Danio rerio

0 known processes

ptges3a

prostaglandin E synthase 3a (cytosolic)

(Aliases: cPGES-1,zgc:77131,ptges3,Tebp,zgc:65804,wu:fb98d06)

ptges3a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of metabolic process GO:0019222 359 0.504
Rat
regulation of biological quality GO:0065008 263 0.196
macromolecule biosynthetic process GO:0009059 227 0.192
Human Mouse
regulation of gene expression GO:0010468 265 0.185
Rat
mitochondrion organization GO:0007005 4 0.176
anterior posterior pattern specification GO:0009952 152 0.158
regulation of cellular metabolic process GO:0031323 320 0.150
purine nucleoside monophosphate catabolic process GO:0009128 4 0.143
signal transduction GO:0007165 455 0.143
Mouse
regulation of nucleic acid templated transcription GO:1903506 213 0.132
aging GO:0007568 2 0.132
regulation of rna biosynthetic process GO:2001141 213 0.128
nucleic acid templated transcription GO:0097659 181 0.120
locomotion GO:0040011 313 0.116
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.105
organic cyclic compound metabolic process GO:1901360 301 0.103
Human
regulation of nitrogen compound metabolic process GO:0051171 251 0.097
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.097
regulation of macromolecule metabolic process GO:0060255 317 0.096
Rat
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.093
positive regulation of biological process GO:0048518 253 0.091
Rat
positive regulation of cellular process GO:0048522 201 0.088
segmentation GO:0035282 97 0.088
cellular protein metabolic process GO:0044267 129 0.079
Human
negative regulation of cellular process GO:0048523 283 0.077
Rat
digestive tract morphogenesis GO:0048546 231 0.077
larval development GO:0002164 2 0.075
regulation of response to stimulus GO:0048583 269 0.075
regulation of protein ubiquitination GO:0031396 3 0.074
ribonucleoside monophosphate catabolic process GO:0009158 4 0.074
vasculature development GO:0001944 278 0.072
organic cyclic compound biosynthetic process GO:1901362 223 0.071
Human
nucleoside monophosphate catabolic process GO:0009125 4 0.071
gene expression GO:0010467 252 0.070
Rat
regulation of signal transduction GO:0009966 225 0.069
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.068
aromatic compound biosynthetic process GO:0019438 217 0.067
Human
regulation of rna metabolic process GO:0051252 224 0.065
modification dependent macromolecule catabolic process GO:0043632 3 0.065
organic substance biosynthetic process GO:1901576 289 0.063
Human Mouse Rat
cellular macromolecule metabolic process GO:0044260 391 0.063
Human Mouse
regulation of biosynthetic process GO:0009889 250 0.062
single organism localization GO:1902578 225 0.062
negative regulation of biological process GO:0048519 304 0.062
Rat
single organism metabolic process GO:0044710 217 0.062
Human Mouse Rat
single organism biosynthetic process GO:0044711 71 0.061
Human Mouse Rat
transcription dna templated GO:0006351 181 0.061
cellular amide metabolic process GO:0043603 4 0.060
nucleobase containing compound biosynthetic process GO:0034654 205 0.059
Human
organic acid metabolic process GO:0006082 31 0.059
Human Mouse Rat
central nervous system development GO:0007417 387 0.058
embryo development ending in birth or egg hatching GO:0009792 271 0.058
Worm
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.057
regulation of cellular amine metabolic process GO:0033238 0 0.056
heterocycle biosynthetic process GO:0018130 215 0.056
Human
cellular nitrogen compound metabolic process GO:0034641 290 0.054
Human
nucleic acid metabolic process GO:0090304 244 0.052
Human
nitrogen compound metabolic process GO:0006807 319 0.052
Human
small molecule metabolic process GO:0044281 77 0.051
Human Mouse Rat
immune system process GO:0002376 241 0.051
regulation of cellular biosynthetic process GO:0031326 245 0.050
