Danio rerio

0 known processes

smek2

SMEK homolog 2, suppressor of mek1 (Dictyostelium)

(Aliases: zgc:77352,flfl,zgc:56492,wu:fj55c11)

smek2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of mrna processing GO:0050684 3 0.377
regulation of mrna splicing via spliceosome GO:0048024 3 0.269
larval development GO:0002164 2 0.207
cellular aromatic compound metabolic process GO:0006725 295 0.196
heterocycle metabolic process GO:0046483 290 0.187
alternative mrna splicing via spliceosome GO:0000380 1 0.179
cellular nitrogen compound biosynthetic process GO:0044271 218 0.177
locomotion GO:0040011 313 0.172
regulation of metabolic process GO:0019222 359 0.172
gene expression GO:0010467 252 0.167
aromatic compound biosynthetic process GO:0019438 217 0.147
nitrogen compound metabolic process GO:0006807 319 0.146
cellular nitrogen compound metabolic process GO:0034641 290 0.145
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.144
nucleic acid metabolic process GO:0090304 244 0.119
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.119
regulation of cellular metabolic process GO:0031323 320 0.109
nucleobase containing compound metabolic process GO:0006139 274 0.108
regulation of nitrogen compound metabolic process GO:0051171 251 0.107
organism emergence from protective structure GO:0071684 4 0.087
multi organism process GO:0051704 134 0.086
cellular macromolecule metabolic process GO:0044260 391 0.077
cellular biosynthetic process GO:0044249 286 0.075
organic substance biosynthetic process GO:1901576 289 0.073
nucleocytoplasmic transport GO:0006913 4 0.068
regulation of nucleocytoplasmic transport GO:0046822 2 0.067
rna metabolic process GO:0016070 219 0.066
lipid storage GO:0019915 1 0.065
regulation of rna biosynthetic process GO:2001141 213 0.064
regulation of macromolecule metabolic process GO:0060255 317 0.064
heterocycle biosynthetic process GO:0018130 215 0.062
positive regulation of cellular process GO:0048522 201 0.062
nuclear transport GO:0051169 4 0.062
regulation of primary metabolic process GO:0080090 311 0.061
organic cyclic compound metabolic process GO:1901360 301 0.061
cellular component assembly GO:0022607 170 0.057
aging GO:0007568 2 0.056
transcription dna templated GO:0006351 181 0.055
cell migration GO:0016477 237 0.055
embryo development ending in birth or egg hatching GO:0009792 271 0.054
nucleic acid templated transcription GO:0097659 181 0.054
nucleobase containing compound biosynthetic process GO:0034654 205 0.053
protein localization to nucleus GO:0034504 3 0.053
regulation of response to stimulus GO:0048583 269 0.050
cell surface receptor signaling pathway GO:0007166 325 0.049
locomotor rhythm GO:0045475 3 0.048
regulation of biological quality GO:0065008 263 0.047
regulation of gene expression GO:0010468 265 0.046
signal transduction GO:0007165 455 0.046
regulation of cellular biosynthetic process GO:0031326 245 0.045
rna biosynthetic process GO:0032774 181 0.045
macromolecule biosynthetic process GO:0009059 227 0.044
establishment of localization GO:0051234 244 0.044
cellular component movement GO:0006928 335 0.044
response to stress GO:0006950 263 0.044
single organism organelle organization GO:1902589 199 0.044
cellular macromolecule biosynthetic process GO:0034645 224 0.043
positive regulation of catabolic process GO:0009896 4 0.042
biosynthetic process GO:0009058 294 0.042
regulation of rna metabolic process GO:0051252 224 0.042
maintenance of location GO:0051235 4 0.041
hatching GO:0035188 4 0.041
organic cyclic compound biosynthetic process GO:1901362 223 0.040
organelle organization GO:0006996 227 0.040
generation of neurons GO:0048699 385 0.040
positive regulation of biological process GO:0048518 253 0.039
response to carbohydrate GO:0009743 3 0.038
mitotic cell cycle GO:0000278 64 0.038
single organism nuclear import GO:1902593 3 0.038
regulation of dendrite morphogenesis GO:0048814 3 0.038
cellular component biogenesis GO:0044085 178 0.037
