Danio rerio

0 known processes

serpind1

serine (or cysteine) proteinase inhibitor, clade D (heparin cofactor), member 1

(Aliases: HCII)

serpind1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of wound healing GO:0061041 2 0.158
response to external stimulus GO:0009605 264 0.109
response to external biotic stimulus GO:0043207 97 0.106
regulation of blood coagulation GO:0030193 1 0.103
regulation of cell substrate adhesion GO:0010810 1 0.101
larval development GO:0002164 2 0.086
negative regulation of response to stimulus GO:0048585 104 0.079
regulation of primary metabolic process GO:0080090 311 0.076
positive regulation of biological process GO:0048518 253 0.074
regulation of metabolic process GO:0019222 359 0.071
aging GO:0007568 2 0.067
cell substrate adhesion GO:0031589 4 0.066
response to other organism GO:0051707 97 0.059
cellular component disassembly GO:0022411 1 0.056
regulation of multicellular organism growth GO:0040014 4 0.056
generation of neurons GO:0048699 385 0.051
cellular response to estrogen stimulus GO:0071391 24 0.050
Zebrafish
immune system process GO:0002376 241 0.049
central nervous system development GO:0007417 387 0.049
response to biotic stimulus GO:0009607 97 0.049
regulation of tube size GO:0035150 2 0.048
cellular component movement GO:0006928 335 0.048
response to nutrient GO:0007584 3 0.048
regulation of macromolecule metabolic process GO:0060255 317 0.048
maintenance of location GO:0051235 4 0.047
regulation of blood pressure GO:0008217 1 0.047
regulation of blood vessel size GO:0050880 2 0.046
gene expression GO:0010467 252 0.046
response to chemical GO:0042221 320 0.046
Zebrafish
response to bacterium GO:0009617 58 0.045
ovulation cycle GO:0042698 2 0.045
muscle structure development GO:0061061 196 0.044
regulation of cellular metabolic process GO:0031323 320 0.044
positive regulation of cellular process GO:0048522 201 0.043
regulation of biological quality GO:0065008 263 0.043
response to stress GO:0006950 263 0.042
regulation of response to stimulus GO:0048583 269 0.042
protein metabolic process GO:0019538 183 0.041
positive regulation of transport GO:0051050 2 0.041
negative regulation of biological process GO:0048519 304 0.040
cellular protein catabolic process GO:0044257 4 0.040
heterocycle metabolic process GO:0046483 290 0.040
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.039
regulation of protein transport GO:0051223 3 0.037
female sex differentiation GO:0046660 4 0.037
regulation of nitrogen compound metabolic process GO:0051171 251 0.037
multicellular organism growth GO:0035264 4 0.036
cellular macromolecule metabolic process GO:0044260 391 0.036
vasculature development GO:0001944 278 0.035
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.035
development of primary female sexual characteristics GO:0046545 4 0.035
response to steroid hormone GO:0048545 35 0.035
Zebrafish
positive regulation of wound healing GO:0090303 1 0.034
regulation of inflammatory response GO:0050727 2 0.033
defense response GO:0006952 47 0.033
locomotion GO:0040011 313 0.033
positive regulation of secretion by cell GO:1903532 1 0.032
organic cyclic compound metabolic process GO:1901360 301 0.031
system process GO:0003008 185 0.031
blood coagulation fibrin clot formation GO:0072378 3 0.030
cellular nitrogen compound biosynthetic process GO:0044271 218 0.030
negative regulation of cellular process GO:0048523 283 0.030
regulation of establishment of protein localization GO:0070201 4 0.029
extrinsic apoptotic signaling pathway GO:0097191 3 0.029
rna metabolic process GO:0016070 219 0.028
developmental growth GO:0048589 166 0.028
response to organic cyclic compound GO:0014070 51 0.028
Zebrafish
inositol lipid mediated signaling GO:0048017 2 0.028
regulation of signal transduction GO:0009966 225 0.027
nephron tubule morphogenesis GO:0072078 1 0.027
transcription dna templated GO:0006351 181 0.026
epithelial cell differentiation GO:0030855 116 0.026
single organism localization GO:1902578 225 0.026
cellular amine metabolic process GO:0044106 2 0.026
regulation of biosynthetic process GO:0009889 250 0.026
