Danio rerio

0 known processes

clica

chloride intracellular channel a

(Aliases: zgc:77835)

clica biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
hemopoiesis GO:0030097 183 0.092
larval development GO:0002164 2 0.091
response to external stimulus GO:0009605 264 0.083
lipid storage GO:0019915 1 0.081
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.080
cell morphogenesis GO:0000902 289 0.080
cellular protein catabolic process GO:0044257 4 0.078
positive regulation of transport GO:0051050 2 0.074
regulation of wound healing GO:0061041 2 0.070
modification dependent protein catabolic process GO:0019941 3 0.069
signal transduction GO:0007165 455 0.068
response to chemical GO:0042221 320 0.067
single organism localization GO:1902578 225 0.065
cell surface receptor signaling pathway GO:0007166 325 0.059
cellular response to chemical stimulus GO:0070887 157 0.056
maintenance of location GO:0051235 4 0.056
cell motility GO:0048870 244 0.055
heterocycle biosynthetic process GO:0018130 215 0.052
establishment of localization GO:0051234 244 0.052
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.050
digestive system development GO:0055123 289 0.050
cellular macromolecule metabolic process GO:0044260 391 0.050
regulation of establishment of protein localization GO:0070201 4 0.049
ubiquitin dependent protein catabolic process GO:0006511 3 0.048
organic cyclic compound biosynthetic process GO:1901362 223 0.048
positive regulation of biological process GO:0048518 253 0.047
heterocycle metabolic process GO:0046483 290 0.047
nitrogen compound metabolic process GO:0006807 319 0.046
hematopoietic or lymphoid organ development GO:0048534 191 0.045
response to stress GO:0006950 263 0.045
cellular biosynthetic process GO:0044249 286 0.045
cellular component morphogenesis GO:0032989 336 0.045
positive regulation of cellular process GO:0048522 201 0.044
immune system process GO:0002376 241 0.043
regulation of response to stimulus GO:0048583 269 0.043
nucleobase containing compound metabolic process GO:0006139 274 0.042
cell migration GO:0016477 237 0.042
cellular component movement GO:0006928 335 0.042
cellular response to xenobiotic stimulus GO:0071466 35 0.042
digestive tract morphogenesis GO:0048546 231 0.041
cellular nitrogen compound biosynthetic process GO:0044271 218 0.040
regulation of cell communication GO:0010646 232 0.040
regulation of protein transport GO:0051223 3 0.040
response to wounding GO:0009611 116 0.040
multicellular organism growth GO:0035264 4 0.039
neuron projection morphogenesis GO:0048812 161 0.039
phagocytosis GO:0006909 3 0.038
negative regulation of biological process GO:0048519 304 0.038
nucleobase containing compound biosynthetic process GO:0034654 205 0.038
regulation of macromolecule biosynthetic process GO:0010556 225 0.038
negative regulation of cellular process GO:0048523 283 0.038
regulation of protein complex assembly GO:0043254 3 0.037
growth GO:0040007 174 0.037
nucleic acid metabolic process GO:0090304 244 0.037
regulation of metabolic process GO:0019222 359 0.037
cellular macromolecule biosynthetic process GO:0034645 224 0.037
protein secretion GO:0009306 1 0.037
aromatic compound biosynthetic process GO:0019438 217 0.037
regulation of cytokine production GO:0001817 3 0.037
transport GO:0006810 220 0.036
developmental growth GO:0048589 166 0.036
locomotion GO:0040011 313 0.036
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.036
regulation of primary metabolic process GO:0080090 311 0.035
organic substance biosynthetic process GO:1901576 289 0.035
gastrulation GO:0007369 208 0.035
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.035
cellular nitrogen compound metabolic process GO:0034641 290 0.035
phagocytosis engulfment GO:0006911 1 0.034
convergent extension GO:0060026 118 0.033
positive regulation of cytokine production GO:0001819 2 0.033
gene expression GO:0010467 252 0.033
regulation of signal transduction GO:0009966 225 0.033
regulation of cellular metabolic process GO:0031323 320 0.032
positive regulation of cellular component biogenesis GO:0044089 3 0.032
cellular component disassembly GO:0022411 1 0.032
localization of cell GO:0051674 244 0.031
rna biosynthetic process GO:0032774 181 0.031