atp catabolic process GO:0006200 4 0.049
oocyte maturation GO:0001556 4 0.049
cell surface receptor signaling pathway GO:0007166 325 0.049
nucleobase containing compound metabolic process GO:0006139 274 0.048
Human
regulation of signaling GO:0023051 235 0.048
regulation of protein complex assembly GO:0043254 3 0.047
hemopoiesis GO:0030097 183 0.047
dicarboxylic acid metabolic process GO:0043648 1 0.046
regulation of cell communication GO:0010646 232 0.045
generation of neurons GO:0048699 385 0.045
regionalization GO:0003002 274 0.044
cellular nitrogen compound biosynthetic process GO:0044271 218 0.044
Human
regulation of calcium ion transport GO:0051924 2 0.044
cellular response to external stimulus GO:0071496 2 0.043
blood vessel development GO:0001568 246 0.043
positive regulation of cellular component biogenesis GO:0044089 3 0.042
positive regulation of catabolic process GO:0009896 4 0.042
response to external stimulus GO:0009605 264 0.042
microtubule cytoskeleton organization GO:0000226 33 0.042
localization of cell GO:0051674 244 0.042
antimicrobial humoral response GO:0019730 2 0.040
cellular component biogenesis GO:0044085 178 0.039
cellular component assembly GO:0022607 170 0.039
single organism organelle organization GO:1902589 199 0.039
cytoskeleton organization GO:0007010 96 0.038
regulation of primary metabolic process GO:0080090 311 0.038
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.037
regulation of nucleotide catabolic process GO:0030811 2 0.037
regulation of transcription dna templated GO:0006355 213 0.037
chordate embryonic development GO:0043009 271 0.037
cellular protein modification process GO:0006464 100 0.037
digestive system development GO:0055123 289 0.036
cation transport GO:0006812 81 0.036
mitochondrial transport GO:0006839 2 0.036
modification dependent protein catabolic process GO:0019941 3 0.035
phosphorus metabolic process GO:0006793 109 0.035
centrosome organization GO:0051297 1 0.035
regulation of macromolecule biosynthetic process GO:0010556 225 0.034
regulation of metal ion transport GO:0010959 4 0.034
microtubule organizing center organization GO:0031023 1 0.034
protein metabolic process GO:0019538 183 0.034
Human
positive regulation of transport GO:0051050 2 0.034
rhombomere 6 development GO:0021572 4 0.034
peptide metabolic process GO:0006518 1 0.034
single organism transport GO:0044765 206 0.034
circadian sleep wake cycle GO:0042745 2 0.033
negative regulation of signaling GO:0023057 96 0.033
hematopoietic or lymphoid organ development GO:0048534 191 0.032
regulation of erk1 and erk2 cascade GO:0070372 4 0.031
macromolecular complex subunit organization GO:0043933 74 0.031
negative regulation of protein phosphorylation GO:0001933 4 0.031
amine metabolic process GO:0009308 2 0.030
establishment of localization GO:0051234 244 0.030
glucose homeostasis GO:0042593 1 0.030
odontogenesis of dentin containing tooth GO:0042475 1 0.030
intracellular signal transduction GO:0035556 85 0.030
cellular component movement GO:0006928 335 0.029
cellular amine metabolic process GO:0044106 2 0.029
response to topologically incorrect protein GO:0035966 2 0.029
organonitrogen compound metabolic process GO:1901564 74 0.029
positive regulation of protein complex assembly GO:0031334 2 0.029
regulation of multicellular organismal process GO:0051239 277 0.029
cilium morphogenesis GO:0060271 85 0.028
morphogenesis of an epithelium GO:0002009 333 0.028
positive regulation of cellular catabolic process GO:0031331 3 0.028
microtubule based process GO:0007017 60 0.028
rna metabolic process GO:0016070 219 0.028
erk1 and erk2 cascade GO:0070371 4 0.027
cellular response to chemical stimulus GO:0070887 157 0.027
transport GO:0006810 220 0.027
regulation of production of molecular mediator of immune response GO:0002700 1 0.027