regulation of systemic arterial blood pressure GO:0003073 1 0.025
neurotransmitter transport GO:0006836 2 0.025
cell motility GO:0048870 244 0.025
cerebellar cortex formation GO:0021697 5 0.025
cellular response to chemical stimulus GO:0070887 157 0.025
Zebrafish
regulation of signaling GO:0023051 235 0.024
cellular protein metabolic process GO:0044267 129 0.024
transport GO:0006810 220 0.024
positive regulation of secretion GO:0051047 1 0.023
organic cyclic compound biosynthetic process GO:1901362 223 0.023
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.023
regulation of hemostasis GO:1900046 1 0.023
hormone transport GO:0009914 2 0.023
regulation of cellular amino acid metabolic process GO:0006521 0 0.023
regulation of localization GO:0032879 104 0.022
regulation of cytokine production GO:0001817 3 0.022
positive regulation of catabolic process GO:0009896 4 0.022
hepaticobiliary system development GO:0061008 98 0.022
response to lipid GO:0033993 60 0.022
Zebrafish
positive regulation of cellular component biogenesis GO:0044089 3 0.022
ovulation cycle process GO:0022602 2 0.022
cellular response to endogenous stimulus GO:0071495 68 0.022
Zebrafish
cellular response to extracellular stimulus GO:0031668 2 0.022
nucleobase containing compound metabolic process GO:0006139 274 0.021
renal system process involved in regulation of systemic arterial blood pressure GO:0003071 1 0.021
cell surface receptor signaling pathway GO:0007166 325 0.021
response to organic substance GO:0010033 153 0.021
Zebrafish
hemostasis GO:0007599 13 0.021
circulatory system process GO:0003013 87 0.021
phagocytosis GO:0006909 3 0.021
cell migration GO:0016477 237 0.021
growth GO:0040007 174 0.021
localization of cell GO:0051674 244 0.021
protein secretion GO:0009306 1 0.021
homeostatic process GO:0042592 142 0.021
cellular amino acid metabolic process GO:0006520 7 0.021
cell matrix adhesion GO:0007160 4 0.020
positive regulation of cytokine production GO:0001819 2 0.020
lipid storage GO:0019915 1 0.020
signal transduction GO:0007165 455 0.020
synaptic growth at neuromuscular junction GO:0051124 2 0.020
hormone secretion GO:0046879 2 0.020
cellular nitrogen compound metabolic process GO:0034641 290 0.020
positive regulation of cell adhesion GO:0045785 1 0.020
protein polymerization GO:0051258 4 0.020
female gonad development GO:0008585 4 0.020
response to glucose GO:0009749 3 0.019
negative regulation of defense response GO:0031348 2 0.019
regulation of synapse assembly GO:0051963 3 0.019
regulation of protein catabolic process GO:0042176 1 0.019
blood coagulation GO:0007596 12 0.019
peptidyl serine phosphorylation GO:0018105 1 0.019
regulation of gene expression GO:0010468 265 0.018
heterocycle biosynthetic process GO:0018130 215 0.018
amine metabolic process GO:0009308 2 0.018
regulation of cellular biosynthetic process GO:0031326 245 0.018
regulation of fatty acid metabolic process GO:0019217 1 0.018
positive regulation of blood circulation GO:1903524 2 0.018
nucleobase containing compound biosynthetic process GO:0034654 205 0.018
cellular aromatic compound metabolic process GO:0006725 295 0.018
organic substance biosynthetic process GO:1901576 289 0.018
blood vessel morphogenesis GO:0048514 216 0.018
response to hormone GO:0009725 48 0.018
Zebrafish
regulation of cellular amine metabolic process GO:0033238 0 0.018
positive regulation of cellular catabolic process GO:0031331 3 0.018
lipid catabolic process GO:0016042 4 0.018
blood vessel development GO:0001568 246 0.018
regulation of multicellular organismal development GO:2000026 223 0.017
central nervous system neuron differentiation GO:0021953 74 0.017
biosynthetic process GO:0009058 294 0.017
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.017
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.017
embryonic organ development GO:0048568 381 0.017
multicellular organismal response to stress GO:0033555 2 0.017
multi organism process GO:0051704 134 0.017
meiotic nuclear division GO:0007126 4 0.017
astrocyte differentiation GO:0048708 1 0.017
phosphorus metabolic process GO:0006793 109 0.017
