Danio rerio

0 known processes

hddc3

HD domain containing 3

(Aliases: MESH1,zgc:110184)

hddc3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
aging GO:0007568 2 0.162
phagocytosis GO:0006909 3 0.143
immune system development GO:0002520 191 0.122
nucleocytoplasmic transport GO:0006913 4 0.105
maintenance of location GO:0051235 4 0.102
Worm
hematopoietic or lymphoid organ development GO:0048534 191 0.095
fertilization GO:0009566 3 0.082
biosynthetic process GO:0009058 294 0.077
larval development GO:0002164 2 0.074
sensory organ development GO:0007423 393 0.074
cellular macromolecule biosynthetic process GO:0034645 224 0.068
transmembrane transport GO:0055085 120 0.064
regulation of striated muscle contraction GO:0006942 2 0.063
immune system process GO:0002376 241 0.061
regulation of establishment of protein localization GO:0070201 4 0.060
nuclear export GO:0051168 1 0.056
response to other organism GO:0051707 97 0.056
morphogenesis of an epithelium GO:0002009 333 0.056
single fertilization GO:0007338 3 0.055
single organism localization GO:1902578 225 0.054
ribonucleoside monophosphate catabolic process GO:0009158 4 0.054
establishment of localization GO:0051234 244 0.051
lipid storage GO:0019915 1 0.050
Worm
response to drug GO:0042493 3 0.049
phagocytosis engulfment GO:0006911 1 0.048
regulation of gene expression GO:0010468 265 0.048
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.046
hemopoiesis GO:0030097 183 0.046
cytoskeleton dependent cytokinesis GO:0061640 3 0.046
purine nucleoside monophosphate catabolic process GO:0009128 4 0.045
membrane fusion GO:0061025 2 0.044
nuclear transport GO:0051169 4 0.043
exocytosis GO:0006887 1 0.043
nuclear import GO:0051170 3 0.042
single organism transport GO:0044765 206 0.041
embryo development ending in birth or egg hatching GO:0009792 271 0.041
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.040
glucose homeostasis GO:0042593 1 0.040
cellular macromolecule metabolic process GO:0044260 391 0.040
regulation of biological quality GO:0065008 263 0.039
Worm
transport GO:0006810 220 0.038
female gonad development GO:0008585 4 0.037
regulation of cell shape GO:0008360 1 0.037
cellular biosynthetic process GO:0044249 286 0.037
ion transmembrane transport GO:0034220 91 0.037
organic substance biosynthetic process GO:1901576 289 0.036
regulation of blood pressure GO:0008217 1 0.036
regulation of cytoplasmic transport GO:1903649 4 0.036
tube morphogenesis GO:0035239 349 0.035
response to biotic stimulus GO:0009607 97 0.035
ion transport GO:0006811 114 0.034
regulation of protein import into nucleus GO:0042306 2 0.034
positive regulation of transport GO:0051050 2 0.034
regulation of protein transport GO:0051223 3 0.034
cytokinesis GO:0000910 3 0.033
regulation of cell activation GO:0050865 1 0.033
synaptic growth at neuromuscular junction GO:0051124 2 0.033
negative regulation of intracellular transport GO:0032387 3 0.033
digestive system development GO:0055123 289 0.033
nitrogen compound metabolic process GO:0006807 319 0.033
regulation of metal ion transport GO:0010959 4 0.032
signal transduction GO:0007165 455 0.032
negative regulation of protein transport GO:0051224 3 0.032
protein targeting to nucleus GO:0044744 3 0.032
membrane invagination GO:0010324 1 0.032
homeostatic process GO:0042592 142 0.032
single organism nuclear import GO:1902593 3 0.031
response to stress GO:0006950 263 0.031
ameboidal type cell migration GO:0001667 143 0.031
heterocycle metabolic process GO:0046483 290 0.031
cell part morphogenesis GO:0032990 246 0.030
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.030
response to chemical GO:0042221 320 0.030
embryonic organ development GO:0048568 381 0.030
positive regulation of macromolecule metabolic process GO:0010604 93 0.030
regulation of multicellular organismal process GO:0051239 277 0.030
spermatid differentiation GO:0048515 2 0.030
