Danio rerio

0 known processes

e4bp4-2

E4 binding protein 4-2

e4bp4-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.070
sensory organ development GO:0007423 393 0.049
aging GO:0007568 2 0.045
maintenance of location GO:0051235 4 0.037
positive regulation of catabolic process GO:0009896 4 0.036
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.033
positive regulation of cellular catabolic process GO:0031331 3 0.033
cellular protein catabolic process GO:0044257 4 0.031
ubiquitin dependent protein catabolic process GO:0006511 3 0.031
regulation of multicellular organism growth GO:0040014 4 0.031
modification dependent macromolecule catabolic process GO:0043632 3 0.031
response to chemical GO:0042221 320 0.030
embryonic organ development GO:0048568 381 0.030
eye development GO:0001654 277 0.030
lipid storage GO:0019915 1 0.030
positive regulation of transport GO:0051050 2 0.030
regulation of protein complex assembly GO:0043254 3 0.030
positive regulation of cell cycle GO:0045787 3 0.030
regulation of synaptic plasticity GO:0048167 1 0.029
modification dependent protein catabolic process GO:0019941 3 0.029
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.028
signal transduction GO:0007165 455 0.028
regulation of neural precursor cell proliferation GO:2000177 3 0.028
proteasomal protein catabolic process GO:0010498 2 0.027
multicellular organism growth GO:0035264 4 0.027
compound eye development GO:0048749 2 0.027
stem cell maintenance GO:0019827 4 0.027
cellular aromatic compound metabolic process GO:0006725 295 0.027
regulation of circadian rhythm GO:0042752 4 0.027
regulation of protein catabolic process GO:0042176 1 0.027
cellular carbohydrate metabolic process GO:0044262 4 0.026
cellular response to light stimulus GO:0071482 4 0.026
phagocytosis GO:0006909 3 0.025
negative regulation of protein phosphorylation GO:0001933 4 0.025
regulation of metal ion transport GO:0010959 4 0.024
actin polymerization or depolymerization GO:0008154 2 0.024
adult behavior GO:0030534 2 0.024
cell surface receptor signaling pathway GO:0007166 325 0.024
cellular macromolecule metabolic process GO:0044260 391 0.024
nuclear transport GO:0051169 4 0.024
regulation of biological quality GO:0065008 263 0.023
nitrogen compound metabolic process GO:0006807 319 0.023
cellular response to nutrient levels GO:0031669 2 0.023
single organism metabolic process GO:0044710 217 0.023
cellular nitrogen compound metabolic process GO:0034641 290 0.023
meiotic nuclear division GO:0007126 4 0.023
protein localization to nucleus GO:0034504 3 0.023
cellular response to radiation GO:0071478 4 0.023
amine metabolic process GO:0009308 2 0.023
exocytosis GO:0006887 1 0.023
heterocycle metabolic process GO:0046483 290 0.022
sleep GO:0030431 1 0.022
morphogenesis of an epithelium GO:0002009 333 0.022
camera type eye development GO:0043010 222 0.022
cellular amine metabolic process GO:0044106 2 0.022
cellular biosynthetic process GO:0044249 286 0.022
endosomal transport GO:0016197 2 0.022
establishment of protein localization to organelle GO:0072594 4 0.021
cellular component morphogenesis GO:0032989 336 0.021
stem cell proliferation GO:0072089 4 0.021
cellular response to external stimulus GO:0071496 2 0.021
regulation of transmembrane transporter activity GO:0022898 2 0.021
guanosine containing compound metabolic process GO:1901068 4 0.021
cellular component disassembly GO:0022411 1 0.021
regulation of ion transmembrane transporter activity GO:0032412 2 0.021
regulation of cellular amine metabolic process GO:0033238 0 0.021
protein localization to plasma membrane GO:0072659 1 0.021
positive regulation of cellular component biogenesis GO:0044089 3 0.021
nucleocytoplasmic transport GO:0006913 4 0.021
synaptic vesicle localization GO:0097479 1 0.021
phototransduction visible light GO:0007603 2 0.020
regulation of autophagy GO:0010506 3 0.020
gtp catabolic process GO:0006184 2 0.020
phototransduction GO:0007602 2 0.020
regulation of cytokine production GO:0001817 3 0.020
mitochondrion organization GO:0007005 4 0.020
protein dephosphorylation GO:0006470 3 0.020
regulation of cellular ketone metabolic process GO:0010565 7 0.019
cellular response to extracellular stimulus GO:0031668 2 0.019
startle response GO:0001964 4 0.019
response to drug GO:0042493 3 0.019
embryonic organ morphogenesis GO:0048562 274 0.019
