Danio rerio

0 known processes

ube2d2

ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)

(Aliases: zgc:73200,wu:fj13d01)

ube2d2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.339
cellular macromolecule metabolic process GO:0044260 391 0.207
Yeast
modification dependent protein catabolic process GO:0019941 3 0.186
Yeast
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.179
Yeast
cellular protein catabolic process GO:0044257 4 0.160
Yeast
regulation of cellular biosynthetic process GO:0031326 245 0.145
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.139
aging GO:0007568 2 0.136
ubiquitin dependent protein catabolic process GO:0006511 3 0.135
Yeast
cellular macromolecule biosynthetic process GO:0034645 224 0.117
modification dependent macromolecule catabolic process GO:0043632 3 0.115
Yeast
regulation of metabolic process GO:0019222 359 0.107
nitrogen compound metabolic process GO:0006807 319 0.104
regulation of gene expression GO:0010468 265 0.103
protein metabolic process GO:0019538 183 0.100
Yeast
nucleobase containing compound biosynthetic process GO:0034654 205 0.092
regulation of macromolecule metabolic process GO:0060255 317 0.092
organic cyclic compound metabolic process GO:1901360 301 0.083
cellular nitrogen compound biosynthetic process GO:0044271 218 0.083
cellular nitrogen compound metabolic process GO:0034641 290 0.083
mitochondrion organization GO:0007005 4 0.070
organic cyclic compound biosynthetic process GO:1901362 223 0.070
nucleobase containing compound metabolic process GO:0006139 274 0.068
rna biosynthetic process GO:0032774 181 0.068
aromatic compound biosynthetic process GO:0019438 217 0.067
embryo development ending in birth or egg hatching GO:0009792 271 0.066
transcription dna templated GO:0006351 181 0.066
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.066
regulation of macromolecule biosynthetic process GO:0010556 225 0.065
nucleic acid metabolic process GO:0090304 244 0.062
heterocycle biosynthetic process GO:0018130 215 0.062
microtubule organizing center organization GO:0031023 1 0.060
signal transduction GO:0007165 455 0.060
cellular component movement GO:0006928 335 0.059
positive regulation of catabolic process GO:0009896 4 0.059
proteasomal protein catabolic process GO:0010498 2 0.058
regulation of biosynthetic process GO:0009889 250 0.057
protein polyubiquitination GO:0000209 4 0.055
Yeast
regulation of nitrogen compound metabolic process GO:0051171 251 0.055
response to chemical GO:0042221 320 0.055
neuron development GO:0048666 262 0.053
establishment of localization GO:0051234 244 0.053
regulation of protein ubiquitination GO:0031396 3 0.053
heterocycle metabolic process GO:0046483 290 0.051
positive regulation of transport GO:0051050 2 0.051
regulation of response to stimulus GO:0048583 269 0.050
regulation of primary metabolic process GO:0080090 311 0.050
single fertilization GO:0007338 3 0.050
meiotic cell cycle process GO:1903046 3 0.048
regulation of nucleic acid templated transcription GO:1903506 213 0.047
cell cycle g1 s phase transition GO:0044843 1 0.047
gene expression GO:0010467 252 0.047
mitotic dna integrity checkpoint GO:0044774 4 0.046
mitotic dna damage checkpoint GO:0044773 4 0.046
centrosome cycle GO:0007098 1 0.045
regulation of rna metabolic process GO:0051252 224 0.044
regulation of signal transduction GO:0009966 225 0.044
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.043
macromolecule biosynthetic process GO:0009059 227 0.043
meiotic nuclear division GO:0007126 4 0.043
transport GO:0006810 220 0.042
negative regulation of biological process GO:0048519 304 0.042
regulation of transcription dna templated GO:0006355 213 0.041
protein modification by small protein conjugation or removal GO:0070647 14 0.040
Yeast
regulation of protein complex assembly GO:0043254 3 0.040
nucleic acid templated transcription GO:0097659 181 0.040
macromolecule modification GO:0043412 111 0.039
Yeast
cellular biosynthetic process GO:0044249 286 0.039
positive regulation of cellular catabolic process GO:0031331 3 0.039
protein localization to plasma membrane GO:0072659 1 0.039
rna metabolic process GO:0016070 219 0.038
biosynthetic process GO:0009058 294 0.038
cellular protein metabolic process GO:0044267 129 0.038
Yeast
protein modification process GO:0036211 100 0.037
Yeast