head development GO:0060322 303 0.027
cytoskeleton dependent cytokinesis GO:0061640 3 0.027
mononuclear cell proliferation GO:0032943 1 0.027
biosynthetic process GO:0009058 294 0.026
Human Mouse Rat
transcription from rna polymerase ii promoter GO:0006366 80 0.026
rostrocaudal neural tube patterning GO:0021903 29 0.026
centrosome cycle GO:0007098 1 0.026
ubiquitin dependent protein catabolic process GO:0006511 3 0.026
regulation of response to biotic stimulus GO:0002831 2 0.026
negative regulation of cellular metabolic process GO:0031324 77 0.025
neurotransmitter transport GO:0006836 2 0.025
regulation of reproductive process GO:2000241 4 0.025
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.025
mitotic dna damage checkpoint GO:0044773 4 0.025
negative regulation of protein kinase activity GO:0006469 4 0.025
regulation of reactive oxygen species metabolic process GO:2000377 2 0.025
protein stabilization GO:0050821 2 0.025
heterocycle metabolic process GO:0046483 290 0.025
Human
embryonic pattern specification GO:0009880 44 0.025
circadian sleep wake cycle sleep GO:0050802 1 0.025
negative regulation of response to stimulus GO:0048585 104 0.024
pancreas development GO:0031016 84 0.024
regulation of cell activation GO:0050865 1 0.024
regulation of sodium ion transport GO:0002028 2 0.024
cellular ketone metabolic process GO:0042180 11 0.024
somitogenesis GO:0001756 87 0.023
immune system development GO:0002520 191 0.023
behavior GO:0007610 74 0.023
negative regulation of cell communication GO:0010648 96 0.023
rna biosynthetic process GO:0032774 181 0.023
regulation of carbohydrate metabolic process GO:0006109 4 0.023
regulation of cell shape GO:0008360 1 0.023
regulation of cellular amino acid metabolic process GO:0006521 0 0.023
cellular amino acid metabolic process GO:0006520 7 0.023
carboxylic acid metabolic process GO:0019752 22 0.023
Human Mouse Rat
purine ribonucleotide metabolic process GO:0009150 27 0.023
regulation of cellular protein catabolic process GO:1903362 1 0.023
regulation of cellular ketone metabolic process GO:0010565 7 0.023
regulation of localization GO:0032879 104 0.022
response to organic substance GO:0010033 153 0.022
regulation of nucleoside metabolic process GO:0009118 2 0.022
establishment of protein localization to organelle GO:0072594 4 0.022
cell death GO:0008219 121 0.022
Rat
adult behavior GO:0030534 2 0.022
protein modification process GO:0036211 100 0.022
neural tube patterning GO:0021532 33 0.022
intracellular estrogen receptor signaling pathway GO:0030520 3 0.022
b cell activation GO:0042113 2 0.022
regulation of purine nucleotide catabolic process GO:0033121 2 0.021
regulation of anatomical structure morphogenesis GO:0022603 130 0.021
cellular response to topologically incorrect protein GO:0035967 2 0.021
carbohydrate homeostasis GO:0033500 1 0.021
cell motility GO:0048870 244 0.021
positive regulation of transcription dna templated GO:0045893 57 0.021
ion transport GO:0006811 114 0.021
brain development GO:0007420 293 0.021
positive regulation of nucleotide catabolic process GO:0030813 1 0.021
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.021
otolith development GO:0048840 32 0.020
tube morphogenesis GO:0035239 349 0.020
negative regulation of signal transduction GO:0009968 94 0.020
amide biosynthetic process GO:0043604 1 0.020
regulation of neurotransmitter secretion GO:0046928 1 0.020
regulation of microtubule cytoskeleton organization GO:0070507 3 0.020
cellular response to extracellular stimulus GO:0031668 2 0.020
protein secretion GO:0009306 1 0.020
positive regulation of biosynthetic process GO:0009891 68 0.020
response to light stimulus GO:0009416 46 0.020
regulation of intracellular protein transport GO:0033157 3 0.020
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.020
