Danio rerio

47 known processes

pmaip1

phorbol-12-myristate-13-acetate-induced protein 1

(Aliases: zgc:162379)

pmaip1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism organelle organization GO:1902589 199 0.480
signal transduction GO:0007165 455 0.253
tube morphogenesis GO:0035239 349 0.218
sequestering of calcium ion GO:0051208 3 0.186
organelle fusion GO:0048284 3 0.181
sequestering of metal ion GO:0051238 3 0.154
actin filament based process GO:0030029 64 0.150
organelle organization GO:0006996 227 0.143
regulation of nucleotide catabolic process GO:0030811 2 0.139
regulation of gtp catabolic process GO:0033124 2 0.131
regulation of biological quality GO:0065008 263 0.130
morphogenesis of an epithelium GO:0002009 333 0.124
gtp catabolic process GO:0006184 2 0.123
positive regulation of biological process GO:0048518 253 0.119
determination of left right symmetry GO:0007368 179 0.116
regulation of developmental process GO:0050793 247 0.106
positive regulation of cellular process GO:0048522 201 0.104
meiosis i GO:0007127 1 0.103
cell cycle g1 s phase transition GO:0044843 1 0.102
guanosine containing compound catabolic process GO:1901069 2 0.101
regulation of gtpase activity GO:0043087 2 0.096
regulation of sequestering of calcium ion GO:0051282 4 0.095
negative regulation of biological process GO:0048519 304 0.092
negative regulation of cellular process GO:0048523 283 0.090
determination of heart left right asymmetry GO:0061371 117 0.089
chordate embryonic development GO:0043009 271 0.088
programmed cell death GO:0012501 119 0.086
regulation of signaling GO:0023051 235 0.086
positive regulation of neuron apoptotic process GO:0043525 1 0.085
guanosine containing compound metabolic process GO:1901068 4 0.083
positive regulation of cellular catabolic process GO:0031331 3 0.083
cation homeostasis GO:0055080 33 0.083
immune system development GO:0002520 191 0.082
positive regulation of catabolic process GO:0009896 4 0.081
protein trimerization GO:0070206 4 0.080
positive regulation of oocyte development GO:0060282 1 0.077
wnt signaling pathway GO:0016055 80 0.075
negative regulation of mitosis GO:0045839 3 0.074
digestive system development GO:0055123 289 0.073
regulation of signal transduction GO:0009966 225 0.072
cytoskeleton organization GO:0007010 96 0.070
regulation of actin filament based movement GO:1903115 1 0.067
cell surface receptor signaling pathway GO:0007166 325 0.067
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.066
regulation of purine nucleotide catabolic process GO:0033121 2 0.066
macromolecular complex subunit organization GO:0043933 74 0.064
cellular modified amino acid metabolic process GO:0006575 3 0.064
angiogenesis GO:0001525 158 0.063
cell cycle GO:0007049 93 0.061
pronephros morphogenesis GO:0072114 14 0.061
fertilization GO:0009566 3 0.061
gtp metabolic process GO:0046039 4 0.060
germ line stem cell division GO:0042078 1 0.060
regulation of nitrogen compound metabolic process GO:0051171 251 0.059
kidney development GO:0001822 92 0.058
regulation of cell communication GO:0010646 232 0.058
negative regulation of signaling GO:0023057 96 0.058
spindle assembly GO:0051225 2 0.057
calcium ion transport into cytosol GO:0060402 3 0.057
cation transport GO:0006812 81 0.055
blood vessel morphogenesis GO:0048514 216 0.055
regulation of nucleotide metabolic process GO:0006140 17 0.055
nuclear export GO:0051168 1 0.054
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.053
maintenance of location GO:0051235 4 0.053
positive regulation of gtp catabolic process GO:0033126 1 0.053
circulatory system process GO:0003013 87 0.053
rna transport GO:0050658 2 0.052
determination of bilateral symmetry GO:0009855 204 0.051