regulation of establishment of protein localization GO:0070201 4 0.037
cellular component morphogenesis GO:0032989 336 0.037
regulation of signaling GO:0023051 235 0.037
cellular aromatic compound metabolic process GO:0006725 295 0.035
protein dephosphorylation GO:0006470 3 0.035
centrosome organization GO:0051297 1 0.035
regulation of rna biosynthetic process GO:2001141 213 0.035
locomotion GO:0040011 313 0.035
cellular protein modification process GO:0006464 100 0.034
Yeast
regulation of protein targeting GO:1903533 2 0.034
response to stress GO:0006950 263 0.033
Yeast
phosphate containing compound metabolic process GO:0006796 108 0.033
neuron differentiation GO:0030182 353 0.033
peptidyl serine phosphorylation GO:0018105 1 0.033
synaptic vesicle localization GO:0097479 1 0.033
positive regulation of cell cycle GO:0045787 3 0.033
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.033
protein k48 linked ubiquitination GO:0070936 1 0.033
cell part morphogenesis GO:0032990 246 0.032
negative regulation of response to stimulus GO:0048585 104 0.032
cellular component disassembly GO:0022411 1 0.032
cellular response to chemical stimulus GO:0070887 157 0.031
stem cell proliferation GO:0072089 4 0.031
generation of neurons GO:0048699 385 0.031
regulation of nucleocytoplasmic transport GO:0046822 2 0.030
establishment of protein localization to organelle GO:0072594 4 0.030
amine metabolic process GO:0009308 2 0.030
regulation of cytoplasmic transport GO:1903649 4 0.030
membrane fusion GO:0061025 2 0.030
system process GO:0003008 185 0.030
cellular amine metabolic process GO:0044106 2 0.029
meiosis i GO:0007127 1 0.029
positive regulation of nucleoside metabolic process GO:0045979 1 0.029
negative regulation of cell communication GO:0010648 96 0.029
apoptotic signaling pathway GO:0097190 23 0.029
cortical actin cytoskeleton organization GO:0030866 1 0.029
cell surface receptor signaling pathway GO:0007166 325 0.029
cellular carbohydrate metabolic process GO:0044262 4 0.028
organism emergence from protective structure GO:0071684 4 0.028
death GO:0016265 121 0.028
negative regulation of cellular process GO:0048523 283 0.028
cell death GO:0008219 121 0.028
chromatin modification GO:0016568 21 0.028
single organism organelle organization GO:1902589 199 0.027
immune system process GO:0002376 241 0.027
programmed cell death GO:0012501 119 0.027
establishment of protein localization to plasma membrane GO:0090002 1 0.027
multi organism process GO:0051704 134 0.027
cell migration GO:0016477 237 0.027
single organism metabolic process GO:0044710 217 0.027
protein targeting to nucleus GO:0044744 3 0.027
regulation of protein catabolic process GO:0042176 1 0.027
response to glucose GO:0009749 3 0.027
fertilization GO:0009566 3 0.026
g2 dna damage checkpoint GO:0031572 3 0.026
protein import GO:0017038 3 0.026
cell projection morphogenesis GO:0048858 244 0.026
cytokinesis GO:0000910 3 0.026
stem cell division GO:0017145 1 0.025
protein import into nucleus GO:0006606 3 0.025
carboxylic acid metabolic process GO:0019752 22 0.025
maintenance of location GO:0051235 4 0.025
g1 s transition of mitotic cell cycle GO:0000082 1 0.025
protein stabilization GO:0050821 2 0.025
organic substance biosynthetic process GO:1901576 289 0.025
nuclear import GO:0051170 3 0.025
adult behavior GO:0030534 2 0.025
regulation of cell communication GO:0010646 232 0.024
organelle fusion GO:0048284 3 0.024
cellular macromolecule catabolic process GO:0044265 12 0.024
Yeast
sensory organ development GO:0007423 393 0.024
oxoacid metabolic process GO:0043436 31 0.024
single organism nuclear import GO:1902593 3 0.024
cell morphogenesis involved in differentiation GO:0000904 195 0.024
regulation of intracellular protein transport GO:0033157 3 0.023
positive regulation of biological process GO:0048518 253 0.023
mitotic g2 m transition checkpoint GO:0044818 3 0.023
regulation of cellular ketone metabolic process GO:0010565 7 0.023
regulation of nucleoside metabolic process GO:0009118 2 0.023
response to drug GO:0042493 3 0.023
regulation of cellular amine metabolic process GO:0033238 0 0.023
cellular amino acid metabolic process GO:0006520 7 0.023
regulation of cellular metabolic process GO:0031323 320 0.023
neuroblast proliferation GO:0007405 2 0.023
gtp metabolic process GO:0046039 4 0.023
response to organic substance GO:0010033 153 0.023