autophagy GO:0006914 4 0.019
organonitrogen compound biosynthetic process GO:1901566 47 0.019
leukocyte proliferation GO:0070661 1 0.019
response to growth factor GO:0070848 39 0.019
peptide transport GO:0015833 1 0.019
proteasomal protein catabolic process GO:0010498 2 0.019
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.019
alpha amino acid metabolic process GO:1901605 3 0.019
macromolecule modification GO:0043412 111 0.019
enzyme linked receptor protein signaling pathway GO:0007167 106 0.019
cellular response to endogenous stimulus GO:0071495 68 0.019
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.019
protein polymerization GO:0051258 4 0.018
cell migration GO:0016477 237 0.018
response to stress GO:0006950 263 0.018
cellular protein catabolic process GO:0044257 4 0.018
embryonic organ development GO:0048568 381 0.018
regulation of cytoplasmic transport GO:1903649 4 0.018
kupffer s vesicle development GO:0070121 50 0.018
cellular macromolecule biosynthetic process GO:0034645 224 0.018
Human Mouse
cellular transition metal ion homeostasis GO:0046916 3 0.018
negative regulation of protein transport GO:0051224 3 0.018
phosphorylation GO:0016310 69 0.018
response to monosaccharide GO:0034284 3 0.018
female sex differentiation GO:0046660 4 0.018
positive regulation of secretion GO:0051047 1 0.017
regulation of nucleocytoplasmic transport GO:0046822 2 0.017
positive regulation of metabolic process GO:0009893 108 0.017
Rat
positive regulation of cytoskeleton organization GO:0051495 3 0.017
developmental programmed cell death GO:0010623 4 0.017
positive regulation of response to stimulus GO:0048584 80 0.017
negative regulation of leukocyte differentiation GO:1902106 1 0.017
stem cell proliferation GO:0072089 4 0.017
calcium mediated signaling GO:0019722 2 0.017
respiratory electron transport chain GO:0022904 2 0.017
myeloid cell differentiation GO:0030099 86 0.017
erythrocyte differentiation GO:0030218 54 0.017
connective tissue development GO:0061448 99 0.017
hormone transport GO:0009914 2 0.017
cell part morphogenesis GO:0032990 246 0.017
organelle organization GO:0006996 227 0.017
negative regulation of kinase activity GO:0033673 4 0.017
gastrulation GO:0007369 208 0.017
somite development GO:0061053 96 0.017
cellular macromolecular complex assembly GO:0034622 24 0.017
regulation of stem cell proliferation GO:0072091 2 0.017
nuclear import GO:0051170 3 0.017
skeletal muscle tissue development GO:0007519 67 0.017
cellular response to starvation GO:0009267 1 0.017
positive regulation of immune effector process GO:0002699 3 0.017
meiosis i GO:0007127 1 0.016
single organism nuclear import GO:1902593 3 0.016
semicircular canal development GO:0060872 24 0.016
cellular response to oxygen levels GO:0071453 1 0.016
transition metal ion transport GO:0000041 6 0.016
reactive oxygen species metabolic process GO:0072593 6 0.016
cellular response to nutrient levels GO:0031669 2 0.016
erythrocyte homeostasis GO:0034101 55 0.016
leukocyte differentiation GO:0002521 25 0.016
neurological system process GO:0050877 62 0.016
Rat
skeletal muscle organ development GO:0060538 78 0.016
cellular biosynthetic process GO:0044249 286 0.016
Human Mouse Rat
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.016
inner ear development GO:0048839 126 0.016
production of molecular mediator of immune response GO:0002440 2 0.016
cellular component morphogenesis GO:0032989 336 0.016
regulation of protein transport GO:0051223 3 0.016
fatty acid biosynthetic process GO:0006633 4 0.016
Human Mouse Rat
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.016
convergent extension involved in organogenesis GO:0060029 10 0.016
positive regulation of multi organism process GO:0043902 3 0.015
response to endogenous stimulus GO:0009719 83 0.015
b cell differentiation GO:0030183 1 0.015