regulation of mitochondrion organization GO:0010821 1 0.050
cognition GO:0050890 1 0.050
intracellular signal transduction GO:0035556 85 0.049
actin filament polymerization GO:0030041 2 0.048
g1 s transition of mitotic cell cycle GO:0000082 1 0.048
biological adhesion GO:0022610 40 0.047
regulation of cell cycle GO:0051726 52 0.047
mitotic cell cycle GO:0000278 64 0.046
positive regulation of gtpase activity GO:0043547 1 0.046
positive regulation of transport GO:0051050 2 0.044
positive regulation of neuron death GO:1901216 1 0.044
developmental growth involved in morphogenesis GO:0060560 86 0.044
regulation of cytoplasmic transport GO:1903649 4 0.044
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.043
reflex GO:0060004 2 0.043
multicellular organism growth GO:0035264 4 0.042
negative regulation of response to stimulus GO:0048585 104 0.041
regulation of intracellular protein transport GO:0033157 3 0.041
regulation of endopeptidase activity GO:0052548 23 0.041
death GO:0016265 121 0.041
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 10 0.040
membrane fusion GO:0061025 2 0.040
positive regulation of nucleotide catabolic process GO:0030813 1 0.040
regulation of primary metabolic process GO:0080090 311 0.039
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.039
regulation of muscle contraction GO:0006937 3 0.039
regulation of striated muscle contraction GO:0006942 2 0.039
regulation of oocyte development GO:0060281 3 0.039
protein polymerization GO:0051258 4 0.038
extrinsic apoptotic signaling pathway GO:0097191 3 0.038
heart development GO:0007507 313 0.038
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.037
phosphorus metabolic process GO:0006793 109 0.037
metal ion transport GO:0030001 58 0.037
negative regulation of signal transduction GO:0009968 94 0.037
positive regulation of cell cycle GO:0045787 3 0.037
synaptic vesicle localization GO:0097479 1 0.036
peptide metabolic process GO:0006518 1 0.036
digestive tract development GO:0048565 265 0.036
convergent extension GO:0060026 118 0.036
single organism transport GO:0044765 206 0.035
cellular component biogenesis GO:0044085 178 0.035
regulation of dendrite development GO:0050773 3 0.034
convergent extension involved in axis elongation GO:0060028 26 0.034
regulation of cardiac muscle contraction GO:0055117 2 0.034
nucleobase containing compound transport GO:0015931 2 0.034
regulation of nucleoside metabolic process GO:0009118 2 0.034
nucleocytoplasmic transport GO:0006913 4 0.034
regulation of purine nucleotide metabolic process GO:1900542 17 0.033
regulation of response to stimulus GO:0048583 269 0.033
phosphate containing compound metabolic process GO:0006796 108 0.033
spindle assembly involved in meiosis GO:0090306 1 0.033
regulation of establishment of protein localization GO:0070201 4 0.033
vasculature development GO:0001944 278 0.033
positive regulation of apoptotic signaling pathway GO:2001235 1 0.033
negative regulation of hormone secretion GO:0046888 2 0.032
establishment of localization GO:0051234 244 0.032
peptide transport GO:0015833 1 0.032
chemical homeostasis GO:0048878 49 0.032
vascular endothelial growth factor receptor signaling pathway GO:0048010 13 0.032
regulation of synaptic plasticity GO:0048167 1 0.032
epithelial tube morphogenesis GO:0060562 148 0.032
negative regulation of nuclear division GO:0051784 3 0.032
cell substrate adhesion GO:0031589 4 0.031
positive regulation of exocytosis GO:0045921 1 0.031
cellular component disassembly GO:0022411 1 0.031
purine containing compound metabolic process GO:0072521 29 0.030
homeostatic process GO:0042592 142 0.030
regulation of meiotic cell cycle GO:0051445 1 0.030
establishment of protein localization to organelle GO:0072594 4 0.030
