Danio rerio

0 known processes

zgc:92022

zgc:92022

zgc:92022 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.074
aging GO:0007568 2 0.058
organelle fusion GO:0048284 3 0.054
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.046
phagocytosis GO:0006909 3 0.043
autophagy GO:0006914 4 0.043
endosomal transport GO:0016197 2 0.041
positive regulation of transport GO:0051050 2 0.041
membrane fusion GO:0061025 2 0.040
single organism membrane fusion GO:0044801 2 0.040
guanosine containing compound metabolic process GO:1901068 4 0.037
gtp metabolic process GO:0046039 4 0.037
modification dependent protein catabolic process GO:0019941 3 0.036
guanosine containing compound catabolic process GO:1901069 2 0.035
establishment of protein localization to organelle GO:0072594 4 0.033
cellular protein catabolic process GO:0044257 4 0.032
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.032
mitochondrion organization GO:0007005 4 0.031
multicellular organism growth GO:0035264 4 0.031
signal transduction GO:0007165 455 0.030
establishment of localization GO:0051234 244 0.030
cellular nitrogen compound metabolic process GO:0034641 290 0.030
transport GO:0006810 220 0.030
cellular response to nutrient levels GO:0031669 2 0.030
regulation of multicellular organism growth GO:0040014 4 0.030
regulation of protein complex assembly GO:0043254 3 0.030
maintenance of location GO:0051235 4 0.029
nitrogen compound metabolic process GO:0006807 319 0.029
modification dependent macromolecule catabolic process GO:0043632 3 0.029
single organism metabolic process GO:0044710 217 0.029
gtp catabolic process GO:0006184 2 0.029
positive regulation of catabolic process GO:0009896 4 0.029
positive regulation of cellular catabolic process GO:0031331 3 0.028
meiotic nuclear division GO:0007126 4 0.028
proteasomal protein catabolic process GO:0010498 2 0.027
cellular macromolecule metabolic process GO:0044260 391 0.027
single organism localization GO:1902578 225 0.027
regulation of purine nucleotide catabolic process GO:0033121 2 0.027
cellular response to starvation GO:0009267 1 0.026
single organism organelle organization GO:1902589 199 0.026
regulation of nucleotide catabolic process GO:0030811 2 0.026
cellular response to external stimulus GO:0071496 2 0.026
organic cyclic compound metabolic process GO:1901360 301 0.025
regulation of synaptic plasticity GO:0048167 1 0.025
cell surface receptor signaling pathway GO:0007166 325 0.025
ubiquitin dependent protein catabolic process GO:0006511 3 0.025
amine metabolic process GO:0009308 2 0.025
cellular aromatic compound metabolic process GO:0006725 295 0.025
regulation of nucleoside metabolic process GO:0009118 2 0.025
regulation of cytokine production GO:0001817 3 0.025
cellular response to extracellular stimulus GO:0031668 2 0.024
nucleobase containing compound metabolic process GO:0006139 274 0.024
generation of neurons GO:0048699 385 0.024
response to external stimulus GO:0009605 264 0.024
positive regulation of cell cycle GO:0045787 3 0.024
lipid storage GO:0019915 1 0.024
regulation of cell communication GO:0010646 232 0.024
cellular component morphogenesis GO:0032989 336 0.024
organonitrogen compound metabolic process GO:1901564 74 0.024
heterocycle metabolic process GO:0046483 290 0.024
regulation of metabolic process GO:0019222 359 0.024
neuron differentiation GO:0030182 353 0.023
ribonucleoside monophosphate catabolic process GO:0009158 4 0.023
cell projection organization GO:0030030 284 0.023
nuclear import GO:0051170 3 0.023
small molecule metabolic process GO:0044281 77 0.023
cellular amine metabolic process GO:0044106 2 0.023
response to chemical GO:0042221 320 0.023
rna localization GO:0006403 4 0.023
regulation of signaling GO:0023051 235 0.023
rna modification GO:0009451 2 0.023
regulation of response to stimulus GO:0048583 269 0.022
single organism transport GO:0044765 206 0.022
positive regulation of cellular component biogenesis GO:0044089 3 0.022
