Danio rerio

14 known processes

pttg1ipb

pituitary tumor-transforming 1 interacting protein b

(Aliases: pttg1ip,zgc:103708)

pttg1ipb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
aging GO:0007568 2 0.097
maintenance of location GO:0051235 4 0.070
digestive tract morphogenesis GO:0048546 231 0.060
positive regulation of transport GO:0051050 2 0.048
cellular macromolecule metabolic process GO:0044260 391 0.046
determination of left right symmetry GO:0007368 179 0.041
regulation of cell communication GO:0010646 232 0.039
lipid storage GO:0019915 1 0.038
regulation of signal transduction GO:0009966 225 0.036
signal transduction GO:0007165 455 0.035
regulation of macromolecule metabolic process GO:0060255 317 0.034
response to stress GO:0006950 263 0.034
alcohol biosynthetic process GO:0046165 2 0.032
catechol containing compound metabolic process GO:0009712 2 0.031
response to zinc ion GO:0010043 6 0.030
regulation of gene expression GO:0010468 265 0.029
negative regulation of kinase activity GO:0033673 4 0.029
regulation of ph GO:0006885 3 0.029
cell surface receptor signaling pathway GO:0007166 325 0.026
gene expression GO:0010467 252 0.026
sensory organ development GO:0007423 393 0.025
autophagy GO:0006914 4 0.025
guanosine containing compound metabolic process GO:1901068 4 0.024
zinc ion transport GO:0006829 2 0.024
cellular aldehyde metabolic process GO:0006081 4 0.024
negative regulation of protein phosphorylation GO:0001933 4 0.023
negative regulation of protein kinase activity GO:0006469 4 0.023
negative regulation of cytokine production GO:0001818 1 0.023
regulation of cytokine production GO:0001817 3 0.022
cellular response to external stimulus GO:0071496 2 0.022
erk1 and erk2 cascade GO:0070371 4 0.022
regulation of neurotransmitter transport GO:0051588 1 0.022
regulation of stem cell differentiation GO:2000736 4 0.022
synaptic vesicle localization GO:0097479 1 0.022
establishment of synaptic vesicle localization GO:0097480 1 0.022
synaptic vesicle endocytosis GO:0048488 1 0.021
extrinsic apoptotic signaling pathway GO:0097191 3 0.021
ethanol metabolic process GO:0006067 1 0.021
regulation of neural precursor cell proliferation GO:2000177 3 0.021
regulation of synaptic plasticity GO:0048167 1 0.021
organelle organization GO:0006996 227 0.021
cellular amine metabolic process GO:0044106 2 0.021
digestive system development GO:0055123 289 0.021
regulation of skeletal muscle tissue development GO:0048641 4 0.021
tube morphogenesis GO:0035239 349 0.021
cellular respiration GO:0045333 3 0.021
cell cycle arrest GO:0007050 1 0.021
apical junction assembly GO:0043297 1 0.020
negative regulation of biological process GO:0048519 304 0.020
response to alkaloid GO:0043279 2 0.020
macromolecule biosynthetic process GO:0009059 227 0.020
neurotransmitter transport GO:0006836 2 0.020
regulation of cell activation GO:0050865 1 0.019
fat soluble vitamin metabolic process GO:0006775 4 0.019
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.019
synaptic vesicle transport GO:0048489 1 0.019
negative regulation of signal transduction GO:0009968 94 0.019
negative regulation of cell communication GO:0010648 96 0.019
monoamine transport GO:0015844 1 0.018
positive regulation of secretion GO:0051047 1 0.018
positive regulation of catabolic process GO:0009896 4 0.018
adult behavior GO:0030534 2 0.018
regulation of cell killing GO:0031341 2 0.018
regulation of neurotransmitter secretion GO:0046928 1 0.017
neurotransmitter secretion GO:0007269 2 0.017
membrane invagination GO:0010324 1 0.017
organic substance biosynthetic process GO:1901576 289 0.017
carboxylic acid metabolic process GO:0019752 22 0.017
cell cycle g1 s phase transition GO:0044843 1 0.017
protein targeting to nucleus GO:0044744 3 0.016
Human
regulation of neuronal synaptic plasticity GO:0048168 1 0.016
response to other organism GO:0051707 97 0.016
i kappab kinase nf kappab signaling GO:0007249 4 0.016
leukocyte proliferation GO:0070661 1 0.016