regulation of apoptotic process GO:0042981 98 0.022
nuclear transport GO:0051169 4 0.022
regulation of cell shape GO:0008360 1 0.022
cognition GO:0050890 1 0.022
nucleocytoplasmic transport GO:0006913 4 0.022
apoptotic process GO:0006915 116 0.022
regulation of cell death GO:0010941 103 0.022
lipid storage GO:0019915 1 0.021
single organism membrane fusion GO:0044801 2 0.021
regulation of protein transport GO:0051223 3 0.021
axonogenesis GO:0007409 152 0.021
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.021
regulation of cytokine production GO:0001817 3 0.021
peptide transport GO:0015833 1 0.021
synaptic growth at neuromuscular junction GO:0051124 2 0.021
organelle organization GO:0006996 227 0.021
double strand break repair via homologous recombination GO:0000724 1 0.021
negative regulation of cytoplasmic transport GO:1903650 2 0.021
guanosine containing compound catabolic process GO:1901069 2 0.021
recombinational repair GO:0000725 1 0.021
homeostatic process GO:0042592 142 0.020
regulation of nucleotide catabolic process GO:0030811 2 0.020
regulation of biological quality GO:0065008 263 0.020
cell morphogenesis GO:0000902 289 0.020
multicellular organism growth GO:0035264 4 0.020
regulation of binding GO:0051098 3 0.020
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
regulation of protein import into nucleus GO:0042306 2 0.020
regulation of apoptotic signaling pathway GO:2001233 12 0.019
regulation of carbohydrate metabolic process GO:0006109 4 0.019
negative regulation of protein phosphorylation GO:0001933 4 0.019
regulation of purine nucleotide catabolic process GO:0033121 2 0.019
hormone secretion GO:0046879 2 0.019
protein localization to nucleus GO:0034504 3 0.019
regulation of synapse organization GO:0050807 3 0.019
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.019
regulation of cellular protein catabolic process GO:1903362 1 0.019
negative regulation of metabolic process GO:0009892 86 0.019
regulation of cell activation GO:0050865 1 0.019
positive regulation of cellular component biogenesis GO:0044089 3 0.019
cell motility GO:0048870 244 0.019
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.019
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.018
single organism localization GO:1902578 225 0.018
i kappab kinase nf kappab signaling GO:0007249 4 0.018
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.018
lateral inhibition GO:0046331 1 0.018
mrna stabilization GO:0048255 4 0.018
protein polymerization GO:0051258 4 0.018
cortical cytoskeleton organization GO:0030865 1 0.018
gtp catabolic process GO:0006184 2 0.018
peptidyl serine modification GO:0018209 2 0.018
autophagy GO:0006914 4 0.018
positive regulation of chromosome organization GO:2001252 1 0.018
mitotic g2 dna damage checkpoint GO:0007095 3 0.018
macromolecule catabolic process GO:0009057 15 0.018
Yeast
developmental growth GO:0048589 166 0.018
positive regulation of histone modification GO:0031058 1 0.018
regulation of developmental process GO:0050793 247 0.018
positive regulation of secretion GO:0051047 1 0.017
response to external stimulus GO:0009605 264 0.017
extrinsic apoptotic signaling pathway GO:0097191 3 0.017
cellular response to organic substance GO:0071310 105 0.017
histone modification GO:0016570 20 0.017
localization of cell GO:0051674 244 0.017
mitotic cell cycle embryonic GO:0045448 2 0.017
organonitrogen compound metabolic process GO:1901564 74 0.017
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.017
cell projection organization GO:0030030 284 0.017
guanosine containing compound metabolic process GO:1901068 4 0.017
organic acid metabolic process GO:0006082 31 0.017
cellular component assembly GO:0022607 170 0.017
positive regulation of nucleotide catabolic process GO:0030813 1 0.016
exocytosis GO:0006887 1 0.016
regulation of cellular protein metabolic process GO:0032268 52 0.016
b cell activation GO:0042113 2 0.016
positive regulation of secretion by cell GO:1903532 1 0.016
positive regulation of apoptotic signaling pathway GO:2001235 1 0.016
spindle assembly GO:0051225 2 0.016
cellular response to external stimulus GO:0071496 2 0.016
central nervous system development GO:0007417 387 0.016
positive regulation of chromatin modification GO:1903310 1 0.016
response to carbohydrate GO:0009743 3 0.016