membrane lipid biosynthetic process GO:0046467 2 0.031
organic cyclic compound metabolic process GO:1901360 301 0.031
embryo development ending in birth or egg hatching GO:0009792 271 0.031
morphogenesis of an epithelium GO:0002009 333 0.030
single organism organelle organization GO:1902589 199 0.029
proteasomal protein catabolic process GO:0010498 2 0.029
single fertilization GO:0007338 3 0.029
stem cell maintenance GO:0019827 4 0.028
extrinsic apoptotic signaling pathway GO:0097191 3 0.028
aging GO:0007568 2 0.028
membrane invagination GO:0010324 1 0.027
regulation of multicellular organism growth GO:0040014 4 0.027
i kappab kinase nf kappab signaling GO:0007249 4 0.027
cell morphogenesis involved in differentiation GO:0000904 195 0.027
cellular aromatic compound metabolic process GO:0006725 295 0.027
exocytosis GO:0006887 1 0.027
sphingolipid biosynthetic process GO:0030148 2 0.027
regulation of biological quality GO:0065008 263 0.026
nuclear migration GO:0007097 3 0.026
cell projection organization GO:0030030 284 0.026
organic acid metabolic process GO:0006082 31 0.026
regulation of rna biosynthetic process GO:2001141 213 0.026
positive regulation of leukocyte mediated cytotoxicity GO:0001912 1 0.026
muscle structure development GO:0061061 196 0.026
multi organism process GO:0051704 134 0.025
interspecies interaction between organisms GO:0044419 4 0.025
regulation of gene expression GO:0010468 265 0.025
digestive tract development GO:0048565 265 0.025
cellular protein metabolic process GO:0044267 129 0.025
organelle organization GO:0006996 227 0.025
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.025
cellular amine metabolic process GO:0044106 2 0.024
response to drug GO:0042493 3 0.024
protein complex disassembly GO:0043241 1 0.024
negative regulation of mapk cascade GO:0043409 4 0.024
adult behavior GO:0030534 2 0.024
regulation of erk1 and erk2 cascade GO:0070372 4 0.024
convergent extension involved in gastrulation GO:0060027 71 0.024
protein polymerization GO:0051258 4 0.024
positive regulation of cell cycle GO:0045787 3 0.024
actin polymerization or depolymerization GO:0008154 2 0.023
regulation of rna metabolic process GO:0051252 224 0.023
modification dependent macromolecule catabolic process GO:0043632 3 0.023
mitochondrion organization GO:0007005 4 0.023
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.023
positive regulation of glucose transport GO:0010828 1 0.023
regulation of multicellular organismal development GO:2000026 223 0.023
tube morphogenesis GO:0035239 349 0.023
fatty acid elongation GO:0030497 1 0.023
system process GO:0003008 185 0.023
gtp metabolic process GO:0046039 4 0.023
amine metabolic process GO:0009308 2 0.023
response to external biotic stimulus GO:0043207 97 0.023
response to biotic stimulus GO:0009607 97 0.023
rna metabolic process GO:0016070 219 0.022
regulation of gtp catabolic process GO:0033124 2 0.022
cell part morphogenesis GO:0032990 246 0.022
regulation of intracellular protein transport GO:0033157 3 0.022
mesoderm development GO:0007498 88 0.022
meiotic nuclear division GO:0007126 4 0.022
positive regulation of immune effector process GO:0002699 3 0.022
cellular protein modification process GO:0006464 100 0.022
heart development GO:0007507 313 0.022
positive regulation of catabolic process GO:0009896 4 0.021
cognition GO:0050890 1 0.021
regulation of anatomical structure morphogenesis GO:0022603 130 0.021
response to other organism GO:0051707 97 0.021
biosynthetic process GO:0009058 294 0.021
sensory organ development GO:0007423 393 0.021
protein polyubiquitination GO:0000209 4 0.021
generation of neurons GO:0048699 385 0.021
fertilization GO:0009566 3 0.021
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.021
regulation of nucleotide catabolic process GO:0030811 2 0.020
regulation of nucleic acid templated transcription GO:1903506 213 0.020
multi organism cellular process GO:0044764 2 0.020
nucleic acid templated transcription GO:0097659 181 0.020
positive regulation of protein complex assembly GO:0031334 2 0.020
inner ear development GO:0048839 126 0.020
intracellular signal transduction GO:0035556 85 0.020
fatty acid biosynthetic process GO:0006633 4 0.020
camera type eye development GO:0043010 222 0.020