response to stress GO:0006950 263 0.022
organelle organization GO:0006996 227 0.022
negative regulation of protein phosphorylation GO:0001933 4 0.022
synaptic vesicle transport GO:0048489 1 0.022
embryonic organ development GO:0048568 381 0.022
nucleic acid metabolic process GO:0090304 244 0.021
regulation of binding GO:0051098 3 0.021
skeletal system development GO:0001501 181 0.021
cell projection morphogenesis GO:0048858 244 0.021
protein import GO:0017038 3 0.021
regulation of cellular metabolic process GO:0031323 320 0.021
atp catabolic process GO:0006200 4 0.021
response to drug GO:0042493 3 0.020
regulation of protein transport GO:0051223 3 0.020
cognition GO:0050890 1 0.020
exocytosis GO:0006887 1 0.020
positive regulation of secretion GO:0051047 1 0.020
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.020
cell part morphogenesis GO:0032990 246 0.020
negative regulation of cellular process GO:0048523 283 0.020
regulation of cellular amine metabolic process GO:0033238 0 0.020
synaptic growth at neuromuscular junction GO:0051124 2 0.020
protein localization to nucleus GO:0034504 3 0.020
cellular biosynthetic process GO:0044249 286 0.020
carboxylic acid metabolic process GO:0019752 22 0.020
extrinsic apoptotic signaling pathway GO:0097191 3 0.020
immune system development GO:0002520 191 0.019
cellular response to xenobiotic stimulus GO:0071466 35 0.019
regulation of nitrogen compound metabolic process GO:0051171 251 0.019
regulation of biological quality GO:0065008 263 0.019
tissue remodeling GO:0048771 4 0.019
organic substance biosynthetic process GO:1901576 289 0.019
neurotransmitter transport GO:0006836 2 0.019
embryo development ending in birth or egg hatching GO:0009792 271 0.019
neurotransmitter secretion GO:0007269 2 0.019
rna metabolic process GO:0016070 219 0.019
single organism nuclear import GO:1902593 3 0.019
regulation of metal ion transport GO:0010959 4 0.019
oxoacid metabolic process GO:0043436 31 0.018
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.018
regulation of cytoplasmic transport GO:1903649 4 0.018
nucleocytoplasmic transport GO:0006913 4 0.018
regulation of biosynthetic process GO:0009889 250 0.018
protein targeting to nucleus GO:0044744 3 0.018
response to topologically incorrect protein GO:0035966 2 0.018
purine nucleoside monophosphate catabolic process GO:0009128 4 0.018
positive regulation of nucleotide catabolic process GO:0030813 1 0.018
organic acid metabolic process GO:0006082 31 0.018
regulation of reproductive process GO:2000241 4 0.018
stem cell proliferation GO:0072089 4 0.018
gene expression GO:0010467 252 0.018
cellular amide metabolic process GO:0043603 4 0.018
cellular component disassembly GO:0022411 1 0.018
cell morphogenesis GO:0000902 289 0.018
regulation of intracellular protein transport GO:0033157 3 0.018
immune system process GO:0002376 241 0.018
positive regulation of gtpase activity GO:0043547 1 0.018
negative regulation of biological process GO:0048519 304 0.017
cellular response to topologically incorrect protein GO:0035967 2 0.017
synaptic vesicle localization GO:0097479 1 0.017
i kappab kinase nf kappab signaling GO:0007249 4 0.017
protein metabolic process GO:0019538 183 0.017
organic cyclic compound biosynthetic process GO:1901362 223 0.017
regulation of protein targeting GO:1903533 2 0.017
peptide transport GO:0015833 1 0.017
regulation of protein localization to nucleus GO:1900180 2 0.017
peptidyl serine phosphorylation GO:0018105 1 0.017
hemopoiesis GO:0030097 183 0.017
protein localization to plasma membrane GO:0072659 1 0.017
meiotic cell cycle process GO:1903046 3 0.017
nucleobase containing compound biosynthetic process GO:0034654 205 0.017
cellular amino acid metabolic process GO:0006520 7 0.017
regulation of gtp catabolic process GO:0033124 2 0.017
protein acetylation GO:0006473 2 0.017
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.016
regulation of signal transduction GO:0009966 225 0.016
regulation of dendrite development GO:0050773 3 0.016