guanosine containing compound metabolic process GO:1901068 4 0.029
myeloid cell differentiation GO:0030099 86 0.029
gtp metabolic process GO:0046039 4 0.028
rna localization GO:0006403 4 0.028
spermatid development GO:0007286 2 0.028
cellular nitrogen compound metabolic process GO:0034641 290 0.028
gtp catabolic process GO:0006184 2 0.027
transcription dna templated GO:0006351 181 0.027
regulation of primary metabolic process GO:0080090 311 0.027
regulation of cytokine production GO:0001817 3 0.027
protein import GO:0017038 3 0.027
establishment of protein localization to organelle GO:0072594 4 0.027
positive regulation of biological process GO:0048518 253 0.026
regulation of nucleocytoplasmic transport GO:0046822 2 0.026
response to external biotic stimulus GO:0043207 97 0.026
fatty acid oxidation GO:0019395 1 0.026
cellular response to starvation GO:0009267 1 0.026
regulation of synapse assembly GO:0051963 3 0.026
protein localization to nucleus GO:0034504 3 0.026
locomotion GO:0040011 313 0.026
eye development GO:0001654 277 0.025
organonitrogen compound metabolic process GO:1901564 74 0.025
regulation of response to cytokine stimulus GO:0060759 3 0.025
protein import into nucleus GO:0006606 3 0.025
positive regulation of cell cycle GO:0045787 3 0.025
cellular response to chemical stimulus GO:0070887 157 0.025
growth GO:0040007 174 0.025
digestive tract development GO:0048565 265 0.024
regulation of immune response GO:0050776 14 0.024
regulation of synapse organization GO:0050807 3 0.024
response to ketone GO:1901654 1 0.024
generation of neurons GO:0048699 385 0.024
lipid oxidation GO:0034440 1 0.023
regulation of multicellular organismal development GO:2000026 223 0.023
regulation of dendrite development GO:0050773 3 0.023
cellular amino acid metabolic process GO:0006520 7 0.023
actin filament based movement GO:0030048 1 0.023
regulation of anatomical structure morphogenesis GO:0022603 130 0.023
cell motility GO:0048870 244 0.023
negative regulation of multicellular organismal process GO:0051241 69 0.023
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.022
female sex differentiation GO:0046660 4 0.022
cellular component morphogenesis GO:0032989 336 0.022
response to organic substance GO:0010033 153 0.022
regulation of transmembrane transporter activity GO:0022898 2 0.022
modification dependent protein catabolic process GO:0019941 3 0.022
regulation of transcription dna templated GO:0006355 213 0.022
positive regulation of cellular process GO:0048522 201 0.022
cellular response to extracellular stimulus GO:0031668 2 0.022
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.022
intracellular mrna localization GO:0008298 1 0.021
macromolecule biosynthetic process GO:0009059 227 0.021
localization of cell GO:0051674 244 0.021
positive regulation of metabolic process GO:0009893 108 0.021
regulation of membrane potential GO:0042391 23 0.021
regulation of intracellular protein transport GO:0033157 3 0.021
cell migration GO:0016477 237 0.021
nucleic acid metabolic process GO:0090304 244 0.021
regulation of metabolic process GO:0019222 359 0.021
regulation of cellular amine metabolic process GO:0033238 0 0.021
striated muscle cell differentiation GO:0051146 129 0.020
apoptotic process GO:0006915 116 0.020
production of molecular mediator of immune response GO:0002440 2 0.020
erythrocyte differentiation GO:0030218 54 0.020
organic cyclic compound metabolic process GO:1901360 301 0.020
regulation of protein polymerization GO:0032271 2 0.020
regulation of nucleic acid templated transcription GO:1903506 213 0.020
protein metabolic process GO:0019538 183 0.020
erythrocyte homeostasis GO:0034101 55 0.020
carboxylic acid metabolic process GO:0019752 22 0.020
cellular amine metabolic process GO:0044106 2 0.020
epithelial cell differentiation GO:0030855 116 0.019
gastrulation GO:0007369 208 0.019
regulation of developmental process GO:0050793 247 0.019
apical junction assembly GO:0043297 1 0.019