regulation of signaling GO:0023051 235 0.020
small molecule metabolic process GO:0044281 77 0.020
guanosine containing compound catabolic process GO:1901069 2 0.020
negative regulation of protein transport GO:0051224 3 0.020
rho protein signal transduction GO:0007266 5 0.020
autophagy GO:0006914 4 0.020
protein import GO:0017038 3 0.020
positive regulation of ras protein signal transduction GO:0046579 1 0.020
wound healing GO:0042060 90 0.020
protein modification process GO:0036211 100 0.020
regulation of cellular biosynthetic process GO:0031326 245 0.019
negative regulation of secretion by cell GO:1903531 2 0.019
cellular response to external stimulus GO:0071496 2 0.019
nucleocytoplasmic transport GO:0006913 4 0.019
cell projection morphogenesis GO:0048858 244 0.019
transcription dna templated GO:0006351 181 0.019
ras protein signal transduction GO:0007265 7 0.019
regulation of synaptic plasticity GO:0048167 1 0.019
regulation of response to biotic stimulus GO:0002831 2 0.019
establishment of organelle localization GO:0051656 45 0.019
glucose import GO:0046323 2 0.019
regulation of response to cytokine stimulus GO:0060759 3 0.019
negative regulation of response to stimulus GO:0048585 104 0.019
myeloid cell differentiation GO:0030099 86 0.019
regulation of nitrogen compound metabolic process GO:0051171 251 0.018
immune system development GO:0002520 191 0.018
regulation of nucleoside metabolic process GO:0009118 2 0.018
positive regulation of cytoskeleton organization GO:0051495 3 0.018
macromolecule biosynthetic process GO:0009059 227 0.018
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.018
establishment of protein localization to organelle GO:0072594 4 0.018
innate immune response GO:0045087 13 0.018
regulation of circadian rhythm GO:0042752 4 0.018
adherens junction maintenance GO:0034334 2 0.018
cytokinesis GO:0000910 3 0.018
regulation of protein localization to nucleus GO:1900180 2 0.018
negative regulation of signal transduction GO:0009968 94 0.018
guanosine containing compound metabolic process GO:1901068 4 0.017
single organism transport GO:0044765 206 0.017
cellular component assembly GO:0022607 170 0.017
cell proliferation GO:0008283 80 0.017
inositol lipid mediated signaling GO:0048017 2 0.017
negative regulation of nuclear division GO:0051784 3 0.017
positive regulation of cellular catabolic process GO:0031331 3 0.017
single organism metabolic process GO:0044710 217 0.017
blood vessel development GO:0001568 246 0.017
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.017
chordate embryonic development GO:0043009 271 0.017
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.017
regulation of protein import into nucleus GO:0042306 2 0.017
small gtpase mediated signal transduction GO:0007264 8 0.017
protein localization to nucleus GO:0034504 3 0.016
regulation of response to stress GO:0080134 36 0.016
actin filament polymerization GO:0030041 2 0.016
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.016
regulation of purine nucleotide catabolic process GO:0033121 2 0.016
germ line stem cell maintenance GO:0030718 2 0.016
regulation of apoptotic process GO:0042981 98 0.016
neuron development GO:0048666 262 0.016
golgi vesicle transport GO:0048193 3 0.016
stem cell division GO:0017145 1 0.016
meiotic cell cycle process GO:1903046 3 0.016
negative regulation of cell communication GO:0010648 96 0.016
mediolateral intercalation GO:0060031 3 0.016
regulation of transcription dna templated GO:0006355 213 0.016
carboxylic acid metabolic process GO:0019752 22 0.016
macromolecular complex disassembly GO:0032984 1 0.016
nuclear transport GO:0051169 4 0.016
transcription from rna polymerase ii promoter GO:0006366 80 0.016
neuron differentiation GO:0030182 353 0.016
regulation of protein polymerization GO:0032271 2 0.015
regulation of developmental process GO:0050793 247 0.015
regeneration GO:0031099 91 0.015
regulation of cytoplasmic transport GO:1903649 4 0.015
regulation of cellular ketone metabolic process GO:0010565 7 0.015
regulation of production of molecular mediator of immune response GO:0002700 1 0.015
ameboidal type cell migration GO:0001667 143 0.015
regulation of cell shape GO:0008360 1 0.015
regulation of cell death GO:0010941 103 0.015