regulation of response to stimulus GO:0048583 269 0.016
lateral inhibition GO:0046331 1 0.016
pyruvate metabolic process GO:0006090 1 0.016
heterocycle metabolic process GO:0046483 290 0.016
negative regulation of sequestering of calcium ion GO:0051283 4 0.016
cellular protein metabolic process GO:0044267 129 0.016
cellular amino acid biosynthetic process GO:0008652 2 0.016
meiotic nuclear division GO:0007126 4 0.016
negative regulation of signaling GO:0023057 96 0.016
phagocytosis GO:0006909 3 0.015
regulation of metabolic process GO:0019222 359 0.015
positive regulation of leukocyte differentiation GO:1902107 1 0.015
response to wounding GO:0009611 116 0.015
larval development GO:0002164 2 0.015
alpha amino acid metabolic process GO:1901605 3 0.015
lymphocyte proliferation GO:0046651 1 0.015
dopamine biosynthetic process GO:0042416 2 0.015
regulation of signaling GO:0023051 235 0.015
response to hydrogen peroxide GO:0042542 3 0.015
nucleocytoplasmic transport GO:0006913 4 0.015
Human
response to uv GO:0009411 3 0.015
nuclear import GO:0051170 3 0.015
Human
epithelial tube morphogenesis GO:0060562 148 0.015
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.015
regulation of biological quality GO:0065008 263 0.015
response to glucocorticoid GO:0051384 1 0.015
specification of symmetry GO:0009799 204 0.015
regulation of apoptotic process GO:0042981 98 0.015
pancreas development GO:0031016 84 0.015
regulation of jun kinase activity GO:0043506 3 0.014
regulation of biosynthetic process GO:0009889 250 0.014
programmed cell death GO:0012501 119 0.014
negative regulation of intracellular transport GO:0032387 3 0.014
negative regulation of cytoplasmic transport GO:1903650 2 0.014
toxin metabolic process GO:0009404 1 0.014
zinc ion homeostasis GO:0055069 1 0.014
gtp metabolic process GO:0046039 4 0.014
secondary metabolic process GO:0019748 3 0.014
catechol containing compound biosynthetic process GO:0009713 2 0.014
camera type eye development GO:0043010 222 0.014
axon ensheathment in central nervous system GO:0032291 2 0.014
regulation of programmed cell death GO:0043067 101 0.014
regulation of cytoplasmic transport GO:1903649 4 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.014
positive regulation of cell activation GO:0050867 1 0.014
positive regulation of secretion by cell GO:1903532 1 0.013
protein metabolic process GO:0019538 183 0.013
system process GO:0003008 185 0.013
regulation of intracellular signal transduction GO:1902531 57 0.013
b cell differentiation GO:0030183 1 0.013
regulation of epithelial cell proliferation GO:0050678 3 0.013
mitotic dna damage checkpoint GO:0044773 4 0.013
cellular protein catabolic process GO:0044257 4 0.013
regulation of multicellular organism growth GO:0040014 4 0.013
dopamine metabolic process GO:0042417 2 0.013
protein import into nucleus GO:0006606 3 0.013
Human
mitochondrion organization GO:0007005 4 0.013
p38mapk cascade GO:0038066 1 0.013
retina development in camera type eye GO:0060041 146 0.013
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.013
cellular nitrogen compound metabolic process GO:0034641 290 0.013
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.013
transmission of nerve impulse GO:0019226 19 0.013
cilium assembly GO:0042384 58 0.013
cell death GO:0008219 121 0.013
notochord development GO:0030903 54 0.013
cellular amino acid metabolic process GO:0006520 7 0.013
digestive tract development GO:0048565 265 0.013
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.013
hepaticobiliary system development GO:0061008 98 0.013
negative regulation of response to stimulus GO:0048585 104 0.013
embryonic organ development GO:0048568 381 0.012
response to nutrient GO:0007584 3 0.012
gland development GO:0048732 143 0.012
protein polyubiquitination GO:0000209 4 0.012
tissue remodeling GO:0048771 4 0.012
regulation of metal ion transport GO:0010959 4 0.012
cilium organization GO:0044782 71 0.012
gtp catabolic process GO:0006184 2 0.012
urogenital system development GO:0001655 97 0.012