rna biosynthetic process GO:0032774 181 0.017
regulation of cell communication GO:0010646 232 0.017
extracellular structure organization GO:0043062 27 0.017
single organism transport GO:0044765 206 0.016
cellular response to organic substance GO:0071310 105 0.016
Zebrafish
protein import into nucleus GO:0006606 3 0.016
epithelial tube morphogenesis GO:0060562 148 0.016
regulation of macromolecule biosynthetic process GO:0010556 225 0.016
neuron differentiation GO:0030182 353 0.016
anatomical structure homeostasis GO:0060249 36 0.016
response to wounding GO:0009611 116 0.016
positive regulation of cell substrate adhesion GO:0010811 1 0.016
phosphatidylinositol mediated signaling GO:0048015 2 0.016
cellular response to nutrient levels GO:0031669 2 0.016
positive regulation of cellular amine metabolic process GO:0033240 0 0.016
exocytosis GO:0006887 1 0.016
regulation of dna replication GO:0006275 3 0.016
stem cell division GO:0017145 1 0.016
lymphocyte proliferation GO:0046651 1 0.016
defense response to other organism GO:0098542 33 0.016
muscle cell differentiation GO:0042692 139 0.016
protein localization to nucleus GO:0034504 3 0.015
ubiquitin dependent protein catabolic process GO:0006511 3 0.015
single organism metabolic process GO:0044710 217 0.015
response to carbohydrate GO:0009743 3 0.015
regulation of synapse organization GO:0050807 3 0.015
regulation of organ growth GO:0046620 3 0.015
response to monosaccharide GO:0034284 3 0.015
negative regulation of dna metabolic process GO:0051053 4 0.015
regulation of rna biosynthetic process GO:2001141 213 0.015
regulation of metal ion transport GO:0010959 4 0.015
positive regulation of response to stimulus GO:0048584 80 0.015
post embryonic organ development GO:0048569 4 0.015
leukocyte proliferation GO:0070661 1 0.015
embryo development ending in birth or egg hatching GO:0009792 271 0.015
mononuclear cell proliferation GO:0032943 1 0.015
negative regulation of dna replication GO:0008156 2 0.015
regulation of reproductive process GO:2000241 4 0.015
regulation of transcription dna templated GO:0006355 213 0.015
small molecule metabolic process GO:0044281 77 0.015
cerebellar granular layer morphogenesis GO:0021683 3 0.015
wound healing GO:0042060 90 0.014
head development GO:0060322 303 0.014
proteolysis GO:0006508 38 0.014
positive regulation of multicellular organismal process GO:0051240 52 0.014
negative regulation of sequestering of calcium ion GO:0051283 4 0.014
blood circulation GO:0008015 87 0.014
cell morphogenesis GO:0000902 289 0.014
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.014
cellular response to organic cyclic compound GO:0071407 38 0.014
Zebrafish
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.014
biomineral tissue development GO:0031214 13 0.014
cellular macromolecule biosynthetic process GO:0034645 224 0.014
digestive system development GO:0055123 289 0.014
stem cell maintenance GO:0019827 4 0.014
lymphangiogenesis GO:0001946 25 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.014
regulation of cytoplasmic transport GO:1903649 4 0.013
macromolecule biosynthetic process GO:0009059 227 0.013
regulation of hormone levels GO:0010817 21 0.013
regulation of rna metabolic process GO:0051252 224 0.013
programmed cell death GO:0012501 119 0.013
regulation of protein complex assembly GO:0043254 3 0.013
negative regulation of protein import into nucleus GO:0042308 2 0.013
regulation of cell projection assembly GO:0060491 4 0.013
regulation of multicellular organismal process GO:0051239 277 0.013
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.013
regulation of coagulation GO:0050818 2 0.013
heart morphogenesis GO:0003007 156 0.013
cellular response to external stimulus GO:0071496 2 0.013
fatty acid biosynthetic process GO:0006633 4 0.013
regulation of hormone secretion GO:0046883 2 0.013
regulation of cell activation GO:0050865 1 0.013
secondary metabolic process GO:0019748 3 0.013
oxoacid metabolic process GO:0043436 31 0.013
regulation of locomotion GO:0040012 55 0.013
regulation of cellular ketone metabolic process GO:0010565 7 0.013