regulation of synaptic plasticity GO:0048167 1 0.019
regulation of protein targeting GO:1903533 2 0.019
actin mediated cell contraction GO:0070252 1 0.019
stem cell maintenance GO:0019827 4 0.019
positive regulation of catabolic process GO:0009896 4 0.019
cell projection morphogenesis GO:0048858 244 0.019
regulation of reproductive process GO:2000241 4 0.019
lipid catabolic process GO:0016042 4 0.019
regulation of protein localization to nucleus GO:1900180 2 0.019
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.019
system process GO:0003008 185 0.018
regulation of macromolecule metabolic process GO:0060255 317 0.018
cellular protein catabolic process GO:0044257 4 0.018
negative regulation of cytoplasmic transport GO:1903650 2 0.018
regulation of biosynthetic process GO:0009889 250 0.018
cellular response to external stimulus GO:0071496 2 0.018
regulation of erk1 and erk2 cascade GO:0070372 4 0.018
cell migration involved in gastrulation GO:0042074 79 0.018
regulation of cytokine mediated signaling pathway GO:0001959 3 0.018
dna templated transcription elongation GO:0006354 3 0.017
regulation of ion transmembrane transporter activity GO:0032412 2 0.017
regulation of rna biosynthetic process GO:2001141 213 0.017
defense response GO:0006952 47 0.017
response to bacterium GO:0009617 58 0.017
small molecule metabolic process GO:0044281 77 0.017
cellular component assembly GO:0022607 170 0.017
regulation of actin filament based movement GO:1903115 1 0.017
cellular localization GO:0051641 97 0.017
positive regulation of protein complex assembly GO:0031334 2 0.017
striated muscle tissue development GO:0014706 110 0.017
cellular aromatic compound metabolic process GO:0006725 295 0.017
inorganic ion transmembrane transport GO:0098660 57 0.017
single organism membrane fusion GO:0044801 2 0.017
wound healing GO:0042060 90 0.017
positive regulation of cellular component biogenesis GO:0044089 3 0.017
posterior lateral line system development GO:0048915 46 0.017
mechanosensory lateral line system development GO:0048881 49 0.017
cellular protein modification process GO:0006464 100 0.016
carbohydrate derivative metabolic process GO:1901135 61 0.016
pigmentation GO:0043473 85 0.016
carbohydrate homeostasis GO:0033500 1 0.016
gene expression GO:0010467 252 0.016
organic acid metabolic process GO:0006082 31 0.016
determination of heart left right asymmetry GO:0061371 117 0.016
cation transmembrane transport GO:0098655 65 0.016
amine metabolic process GO:0009308 2 0.016
oxoacid metabolic process GO:0043436 31 0.016
regulation of epithelial cell proliferation GO:0050678 3 0.016
rna metabolic process GO:0016070 219 0.016
cellular response to nutrient levels GO:0031669 2 0.016
heterocycle biosynthetic process GO:0018130 215 0.016
regulation of calcium ion transport GO:0051924 2 0.016
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.016
organelle organization GO:0006996 227 0.016
cell death GO:0008219 121 0.016
intracellular receptor signaling pathway GO:0030522 30 0.016
embryonic hemopoiesis GO:0035162 53 0.016
cellular response to organic substance GO:0071310 105 0.016
single organism metabolic process GO:0044710 217 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
cell morphogenesis involved in differentiation GO:0000904 195 0.015
guanosine containing compound catabolic process GO:1901069 2 0.015
cellular component biogenesis GO:0044085 178 0.015
regulation of cellular component movement GO:0051270 55 0.015
cellular protein metabolic process GO:0044267 129 0.015
development of primary female sexual characteristics GO:0046545 4 0.015
cell morphogenesis GO:0000902 289 0.015
negative regulation of protein localization to nucleus GO:1900181 2 0.015
multi organism process GO:0051704 134 0.015
alternative mrna splicing via spliceosome GO:0000380 1 0.015
negative regulation of reproductive process GO:2000242 3 0.015
transmission of nerve impulse GO:0019226 19 0.015