single organism membrane fusion GO:0044801 2 0.030
female meiotic division GO:0007143 2 0.030
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.029
response to methylmercury GO:0051597 11 0.029
ion homeostasis GO:0050801 41 0.029
macromolecule modification GO:0043412 111 0.029
transport GO:0006810 220 0.028
regulation of bmp signaling pathway GO:0030510 39 0.028
regulation of protein targeting GO:1903533 2 0.028
calcium ion import GO:0070509 4 0.028
regulation of intracellular signal transduction GO:1902531 57 0.028
nuclear transport GO:0051169 4 0.028
histone phosphorylation GO:0016572 2 0.028
positive regulation of reproductive process GO:2000243 2 0.028
ion transport GO:0006811 114 0.028
protein modification process GO:0036211 100 0.028
cytokinesis GO:0000910 3 0.027
regulation of multicellular organism growth GO:0040014 4 0.027
regulation of protein import into nucleus GO:0042306 2 0.027
post embryonic morphogenesis GO:0009886 4 0.026
urogenital system development GO:0001655 97 0.026
cell morphogenesis GO:0000902 289 0.026
water homeostasis GO:0030104 4 0.026
modification dependent macromolecule catabolic process GO:0043632 3 0.026
regulation of erk1 and erk2 cascade GO:0070372 4 0.026
cellular protein catabolic process GO:0044257 4 0.026
protein polyubiquitination GO:0000209 4 0.025
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.025
establishment of localization in cell GO:0051649 77 0.025
specification of symmetry GO:0009799 204 0.025
regulation of anatomical structure morphogenesis GO:0022603 130 0.025
protein complex disassembly GO:0043241 1 0.025
regulation of apoptotic process GO:0042981 98 0.025
spindle assembly involved in mitosis GO:0090307 1 0.025
renal system development GO:0072001 94 0.024
macromolecular complex disassembly GO:0032984 1 0.024
regulation of receptor activity GO:0010469 2 0.024
regulation of cell death GO:0010941 103 0.024
sensory perception of chemical stimulus GO:0007606 3 0.023
regulation of jak stat cascade GO:0046425 3 0.023
embryonic organ development GO:0048568 381 0.023
actin polymerization or depolymerization GO:0008154 2 0.023
proteasomal protein catabolic process GO:0010498 2 0.023
negative regulation of endopeptidase activity GO:0010951 10 0.023
cellular localization GO:0051641 97 0.023
axis elongation GO:0003401 31 0.023
negative regulation of sequestering of calcium ion GO:0051283 4 0.022
cell matrix adhesion GO:0007160 4 0.022
single organism membrane organization GO:0044802 20 0.022
enzyme linked receptor protein signaling pathway GO:0007167 106 0.022
killing of cells in other organism involved in symbiotic interaction GO:0051883 1 0.022
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 3 0.022
release of sequestered calcium ion into cytosol GO:0051209 3 0.022
regulation of phosphate metabolic process GO:0019220 43 0.022
cell aging GO:0007569 2 0.021
positive regulation of cellular metabolic process GO:0031325 94 0.021
regulation of glial cell differentiation GO:0045685 4 0.021
cellular macromolecule metabolic process GO:0044260 391 0.021
negative regulation of proteolysis GO:0045861 10 0.021
lateral line development GO:0048882 66 0.021
divalent inorganic cation homeostasis GO:0072507 22 0.020
b cell differentiation GO:0030183 1 0.020
establishment of organelle localization GO:0051656 45 0.020
nitrogen compound metabolic process GO:0006807 319 0.020
signal transduction in absence of ligand GO:0038034 1 0.020
adult behavior GO:0030534 2 0.020
spindle assembly involved in female meiosis GO:0007056 1 0.020
double strand break repair GO:0006302 3 0.020
hormone secretion GO:0046879 2 0.020
establishment of rna localization GO:0051236 3 0.020
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.020