spermatid development GO:0007286 2 0.037
single organism metabolic process GO:0044710 217 0.037
negative regulation of chromosome organization GO:2001251 1 0.035
rna splicing GO:0008380 16 0.033
regulation of cytoplasmic transport GO:1903649 4 0.033
death GO:0016265 121 0.033
negative regulation of metabolic process GO:0009892 86 0.033
macromolecular complex subunit organization GO:0043933 74 0.033
reproduction GO:0000003 40 0.033
regulation of multicellular organismal development GO:2000026 223 0.031
localization of cell GO:0051674 244 0.031
glucose homeostasis GO:0042593 1 0.030
neuron differentiation GO:0030182 353 0.030
organonitrogen compound metabolic process GO:1901564 74 0.030
mrna metabolic process GO:0016071 20 0.028
establishment of protein localization to organelle GO:0072594 4 0.028
negative regulation of rna metabolic process GO:0051253 48 0.028
cell motility GO:0048870 244 0.028
regulation of multicellular organismal process GO:0051239 277 0.027
neuron development GO:0048666 262 0.027
regulation of macromolecule biosynthetic process GO:0010556 225 0.027
spliceosomal complex assembly GO:0000245 1 0.027
translational initiation GO:0006413 3 0.027
regulation of circadian rhythm GO:0042752 4 0.027
sensory organ development GO:0007423 393 0.027
cellular response to nutrient levels GO:0031669 2 0.025
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.025
behavior GO:0007610 74 0.025
transcription from rna polymerase ii promoter GO:0006366 80 0.025
phagocytosis GO:0006909 3 0.025
regulation of biosynthetic process GO:0009889 250 0.025
phosphorus metabolic process GO:0006793 109 0.024
oocyte maturation GO:0001556 4 0.024
regulation of signal transduction GO:0009966 225 0.024
regulation of nucleic acid templated transcription GO:1903506 213 0.024
fertilization GO:0009566 3 0.023
regulation of developmental process GO:0050793 247 0.023
positive regulation of cellular catabolic process GO:0031331 3 0.023
regulation of protein complex assembly GO:0043254 3 0.023
regulation of dendrite development GO:0050773 3 0.023
cellular component morphogenesis GO:0032989 336 0.023
gtp catabolic process GO:0006184 2 0.023
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.023
single organism localization GO:1902578 225 0.022
cell morphogenesis GO:0000902 289 0.022
cellular response to extracellular stimulus GO:0031668 2 0.022
protein import GO:0017038 3 0.022
regulation of protein catabolic process GO:0042176 1 0.022
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.022
positive regulation of transport GO:0051050 2 0.021
regulation of cell communication GO:0010646 232 0.021
eye development GO:0001654 277 0.021
muscle cell differentiation GO:0042692 139 0.020
positive regulation of cellular component biogenesis GO:0044089 3 0.020
regulation of multicellular organism growth GO:0040014 4 0.020
response to hexose GO:0009746 3 0.020
cell projection organization GO:0030030 284 0.020
negative regulation of cellular process GO:0048523 283 0.020
stem cell proliferation GO:0072089 4 0.020
cell part morphogenesis GO:0032990 246 0.020
nuclear import GO:0051170 3 0.020
wnt signaling pathway GO:0016055 80 0.020
neuron projection development GO:0031175 180 0.019
regulation of transcription dna templated GO:0006355 213 0.019
response to chemical GO:0042221 320 0.019
negative regulation of biological process GO:0048519 304 0.019
response to external stimulus GO:0009605 264 0.019
rna processing GO:0006396 25 0.018
purine nucleoside monophosphate catabolic process GO:0009128 4 0.018
response to ketone GO:1901654 1 0.018
amine metabolic process GO:0009308 2 0.018
g1 s transition of mitotic cell cycle GO:0000082 1 0.018
programmed cell death GO:0012501 119 0.018
mechanosensory behavior GO:0007638 2 0.018
dna templated transcription elongation GO:0006354 3 0.018
response to drug GO:0042493 3 0.018
meiotic nuclear division GO:0007126 4 0.018
positive regulation of gene expression GO:0010628 71 0.018