biosynthetic process GO:0009058 294 0.016
regulation of cellular ketone metabolic process GO:0010565 7 0.016
regulation of cell activation GO:0050865 1 0.016
regulation of gtpase activity GO:0043087 2 0.016
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.016
transcription dna templated GO:0006351 181 0.016
cellular response to chemical stimulus GO:0070887 157 0.016
positive regulation of stress activated mapk cascade GO:0032874 3 0.016
regulation of cellular biosynthetic process GO:0031326 245 0.016
meiotic chromosome segregation GO:0045132 3 0.016
sensory organ development GO:0007423 393 0.016
nuclear transport GO:0051169 4 0.016
golgi vesicle transport GO:0048193 3 0.016
organelle assembly GO:0070925 110 0.016
alcohol biosynthetic process GO:0046165 2 0.016
stem cell maintenance GO:0019827 4 0.016
nucleoside monophosphate catabolic process GO:0009125 4 0.016
macroautophagy GO:0016236 1 0.016
protein polyubiquitination GO:0000209 4 0.016
macromolecule modification GO:0043412 111 0.016
chordate embryonic development GO:0043009 271 0.016
cellular response to radiation GO:0071478 4 0.016
regulation of sequestering of calcium ion GO:0051282 4 0.016
compound eye development GO:0048749 2 0.016
regulation of establishment of protein localization GO:0070201 4 0.016
negative regulation of sequestering of calcium ion GO:0051283 4 0.016
neuron development GO:0048666 262 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
negative regulation of protein kinase activity GO:0006469 4 0.015
regulation of nucleocytoplasmic transport GO:0046822 2 0.015
morphogenesis of an epithelium GO:0002009 333 0.015
adult behavior GO:0030534 2 0.015
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.015
regulation of protein catabolic process GO:0042176 1 0.015
regulation of stem cell proliferation GO:0072091 2 0.015
positive regulation of protein complex assembly GO:0031334 2 0.015
positive regulation of gtp catabolic process GO:0033126 1 0.015
cilium organization GO:0044782 71 0.015
regulation of synapse organization GO:0050807 3 0.015
regulation of cell shape GO:0008360 1 0.015
cellular component assembly GO:0022607 170 0.015
cytokinesis GO:0000910 3 0.015
regulation of ion transmembrane transporter activity GO:0032412 2 0.015
response to carbohydrate GO:0009743 3 0.015
negative regulation of kinase activity GO:0033673 4 0.015
negative regulation of mapk cascade GO:0043409 4 0.015
regulation of epithelial cell proliferation GO:0050678 3 0.015
positive regulation of nucleoside metabolic process GO:0045979 1 0.015
skeletal system morphogenesis GO:0048705 102 0.015
regulation of synapse assembly GO:0051963 3 0.015
response to glucose GO:0009749 3 0.015
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.015
regulation of primary metabolic process GO:0080090 311 0.014
er nucleus signaling pathway GO:0006984 2 0.014
regulation of dendrite morphogenesis GO:0048814 3 0.014
cellular component biogenesis GO:0044085 178 0.014
peptidyl lysine acetylation GO:0018394 2 0.014
positive regulation of cellular process GO:0048522 201 0.014
protein secretion GO:0009306 1 0.014
positive regulation of biological process GO:0048518 253 0.014
sequestering of calcium ion GO:0051208 3 0.014
peptide metabolic process GO:0006518 1 0.014
regulation of neuronal synaptic plasticity GO:0048168 1 0.014
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.014
cellular component movement GO:0006928 335 0.014
secondary metabolic process GO:0019748 3 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.014
growth GO:0040007 174 0.014
cellular component assembly involved in morphogenesis GO:0010927 107 0.014
locomotion GO:0040011 313 0.014
cell substrate adhesion GO:0031589 4 0.014
tube morphogenesis GO:0035239 349 0.014
central nervous system development GO:0007417 387 0.014
regulation of meiotic cell cycle GO:0051445 1 0.014
peptidyl serine modification GO:0018209 2 0.014
cellular response to biotic stimulus GO:0071216 3 0.014