positive regulation of protein complex assembly GO:0031334 2 0.016
chordate embryonic development GO:0043009 271 0.016
pronuclear migration GO:0035046 1 0.016
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.016
negative regulation of protein complex assembly GO:0031333 1 0.015
positive regulation of dna metabolic process GO:0051054 1 0.015
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.015
chemosensory behavior GO:0007635 1 0.015
taxis GO:0042330 109 0.015
ameboidal type cell migration GO:0001667 143 0.015
double strand break repair GO:0006302 3 0.015
response to monosaccharide GO:0034284 3 0.015
negative regulation of signal transduction GO:0009968 94 0.015
blood vessel development GO:0001568 246 0.015
protein modification by small protein conjugation GO:0032446 13 0.015
Yeast
regulation of exocytosis GO:0017157 1 0.015
regulation of intracellular signal transduction GO:1902531 57 0.015
cytoskeleton dependent cytokinesis GO:0061640 3 0.015
digestive tract development GO:0048565 265 0.015
response to hexose GO:0009746 3 0.015
negative regulation of synapse assembly GO:0051964 2 0.015
positive regulation of metabolic process GO:0009893 108 0.015
negative regulation of macromolecule metabolic process GO:0010605 76 0.015
phagocytosis GO:0006909 3 0.015
macromolecular complex disassembly GO:0032984 1 0.015
regulation of localization GO:0032879 104 0.015
intracellular signal transduction GO:0035556 85 0.015
negative regulation of transcription dna templated GO:0045892 45 0.015
negative regulation of cell death GO:0060548 60 0.015
negative regulation of protein transport GO:0051224 3 0.014
hormone transport GO:0009914 2 0.014
positive regulation of cellular process GO:0048522 201 0.014
actin polymerization or depolymerization GO:0008154 2 0.014
covalent chromatin modification GO:0016569 20 0.014
sequestering of metal ion GO:0051238 3 0.014
cellular ketone metabolic process GO:0042180 11 0.014
regulation of multicellular organism growth GO:0040014 4 0.014
regulation of cell cycle GO:0051726 52 0.014
regulation of protein localization to nucleus GO:1900180 2 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.014
female sex differentiation GO:0046660 4 0.014
regulation of multicellular organismal process GO:0051239 277 0.014
morphogenesis of an epithelium GO:0002009 333 0.014
interspecies interaction between organisms GO:0044419 4 0.014
transcription from rna polymerase ii promoter GO:0006366 80 0.014
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.014
mitotic cell cycle GO:0000278 64 0.014
cellular response to nutrient levels GO:0031669 2 0.014
response to wounding GO:0009611 116 0.014
compound eye development GO:0048749 2 0.014
response to abiotic stimulus GO:0009628 122 0.014
Yeast
regulation of reproductive process GO:2000241 4 0.014
negative regulation of gene expression GO:0010629 65 0.014
dna biosynthetic process GO:0071897 3 0.014
peptidyl lysine acetylation GO:0018394 2 0.014
protein complex disassembly GO:0043241 1 0.014
negative regulation of apoptotic process GO:0043066 55 0.014
posttranscriptional regulation of gene expression GO:0010608 14 0.014
dorsal ventral pattern formation GO:0009953 125 0.014
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.014
golgi vesicle transport GO:0048193 3 0.014
glucose homeostasis GO:0042593 1 0.014
negative regulation of nuclear division GO:0051784 3 0.013
neuron projection morphogenesis GO:0048812 161 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
tube morphogenesis GO:0035239 349 0.013
regulation of chromosome segregation GO:0051983 1 0.013
behavior GO:0007610 74 0.013
synaptic vesicle transport GO:0048489 1 0.013
carbohydrate homeostasis GO:0033500 1 0.013
establishment of synaptic vesicle localization GO:0097480 1 0.013
negative regulation of programmed cell death GO:0043069 58 0.013
regulation of molecular function GO:0065009 70 0.013
carbohydrate biosynthetic process GO:0016051 1 0.013
muscle organ development GO:0007517 101 0.013
digestive system development GO:0055123 289 0.013
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.013
nucleoside monophosphate catabolic process GO:0009125 4 0.013
small molecule metabolic process GO:0044281 77 0.013
phosphorus metabolic process GO:0006793 109 0.013
ribonucleoside monophosphate catabolic process GO:0009158 4 0.013
neuron projection development GO:0031175 180 0.013