gtp metabolic process GO:0046039 4 0.018
stem cell maintenance GO:0019827 4 0.017
negative regulation of cellular metabolic process GO:0031324 77 0.017
regulation of protein transport GO:0051223 3 0.017
cell death GO:0008219 121 0.017
double strand break repair GO:0006302 3 0.017
regulation of protein import into nucleus GO:0042306 2 0.017
negative regulation of macromolecule metabolic process GO:0010605 76 0.017
regulation of establishment of protein localization GO:0070201 4 0.017
regulation of catalytic activity GO:0050790 55 0.017
growth GO:0040007 174 0.017
spermatid differentiation GO:0048515 2 0.017
cell projection morphogenesis GO:0048858 244 0.017
regulation of cellular protein catabolic process GO:1903362 1 0.017
negative regulation of developmental process GO:0051093 65 0.017
protein polymerization GO:0051258 4 0.017
multicellular organism growth GO:0035264 4 0.017
actin filament based process GO:0030029 64 0.017
response to glucose GO:0009749 3 0.017
regulation of cellular ketone metabolic process GO:0010565 7 0.017
gamete generation GO:0007276 33 0.016
blood vessel morphogenesis GO:0048514 216 0.016
regulation of postsynaptic membrane potential GO:0060078 1 0.016
single organism transport GO:0044765 206 0.016
regulation of signaling GO:0023051 235 0.016
cellular response to stress GO:0033554 62 0.016
protein metabolic process GO:0019538 183 0.016
negative regulation of mitosis GO:0045839 3 0.016
regulation of molecular function GO:0065009 70 0.016
regulation of reproductive process GO:2000241 4 0.016
phosphate containing compound metabolic process GO:0006796 108 0.016
negative regulation of dna metabolic process GO:0051053 4 0.016
response to wounding GO:0009611 116 0.016
cellular response to external stimulus GO:0071496 2 0.016
cellular response to starvation GO:0009267 1 0.015
regulation of cell shape GO:0008360 1 0.015
neuron projection morphogenesis GO:0048812 161 0.015
negative regulation of gene expression GO:0010629 65 0.015
regulation of nucleoside metabolic process GO:0009118 2 0.015
cell morphogenesis involved in differentiation GO:0000904 195 0.015
retina development in camera type eye GO:0060041 146 0.015
peptide transport GO:0015833 1 0.015
lateral inhibition GO:0046331 1 0.015
transport GO:0006810 220 0.015
rna localization GO:0006403 4 0.014
lamellipodium assembly GO:0030032 1 0.014
carbohydrate homeostasis GO:0033500 1 0.014
guanosine containing compound catabolic process GO:1901069 2 0.014
regulation of cellular component organization GO:0051128 86 0.014
camera type eye development GO:0043010 222 0.014
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 10 0.014
regulation of intracellular protein transport GO:0033157 3 0.014
female sex differentiation GO:0046660 4 0.014
chordate embryonic development GO:0043009 271 0.014
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.014
cellular macromolecular complex assembly GO:0034622 24 0.014
nuclear envelope organization GO:0006998 2 0.014
response to radiation GO:0009314 51 0.014
dna templated transcription initiation GO:0006352 1 0.014
cell cycle GO:0007049 93 0.014
vasculature development GO:0001944 278 0.014
small molecule metabolic process GO:0044281 77 0.014
developmental growth GO:0048589 166 0.014
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.014
negative regulation of kinase activity GO:0033673 4 0.014
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
intracellular receptor signaling pathway GO:0030522 30 0.013
sequestering of calcium ion GO:0051208 3 0.013
proteasomal protein catabolic process GO:0010498 2 0.013
regulation of synapse organization GO:0050807 3 0.013
membrane invagination GO:0010324 1 0.013
atp catabolic process GO:0006200 4 0.013
neuroblast proliferation GO:0007405 2 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.013
negative regulation of catabolic process GO:0009895 3 0.013
axon development GO:0061564 166 0.013
