Danio rerio

0 known processes

mdh1a

malate dehydrogenase 1a, NAD (soluble)

(Aliases: fj05b08,zgc:63941,mdhA,MDH1,wu:fj05b08)

mdh1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
branched chain amino acid metabolic process GO:0009081 1 0.486
locomotion GO:0040011 313 0.388
alpha amino acid metabolic process GO:1901605 3 0.304
organic acid catabolic process GO:0016054 3 0.300
small molecule metabolic process GO:0044281 77 0.298
aging GO:0007568 2 0.275
regulation of biological quality GO:0065008 263 0.259
maintenance of location GO:0051235 4 0.203
hydrogen peroxide metabolic process GO:0042743 2 0.201
cellular amino acid metabolic process GO:0006520 7 0.192
carboxylic acid catabolic process GO:0046395 3 0.191
regulation of multicellular organism growth GO:0040014 4 0.182
organic acid metabolic process GO:0006082 31 0.178
dicarboxylic acid metabolic process GO:0043648 1 0.164
larval development GO:0002164 2 0.162
alcohol biosynthetic process GO:0046165 2 0.149
small molecule catabolic process GO:0044282 3 0.147
regulation of macromolecule metabolic process GO:0060255 317 0.120
cellular carbohydrate metabolic process GO:0044262 4 0.116
multicellular organism growth GO:0035264 4 0.113
embryonic organ morphogenesis GO:0048562 274 0.100
nitrogen compound metabolic process GO:0006807 319 0.100
cellular nitrogen compound metabolic process GO:0034641 290 0.097
digestive system development GO:0055123 289 0.097
establishment of localization GO:0051234 244 0.093
pyruvate metabolic process GO:0006090 1 0.093
response to external stimulus GO:0009605 264 0.090
cellular component assembly involved in morphogenesis GO:0010927 107 0.090
carbohydrate derivative metabolic process GO:1901135 61 0.084
single organism metabolic process GO:0044710 217 0.084
Fly
regulation of cell communication GO:0010646 232 0.079
embryonic organ development GO:0048568 381 0.078
inner ear morphogenesis GO:0042472 63 0.077
carboxylic acid metabolic process GO:0019752 22 0.076
brain development GO:0007420 293 0.074
cellular amino acid biosynthetic process GO:0008652 2 0.071
developmental growth GO:0048589 166 0.070
single organism transport GO:0044765 206 0.067
response to chemical GO:0042221 320 0.065
lipid storage GO:0019915 1 0.064
tube morphogenesis GO:0035239 349 0.064
nucleic acid metabolic process GO:0090304 244 0.062
regulation of signaling GO:0023051 235 0.062
regulation of cellular metabolic process GO:0031323 320 0.062
ion transport GO:0006811 114 0.062
transport GO:0006810 220 0.059
cellular aromatic compound metabolic process GO:0006725 295 0.057
positive regulation of map kinase activity GO:0043406 3 0.056
nucleobase containing compound metabolic process GO:0006139 274 0.056
inner ear development GO:0048839 126 0.056
organonitrogen compound metabolic process GO:1901564 74 0.054
energy reserve metabolic process GO:0006112 2 0.052
cytoskeleton organization GO:0007010 96 0.050
regulation of protein transport GO:0051223 3 0.050
response to stress GO:0006950 263 0.049
organic cyclic compound metabolic process GO:1901360 301 0.048
fluid transport GO:0042044 17 0.047
phosphate containing compound metabolic process GO:0006796 108 0.047
embryo development ending in birth or egg hatching GO:0009792 271 0.046
purine containing compound metabolic process GO:0072521 29 0.043
nucleoside monophosphate catabolic process GO:0009125 4 0.043
ear morphogenesis GO:0042471 64 0.043
cellular ketone metabolic process GO:0042180 11 0.042
astrocyte differentiation GO:0048708 1 0.042
cellular biosynthetic process GO:0044249 286 0.042
regulation of autophagy GO:0010506 3 0.042
gland development GO:0048732 143 0.040
ear development GO:0043583 127 0.039
response to oxygen radical GO:0000305 2 0.039
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.039
regulation of response to stimulus GO:0048583 269 0.038
positive regulation of cellular process GO:0048522 201 0.038
morphogenesis of an epithelium GO:0002009 333 0.037
nitrogen compound transport GO:0071705 23 0.037
carbohydrate biosynthetic process GO:0016051 1 0.037
urogenital system development GO:0001655 97 0.037
phagocytosis engulfment GO:0006911 1 0.037
digestive tract development GO:0048565 265 0.037
regulation of establishment of protein localization GO:0070201 4 0.037
epithelial cell differentiation GO:0030855 116 0.037
spermatid differentiation GO:0048515 2 0.037
sensory organ development GO:0007423 393 0.036
homeostatic process GO:0042592 142 0.036
electron transport chain GO:0022900 2 0.035