chordate embryonic development GO:0043009 271 0.015
negative regulation of immune response GO:0050777 2 0.015
stem cell proliferation GO:0072089 4 0.015
protein acetylation GO:0006473 2 0.015
atp catabolic process GO:0006200 4 0.015
multicellular organism growth GO:0035264 4 0.015
protein acylation GO:0043543 3 0.015
regulation of macromolecule biosynthetic process GO:0010556 225 0.015
viral process GO:0016032 1 0.015
proteasomal protein catabolic process GO:0010498 2 0.015
sequestering of calcium ion GO:0051208 3 0.015
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.014
regulation of response to stimulus GO:0048583 269 0.014
regulation of localization GO:0032879 104 0.014
developmental growth GO:0048589 166 0.014
cellular component movement GO:0006928 335 0.014
pancreas development GO:0031016 84 0.014
nucleic acid templated transcription GO:0097659 181 0.014
nucleoside monophosphate catabolic process GO:0009125 4 0.014
blood circulation GO:0008015 87 0.014
positive regulation of cytoskeleton organization GO:0051495 3 0.014
regulation of neuronal synaptic plasticity GO:0048168 1 0.014
axonogenesis GO:0007409 152 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.014
regulation of protein complex assembly GO:0043254 3 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.014
organelle fusion GO:0048284 3 0.014
osteoclast differentiation GO:0030316 1 0.014
organic cyclic compound biosynthetic process GO:1901362 223 0.014
cation homeostasis GO:0055080 33 0.014
chemical homeostasis GO:0048878 49 0.014
actin filament polymerization GO:0030041 2 0.014
negative regulation of biological process GO:0048519 304 0.014
peptidyl serine modification GO:0018209 2 0.014
aromatic compound biosynthetic process GO:0019438 217 0.014
organic acid catabolic process GO:0016054 3 0.014
regulation of system process GO:0044057 40 0.014
neuron development GO:0048666 262 0.013
erk1 and erk2 cascade GO:0070371 4 0.013
alpha amino acid metabolic process GO:1901605 3 0.013
mitotic cytokinesis GO:0000281 3 0.013
g2 m transition of mitotic cell cycle GO:0000086 4 0.013
compound eye development GO:0048749 2 0.013
regulation of meiotic cell cycle GO:0051445 1 0.013
nucleobase containing compound metabolic process GO:0006139 274 0.013
determination of bilateral symmetry GO:0009855 204 0.013
embryonic skeletal system development GO:0048706 97 0.013
ovulation cycle GO:0042698 2 0.013
cytosolic calcium ion transport GO:0060401 3 0.013
regulation of signal transduction GO:0009966 225 0.013
positive regulation of secretion by cell GO:1903532 1 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.013
regulation of cardiac muscle contraction GO:0055117 2 0.013
peptidyl lysine acetylation GO:0018394 2 0.013
modification dependent macromolecule catabolic process GO:0043632 3 0.013
regulation of neurogenesis GO:0050767 87 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.013
cell substrate adhesion GO:0031589 4 0.013
protein stabilization GO:0050821 2 0.013
myeloid leukocyte differentiation GO:0002573 15 0.013
startle response GO:0001964 4 0.013
cellular response to lipid GO:0071396 39 0.013
stem cell division GO:0017145 1 0.013
axon development GO:0061564 166 0.012
programmed cell death GO:0012501 119 0.012
specification of symmetry GO:0009799 204 0.012
stem cell differentiation GO:0048863 117 0.012
sensory organ morphogenesis GO:0090596 200 0.012
negative regulation of cellular process GO:0048523 283 0.012
regulation of multicellular organism growth GO:0040014 4 0.012
pole plasm assembly GO:0007315 4 0.012
positive regulation of protein polymerization GO:0032273 2 0.012
negative regulation of defense response GO:0031348 2 0.012
gland development GO:0048732 143 0.012
establishment of localization in cell GO:0051649 77 0.012
muscle cell differentiation GO:0042692 139 0.012
response to endogenous stimulus GO:0009719 83 0.012
epithelial tube morphogenesis GO:0060562 148 0.012