negative regulation of peptidase activity GO:0010466 10 0.020
positive regulation of multi organism process GO:0043902 3 0.020
positive regulation of cellular component biogenesis GO:0044089 3 0.020
positive regulation of striated muscle cell differentiation GO:0051155 1 0.019
developmental growth GO:0048589 166 0.019
nucleotide metabolic process GO:0009117 28 0.019
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.019
ubiquitin dependent protein catabolic process GO:0006511 3 0.019
establishment of synaptic vesicle localization GO:0097480 1 0.019
regulation of proteolysis GO:0030162 24 0.019
nucleic acid transport GO:0050657 2 0.019
regulation of wnt signaling pathway planar cell polarity pathway GO:2000095 2 0.019
cellular protein metabolic process GO:0044267 129 0.019
regulation of reproductive process GO:2000241 4 0.019
somatic stem cell maintenance GO:0035019 1 0.019
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.019
intrinsic apoptotic signaling pathway GO:0097193 20 0.019
exocytosis GO:0006887 1 0.019
protein metabolic process GO:0019538 183 0.019
transmembrane transport GO:0055085 120 0.019
growth GO:0040007 174 0.018
negative regulation of cell communication GO:0010648 96 0.018
hematopoietic or lymphoid organ development GO:0048534 191 0.018
cytosolic calcium ion transport GO:0060401 3 0.018
hormone biosynthetic process GO:0042446 3 0.018
steroid hormone secretion GO:0035929 1 0.018
regulation of cardiac muscle cell contraction GO:0086004 1 0.018
metal ion homeostasis GO:0055065 26 0.018
digestive tract morphogenesis GO:0048546 231 0.018
sensory perception of pain GO:0019233 1 0.018
response to nutrient GO:0007584 3 0.018
regulation of synapse organization GO:0050807 3 0.018
regulation of metabolic process GO:0019222 359 0.018
nuclear division GO:0000280 23 0.018
response to stress GO:0006950 263 0.017
killing of cells of other organism GO:0031640 1 0.017
cellular amide metabolic process GO:0043603 4 0.017
regulation of nucleocytoplasmic transport GO:0046822 2 0.017
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 7 0.017
chromosome organization involved in meiosis GO:0070192 1 0.017
epiboly GO:0090504 41 0.017
regulation of binding GO:0051098 3 0.017
circadian sleep wake cycle sleep GO:0050802 1 0.017
blood circulation GO:0008015 87 0.017
head development GO:0060322 303 0.017
regulation of hormone secretion GO:0046883 2 0.017
blood vessel development GO:0001568 246 0.017
cell death GO:0008219 121 0.017
cleavage furrow formation GO:0036089 2 0.017
determination of ventral identity GO:0048264 21 0.017
organic cyclic compound metabolic process GO:1901360 301 0.017
secondary metabolic process GO:0019748 3 0.017
g protein coupled receptor signaling pathway GO:0007186 74 0.016
regulation of cardiac muscle tissue development GO:0055024 1 0.016
centrosome duplication GO:0051298 1 0.016
cellular response to light stimulus GO:0071482 4 0.016
meiotic spindle organization GO:0000212 1 0.016
negative regulation of wnt signaling pathway GO:0030178 30 0.016
pronuclear migration GO:0035046 1 0.016
organonitrogen compound metabolic process GO:1901564 74 0.016
tissue remodeling GO:0048771 4 0.016
telomere organization GO:0032200 1 0.016
meiotic cell cycle process GO:1903046 3 0.016
regulation of molecular function GO:0065009 70 0.016
mitotic cell cycle process GO:1903047 48 0.016
protein depolymerization GO:0051261 1 0.016
positive regulation of metabolic process GO:0009893 108 0.015
response to drug GO:0042493 3 0.015
regulation of metal ion transport GO:0010959 4 0.015
negative regulation of i kappab kinase nf kappab signaling GO:0043124 1 0.015
canonical wnt signaling pathway involved in neural plate anterior posterior pattern formation GO:0060823 4 0.015