negative regulation of mapk cascade GO:0043409 4 0.015
negative regulation of myeloid cell differentiation GO:0045638 1 0.015
regulation of hormone secretion GO:0046883 2 0.015
regulation of multicellular organism growth GO:0040014 4 0.015
chemosensory behavior GO:0007635 1 0.015
positive regulation of cellular amine metabolic process GO:0033240 0 0.015
positive regulation of map kinase activity GO:0043406 3 0.015
mitotic dna integrity checkpoint GO:0044774 4 0.015
ear development GO:0043583 127 0.015
astrocyte differentiation GO:0048708 1 0.015
blood vessel morphogenesis GO:0048514 216 0.015
hepaticobiliary system development GO:0061008 98 0.015
cellular response to growth factor stimulus GO:0071363 39 0.015
g protein coupled receptor signaling pathway GO:0007186 74 0.015
response to unfolded protein GO:0006986 2 0.015
regulation of hormone levels GO:0010817 21 0.015
exocrine pancreas development GO:0031017 28 0.015
cellular response to light stimulus GO:0071482 4 0.014
positive regulation of nucleoside metabolic process GO:0045979 1 0.014
cytokinesis GO:0000910 3 0.014
regulation of establishment of protein localization GO:0070201 4 0.014
developmental growth GO:0048589 166 0.014
regulation of cellular response to growth factor stimulus GO:0090287 35 0.014
intracellular steroid hormone receptor signaling pathway GO:0030518 5 0.014
Mouse
convergent extension GO:0060026 118 0.014
mitotic cell cycle process GO:1903047 48 0.014
nucleocytoplasmic transport GO:0006913 4 0.014
response to chemical GO:0042221 320 0.014
androgen metabolic process GO:0008209 2 0.014
nuclear transport GO:0051169 4 0.014
defense response to fungus GO:0050832 2 0.014
regulation of protein metabolic process GO:0051246 56 0.014
lymphocyte proliferation GO:0046651 1 0.014
peptidyl serine modification GO:0018209 2 0.014
synaptic growth at neuromuscular junction GO:0051124 2 0.014
positive regulation of nucleic acid templated transcription GO:1903508 57 0.014
olfactory lobe development GO:0021988 4 0.014
hormone secretion GO:0046879 2 0.014
regulation of cytokine production GO:0001817 3 0.014
positive regulation of rna biosynthetic process GO:1902680 57 0.014
protein targeting to nucleus GO:0044744 3 0.014
cellular response to radiation GO:0071478 4 0.013
cellular response to hypoxia GO:0071456 1 0.013
regulation of developmental process GO:0050793 247 0.013
cell projection morphogenesis GO:0048858 244 0.013
toll like receptor signaling pathway GO:0002224 4 0.013
transmembrane transport GO:0055085 120 0.013
developmental maturation GO:0021700 34 0.013
regulation of circadian sleep wake cycle GO:0042749 1 0.013
multi organism process GO:0051704 134 0.013
positive regulation of translation GO:0045727 1 0.013
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 9 0.013
positive regulation of secretion by cell GO:1903532 1 0.013
regulation of tube size GO:0035150 2 0.013
regulation of molecular function GO:0065009 70 0.013
positive regulation of cellular metabolic process GO:0031325 94 0.013
regulation of cellular protein metabolic process GO:0032268 52 0.013
circadian sleep wake cycle process GO:0022410 2 0.013
positive regulation of defense response to virus by host GO:0002230 0 0.013
macromolecular complex assembly GO:0065003 35 0.013
cellular component assembly involved in morphogenesis GO:0010927 107 0.013
regulation of tissue remodeling GO:0034103 2 0.013
reactive oxygen species biosynthetic process GO:1903409 1 0.012
cell projection organization GO:0030030 284 0.012
regulation of carbohydrate biosynthetic process GO:0043255 1 0.012
midbrain hindbrain boundary development GO:0030917 23 0.012
meiotic nuclear division GO:0007126 4 0.012
eye development GO:0001654 277 0.012
negative regulation of metabolic process GO:0009892 86 0.012