tyrosine metabolic process GO:0006570 1 0.012
indole containing compound metabolic process GO:0042430 2 0.012
mitotic dna integrity checkpoint GO:0044774 4 0.012
proteasomal protein catabolic process GO:0010498 2 0.012
phagosome maturation GO:0090382 1 0.012
neuroblast proliferation GO:0007405 2 0.012
response to organic substance GO:0010033 153 0.012
regulation of cellular ph GO:0030641 1 0.012
negative regulation of ras protein signal transduction GO:0046580 1 0.012
sensory perception of smell GO:0007608 2 0.012
regulation of reproductive process GO:2000241 4 0.012
ph reduction GO:0045851 1 0.012
positive regulation of cell cycle GO:0045787 3 0.012
catecholamine metabolic process GO:0006584 2 0.012
mononuclear cell proliferation GO:0032943 1 0.012
regulation of carbohydrate metabolic process GO:0006109 4 0.011
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.011
locomotor rhythm GO:0045475 3 0.011
heart morphogenesis GO:0003007 156 0.011
biosynthetic process GO:0009058 294 0.011
response to drug GO:0042493 3 0.011
amine metabolic process GO:0009308 2 0.011
nucleic acid templated transcription GO:0097659 181 0.011
regulation of intracellular ph GO:0051453 1 0.011
negative regulation of epithelial cell proliferation GO:0050680 1 0.011
cellular response to lipopolysaccharide GO:0071222 3 0.011
protein stabilization GO:0050821 2 0.011
regulation of p38mapk cascade GO:1900744 1 0.011
intracellular signal transduction GO:0035556 85 0.011
embryonic organ morphogenesis GO:0048562 274 0.011
cellular modified amino acid metabolic process GO:0006575 3 0.011
regulation of heart growth GO:0060420 2 0.011
regulation of blood pressure GO:0008217 1 0.011
entrainment of circadian clock by photoperiod GO:0043153 1 0.011
organelle assembly GO:0070925 110 0.011
photoreceptor cell fate commitment GO:0046552 1 0.011
establishment of rna localization GO:0051236 3 0.011
stem cell division GO:0017145 1 0.011
oxoacid metabolic process GO:0043436 31 0.011
establishment of protein localization to organelle GO:0072594 4 0.011
Human
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.011
response to cadmium ion GO:0046686 14 0.011
cellular response to biotic stimulus GO:0071216 3 0.011
central nervous system development GO:0007417 387 0.011
stem cell proliferation GO:0072089 4 0.011
response to vitamin GO:0033273 3 0.011
signal transduction in absence of ligand GO:0038034 1 0.011
nucleic acid transport GO:0050657 2 0.011
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.011
neuronal action potential GO:0019228 18 0.011
positive regulation of carbohydrate metabolic process GO:0045913 1 0.011
thermosensory behavior GO:0040040 1 0.011
rna biosynthetic process GO:0032774 181 0.010
determination of bilateral symmetry GO:0009855 204 0.010
response to abiotic stimulus GO:0009628 122 0.010
organic acid metabolic process GO:0006082 31 0.010
regulation of fatty acid metabolic process GO:0019217 1 0.010
chemosensory behavior GO:0007635 1 0.010
nucleic acid metabolic process GO:0090304 244 0.010
regulation of epithelial to mesenchymal transition GO:0010717 3 0.010
spermatid development GO:0007286 2 0.010
nephron epithelium morphogenesis GO:0072088 1 0.010
spermatid differentiation GO:0048515 2 0.010
vacuolar transport GO:0007034 2 0.010
hormone biosynthetic process GO:0042446 3 0.010
release of sequestered calcium ion into cytosol GO:0051209 3 0.010
g1 s transition of mitotic cell cycle GO:0000082 1 0.010
catecholamine biosynthetic process GO:0042423 2 0.010

pttg1ipb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
lysosomal storage disease DOID:3211 0 0.036
disease of metabolism DOID:0014667 0 0.036
inherited metabolic disorder DOID:655 0 0.036
disease of anatomical entity DOID:7 0 0.014
nervous system disease DOID:863 0 0.013
sensory system disease DOID:0050155 0 0.012
eye and adnexa disease DOID:1492 0 0.012
eye disease DOID:5614 0 0.012
charcot marie tooth disease DOID:10595 0 0.010
neuromuscular disease DOID:440 0 0.010
neuropathy DOID:870 0 0.010