negative regulation of heart contraction GO:0045822 2 0.035
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.034
cellular component morphogenesis GO:0032989 336 0.034
regulation of nucleoside metabolic process GO:0009118 2 0.034
transmembrane transport GO:0055085 120 0.033
regulation of metal ion transport GO:0010959 4 0.033
single organism organelle organization GO:1902589 199 0.033
gastrulation GO:0007369 208 0.033
inositol lipid mediated signaling GO:0048017 2 0.033
response to organic substance GO:0010033 153 0.033
response to nutrient GO:0007584 3 0.031
heterocycle metabolic process GO:0046483 290 0.031
phosphorus metabolic process GO:0006793 109 0.031
cellular nitrogen compound biosynthetic process GO:0044271 218 0.031
biosynthetic process GO:0009058 294 0.030
organonitrogen compound biosynthetic process GO:1901566 47 0.030
oxoacid metabolic process GO:0043436 31 0.030
single organism localization GO:1902578 225 0.030
regulation of transmembrane transporter activity GO:0022898 2 0.030
regulation of metabolic process GO:0019222 359 0.030
cation transport GO:0006812 81 0.029
cell migration GO:0016477 237 0.029
amine metabolic process GO:0009308 2 0.029
growth GO:0040007 174 0.028
signal transduction GO:0007165 455 0.028
iron ion homeostasis GO:0055072 4 0.028
cellular amine metabolic process GO:0044106 2 0.028
regulation of cytoplasmic transport GO:1903649 4 0.027
response to superoxide GO:0000303 2 0.027
connective tissue development GO:0061448 99 0.027
neurotransmitter transport GO:0006836 2 0.027
central nervous system development GO:0007417 387 0.027
response to drug GO:0042493 3 0.027
response to abiotic stimulus GO:0009628 122 0.027
nuclear transport GO:0051169 4 0.027
intracellular signal transduction GO:0035556 85 0.027
renal system development GO:0072001 94 0.027
positive regulation of transport GO:0051050 2 0.026
proximal tubule development GO:0072014 3 0.026
sensory organ morphogenesis GO:0090596 200 0.026
zymogen activation GO:0031638 3 0.026
membrane invagination GO:0010324 1 0.026
ion homeostasis GO:0050801 41 0.026
s adenosylmethionine metabolic process GO:0046500 1 0.026
actin cytoskeleton organization GO:0030036 63 0.025
protein localization to plasma membrane GO:0072659 1 0.025
phagocytosis GO:0006909 3 0.025
positive regulation of secretion by cell GO:1903532 1 0.025
liver development GO:0001889 96 0.025
regulation of cell shape GO:0008360 1 0.024
regulation of nitrogen compound metabolic process GO:0051171 251 0.024
cellular homeostasis GO:0019725 26 0.023
transcription from rna polymerase ii promoter GO:0006366 80 0.023
response to hypoxia GO:0001666 25 0.023
system process GO:0003008 185 0.023
lateral line system development GO:0048925 76 0.023
positive regulation of biological process GO:0048518 253 0.022
cation transmembrane transport GO:0098655 65 0.022
cellular component movement GO:0006928 335 0.022
response to corticosteroid GO:0031960 1 0.022
purine nucleoside monophosphate catabolic process GO:0009128 4 0.022
death GO:0016265 121 0.022
lateral line development GO:0048882 66 0.022
negative regulation of blood circulation GO:1903523 2 0.021
organophosphate metabolic process GO:0019637 37 0.021
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.021
protein homooligomerization GO:0051260 3 0.021
regulation of protein localization to nucleus GO:1900180 2 0.021
organic cyclic compound biosynthetic process GO:1901362 223 0.021
protein oligomerization GO:0051259 7 0.021
regulation of cellular biosynthetic process GO:0031326 245 0.020
organic substance biosynthetic process GO:1901576 289 0.020
ribonucleoside monophosphate catabolic process GO:0009158 4 0.020
nephron epithelium development GO:0072009 16 0.020
synaptic growth at neuromuscular junction GO:0051124 2 0.020
heart development GO:0007507 313 0.019
skin development GO:0043588 54 0.019
positive regulation of catabolic process GO:0009896 4 0.019
cell cell signaling GO:0007267 52 0.019
Fly
renal absorption GO:0070293 1 0.019
gene expression GO:0010467 252 0.019
apoptotic process GO:0006915 116 0.019
cell morphogenesis GO:0000902 289 0.019
skeletal system development GO:0001501 181 0.019
cellular response to chemical stimulus GO:0070887 157 0.018
regulation of striated muscle contraction GO:0006942 2 0.018
metal ion homeostasis GO:0055065 26 0.018
regulation of primary metabolic process GO:0080090 311 0.018
regulation of cell activation GO:0050865 1 0.018
regulation of purine nucleotide catabolic process GO:0033121 2 0.018