positive regulation of epithelial cell migration GO:0010634 2 0.012
heart development GO:0007507 313 0.012
cellular response to starvation GO:0009267 1 0.012
regulation of circadian rhythm GO:0042752 4 0.012
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.012
tissue remodeling GO:0048771 4 0.012
nucleic acid metabolic process GO:0090304 244 0.012
cell projection organization GO:0030030 284 0.012
regulation of cell adhesion GO:0030155 15 0.012
positive regulation of cytoskeleton organization GO:0051495 3 0.012
cerebellar granular layer formation GO:0021684 3 0.012
ventricular cardiac muscle tissue development GO:0003229 3 0.012
regulation of cellular protein catabolic process GO:1903362 1 0.012
carbohydrate homeostasis GO:0033500 1 0.012
apoptotic process involved in development GO:1902742 2 0.012
erk1 and erk2 cascade GO:0070371 4 0.012
digestive tract development GO:0048565 265 0.012
mycotoxin metabolic process GO:0043385 1 0.012
cellular biosynthetic process GO:0044249 286 0.012
liver development GO:0001889 96 0.012
regulation of cellular component movement GO:0051270 55 0.012
morphogenesis of an epithelium GO:0002009 333 0.012
muscle organ development GO:0007517 101 0.012
modification dependent macromolecule catabolic process GO:0043632 3 0.012
renal tubule morphogenesis GO:0061333 1 0.012
negative regulation of cell communication GO:0010648 96 0.012
nucleocytoplasmic transport GO:0006913 4 0.012
nucleic acid templated transcription GO:0097659 181 0.012
tissue regeneration GO:0042246 74 0.011
regulation of erk1 and erk2 cascade GO:0070372 4 0.011
neurotransmitter secretion GO:0007269 2 0.011
regulation of jak stat cascade GO:0046425 3 0.011
aromatic compound biosynthetic process GO:0019438 217 0.011
spermatid differentiation GO:0048515 2 0.011
peptidyl serine modification GO:0018209 2 0.011
chemosensory behavior GO:0007635 1 0.011
tube morphogenesis GO:0035239 349 0.011
protein complex biogenesis GO:0070271 30 0.011
hormone biosynthetic process GO:0042446 3 0.011
negative regulation of protein phosphorylation GO:0001933 4 0.011
peptide transport GO:0015833 1 0.011
response to hexose GO:0009746 3 0.011
negative regulation of nuclear division GO:0051784 3 0.011
mesenchymal cell differentiation GO:0048762 87 0.011
biological adhesion GO:0022610 40 0.011
single organism nuclear import GO:1902593 3 0.011
response to cold GO:0009409 4 0.011
sequestering of metal ion GO:0051238 3 0.011
protein import GO:0017038 3 0.011
negative regulation of cell adhesion GO:0007162 6 0.011
proteasomal protein catabolic process GO:0010498 2 0.011
carboxylic acid metabolic process GO:0019752 22 0.011
regeneration GO:0031099 91 0.011
defense response to fungus GO:0050832 2 0.011
synaptic transmission cholinergic GO:0007271 4 0.010
regulation of cell shape GO:0008360 1 0.010
cellular response to molecule of bacterial origin GO:0071219 3 0.010
developmental programmed cell death GO:0010623 4 0.010
response to vitamin GO:0033273 3 0.010
negative regulation of signal transduction GO:0009968 94 0.010
extracellular matrix organization GO:0030198 27 0.010
sequestering of calcium ion GO:0051208 3 0.010
regulation of synaptic plasticity GO:0048167 1 0.010
response to xenobiotic stimulus GO:0009410 45 0.010
protein homooligomerization GO:0051260 3 0.010
embryonic heart tube morphogenesis GO:0003143 108 0.010
regulation of nucleocytoplasmic transport GO:0046822 2 0.010
endothelial cell fate commitment GO:0060839 3 0.010
positive regulation of cell activation GO:0050867 1 0.010
establishment of localization GO:0051234 244 0.010
nuclear import GO:0051170 3 0.010
regulation of developmental process GO:0050793 247 0.010
establishment of protein localization to organelle GO:0072594 4 0.010

serpind1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.056
cardiovascular system disease DOID:1287 0 0.042
disease of metabolism DOID:0014667 0 0.027
immune system disease DOID:2914 0 0.027
hematopoietic system disease DOID:74 0 0.027
amyloidosis DOID:9120 0 0.013
acquired metabolic disease DOID:0060158 0 0.013
inherited metabolic disorder DOID:655 0 0.012