regulation of cell activation GO:0050865 1 0.019
meiotic cell cycle process GO:1903046 3 0.019
regulation of binding GO:0051098 3 0.019
gtp metabolic process GO:0046039 4 0.019
peptidyl serine phosphorylation GO:0018105 1 0.019
cell substrate adhesion GO:0031589 4 0.019
organic cyclic compound metabolic process GO:1901360 301 0.019
regulation of macromolecule metabolic process GO:0060255 317 0.019
cellular nitrogen compound biosynthetic process GO:0044271 218 0.019
guanosine containing compound catabolic process GO:1901069 2 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
g protein coupled receptor signaling pathway GO:0007186 74 0.019
muscle structure development GO:0061061 196 0.019
response to uv GO:0009411 3 0.019
regulation of synapse organization GO:0050807 3 0.019
regulation of muscle contraction GO:0006937 3 0.018
protein import into nucleus GO:0006606 3 0.018
synaptic vesicle transport GO:0048489 1 0.018
cellular ketone metabolic process GO:0042180 11 0.018
regulation of nitrogen compound metabolic process GO:0051171 251 0.018
nucleobase containing compound metabolic process GO:0006139 274 0.018
cellular response to chemical stimulus GO:0070887 157 0.018
ribonucleoside monophosphate catabolic process GO:0009158 4 0.018
biosynthetic process GO:0009058 294 0.018
organic acid metabolic process GO:0006082 31 0.018
protein import GO:0017038 3 0.018
golgi vesicle transport GO:0048193 3 0.018
neuron neuron synaptic transmission GO:0007270 1 0.018
gene expression GO:0010467 252 0.018
vasculature development GO:0001944 278 0.018
autophagy GO:0006914 4 0.018
somatic muscle development GO:0007525 4 0.018
lipid catabolic process GO:0016042 4 0.018
establishment of synaptic vesicle localization GO:0097480 1 0.018
establishment of localization GO:0051234 244 0.018
cytokinesis GO:0000910 3 0.018
oxoacid metabolic process GO:0043436 31 0.018
nucleic acid metabolic process GO:0090304 244 0.018
regulation of cytoplasmic transport GO:1903649 4 0.018
single organism nuclear import GO:1902593 3 0.018
cellular response to starvation GO:0009267 1 0.018
central nervous system development GO:0007417 387 0.018
synaptic growth at neuromuscular junction GO:0051124 2 0.018
negative regulation of protein kinase activity GO:0006469 4 0.018
neurotransmitter secretion GO:0007269 2 0.018
carbon dioxide transport GO:0015670 3 0.017
response to hexose GO:0009746 3 0.017
cell part morphogenesis GO:0032990 246 0.017
positive regulation of protein complex assembly GO:0031334 2 0.017
cell morphogenesis GO:0000902 289 0.017
system process GO:0003008 185 0.017
organic substance biosynthetic process GO:1901576 289 0.017
regulation of sodium ion transport GO:0002028 2 0.017
cell projection morphogenesis GO:0048858 244 0.017
organelle organization GO:0006996 227 0.017
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.017
neuron differentiation GO:0030182 353 0.017
protein targeting to nucleus GO:0044744 3 0.017
negative regulation of kinase activity GO:0033673 4 0.017
generation of neurons GO:0048699 385 0.017
regulation of cellular metabolic process GO:0031323 320 0.017
negative regulation of biological process GO:0048519 304 0.017
regulation of blood pressure GO:0008217 1 0.017
positive regulation of cytoskeleton organization GO:0051495 3 0.017
regulation of transporter activity GO:0032409 2 0.017
regulation of carbohydrate metabolic process GO:0006109 4 0.017
regulation of reproductive process GO:2000241 4 0.017
response to alkaloid GO:0043279 2 0.017
digestive system development GO:0055123 289 0.017
response to topologically incorrect protein GO:0035966 2 0.017
regulation of nucleoside metabolic process GO:0009118 2 0.017
response to carbohydrate GO:0009743 3 0.017
negative regulation of catabolic process GO:0009895 3 0.017
protein polymerization GO:0051258 4 0.016
transport GO:0006810 220 0.016
sensory organ morphogenesis GO:0090596 200 0.016
organelle fusion GO:0048284 3 0.016
retina development in camera type eye GO:0060041 146 0.016
neurotransmitter transport GO:0006836 2 0.016
tube morphogenesis GO:0035239 349 0.016
membrane invagination GO:0010324 1 0.016
atp catabolic process GO:0006200 4 0.016
regulation of protein polymerization GO:0032271 2 0.016
negative regulation of cellular process GO:0048523 283 0.016
regulation of synapse assembly GO:0051963 3 0.016