regulation of multicellular organismal process GO:0051239 277 0.014
regulation of transporter activity GO:0032409 2 0.014
small molecule catabolic process GO:0044282 3 0.014
adherens junction organization GO:0034332 4 0.013
regulation of macromolecule biosynthetic process GO:0010556 225 0.013
positive regulation of cell activation GO:0050867 1 0.013
regulation of neural precursor cell proliferation GO:2000177 3 0.013
regulation of calcium ion transport GO:0051924 2 0.013
internal protein amino acid acetylation GO:0006475 2 0.013
aromatic compound biosynthetic process GO:0019438 217 0.013
response to hexose GO:0009746 3 0.013
macromolecular complex disassembly GO:0032984 1 0.013
xenobiotic metabolic process GO:0006805 4 0.013
post golgi vesicle mediated transport GO:0006892 1 0.013
centrosome organization GO:0051297 1 0.013
internal peptidyl lysine acetylation GO:0018393 2 0.013
cellular protein modification process GO:0006464 100 0.013
phagocytosis engulfment GO:0006911 1 0.013
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.013
neuroblast proliferation GO:0007405 2 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.013
gastrulation GO:0007369 208 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
interspecies interaction between organisms GO:0044419 4 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.013
digestive tract morphogenesis GO:0048546 231 0.013
nucleic acid templated transcription GO:0097659 181 0.013
muscle cell differentiation GO:0042692 139 0.013
negative regulation of cytokine production GO:0001818 1 0.013
organic acid catabolic process GO:0016054 3 0.013
positive regulation of secretion by cell GO:1903532 1 0.013
rna transport GO:0050658 2 0.013
neuron projection development GO:0031175 180 0.013
spermatid development GO:0007286 2 0.013
primary neural tube formation GO:0014020 1 0.013
cellular nitrogen compound biosynthetic process GO:0044271 218 0.013
regulation of gene expression GO:0010468 265 0.013
response to monosaccharide GO:0034284 3 0.013
positive regulation of apoptotic signaling pathway GO:2001235 1 0.013
cilium morphogenesis GO:0060271 85 0.013
cellular response to light stimulus GO:0071482 4 0.013
protein complex disassembly GO:0043241 1 0.013
cellular macromolecule biosynthetic process GO:0034645 224 0.013
actin polymerization or depolymerization GO:0008154 2 0.013
cellular protein metabolic process GO:0044267 129 0.013
neuron neuron synaptic transmission GO:0007270 1 0.013
chemosensory behavior GO:0007635 1 0.013
lateral inhibition GO:0046331 1 0.013
sequestering of metal ion GO:0051238 3 0.012
macromolecule biosynthetic process GO:0009059 227 0.012
membrane invagination GO:0010324 1 0.012
negative regulation of signaling GO:0023057 96 0.012
neuromuscular synaptic transmission GO:0007274 2 0.012
regulation of erk1 and erk2 cascade GO:0070372 4 0.012
establishment of localization in cell GO:0051649 77 0.012
viral process GO:0016032 1 0.012
system process GO:0003008 185 0.012
muscle structure development GO:0061061 196 0.012
axon development GO:0061564 166 0.012
digestive system development GO:0055123 289 0.012
hematopoietic or lymphoid organ development GO:0048534 191 0.012
fatty acid biosynthetic process GO:0006633 4 0.012
leukocyte proliferation GO:0070661 1 0.012
vasculature development GO:0001944 278 0.012
cellular response to lipopolysaccharide GO:0071222 3 0.012
regulation of macromolecule metabolic process GO:0060255 317 0.012
nucleic acid transport GO:0050657 2 0.012
cellular response to unfolded protein GO:0034620 2 0.012
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.012
response to alkaloid GO:0043279 2 0.012
hormone secretion GO:0046879 2 0.012
b cell activation GO:0042113 2 0.012
negative regulation of protein complex assembly GO:0031333 1 0.012
phosphate containing compound metabolic process GO:0006796 108 0.012
regulation of rna metabolic process GO:0051252 224 0.012
multi organism cellular process GO:0044764 2 0.012
tube closure GO:0060606 1 0.012