cellular component assembly GO:0022607 170 0.018
cellular component biogenesis GO:0044085 178 0.018
neuron neuron synaptic transmission GO:0007270 1 0.018
stem cell maintenance GO:0019827 4 0.018
adult behavior GO:0030534 2 0.018
epidermis development GO:0008544 48 0.017
regulation of rna biosynthetic process GO:2001141 213 0.017
macromolecular complex subunit organization GO:0043933 74 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.017
monovalent inorganic cation transport GO:0015672 42 0.017
camera type eye development GO:0043010 222 0.017
neuron development GO:0048666 262 0.017
macromolecular complex assembly GO:0065003 35 0.017
peptide transport GO:0015833 1 0.017
organelle assembly GO:0070925 110 0.017
heterocycle biosynthetic process GO:0018130 215 0.017
centrosome organization GO:0051297 1 0.017
positive regulation of secretion GO:0051047 1 0.017
immune system process GO:0002376 241 0.016
lipid oxidation GO:0034440 1 0.016
regulation of blood pressure GO:0008217 1 0.016
sulfur compound metabolic process GO:0006790 13 0.016
response to oxygen levels GO:0070482 25 0.016
hematopoietic or lymphoid organ development GO:0048534 191 0.016
regulation of cellular amine metabolic process GO:0033238 0 0.016
mononuclear cell proliferation GO:0032943 1 0.016
regulation of intracellular protein transport GO:0033157 3 0.016
actin filament based process GO:0030029 64 0.016
positive regulation of signaling GO:0023056 56 0.016
atp catabolic process GO:0006200 4 0.016
cellular transition metal ion homeostasis GO:0046916 3 0.016
cellular response to oxygen radical GO:0071450 2 0.016
cellular component disassembly GO:0022411 1 0.015
response to vitamin GO:0033273 3 0.015
ovulation cycle GO:0042698 2 0.015
regulation of muscle contraction GO:0006937 3 0.015
glucose homeostasis GO:0042593 1 0.015
regulation of signal transduction GO:0009966 225 0.015
axonogenesis GO:0007409 152 0.015
nucleic acid transport GO:0050657 2 0.015
cellular response to external stimulus GO:0071496 2 0.015
regulation of cellular ketone metabolic process GO:0010565 7 0.015
ovulation cycle process GO:0022602 2 0.015
single organism biosynthetic process GO:0044711 71 0.015
somatic muscle development GO:0007525 4 0.015
sensory system development GO:0048880 76 0.015
response to hexose GO:0009746 3 0.015
nucleobase containing compound transport GO:0015931 2 0.015
regulation of localization GO:0032879 104 0.015
lateral inhibition GO:0046331 1 0.015
Fly
regulation of dna templated transcription in response to stress GO:0043620 0 0.015
negative regulation of dna replication GO:0008156 2 0.014
response to endogenous stimulus GO:0009719 83 0.014
generation of neurons GO:0048699 385 0.014
positive regulation of jak stat cascade GO:0046427 2 0.014
determination of bilateral symmetry GO:0009855 204 0.014
female sex differentiation GO:0046660 4 0.014
reactive oxygen species metabolic process GO:0072593 6 0.014
regulation of nucleotide catabolic process GO:0030811 2 0.014
insulin like growth factor receptor signaling pathway GO:0048009 4 0.014
cellular nitrogen compound catabolic process GO:0044270 15 0.014
superoxide metabolic process GO:0006801 2 0.014
positive regulation of cell communication GO:0010647 56 0.014
glycerolipid biosynthetic process GO:0045017 1 0.014
response to lipid GO:0033993 60 0.014
carbohydrate homeostasis GO:0033500 1 0.014
actomyosin structure organization GO:0031032 53 0.014
cartilage development GO:0051216 96 0.014
catabolic process GO:0009056 32 0.014
ion transmembrane transport GO:0034220 91 0.014
neurotransmitter secretion GO:0007269 2 0.014
macromolecular complex disassembly GO:0032984 1 0.014
gtp metabolic process GO:0046039 4 0.013
chemical homeostasis GO:0048878 49 0.013
nucleobase containing compound biosynthetic process GO:0034654 205 0.013
kidney development GO:0001822 92 0.013
lipid metabolic process GO:0006629 52 0.013
transcription dna templated GO:0006351 181 0.013
glycerol transport GO:0015793 7 0.013
autophagy GO:0006914 4 0.013
cell death GO:0008219 121 0.013
organic acid biosynthetic process GO:0016053 12 0.013
protein localization to nucleus GO:0034504 3 0.013
aromatic compound biosynthetic process GO:0019438 217 0.013
response to carbohydrate GO:0009743 3 0.013
negative regulation of multicellular organismal process GO:0051241 69 0.013
negative regulation of intracellular transport GO:0032387 3 0.013
female gonad development GO:0008585 4 0.013
protein import GO:0017038 3 0.013