gastrulation GO:0007369 208 0.016
female gonad development GO:0008585 4 0.016
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.016
purine nucleoside monophosphate catabolic process GO:0009128 4 0.016
regulation of protein ubiquitination GO:0031396 3 0.016
regulation of purine nucleotide catabolic process GO:0033121 2 0.016
nuclear import GO:0051170 3 0.016
carboxylic acid metabolic process GO:0019752 22 0.016
chordate embryonic development GO:0043009 271 0.016
cellular response to oxygen levels GO:0071453 1 0.016
response to external stimulus GO:0009605 264 0.016
homeostatic process GO:0042592 142 0.016
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.016
nucleoside monophosphate catabolic process GO:0009125 4 0.016
small molecule metabolic process GO:0044281 77 0.016
digestive tract morphogenesis GO:0048546 231 0.016
striated muscle cell differentiation GO:0051146 129 0.015
response to monosaccharide GO:0034284 3 0.015
regulation of developmental process GO:0050793 247 0.015
locomotor rhythm GO:0045475 3 0.015
regulation of nucleotide catabolic process GO:0030811 2 0.015
organonitrogen compound metabolic process GO:1901564 74 0.015
regulation of metabolic process GO:0019222 359 0.015
regulation of protein transport GO:0051223 3 0.015
regulation of cellular biosynthetic process GO:0031326 245 0.015
development of primary female sexual characteristics GO:0046545 4 0.015
positive regulation of nucleotide catabolic process GO:0030813 1 0.015
regulation of primary metabolic process GO:0080090 311 0.015
membrane fusion GO:0061025 2 0.015
macromolecule biosynthetic process GO:0009059 227 0.015
regulation of reactive oxygen species metabolic process GO:2000377 2 0.015
regulation of mrna processing GO:0050684 3 0.015
positive regulation of nucleoside metabolic process GO:0045979 1 0.015
internal protein amino acid acetylation GO:0006475 2 0.015
regulation of stem cell proliferation GO:0072091 2 0.015
protein acetylation GO:0006473 2 0.015
regulation of establishment of protein localization GO:0070201 4 0.015
regulation of nucleocytoplasmic transport GO:0046822 2 0.015
rna localization GO:0006403 4 0.015
heterocycle biosynthetic process GO:0018130 215 0.015
actin filament polymerization GO:0030041 2 0.015
peptidyl serine modification GO:0018209 2 0.015
regulation of dendrite development GO:0050773 3 0.014
cellular response to xenobiotic stimulus GO:0071466 35 0.014
protein complex disassembly GO:0043241 1 0.014
chemosensory behavior GO:0007635 1 0.014
rna metabolic process GO:0016070 219 0.014
nuclear migration GO:0007097 3 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.014
neuroblast proliferation GO:0007405 2 0.014
regulation of cellular protein catabolic process GO:1903362 1 0.014
i kappab kinase nf kappab signaling GO:0007249 4 0.014
regulation of sequestering of calcium ion GO:0051282 4 0.014
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.014
heart development GO:0007507 313 0.014
regulation of meiotic cell cycle GO:0051445 1 0.014
regulation of cell shape GO:0008360 1 0.014
negative regulation of synapse assembly GO:0051964 2 0.014
meiotic chromosome segregation GO:0045132 3 0.014
macromolecular complex disassembly GO:0032984 1 0.014
carbohydrate homeostasis GO:0033500 1 0.014
positive regulation of secretion GO:0051047 1 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.014
inner ear development GO:0048839 126 0.014
nucleobase containing compound biosynthetic process GO:0034654 205 0.014
peptide transport GO:0015833 1 0.014
peptidyl lysine acetylation GO:0018394 2 0.014
single organism membrane fusion GO:0044801 2 0.014
carbohydrate biosynthetic process GO:0016051 1 0.014
regulation of gene expression GO:0010468 265 0.014
regulation of protein import into nucleus GO:0042306 2 0.014
cognition GO:0050890 1 0.014
sequestering of metal ion GO:0051238 3 0.014
sequestering of calcium ion GO:0051208 3 0.014
cellular pigmentation GO:0033059 30 0.014
ear development GO:0043583 127 0.014
regulation of intracellular protein transport GO:0033157 3 0.014
regulation of inflammatory response GO:0050727 2 0.014
cellular lipid catabolic process GO:0044242 3 0.014
energy reserve metabolic process GO:0006112 2 0.014
cell projection organization GO:0030030 284 0.014
internal peptidyl lysine acetylation GO:0018393 2 0.014