positive regulation of cell activation GO:0050867 1 0.015
synaptic vesicle localization GO:0097479 1 0.015
regulation of biosynthetic process GO:0009889 250 0.015
regulation of receptor mediated endocytosis GO:0048259 4 0.015
death GO:0016265 121 0.015
regulation of multicellular organismal process GO:0051239 277 0.015
spindle assembly GO:0051225 2 0.015
regulation of programmed cell death GO:0043067 101 0.015
positive regulation of cell adhesion GO:0045785 1 0.015
protein metabolic process GO:0019538 183 0.015
positive regulation of wound healing GO:0090303 1 0.015
viral process GO:0016032 1 0.015
adherens junction organization GO:0034332 4 0.015
cellular component biogenesis GO:0044085 178 0.015
regulation of protein ubiquitination GO:0031396 3 0.015
defense response GO:0006952 47 0.015
regulation of cell differentiation GO:0045595 142 0.015
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.014
positive regulation of cellular metabolic process GO:0031325 94 0.014
cell migration involved in gastrulation GO:0042074 79 0.014
cellular response to extracellular stimulus GO:0031668 2 0.014
gtp catabolic process GO:0006184 2 0.014
cellular response to biotic stimulus GO:0071216 3 0.014
cellular response to molecule of bacterial origin GO:0071219 3 0.014
long chain fatty acid metabolic process GO:0001676 1 0.014
positive regulation of secretion GO:0051047 1 0.014
regulation of macromolecule metabolic process GO:0060255 317 0.014
protein targeting to nucleus GO:0044744 3 0.014
negative regulation of protein phosphorylation GO:0001933 4 0.014
vasculature development GO:0001944 278 0.014
positive regulation of metabolic process GO:0009893 108 0.014
positive regulation of multi organism process GO:0043902 3 0.014
homeostatic process GO:0042592 142 0.014
epithelial tube morphogenesis GO:0060562 148 0.014
wnt signaling pathway GO:0016055 80 0.014
regulation of binding GO:0051098 3 0.014
female sex differentiation GO:0046660 4 0.014
central nervous system development GO:0007417 387 0.014
regulation of cell motility GO:2000145 46 0.014
actin filament based process GO:0030029 64 0.014
fin regeneration GO:0031101 51 0.014
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.014
regulation of gtpase activity GO:0043087 2 0.014
cellular response to starvation GO:0009267 1 0.014
apoptotic process GO:0006915 116 0.013
regulation of nucleocytoplasmic transport GO:0046822 2 0.013
peptide transport GO:0015833 1 0.013
regulation of cell activation GO:0050865 1 0.013
neutrophil mediated immunity GO:0002446 1 0.013
cytoskeleton organization GO:0007010 96 0.013
cellular localization GO:0051641 97 0.013
phosphorus metabolic process GO:0006793 109 0.013
cellular component maintenance GO:0043954 3 0.013
regulation of protein complex disassembly GO:0043244 1 0.013
erk1 and erk2 cascade GO:0070371 4 0.013
response to bacterium GO:0009617 58 0.013
regulation of cellular amine metabolic process GO:0033238 0 0.013
organelle localization GO:0051640 49 0.013
regulation of tube size GO:0035150 2 0.013
regulation of blood coagulation GO:0030193 1 0.013
positive regulation of leukocyte mediated immunity GO:0002705 1 0.013
phosphatidylinositol mediated signaling GO:0048015 2 0.013
embryonic organ development GO:0048568 381 0.013
compound eye development GO:0048749 2 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
cellular response to organic substance GO:0071310 105 0.013
estrogen metabolic process GO:0008210 2 0.013
regulation of intracellular signal transduction GO:1902531 57 0.013
regulation of glucose transport GO:0010827 1 0.013
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.013
developmental growth involved in morphogenesis GO:0060560 86 0.013
regulation of rho protein signal transduction GO:0035023 2 0.013
regulation of locomotion GO:0040012 55 0.013
production of molecular mediator of immune response GO:0002440 2 0.012
phosphate containing compound metabolic process GO:0006796 108 0.012
cytoskeleton dependent cytokinesis GO:0061640 3 0.012
negative regulation of catabolic process GO:0009895 3 0.012
neuron projection development GO:0031175 180 0.012
positive regulation of exocytosis GO:0045921 1 0.012
spermatid differentiation GO:0048515 2 0.012