nucleobase containing small molecule metabolic process GO:0055086 32 0.015
protein processing GO:0016485 12 0.015
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.015
odontogenesis of dentin containing tooth GO:0042475 1 0.015
regulation of protein transport GO:0051223 3 0.015
rrna catabolic process GO:0016075 1 0.015
cell killing GO:0001906 2 0.015
positive regulation of cell killing GO:0031343 2 0.015
single fertilization GO:0007338 3 0.015
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.015
embryonic heart tube morphogenesis GO:0003143 108 0.015
actin filament based movement GO:0030048 1 0.014
proteolysis GO:0006508 38 0.014
negative regulation of cytoplasmic transport GO:1903650 2 0.014
positive regulation of programmed cell death GO:0043068 29 0.014
positive regulation of response to stimulus GO:0048584 80 0.014
immune system process GO:0002376 241 0.014
vesicle localization GO:0051648 27 0.014
regulation of protein complex disassembly GO:0043244 1 0.014
neuromast development GO:0048884 46 0.014
rna localization GO:0006403 4 0.014
positive regulation of secretion by cell GO:1903532 1 0.014
stem cell division GO:0017145 1 0.014
cellular divalent inorganic cation homeostasis GO:0072503 13 0.014
centrosome organization GO:0051297 1 0.014
entrainment of circadian clock by photoperiod GO:0043153 1 0.014
negative regulation of protein processing GO:0010955 10 0.014
cytoskeleton dependent cytokinesis GO:0061640 3 0.014
hard palate development GO:0060022 4 0.014
nuclear migration GO:0007097 3 0.014
ion transmembrane transport GO:0034220 91 0.014
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.014
nuclear import GO:0051170 3 0.014
mitotic nuclear division GO:0007067 18 0.014
protein complex localization GO:0031503 1 0.013
regulation of exocytosis GO:0017157 1 0.013
endocrine hormone secretion GO:0060986 2 0.013
positive regulation of catalytic activity GO:0043085 25 0.013
apoptotic process GO:0006915 116 0.013
establishment of vesicle localization GO:0051650 24 0.013
catabolic process GO:0009056 32 0.013
regulation of establishment of planar polarity GO:0090175 4 0.013
lipid metabolic process GO:0006629 52 0.013
regulation of production of molecular mediator of immune response GO:0002700 1 0.013
hatching GO:0035188 4 0.013
positive regulation of peptidase activity GO:0010952 10 0.013
regulation of chromosome segregation GO:0051983 1 0.013
anterior head development GO:0097065 2 0.013
neuron death GO:0070997 21 0.013
sodium ion transmembrane transport GO:0035725 21 0.013
regulation of cell maturation GO:1903429 1 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.013
actin mediated cell contraction GO:0070252 1 0.013
hemopoiesis GO:0030097 183 0.013
single organism metabolic process GO:0044710 217 0.012
regulation of endocrine process GO:0044060 2 0.012
interaction with host GO:0051701 4 0.012
regulation of programmed cell death GO:0043067 101 0.012
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.012
protein complex subunit organization GO:0071822 46 0.012
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 8 0.012
primary neural tube formation GO:0014020 1 0.012
i kappab kinase nf kappab signaling GO:0007249 4 0.012
myeloid cell differentiation GO:0030099 86 0.012
positive regulation of glucose transport GO:0010828 1 0.012
gene expression GO:0010467 252 0.012
smoothened signaling pathway GO:0007224 30 0.012
protein dephosphorylation GO:0006470 3 0.012
bmp signaling pathway GO:0030509 52 0.012
calcium ion dependent exocytosis GO:0017156 1 0.012
protein targeting to nucleus GO:0044744 3 0.012
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.012
regulation of cell killing GO:0031341 2 0.012
neural crest cell differentiation GO:0014033 72 0.012
meiotic nuclear division GO:0007126 4 0.012