developmental growth GO:0048589 166 0.012
locomotor rhythm GO:0045475 3 0.012
carbohydrate homeostasis GO:0033500 1 0.012
neuron projection morphogenesis GO:0048812 161 0.012
rna biosynthetic process GO:0032774 181 0.012
eye development GO:0001654 277 0.012
regulation of circadian rhythm GO:0042752 4 0.012
regulation of neurotransmitter transport GO:0051588 1 0.012
embryonic skeletal system development GO:0048706 97 0.012
positive regulation of cytokine production GO:0001819 2 0.012
cell substrate junction assembly GO:0007044 2 0.012
cell migration GO:0016477 237 0.011
negative regulation of intracellular protein transport GO:0090317 3 0.011
response to uv GO:0009411 3 0.011
cellular lipid catabolic process GO:0044242 3 0.011
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.011
protein import into nucleus GO:0006606 3 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.011
regulation of nucleic acid templated transcription GO:1903506 213 0.011
negative regulation of catabolic process GO:0009895 3 0.011
lipid catabolic process GO:0016042 4 0.011
endoplasmic reticulum unfolded protein response GO:0030968 2 0.011
regulation of transmembrane transporter activity GO:0022898 2 0.011
regulation of multicellular organismal development GO:2000026 223 0.011
antimicrobial humoral response GO:0019730 2 0.011
cellular ketone metabolic process GO:0042180 11 0.011
microtubule based movement GO:0007018 33 0.011
response to unfolded protein GO:0006986 2 0.011
homeostatic process GO:0042592 142 0.011
positive regulation of immune effector process GO:0002699 3 0.011
erk1 and erk2 cascade GO:0070371 4 0.011
cell morphogenesis involved in differentiation GO:0000904 195 0.011
negative regulation of reproductive process GO:2000242 3 0.011
positive regulation of jnk cascade GO:0046330 3 0.011
protein acylation GO:0043543 3 0.011
spermatid differentiation GO:0048515 2 0.011
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.011
digestive tract development GO:0048565 265 0.011
regulation of autophagy GO:0010506 3 0.011
regulation of rna biosynthetic process GO:2001141 213 0.011
cellular response to organic substance GO:0071310 105 0.011
regulation of protein ubiquitination GO:0031396 3 0.011
cellular localization GO:0051641 97 0.011
mitochondrial transport GO:0006839 2 0.011
regulation of transcription dna templated GO:0006355 213 0.011
negative regulation of epithelial cell proliferation GO:0050680 1 0.011
alpha amino acid metabolic process GO:1901605 3 0.011
negative regulation of signal transduction GO:0009968 94 0.011
heterocycle biosynthetic process GO:0018130 215 0.011
phosphorus metabolic process GO:0006793 109 0.010
axonogenesis GO:0007409 152 0.010
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.010
positive regulation of cytoskeleton organization GO:0051495 3 0.010
establishment of synaptic vesicle localization GO:0097480 1 0.010
cell death GO:0008219 121 0.010
negative regulation of multi organism process GO:0043901 3 0.010
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.010
regulation of microtubule cytoskeleton organization GO:0070507 3 0.010
positive regulation of cell adhesion GO:0045785 1 0.010
actin filament polymerization GO:0030041 2 0.010
regionalization GO:0003002 274 0.010
protein homooligomerization GO:0051260 3 0.010
carboxylic acid catabolic process GO:0046395 3 0.010
negative regulation of intracellular transport GO:0032387 3 0.010
regulation of neurotransmitter secretion GO:0046928 1 0.010
cytoskeleton organization GO:0007010 96 0.010
camera type eye development GO:0043010 222 0.010

zgc:92022 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.030
nervous system disease DOID:863 0 0.020
disease of metabolism DOID:0014667 0 0.016
musculoskeletal system disease DOID:17 0 0.012
inherited metabolic disorder DOID:655 0 0.012
disease of cellular proliferation DOID:14566 0 0.011
cancer DOID:162 0 0.010
organ system cancer DOID:0050686 0 0.010
immune system disease DOID:2914 0 0.010