rhythmic process GO:0048511 21 0.013
negative regulation of chromatin modification GO:1903309 1 0.013
cellular component disassembly GO:0022411 1 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
actin polymerization or depolymerization GO:0008154 2 0.013
negative regulation of protein phosphorylation GO:0001933 4 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.013
negative chemotaxis GO:0050919 1 0.013
guanosine containing compound metabolic process GO:1901068 4 0.012
negative regulation of cellular catabolic process GO:0031330 3 0.012
ribonucleoside monophosphate catabolic process GO:0009158 4 0.012
lamellipodium organization GO:0097581 1 0.012
regulation of gene expression epigenetic GO:0040029 11 0.012
striated muscle cell differentiation GO:0051146 129 0.012
enzyme linked receptor protein signaling pathway GO:0007167 106 0.012
cellular amino acid metabolic process GO:0006520 7 0.012
reproductive process GO:0022414 40 0.012
lymphocyte proliferation GO:0046651 1 0.012
cellular localization GO:0051641 97 0.012
regulation of gtpase activity GO:0043087 2 0.012
positive regulation of macromolecule metabolic process GO:0010604 93 0.012
negative regulation of protein kinase activity GO:0006469 4 0.012
regulation of purine nucleotide catabolic process GO:0033121 2 0.012
regulation of stem cell differentiation GO:2000736 4 0.012
meiosis i GO:0007127 1 0.012
cytoskeleton dependent cytokinesis GO:0061640 3 0.012
positive regulation of apoptotic signaling pathway GO:2001235 1 0.012
positive regulation of cellular metabolic process GO:0031325 94 0.012
immune system development GO:0002520 191 0.012
regulation of growth rate GO:0040009 1 0.012
regulation of protein localization to nucleus GO:1900180 2 0.011
hematopoietic or lymphoid organ development GO:0048534 191 0.011
regulation of cell differentiation GO:0045595 142 0.011
homeostatic process GO:0042592 142 0.011
negative regulation of biosynthetic process GO:0009890 55 0.011
regulation of protein targeting GO:1903533 2 0.011
autophagy GO:0006914 4 0.011
erk1 and erk2 cascade GO:0070371 4 0.011
stem cell development GO:0048864 82 0.011
regulation of transcription from rna polymerase iii promoter GO:0006359 1 0.011
protein targeting to nucleus GO:0044744 3 0.011
internal protein amino acid acetylation GO:0006475 2 0.011
negative regulation of nucleic acid templated transcription GO:1903507 45 0.011
muscle structure development GO:0061061 196 0.011
actin cytoskeleton organization GO:0030036 63 0.011
internal peptidyl lysine acetylation GO:0018393 2 0.011
muscle organ development GO:0007517 101 0.011
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.011
modification dependent protein catabolic process GO:0019941 3 0.011
positive regulation of signal transduction GO:0009967 56 0.011
regulation of protein ubiquitination GO:0031396 3 0.011
rna 3 end processing GO:0031123 2 0.011
optic nerve morphogenesis GO:0021631 6 0.011
chromosome organization GO:0051276 31 0.011
regionalization GO:0003002 274 0.010
positive regulation of nucleotide catabolic process GO:0030813 1 0.010
protein import into nucleus GO:0006606 3 0.010
regulation of autophagy GO:0010506 3 0.010
somatic muscle development GO:0007525 4 0.010
mrna processing GO:0006397 14 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.010
cellular response to chemical stimulus GO:0070887 157 0.010
peptidyl threonine phosphorylation GO:0018107 1 0.010
synaptic growth at neuromuscular junction GO:0051124 2 0.010
nucleobase containing compound transport GO:0015931 2 0.010
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.010
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.010
development of primary female sexual characteristics GO:0046545 4 0.010
cellular ketone metabolic process GO:0042180 11 0.010
regulation of rna splicing GO:0043484 8 0.010
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.010

smek2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.014