heterocycle catabolic process GO:0046700 15 0.013
protein complex assembly GO:0006461 30 0.013
head development GO:0060322 303 0.013
single organism nuclear import GO:1902593 3 0.013
lymphocyte proliferation GO:0046651 1 0.013
positive regulation of transcription dna templated GO:0045893 57 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
eye development GO:0001654 277 0.012
adipose tissue development GO:0060612 1 0.012
regulation of biosynthetic process GO:0009889 250 0.012
g1 s transition of mitotic cell cycle GO:0000082 1 0.012
organic substance catabolic process GO:1901575 28 0.012
respiratory electron transport chain GO:0022904 2 0.012
small molecule biosynthetic process GO:0044283 16 0.012
cognition GO:0050890 1 0.012
polyol metabolic process GO:0019751 1 0.012
regulation of developmental growth GO:0048638 38 0.012
pectoral fin development GO:0033339 50 0.012
leukocyte proliferation GO:0070661 1 0.012
purine nucleotide metabolic process GO:0006163 27 0.012
cellular catabolic process GO:0044248 27 0.012
multicellular organismal response to stress GO:0033555 2 0.012
cell motility GO:0048870 244 0.012
response to organic cyclic compound GO:0014070 51 0.012
digestive tract morphogenesis GO:0048546 231 0.012
striated muscle cell development GO:0055002 108 0.012
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.012
long chain fatty acid transport GO:0015909 1 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.012
cellular protein metabolic process GO:0044267 129 0.012
nucleic acid templated transcription GO:0097659 181 0.012
regulation of transporter activity GO:0032409 2 0.012
protein metabolic process GO:0019538 183 0.012
cellular macromolecule metabolic process GO:0044260 391 0.011
protein import into nucleus GO:0006606 3 0.011
activation of mapk activity GO:0000187 3 0.011
cell aging GO:0007569 2 0.011
nucleocytoplasmic transport GO:0006913 4 0.011
cellular localization GO:0051641 97 0.011
cofactor metabolic process GO:0051186 15 0.011
meiotic cell cycle process GO:1903046 3 0.011
regulation of multicellular organismal process GO:0051239 277 0.011
response to glucose GO:0009749 3 0.011
regulation of carbohydrate metabolic process GO:0006109 4 0.011
negative regulation of cytoplasmic transport GO:1903650 2 0.011
carboxylic acid biosynthetic process GO:0046394 12 0.011
response to hormone GO:0009725 48 0.011
cell cycle g1 s phase transition GO:0044843 1 0.011
regulation of dna replication GO:0006275 3 0.011
muscle structure development GO:0061061 196 0.011
microtubule organizing center organization GO:0031023 1 0.011
negative regulation of neural precursor cell proliferation GO:2000178 1 0.011
neuron differentiation GO:0030182 353 0.011
negative regulation of dna metabolic process GO:0051053 4 0.011
septum transversum development GO:0003343 4 0.011
dopamine biosynthetic process GO:0042416 2 0.011
positive regulation of cellular metabolic process GO:0031325 94 0.011
regulation of rho protein signal transduction GO:0035023 2 0.011
ribonucleotide metabolic process GO:0009259 27 0.011
heart morphogenesis GO:0003007 156 0.011
response to transition metal nanoparticle GO:1990267 28 0.011
negative regulation of developmental process GO:0051093 65 0.011
regulation of cell substrate adhesion GO:0010810 1 0.011
glycosyl compound metabolic process GO:1901657 11 0.011
macromolecule localization GO:0033036 54 0.011
protein complex biogenesis GO:0070271 30 0.011
cell projection organization GO:0030030 284 0.010
mechanoreceptor differentiation GO:0042490 37 0.010
cellular response to organic substance GO:0071310 105 0.010
embryonic heart tube morphogenesis GO:0003143 108 0.010
purine ribonucleotide metabolic process GO:0009150 27 0.010
response to monosaccharide GO:0034284 3 0.010
regulation of fatty acid metabolic process GO:0019217 1 0.010
positive regulation of cellular catabolic process GO:0031331 3 0.010
cellular response to lipid GO:0071396 39 0.010
regulation of gtp catabolic process GO:0033124 2 0.010
positive regulation of programmed cell death GO:0043068 29 0.010
positive regulation of nucleoside metabolic process GO:0045979 1 0.010
nucleobase containing small molecule metabolic process GO:0055086 32 0.010

mdh1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.143
inherited metabolic disorder DOID:655 0 0.061
disease of anatomical entity DOID:7 0 0.044
nervous system disease DOID:863 0 0.037
amino acid metabolic disorder DOID:9252 0 0.023
musculoskeletal system disease DOID:17 0 0.012