negative regulation of sequestering of calcium ion GO:0051283 4 0.013
digestive tract development GO:0048565 265 0.013
regulation of biosynthetic process GO:0009889 250 0.013
regulation of blood vessel size GO:0050880 2 0.013
regulation of neuronal synaptic plasticity GO:0048168 1 0.013
regulation of organ growth GO:0046620 3 0.013
cellular component movement GO:0006928 335 0.013
positive regulation of gtp catabolic process GO:0033126 1 0.013
organic cyclic compound biosynthetic process GO:1901362 223 0.013
brain development GO:0007420 293 0.013
establishment of protein localization to plasma membrane GO:0090002 1 0.013
negative regulation of cellular catabolic process GO:0031330 3 0.013
centrosome organization GO:0051297 1 0.013
muscle cell development GO:0055001 115 0.013
protein metabolic process GO:0019538 183 0.013
g2 m transition of mitotic cell cycle GO:0000086 4 0.013
head development GO:0060322 303 0.013
positive regulation of cytokine production GO:0001819 2 0.013
b cell activation GO:0042113 2 0.013
cell migration GO:0016477 237 0.013
peptidyl threonine modification GO:0018210 1 0.013
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.013
regulation of rna metabolic process GO:0051252 224 0.013
regulation of tube size GO:0035150 2 0.013
antimicrobial humoral response GO:0019730 2 0.013
histone h3 k4 methylation GO:0051568 2 0.013
regulation of multicellular organismal process GO:0051239 277 0.013
hatching GO:0035188 4 0.013
single organism localization GO:1902578 225 0.013
phagocytosis engulfment GO:0006911 1 0.013
regulation of cell matrix adhesion GO:0001952 1 0.013
response to stress GO:0006950 263 0.013
pigment granule localization GO:0051875 25 0.013
response to amphetamine GO:0001975 1 0.013
regulation of signal transduction GO:0009966 225 0.013
single organism transport GO:0044765 206 0.013
regulation of dendrite morphogenesis GO:0048814 3 0.013
cellular response to reactive oxygen species GO:0034614 2 0.013
negative regulation of mapk cascade GO:0043409 4 0.013
hormone secretion GO:0046879 2 0.013
ion transmembrane transport GO:0034220 91 0.013
response to nutrient GO:0007584 3 0.013
cellular response to hypoxia GO:0071456 1 0.012
cell substrate junction assembly GO:0007044 2 0.012
response to corticosteroid GO:0031960 1 0.012
regulation of protein localization to nucleus GO:1900180 2 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.012
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.012
regulation of cell communication GO:0010646 232 0.012
leukocyte proliferation GO:0070661 1 0.012
cellular component assembly involved in morphogenesis GO:0010927 107 0.012
regulation of protein binding GO:0043393 3 0.012
mononuclear cell proliferation GO:0032943 1 0.012
adherens junction organization GO:0034332 4 0.012
muscle cell differentiation GO:0042692 139 0.012
regulation of gtpase activity GO:0043087 2 0.012
regulation of cell substrate adhesion GO:0010810 1 0.012
blood circulation GO:0008015 87 0.012
rhodopsin mediated signaling pathway GO:0016056 1 0.012
extrinsic apoptotic signaling pathway GO:0097191 3 0.012
cell matrix adhesion GO:0007160 4 0.012
cell motility GO:0048870 244 0.012
stem cell division GO:0017145 1 0.012
catechol containing compound metabolic process GO:0009712 2 0.012
neuron development GO:0048666 262 0.012
rna biosynthetic process GO:0032774 181 0.012
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.012
regulation of response to stimulus GO:0048583 269 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
blood vessel development GO:0001568 246 0.012
cellular response to organic substance GO:0071310 105 0.012
mitochondrial transport GO:0006839 2 0.012
negative regulation of protein complex assembly GO:0031333 1 0.012
response to glucose GO:0009749 3 0.012
cytoplasm organization GO:0007028 4 0.012
protein acylation GO:0043543 3 0.012
positive regulation of gtpase activity GO:0043547 1 0.012
positive regulation of secretion by cell GO:1903532 1 0.012
cellular amino acid metabolic process GO:0006520 7 0.012
regulation of gtp catabolic process GO:0033124 2 0.012
positive regulation of dna metabolic process GO:0051054 1 0.012
negative regulation of protein transport GO:0051224 3 0.012
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.012
positive regulation of apoptotic signaling pathway GO:2001235 1 0.012
response to endogenous stimulus GO:0009719 83 0.012
