.011
regulation of mrna processing GO:0050684 3 0.011
negative regulation of dna metabolic process GO:0051053 4 0.011
vacuolar transport GO:0007034 2 0.011
cell aging GO:0007569 2 0.011
centrosome organization GO:0051297 1 0.011
nucleic acid transport GO:0050657 2 0.011
cellular protein modification process GO:0006464 100 0.011
sensory perception of pain GO:0019233 1 0.011
g1 s transition of mitotic cell cycle GO:0000082 1 0.011
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.011
cell cycle GO:0007049 93 0.011
positive regulation of leukocyte differentiation GO:1902107 1 0.011
transcription from rna polymerase ii promoter GO:0006366 80 0.011
locomotor rhythm GO:0045475 3 0.011
negative regulation of secretion GO:0051048 2 0.011
regulation of jak stat cascade GO:0046425 3 0.011
nuclear export GO:0051168 1 0.011
cell fate commitment GO:0045165 99 0.011
interspecies interaction between organisms GO:0044419 4 0.011
macromolecule biosynthetic process GO:0009059 227 0.010
fertilization GO:0009566 3 0.010
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.010
death GO:0016265 121 0.010
phagocytosis engulfment GO:0006911 1 0.010
negative regulation of sequestering of calcium ion GO:0051283 4 0.010
regulation of blood pressure GO:0008217 1 0.010
immunoglobulin mediated immune response GO:0016064 3 0.010
regulation of carbohydrate metabolic process GO:0006109 4 0.010
carbohydrate biosynthetic process GO:0016051 1 0.010
negative regulation of multi organism process GO:0043901 3 0.010
response to glucocorticoid GO:0051384 1 0.010
cytoskeleton organization GO:0007010 96 0.010
negative regulation of kinase activity GO:0033673 4 0.010
actin filament based process GO:0030029 64 0.010
muscle tissue development GO:0060537 110 0.010
signal transduction in absence of ligand GO:0038034 1 0.010
regulation of gtp catabolic process GO:0033124 2 0.010
negative regulation of cytoplasmic transport GO:1903650 2 0.010
multicellular organismal response to stress GO:0033555 2 0.010
hematopoietic or lymphoid organ development GO:0048534 191 0.010
b cell mediated immunity GO:0019724 3 0.010
cell death GO:0008219 121 0.010
regulation of cell substrate adhesion GO:0010810 1 0.010
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.010
positive regulation of muscle cell differentiation GO:0051149 1 0.010
organic acid catabolic process GO:0016054 3 0.010

ephx2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.032
disease of metabolism DOID:0014667 0 0.028
disease of cellular proliferation DOID:14566 0 0.018
cancer DOID:162 0 0.018
organ system cancer DOID:0050686 0 0.017
nervous system disease DOID:863 0 0.015
inherited metabolic disorder DOID:655 0 0.015
cardiovascular system disease DOID:1287 0 0.013
eye and adnexa disease DOID:1492 0 0.012
sensory system disease DOID:0050155 0 0.012
musculoskeletal system disease DOID:17 0 0.011
eye disease DOID:5614 0 0.010