cellular response to lipopolysaccharide GO:0071222 3 0.012
negative regulation of mitosis GO:0045839 3 0.012
startle response GO:0001964 4 0.012
regulation of molecular function GO:0065009 70 0.012
organonitrogen compound metabolic process GO:1901564 74 0.012
chemosensory behavior GO:0007635 1 0.012
establishment of protein localization to plasma membrane GO:0090002 1 0.012
oxoacid metabolic process GO:0043436 31 0.012
axon development GO:0061564 166 0.012
negative regulation of stem cell differentiation GO:2000737 2 0.012
cell junction maintenance GO:0034331 2 0.012
negative regulation of response to cytokine stimulus GO:0060761 2 0.012
regulation of protein catabolic process GO:0042176 1 0.012
regulation of synapse assembly GO:0051963 3 0.012
gland development GO:0048732 143 0.012
regulation of mrna processing GO:0050684 3 0.012
organonitrogen compound biosynthetic process GO:1901566 47 0.012
negative regulation of signaling GO:0023057 96 0.012
neurological system process GO:0050877 62 0.012
skeletal system morphogenesis GO:0048705 102 0.012
cellular amino acid metabolic process GO:0006520 7 0.011
response to organic substance GO:0010033 153 0.011
response to vitamin GO:0033273 3 0.011
peptidyl serine phosphorylation GO:0018105 1 0.011
positive regulation of macromolecule metabolic process GO:0010604 93 0.011
negative regulation of secretion GO:0051048 2 0.011
membrane fusion GO:0061025 2 0.011
regulation of autophagy GO:0010506 3 0.011
response to xenobiotic stimulus GO:0009410 45 0.011
embryonic skeletal system morphogenesis GO:0048704 93 0.011
positive regulation of secretion by cell GO:1903532 1 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
regulation of microtubule cytoskeleton organization GO:0070507 3 0.011
positive regulation of glucose import GO:0046326 1 0.011
embryonic organ morphogenesis GO:0048562 274 0.011
negative regulation of kinase activity GO:0033673 4 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.011
positive regulation of stress activated mapk cascade GO:0032874 3 0.011
protein import into nucleus GO:0006606 3 0.011
protein complex localization GO:0031503 1 0.011
regulation of protein targeting GO:1903533 2 0.011
response to virus GO:0009615 21 0.011
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.011
regulation of reproductive process GO:2000241 4 0.011
programmed cell death GO:0012501 119 0.011
internal peptidyl lysine acetylation GO:0018393 2 0.011
regionalization GO:0003002 274 0.011
negative regulation of protein kinase activity GO:0006469 4 0.011
peptidyl serine modification GO:0018209 2 0.011
single organism nuclear import GO:1902593 3 0.011
tube closure GO:0060606 1 0.011
lateral inhibition GO:0046331 1 0.011
regulation of glucose import GO:0046324 1 0.010
cellular component assembly involved in morphogenesis GO:0010927 107 0.010
regulation of inflammatory response GO:0050727 2 0.010
positive regulation of cellular amine metabolic process GO:0033240 0 0.010
melanosome transport GO:0032402 19 0.010
embryonic heart tube development GO:0035050 133 0.010
tissue regeneration GO:0042246 74 0.010
cell killing GO:0001906 2 0.010
positive regulation of nucleotide catabolic process GO:0030813 1 0.010
regulation of metal ion transport GO:0010959 4 0.010
axis specification GO:0009798 43 0.010
positive regulation of chromosome organization GO:2001252 1 0.010
neuroblast proliferation GO:0007405 2 0.010
regulation of wnt signaling pathway GO:0030111 53 0.010
stem cell proliferation GO:0072089 4 0.010
regulation of establishment of planar polarity GO:0090175 4 0.010
positive regulation of signal transduction GO:0009967 56 0.010
leukocyte proliferation GO:0070661 1 0.010
negative regulation of cellular catabolic process GO:0031330 3 0.010
nuclear export GO:0051168 1 0.010
organic substance transport GO:0071702 58 0.010
regulation of stem cell differentiation GO:2000736 4 0.010
negative regulation of multi organism process GO:0043901 3 0.010
developmental maturation GO:0021700 34 0.010

clica disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.034
nervous system disease DOID:863 0 0.025
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
organ system cancer DOID:0050686 0 0.014
disease of metabolism DOID:0014667 0 0.010