single fertilization GO:0007338 3 0.012
regulation of ph GO:0006885 3 0.012
cellular response to decreased oxygen levels GO:0036294 1 0.012
regulation of protein targeting GO:1903533 2 0.012
locomotion GO:0040011 313 0.011
aromatic compound biosynthetic process GO:0019438 217 0.011
secondary metabolic process GO:0019748 3 0.011
single organism organelle organization GO:1902589 199 0.011
synaptic vesicle endocytosis GO:0048488 1 0.011
lipid homeostasis GO:0055088 3 0.011
regulation of stem cell differentiation GO:2000736 4 0.011
localization of cell GO:0051674 244 0.011
synaptic transmission cholinergic GO:0007271 4 0.011
organism emergence from protective structure GO:0071684 4 0.011
gas transport GO:0015669 3 0.011
response to amino acid GO:0043200 2 0.011
response to organic substance GO:0010033 153 0.011
intracellular mrna localization GO:0008298 1 0.011
cellular response to molecule of bacterial origin GO:0071219 3 0.011
alcohol biosynthetic process GO:0046165 2 0.011
catecholamine metabolic process GO:0006584 2 0.011
negative regulation of intracellular transport GO:0032387 3 0.011
microtubule organizing center organization GO:0031023 1 0.011
positive regulation of biological process GO:0048518 253 0.011
female sex differentiation GO:0046660 4 0.011
fertilization GO:0009566 3 0.011
somatic stem cell maintenance GO:0035019 1 0.011
protein homooligomerization GO:0051260 3 0.011
xenobiotic metabolic process GO:0006805 4 0.011
macroautophagy GO:0016236 1 0.011
nucleic acid templated transcription GO:0097659 181 0.011
cellular component biogenesis GO:0044085 178 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.011
cellular component assembly GO:0022607 170 0.011
immune system process GO:0002376 241 0.011
regulation of macromolecule biosynthetic process GO:0010556 225 0.011
regulation of protein complex disassembly GO:0043244 1 0.011
lymphocyte proliferation GO:0046651 1 0.011
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.011
response to xenobiotic stimulus GO:0009410 45 0.011
response to glucocorticoid GO:0051384 1 0.011
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.011
response to other organism GO:0051707 97 0.011
cellular macromolecule biosynthetic process GO:0034645 224 0.011
interspecies interaction between organisms GO:0044419 4 0.011
lateral line system development GO:0048925 76 0.011
positive regulation of protein polymerization GO:0032273 2 0.011
post golgi vesicle mediated transport GO:0006892 1 0.011
vacuolar transport GO:0007034 2 0.011
mitotic dna integrity checkpoint GO:0044774 4 0.011
embryonic skeletal system development GO:0048706 97 0.010
positive regulation of blood circulation GO:1903524 2 0.010
regulation of signaling GO:0023051 235 0.010
ion transport GO:0006811 114 0.010
circulatory system process GO:0003013 87 0.010
negative regulation of cytokine production GO:0001818 1 0.010
negative regulation of defense response GO:0031348 2 0.010
protein polyubiquitination GO:0000209 4 0.010
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.010
sensory perception of chemical stimulus GO:0007606 3 0.010
protein stabilization GO:0050821 2 0.010
striated muscle cell development GO:0055002 108 0.010
circadian sleep wake cycle GO:0042745 2 0.010
embryo development ending in birth or egg hatching GO:0009792 271 0.010
regulation of transcription dna templated GO:0006355 213 0.010
muscle tissue development GO:0060537 110 0.010
smooth muscle contraction GO:0006939 2 0.010
skeletal system development GO:0001501 181 0.010
positive regulation of cell adhesion GO:0045785 1 0.010
regulation of sodium ion transmembrane transport GO:1902305 1 0.010
regulation of growth rate GO:0040009 1 0.010
negative regulation of cytoplasmic transport GO:1903650 2 0.010
olfactory lobe development GO:0021988 4 0.010

e4bp4-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.038
nervous system disease DOID:863 0 0.023
musculoskeletal system disease DOID:17 0 0.018
disease of cellular proliferation DOID:14566 0 0.015
cancer DOID:162 0 0.014
organ system cancer DOID:0050686 0 0.013
disease of metabolism DOID:0014667 0 0.011
cardiovascular system disease DOID:1287 0 0.011
eye disease DOID:5614 0 0.010
sensory system disease DOID:0050155 0 0.010
eye and adnexa disease DOID:1492 0 0.010
inherited metabolic disorder DOID:655 0 0.010