cellular response to unfolded protein GO:0034620 2 0.012
cell cycle GO:0007049 93 0.012
mitotic cytokinesis GO:0000281 3 0.012
cellular response to decreased oxygen levels GO:0036294 1 0.012
response to hexose GO:0009746 3 0.012
cell morphogenesis GO:0000902 289 0.012
regulation of cell substrate adhesion GO:0010810 1 0.012
actin polymerization or depolymerization GO:0008154 2 0.012
neuron development GO:0048666 262 0.012
mrna stabilization GO:0048255 4 0.012
phosphate containing compound metabolic process GO:0006796 108 0.012
intracellular receptor signaling pathway GO:0030522 30 0.012
Mouse
response to fungus GO:0009620 25 0.012
specification of axis polarity GO:0065001 4 0.012
positive regulation of muscle organ development GO:0048636 1 0.012
tissue remodeling GO:0048771 4 0.012
maintenance of location GO:0051235 4 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.012
negative regulation of protein import into nucleus GO:0042308 2 0.012
lateral line development GO:0048882 66 0.012
positive regulation of gene expression GO:0010628 71 0.011
Rat
regulation of behavior GO:0050795 24 0.011
regulation of protein targeting GO:1903533 2 0.011
protein import GO:0017038 3 0.011
hormone biosynthetic process GO:0042446 3 0.011
homeostatic process GO:0042592 142 0.011
negative regulation of macromolecule metabolic process GO:0010605 76 0.011
mitochondrion morphogenesis GO:0070584 2 0.011
apoptotic process involved in morphogenesis GO:0060561 2 0.011
camera type eye development GO:0043010 222 0.011
regulation of blood vessel size GO:0050880 2 0.011
divalent inorganic cation transport GO:0072511 21 0.011
camera type eye morphogenesis GO:0048593 108 0.011
ribonucleotide metabolic process GO:0009259 27 0.011
pronuclear migration GO:0035046 1 0.011
er nucleus signaling pathway GO:0006984 2 0.011
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.011
regulation of protein catabolic process GO:0042176 1 0.011
response to uv GO:0009411 3 0.011
ovulation cycle GO:0042698 2 0.011
organic substance transport GO:0071702 58 0.011
reproductive process GO:0022414 40 0.011
developmental growth involved in morphogenesis GO:0060560 86 0.011
sphingolipid biosynthetic process GO:0030148 2 0.011
organelle assembly GO:0070925 110 0.011
response to alkaloid GO:0043279 2 0.011
regulation of response to extracellular stimulus GO:0032104 1 0.011
protein complex biogenesis GO:0070271 30 0.011
regulation of skeletal muscle tissue development GO:0048641 4 0.010
mesenchymal cell proliferation GO:0010463 1 0.010
telomere organization GO:0032200 1 0.010
regulation of bone remodeling GO:0046850 2 0.010
detection of external stimulus GO:0009581 24 0.010
regulation of protein import into nucleus GO:0042306 2 0.010
negative regulation of i kappab kinase nf kappab signaling GO:0043124 1 0.010
cell migration involved in heart formation GO:0060974 10 0.010
nucleotide biosynthetic process GO:0009165 21 0.010
hindbrain development GO:0030902 91 0.010
small molecule catabolic process GO:0044282 3 0.010
metal ion transport GO:0030001 58 0.010
sensory organ morphogenesis GO:0090596 200 0.010
actin filament polymerization GO:0030041 2 0.010
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.010
angiogenesis GO:0001525 158 0.010
response to abiotic stimulus GO:0009628 122 0.010
lipid metabolic process GO:0006629 52 0.010
Human Mouse Rat
regulation of protein localization to nucleus GO:1900180 2 0.010
digestive tract development GO:0048565 265 0.010

ptges3a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.028
inherited metabolic disorder DOID:655 0 0.023
disease of anatomical entity DOID:7 0 0.019
musculoskeletal system disease DOID:17 0 0.014
muscular disease DOID:0080000 0 0.013
disease of cellular proliferation DOID:14566 0 0.011
heart disease DOID:114 0 0.010
cardiovascular system disease DOID:1287 0 0.010