regulation of cysteine type endopeptidase activity GO:2000116 21 0.012
regulation of rho protein signal transduction GO:0035023 2 0.012
spliceosomal snrnp assembly GO:0000387 2 0.012
positive regulation of immune effector process GO:0002699 3 0.012
negative regulation of signal transduction in absence of ligand GO:1901099 1 0.012
endocrine process GO:0050886 2 0.012
ribose phosphate metabolic process GO:0019693 27 0.012
negative regulation of protein maturation GO:1903318 10 0.012
regulation of membrane potential GO:0042391 23 0.012
calcium mediated signaling GO:0019722 2 0.012
cellular response to extracellular stimulus GO:0031668 2 0.012
ribosomal small subunit biogenesis GO:0042274 2 0.011
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 17 0.011
cell type specific apoptotic process GO:0097285 22 0.011
regulation of protein complex assembly GO:0043254 3 0.011
positive regulation of proteolysis GO:0045862 10 0.011
amine metabolic process GO:0009308 2 0.011
lymphocyte homeostasis GO:0002260 1 0.011
calcium ion homeostasis GO:0055074 19 0.011
cytokinetic process GO:0032506 2 0.011
negative regulation of protein localization to nucleus GO:1900181 2 0.011
heart morphogenesis GO:0003007 156 0.011
cellular component assembly GO:0022607 170 0.011
determination of dorsal ventral asymmetry GO:0048262 34 0.011
carboxylic acid metabolic process GO:0019752 22 0.011
segmentation GO:0035282 97 0.011
cellular response to radiation GO:0071478 4 0.011
mrna transport GO:0051028 2 0.011
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.011
protein complex biogenesis GO:0070271 30 0.011
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 20 0.011
mitochondrion organization GO:0007005 4 0.011
modification dependent protein catabolic process GO:0019941 3 0.011
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.011
primary amino compound metabolic process GO:1901160 1 0.011
regulation of cellular protein catabolic process GO:1903362 1 0.011
mitotic cytokinesis GO:0000281 3 0.011
negative regulation of cell cycle GO:0045786 14 0.010
negative regulation of intracellular transport GO:0032387 3 0.010
meiosis ii GO:0007135 1 0.010
cellular response to decreased oxygen levels GO:0036294 1 0.010
regulation of protein depolymerization GO:1901879 1 0.010
positive regulation of cysteine type endopeptidase activity GO:2001056 10 0.010
apoptotic process involved in development GO:1902742 2 0.010
positive regulation of cell communication GO:0010647 56 0.010
disruption of cells of other organism GO:0044364 1 0.010
regulation of cellular amine metabolic process GO:0033238 0 0.010
cellular component movement GO:0006928 335 0.010
positive regulation of endopeptidase activity GO:0010950 10 0.010
regulation of cellular response to oxidative stress GO:1900407 2 0.010
cellular nitrogen compound metabolic process GO:0034641 290 0.010
cortical cytoskeleton organization GO:0030865 1 0.010
gastrulation GO:0007369 208 0.010

pmaip1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.075
disease of cellular proliferation DOID:14566 0 0.075
disease of metabolism DOID:0014667 0 0.038
inherited metabolic disorder DOID:655 0 0.038
organ system cancer DOID:0050686 0 0.036
disease of anatomical entity DOID:7 0 0.032
myopathy DOID:423 0 0.026
muscular disease DOID:0080000 0 0.026
heart disease DOID:114 0 0.026
cardiomyopathy DOID:0050700 0 0.026
cardiovascular system disease DOID:1287 0 0.026
musculoskeletal system disease DOID:17 0 0.026
muscle tissue disease DOID:66 0 0.026
intrinsic cardiomyopathy DOID:0060036 0 0.023
immune system disease DOID:2914 0 0.013
bone marrow disease DOID:4961 0 0.013
hematopoietic system disease DOID:74 0 0.013
gastrointestinal system cancer DOID:3119 0 0.012