lymphocyte proliferation GO:0046651 1 0.012
negative regulation of synapse assembly GO:0051964 2 0.012
cell projection organization GO:0030030 284 0.012
protein polymerization GO:0051258 4 0.012
response to external stimulus GO:0009605 264 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.012
cytoplasm organization GO:0007028 4 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
ubiquitin dependent protein catabolic process GO:0006511 3 0.012
antimicrobial humoral response GO:0019730 2 0.012
positive regulation of translation GO:0045727 1 0.012
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.012
phosphate containing compound metabolic process GO:0006796 108 0.012
eye morphogenesis GO:0048592 144 0.012
calcium ion dependent exocytosis GO:0017156 1 0.012
extrinsic apoptotic signaling pathway GO:0097191 3 0.012
response to estrogen GO:0043627 27 0.012
regulation of immune system process GO:0002682 34 0.012
cellular response to endogenous stimulus GO:0071495 68 0.011
positive regulation of secretion GO:0051047 1 0.011
internal protein amino acid acetylation GO:0006475 2 0.011
sequestering of metal ion GO:0051238 3 0.011
striated muscle cell development GO:0055002 108 0.011
positive regulation of nucleoside metabolic process GO:0045979 1 0.011
protein dephosphorylation GO:0006470 3 0.011
death GO:0016265 121 0.011
regulation of transporter activity GO:0032409 2 0.011
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.011
spindle assembly involved in mitosis GO:0090307 1 0.011
regulation of dna templated transcription elongation GO:0032784 3 0.011
mitochondrion organization GO:0007005 4 0.011
negative regulation of secretion by cell GO:1903531 2 0.011
negative regulation of catabolic process GO:0009895 3 0.011
digestive tract morphogenesis GO:0048546 231 0.011
regulation of cell communication GO:0010646 232 0.011
regulation of nucleoside metabolic process GO:0009118 2 0.011
double strand break repair GO:0006302 3 0.011
regulation of cellular biosynthetic process GO:0031326 245 0.011
regulation of sequestering of calcium ion GO:0051282 4 0.011
epidermis morphogenesis GO:0048730 4 0.011
regulation of protein ubiquitination GO:0031396 3 0.011
negative regulation of multi organism process GO:0043901 3 0.011
regulation of cellular ketone metabolic process GO:0010565 7 0.011
regulation of chromosome segregation GO:0051983 1 0.011
protein complex disassembly GO:0043241 1 0.011
calcium ion transport into cytosol GO:0060402 3 0.011
long chain fatty acid biosynthetic process GO:0042759 1 0.010
rna biosynthetic process GO:0032774 181 0.010
establishment of rna localization GO:0051236 3 0.010
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.010
peptide metabolic process GO:0006518 1 0.010
cellular ketone metabolic process GO:0042180 11 0.010
internal peptidyl lysine acetylation GO:0018393 2 0.010
regulation of nucleotide catabolic process GO:0030811 2 0.010
response to monosaccharide GO:0034284 3 0.010
neurotransmitter transport GO:0006836 2 0.010
meiotic cell cycle process GO:1903046 3 0.010
nucleoside phosphate metabolic process GO:0006753 28 0.010
single organism organelle organization GO:1902589 199 0.010
neuron projection development GO:0031175 180 0.010
embryonic cranial skeleton morphogenesis GO:0048701 90 0.010
oxidation reduction process GO:0055114 41 0.010
neuron projection morphogenesis GO:0048812 161 0.010
protein modification process GO:0036211 100 0.010
negative regulation of cellular catabolic process GO:0031330 3 0.010
actin polymerization or depolymerization GO:0008154 2 0.010
cellular transition metal ion homeostasis GO:0046916 3 0.010

hddc3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.029
disease of anatomical entity DOID:7 0 0.025
immune system disease DOID:2914 0 0.016
cancer DOID:162 0 0.016
organ system cancer DOID:0050686 0 0.015
disease of metabolism DOID:0014667 0 0.014
nervous system disease DOID:863 0 0.010