atp catabolic process GO:0006200 4 0.013
microtubule based process GO:0007017 60 0.013
regulation of glucose transport GO:0010827 1 0.013
nuclear migration GO:0007097 3 0.013
hatching GO:0035188 4 0.013
striated muscle cell development GO:0055002 108 0.013
regulation of anatomical structure morphogenesis GO:0022603 130 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.012
regulation of protein localization to plasma membrane GO:1903076 1 0.012
chemotaxis GO:0006935 104 0.012
secondary metabolic process GO:0019748 3 0.012
catabolic process GO:0009056 32 0.012
Yeast
positive regulation of cellular metabolic process GO:0031325 94 0.012
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.012
negative regulation of protein import into nucleus GO:0042308 2 0.012
negative regulation of intracellular transport GO:0032387 3 0.012
eye development GO:0001654 277 0.012
cytokinetic process GO:0032506 2 0.012
response to glucocorticoid GO:0051384 1 0.012
neurotransmitter secretion GO:0007269 2 0.012
regulation of mitotic cell cycle GO:0007346 25 0.012
macromolecular complex subunit organization GO:0043933 74 0.012
response to corticosteroid GO:0031960 1 0.012
negative regulation of intracellular protein transport GO:0090317 3 0.012
positive regulation of cell activation GO:0050867 1 0.012
olfactory lobe development GO:0021988 4 0.012
lymphocyte proliferation GO:0046651 1 0.011
regulation of gtpase activity GO:0043087 2 0.011
regulation of protein polymerization GO:0032271 2 0.011
regulation of hormone secretion GO:0046883 2 0.011
mitochondrial transport GO:0006839 2 0.011
purine nucleoside monophosphate catabolic process GO:0009128 4 0.011
regulation of inflammatory response GO:0050727 2 0.011
response to nutrient GO:0007584 3 0.011
centrosome duplication GO:0051298 1 0.011
locomotor rhythm GO:0045475 3 0.011
organic substance transport GO:0071702 58 0.011
regulation of establishment of protein localization to plasma membrane GO:0090003 1 0.011
cellular response to starvation GO:0009267 1 0.011
production of molecular mediator of immune response GO:0002440 2 0.011
regulation of mitochondrion organization GO:0010821 1 0.011
response to uv GO:0009411 3 0.011
positive regulation of lipid metabolic process GO:0045834 1 0.011
negative regulation of cellular biosynthetic process GO:0031327 55 0.011
cell cycle GO:0007049 93 0.011
regulation of stem cell proliferation GO:0072091 2 0.011
neurotransmitter transport GO:0006836 2 0.011
regulation of erk1 and erk2 cascade GO:0070372 4 0.011
immune response GO:0006955 28 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.011
alpha amino acid metabolic process GO:1901605 3 0.011
regulation of synapse assembly GO:0051963 3 0.011
muscle structure development GO:0061061 196 0.011
positive regulation of macromolecule metabolic process GO:0010604 93 0.011
anterior posterior pattern specification GO:0009952 152 0.011
regulation of stem cell differentiation GO:2000736 4 0.010
regulation of synaptic plasticity GO:0048167 1 0.010
actin cytoskeleton organization GO:0030036 63 0.010
embryonic skeletal system morphogenesis GO:0048704 93 0.010
negative regulation of signaling GO:0023057 96 0.010
cellular response to oxygen levels GO:0071453 1 0.010
stem cell maintenance GO:0019827 4 0.010
negative regulation of secretion by cell GO:1903531 2 0.010
tissue remodeling GO:0048771 4 0.010
axon development GO:0061564 166 0.010
development of primary female sexual characteristics GO:0046545 4 0.010
positive regulation of cytoskeleton organization GO:0051495 3 0.010
actin filament polymerization GO:0030041 2 0.010
odontogenesis of dentin containing tooth GO:0042475 1 0.010
protein acylation GO:0043543 3 0.010
stem cell differentiation GO:0048863 117 0.010
signal transduction in absence of ligand GO:0038034 1 0.010
regulation of protein metabolic process GO:0051246 56 0.010
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.010
gene silencing GO:0016458 4 0.010
organic substance catabolic process GO:1901575 28 0.010
Yeast
negative regulation of sequestering of calcium ion GO:0051283 4 0.010
cytoskeleton organization GO:0007010 96 0.010

ube2d2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.020
disease of cellular proliferation DOID:14566 0 0.020
organ system cancer DOID:0050686 0 0.020
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.012